TNFSF10

TNF superfamily member 10
General Information
Name TNF superfamily member 10
Alias
  • tumor necrosis factor ligand superfamily member 10
  • Apo-2 ligand
  • TNF-related apoptosis inducing ligand TRAIL
  • chemokine tumor necrosis factor ligand superfamily member 10
  • tumor necrosis factor (ligand) family, member 10
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand 6A
  • tumor necrosis factor superfamily member 10
Synonyms TRAIL Apo-2L TL2 CD253 APO2L TNLG6A
Gene_family CD molecules|Tumor necrosis factor superfamily
organism Homo sapiens
entrez_id 8743
location 3q26
transcript_count 4
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
      Stringdb Tumor necrosis factor ligand superfamily member 10; Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis; CD molecules
      nextProt Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    TNFSF10 BioGRID CFTR GeneID BioGRID PCA
    TNFSF10 BioGRID RBM42 GeneID BioGRID Affinity Capture-MS
    TNFSF10 BioGRID CCZ1 GeneID BioGRID Affinity Capture-MS
    TNFSF10 BioGRID RMC1 GeneID BioGRID Affinity Capture-MS
    TNFSF10 BioGRID NOMO1 GeneID BioGRID Affinity Capture-MS
    TNFSF10 BioGRID TNFRSF10B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
    TNFSF10 BioGRID FADD GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID CASP8 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID CFLAR GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID RIPK1 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID PEA15 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID CUL3 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID PPP2CA GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID ZDHHC17 GeneID BioGRID Two-hybrid
    TNFSF10 BioGRID CASP3 GeneID BioGRID Biochemical Activity
    TNFSF10 BioGRID TRAF2 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID TNFAIP3 GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID SOCS3 GeneID BioGRID Affinity Capture-Western
    TNFSF10 Protein RBM48 GeneID HPRD None
    TNFSF10 Protein TNFRSF10D GeneID HPRD None
    TNFSF10 Protein TNFRSF10C GeneID HPRD None
    TNFSF10 Protein TNFRSF10B GeneID HPRD None
    TNFSF10 Protein TNFRSF10A GeneID HPRD None
    TNFSF10 Protein TNFSF10 GeneID HPRD None
    TNFSF10 Protein TNFRSF11B GeneID HPRD None
    TNFSF10 Protein ACP5 GeneID HPRD None
    TNFSF10 BioGRID TNFRSF10A GeneID BioGRID Affinity Capture-Western
    TNFSF10 BioGRID TNFRSF10D GeneID BioGRID Reconstituted Complex
    TNFSF10 BioGRID TNFSF10 GeneID BioGRID Co-crystal Structure
    TNFSF10 BioGRID RBM48 GeneID BioGRID Two-hybrid
    TNFSF10 BioGRID ACP5 GeneID BioGRID Two-hybrid
    TNFSF10 Protein IER3 GeneID BIND An unspecified isoform of IEX-1 interacts with TNFSF10.
    TNFSF10 Protein TNFRSF10B GeneID BIND TNFSF10 (TRAIL) interacts with TNFRSF10B (DR5).
    TNFSF10 Nucleotide None None BIND RNA Pol II interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide CREBBP GeneID BIND CBP interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide SP3 GeneID BIND SP3 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide SP1 GeneID BIND SP1 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide HDAC5 GeneID BIND An unspecifed isoform of HDAC5 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide HDAC4 GeneID BIND HDAC4 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide HDAC3 GeneID BIND HDAC3 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide HDAC2 GeneID BIND HDAC2 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide HDAC1 GeneID BIND HDAC1 interacts with the TNFSF10 promoter.
    TNFSF10 Nucleotide H3-4 GeneID BIND Acetylated H3 interacts with the TNFSF10 promoter.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    TNFSF10 IL10RB 0 0 143 178 1 1
    TNFSF10 ECI1 0 0 0 351 1 1
    TNFSF10 SIRT1 0 0 211 211 1 2
    TNFSF10 EOMES 0 0 267 267 1 1
    TNFSF10 MCL1 0 0 594 594 1 2
    TNFSF10 ERVW-1 0 0 413 413 1 1
    TNFSF10 CTSB 0 0 240 239 1 2
    TNFSF10 SPI1 0 0 170 241 1 1
    TNFSF10 CST7 0 0 66 187 1 1
    TNFSF10 LYN 0 0 140 173 1 1
    TNFSF10 UBE2D2 0 0 0 185 1 1
    TNFSF10 CTSK 0 0 167 167 1 1
    TNFSF10 IRF5 0 0 205 234 1 1
    TNFSF10 HMGB1 0 0 310 309 1 2
    TNFSF10 IFNB1 0 0 619 619 1 1
    TNFSF10 ESR1 0 0 290 290 1 1
    TNFSF10 ACKR2 0 0 202 202 1 1
    TNFSF10 MAP3K5 0 0 324 349 1 1
    TNFSF10 IP6K2 0 0 296 296 1 1
    TNFSF10 ITGAM 0 0 358 398 1 1
    TNFSF10 PDCD1 0 0 261 269 1 1
    TNFSF10 TLR8 0 0 290 362 1 1
    TNFSF10 BCL2L14 0 0 154 153 1 1
    TNFSF10 ITGB3 0 0 112 207 1 1
    TNFSF10 CAMTA2 0 0 0 522 1 1
    TNFSF10 EDAR 0 0 181 181 1 1
    TNFSF10 ATG5 0 0 252 252 1 2
    TNFSF10 MAP2K6 0 0 143 162 1 1
    TNFSF10 C1QA 0 0 53 213 1 1
    TNFSF10 SAMD9 0 0 0 216 1 1
    TNFSF10 BAHCC1 0 0 0 254 1 1
    TNFSF10 HLA-C 0 0 211 239 1 1
    TNFSF10 IRF1 0 0 395 462 1 1
    TNFSF10 TNFAIP2 0 0 71 153 1 1
    TNFSF10 CXCR3 0 0 286 320 1 1
    TNFSF10 STAT2 0 0 324 381 1 1
    TNFSF10 XBP1 0 0 159 158 1 2
    TNFSF10 ENSG00000255819 0 0 517 544 1 1
    TNFSF10 HSPB1 0 0 181 181 1 1
    TNFSF10 WISP3 0 0 53 150 1 1
    TNFSF10 HSPB2 0 0 171 171 1 1
    TNFSF10 TERT 0 0 243 242 1 1
    TNFSF10 GBP3 0 0 74 188 1 1
    TNFSF10 S100A4 0 0 193 213 1 1
    TNFSF10 USP18 0 0 193 285 1 1
    TNFSF10 TGFBR1 0 0 150 203 1 1
    TNFSF10 NFKBIB 0 0 134 166 1 1
    TNFSF10 ADAM17 0 0 241 240 1 1
    TNFSF10 XCL1 0 0 155 173 1 1
    TNFSF10 LY6E 0 0 174 252 1 1
    TNFSF10 ISG15 0 0 340 396 1 1
    TNFSF10 SERPINB5 0 0 165 171 1 1
    TNFSF10 DFFB 0 0 310 309 1 1
    TNFSF10 TIMP2 0 0 163 163 1 1
    TNFSF10 MAP1LC3B 0 0 139 155 1 2
    TNFSF10 TBX21 0 0 320 345 1 1
    TNFSF10 ULK1 0 0 143 189 1 2
    TNFSF10 NCAM1 0 0 390 390 1 1
    TNFSF10 RPS6KA1 0 0 112 237 1 1
    TNFSF10 MAP3K12 0 0 155 154 1 1
    TNFSF10 NUCB1 0 0 0 217 1 1
    TNFSF10 DEDD2 0 0 181 181 1 1
