ATG12

autophagy related 12
General Information
Name autophagy related 12
Alias
  • ubiquitin-like protein ATG12
  • APG12 autophagy 12-like
  • ATG12 autophagy related 12 homolog
  • Apg12 (autophagy, yeast) homolog
Synonyms APG12 APG12L FBR93 HAPG12
Gene_family Autophagy related
organism Homo sapiens
entrez_id 9140
location 5q22.3
transcript_count 5
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008]
      Stringdb Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes
      nextProt Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ATG12 BioGRID XPO7 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RB1CC1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    ATG12 BioGRID PRKACA GeneID BioGRID Biochemical Activity
    ATG12 BioGRID ESR2 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID NLRP6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    ATG12 BioGRID SH3BGRL GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID ATG5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Proximity Label-MS
    ATG12 BioGRID ATG16L1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
    ATG12 BioGRID ATG3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex; Two-hybrid
    ATG12 BioGRID TECPR1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID EMC8 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID AIMP1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RPS12 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RPS8 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RPL38 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RPL32 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RPL11 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID BIRC5 GeneID BioGRID Affinity Capture-Western; Co-localization
    ATG12 BioGRID MAVS GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID ATG10 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID RAB33B GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID KXD1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID ATG101 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID ATG13 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID RAB33A GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID KRT37 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID ULK1 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID CCDC12 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID CANT1 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SNX6 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID IARS2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SLC6A15 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID OCIAD1 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID RNFT1 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID NDUFAF4 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SNX5 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID VPS13A GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID GGA3 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID PHB2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID AFG3L2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID GCC2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SCAMP1 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID HGS GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SNAP23 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID NUMB GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID TPD52L2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID SLC12A2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID IGF2R GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID GOLGB1 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID GOLGA4 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID FLOT2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID EPHA2 GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID CPD GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID ATP5F1B GeneID BioGRID Proximity Label-MS
    ATG12 BioGRID MAP1LC3B GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID DOCK9 GeneID BioGRID Two-hybrid
    ATG12 BioGRID TRIM13 GeneID BioGRID Co-localization
    ATG12 BioGRID SERTAD1 GeneID BioGRID Two-hybrid
    ATG12 BioGRID SERTAD2 GeneID BioGRID Two-hybrid
    ATG12 BioGRID IER2 GeneID BioGRID Two-hybrid
    ATG12 BioGRID MEOX2 GeneID BioGRID Two-hybrid
