ATG10

autophagy related 10
General Information
Name autophagy related 10
Alias
  • ubiquitin-like-conjugating enzyme ATG10
  • APG10 autophagy 10-like
  • ATG10 autophagy related 10 homolog
  • autophagy-related protein 10
Synonyms DKFZP586I0418 FLJ13954 APG10 APG10L pp12616
Gene_family Autophagy related
organism Homo sapiens
entrez_id 83734
location 5q14.1-q14.2
transcript_count 14
exon_count 15
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
      Stringdb Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis; Belongs to the ATG10 family
      nextProt E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ATG10 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
    ATG10 BioGRID SCN2B GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID ATG7 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID ATG12 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID USP11 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID POLR1B GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPF2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID KAT8 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID UTP15 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID VMP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID WDR82 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID NOL10 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ATG9A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NOC4L GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID DDX54 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID TUT1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID VPS16 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NOM1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID TRAPPC11 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATG101 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID LSM2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID DHX37 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID VPS18 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MCOLN1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID UTP3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ATXN7L3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID XAB2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID UTP6 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID WDR12 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID IARS2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID KANSL3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RFK GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID BRF2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID IMP3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID VPS13D GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID HEATR1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PAK1IP1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID BANP GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID WDR74 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID NLE1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID KCTD5 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID LSM8 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID LSM7 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NOP58 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID NOP16 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ATP6V1D GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID DDX47 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RSL24D1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PIK3R4 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NRBF2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MYLIP GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TBK1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MED4 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID UTP20 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID VPS4A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID VPS41 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID AATF GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID GNL3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID LYSET GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID WIPI2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID DCAF13 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID LSM5 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID GTPBP4 