    TNFSF10 MMP13 0 0 202 202 1 1
    TNFSF10 C3 0 0 120 153 1 1
    TNFSF10 PDCD2L 0 0 61 384 1 1
    TNFSF10 MT-CYB 0 0 142 167 1 1
    TNFSF10 FN1 0 0 301 301 1 1
    TNFSF10 C1QC 0 0 90 247 1 1
    TNFSF10 MT-CO1 0 0 380 380 1 1
    TNFSF10 KLRC2 0 0 282 282 1 1
    TNFSF10 CCR9 0 0 150 169 1 1
    TNFSF10 IKBKG 0 900 321 929 1 1
    TNFSF10 CCR7 0 0 324 356 1 1
    TNFSF10 ATM 0 0 267 267 1 1
    TNFSF10 THBD 0 0 181 204 1 1
    TNFSF10 S1PR5 0 0 123 158 1 1
    TNFSF10 IGF2 0 0 171 171 1 1
    TNFSF10 TNFRSF10C 698 900 806 996 1 1
    TNFSF10 CTSD 0 0 235 235 1 2
    TNFSF10 FCGR3B 0 0 391 420 1 1
    TNFSF10 CCL22 0 0 214 258 1 1
    TNFSF10 CTSG 0 0 108 150 1 1
    TNFSF10 CCL3 0 0 402 434 1 1
    TNFSF10 HLA-A 0 0 194 223 1 1
    TNFSF10 GDF15 0 0 163 169 1 1
    TNFSF10 SP110 0 0 0 327 1 1
    TNFSF10 CMPK2 0 0 108 252 1 1
    TNFSF10 GIMAP7 0 0 91 254 1 1
    TNFSF10 CCL23 0 0 134 179 1 1
    TNFSF10 ACTG1 0 0 167 167 1 1
    TNFSF10 TGFBR2 0 0 193 227 1 1
    TNFSF10 RXRG 0 0 53 199 1 1
    TNFSF10 SELE 0 0 371 385 1 1
    TNFSF10 PAPLN 0 0 73 216 1 1
    TNFSF10 ATG7 0 0 249 248 1 2
    TNFSF10 PARVG 0 0 108 167 1 1
    TNFSF10 FLT3 0 0 217 217 1 1
    TNFSF10 NAMPT 0 0 150 177 1 1
    TNFSF10 CXCL2 0 0 261 282 1 1
    TNFSF10 DAPK2 0 0 211 229 1 2
    TNFSF10 CNTLN 0 0 0 189 1 1
    TNFSF10 MON2 0 0 0 196 1 1
    TNFSF10 STRADB 0 0 351 351 1 1
    TNFSF10 IRAK4 0 0 122 174 1 1
    TNFSF10 CXCR6 0 0 258 286 1 1
    TNFSF10 SNAI1 0 0 195 195 1 1
    TNFSF10 IL10 0 0 509 509 1 1
    TNFSF10 CCL20 0 0 341 352 1 1
    TNFSF10 PTEN 0 0 406 406 1 2
    TNFSF10 VEGFA 0 0 470 470 1 1
    TNFSF10 IFNA21 0 0 167 167 1 1
    TNFSF10 IRF4 0 0 150 178 1 1
    TNFSF10 TRAFD1 0 0 175 231 1 1
    TNFSF10 TNFRSF11A 0 0 337 527 1 1
    TNFSF10 GLIPR1 0 0 442 442 1 1
    TNFSF10 BST2 0 0 190 230 1 1
    TNFSF10 MTA2 0 0 0 188 1 1
    TNFSF10 NFATC1 0 0 166 188 1 1
    TNFSF10 PDCD1LG2 0 0 229 245 1 1
    TNFSF10 TRAF7 0 0 174 173 1 1
    TNFSF10 TMEM86A 0 0 74 326 1 1
    TNFSF10 CASP5 0 0 285 369 1 1
    TNFSF10 BHLHE41 0 0 0 190 1 1
    TNFSF10 FCER1G 0 0 124 189 1 1
    TNFSF10 PARP16 0 0 0 189 1 1
    TNFSF10 KIT 0 0 261 261 1 1
    TNFSF10 NFKBIA 0 0 422 438 1 1
    TNFSF10 FERMT3 0 0 0 318 1 1
    TNFSF10 LEP 0 0 213 213 1 1
    TNFSF10 ZNF37A 0 0 61 159 1 1
    TNFSF10 SYK 0 0 171 221 1 1
    TNFSF10 BAG1 0 0 181 181 1 2
    TNFSF10 NGFR 0 0 209 209 1 1
    TNFSF10 FCGR2A 0 0 210 238 1 1
    TNFSF10 TNFRSF9 0 0 405 433 1 1
    TNFSF10 IL21R 0 0 142 191 1 1
    TNFSF10 RORC 0 0 108 321 1 1
    TNFSF10 CLEC4E 0 0 134 187 1 1
    TNFSF10 CSF3R 0 0 101 177 1 1
    TNFSF10 MAPK14 0 0 240 287 1 1
    TNFSF10 TIMP3 0 0 210 210 1 1
    TNFSF10 CD226 0 0 342 342 1 1
    TNFSF10 CXCL5 0 0 230 229 1 1
    TNFSF10 VEGFC 0 0 148 304 1 1
    TNFSF10 CYBB 0 0 170 228 1 1
    TNFSF10 USP48 0 0 142 170 1 1
    TNFSF10 CD28 0 0 324 323 1 1
    TNFSF10 CD5 0 0 181 220 1 1
    TNFSF10 TRIM22 0 0 108 369 1 1
    TNFSF10 ATG12 0 0 181 181 1 2
    TNFSF10 DDX60L 0 0 0 154 1 1
    TNFSF10 TNFRSF10B 982 900 988 999 1 1
    TNFSF10 IL13 0 0 392 392 1 1
    TNFSF10 CTSS 0 0 154 342 1 1
    TNFSF10 TNFSF13B 0 0 390 452 1 1
    TNFSF10 ALOX5 0 0 151 215 1 1
    TNFSF10 BCAR1 0 0 81 161 1 1
    TNFSF10 PSMB9 0 0 181 286 1 1
    TNFSF10 CCL11 0 0 310 309 1 1
    TNFSF10 CYP26A1 0 0 90 286 1 1
    TNFSF10 PTGS2 0 0 390 403 1 1
    TNFSF10 NKG7 0 0 108 179 1 1
    TNFSF10 F3 0 0 179 179 1 1
    TNFSF10 ERBB3 0 0 166 165 1 1
    TNFSF10 CASP3 270 900 681 974 1 2
    TNFSF10 FCN2 0 0 0 190 1 1
    TNFSF10 WFIKKN2 0 0 67 425 1 1
    TNFSF10 DAXX 0 0 232 231 1 1
    TNFSF10 TNFRSF21 0 0 506 536 1 1
    TNFSF10 REL 0 0 261 261 1 1
    TNFSF10 NLRP3 0 0 241 275 1 2
    TNFSF10 KIR2DL1 0 0 283 282 1 1
    TNFSF10 BRCA2 0 0 119 176 1 1
    TNFSF10 CARD16 0 0 0 160 1 1
    TNFSF10 MMP14 0 0 167 167 1 1
    TNFSF10 CD99 0 0 292 292 1 1
    TNFSF10 IL33 0 0 236 253 1 1
    TNFSF10 CXCL1 0 0 390 405 1 1
    TNFSF10 TRPM2 0 0 74 158 1 1
    TNFSF10 ATG4D 0 0 113 168 1 2
    TNFSF10 TRIB3 0 0 329 329 1 1
    TNFSF10 PLD2 0 0 0 258 1 1
    TNFSF10 HDAC1 0 0 205 205 1 2
    TNFSF10 CSF1 0 0 319 319 1 1
    TNFSF10 DTX3L 0 0 74 160 1 1
    TNFSF10 ULBP1 0 0 212 212 1 1
    TNFSF10 RIPK1 486 900 557 975 1 1
    TNFSF10 LTBR 0 0 260 294 1 1
    TNFSF10 BRF2 0 0 0 252 1 1
    TNFSF10 ATG16L1 0 0 139 175 1 2
    TNFSF10 CEBPB 0 0 163 163 1 1
    TNFSF10 UBE2L6 0 0 123 223 1 1
    TNFSF10 SMPD1 0 900 167 913 1 1
    TNFSF10 IL13RA1 0 0 207 261 1 1
    TNFSF10 MT-CO2 0 0 194 194 1 1
    TNFSF10 NOD2 0 0 208 295 1 1
    TNFSF10 CIITA 0 0 112 162 1 1
    TNFSF10 CUL3 486 0 125 531 1 1
    TNFSF10 CHUK 0 900 310 931 1 1
    TNFSF10 KLF2 0 0 127 204 1 1
    TNFSF10 S100A12 0 0 142 184 1 1
    TNFSF10 DUSP2 0 0 75 167 1 1
    TNFSF10 CALHM2 0 0 122 186 1 1
    TNFSF10 EPSTI1 0 0 91 199 1 1
    TNFSF10 CAMLG 0 0 134 152 1 1
    TNFSF10 ITGAX 0 0 310 344 1 1
    TNFSF10 GSK3B 0 0 151 176 1 2
    TNFSF10 MRC1 0 0 181 210 1 1
    TNFSF10 CXCL16 0 0 193 222 1 1
    TNFSF10 CDKN2A 0 0 283 282 1 2
    TNFSF10 CASP4 0 0 392 458 1 2
    TNFSF10 BMPR1B 0 0 0 188 1 1
    TNFSF10 SOCS2 0 0 193 193 1 1
    TNFSF10 GUSB 0 0 134 194 1 1
    TNFSF10 HLA-B 0 0 142 192 1 1
    TNFSF10 CCL17 0 0 181 287 1 1
    TNFSF10 IFNGR1 0 0 222 309 1 1
    TNFSF10 SOD2 0 0 143 181 1 1
    TNFSF10 CD3E 0 0 134 173 1 1
    TNFSF10 KRAS 0 0 287 337 1 1
    TNFSF10 FOXO1 0 0 218 218 1 2
    TNFSF10 LILRB4 0 0 118 151 1 1
    TNFSF10 ITGB2 0 0 181 537 1 1
    TNFSF10 CSRNP1 0 0 47 193 1 1
    TNFSF10 CCL8 0 0 289 332 1 1
    TNFSF10 HSPA5 0 0 261 261 1 2
    TNFSF10 CD96 0 0 140 171 1 1
    TNFSF10 CASP14 0 0 260 293 1 1
    TNFSF10 GBP6 0 0 94 203 1 1
    TNFSF10 IRAK3 0 0 108 151 1 1
    TNFSF10 TNIP1 0 0 108 263 1 1
    TNFSF10 TIFA 0 0 145 220 1 1
    TNFSF10 XAF1 0 0 465 628 1 1