    ATG12 BioGRID ATG7 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    ATG12 BioGRID WIPI2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    ATG12 BioGRID PSMD10 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID Atg3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    ATG12 BioGRID CRX GeneID BioGRID Two-hybrid
    ATG12 BioGRID FADD GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID EXOC4 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID Atg10 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID CAV1 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID WDFY3 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID APP GeneID BioGRID Reconstituted Complex
    ATG12 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID MCL1 GeneID BioGRID Affinity Capture-Western
    ATG12 BioGRID ATG4B GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID GABARAP GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID MAP1B GeneID BioGRID Affinity Capture-MS
    ATG12 Protein ATG10 GeneID HPRD None
    ATG12 Protein ATG5 GeneID HPRD None
    ATG12 Protein KRTAP4-12 GeneID HPRD None
    ATG12 Protein ATG7 GeneID HPRD None
    ATG12 Protein ATG3 GeneID HPRD None
    ATG12 Protein PLSCR1 GeneID HPRD None
    ATG12 Protein MDFI GeneID HPRD None
    ATG12 Protein PTK2 GeneID HPRD None
    ATG12 BioGRID DHX36 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID OTUD4 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID SF3B1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID SF3A1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID AUP1 GeneID BioGRID Affinity Capture-MS
    ATG12 BioGRID KRTAP4-12 GeneID BioGRID Two-hybrid
    ATG12 BioGRID PTK2 GeneID BioGRID Two-hybrid
    ATG12 BioGRID PLSCR1 GeneID BioGRID Two-hybrid
    ATG12 BioGRID MDFI GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    ATG12 BCL2L15 0 0 91 150 1 1
    ATG12 TBPL1 0 0 0 200 1 1
    ATG12 RRAGD 0 0 95 200 1 1
    ATG12 SCD5 0 0 0 196 1 1
    ATG12 TBKBP1 0 0 181 181 1 1
    ATG12 SEC62 0 0 123 162 1 1
    ATG12 TMX2 0 0 0 163 1 1
    ATG12 PSMD2 0 0 95 203 1 1
    ATG12 NOD1 0 0 363 377 1 1
    ATG12 CHST13 0 0 0 363 1 1
    ATG12 BECN1 131 650 876 988 1 2
    ATG12 MAPT 0 0 207 207 1 2
    ATG12 STX10 0 0 0 206 1 1
    ATG12 ZC3HAV1 0 0 66 159 1 1
    ATG12 ABCB1 0 0 139 152 1 1
    ATG12 DERL1 0 0 74 161 1 1
    ATG12 SNX4 0 0 66 236 1 1
    ATG12 ARF6 0 0 110 201 1 1
    ATG12 PEX3 0 0 209 227 1 2
    ATG12 PIK3CB 0 0 112 251 1 1
    ATG12 TLR2 0 0 268 268 1 1
    ATG12 PMAIP1 0 0 335 335 1 1
    ATG12 ATXN3 0 0 241 258 1 1
    ATG12 TOLLIP 0 0 162 202 1 1
    ATG12 LRRK2 0 0 262 278 1 2
    ATG12 TRAF3 0 0 212 238 1 2
    ATG12 TFE3 0 0 223 358 1 1
    ATG12 HSPA5 0 0 425 513 1 2
    ATG12 DNM1 0 0 90 191 1 1
    ATG12 VIPR1 0 0 203 203 1 1
    ATG12 PICALM 0 0 130 202 1 1
    ATG12 SNX2 0 0 45 219 1 1
    ATG12 TBC1D25 0 0 180 202 1 1
    ATG12 MLST8 0 0 329 340 1 2
    ATG12 KRAS 0 0 181 249 1 1
    ATG12 FOXO1 0 0 407 417 1 2
    ATG12 YTHDF1 0 0 0 202 1 1
    ATG12 SOD2 0 0 203 248 1 1
    ATG12 DGKD 0 0 0 256 1 1
    ATG12 FASLG 0 0 184 183 1 1
    ATG12 MON1A 0 0 42 205 1 1
    ATG12 TCEB1 0 0 75 335 1 1
    ATG12 RRAGC 0 0 150 257 1 1
    ATG12 DEPTOR 0 0 293 293 1 1
    ATG12 NOD2 0 800 455 886 1 1
    ATG12 PI4KA 0 0 101 242 1 1
    ATG12 C6orf106 0 0 0 161 1 1
    ATG12 PIK3CD 0 0 0 191 1 1
    ATG12 ATG16L1 958 800 989 999 1 2
    ATG12 JOSD2 0 0 0 318 1 1
    ATG12 UBE2L6 0 0 112 183 1 1
    ATG12 RIPK1 0 0 303 317 1 1
    ATG12 TFB2M 0 0 0 167 1 1
    ATG12 HDAC1 0 0 162 166 1 2
    ATG12 CDKN2A 0 0 210 236 1 2
    ATG12 CASP4 0 0 167 187 1 2
    ATG12 STAMBPL1 0 0 0 157 1 1
    ATG12 GSK3B 0 0 166 207 1 2
    ATG12 NPLOC4 0 0 134 222 1 1
    ATG12 WDR41 0 0 91 150 1 2
    ATG12 CHUK 0 0 256 288 1 1
    ATG12 CUL3 0 0 202 278 1 1
    ATG12 FYTTD1 0 0 0 165 1 1
    ATG12 UBA2 0 0 156 440 1 1
    ATG12 CTSS 0 0 180 217 1 1
    ATG12 TNFRSF10B 0 0 208 222 1 1
    ATG12 CYBB 0 0 263 263 1 1
    ATG12 PPME1 0 0 0 163 1 1
    ATG12 TMEM59L 0 0 81 161 1 1
    ATG12 DIRAS3 0 0 183 184 1 2
    ATG12 UGT2A1 0 0 0 150 1 1
    ATG12 TRIB3 0 0 135 169 1 1
    ATG12 PLD2 0 0 92 161 1 1
    ATG12 UFL1 0 0 75 195 1 1
    ATG12 ATG4D 0 0 565 845 1 2
    ATG12 PSMB6 0 0 81 175 1 1
    ATG12 HSPB8 0 0 186 226 1 2
    ATG12 ATG101 0 0 759 915 1 2
    ATG12 PLEKHM1 0 0 324 323 1 2
    ATG12 NLRP3 0 0 348 347 1 2
    ATG12 DBI 0 0 112 199 1 1
    ATG12 EIF4B 0 0 90 164 1 1
    ATG12 CASP3 0 0 566 606 1 2
    ATG12 SMURF1 0 0 260 276 1 1
    ATG12 PSMB9 0 0 70 166 1 1
    ATG12 EEF1A1 0 0 103 242 1 1
    ATG12 PI4KB 0 0 95 237 1 1
    ATG12 WIPI1 160 0 884 968 1 2