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PES1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PPWD1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RRP12 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID WDR43 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ATG2A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID SNRNP200 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT5 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATG14 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID LSM6 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID WDR45 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID POLR3A GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPP14 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID DDX52 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CLP1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID WDR3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CCT8 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID PRPF8 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT4 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT7 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RPP30 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID NOP56 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CAP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MCRS1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID EMG1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RACK1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID SAP18 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RCL1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID MED6 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID MED12 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID WDR1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RB1CC1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATG13 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID AQR GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RBM39 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATP6V1G1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MED7 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID EFTUD2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MED14 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PRPF4 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID UBA3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TAX1BP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID LDB1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID BECN1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CUL3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID BAP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CHAF1B GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID YEATS4 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RAB7A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID XPO1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID UROS GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID UROD GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID U2AF1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TTC1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TOP2A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TCP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TAF7 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID TAF6 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID STAT5B GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID SRSF2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID SFPQ GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID RPS28 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS24 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS23 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS21 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS19 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS18 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS16 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS15A GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS14 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS13 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS11 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS10 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS9 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS7 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS4X GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPS2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPL34 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPL7A GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RPL4 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID RAB1A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID QARS1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PWP2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PTPN1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID PPAT GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID POLR2L GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PIK3C3 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID PFAS GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PDPK1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PCYT1A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID OGDH GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NPC1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NEDD8 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NCBP1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID MTHFD1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID MAT2A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID NBR1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID EIF6 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID IARS1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID HNRNPK GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID BRF1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID GTF2B GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID GRB2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID GDI2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID GART GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID FECH GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID FAU GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID FBL GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID EIF1AX GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID DLST GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID DHFR GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID DDX10 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CSTF3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CSE1L GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CFL1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCT6A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID CCNH GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID CAPZB GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID BCR GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ATP6V1C1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATP6V1B2 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ATP6V1A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ALDOA GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID ACTL6A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ACTB GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID ACP1 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID TMEM41B GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MED11 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID DHX36 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID TRAPPC5 GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID FTSJ3 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID BUD23 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID IMP4 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID TSR2 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID LTV1 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID PHF5A GeneID BioGRID Phenotypic Enhancement
    ATG10 BioGRID MAK16 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID MED10 GeneID BioGRID Phenotypic Suppression
    ATG10 BioGRID IRGM GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATG10 BioGRID IFNL2 GeneID BioGRID Affinity Capture-Western
    ATG10 BioGRID ATG5 GeneID BioGRID Two-hybrid
    ATG10 BioGRID ATG3 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID ATG4B GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID HAT1 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID USP7 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID RBBP7 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID MAP1B GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID KRT85 GeneID BioGRID Affinity Capture-MS
    ATG10 BioGRID ADSS2 GeneID BioGRID Affinity Capture-MS
