CAPNS1

calpain small subunit 1
General Information
Name calpain small subunit 1
Alias
  • calpain small subunit 1
  • CANP small subunit
  • calcium-activated neutral proteinase small subunit
  • calcium-dependent protease small subunit 1
  • calcium-dependent protease, small subunit
  • calpain 4, small subunit (30K)
  • calpain regulatory subunit
  • calpain, small polypeptide
  • epididymis secretory sperm binding protein
Synonyms CANP CANPS 30K CDPS CALPAIN4 CAPN4 CSS1
Gene_family EF-hand domain containing
organism Homo sapiens
entrez_id 826
location 19q13.12
transcript_count 7
exon_count 11
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
      Stringdb Calpain small subunit 1; Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; EF-hand domain containing
      nextProt Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    CAPNS1 BioGRID CAPN1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Cross-Linking-MS (XL-MS)
    CAPNS1 BioGRID ATG5 GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID C9orf72 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID SERBP1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID KCTD7 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
    CAPNS1 BioGRID CUL3 GeneID BioGRID Affinity Capture-Western
    CAPNS1 BioGRID DNAH17 GeneID BioGRID Cross-Linking-MS (XL-MS)
    CAPNS1 BioGRID CFTR GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID UBE2H GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID ANLN GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID RPA2 GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID RPA1 GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID SPOP GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CLEC16A GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TENT5C GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID RAF1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CDK7 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CCNF GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    CAPNS1 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID PRKN GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID KIF1B GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID CDC42BPB GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID H1-4 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID CAPN2 GeneID BioGRID Affinity Capture-MS; Co-crystal Structure; Co-fractionation
    CAPNS1 BioGRID WWP1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID VCP GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID RAB7A GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID MAP4 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TNF GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID ESR1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID SPANXN4 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CAPNS2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID ADSS2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID SMYD1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID SARNP GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CDC42 GeneID BioGRID Reconstituted Complex
    CAPNS1 BioGRID F2RL1 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID EMC1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID SHC1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID GRB2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID E7 GeneID BioGRID PCA