    ATG12 DNM1L 0 0 288 347 1 2
    ATG12 GAPDHS 0 0 389 455 1 1
    ATG12 KIAA0226 0 0 507 528 1 1
    ATG12 GOSR2 0 0 0 159 1 1
    ATG12 PRKAA2 0 0 223 279 1 2
    ATG12 GABARAP 59 900 783 993 1 2
    ATG12 VEGFA 0 0 171 171 1 1
    ATG12 DAK 0 0 234 235 1 1
    ATG12 PTEN 0 0 391 466 1 2
    ATG12 MAPK14 0 0 167 219 1 1
    ATG12 KAT5 0 0 147 167 1 2
    ATG12 UCP1 0 0 150 203 1 1
    ATG12 FAM134B 0 0 322 331 1 1
    ATG12 GOPC 0 0 154 173 1 2
    ATG12 SREBF1 0 0 143 161 1 2
    ATG12 TP53BP2 0 0 233 232 1 1
    ATG12 BAG1 0 0 211 211 1 2
    ATG12 MARK2 0 0 181 181 1 1
    ATG12 BUB3 0 0 0 431 1 1
    ATG12 AMBRA1 0 0 774 793 1 2
    ATG12 NFKBIA 0 0 194 224 1 1
    ATG12 UBE2M 0 0 150 256 1 1
    ATG12 LEP 0 0 142 162 1 1
    ATG12 C12orf5 0 0 204 204 1 1
    ATG12 ENSG00000270386 0 0 0 150 1 1
    ATG12 ANKDD1A 0 0 132 191 1 1
    ATG12 EIF3F 0 0 90 165 1 1
    ATG12 TRIM63 0 0 290 302 1 1
    ATG12 CTSD 0 0 458 482 1 2
    ATG12 ATM 0 0 242 255 1 1
    ATG12 CLCN3 0 0 123 173 1 1
    ATG12 TOMM70A 0 0 170 279 1 1
    ATG12 VTI1B 0 0 304 403 1 2
    ATG12 UBE2S 0 0 235 264 1 1
    ATG12 UGT1A5 0 0 0 150 1 1
    ATG12 UGT1A7 0 0 0 150 1 1
    ATG12 FMN1 0 0 0 545 1 1
    ATG12 PSMB10 0 0 82 205 1 1
    ATG12 IL10 0 0 183 183 1 1
    ATG12 JOSD1 0 0 0 318 1 1
    ATG12 PSMB7 0 0 74 198 1 1
    ATG12 EXOC4 270 0 66 289 1 1
    ATG12 ATG7 733 800 989 999 1 2
    ATG12 SNX30 0 0 0 216 1 1
    ATG12 TRAT1 0 0 201 201 1 1
    ATG12 ACTG1 0 0 210 250 1 1
    ATG12 SPHK2 0 0 95 151 1 1
    ATG12 MAP1LC3B 55 600 827 982 1 2
    ATG12 ISG15 0 0 391 439 1 1
    ATG12 WDFY4 0 0 57 325 1 1
    ATG12 UBC 0 0 140 208 1 1
    ATG12 AGFG1 0 0 267 267 1 1
    ATG12 SPHK1 0 0 123 172 1 2
    ATG12 TSG101 0 0 182 196 1 2
    ATG12 HLA-F 0 0 208 208 1 1
    ATG12 USP30 0 0 183 203 1 1
    ATG12 NECAB3 0 0 96 177 1 1
    ATG12 ATG10 675 800 989 999 1 2
    ATG12 VAMP3 0 0 233 253 1 1
    ATG12 UFC1 0 0 91 202 1 1
    ATG12 HSPB1 0 0 142 178 1 1
    ATG12 IKBKG 0 0 246 261 1 1
    ATG12 PSMD14 0 0 181 413 1 1
    ATG12 MT-CYB 0 0 45 412 1 1
    ATG12 FN1 0 0 155 154 1 1
    ATG12 TBP 0 0 81 233 1 1
    ATG12 AKT3 0 0 54 169 1 1
    ATG12 SEC22B 0 0 147 228 1 1
    ATG12 ADK 0 0 0 248 1 1
    ATG12 DEDD2 0 0 67 448 1 1
    ATG12 STMN1 0 0 156 155 1 1
    ATG12 TBC1D14 0 0 184 214 1 2
    ATG12 STX7 0 0 203 304 1 2
    ATG12 ULK1 0 0 879 941 1 2
    ATG12 BACE1 0 0 137 227 1 1
    ATG12 TRAPPC5 0 0 62 163 1 1
    ATG12 UBQLN2 0 0 175 231 1 2
    ATG12 PSMC5 0 0 0 215 1 1
    ATG12 OPTN 0 0 676 684 1 2
    ATG12 MAP3K5 0 0 212 227 1 1
    ATG12 HMGB1 0 0 293 308 1 2
    ATG12 IFNB1 0 0 373 373 1 1
    ATG12 ESR1 0 0 167 167 1 1
    ATG12 PDIK1L 0 0 0 460 1 1
    ATG12 COPS5 0 0 107 317 1 1
    ATG12 IER2 215 0 0 215 1 1
    ATG12 SMCR8 0 0 95 154 1 2
    ATG12 SIKE1 0 0 123 161 1 1
    ATG12 CTSB 0 0 413 439 1 2
    ATG12 LMNB1 73 0 113 180 1 1
    ATG12 MCL1 270 0 954 965 1 2
    ATG12 ENSG00000100926 0 0 232 280 1 1
    ATG12 SIRT1 0 0 468 523 1 2
    ATG12 XBP1 0 0 409 463 1 2
    ATG12 ATP4A 0 0 213 213 1 1
    ATG12 IRF1 0 0 125 161 1 1
    ATG12 MIB1 0 0 0 375 1 1
    ATG12 UFM1 0 0 505 800 1 1
    ATG12 MT-ND1 0 0 0 175 1 1
    ATG12 YIPF1 0 0 129 188 1 1
    ATG12 ATG5 967 800 990 999 1 2
    ATG12 MTERF3 0 600 0 608 1 1
    ATG12 CALCOCO2 0 0 654 656 1 2
    ATG12 TLR8 0 0 171 171 1 1
    ATG12 WDR18 0 0 162 169 1 1
    ATG12 CASP2 0 0 181 260 1 1
    ATG12 VPS11 0 0 202 231 1 2
    ATG12 KYNU 0 0 48 195 1 1
    ATG12 C22orf29 0 0 367 367 1 1
    ATG12 UGT1A4 0 0 0 150 1 1
    ATG12 TANK 0 0 163 163 1 1
    ATG12 TECPR2 0 0 209 292 1 2
    ATG12 TNF 0 0 341 353 1 1
    ATG12 NBR1 0 0 682 830 1 2
    ATG12 PPP1R15A 0 0 240 241 1 2
    ATG12 ITCH 0 0 134 153 1 1
    ATG12 EEF2 0 0 113 168 1 1
    ATG12 USP14 0 0 148 215 1 1
    ATG12 RNF135 0 600 117 631 1 1
    ATG12 PDCD6IP 0 0 251 368 1 1
    ATG12 WDR45B 0 0 359 610 1 1
    ATG12 UGT1A10 0 0 0 150 1 1
    ATG12 WIPI2 486 600 936 995 1 2
    ATG12 ARIH2 0 0 75 235 1 1
    ATG12 FIS1 0 0 321 404 1 2
    ATG12 UBL3 0 0 63 486 1 1
    ATG12 TRAF3IP3 0 0 81 443 1 1
    ATG12 ATP13A2 0 0 135 170 1 2
    ATG12 FNBP1L 0 0 181 211 1 1
    ATG12 TXNIP 0 0 211 211 1 1
    ATG12 RAB7A 0 0 619 734 1 2
    ATG12 DRAM1 0 0 563 572 1 2
    ATG12 ATG4B 220 0 808 949 1 2
    ATG12 SOS1 0 0 0 189 1 1
    ATG12 EDEM1 0 0 155 166 1 2
    ATG12 GCG 0 0 150 185 1 1
    ATG12 PIK3C2G 0 0 0 191 1 1
    ATG12 PPP1R36 0 0 112 174 1 1
    ATG12 ATP12A 0 0 212 212 1 1
    ATG12 ISCA2 0 0 0 164 1 1