    TNFSF10 BIRC7 0 0 322 321 1 1
    TNFSF10 STAT5A 0 0 260 302 1 1
    TNFSF10 ANGPTL4 0 0 146 178 1 1
    TNFSF10 IGSF6 0 0 85 182 1 1
    TNFSF10 MNDA 0 0 50 150 1 1
    TNFSF10 PPP1R3F 0 0 82 175 1 1
    TNFSF10 IL15RA 0 0 253 307 1 1
    TNFSF10 GALNT14 0 0 280 280 1 1
    TNFSF10 SCNN1A 0 0 91 226 1 1
    TNFSF10 SOCS3 270 0 261 437 1 1
    TNFSF10 S100A8 0 0 91 187 1 1
    TNFSF10 TBC1D2B 0 0 102 176 1 1
    TNFSF10 CCL27 0 0 325 325 1 1
    TNFSF10 FOS 0 0 286 286 1 1
    TNFSF10 GHSR 0 0 0 302 1 1
    TNFSF10 FASLG 0 600 801 730 1 1
    TNFSF10 HLA-DRA 0 0 112 240 1 1
    TNFSF10 NOD1 0 0 193 210 1 1
    TNFSF10 IFNA17 0 0 165 165 1 1
    TNFSF10 PGF 0 0 158 157 1 1
    TNFSF10 CD72 0 0 125 179 1 1
    TNFSF10 SHARPIN 0 0 162 161 1 1
    TNFSF10 CD81 0 0 168 167 1 1
    TNFSF10 CFB 0 0 150 238 1 1
    TNFSF10 PFKFB1 0 0 66 165 1 1
    TNFSF10 FCN1 0 0 0 219 1 1
    TNFSF10 CD86 0 0 403 462 1 1
    TNFSF10 IL18R1 0 0 177 214 1 1
    TNFSF10 TRAF3 0 0 291 290 1 2
    TNFSF10 MET 0 0 203 203 1 1
    TNFSF10 CDKN2C 0 0 97 197 1 1
    TNFSF10 HSH2D 0 0 170 210 1 1
    TNFSF10 CDKN2B 0 0 95 241 1 1
    TNFSF10 PIK3CB 0 900 81 906 1 1
    TNFSF10 TLR2 0 0 503 574 1 1
    TNFSF10 PMAIP1 0 0 497 497 1 1
    TNFSF10 PNPLA4 0 0 0 248 1 1
    TNFSF10 DUSP1 0 0 153 152 1 1
    TNFSF10 PEA15 270 0 267 442 1 1
    TNFSF10 USP49 0 0 53 198 1 1
    TNFSF10 ANXA1 0 0 175 217 1 1
    TNFSF10 ITGA2 0 0 122 201 1 1
    TNFSF10 IL2 0 0 517 517 1 1
    TNFSF10 TLR6 0 0 260 281 1 1
    TNFSF10 SDC1 0 0 211 211 1 1
    TNFSF10 ABCB1 0 0 209 218 1 1
    TNFSF10 THBS1 0 0 207 226 1 1
    TNFSF10 PTGES 0 0 123 160 1 1
    TNFSF10 HLA-DPA1 0 0 123 257 1 1
    TNFSF10 BECN1 0 0 323 323 1 2
    TNFSF10 CCL7 0 0 336 354 1 1
    TNFSF10 PPARG 0 0 265 265 1 1
    TNFSF10 ANKUB1 0 0 103 170 1 1
    TNFSF10 TGFB2 0 0 181 199 1 1
    TNFSF10 GBP2 0 0 217 466 1 1
    TNFSF10 AKT1 0 0 556 556 1 2
    TNFSF10 CD48 0 0 218 300 1 1
    TNFSF10 ACKR1 0 0 174 173 1 1
    TNFSF10 PARP4 0 0 92 177 1 1
    TNFSF10 LY96 0 0 170 220 1 1
    TNFSF10 CSF2 0 0 460 459 1 1
    TNFSF10 IL12RB1 0 0 170 277 1 1
    TNFSF10 FAS 0 600 710 883 1 2
    TNFSF10 CARD8 0 0 135 160 1 1
    TNFSF10 PTHLH 0 0 151 152 1 1
    TNFSF10 IFIT3 0 0 294 517 1 1
    TNFSF10 VCAM1 0 0 308 323 1 1
    TNFSF10 CD4 0 0 589 613 1 1
    TNFSF10 COL4A2 0 0 96 151 1 1
    TNFSF10 ACACB 0 0 0 185 1 1
    TNFSF10 CD247 0 0 241 273 1 1
    TNFSF10 KLF4 0 0 125 234 1 1
    TNFSF10 APOL3 0 0 90 263 1 1
    TNFSF10 NLRC4 0 0 152 184 1 2
    TNFSF10 IKBKB 0 900 297 929 1 1
    TNFSF10 SKI 0 0 0 321 1 1
    TNFSF10 ALOX5AP 0 0 0 168 1 1
    TNFSF10 ATF6 0 0 150 203 1 2
    TNFSF10 ESM1 0 0 90 201 1 1
    TNFSF10 KIR2DL3 0 0 266 266 1 1
    TNFSF10 IFNLR1 0 0 159 158 1 1
    TNFSF10 GALNT6 0 0 108 173 1 1
    TNFSF10 CFH 0 0 81 171 1 1
    TNFSF10 CLEC4C 0 0 233 232 1 1
    TNFSF10 RUNX2 0 0 150 151 1 1
    TNFSF10 SPTB 0 0 202 202 1 1
    TNFSF10 TMEM74 0 0 141 194 1 2
    TNFSF10 XIAP 0 0 661 675 1 1
    TNFSF10 IL11 0 0 211 211 1 1
    TNFSF10 TMEM86B 0 0 0 189 1 1
    TNFSF10 BMP8B 0 0 67 160 1 1
    TNFSF10 CCNG2 0 0 155 154 1 1
    TNFSF10 GPT 0 0 241 263 1 1
    TNFSF10 ID2 0 0 149 235 1 1
    TNFSF10 USP3 0 0 54 223 1 1
    TNFSF10 BIRC5 0 0 229 228 1 2
    TNFSF10 ITGB6 0 0 71 158 1 1
    TNFSF10 CD58 0 0 167 185 1 1
    TNFSF10 IL24 0 0 252 270 1 2
    TNFSF10 LRRC3B 0 0 53 166 1 1
    TNFSF10 PUS10 0 0 641 641 1 1
    TNFSF10 IFNGR2 0 0 202 219 1 1
    TNFSF10 BCL6 0 0 181 181 1 1
    TNFSF10 HSP90AB1 0 0 96 187 1 2
    TNFSF10 AXL 0 0 207 207 1 1
    TNFSF10 LGALS9B 0 0 45 206 1 1
    TNFSF10 P4HA3 0 0 0 303 1 1
    TNFSF10 CXCL10 0 0 508 599 1 1
    TNFSF10 BIRC8 0 0 286 316 1 1
    TNFSF10 CYLD 0 0 243 242 1 1
    TNFSF10 KRT18 0 0 193 193 1 1
    TNFSF10 AIFM1 0 0 123 320 1 1
    TNFSF10 SQRDL 0 0 0 165 1 1
    TNFSF10 PYCARD 0 0 218 268 1 1
    TNFSF10 MAP3K1 0 900 184 914 1 1
    TNFSF10 CD1D 0 0 253 271 1 1
    TNFSF10 KIR2DL4 0 0 177 201 1 1
    TNFSF10 MEDAG 0 0 57 355 1 1
    TNFSF10 TNFSF8 0 0 406 461 1 1
    TNFSF10 CARD6 0 0 124 163 1 1
    TNFSF10 GZMK 0 0 142 201 1 1
    TNFSF10 TLR9 0 0 401 400 1 1
    TNFSF10 FBN1 0 0 60 158 1 1
    TNFSF10 IRF3 0 0 321 321 1 1
    TNFSF10 ARG2 0 0 181 181 1 1
    TNFSF10 ERBB2 0 0 391 390 1 2
    TNFSF10 CD34 0 0 292 318 1 1
    TNFSF10 NGF 0 0 269 269 1 1
    TNFSF10 UBA7 0 0 74 166 1 1
    TNFSF10 BBC3 0 0 374 374 1 1
    TNFSF10 CTSC 0 0 115 205 1 1
    TNFSF10 TNFSF11 0 0 566 205 1 1
    TNFSF10 DGAT2 0 0 46 204 1 1
    TNFSF10 CD47 0 0 243 275 1 1
    TNFSF10 FOXO3 270 0 336 494 1 2
    TNFSF10 APOE 0 0 166 165 1 1
    TNFSF10 IRF8 0 0 142 198 1 1
    TNFSF10 SAMD9L 0 0 118 573 1 1
    TNFSF10 DAP3 0 900 453 943 1 1
    TNFSF10 SRC 0 0 339 339 1 1
    TNFSF10 ATG4C 0 0 112 167 1 2
    TNFSF10 DOCK2 0 0 0 235 1 1
    TNFSF10 MIF 0 0 234 234 1 1
    TNFSF10 LGALS3 0 0 357 386 1 1
    TNFSF10 ATG3 0 0 209 210 1 2
    TNFSF10 PARP9 0 0 123 351 1 1
    TNFSF10 RSAD2 0 0 325 509 1 1
    TNFSF10 PLSCR1 0 0 251 328 1 1
    TNFSF10 IL19 0 0 123 161 1 1
    TNFSF10 BIRC6 0 0 206 206 1 1
    TNFSF10 BNIP1 0 0 234 313 1 2
    TNFSF10 CDKN3 0 0 209 209 1 1
    TNFSF10 TLR3 0 0 459 471 1 1
    TNFSF10 FLT1 0 0 206 206 1 1
    TNFSF10 TNFRSF18 0 0 216 217 1 1
    TNFSF10 CADM1 0 0 150 300 1 1
    TNFSF10 CD52 0 0 141 192 1 1
    TNFSF10 EIF2AK3 0 0 257 274 1 2
    TNFSF10 CCR8 0 0 113 310 1 1
    TNFSF10 TNFSF12 0 0 601 601 1 1
    TNFSF10 TP53INP1 0 0 57 150 1 2
    TNFSF10 ACLY 0 0 54 249 1 1
    TNFSF10 STAT6 0 0 195 239 1 1
    TNFSF10 IL32 0 0 193 244 1 1
    TNFSF10 PTPN6 0 0 112 155 1 1
    TNFSF10 HMOX1 0 0 193 193 1 2
    TNFSF10 FOXP3 0 0 353 353 1 1
    TNFSF10 ARHGAP32 0 0 0 250 1 1
    TNFSF10 NCR2 0 0 390 403 1 1
    TNFSF10 TCHP 0 0 264 264 1 1
    TNFSF10 TBK1 0 0 150 298 1 2
    TNFSF10 KLRB1 0 0 184 241 1 1
    TNFSF10 LRRC71 0 0 91 162 1 1