    CAPNS1 BioGRID MAGEA3 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID WWP2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA; Co-fractionation
    CAPNS1 BioGRID YWHAE GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID UBA1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID SSBP1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID SPARC GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID FH GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ECH1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID C1QBP GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ATIC GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ALDH1B1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ALDH2 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID DIABLO GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID IARS2 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID AGR2 GeneID BioGRID Proximity Label-MS
    CAPNS1 BioGRID PIH1D1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID AAR2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID EFTUD2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CFAP418 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID DUSP19 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID KNG1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID FNTB GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID USP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    CAPNS1 BioGRID AGTRAP GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID HUWE1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID NEDD1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TUBGCP2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TUBGCP3 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CDC20 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID OGFOD1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID STK26 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ISOC1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID DCPS GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID MAT2B GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PLPBP GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID FERMT2 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID YWHAQ GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PDIA4 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID YWHAZ GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID YWHAH GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID YWHAG GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PTMA GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PPP1CA GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PAK2 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID PAFAH1B1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID MYO1E GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID MAT2A GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID GNAI3 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID GAPDH GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID EIF5 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID TBCB GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ALDH7A1 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ASNS GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID ADRB2 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID PPARGC1A GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID VCAM1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID TRAF5 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID STAT3 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID ITGA4 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID FN1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID CSPG4 GeneID BioGRID Co-fractionation