    ATG12 CD63 0 0 161 166 1 1
    ATG12 YTHDF3 0 0 0 202 1 1
    ATG12 TFRC 0 0 151 168 1 1
    ATG12 WDR45 0 0 466 676 1 2
    ATG12 IGF1 0 0 260 260 1 1
    ATG12 MAPK1 0 0 194 205 1 2
    ATG12 IRF7 0 0 217 217 1 1
    ATG12 UVRAG 0 0 754 888 1 2
    ATG12 WDFY3 270 0 635 801 1 2
    ATG12 RAB1B 0 0 108 246 1 2
    ATG12 PKM 0 0 152 151 1 1
    ATG12 GADD45A 0 0 66 164 1 1
    ATG12 PIK3C2B 0 0 46 196 1 1
    ATG12 HSPA9 0 0 103 277 1 1
    ATG12 IRS1 0 0 193 194 1 1
    ATG12 SGK1 0 0 122 201 1 1
    ATG12 SESN1 0 0 246 249 1 2
    ATG12 PFDN1 0 0 53 158 1 1
    ATG12 LIPA 0 0 160 161 1 1
    ATG12 CDK1 0 0 163 163 1 1
    ATG12 EIF4E 0 0 193 212 1 1
    ATG12 STBD1 0 0 160 160 1 2
    ATG12 PRKDC 0 0 0 234 1 2
    ATG12 RPS6KB1 0 0 504 551 1 2
    ATG12 TP53INP2 0 0 213 213 1 2
    ATG12 STX8 0 0 134 378 1 2
    ATG12 RAB33A 0 0 264 322 1 1
    ATG12 ULK3 0 0 295 649 1 2
    ATG12 TRIM65 0 0 82 175 1 1
    ATG12 PRKAA1 0 0 257 310 1 2
    ATG12 TIMD4 0 0 161 161 1 1
    ATG12 CCND1 0 0 317 317 1 1
    ATG12 BCL2L2 0 0 203 203 1 1
    ATG12 UBE2I 0 0 145 228 1 1
    ATG12 EPG5 0 0 369 468 1 2
    ATG12 ATR 0 0 90 233 1 1
    ATG12 NCF1 0 0 86 177 1 1
    ATG12 FAU 0 0 456 519 1 1
    ATG12 BAK1 0 0 241 240 1 2
    ATG12 BCL2 270 0 180 513 1 2
    ATG12 DDIT4 0 0 284 284 1 1
    ATG12 RHEB 0 0 459 572 1 2
    ATG12 TBC1D17 0 0 138 177 1 1
    ATG12 TECPR1 660 0 980 994 1 2
    ATG12 DFFA 0 0 71 214 1 1
    ATG12 PDPK1 0 0 107 245 1 2
    ATG12 CAT 0 0 323 331 1 1
    ATG12 CHMP1A 0 0 90 164 1 1
    ATG12 USP13 0 0 184 183 1 1
    ATG12 CAST 0 0 112 167 1 1
    ATG12 TXN 0 0 142 155 1 1
    ATG12 ATG2A 0 0 517 767 1 2
    ATG12 CANX 0 0 294 416 1 2
    ATG12 SKP1 0 0 163 182 1 1
    ATG12 EIF2S1 0 0 422 448 1 2
    ATG12 MITF 0 0 95 329 1 1
    ATG12 CCZ1 0 0 134 169 1 1
    ATG12 UGT2B11 0 0 0 150 1 1
    ATG12 GOLGA6L2 0 0 0 177 1 1
    ATG12 TBPL2 0 0 0 200 1 1
    ATG12 COG5 0 0 0 160 1 1
    ATG12 LYST 0 0 49 207 1 1
    ATG12 STX17 0 0 618 702 1 2
    ATG12 UBA3 0 0 203 660 1 1
    ATG12 RAB11A 0 0 286 291 1 1
    ATG12 TOMM20 0 0 343 358 1 1
    ATG12 RAC2 0 0 106 161 1 1
    ATG12 ATG2B 0 0 594 804 1 2
    ATG12 TCHP 0 0 253 252 1 1
    ATG12 SEC13 0 0 142 171 1 1
    ATG12 TBK1 0 0 401 441 1 2
    ATG12 HMOX1 0 0 234 234 1 2
    ATG12 NRBF2 0 0 298 298 1 2
    ATG12 RGS19 0 0 158 176 1 2
    ATG12 MLF1 0 0 0 189 1 1
    ATG12 BOLA2-SMG1P6 0 0 0 234 1 1
    ATG12 CDKN1B 0 0 184 183 1 2
    ATG12 PRKCD 0 0 187 187 1 2
    ATG12 ZFYVE1 0 0 751 751 1 2
    ATG12 RIPK3 0 0 234 248 1 1
    ATG12 TSC2 0 0 506 640 1 2
    ATG12 DDB1 0 0 95 173 1 1
    ATG12 PIK3C2A 0 0 57 205 1 2
    ATG12 RBX1 0 0 161 323 1 1
    ATG12 RAB7B 0 0 615 724 1 1
    ATG12 ATP5C1 0 0 0 178 1 1
    ATG12 TRRAP 0 0 0 191 1 1
    ATG12 VDAC1 0 600 320 724 1 2
    ATG12 GMPR2 0 0 0 216 1 1
    ATG12 KLF8 0 0 0 157 1 1
    ATG12 BNIP3L 0 0 635 679 1 2
    ATG12 VAMP7 0 0 320 377 1 1
    ATG12 ABCD3 0 0 207 212 1 1
    ATG12 CDC42 0 0 123 154 1 1
    ATG12 ATG4C 0 0 605 859 1 2
    ATG12 SRC 0 0 240 251 1 1
    ATG12 CHMP7 0 0 57 151 1 1
    ATG12 SCD 0 0 74 179 1 1
    ATG12 STAMBP 0 0 0 157 1 1
    ATG12 ENSG00000250232 0 0 268 556 1 1
    ATG12 EVA1A 0 0 244 243 1 2
    ATG12 FOXO3 0 0 530 596 1 2
    ATG12 SHISA5 0 0 150 188 1 1
    ATG12 EEA1 0 0 310 309 1 1
    ATG12 LRPAP1 0 0 167 167 1 1
    ATG12 S100A6 0 0 384 384 1 1
    ATG12 TOMM40L 0 0 0 162 1 1
    ATG12 EIF2AK3 0 0 459 468 1 2
    ATG12 UGT2B7 0 0 0 150 1 1
    ATG12 UGT2B15 0 0 0 150 1 1
    ATG12 UGT2B4 0 0 0 150 1 1
    ATG12 XPNPEP3 0 0 0 303 1 1
    ATG12 PLSCR1 129 0 691 719 1 1
    ATG12 BNIP1 0 0 180 179 1 2
    ATG12 TLR3 0 0 247 246 1 1
    ATG12 ATG3 972 900 989 999 1 2
    ATG12 DNAJB1 0 0 157 156 1 2
    ATG12 CYLD 0 0 212 213 1 1
    ATG12 PIKFYVE 0 0 288 575 1 1
    ATG12 EIF4EBP1 0 0 401 409 1 1
    ATG12 RNF7 0 0 0 213 1 1
    ATG12 UGT1A9 0 0 0 150 1 1
    ATG12 PTPN23 0 0 0 151 1 1
    ATG12 PEX6 0 0 81 187 1 1
    ATG12 HSP90AB1 0 0 62 164 1 2
    ATG12 FOXO4 0 0 189 189 1 1
    ATG12 TCEB2 0 0 66 178 1 1
    ATG12 VPS37A 0 0 104 225 1 1
    ATG12 UBQLN1 0 0 207 261 1 2
    ATG12 PINK1 0 0 557 653 1 2
    ATG12 BIRC5 0 0 451 495 1 2
    ATG12 CLGN 0 0 0 207 1 1
    ATG12 SIRT4 0 0 233 314 1 1
    ATG12 CCZ1B 0 0 128 163 1 1
    ATG12 BBC3 0 0 195 195 1 1
    ATG12 UBE2E2 0 0 113 175 1 1
    ATG12 VTI1A 0 0 0 177 1 1
    ATG12 NEDD8-MDP1 0 0 0 435 1 1
    ATG12 ERBB2 0 0 202 207 1 2
    ATG12 RNASEH2B 0 0 0 164 1 1
    ATG12 UBA7 0 0 173 580 1 1
    ATG12 PRDX3 0 0 96 235 1 1