    TNFSF10 NFATC2 0 0 134 163 1 1
    TNFSF10 JAK1 0 0 235 235 1 1
    TNFSF10 KDR 0 0 235 235 1 2
    TNFSF10 RASSF1 0 0 151 150 1 1
    TNFSF10 MMP12 0 0 193 218 1 1
    TNFSF10 ANPEP 0 0 103 153 1 1
    TNFSF10 CLDN4 0 0 59 160 1 1
    TNFSF10 EIF2S1 0 0 210 210 1 2
    TNFSF10 ICOS 0 0 96 152 1 1
    TNFSF10 PF4 0 0 155 179 1 1
    TNFSF10 MGAT5 0 0 296 296 1 1
    TNFSF10 F2R 0 0 134 152 1 1
    TNFSF10 SCGB1A1 0 0 48 150 1 1
    TNFSF10 BNIP3L 0 0 194 208 1 2
    TNFSF10 C1QB 0 0 100 294 1 1
    TNFSF10 TGFB1 0 0 212 244 1 1
    TNFSF10 GADD45G 0 0 150 203 1 1
    TNFSF10 VDAC1 0 0 161 161 1 2
    TNFSF10 BTN3A3 0 0 95 187 1 1
    TNFSF10 SLC25A42 0 0 57 335 1 1
    TNFSF10 LGALS9C 0 0 0 210 1 1
    TNFSF10 STAT5B 0 0 232 248 1 1
    TNFSF10 IFIT1 0 0 376 507 1 1
    TNFSF10 MMP10 0 0 117 172 1 1
    TNFSF10 RIPK3 0 900 460 950 1 1
    TNFSF10 PARP10 0 0 74 157 1 1
    TNFSF10 CDKN1B 0 0 274 280 1 2
    TNFSF10 PRKCD 0 0 161 179 1 2
    TNFSF10 CD2 0 0 181 356 1 1
    TNFSF10 CCL19 0 0 234 278 1 1
    TNFSF10 DFFA 0 0 322 321 1 1
    TNFSF10 EFNA1 0 0 126 251 1 1
    TNFSF10 PLEKHG3 0 0 0 297 1 1
    TNFSF10 MYO1B 0 0 113 209 1 1
    TNFSF10 CTLA4 0 0 451 469 1 1
    TNFSF10 RNASEL 0 0 262 290 1 1
    TNFSF10 DDIT4 0 0 171 185 1 1
    TNFSF10 CCDC174 0 0 0 347 1 1
    TNFSF10 IFI44 0 0 372 516 1 1
    TNFSF10 CD38 0 0 252 276 1 1
    TNFSF10 BCL2 0 0 181 181 1 2
    TNFSF10 MDK 0 0 95 254 1 1
    TNFSF10 ANXA7 0 0 108 169 1 2
    TNFSF10 BAK1 0 0 370 370 1 2
    TNFSF10 TXN 0 0 173 173 1 1
    TNFSF10 BMPR2 0 0 57 151 1 1
    TNFSF10 CCNE1 0 0 135 189 1 1
    TNFSF10 HRK 0 0 359 359 1 1
    TNFSF10 SFTPD 0 0 81 177 1 1
    TNFSF10 HGF 0 0 322 321 1 1
    TNFSF10 PECAM1 0 0 212 262 1 1
    TNFSF10 CAT 0 0 260 274 1 1
    TNFSF10 CCL1 0 0 156 155 1 1
    TNFSF10 HELZ2 0 0 113 285 1 1
    TNFSF10 KIR3DL1 0 0 266 266 1 1
    TNFSF10 CACYBP 0 0 0 330 1 1
    TNFSF10 FCGR1A 0 0 251 279 1 1
    TNFSF10 REM1 0 0 0 155 1 1
    TNFSF10 RPS6KB1 0 0 170 298 1 2
    TNFSF10 TNFAIP8 0 0 112 191 1 1
    TNFSF10 BAD 0 0 261 261 1 1
    TNFSF10 AHR 0 0 150 171 1 1
    TNFSF10 SERPINE1 0 0 204 204 1 1
    TNFSF10 PPP2CA 270 0 75 295 1 1
    TNFSF10 CDK1 0 0 209 209 1 1
    TNFSF10 EIF4E 0 0 136 155 1 1
    TNFSF10 MUC1 0 0 203 203 1 1
    TNFSF10 PGR 0 0 188 188 1 1
    TNFSF10 IFT43 0 0 159 158 1 1
    TNFSF10 KLRG1 0 0 218 218 1 1
    TNFSF10 NTRK1 0 0 194 194 1 1
    TNFSF10 GNLY 0 0 285 327 1 1
    TNFSF10 DDX60 0 0 81 335 1 1
    TNFSF10 VNN2 0 0 0 183 1 1
    TNFSF10 IRAK2 0 0 170 177 1 1
    TNFSF10 ANXA2 0 0 134 216 1 1
    TNFSF10 SERPINE2 0 0 112 203 1 1
    TNFSF10 FIBCD1 0 0 59 471 1 1
    TNFSF10 FAM3B 0 0 60 168 1 1
    TNFSF10 ZNF22 0 0 155 160 1 1
    TNFSF10 IFIT2 0 0 343 499 1 1
    TNFSF10 CD19 0 0 358 363 1 1
    TNFSF10 ICAM2 0 0 96 272 1 1
    TNFSF10 BCL2L2 0 0 405 405 1 1
    TNFSF10 CCND1 0 0 362 362 1 1
    TNFSF10 TNFRSF10D 732 900 769 996 1 1
    TNFSF10 CD274 0 0 403 439 1 1
    TNFSF10 CSF2RB 0 0 82 196 1 1
    TNFSF10 MTF2 0 0 0 248 1 1
    TNFSF10 AIMP1 0 0 124 184 1 1
    TNFSF10 PRKAA1 0 0 103 160 1 2
    TNFSF10 PLEKHG2 0 0 0 185 1 1
    TNFSF10 SEMA3A 0 0 53 150 1 1
    TNFSF10 AHNAK 0 0 0 179 1 1
    TNFSF10 FLT3LG 0 0 138 170 1 1
    TNFSF10 NOS3 0 0 161 161 1 1
    TNFSF10 HLA-E 0 0 293 357 1 1
    TNFSF10 IFNAR1 0 0 324 325 1 1
    TNFSF10 CCND2 0 0 143 172 1 1
    TNFSF10 TNFAIP6 0 0 240 307 1 1
    TNFSF10 TFRC 0 0 170 169 1 1
    TNFSF10 ENSG00000272980 0 0 193 210 1 1
    TNFSF10 IL1R2 0 0 207 252 1 1
    TNFSF10 MAP3K14 0 0 115 152 1 1
    TNFSF10 CD70 0 0 382 406 1 1
    TNFSF10 RPS6KA2 0 0 102 197 1 1
    TNFSF10 CD63 0 0 202 202 1 1
    TNFSF10 VWF 0 0 124 184 1 1
    TNFSF10 IL5 0 0 341 341 1 1
    TNFSF10 TNFAIP3 270 0 321 502 1 1
    TNFSF10 EMP3 0 0 73 176 1 1
    TNFSF10 GCG 0 0 66 160 1 1
    TNFSF10 NFKB2 0 0 284 284 1 1
    TNFSF10 S100A9 0 0 62 185 1 1
    TNFSF10 RELB 0 0 289 305 1 2
    TNFSF10 DRAM1 0 0 161 195 1 2
    TNFSF10 TIGIT 0 0 145 181 1 1
    TNFSF10 BCAP31 0 0 150 164 1 1
    TNFSF10 CXCL3 0 0 213 213 1 1
    TNFSF10 FGF2 0 0 298 298 1 1
    TNFSF10 CD9 0 0 167 167 1 1
    TNFSF10 TNFSF14 0 0 392 192 1 1
    TNFSF10 BMF 0 0 322 321 1 1
    TNFSF10 TYMP 0 0 107 196 1 1
    TNFSF10 TXNIP 0 0 109 189 1 1
    TNFSF10 IFNL2 0 0 167 167 1 1
    TNFSF10 IFI16 0 0 246 303 1 1
    TNFSF10 BCL2A1 0 0 394 443 1 1
    TNFSF10 IFI35 0 0 229 381 1 1
    TNFSF10 IFNL1 0 0 186 186 1 1
    TNFSF10 GADD45A 0 0 307 335 1 1
    TNFSF10 FAM216B 0 0 100 156 1 1
    TNFSF10 ATF3 0 0 213 213 1 1
    TNFSF10 GBP5 0 0 123 410 1 1
    TNFSF10 DDX53 0 0 195 195 1 1
    TNFSF10 UVRAG 0 0 108 152 1 2
    TNFSF10 CSF1R 0 0 229 316 1 1
    TNFSF10 APOL1 0 0 124 227 1 2
    TNFSF10 APOB 0 0 81 175 1 1
    TNFSF10 IGF1 0 0 321 321 1 1
    TNFSF10 ITIH4 0 0 259 258 1 1
    TNFSF10 MAPK1 0 900 240 920 1 2
    TNFSF10 IRF7 0 0 392 454 1 1
    TNFSF10 BTK 0 0 438 459 1 1
    TNFSF10 THBS2 0 0 120 167 1 1
    TNFSF10 SOCS1 0 0 262 262 1 1
    TNFSF10 PLOD2 0 0 108 230 1 1
    TNFSF10 ULBP2 0 0 233 232 1 1
    TNFSF10 NCR3LG1 0 0 122 210 1 1
    TNFSF10 IFITM1 0 0 256 304 1 1
    TNFSF10 TANK 0 0 180 179 1 1
    TNFSF10 PSD2 0 0 46 196 1 1
    TNFSF10 TNF 0 0 862 870 1 1
    TNFSF10 C22orf29 0 0 402 402 1 1
    TNFSF10 HLA-DMA 0 0 122 174 1 1
    TNFSF10 ITGA9 0 0 96 269 1 1
    TNFSF10 CD44 0 0 320 334 1 1
    TNFSF10 NT5E 0 0 202 202 1 1
    TNFSF10 IL7 0 0 371 386 1 1
    TNFSF10 MMP3 0 0 202 251 1 1
    TNFSF10 IL1RN 0 0 320 385 1 1
    TNFSF10 IP6K1 0 0 397 396 1 1
    TNFSF10 CASP2 0 0 391 390 1 1
    TNFSF10 NR4A2 0 0 122 157 1 1
    TNFSF10 TP53TG5 0 0 155 174 1 1
    TNFSF10 BAG4 0 0 229 312 1 1
    TNFSF10 NAIP 0 0 284 284 1 1
    TNFSF10 MMP7 0 0 190 252 1 1
    TNFSF10 IFI27 0 0 324 364 1 1
    TNFSF10 IFI30 0 0 108 164 1 1
    TNFSF10 MS4A6A 0 0 0 163 1 1
    TNFSF10 CD209 0 0 165 185 1 1