    CAPNS1 BioGRID POU5F1 GeneID BioGRID Affinity Capture-RNA
    CAPNS1 BioGRID MEPCE GeneID BioGRID Affinity Capture-MS
    CAPNS1 BioGRID RUVBL1 GeneID BioGRID Affinity Capture-MS
    CAPNS1 Protein GNB2 GeneID HPRD None
    CAPNS1 Protein LRRCC1 GeneID HPRD None
    CAPNS1 Protein TERF1 GeneID HPRD None
    CAPNS1 Protein IL2RG GeneID HPRD None
    CAPNS1 Protein ARR3 GeneID HPRD None
    CAPNS1 Protein ARHGEF6 GeneID HPRD None
    CAPNS1 Protein RAB1A GeneID HPRD None
    CAPNS1 Protein CDK4 GeneID HPRD None
    CAPNS1 Protein CAPN2 GeneID HPRD None
    CAPNS1 Protein CAPN1 GeneID HPRD None
    CAPNS1 Protein CAST GeneID HPRD None
    CAPNS1 Protein ATP5MF GeneID HPRD None
    CAPNS1 Protein DRG1 GeneID HPRD None
    CAPNS1 Protein GET4 GeneID HPRD None
    CAPNS1 BioGRID IL2RG GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID GET4 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID ATP5MF GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID TERF1 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID RAB1A GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID DRG1 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID GNB2 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID CDK4 GeneID BioGRID Two-hybrid
    CAPNS1 BioGRID ARR3 GeneID BioGRID Two-hybrid
    CAPNS1 Protein CAPN1 GeneID BIND CAPN1 interacts with CAPNS1.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    CAPNS1 SHMT2 0 0 48 214 1 1
    CAPNS1 APP 0 650 95 702 1 1
    CAPNS1 RANBP17 0 0 0 154 1 1
    CAPNS1 HRAS 0 0 113 163 1 1
    CAPNS1 CTNNB1 0 0 218 222 1 1
    CAPNS1 KIRREL2 0 0 103 492 1 1
    CAPNS1 CAPN5 0 600 596 900 1 1
    CAPNS1 PSMC2 0 0 181 222 1 1
    CAPNS1 MLF2 0 0 0 235 1 1
    CAPNS1 HCLS1 0 0 241 487 1 1
    CAPNS1 MPHOSPH6 0 0 193 193 1 1
    CAPNS1 ARF3 0 0 0 165 1 1
    CAPNS1 CTSL 0 0 166 293 1 1
    CAPNS1 NFKBID 0 0 68 528 1 1
    CAPNS1 MAPK13 0 0 0 153 1 1
    CAPNS1 RPL9 0 0 160 212 1 1
    CAPNS1 VAT1 0 0 202 244 1 1
    CAPNS1 MAPRE1 0 0 209 225 1 1
    CAPNS1 MAP3K2 0 0 241 279 1 1
    CAPNS1 NUDCD1 270 0 0 270 1 1
    CAPNS1 ACAN 0 0 61 157 1 1
    CAPNS1 ACTN4 0 0 108 372 1 1
    CAPNS1 KRT12 0 0 218 218 1 1
    CAPNS1 ACTR2 0 0 139 250 1 1
    CAPNS1 TRA2A 0 0 128 220 1 1
    CAPNS1 NANS 0 0 116 194 1 1
    CAPNS1 EEF1B2 0 0 119 189 1 1
    CAPNS1 GCA 0 0 640 200 1 1
    CAPNS1 LRRC31 0 0 184 183 1 1
    CAPNS1 RRAS 0 0 90 229 1 1
    CAPNS1 DCTN2 0 0 71 165 1 1
    CAPNS1 ANXA11 0 0 95 177 1 1
    CAPNS1 PSMC6 0 0 0 216 1 1
    CAPNS1 ATP5D 0 0 0 198 1 1
    CAPNS1 PSMB4 0 0 114 230 1 1
    CAPNS1 RAD23A 0 0 0 155 1 1
    CAPNS1 SLC25A6 0 0 62 195 1 1
    CAPNS1 TAGLN 0 0 103 214 1 1
    CAPNS1 AMOTL1 0 0 0 286 1 1
    CAPNS1 LAMTOR5 0 0 206 206 1 1
    CAPNS1 CLPTM1 0 0 0 203 1 1
    CAPNS1 ANXA5 0 0 211 269 1 1
    CAPNS1 NPM2 0 0 91 170 1 1
    CAPNS1 TEF 0 0 73 275 1 1
    CAPNS1 COMMD9 0 0 173 213 1 1
    CAPNS1 GRIA2 0 0 108 169 1 1
    CAPNS1 MYT1L 0 0 58 158 1 1
    CAPNS1 PIANP 0 0 48 253 1 1
    CAPNS1 IQGAP1 0 0 170 181 1 1
    CAPNS1 CLEC4D 0 0 0 151 1 1
    CAPNS1 EIF1B 0 0 125 377 1 1
    CAPNS1 ARF1 0 0 74 180 1 1
    CAPNS1 COTL1 0 0 165 241 1 1
    CAPNS1 CKAP5 0 0 67 165 1 1