    ATG12 IRF3 0 0 325 325 1 1
    ATG12 TLR9 0 0 210 210 1 1
    ATG12 SNX7 0 0 0 216 1 2
    ATG12 UGT1A6 0 0 0 150 1 1
    ATG12 ATF4 0 0 326 338 1 2
    ATG12 CD4 0 0 282 282 1 1
    ATG12 FAS 0 0 180 197 1 2
    ATG12 UBA5 0 0 193 464 1 1
    ATG12 SUMO1 0 0 288 445 1 1
    ATG12 MTMR14 0 0 218 257 1 1
    ATG12 UGT1A1 0 0 0 150 1 1
    ATG12 CAPN1 0 0 248 258 1 2
    ATG12 CTDP1 0 0 0 180 1 1
    ATG12 AKT1 0 0 582 633 1 2
    ATG12 PPARG 0 0 183 183 1 1
    ATG12 TMEM74 0 0 245 244 1 2
    ATG12 VMP1 0 0 558 791 1 2
    ATG12 PARL 0 0 266 275 1 1
    ATG12 ATL2 0 0 45 152 1 1
    ATG12 XIAP 0 0 260 307 1 1
    ATG12 NLRC4 0 0 226 225 1 2
    ATG12 IKBKB 0 0 252 284 1 1
    ATG12 ATF6 0 0 459 492 1 2
    ATG12 ENSG00000279392 0 0 55 153 1 1
    ATG12 DDI1 0 0 45 160 1 1
    ATG12 TSC1 0 0 212 285 1 2
    ATG12 UBA6 0 0 241 623 1 1
    ATG12 BCL2L11 0 0 372 372 1 1
    ATG12 SNX1 0 0 70 239 1 1
    ATG12 ENSG00000173366 0 0 203 203 1 1
    ATG12 DPYSL2 0 0 0 181 1 1
    ATG12 SERPINA1 0 0 144 160 1 2
    ATG12 SLC16A4 0 0 81 177 1 1
    ATG12 AMFR 0 0 145 159 1 1
    ATG12 JUN 0 0 349 353 1 1
    ATG12 ITPR3 0 0 246 264 1 1
    ATG12 TMEM173 0 0 204 204 1 1
    ATG12 DAPK1 0 0 369 393 1 2
    ATG12 YKT6 0 0 194 241 1 1
    ATG12 SNCA 0 0 391 404 1 2
    ATG12 SLC16A3 0 0 67 165 1 1
    ATG12 DNTT 0 0 171 190 1 1
    ATG12 CHEK1 0 0 141 159 1 1
    ATG12 MOCS3 0 0 285 734 1 1
    ATG12 SNAP29 0 0 459 553 1 2
    ATG12 BAG5 0 0 90 187 1 1
    ATG12 GORASP2 0 0 161 161 1 1
    ATG12 DEDD 0 0 108 169 1 1
    ATG12 AKT1S1 0 0 300 340 1 1
    ATG12 CASP1 0 0 363 382 1 2
    ATG12 TNFSF10 0 0 181 181 1 2
    ATG12 PROP1 0 0 0 537 1 1
    ATG12 CAV1 270 0 919 939 1 1
    ATG12 PIK3CG 0 0 180 309 1 1
    ATG12 ULK2 0 0 686 850 1 2
    ATG12 CWF19L1 0 0 0 163 1 1
    ATG12 SLC33A1 0 0 66 223 1 1
    ATG12 EIF2AK2 0 0 134 267 1 2
    ATG12 UGT1A8 0 0 0 150 1 1
    ATG12 EEF1A2 0 0 0 190 1 1
    ATG12 TM2D2 0 0 62 225 1 1
    ATG12 MFN1 0 600 325 735 1 1
    ATG12 FUNDC1 0 600 421 764 1 2
    ATG12 CALR 0 0 234 239 1 1
    ATG12 SAE1 0 0 127 420 1 1
    ATG12 CD8A 0 0 241 240 1 1
    ATG12 RIPK2 0 0 327 337 1 1
    ATG12 TFAM 0 0 218 235 1 1
    ATG12 MON1B 0 0 0 205 1 1
    ATG12 ATP1B3 0 0 48 197 1 1
    ATG12 RASD1 0 0 171 172 1 1
    ATG12 EI24 0 0 218 284 1 2
    ATG12 GOLGA2 0 0 214 214 1 1
    ATG12 GRN 0 0 691 691 1 1
    ATG12 TICAM1 0 0 151 150 1 1
    ATG12 UGT2B17 0 0 0 150 1 1
    ATG12 LAMP2 45 0 609 660 1 2
    ATG12 VCP 0 0 212 278 1 2
    ATG12 CAPN2 0 0 230 240 1 2
    ATG12 SOD1 0 0 210 233 1 1
    ATG12 UBE2F 0 0 101 179 1 1
    ATG12 MIB2 0 0 0 375 1 1
    ATG12 NCOA4 0 0 170 185 1 1
    ATG12 ERN2 0 0 146 183 1 1
    ATG12 RAB1A 0 0 259 346 1 2
    ATG12 MLKL 0 0 213 225 1 1
    ATG12 BCL10 0 0 163 174 1 1
    ATG12 RALB 270 0 247 437 1 1
    ATG12 GABARAPL1 0 900 970 999 1 2
    ATG12 VPS16 0 0 284 348 1 1
    ATG12 SIRT7 0 0 242 278 1 1
    ATG12 SNX8 0 0 0 216 1 1
    ATG12 UBE2L3 0 0 55 153 1 1
    ATG12 HSPA8 0 0 460 493 1 2
    ATG12 PARP1 0 0 230 262 1 2
    ATG12 EIF4G1 0 0 150 184 1 2
    ATG12 CDKN1A 0 0 155 154 1 2
    ATG12 RAB24 0 0 369 407 1 2
    ATG12 ATG9A 0 0 605 902 1 2
    ATG12 UBE2N 0 0 92 152 1 1
    ATG12 BAX 0 0 180 179 1 2
    ATG12 TOMM40 0 0 127 237 1 1
    ATG12 STX6 0 0 61 222 1 1
    ATG12 GBP7 0 0 69 158 1 1
    ATG12 STUB1 0 0 219 219 1 2
    ATG12 NLRX1 0 0 598 598 1 1
    ATG12 ACTB 0 0 519 557 1 1
    ATG12 SNX10 0 0 81 177 1 2
    ATG12 INS 0 0 370 370 1 1
    ATG12 ATG13 0 0 806 929 1 2
    ATG12 AK6 0 0 0 154 1 1
    ATG12 FOXG1 0 0 0 215 1 1
    ATG12 MPND 0 0 0 195 1 1
    ATG12 RNF5 0 0 213 226 1 1
    ATG12 SQSTM1 0 600 837 952 1 2
    ATG12 SLC16A1 0 0 46 543 1 1
    ATG12 BNIP3 0 0 634 735 1 2
    ATG12 MAPK3 0 0 288 298 1 2
    ATG12 SARAF 0 0 0 163 1 1
    ATG12 KEAP1 0 0 323 378 1 2
    ATG12 MYL12B 0 0 0 160 1 1
    ATG12 BRCC3 0 0 0 195 1 1
    ATG12 PROM1 0 0 163 163 1 1
    ATG12 SIRT3 0 0 269 304 1 2
    ATG12 ULK4 0 0 225 226 1 1
    ATG12 NPAT 0 0 413 412 1 1
    ATG12 ITLN2 0 0 60 171 1 1
    ATG12 TFEB 0 0 561 578 1 2
    ATG12 UFD1L 0 0 213 428 1 1
    ATG12 HSP90AA1 0 0 322 383 1 2
    ATG12 PNPLA2 0 0 141 156 1 1
    ATG12 MUL1 0 0 219 244 1 2
    ATG12 PSEN1 0 0 245 244 1 2
    ATG12 UGT1A3 0 0 0 150 1 1
    ATG12 COX4I1 0 0 260 260 1 1
    ATG12 HTRA2 0 0 149 172 1 1
    ATG12 CCL2 0 0 155 154 1 2
    ATG12 CASP8 0 0 592 612 1 2
    ATG12 ALB 0 0 321 374 1 1
    ATG12 ITLN1 0 0 0 179 1 1
    ATG12 PGK1 0 0 171 218 1 2
    ATG12 UBE2U 0 0 0 164 1 1