    ATG10 Protein ATG5 GeneID HPRD None
    ATG10 Protein ATG7 GeneID HPRD None
    ATG10 Protein ATG12 GeneID HPRD None
    StringDB
    A B experiments database textmining combined score hadb nhadb
    ATG10 SMURF1 0 0 162 161 1 1
    ATG10 CASP3 0 0 268 268 1 2
    ATG10 ZNF404 0 0 167 167 1 1
    ATG10 PSEN1 0 0 134 166 1 2
    ATG10 ATG101 0 0 735 895 1 2
    ATG10 HSPB8 0 0 174 173 1 2
    ATG10 PLEKHM1 0 0 270 270 1 2
    ATG10 HSP90AA1 0 0 170 180 1 2
    ATG10 TFEB 0 0 392 392 1 2
    ATG10 CTSZ 0 0 49 154 1 1
    ATG10 ATG4D 0 0 562 718 1 2
    ATG10 NDUFAF5 0 0 0 223 1 1
    ATG10 DIRAS3 0 0 154 153 1 2
    ATG10 PLEKHD1 0 0 180 179 1 1
    ATG10 ULK4 0 0 134 208 1 1
    ATG10 KEAP1 0 0 235 235 1 2
    ATG10 BNIP3 0 0 467 523 1 2
    ATG10 SQSTM1 0 0 651 711 1 2
    ATG10 RNF5 0 0 118 180 1 1
    ATG10 ATP6AP1L 0 0 372 372 1 1
    ATG10 ATG12 675 800 989 999 1 2
    ATG10 ACTB 0 0 184 183 1 1
    ATG10 PRMT2 0 0 0 169 1 1
    ATG10 ATG13 0 0 808 921 1 2
    ATG10 INS 0 0 180 179 1 1
    ATG10 USP11 272 0 0 272 1 1
    ATG10 CTSS 0 0 134 254 1 1
    ATG10 UBA2 0 0 91 303 1 1
    ATG10 CUL3 0 0 156 155 1 1
    ATG10 WDR41 0 0 150 226 1 2
    ATG10 HAT1 275 0 0 275 1 1
    ATG10 ATG9A 0 0 504 810 1 2
    ATG10 RAB24 0 0 233 399 1 2
    ATG10 HSPA8 0 0 370 373 1 2
    ATG10 RIPK1 0 0 167 167 1 1
    ATG10 GABARAPL1 59 650 805 946 1 2
    ATG10 VPS16 0 0 268 275 1 1
    ATG10 RALB 0 0 193 193 1 1
    ATG10 ATG16L1 0 650 940 988 1 2
    ATG10 C6orf106 0 0 0 372 1 1
    ATG10 RAB1A 0 0 125 217 1 2
    ATG10 RAB11FIP1 0 0 52 154 1 1
    ATG10 ZC3H6 0 0 156 155 1 1
    ATG10 NOD2 0 0 202 202 1 1
    ATG10 PRDX1 0 0 60 201 1 1
    ATG10 DEPTOR 0 0 253 252 1 1
    ATG10 MNT 0 0 52 154 1 1
    ATG10 MIB2 0 0 45 211 1 1
    ATG10 VCP 0 0 107 158 1 2
    ATG10 LAMP2 59 0 469 531 1 2
    ATG10 EI24 0 0 240 239 1 2
    ATG10 FOXO1 0 0 181 181 1 2
    ATG10 MLST8 0 0 255 254 1 2
    ATG10 SAE1 0 0 0 265 1 1
    ATG10 TBC1D25 0 0 138 161 1 1
    ATG10 FUNDC1 0 0 325 340 1 2
    ATG10 HSPA5 0 0 181 243 1 2
    ATG10 MFN1 0 0 183 183 1 1
    ATG10 EIF2AK2 0 0 107 160 1 2
    ATG10 ULK2 0 0 632 714 1 2
    ATG10 PIK3CG 0 0 143 336 1 1
    ATG10 TOLLIP 0 0 167 168 1 1
    ATG10 ATXN3 0 0 138 177 1 1
    ATG10 LRRK2 0 0 180 181 1 2
    ATG10 PIK3CB 0 0 67 162 1 1
    ATG10 PMAIP1 0 0 162 161 1 1
    ATG10 SNX4 0 0 73 163 1 1
    ATG10 AKT1S1 0 0 181 181 1 1
    ATG10 SCAMP5 0 0 82 179 1 1
    ATG10 CASP1 0 0 167 167 1 2
    ATG10 SNAP29 0 0 340 344 1 2
    ATG10 MOCS3 0 0 181 372 1 1
    ATG10 SNCA 94 0 260 300 1 2
    ATG10 BECN1 0 0 758 906 1 2
    ATG10 DAPK1 0 0 293 298 1 2
    ATG10 C14orf166 0 0 160 159 1 1
    ATG10 ITPR3 0 0 162 161 1 1
    ATG10 JUN 0 0 170 169 1 1
    ATG10 SEC62 0 0 143 236 1 1
    ATG10 UBA6 0 0 71 288 1 1
    ATG10 BCL2L11 0 0 162 161 1 1
    ATG10 TSC1 0 0 125 189 1 2
    ATG10 LONP2 0 0 0 315 1 1
    ATG10 WDR18 0 0 123 219 1 1
    ATG10 SVIP 0 0 170 169 1 1
    ATG10 LRRC57 0 0 134 227 1 1
    ATG10 ATG5 423 600 988 998 1 2
    ATG10 CALCOCO2 0 0 508 514 1 2
    ATG10 PSMD4 0 0 150 169 1 1
    ATG10 RPTOR 0 0 332 357 1 2
    ATG10 UFM1 0 0 202 290 1 1
    ATG10 MIB1 0 0 0 208 1 1
    ATG10 HSPA4 0 0 150 190 1 1
    ATG10 XBP1 0 0 218 239 1 2
    ATG10 ENSG00000100926 0 0 161 195 1 1
    ATG10 SIRT1 0 0 262 262 1 2
    ATG10 MCL1 0 0 216 216 1 2
    ATG10 SMCR8 0 0 138 191 1 2
    ATG10 RAB8B 0 0 75 217 1 2
    ATG10 CTSB 0 0 218 253 1 2
    ATG10 TMEM59 0 0 142 159 1 1
    ATG10 COQ2 0 0 0 207 1 1
    ATG10 SH3GLB1 0 0 556 575 1 2
    ATG10 PDIK1L 0 0 0 256 1 1
    ATG10 GADD45B 0 0 0 258 1 1
    ATG10 CYCS 0 0 266 266 1 1
    ATG10 HMGB1 0 0 220 220 1 2
    ATG10 TLR7 0 0 160 159 1 1
    ATG10 UBQLN2 0 0 134 160 1 2
    ATG10 ATG4A 0 0 608 748 1 2
    ATG10 OPTN 0 0 455 455 1 2
    ATG10 TRAF6 0 0 182 181 1 2
    ATG10 ULK1 0 0 739 797 1 2
    ATG10 VPS33A 0 0 194 212 1 1
    ATG10 TBC1D14 0 0 112 167 1 2
    ATG10 MED31 0 0 67 170 1 1
    ATG10 MAPK8 0 0 293 293 1 2
    ATG10 PEX5 0 0 155 177 1 1
    ATG10 UFC1 0 0 113 174 1 1
    ATG10 IPO4 0 0 60 163 1 1
    ATG10 VAMP3 0 0 107 196 1 1
    ATG10 USP30 0 0 139 162 1 1
    ATG10 SESN2 0 0 215 216 1 2
    ATG10 EIF5AL1 0 0 170 190 1 1
    ATG10 VPS18 0 0 197 202 1 1
    ATG10 WDFY4 0 0 0 347 1 1
    ATG10 MAP1LC3B 118 650 601 913 1 2
    ATG10 MAP1LC3C 130 650 566 890 1 2
    ATG10 MAP1B 129 0 140 238 1 1
    ATG10 ATG7 674 600 989 999 1 2
    ATG10 ATG16L2 0 0 505 751 1 2