    TNFSF10 HERC6 0 0 203 301 1 1
    TNFSF10 BAHD1 0 0 0 557 1 1
    TNFSF10 ZNF207 0 0 95 157 1 1
    TNFSF10 IL23R 0 0 124 199 1 1
    TNFSF10 PIBF1 0 0 46 296 1 1
    TNFSF10 PDGFC 0 0 75 158 1 1
    TNFSF10 BFAR 0 0 181 196 1 1
    TNFSF10 TRMT12 0 0 113 162 1 1
    TNFSF10 ETS1 0 0 125 150 1 1
    TNFSF10 PCSK1 0 0 240 239 1 1
    TNFSF10 OLFM4 0 0 0 153 1 1
    TNFSF10 IL17A 0 0 394 394 1 1
    TNFSF10 TNRC18 0 0 0 254 1 1
    TNFSF10 IGFBP1 0 0 144 156 1 1
    TNFSF10 PLAU 0 0 205 205 1 1
    TNFSF10 MS4A7 0 0 0 163 1 1
    TNFSF10 EGF 0 0 344 343 1 1
    TNFSF10 CD59 0 0 184 183 1 1
    TNFSF10 BMP2 0 0 145 160 1 1
    TNFSF10 CHEK2 0 0 180 179 1 1
    TNFSF10 GADD45B 0 0 163 163 1 1
    TNFSF10 RPS6KA3 0 0 122 352 1 1
    TNFSF10 CYCS 0 0 654 654 1 1
    TNFSF10 NRP1 0 0 156 155 1 1
    TNFSF10 CXCL11 0 0 395 462 1 1
    TNFSF10 MAPK9 0 0 171 171 1 2
    TNFSF10 THSD1 0 0 67 167 1 1
    TNFSF10 TLR7 0 0 401 422 1 1
    TNFSF10 IL18BP 0 0 134 201 1 1
    TNFSF10 CASP9 0 0 653 653 1 1
    TNFSF10 ANXA13 0 0 96 187 1 1
    TNFSF10 ITGA8 0 0 51 230 1 1
    TNFSF10 TRAF6 0 0 302 302 1 2
    TNFSF10 PPARA 0 0 153 152 1 1
    TNFSF10 TRIB1 0 0 295 295 1 1
    TNFSF10 IER3 192 0 120 258 1 1
    TNFSF10 CXCL9 0 0 422 503 1 1
    TNFSF10 TEK 0 0 156 155 1 1
    TNFSF10 TATDN2 0 0 0 258 1 1
    TNFSF10 HSP90B1 0 0 154 153 1 1
    TNFSF10 ITGA1 0 0 284 284 1 1
    TNFSF10 NUCB2 0 0 60 406 1 1
    TNFSF10 HSPB3 0 0 193 193 1 1
    TNFSF10 CCR2 0 0 297 347 1 2
    TNFSF10 ANKRD66 0 0 113 168 1 1
    TNFSF10 ISG20 0 0 255 424 1 1
    TNFSF10 NXPH2 0 0 73 236 1 1
    TNFSF10 PIK3R1 0 900 135 909 1 1
    TNFSF10 CX3CR1 0 0 210 233 1 1
    TNFSF10 TRIM5 0 0 139 201 1 2
    TNFSF10 ENSG00000266953 0 0 0 371 1 1
    TNFSF10 HSPA4 0 0 270 270 1 1
    TNFSF10 IRF2 0 0 212 257 1 1
    TNFSF10 PMEL 0 0 160 159 1 1
    TNFSF10 LIF 0 0 204 204 1 1
    TNFSF10 PTGER4 0 0 134 175 1 1
    TNFSF10 CD244 0 0 235 280 1 1
    TNFSF10 CISH 0 0 212 235 1 1
    TNFSF10 PRF1 0 0 607 637 1 1
    TNFSF10 IL2RG 0 0 193 302 1 1
    TNFSF10 MX2 0 0 306 389 1 1
    TNFSF10 KLRF1 0 0 184 216 1 1
    TNFSF10 CCR1 0 0 261 314 1 1
    TNFSF10 SNX29 0 0 48 183 1 1
    TNFSF10 CTGF 0 0 183 183 1 1
    TNFSF10 RCSD1 0 0 0 244 1 1
    TNFSF10 IFIH1 0 0 315 500 1 1
    TNFSF10 HIST2H3PS2 0 0 171 171 1 1
    TNFSF10 DIABLO 0 0 837 837 1 1
    TNFSF10 FAM136A 0 0 62 268 1 1
    TNFSF10 TNS1 0 0 170 240 1 1
    TNFSF10 API5 0 0 103 186 1 1
    TNFSF10 LILRB2 0 0 54 174 1 1
    TNFSF10 TBX3 0 0 52 373 1 1
    TNFSF10 MAP2K4 0 0 154 153 1 1
    TNFSF10 PLD1 0 0 0 420 1 1
    TNFSF10 TNS4 0 0 48 435 1 1
    TNFSF10 HLA-DQA1 0 0 137 181 1 1
    TNFSF10 SERPING1 0 0 116 217 1 1
    TNFSF10 MAPK8 0 0 325 329 1 2
    TNFSF10 ARG1 0 0 218 218 1 1
    TNFSF10 PRND 0 0 407 407 1 1
    TNFSF10 CAMTA1 0 0 0 330 1 1
    TNFSF10 FRZB 0 0 108 156 1 1
    TNFSF10 ADIPOQ 0 0 161 161 1 1
    TNFSF10 KLRD1 0 0 391 390 1 1
    TNFSF10 CD33 0 0 170 190 1 1
    TNFSF10 BCL2L10 0 0 296 296 1 1
    TNFSF10 CDH1 0 0 282 282 1 1
    TNFSF10 CSRNP2 0 0 0 188 1 1
    TNFSF10 TRIM21 0 0 91 167 1 1
    TNFSF10 PLG 0 0 205 205 1 1
    TNFSF10 MMD 0 0 0 190 1 1
    TNFSF10 USP32 0 0 87 161 1 1
    TNFSF10 KMT2B 0 0 82 291 1 1
    TNFSF10 CDK6 0 0 218 218 1 1
    TNFSF10 TTLL1 0 0 89 151 1 1
    TNFSF10 AIM2 0 0 209 242 1 1
    TNFSF10 DDX58 0 0 369 494 1 1
    TNFSF10 AGER 0 0 163 163 1 1
    TNFSF10 PIK3AP1 0 0 0 151 1 1
    TNFSF10 TRADD 0 900 606 960 1 1
    TNFSF10 ALK 0 0 138 156 1 1
    TNFSF10 CRYGC 0 0 216 216 1 1
    TNFSF10 KLHL6 0 0 93 216 1 1
    TNFSF10 MAVS 0 0 231 230 1 1
    TNFSF10 FNDC1 0 0 113 208 1 1
    TNFSF10 H2AFX 0 0 155 154 1 1
    TNFSF10 IL1A 0 0 413 412 1 1
    TNFSF10 CEACAM1 0 0 134 191 1 1
    TNFSF10 RHOB 0 0 150 176 1 1
    TNFSF10 CCL4 0 0 407 466 1 1
    TNFSF10 GBP1 0 0 295 512 1 1
    TNFSF10 NFIL3 0 0 243 280 1 1
    TNFSF10 ATG16L2 0 0 113 191 1 2
    TNFSF10 DRD2 0 0 66 209 1 1
    TNFSF10 NODAL 0 0 59 154 1 1
    TNFSF10 TYROBP 0 0 181 290 1 1
    TNFSF10 PHF11 0 0 109 248 1 1
    TNFSF10 CASP7 0 0 519 525 1 1
    TNFSF10 PGK1 0 0 91 154 1 2
    TNFSF10 TNFAIP8L2 0 0 73 179 1 1
    TNFSF10 ANXA3 0 0 134 219 1 1
    TNFSF10 FNDC3A 0 0 0 292 1 1
    TNFSF10 ITGB1 0 0 134 227 1 1
    TNFSF10 CD68 0 0 193 232 1 1
    TNFSF10 CASP8 899 900 870 998 1 2
    TNFSF10 ALB 0 0 409 409 1 1
    TNFSF10 CCL2 0 0 467 481 1 2
    TNFSF10 CD276 0 0 300 300 1 1
    TNFSF10 IFNE 0 0 70 164 1 1
    TNFSF10 IL16 0 0 297 318 1 1
    TNFSF10 IFI6 0 0 432 464 1 1
    TNFSF10 IDO1 0 0 244 286 1 1
    TNFSF10 IFI44L 0 0 244 439 1 1
    TNFSF10 TNFRSF10A 974 900 989 999 1 1
    TNFSF10 MADD 0 0 131 152 1 1
    TNFSF10 CNTF 0 0 52 155 1 1
    TNFSF10 ANXA8 0 0 310 309 1 1
    TNFSF10 BIRC3 0 0 519 574 1 1
    TNFSF10 IL17F 0 0 150 197 1 1
    TNFSF10 SMAD3 0 0 156 155 1 1
    TNFSF10 IL9 0 0 281 294 1 1
    TNFSF10 DHRS12 0 0 155 154 1 1
    TNFSF10 IL4 0 0 418 418 1 1
    TNFSF10 RIBC2 0 0 412 412 1 1
    TNFSF10 EP300 0 0 156 155 1 1
    TNFSF10 PDGFRB 0 0 188 206 1 1
    TNFSF10 PROM1 0 0 211 211 1 1
    TNFSF10 ANGPT1 0 0 155 166 1 1
    TNFSF10 THY1 0 0 161 161 1 1
    TNFSF10 MAPK3 0 900 321 929 1 2
    TNFSF10 B2M 0 0 261 337 1 1
    TNFSF10 PSD4 0 0 0 160 1 1
    TNFSF10 MMP9 0 0 363 379 1 1
    TNFSF10 HSPE1 0 0 89 229 1 1
    TNFSF10 FCGR2B 0 0 214 273 1 1
    TNFSF10 MICB 0 0 284 284 1 1
    TNFSF10 SQSTM1 0 0 202 202 1 2
    TNFSF10 BNIP3 0 0 284 284 1 2
    TNFSF10 PDGFD 0 0 128 219 1 1
    TNFSF10 ANXA4 0 0 74 201 1 1
    TNFSF10 KIR3DL3 0 0 170 169 1 1
    TNFSF10 GIMAP4 0 0 48 326 1 1
    TNFSF10 ACTB 0 0 459 468 1 1
    TNFSF10 AK2 0 0 537 537 1 1
    TNFSF10 SELP 0 0 161 222 1 1
    TNFSF10 INS 0 0 322 321 1 1
    TNFSF10 CCL15 0 0 145 164 1 1
    TNFSF10 DNMT1 0 0 203 203 1 1
    TNFSF10 RPS6KA6 0 0 0 177 1 1
    TNFSF10 CD40 0 0 470 489 1 1