    ATG12 CUL1 0 0 144 209 1 1
    ATG12 CASP7 0 0 310 389 1 1
    ATG12 ELAVL1 0 0 155 154 1 1
    ATG12 CDK5 0 0 112 175 1 2
    ATG12 LGALS8 0 0 294 294 1 1
    ATG12 EP300 0 0 243 270 1 1
    ATG12 STK35 0 0 0 460 1 1
    ATG12 IL4 0 0 134 157 1 1
    ATG12 PRRC1 0 0 0 163 1 1
    ATG12 AUP1 62 0 194 211 1 1
    ATG12 SH3PXD2B 0 0 0 191 1 1
    ATG12 SMAD3 0 0 125 157 1 1
    ATG12 ANXA8 0 0 182 193 1 1
    ATG12 BIRC3 0 0 96 186 1 1
    ATG12 SEC63 0 0 160 230 1 1
    ATG12 DRAM2 0 0 310 330 1 2
    ATG12 GGH 0 0 166 172 1 1
    ATG12 AIM2 0 0 187 187 1 1
    ATG12 DDX58 270 800 989 998 1 1
    ATG12 RAB9B 0 0 95 352 1 1
    ATG12 SIRT6 0 0 240 276 1 1
    ATG12 PIGM 0 0 0 162 1 1
    ATG12 VPS35 0 0 134 224 1 1
    ATG12 BCL2L13 0 0 245 244 1 1
    ATG12 RMDN1 0 0 0 219 1 1
    ATG12 NCF4 0 0 143 228 1 1
    ATG12 RAP2B 0 0 171 172 1 1
    ATG12 CDH1 0 0 159 158 1 1
    ATG12 MB21D1 0 0 212 212 1 1
    ATG12 EPM2A 0 0 108 233 1 1
    ATG12 SH3PXD2A 0 0 0 191 1 1
    ATG12 TBC1D2 0 0 157 170 1 1
    ATG12 SLC3A2 0 0 71 214 1 1
    ATG12 ATG16L2 0 800 601 952 1 2
    ATG12 BOLA2B 0 0 0 234 1 1
    ATG12 LGALS4 0 0 282 282 1 1
    ATG12 MAP1B 129 0 447 638 1 1
    ATG12 MAP1LC3C 0 900 613 980 1 2
    ATG12 DNM2 0 0 113 211 1 1
    ATG12 MAVS 270 800 965 995 1 1
    ATG12 TRADD 0 0 203 221 1 1
    ATG12 TUFM 0 0 702 858 1 1
    ATG12 VPS18 0 0 235 320 1 1
    ATG12 HIST2H3PS2 0 0 202 214 1 1
    ATG12 DIABLO 0 0 215 215 1 1
    ATG12 IFIH1 270 600 524 848 1 1
    ATG12 SESN2 0 0 280 283 1 2
    ATG12 GMPR 0 0 0 216 1 1
    ATG12 TMEM209 0 0 0 303 1 1
    ATG12 MAP1S 0 0 240 360 1 2
    ATG12 PRNP 0 0 109 160 1 1
    ATG12 VPS52 0 0 57 180 1 1
    ATG12 FKBP1A 0 0 154 178 1 2
    ATG12 PTK2 272 0 241 450 1 1
    ATG12 PEX5 0 0 182 181 1 1
    ATG12 ADIPOQ 0 0 155 154 1 1
    ATG12 MYLPF 0 0 45 245 1 1
    ATG12 TRAPPC10 0 0 90 185 1 1
    ATG12 SKP2 0 0 123 182 1 1
    ATG12 PRKAB1 0 0 193 233 1 2
    ATG12 MAPK8 0 0 450 458 1 2
    ATG12 SUMO3 0 0 0 260 1 1
    ATG12 ZNRD1 0 0 81 198 1 1
    ATG12 MUT 0 0 158 180 1 1
    ATG12 ATP6V0D2 0 0 0 248 1 1
    ATG12 IMPDH1 0 0 0 216 1 1
    ATG12 HLA-DQA1 0 0 209 209 1 1
    ATG12 VPS33A 0 0 170 199 1 1
    ATG12 POMC 0 0 74 171 1 1
    ATG12 TRAF6 0 0 392 493 1 2
    ATG12 TBC1D15 0 0 146 195 1 1
    ATG12 ITPR1 0 0 254 272 1 2
    ATG12 CASP9 0 0 427 461 1 1
    ATG12 ATG4A 0 0 652 873 1 2
    ATG12 TLR7 0 0 293 293 1 1
    ATG12 MYL12A 0 0 0 160 1 1
    ATG12 CYCS 0 0 459 459 1 1
    ATG12 EGF 0 0 206 206 1 1
    ATG12 SH3GLB1 63 0 529 549 1 2
    ATG12 RAB8B 0 0 172 190 1 2
    ATG12 TMEM59 0 0 299 440 1 1
    ATG12 PCSK1 0 0 108 209 1 1
    ATG12 HSPA4 0 0 310 379 1 1
    ATG12 GATA4 0 0 83 150 1 2
    ATG12 UBE4B 0 0 123 158 1 1
    ATG12 ATPAF2 0 0 0 520 1 1
    ATG12 PIK3R1 0 0 109 165 1 1
    ATG12 TRIM5 0 0 160 159 1 2
    ATG12 ZUFSP 0 0 70 246 1 1
    ATG12 TBC1D5 0 0 194 216 1 2
    ATG12 DNPEP 0 0 0 190 1 1
    ATG12 HSP90B1 0 0 211 262 1 1
    ATG12 PSMD4 0 0 181 317 1 1
    ATG12 RPTOR 0 0 459 602 1 2
    ATG12 TBC1D9B 0 0 75 185 1 1
    ATG12 PPARA 0 0 166 165 1 1
    ATG12 IRGC 0 0 146 215 1 1
    ATG12 UBE2H 0 0 74 153 1 1
    ATG12 RNF125 0 0 184 201 1 1
    ATG12 MYC 0 0 440 452 1 2
    ATG12 TM9SF1 0 0 230 278 1 2
    ATG12 IRGM 0 0 601 610 1 2
    ATG12 ELMOD2 0 0 54 204 1 1
    ATG12 UGT2A2 0 0 0 150 1 1
    ATG12 IL18 0 0 298 298 1 1
    ATG12 PARK2 0 0 463 520 1 1
    ATG12 IFNA1 0 0 261 261 1 1
    ATG12 PARP12 0 0 0 189 1 1
    ATG12 TAB2 0 0 140 199 1 1
    ATG12 CAPN3 0 0 57 202 1 1
    ATG12 SDHC 0 0 161 161 1 1
    ATG12 IGF1R 0 0 135 201 1 1
    ATG12 PPARGC1A 0 0 321 321 1 1
    ATG12 UBE2D1 0 0 108 162 1 1
    ATG12 ENSG00000279576 0 0 164 163 1 1
    ATG12 PI3 0 0 393 393 1 1
    ATG12 ENSG00000261832 0 0 218 321 1 1
    ATG12 RICTOR 0 0 296 326 1 2
    ATG12 MEFV 0 0 181 181 1 2
    ATG12 MYLK4 0 0 91 206 1 1
    ATG12 YTHDF2 0 0 0 202 1 1
    ATG12 P4HB 0 0 193 206 1 2
    ATG12 GLIPR2 0 0 194 212 1 2
    ATG12 UBL5 0 0 124 291 1 1
    ATG12 NPC1 0 0 179 180 1 2
    ATG12 PIK3CA 0 0 113 296 1 2
    ATG12 TNFRSF12A 0 0 143 166 1 1
    ATG12 UGT3A1 0 0 0 150 1 1
    ATG12 TBCB 0 0 90 373 1 1
    ATG12 UBA1 0 0 307 648 1 1
    ATG12 PRSS57 0 0 134 153 1 1
    ATG12 CASP10 0 0 156 194 1 1
    ATG12 VPS39 0 0 216 260 1 1
    ATG12 GOLPH3 0 0 204 204 1 1
    ATG12 TAX1BP1 0 0 325 339 1 2
    ATG12 DRG2 0 0 0 159 1 1
    ATG12 PARK7 0 0 180 202 1 1
    ATG12 ANAPC11 0 0 73 156 1 1
    ATG12 UBD 0 0 459 502 1 1
    ATG12 ACTA1 0 0 219 259 1 1