    ATG10 FMN1 0 0 0 269 1 1
    ATG10 TBC1D2 0 0 154 155 1 1
    ATG10 UBE2S 0 0 231 230 1 1
    ATG10 ATM 0 0 151 166 1 1
    ATG10 VTI1B 0 0 261 303 1 2
    ATG10 BCL2L13 0 0 206 219 1 1
    ATG10 CTSD 0 0 278 304 1 2
    ATG10 DDX58 0 0 167 167 1 1
    ATG10 RAB9B 0 0 0 209 1 1
    ATG10 FBXL20 0 0 60 162 1 1
    ATG10 C12orf5 0 0 152 187 1 1
    ATG10 DRAM2 0 0 204 235 1 2
    ATG10 PEX12 0 0 87 290 1 1
    ATG10 AMBRA1 0 0 681 702 1 2
    ATG10 PRMT3 0 0 0 169 1 1
    ATG10 FAM134B 0 0 261 265 1 1
    ATG10 GOPC 0 0 190 235 1 2
    ATG10 LGALS8 0 0 193 193 1 1
    ATG10 STK35 0 0 0 256 1 1
    ATG10 PRMT6 0 0 0 169 1 1
    ATG10 PTEN 0 0 236 240 1 2
    ATG10 GABARAP 59 650 689 915 1 2
    ATG10 CASP8 0 0 260 260 1 2
    ATG10 KIAA0226 0 0 468 482 1 1
    ATG10 SEC22A 0 0 92 210 1 1
    ATG10 WIPI1 0 0 710 830 1 2
    ATG10 RNF14 0 0 61 182 1 1
    ATG10 CD300C 0 0 504 504 1 1
    ATG10 CANX 0 0 120 155 1 2
    ATG10 ATG2A 0 0 518 755 1 2
    ATG10 RAB9A 0 0 0 209 1 2
    ATG10 EIF2AK4 0 0 218 246 1 1
    ATG10 RAB8A 0 0 91 164 1 2
    ATG10 MCOLN1 0 0 157 156 1 1
    ATG10 CAT 0 0 181 210 1 1
    ATG10 ERN1 0 0 234 234 1 2
    ATG10 MYCBP2 0 0 49 153 1 1
    ATG10 TECPR1 0 0 422 481 1 2
    ATG10 HGS 0 0 107 162 1 2
    ATG10 CISD2 0 0 212 219 1 2
    ATG10 CD46 0 0 141 157 1 1
    ATG10 HDAC6 0 0 281 282 1 2
    ATG10 APAF1 0 0 167 167 1 1
    ATG10 RHEB 0 0 326 332 1 2
    ATG10 VAMP8 0 0 342 357 1 2
    ATG10 BCAS3 0 0 71 372 1 2
    ATG10 VPS4B 0 0 136 168 1 1
    ATG10 MAP1A 0 0 370 413 1 1
    ATG10 EPG5 0 0 294 402 1 2
    ATG10 CTSA 0 0 90 184 1 1
    ATG10 DDIT3 0 0 211 211 1 2
    ATG10 PRKAA1 0 0 127 182 1 2
    ATG10 ULK3 0 0 209 387 1 2
    ATG10 URM1 0 0 194 194 1 1
    ATG10 HTT 0 0 307 343 1 1
    ATG10 TP53INP2 0 0 166 165 1 2
    ATG10 RPS6KB1 0 0 252 252 1 2
    ATG10 RFWD2 0 0 81 176 1 1
    ATG10 EGFR 0 0 143 161 1 1
    ATG10 CFLAR 0 0 152 151 1 1
    ATG10 LAMP1 0 0 391 413 1 2
    ATG10 FADD 0 0 193 198 1 2
    ATG10 STBD1 0 0 155 154 1 2
    ATG10 MED16 0 0 66 169 1 1
    ATG10 KPNA4 0 0 0 165 1 1
    ATG10 SESN1 0 0 136 173 1 2
    ATG10 TGM2 0 0 118 212 1 1
    ATG10 PRMT8 0 0 0 169 1 1
    ATG10 TP53 0 0 292 292 1 2
    ATG10 FBXW2 0 0 57 160 1 1
    ATG10 PSMA6 0 0 0 258 1 1
    ATG10 STK11 0 0 256 256 1 2
    ATG10 BRCA1 0 0 166 165 1 1
    ATG10 UVRAG 0 0 683 766 1 2
    ATG10 UBE2K 0 0 203 248 1 1
    ATG10 WDFY3 0 0 391 585 1 2
    ATG10 IGF1 0 0 143 229 1 1
    ATG10 RB1CC1 0 0 796 893 1 2
    ATG10 WDR45 0 0 349 493 1 2
    ATG10 RAB23 0 0 66 228 1 2
    ATG10 NFE2L2 0 0 163 163 1 1
    ATG10 PEX10 0 0 83 287 1 1
    ATG10 ACTA1 0 0 136 192 1 1
    ATG10 VPS39 0 0 160 159 1 1
    ATG10 PRDX2 0 0 0 185 1 1
    ATG10 TAX1BP1 0 0 184 183 1 2
    ATG10 ATG4B 314 0 681 853 1 2
    ATG10 UBA1 0 0 94 305 1 1
    ATG10 DRAM1 0 0 467 482 1 2
    ATG10 RAB7A 0 0 518 602 1 2
    ATG10 PRDX4 0 0 0 185 1 1
    ATG10 IFNL2 270 0 140 345 1 1
    ATG10 FNBP1L 0 0 95 195 1 1
    ATG10 UBL3 0 0 0 380 1 1
    ATG10 ATP13A2 0 0 99 187 1 2
    ATG10 FIS1 0 0 163 180 1 2
    ATG10 WIPI2 0 0 609 771 1 2
    ATG10 WDR45B 0 0 370 509 1 1
    ATG10 MED17 0 0 55 159 1 1
    ATG10 GLIPR2 0 0 123 219 1 2
    ATG10 ENSG00000261832 0 0 206 224 1 1
    ATG10 PPP1R15A 0 0 137 157 1 2
    ATG10 RICTOR 0 0 150 169 1 2
    ATG10 PI3 0 0 211 211 1 1
    ATG10 NBR1 0 0 603 819 1 2
    ATG10 TECPR2 0 0 144 177 1 2
    ATG10 TNF 0 0 165 165 1 1
    ATG10 GPSM3 0 0 137 156 1 1
    ATG10 C22orf29 0 0 234 234 1 1
    ATG10 VPS11 0 0 160 172 1 2
    ATG10 PARK2 45 0 341 373 1 1
    ATG10 RNF185 0 0 113 175 1 1
    ATG10 MYC 0 0 141 158 1 2
    ATG10 IRGM 270 0 561 671 1 2
    ATG10 TM9SF1 0 0 160 194 1 2
    ATG10 FBXO18 0 0 57 160 1 1
    ATG10 AEN 0 0 113 168 1 1
    ATG10 GABARAPL2 59 650 805 946 1 2
    ATG10 ATF6 0 0 281 286 1 2
    ATG10 GAPDH 0 0 170 169 1 2
    ATG10 ATG14 0 0 760 856 1 2
    ATG10 SSBP4 0 0 162 161 1 1
    ATG10 RNF6 0 0 62 164 1 1
    ATG10 VMP1 0 0 470 589 1 2
    ATG10 TMEM74 0 0 265 339 1 2
    ATG10 PARL 0 0 212 212 1 1
    ATG10 CARM1 0 0 66 156 1 1
    ATG10 FYCO1 0 0 234 235 1 2
    ATG10 BCL2L1 0 0 370 370 1 2
    ATG10 AKT1 0 0 340 364 1 2
    ATG10 RAB33B 0 0 218 245 1 2
    ATG10 MTMR14 0 0 127 150 1 1
    ATG10 UBA5 0 0 171 364 1 1
    ATG10 CEP85 0 0 122 276 1 1
    ATG10 PIK3R4 0 0 734 898 1 2
    ATG10 MXD1 0 0 47 151 1 1
    ATG10 ATF4 0 0 181 181 1 2
    ATG10 GBAS 0 0 148 171 1 1
    ATG10 UBE2B 0 0 52 155 1 1
    ATG10 ZKSCAN3 0 0 171 195 1 2