    TNFSF10 ITGB7 0 0 90 175 1 1
    TNFSF10 SELL 0 0 293 343 1 1
    TNFSF10 HTRA2 0 0 364 364 1 1
    TNFSF10 IFIT5 0 0 127 244 1 1
    TNFSF10 CEBPA 0 0 140 157 1 1
    TNFSF10 DMRTA1 0 0 43 208 1 1
    TNFSF10 SP100 0 0 140 248 1 1
    TNFSF10 SOX2 0 0 157 174 1 1
    TNFSF10 CRP 0 0 261 261 1 1
    TNFSF10 TP73 0 0 232 313 1 2
    TNFSF10 SLAMF6 0 0 134 183 1 1
    TNFSF10 PTGDR 0 0 142 163 1 1
    TNFSF10 HSP90AA1 0 0 321 321 1 2
    TNFSF10 BCL3 0 0 83 179 1 1
    TNFSF10 IL3 0 0 321 321 1 1
    TNFSF10 LTB 0 0 242 309 1 1
    TNFSF10 MBOAT1 0 0 0 363 1 1
    TNFSF10 MLNR 0 0 0 537 1 1
    TNFSF10 HPGDS 0 0 194 215 1 1
    TNFSF10 LRRC3 0 0 0 254 1 1
    TNFSF10 CTAG1B 0 0 161 161 1 1
    TNFSF10 ZEB1 0 0 181 181 1 1
    TNFSF10 CD24 0 0 158 157 1 1
    TNFSF10 GALNT3 0 0 90 153 1 1
    TNFSF10 IL22 0 0 150 165 1 1
    TNFSF10 ICAM1 0 0 391 413 1 1
    TNFSF10 RHBDF2 0 0 0 208 1 1
    TNFSF10 MLKL 0 0 459 487 1 1
    TNFSF10 BCL10 0 0 217 217 1 1
    TNFSF10 SMDT1 0 0 170 169 1 1
    TNFSF10 ITGAV 0 0 167 198 1 1
    TNFSF10 CXCR1 0 0 180 209 1 1
    TNFSF10 FYB 0 0 0 156 1 1
    TNFSF10 EHHADH 0 0 62 156 1 1
    TNFSF10 NPSR1 0 0 0 206 1 1
    TNFSF10 CD160 0 0 153 152 1 1
    TNFSF10 PTPRC 0 0 325 393 1 1
    TNFSF10 CD3D 0 0 100 156 1 1
    TNFSF10 KLRK1 0 0 518 545 1 1
    TNFSF10 TLR5 0 0 260 305 1 1
    TNFSF10 CCL18 0 0 141 181 1 1
    TNFSF10 CXCL12 0 0 377 377 1 1
    TNFSF10 TIMP1 0 0 284 284 1 1
    TNFSF10 HLA-DOA 0 0 73 209 1 1
    TNFSF10 BAX 0 0 403 403 1 2
    TNFSF10 GPR29 0 0 193 193 1 1
    TNFSF10 TNFRSF14 0 0 290 352 1 1
    TNFSF10 BCLAF1 0 0 113 238 1 1
    TNFSF10 SPP1 0 0 233 232 1 1
    TNFSF10 CDKN1A 0 0 334 334 1 2
    TNFSF10 CSF2RA 0 0 90 203 1 1
    TNFSF10 AR 0 0 246 245 1 1
    TNFSF10 RHOA 0 0 157 156 1 1
    TNFSF10 PARP1 0 0 283 284 1 2
    TNFSF10 EPCAM 0 0 184 183 1 1
    TNFSF10 IFNAR2 0 0 202 231 1 1
    TNFSF10 GDF10 0 0 81 177 1 1
    TNFSF10 FGL2 0 0 150 365 1 1
    TNFSF10 CD1C 0 0 216 254 1 1
    TNFSF10 BID 0 900 507 948 1 1
    TNFSF10 HSPA8 0 0 181 192 1 2
    TNFSF10 GSR 0 0 123 154 1 1
    TNFSF10 MMP2 0 0 347 362 1 1
    TNFSF10 SLAMF1 0 0 134 199 1 1
    TNFSF10 TNFRSF13C 0 0 181 189 1 1
    TNFSF10 NEDD9 0 0 73 211 1 1
    TNFSF10 ANGPT2 0 0 124 178 1 1
    TNFSF10 TNFRSF8 0 0 299 299 1 1
    TNFSF10 TNFSF4 0 0 380 380 1 1
    TNFSF10 COL3A1 0 0 93 157 1 1
    TNFSF10 COIL 0 0 51 307 1 1
    TNFSF10 PDXDC1 0 0 0 250 1 1
    TNFSF10 RIPK2 0 0 260 288 1 1
    TNFSF10 CD8A 0 0 561 573 1 1
    TNFSF10 BIK 0 0 324 323 1 1
    TNFSF10 CALR 0 0 230 229 1 1
    TNFSF10 IGFBP3 0 0 204 204 1 1
    TNFSF10 PSMB8 0 0 181 262 1 1
    TNFSF10 RAB27A 0 0 82 183 1 1
    TNFSF10 HAVCR2 0 0 235 262 1 1
    TNFSF10 EIF2AK2 0 0 296 345 1 2
    TNFSF10 COMP 0 0 330 344 1 1
    TNFSF10 ALX1 0 0 0 190 1 1
    TNFSF10 CCR5 0 0 336 408 1 1
    TNFSF10 IL7R 0 0 286 335 1 1
    TNFSF10 RTP4 0 0 151 432 1 1
    TNFSF10 CDC25C 0 0 163 163 1 1
    TNFSF10 LTA 0 0 391 407 1 1
    TNFSF10 GTPBP4 0 0 448 448 1 1
    TNFSF10 APOL6 0 0 105 226 1 1
    TNFSF10 CD69 0 0 370 398 1 1
    TNFSF10 PARP14 0 0 166 332 1 1
    TNFSF10 IFNK 0 0 142 220 1 1
    TNFSF10 LCK 0 0 174 173 1 1
    TNFSF10 JAG1 0 0 134 153 1 1
    TNFSF10 IL17RA 0 0 107 172 1 1
    TNFSF10 CCRL2 0 0 195 284 1 1
    TNFSF10 TICAM1 0 0 181 198 1 1
    TNFSF10 NFKBIE 0 0 157 156 1 1
    TNFSF10 PVRL2 0 0 205 205 1 1
    TNFSF10 FDPS 0 0 108 199 1 1
    TNFSF10 GRB2 0 0 134 150 1 1
    TNFSF10 FYN 0 0 144 334 1 1
    TNFSF10 GRIN2A 0 0 0 208 1 1
    TNFSF10 MSLN 0 0 158 157 1 1
    TNFSF10 TYK2 0 0 152 171 1 1
    TNFSF10 DAPK1 0 0 252 252 1 2
    TNFSF10 JUN 0 0 468 468 1 1
    TNFSF10 NRG3 0 0 0 175 1 1
    TNFSF10 MMD2 0 0 74 420 1 1
    TNFSF10 SIGLEC1 0 0 108 170 1 1
    TNFSF10 CCL24 0 0 170 208 1 1
    TNFSF10 ENSG00000173366 0 0 401 400 1 1
    TNFSF10 SERPINA1 0 0 94 161 1 2
    TNFSF10 MAPK12 0 0 123 320 1 1
    TNFSF10 ITGAL 0 0 236 281 1 1
    TNFSF10 FSCN1 0 0 162 229 1 1
    TNFSF10 BCL2L11 0 0 556 556 1 1
    TNFSF10 IL10RA 0 0 193 286 1 1
    TNFSF10 GZMA 0 0 324 403 1 1
    TNFSF10 BOK 0 0 151 150 1 2
    TNFSF10 SH2D3C 0 0 0 488 1 1
    TNFSF10 PIK3CG 0 0 124 183 1 1
    TNFSF10 JAK3 0 0 122 154 1 1
    TNFSF10 ZBTB16 0 0 134 176 1 1
    TNFSF10 CAV1 0 0 155 154 1 1
    TNFSF10 GBP4 0 0 210 322 1 1
    TNFSF10 HLA-DRB1 0 0 112 164 1 1
    TNFSF10 COL18A1 0 0 210 210 1 1
    TNFSF10 HSPA1A 0 0 203 232 1 1
    TNFSF10 MPZL1 0 0 46 193 1 1
    TNFSF10 CCR3 0 0 152 151 1 1
    TNFSF10 CASP1 0 0 459 612 1 2
    TNFSF10 PVR 0 0 249 248 1 1
    TNFSF10 CCNA2 0 0 217 249 1 1
    TNFSF10 DNTT 0 0 325 325 1 1
    TNFSF10 CHEK1 0 0 202 202 1 1
    TNFSF10 CD27 0 0 390 407 1 1
    TNFSF10 CD74 0 0 208 288 1 1
    TNFSF10 CXCL6 0 0 181 191 1 1
    TNFSF10 PI4K2B 0 0 46 220 1 1
    TNFSF10 PLAT 0 0 124 164 1 1
    TNFSF10 AOC3 0 0 142 162 1 1
    TNFSF10 CCL4L1 0 0 294 295 1 1
    TNFSF10 RORA 0 0 103 194 1 1
    TNFSF10 BCL2L1 0 0 651 651 1 2
    TNFSF10 RELA 0 0 339 339 1 1
    TNFSF10 ENSG00000026036 0 0 541 541 1 1
    TNFSF10 KCNK1 0 0 0 206 1 1
    TNFSF10 MBOAT2 0 0 0 248 1 1
    TNFSF10 NFKB1 0 0 322 341 1 1
    TNFSF10 LGALS3BP 0 0 163 215 1 1
    TNFSF10 CD7 0 0 134 159 1 1
    TNFSF10 C1R 0 0 96 155 1 1
    TNFSF10 STAT4 0 0 161 205 1 1
    TNFSF10 CASP6 0 0 415 414 1 1
    TNFSF10 ITGA4 0 0 141 194 1 1
    TNFSF10 ZAP70 0 0 160 178 1 1
    TNFSF10 CLEC7A 0 0 145 186 1 1
    TNFSF10 TLR10 0 0 175 175 1 1
    TNFSF10 TRIM25 0 0 108 151 1 1
    TNFSF10 PIK3R4 0 0 95 151 1 2
    TNFSF10 HS3ST1 0 0 0 248 1 1
    TNFSF10 KITLG 0 0 261 261 1 1
    TNFSF10 DPP3 0 0 66 258 1 1
    TNFSF10 SNRPD3 0 0 0 207 1 1
    TNFSF10 MAP2K7 0 0 358 358 1 1
    TNFSF10 PLEKHG1 0 0 46 435 1 1
    TNFSF10 CX3CL1 0 0 265 270 1 1
    TNFSF10 NOS2 0 0 173 173 1 1
    TNFSF10 ABL1 0 0 181 181 1 1
    TNFSF10 TNFSF15 0 0 689 295 1 1
    TNFSF10 NMI 0 0 0 158 1 1