    ATG12 PGAM5 0 0 163 163 1 1
    ATG12 TLR1 0 0 143 156 1 1
    ATG12 NFE2L2 0 0 260 260 1 1
    ATG12 MYL9 0 0 0 160 1 1
    ATG12 RB1CC1 62 0 947 981 1 2
    ATG12 AKT2 0 0 109 218 1 1
    ATG12 UBE2K 0 0 194 229 1 1
    ATG12 STK11 0 0 370 392 1 2
    ATG12 PSMA6 0 0 0 212 1 1
    ATG12 BRCA1 0 0 243 242 1 1
    ATG12 FURIN 0 0 67 283 1 1
    ATG12 BOLA2 0 0 0 234 1 1
    ATG12 MFF 0 0 170 182 1 1
    ATG12 DHX58 0 0 203 203 1 1
    ATG12 OPA1 0 0 134 152 1 1
    ATG12 PPIF 0 0 195 195 1 1
    ATG12 TP53 0 0 502 503 1 2
    ATG12 MDM2 0 0 194 194 1 1
    ATG12 TGM2 0 0 154 161 1 1
    ATG12 TRIM16 0 0 181 181 1 2
    ATG12 DGKH 0 0 0 256 1 1
    ATG12 ENSG00000273637 0 0 0 161 1 1
    ATG12 FADD 270 0 524 675 1 2
    ATG12 ESX1 0 0 202 218 1 1
    ATG12 NEDD8 0 0 459 750 1 1
    ATG12 LAMP1 0 0 601 706 1 2
    ATG12 EGFR 0 0 290 295 1 1
    ATG12 CFLAR 0 0 286 307 1 1
    ATG12 URM1 0 0 556 830 1 1
    ATG12 HTT 270 0 457 676 1 1
    ATG12 MYD88 0 0 263 298 1 1
    ATG12 IRAK1 0 0 113 162 1 1
    ATG12 CAMP 0 0 431 431 1 1
    ATG12 HK2 0 0 152 151 1 1
    ATG12 NLRP4 0 0 320 319 1 1
    ATG12 DDIT3 0 0 391 390 1 2
    ATG12 KPNA3 0 0 54 217 1 1
    ATG12 LIPN 0 0 87 177 1 1
    ATG12 MAP1A 0 0 708 766 1 1
    ATG12 BCAS3 0 0 45 255 1 2
    ATG12 TNFRSF11B 0 0 0 188 1 1
    ATG12 STK36 0 0 147 205 1 1
    ATG12 VPS4B 0 0 180 199 1 1
    ATG12 VAMP8 0 0 423 465 1 2
    ATG12 APAF1 0 0 294 325 1 1
    ATG12 HDAC6 0 0 413 455 1 2
    ATG12 UGT2B28 0 0 0 150 1 1
    ATG12 CAMKK2 0 0 242 247 1 2
    ATG12 CYBA 0 0 122 186 1 1
    ATG12 HGS 0 0 166 223 1 2
    ATG12 CISD2 0 0 208 208 1 2
    ATG12 CHST11 0 0 0 363 1 1
    ATG12 UBE4A 0 0 113 151 1 1
    ATG12 PSMD10 270 0 60 289 1 1
    ATG12 CLYBL 0 0 0 163 1 1
    ATG12 PCSK5 0 0 0 153 1 1
    ATG12 ERN1 0 0 467 490 1 2
    ATG12 IMPDH2 0 0 0 216 1 1
    ATG12 TRIM23 0 0 54 181 1 1
    ATG12 UGT2B10 0 0 0 150 1 1
    ATG12 RAB8A 0 0 151 169 1 2
    ATG12 MCOLN1 0 0 241 266 1 1
    ATG12 NASP 0 0 0 224 1 1
    ATG12 EIF2AK4 0 0 299 328 1 1
    ATG12 RAB9A 0 0 128 375 1 2
    ATG12 STAT3 0 0 286 286 1 2
    ATG12 CD300C 0 0 702 702 1 1
    ATG12 BAG3 0 0 294 299 1 2
    ATG12 TRPM7 0 0 0 168 1 1
    ATG12 RBM18 0 0 0 269 1 1
    ATG12 SIRT5 0 0 242 289 1 1
    ATG12 TRAF5 0 0 95 160 1 1
    ATG12 NEDD4 0 0 181 198 1 2
    ATG12 HIF1A 0 0 341 367 1 2
    ATG12 RAB5B 0 0 93 169 1 1
    ATG12 PSMC2 0 0 66 211 1 1
    ATG12 IL1B 0 0 391 390 1 1
    ATG12 RAB5A 0 0 451 521 1 2
    ATG12 NAE1 0 0 181 493 1 1
    ATG12 SUMO2 0 0 156 348 1 1
    ATG12 CLN3 0 0 246 346 1 2
    ATG12 CXCL8 0 0 181 181 1 1
    ATG12 UGT8 0 0 0 150 1 1
    ATG12 CTSL 0 0 323 354 1 1
    ATG12 MAP1LC3A 0 600 720 972 1 2
    ATG12 HRAS 0 0 210 239 1 1
    ATG12 CTNNB1 0 0 240 239 1 1
    ATG12 SHMT2 0 0 307 307 1 1
    ATG12 EPHA2 0 0 0 156 1 1
    ATG12 MFN2 0 600 391 759 1 2
    ATG12 APP 0 0 297 313 1 1
    ATG12 TRIM13 273 0 74 298 1 2
    ATG12 EXOC8 0 0 193 226 1 1
    ATG12 SNX18 0 0 229 261 1 2
    ATG12 PACS2 0 0 134 266 1 1
    ATG12 CXCR4 0 0 163 163 1 2
    ATG12 NOTCH1 0 0 175 175 1 1
    ATG12 TRAPPC8 0 0 193 252 1 1
    ATG12 MAN2C1 0 0 0 298 1 1
    ATG12 SEC61A1 0 0 134 173 1 1
    ATG12 MTOR 0 0 683 746 1 2
    ATG12 NLRP1 0 0 204 204 1 1
    ATG12 RAD23A 0 0 113 196 1 1
    ATG12 UBL4B 0 0 95 166 1 1
    ATG12 GABRA1 0 0 383 382 1 1
    ATG12 POTEF 0 0 211 273 1 1
    ATG12 PSMC6 0 0 46 212 1 1
    ATG12 C16orf87 0 0 0 187 1 1
    ATG12 MTMR3 0 0 279 288 1 2
    ATG12 MYSM1 0 0 0 195 1 1
    ATG12 UCP2 0 0 175 175 1 1
    ATG12 PIK3C3 0 650 857 981 1 2
    ATG12 SUMO4 0 0 60 274 1 1
    ATG12 CHMP2B 0 0 170 195 1 2
    ATG12 PIRT 0 0 294 295 1 1
    ATG12 CTRL 0 0 234 235 1 1
    ATG12 IL6 0 0 314 313 1 1
    ATG12 BCL2L2-PABPN1 0 0 180 179 1 1
    ATG12 COG6 0 0 136 168 1 1
    ATG12 FOXO6 0 0 181 240 1 1
    ATG12 STAT1 0 0 180 179 1 1
    ATG12 ENDOG 0 0 235 235 1 1
    ATG12 SHMT1 0 0 245 244 1 1
    ATG12 TNFRSF1A 0 0 209 225 1 1
    ATG12 RPS6 0 0 266 282 1 1
    ATG12 UBE2A 0 0 64 227 1 1
    ATG12 PLEK 0 0 205 205 1 1
    ATG12 VPS4A 0 0 142 152 1 1
    ATG12 UGT2A3 0 0 0 150 1 1
    ATG12 NFATC2IP 0 0 46 256 1 1
    ATG12 ARF1 0 0 123 164 1 1
    ATG12 LRSAM1 0 0 242 241 1 2
    ATG12 PSMB1 0 0 54 241 1 1
    ATG12 NSF 0 0 160 228 1 1
    ATG12 BIRC2 0 0 210 261 1 1
    ATG12 IFNG 0 0 193 243 1 2
    ATG12 CCNB1 0 0 162 168 1 1
    ATG12 MAP1LC3B2 0 0 235 806 1 2
    ATG12 UGT3A2 0 0 0 150 1 1
    ATG12 ANXA5 0 0 413 472 1 1
    ATG12 PCSK6 0 0 0 153 1 1
    ATG12 FBXO32 0 0 393 406 1 2