    ATG10 PRDX3 0 0 0 185 1 1
    ATG10 UBA7 0 0 88 301 1 1
    ATG10 HMGXB4 0 0 101 157 1 1
    ATG10 MAP1LC3B2 332 0 254 663 1 2
    ATG10 FBXL17 0 0 67 169 1 1
    ATG10 UBQLN1 0 0 150 175 1 2
    ATG10 PINK1 0 0 414 545 1 2
    ATG10 PEX6 0 0 62 207 1 1
    ATG10 LONP1 0 0 43 317 1 1
    ATG10 ATG3 279 0 913 974 1 2
    ATG10 VPS4A 0 0 146 161 1 1
    ATG10 BNIP1 0 0 159 158 1 2
    ATG10 SYNPO2L 0 0 76 151 1 1
    ATG10 PIRT 0 0 194 194 1 1
    ATG10 EIF2AK3 0 0 234 248 1 2
    ATG10 PIK3C3 0 0 756 906 1 2
    ATG10 CHMP2B 0 0 158 187 1 2
    ATG10 EEA1 0 0 144 229 1 1
    ATG10 KRT85 301 0 0 301 1 1
    ATG10 EVA1A 0 0 244 253 1 2
    ATG10 FOXO3 0 0 261 307 1 2
    ATG10 ENSG00000250232 0 0 141 331 1 1
    ATG10 MTOR 0 0 557 590 1 2
    ATG10 PRMT1 0 0 0 169 1 1
    ATG10 ATG4C 0 0 608 748 1 2
    ATG10 PEX2 0 0 122 317 1 1
    ATG10 VAMP7 0 0 184 240 1 1
    ATG10 BNIP3L 0 0 466 497 1 2
    ATG10 SNX18 0 0 160 161 1 2
    ATG10 VDAC1 0 0 150 163 1 2
    ATG10 GOLT1B 0 0 84 203 1 1
    ATG10 TSC2 0 0 391 418 1 2
    ATG10 RAB7B 0 0 519 603 1 1
    ATG10 ZFYVE1 0 0 560 560 1 2
    ATG10 RIPK3 0 0 133 172 1 1
    ATG10 EXOC8 0 0 95 230 1 1
    ATG10 MFN2 0 0 213 213 1 2
    ATG10 APP 0 0 150 169 1 1
    ATG10 USP7 204 0 0 204 1 1
    ATG10 MAP1LC3A 0 650 646 901 1 2
    ATG10 NRBF2 0 0 260 260 1 2
    ATG10 CTSL 0 0 151 204 1 1
    ATG10 CLN3 0 0 202 220 1 2
    ATG10 PIR 0 0 57 487 1 1
    ATG10 ATG2B 0 0 562 777 1 2
    ATG10 TBK1 0 0 213 213 1 2
    ATG10 SEC13 0 0 66 159 1 1
    ATG10 IL1B 0 0 180 179 1 1
    ATG10 STX17 0 0 519 536 1 2
    ATG10 UBA3 0 0 141 347 1 1
    ATG10 RCCD1 0 0 210 210 1 1
    ATG10 RAB11A 0 0 218 218 1 1
    ATG10 RAB5A 0 0 288 303 1 2
    ATG10 NAE1 0 0 95 306 1 1
    ATG10 ZNF414 0 0 145 276 1 1
    ATG10 HIF1A 0 0 181 181 1 2
    ATG10 BAG3 0 0 209 209 1 2
    ATG10 EIF2S1 0 0 206 220 1 2
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0061651 Molecular Function Atg12 conjugating enzyme activity enables IBA
    GO:0061651 Molecular Function Atg12 conjugating enzyme activity enables IDA
    GO:0019777 Molecular Function Atg12 transferase activity enables ISS
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0006983 Biological Process ER overload response involved_in IMP
    GO:0000045 Biological Process autophagosome assembly involved_in IBA
    GO:0000045 Biological Process autophagosome assembly involved_in IDA
    GO:0006914 Biological Process autophagy involved_in IMP
    GO:0000423 Biological Process mitophagy involved_in IBA
    GO:0031401 Biological Process positive regulation of protein modification process involved_in ISS
    GO:0006497 Biological Process protein lipidation involved_in ISS
    GO:0032446 Biological Process protein modification by small protein conjugation involved_in IBA
    GO:0032446 Biological Process protein modification by small protein conjugation involved_in IDA
    GO:0015031 Biological Process protein transport involved_in IEA
    GO:0005829 Cellular Component cytosol located_in TAS
    Pathways
    Name DB ID
    Macroautophagy Reactome R-HSA-1632852
    Autophagy Reactome R-HSA-9612973
    Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
    Host-pathogen interaction of human coronaviruses - autophagy (WP4863) WikiPathways WP4863_r124639
    Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway (WP4577) WikiPathways WP4577_r123500
    Nanoparticle triggered autophagic cell death (WP2509) WikiPathways WP2509_r101755
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_047417800 1 mRNA transcript variant X5 NC_000005 Reference
    XM_047417803 1 mRNA transcript variant X10 NC_000005 Reference
    NM_001131028 2 mRNA transcript variant 3 NC_000005 Reference
    XM_017009944 2 mRNA transcript variant X7 NC_000005 Reference
    NM_031482 5 mRNA transcript variant 2 NC_000005 Reference
    XM_005248612 4 mRNA transcript variant X6 NC_000005 Reference
    XM_047417798 1 mRNA transcript variant X1 NC_000005 Reference
    XM_047417802 1 mRNA transcript variant X9 NC_000005 Reference
    XM_005248611 6 mRNA transcript variant X3 NC_000005 Reference
    XM_047417799 1 mRNA transcript variant X4 NC_000005 Reference
    XM_005248610 6 mRNA transcript variant X2 NC_000005 Reference
    XM_047417801 1 mRNA transcript variant X8 NC_000005 Reference
    XM_011543660 3 mRNA transcript variant X11 NC_000005 Reference
    XM_011543661 3 mRNA transcript variant X12 NC_000005 Reference