    CAPNS1 NSG1 0 0 108 351 1 1
    CAPNS1 ARHGEF6 213 0 831 861 1 1
    CAPNS1 MAPK4 0 0 0 169 1 1
    CAPNS1 SDF4 0 0 92 169 1 1
    CAPNS1 CIDEC 0 0 49 294 1 1
    CAPNS1 MYH3 0 0 134 196 1 1
    CAPNS1 ASCL5 0 0 235 235 1 1
    CAPNS1 APC 0 0 0 167 1 1
    CAPNS1 GAPDH 129 0 243 468 1 2
    CAPNS1 PML 0 0 0 170 1 1
    CAPNS1 ENO1 0 0 187 255 1 1
    CAPNS1 EPC2 0 0 116 181 1 1
    CAPNS1 CAPZA1 0 0 108 218 1 1
    CAPNS1 MANEA 0 0 134 206 1 1
    CAPNS1 RAN 0 0 54 169 1 1
    CAPNS1 CAPN15 0 600 450 816 1 1
    CAPNS1 KIRREL3 0 0 0 188 1 1
    CAPNS1 ANAPC5 0 0 105 187 1 1
    CAPNS1 KCNIP4 0 0 122 155 1 1
    CAPNS1 DERA 0 0 137 199 1 1
    CAPNS1 ALDOA 0 0 0 230 1 1
    CAPNS1 GLDC 0 0 71 235 1 1
    CAPNS1 HS6ST1 0 0 136 490 1 1
    CAPNS1 C6orf58 0 0 285 284 1 1
    CAPNS1 EFTUD2 120 0 0 179 1 1
    CAPNS1 P4HB 0 0 88 304 1 2
    CAPNS1 TAX1BP3 0 0 0 154 1 1
    CAPNS1 ASNA1 0 0 194 261 1 1
    CAPNS1 DDX47 0 0 108 261 1 1
    CAPNS1 ILK 0 0 114 236 1 1
    CAPNS1 TLN1 0 900 435 945 1 1
    CAPNS1 WFS1 0 0 0 168 1 1
    CAPNS1 APEX1 129 0 45 152 1 1
    CAPNS1 MYC 0 0 151 150 1 2
    CAPNS1 HMGCLL1 0 0 151 150 1 1
    CAPNS1 CAPN13 0 600 469 727 1 1
    CAPNS1 CAPN3 0 600 842 761 1 1
    CAPNS1 PLTP 0 0 66 248 1 1
    CAPNS1 CTSV 0 0 139 270 1 1
    CAPNS1 PSMB3 0 0 166 197 1 1
    CAPNS1 PSMA6 0 0 147 205 1 1
    CAPNS1 SSR4 0 0 99 179 1 1
    CAPNS1 CMIP 0 0 93 219 1 1
    CAPNS1 TBCB 245 0 0 477 1 1
    CAPNS1 UBA1 128 0 0 269 1 1
    CAPNS1 TTN 0 0 150 198 1 1
    CAPNS1 FLNA 0 0 218 259 1 1
    CAPNS1 FLII 0 0 0 209 1 1
    CAPNS1 ANAPC11 0 0 82 225 1 1
    CAPNS1 LRFN3 0 0 149 496 1 1
    CAPNS1 ACTA1 0 900 91 913 1 1
    CAPNS1 CAPZB 0 0 142 279 1 1
    CAPNS1 RPS25 0 0 119 155 1 1
    CAPNS1 SRI 0 0 720 210 1 1
    CAPNS1 RPL28 0 0 91 176 1 1
    CAPNS1 PEF1 0 0 764 340 1 1
    CAPNS1 PTPRD 0 0 49 265 1 1
    CAPNS1 LMNA 0 0 170 212 1 1
    CAPNS1 CARHSP1 0 0 108 239 1 1
    CAPNS1 CTSA 0 0 0 233 1 1
    CAPNS1 MYL6 0 0 47 197 1 1
    CAPNS1 NGEF 0 0 145 520 1 1
    CAPNS1 CAPNS2 674 300 455 765 1 1
    CAPNS1 ATP6V0C 0 0 0 249 1 2
    CAPNS1 RASGRP1 0 0 47 193 1 1
    CAPNS1 DCN 0 0 137 172 1 2
    CAPNS1 TP53 0 0 157 156 1 2
    CAPNS1 LRIG1 0 0 144 160 1 1
    CAPNS1 EGFR 0 0 154 153 1 1
    CAPNS1 FFAR1 0 0 49 308 1 1
    CAPNS1 STAU1 0 0 114 263 1 1
    CAPNS1 RHPN1 0 0 0 205 1 1
    CAPNS1 MCOLN1 0 0 108 376 1 1
    CAPNS1 PHKB 0 0 141 270 1 1
    CAPNS1 GABPB2 0 0 181 186 1 1
    CAPNS1 ETNK1 0 0 103 338 1 1
    CAPNS1 ADAM9 0 0 57 160 1 1
    CAPNS1 STAT3 111 0 112 206 1 2
    CAPNS1 ATP6V0D1 0 0 57 199 1 1
    CAPNS1 DLGAP1 0 0 67 283 1 1
    CAPNS1 PTPN22 0 0 46 159 1 1
    CAPNS1 PDCD6 0 0 646 216 1 1
    CAPNS1 SLURP1 0 0 350 349 1 1
    CAPNS1 CISD2 0 0 112 173 1 2
    CAPNS1 ATP2B4 0 0 0 158 1 1
    CAPNS1 MED23 0 0 73 228 1 1
    CAPNS1 HUWE1 270 0 0 296 1 1
    CAPNS1 RBM42 0 0 0 265 1 1
    CAPNS1 ELMO1 0 0 54 152 1 1
    CAPNS1 TECR 0 0 0 208 1 1
    CAPNS1 LGALS1 0 0 60 150 1 1
    CAPNS1 CDK5 0 650 138 697 1 2
    CAPNS1 SERPINF1 0 0 59 155 1 1
    CAPNS1 HVCN1 0 0 0 234 1 1
    CAPNS1 FAM153C 0 0 248 248 1 1
    CAPNS1 CASQ2 0 0 63 177 1 1
    CAPNS1 SPARC 128 0 0 164 1 1
    CAPNS1 CELA2A 0 500 0 499 1 1
    CAPNS1 FBLN1 0 0 63 160 1 1
    CAPNS1 ANXA8 0 0 166 179 1 1
    CAPNS1 ARPC1A 0 0 136 210 1 1
    CAPNS1 PLS3 0 0 107 176 1 1
    CAPNS1 KNG1 178 0 0 177 1 1
    CAPNS1 GNB2 64 0 0 253 1 1
    CAPNS1 CAMK2N1 0 0 167 173 1 1
    CAPNS1 XPO7 0 0 0 185 1 1