    ATG12 SH3GLB2 0 0 124 155 1 1
    ATG12 SIRT2 0 0 245 281 1 2
    ATG12 ZKSCAN3 0 0 232 231 1 2
    ATG12 SIAH1 0 0 309 309 1 1
    ATG12 UBE2B 0 0 0 210 1 1
    ATG12 HEBP2 0 0 55 151 1 1
    ATG12 TRIM25 0 600 134 638 1 1
    ATG12 PIK3R4 0 650 802 972 1 2
    ATG12 CLEC7A 0 0 170 169 1 1
    ATG12 CASP6 0 0 145 181 1 1
    ATG12 HMGB2 0 0 154 172 1 1
    ATG12 GPBP1 0 0 0 161 1 1
    ATG12 BCL2L1 0 0 520 530 1 2
    ATG12 RELA 0 0 160 177 1 1
    ATG12 RAB33B 0 0 661 717 1 2
    ATG12 TUBB4A 0 0 145 151 1 1
    ATG12 FYCO1 0 0 340 341 1 2
    ATG12 CARM1 0 0 107 152 1 1
    ATG12 TLR4 0 0 302 302 1 1
    ATG12 SMAD2 0 0 137 157 1 1
    ATG12 ENSG00000258466 0 0 0 210 1 1
    ATG12 ATG14 0 650 837 973 1 2
    ATG12 GAPDH 0 0 502 556 1 2
    ATG12 SMG1 0 0 66 254 1 1
    ATG12 GABARAPL2 0 900 976 999 1 2
    ATG12 ABL1 0 0 102 205 1 1
    ATG12 MAP2K7 0 0 207 207 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0019776 Molecular Function Atg8-family ligase activity contributes_to IBA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0031386 Molecular Function protein tag activity enables IBA
    GO:0000045 Biological Process autophagosome assembly involved_in IBA
    GO:0000045 Biological Process autophagosome assembly involved_in ISO
    GO:0000045 Biological Process autophagosome assembly involved_in ISS
    GO:0097352 Biological Process autophagosome maturation involved_in IBA
    GO:0000422 Biological Process autophagy of mitochondrion involved_in IBA
    GO:0061723 Biological Process glycophagy involved_in IBA
    GO:0016236 Biological Process macroautophagy involved_in IMP
    GO:0016236 Biological Process macroautophagy involved_in ISO
    GO:0050687 Biological Process negative regulation of defense response to virus involved_in IDA
    GO:0045824 Biological Process negative regulation of innate immune response involved_in ISO
    GO:0032480 Biological Process negative regulation of type I interferon production involved_in ISO
    GO:0034727 Biological Process piecemeal microautophagy of the nucleus involved_in IBA
    GO:1904973 Biological Process positive regulation of viral translation involved_in IDA
    GO:1901096 Biological Process regulation of autophagosome maturation involved_in IMP
    GO:0034274 Cellular Component Atg12-Atg5-Atg16 complex part_of IBA
    GO:0034274 Cellular Component Atg12-Atg5-Atg16 complex part_of IPI
    GO:0005776 Cellular Component autophagosome located_in IDA
    GO:0000421 Cellular Component autophagosome membrane is_active_in IBA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0030670 Cellular Component phagocytic vesicle membrane located_in TAS
    GO:0034045 Cellular Component phagophore assembly site membrane is_active_in IBA
    GO:0034045 Cellular Component phagophore assembly site membrane located_in ISO
    GO:0034045 Cellular Component phagophore assembly site membrane located_in ISS
    GO:0032991 Cellular Component protein-containing complex part_of NAS
    GO:1990234 Cellular Component transferase complex part_of ISO
    Pathways
    Name DB ID
    Macroautophagy Reactome R-HSA-1632852
    Innate Immune System Reactome R-HSA-168249
    Immune System Reactome R-HSA-168256
    DDX58/IFIH1-mediated induction of interferon-alpha/beta Reactome R-HSA-168928
    Mitophagy Reactome R-HSA-5205647
    PINK1-PRKN Mediated Mitophagy Reactome R-HSA-5205685
    Receptor Mediated Mitophagy Reactome R-HSA-8934903
    Negative regulators of DDX58/IFIH1 signaling Reactome R-HSA-936440
    Autophagy Reactome R-HSA-9612973
    Selective autophagy Reactome R-HSA-9663891
    Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
    Host-pathogen interaction of human coronaviruses - autophagy (WP4863) WikiPathways WP4863_r124639
    Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway (WP4577) WikiPathways WP4577_r123500
    Cytosolic DNA-sensing pathway (WP4655) WikiPathways WP4655_r123496
    Nanoparticle triggered autophagic cell death (WP2509) WikiPathways WP2509_r101755
    Autophagy (WP4923) WikiPathways WP4923_r110416
    Novel intracellular components of RIG-I-like receptor pathway (WP3865) WikiPathways WP3865_r123636
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_033363 2 miscRNA transcript variant 3 NC_000005 Reference
    NR_033362 2 miscRNA transcript variant 2 NC_000005 Reference
    NR_073603 2 miscRNA transcript variant 4 NC_000005 Reference
    NM_001277783 2 mRNA transcript variant 5 NC_000005 Reference
    NM_004707 4 mRNA transcript variant 1 NC_000005 Reference