    TNFSF10 OAS2 0 0 324 477 1 1
    TNFSF10 CD14 0 0 54 171 1 1
    TNFSF10 CD83 0 0 284 284 1 1
    TNFSF10 GAPDH 0 0 417 416 1 2
    TNFSF10 ZMAT4 0 0 92 218 1 1
    TNFSF10 LRRC3C 0 0 90 256 1 1
    TNFSF10 TNFRSF25 0 0 563 601 1 1
    TNFSF10 LARS2 0 0 54 303 1 1
    TNFSF10 TLR4 0 0 504 527 1 1
    TNFSF10 HCST 0 0 139 193 1 1
    TNFSF10 CREB1 0 0 233 232 1 1
    TNFSF10 GSDMD 0 0 150 181 1 1
    TNFSF10 TGFB3 0 0 188 277 1 1
    TNFSF10 CADM3 0 0 47 212 1 1
    TNFSF10 CCL5 0 0 469 525 1 1
    TNFSF10 USP9X 0 0 291 290 1 1
    TNFSF10 PLCG2 0 0 107 178 1 1
    TNFSF10 ZNFX1 0 0 60 207 1 1
    TNFSF10 IL2RB 0 0 290 327 1 1
    TNFSF10 IFNG 0 0 409 517 1 2
    TNFSF10 BIRC2 0 0 561 561 1 1
    TNFSF10 CREBBP 0 0 124 158 1 1
    TNFSF10 MBOAT4 0 0 0 187 1 1
    TNFSF10 SLC5A5 0 0 142 164 1 1
    TNFSF10 UBE2D3 0 0 46 189 1 1
    TNFSF10 CCL13 0 0 155 182 1 1
    TNFSF10 ARHGAP30 0 0 0 154 1 1
    TNFSF10 EPO 0 0 183 183 1 1
    TNFSF10 TNFSF9 0 0 350 349 1 1
    TNFSF10 C5AR1 0 0 66 288 1 1
    TNFSF10 AGAP2 0 0 0 256 1 1
    TNFSF10 CXCL13 0 0 250 277 1 1
    TNFSF10 PLK1 0 0 162 161 1 1
    TNFSF10 TNFSF18 0 0 358 358 1 1
    TNFSF10 SLC4A7 0 0 0 248 1 1
    TNFSF10 IL4R 0 0 122 172 1 1
    TNFSF10 SIRT2 0 0 166 165 1 2
    TNFSF10 NCS1 0 0 0 222 1 1
    TNFSF10 PERP 0 0 157 175 1 1
    TNFSF10 FOXM1 0 0 135 153 1 1
    TNFSF10 LGALS9 0 0 388 538 1 1
    TNFSF10 TNFSF13 0 0 293 402 1 1
    TNFSF10 CCNB1 0 0 240 239 1 1
    TNFSF10 CNTN1 0 0 0 208 1 1
    TNFSF10 ZDHHC17 192 0 0 192 1 1
    TNFSF10 ANXA5 0 0 557 557 1 1
    TNFSF10 ADAR 0 0 155 177 1 1
    TNFSF10 CD163 0 0 181 275 1 1
    TNFSF10 GIMAP8 0 0 95 299 1 1
    TNFSF10 ANXA11 0 0 96 186 1 1
    TNFSF10 POTEF 0 0 181 195 1 1
    TNFSF10 GIMAP6 0 0 60 239 1 1
    TNFSF10 BCAR3 0 0 0 272 1 1
    TNFSF10 PDCD5 0 0 88 197 1 1
    TNFSF10 FAM43A 0 0 165 183 1 1
    TNFSF10 MTOR 0 0 334 334 1 2
    TNFSF10 CD40LG 0 0 469 488 1 1
    TNFSF10 VNN1 0 0 91 236 1 1
    TNFSF10 ENTPD1 0 0 129 187 1 1
    TNFSF10 NOTCH1 0 0 253 252 1 1
    TNFSF10 PTPN13 0 0 181 243 1 1
    TNFSF10 MMP1 0 0 241 324 1 1
    TNFSF10 CXCR4 0 0 391 390 1 2
    TNFSF10 CYR61 0 0 161 161 1 1
    TNFSF10 FGF13 0 0 150 173 1 1
    TNFSF10 HLA-G 0 0 163 163 1 1
    TNFSF10 CTAG1A 0 0 161 161 1 1
    TNFSF10 PIDD1 0 0 236 236 1 1
    TNFSF10 TRAF4 0 0 230 247 1 1
    TNFSF10 PLEK 0 0 74 186 1 1
    TNFSF10 TBX2 0 0 47 201 1 1
    TNFSF10 IL17D 0 0 81 178 1 1
    TNFSF10 TNFRSF1A 0 0 784 788 1 1
    TNFSF10 GZMB 0 0 505 555 1 1
    TNFSF10 BATF2 0 0 122 178 1 1
    TNFSF10 BCL2L2-PABPN1 0 0 391 390 1 1
    TNFSF10 STAT1 0 0 460 566 1 1
    TNFSF10 ENDOG 0 0 370 370 1 1
    TNFSF10 DCXR 0 0 391 390 1 1
    TNFSF10 TNFRSF19 0 0 226 226 1 1
    TNFSF10 IL6 0 0 556 556 1 1
    TNFSF10 CXCL14 0 0 162 224 1 1
    TNFSF10 PIK3C3 0 0 164 178 1 2
    TNFSF10 IL3RA 0 0 260 284 1 1
    TNFSF10 MPO 0 0 166 165 1 1
    TNFSF10 BTLA 0 0 157 182 1 1
    TNFSF10 IL6R 0 0 205 234 1 1
    TNFSF10 NCR1 0 0 464 467 1 1
    TNFSF10 KLK3 0 0 229 228 1 1
    TNFSF10 NCR3 0 0 401 419 1 1
    TNFSF10 CXCL8 0 0 517 531 1 1
    TNFSF10 MAPK13 0 0 68 295 1 1
    TNFSF10 NDRG1 0 0 134 188 1 1
    TNFSF10 ID1 0 0 77 214 1 1
    TNFSF10 IL1B 0 0 529 552 1 1
    TNFSF10 SP1 0 0 161 161 1 1
    TNFSF10 TRAF5 0 0 323 323 1 1
    TNFSF10 OAS1 0 0 372 510 1 1
    TNFSF10 EDN1 0 0 181 181 1 1
    TNFSF10 HIF1A 0 0 321 321 1 2
    TNFSF10 BAG3 0 0 210 227 1 2
    TNFSF10 ACSL5 0 0 66 192 1 1
    TNFSF10 HERC5 0 0 170 266 1 1
    TNFSF10 IKBKE 0 0 123 463 1 1
    TNFSF10 ERAP1 0 0 96 215 1 1
    TNFSF10 LIAS 0 0 107 162 1 1
    TNFSF10 PRKAR2B 0 0 90 185 1 1
    TNFSF10 TNFRSF1B 0 0 454 486 1 1
    TNFSF10 C3AR1 0 0 123 258 1 1
    TNFSF10 CXCR2 0 0 247 264 1 1
    TNFSF10 EGR1 0 0 259 258 1 1
    TNFSF10 GIMAP5 0 0 0 190 1 1
    TNFSF10 CDK2 0 0 271 271 1 1
    TNFSF10 FCGR3A 0 0 392 452 1 1
    TNFSF10 HRAS 0 0 325 338 1 1
    TNFSF10 CDH20 0 0 55 258 1 1
    TNFSF10 CTNNB1 0 0 335 335 1 1
    TNFSF10 NR4A1 0 0 144 162 1 1
    TNFSF10 CCL26 0 0 108 248 1 1
    TNFSF10 SEMA3D 0 0 0 206 1 1
    TNFSF10 FCER2 0 0 57 182 1 1
    TNFSF10 APAF1 0 0 601 601 1 1
    TNFSF10 MTA3 0 0 0 192 1 1
    TNFSF10 HDAC6 0 0 179 179 1 2
    TNFSF10 PAK1 270 0 0 270 1 1
    TNFSF10 NLRC5 0 0 94 161 1 1
    TNFSF10 JAK2 0 0 270 296 1 1
    TNFSF10 HBEGF 0 0 402 402 1 1
    TNFSF10 ITGB8 0 0 61 161 1 1
    TNFSF10 IFNA2 0 0 285 284 1 1
    TNFSF10 EZH2 0 0 172 171 1 1
    TNFSF10 STAT3 0 0 451 463 1 2
    TNFSF10 CSRNP3 0 0 125 582 1 1
    TNFSF10 TGFA 0 0 202 202 1 1
    TNFSF10 GATA3 0 0 204 204 1 1
    TNFSF10 BRF1 0 0 82 485 1 1
    TNFSF10 SIVA1 0 0 150 313 1 1
    TNFSF10 ERN1 0 0 217 217 1 2
    TNFSF10 MICA 0 0 321 321 1 1
    TNFSF10 TNFRSF4 0 0 340 364 1 1
    TNFSF10 MYD88 0 0 386 418 1 1
    TNFSF10 FES 0 0 47 163 1 1
    TNFSF10 MAP3K13 0 0 155 154 1 1
    TNFSF10 CDK4 0 0 275 275 1 1
    TNFSF10 CFLAR 871 600 782 989 1 1
    TNFSF10 EGFR 0 0 418 423 1 1
    TNFSF10 FBXO6 0 0 104 194 1 1
    TNFSF10 LAMP1 0 0 284 284 1 2
    TNFSF10 FADD 897 900 879 998 1 2
    TNFSF10 PEBP4 0 0 516 516 1 1
    TNFSF10 ULBP3 0 0 156 155 1 1
    TNFSF10 ATP6V0C 0 0 0 210 1 2
    TNFSF10 CKS1B 0 0 49 308 1 1
    TNFSF10 IRF9 0 0 255 349 1 1
    TNFSF10 TGM2 0 0 108 152 1 1
    TNFSF10 KLRC1 0 0 392 405 1 1
    TNFSF10 TP53 0 0 672 672 1 2
    TNFSF10 LCN2 0 0 143 175 1 1
    TNFSF10 TTLL9 0 0 60 208 1 1
    TNFSF10 MDM2 0 0 323 323 1 1
    TNFSF10 CRADD 0 0 217 217 1 1
    TNFSF10 TNFRSF11B 213 0 742 820 1 1
    TNFSF10 NFKBIZ 0 0 134 166 1 1
    TNFSF10 LAMA4 0 0 73 169 1 1
    TNFSF10 PRR15 0 0 69 167 1 1
    TNFSF10 ZBP1 0 0 163 221 1 1
    TNFSF10 LCP2 0 0 107 232 1 1
    TNFSF10 KIR3DL2 0 0 193 209 1 1
    TNFSF10 DDIT3 0 0 321 321 1 2
    TNFSF10 SELPLG 0 0 123 172 1 1
    TNFSF10 MAP3K7 0 0 213 213 1 1
    TNFSF10 TRAF1 0 0 341 365 1 1
    TNFSF10 PGBD4 0 0 0 179 1 1
    TNFSF10 GZMH 0 0 123 194 1 1
    TNFSF10 RAF1 0 0 160 159 1 2
    TNFSF10 LMNA 0 0 171 171 1 1
    TNFSF10 PDCD2 0 0 47 194 1 1
    TNFSF10 CSF3 0 0 345 345 1 1
    TNFSF10 LGALS2 0 0 89 152 1 1
    TNFSF10 IRAK1 0 0 203 203 1 1
    TNFSF10 CYB561A3 0 0 70 166 1 1
    TNFSF10 ACSL1 0 0 63 188 1 1
    TNFSF10 LAG3 0 0 225 224 1 1
    TNFSF10 UBD 0 0 82 156 1 1
    TNFSF10 LY75 0 0 101 166 1 1
    TNFSF10 NELFCD 0 0 160 159 1 1
    TNFSF10 MOAP1 0 0 210 210 1 1
    TNFSF10 TNFRSF13B 0 0 181 189 1 1
    TNFSF10 CASP10 486 900 566 982 1 1
    TNFSF10 CIDEB 0 0 95 154 1 1
    TNFSF10 INHBA 0 0 128 217 1 1
    TNFSF10 CTSE 0 0 155 154 1 1
    TNFSF10 CLEC4A 0 0 107 161 1 1
    TNFSF10 NOL3 0 0 240 319 1 1
    TNFSF10 SMAD4 0 0 155 154 1 1
    TNFSF10 OAS3 0 0 261 342 1 1
    TNFSF10 MYCN 0 0 181 181 1 1
    TNFSF10 TNFRSF12A 0 0 335 335 1 1
    TNFSF10 MAP3K8 0 0 107 229 1 1
    TNFSF10 PPIF 0 0 170 169 1 1
    TNFSF10 MAP2K1 0 0 296 296 1 1
    TNFSF10 C5 0 0 81 181 1 1
    TNFSF10 OSM 0 0 138 170 1 1
    TNFSF10 DHX58 0 0 248 322 1 1
    TNFSF10 BRI3BP 0 0 81 189 1 1
    TNFSF10 AREG 0 0 181 181 1 1
    TNFSF10 RBCK1 0 0 155 154 1 1
    TNFSF10 OASL 0 0 323 407 1 1
    TNFSF10 CD80 0 0 394 428 1 1
    TNFSF10 STK11 0 0 153 152 1 2
    TNFSF10 BRCA1 0 0 235 235 1 1
    TNFSF10 CCL21 0 0 181 300 1 1
    TNFSF10 PDGFB 0 0 210 210 1 1
    TNFSF10 CIDEA 0 0 107 162 1 1
    TNFSF10 LILRB1 0 0 140 181 1 1
    TNFSF10 PGAM5 0 0 165 165 1 1
    TNFSF10 TLR1 0 0 325 403 1 1
    TNFSF10 NFE2L2 0 0 155 154 1 1
    TNFSF10 PI3 0 0 177 207 1 1
    TNFSF10 TNFRSF6B 0 0 393 392 1 1
    TNFSF10 PCK1 0 0 66 161 1 1
    TNFSF10 TREM1 0 0 141 201 1 1
    TNFSF10 SLAMF7 0 0 118 192 1 1
    TNFSF10 IGF1R 0 0 286 286 1 1
    TNFSF10 CKS2 0 0 81 239 1 1
    TNFSF10 TAB2 0 0 155 154 1 1
    TNFSF10 IL18 0 0 469 482 1 1
    TNFSF10 IFNA1 0 0 557 557 1 1
    TNFSF10 PARP12 0 0 152 259 1 1
    TNFSF10 TMEFF2 0 0 0 189 1 1
    TNFSF10 ITGAE 0 0 235 235 1 1
    TNFSF10 MYC 0 0 407 407 1 2
    TNFSF10 IRGM 0 0 166 185 1 2
    TNFSF10 IL15 0 0 505 516 1 1
    TNFSF10 IFITM3 0 0 156 197 1 1
    TNFSF10 RARRES3 0 0 170 317 1 1
    TNFSF10 IL1R1 0 0 268 290 1 1
    TNFSF10 ACP5 74 0 150 219 1 1
    TNFSF10 IL2RA 0 0 266 301 1 1
    TNFSF10 PIK3CA 0 900 170 913 1 2
    TNFSF10 TOP1 0 0 212 212 1 1
    TNFSF10 CLEC11A 0 0 294 294 1 1
    TNFSF10 CEACAM5 0 0 203 203 1 1
    TNFSF10 MX1 0 0 414 513 1 1
    TNFSF10 TAB1 0 0 180 179 1 1
    TNFSF10 TRAF2 270 900 392 951 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0045569 Molecular Function TRAIL binding enables IEA
    GO:0005125 Molecular Function cytokine activity enables IBA
    GO:0005125 Molecular Function cytokine activity enables IDA
    GO:0042802 Molecular Function identical protein binding enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0005102 Molecular Function signaling receptor binding enables TAS
    GO:0005164 Molecular Function tumor necrosis factor receptor binding enables IEA
    GO:0008270 Molecular Function zinc ion binding enables IDA
    GO:0036462 Biological Process TRAIL-activated apoptotic signaling pathway involved_in IDA
    GO:0006915 Biological Process apoptotic process involved_in TAS
    GO:0007166 Biological Process cell surface receptor signaling pathway involved_in IBA
    GO:0007267 Biological Process cell-cell signaling involved_in TAS
    GO:0006955 Biological Process immune response involved_in IEA
    GO:0008584 Biological Process male gonad development involved_in IEA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
    GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IBA
    GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IEP
    GO:2001238 Biological Process positive regulation of extrinsic apoptotic signaling pathway involved_in IBA
    GO:2001238 Biological Process positive regulation of extrinsic apoptotic signaling pathway involved_in IDA
    GO:0090200 Biological Process positive regulation of release of cytochrome c from mitochondria involved_in IDA
    GO:0032868 Biological Process response to insulin involved_in IEA
    GO:0007165 Biological Process signal transduction involved_in TAS
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005576 Cellular Component extracellular region located_in TAS
    GO:0005615 Cellular Component extracellular space is_active_in IBA
    GO:0005615 Cellular Component extracellular space is_active_in IDA
    GO:0005886 Cellular Component plasma membrane located_in IEA
    Pathways
    Name DB ID
    Apoptosis Reactome R-HSA-109581
    Caspase activation via Death Receptors in the presence of ligand Reactome R-HSA-140534
    Signal Transduction Reactome R-HSA-162582
    Regulation by c-FLIP Reactome R-HSA-3371378
    RIPK1-mediated regulated necrosis Reactome R-HSA-5213460
    Regulated Necrosis Reactome R-HSA-5218859
    CASP8 activity is inhibited Reactome R-HSA-5218900
    Caspase activation via extrinsic apoptotic signalling pathway Reactome R-HSA-5357769
    Programmed Cell Death Reactome R-HSA-5357801
    Regulation of necroptotic cell death Reactome R-HSA-5675482
    Dimerization of procaspase-8 Reactome R-HSA-69416
    Death Receptor Signaling Reactome R-HSA-73887
    TRAIL signaling Reactome R-HSA-75158
    Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
    TP53 network (WP1742) WikiPathways WP1742_r116592
    Apoptosis (WP254) WikiPathways WP254_r118382
    Photodynamic therapy-induced AP-1 survival signaling (WP3611) WikiPathways WP3611_r120501
    Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_033994 2 miscRNA transcript variant 4 NC_000003 Reference
    NM_001190942 2 mRNA transcript variant 2 NC_000003 Reference
    NM_003810 4 mRNA transcript variant 1 NC_000003 Reference
    NM_001190943 2 mRNA transcript variant 3 NC_000003 Reference