    CAPNS1 CAPN6 0 600 764 937 1 1
    CAPNS1 ARPC1B 0 0 74 207 1 1
    CAPNS1 CASP7 0 0 134 157 1 1
    CAPNS1 C1orf122 0 0 323 391 1 1
    CAPNS1 ITGB1 0 900 113 913 1 1
    CAPNS1 NYX 0 0 123 323 1 1
    CAPNS1 ANXA3 0 0 108 150 1 1
    CAPNS1 REXO2 0 0 181 463 1 1
    CAPNS1 ZYX 0 0 155 271 1 1
    CAPNS1 FBXO9 0 0 113 168 1 1
    CAPNS1 TSC22D1 0 0 93 232 1 1
    CAPNS1 BSG 0 0 0 191 1 1
    CAPNS1 CPTP 0 0 155 185 1 1
    CAPNS1 FAM227A 0 0 108 169 1 1
    CAPNS1 PPP1CB 0 0 167 326 1 1
    CAPNS1 ACTR1B 0 0 0 212 1 1
    CAPNS1 PSMB2 0 0 95 167 1 1
    CAPNS1 DNM2 0 0 0 165 1 1
    CAPNS1 DDX41 0 0 0 183 1 1
    CAPNS1 BLMH 0 0 90 263 1 1
    CAPNS1 HSPA14 0 0 79 150 1 1
    CAPNS1 YWHAG 129 0 101 226 1 1
    CAPNS1 HYOU1 0 0 100 248 1 1
    CAPNS1 SEC31B 0 0 0 179 1 1
    CAPNS1 TPM4 0 0 113 207 1 1
    CAPNS1 CDH1 0 900 122 908 1 1
    CAPNS1 SDSL 0 0 137 169 1 1
    CAPNS1 MAGEA3 270 0 0 270 1 2
    CAPNS1 AMOT 0 0 56 467 1 1
    CAPNS1 PTK2 0 900 216 918 1 1
    CAPNS1 RUVBL1 271 0 0 271 1 1
    CAPNS1 KCNS3 0 0 122 176 1 1
    CAPNS1 MYLPF 0 0 127 178 1 1
    CAPNS1 CAPZA2 0 0 195 257 1 1
    CAPNS1 MAP2K4 0 0 66 163 1 1
    CAPNS1 GLRX3 0 0 95 159 1 1
    CAPNS1 GOLGA3 0 0 123 356 1 1
    CAPNS1 IMPDH1 0 0 73 196 1 1
    CAPNS1 SRL 0 0 123 358 1 1
    CAPNS1 PXN 0 900 163 916 1 1
    CAPNS1 DIABLO 128 0 82 195 1 1
    CAPNS1 RHPN2 0 0 0 205 1 1
    CAPNS1 TPM2 0 0 108 218 1 1
    CAPNS1 GPX4 0 0 66 250 1 1
    CAPNS1 POLR2L 0 0 66 206 1 1
    CAPNS1 IL2RG 192 0 0 192 1 1
    CAPNS1 FLG 0 900 0 900 1 1
    CAPNS1 CTGF 0 0 52 195 1 1
    CAPNS1 POLR2E 0 0 0 181 1 1
    CAPNS1 ARL6IP5 0 0 92 167 1 1
    CAPNS1 GNAS 0 0 64 161 1 1
    CAPNS1 HSP90B1 0 0 135 194 1 1
    CAPNS1 ITGA1 0 900 0 900 1 1
    CAPNS1 NACC1 0 0 117 489 1 1
    CAPNS1 SLIT1 0 0 54 153 1 1
    CAPNS1 EPS15L1 0 0 97 195 1 1
    CAPNS1 SNCA 0 0 306 306 1 2
    CAPNS1 MVP 0 0 161 241 1 1
    CAPNS1 FFAR2 0 0 45 305 1 1
    CAPNS1 MST4 245 0 0 270 1 1
    CAPNS1 DPYSL2 0 0 90 247 1 1
    CAPNS1 MAPK12 0 0 0 153 1 1
    CAPNS1 PYGB 0 0 128 164 1 1
    CAPNS1 ACTR3 0 0 251 317 1 1
    CAPNS1 TNKS 0 0 45 191 1 1
    CAPNS1 ERGIC3 0 0 0 194 1 1
    CAPNS1 COPE 0 0 0 243 1 1
    CAPNS1 JUN 0 0 151 158 1 1
    CAPNS1 CASQ1 0 0 94 298 1 1
    CAPNS1 VCP 0 0 122 181 1 2
    CAPNS1 CAPN2 871 900 905 995 1 2
    CAPNS1 RPL4 0 0 112 151 1 1
    CAPNS1 YWHAE 218 0 172 349 1 1
    CAPNS1 GRN 0 0 0 189 1 1
    CAPNS1 ZNF90 0 0 164 163 1 1
    CAPNS1 GRB2 242 0 0 296 1 1
    CAPNS1 FKBP3 0 0 96 167 1 1
    CAPNS1 SMC3 0 0 43 171 1 1
    CAPNS1 TSPYL1 0 0 123 155 1 1
    CAPNS1 TAGLN3 0 0 0 167 1 1
    CAPNS1 CALR 0 0 123 175 1 1
    CAPNS1 TGIF2-C20orf24 0 0 294 319 1 1
    CAPNS1 CLIP4 0 0 0 269 1 1
    CAPNS1 LIN37 0 0 108 550 1 1
    CAPNS1 ATP5B 0 0 202 241 1 1
    CAPNS1 FBXO36 0 0 210 289 1 1
    CAPNS1 VTA1 0 0 91 174 1 1
    CAPNS1 MAT2A 129 0 0 233 1 1
    CAPNS1 WFDC2 0 0 73 231 1 1
    CAPNS1 MMP2 0 0 225 243 1 1
    CAPNS1 CPSF6 0 0 134 370 1 1
    CAPNS1 EHD4 0 0 112 183 1 1
    CAPNS1 OSTF1 0 0 0 286 1 1
    CAPNS1 SPP1 0 0 123 155 1 1
    CAPNS1 VPS28 0 0 0 283 1 1
    CAPNS1 GPAA1 0 0 0 181 1 1
    CAPNS1 HSPA8 0 0 156 169 1 2
    CAPNS1 OVOL3 0 0 88 152 1 1
    CAPNS1 RHOA 0 900 151 919 1 1
    CAPNS1 GSN 0 0 157 176 1 1
    CAPNS1 MYL1 0 0 91 229 1 1
    CAPNS1 TPM1 0 0 112 153 1 1
    CAPNS1 EIF5 129 0 0 240 1 1
    CAPNS1 TIMP1 0 0 95 216 1 1
    CAPNS1 RAB1A 43 0 74 194 1 2
    CAPNS1 RHOG 0 0 0 152 1 1
    CAPNS1 RPL8 0 0 112 164 1 1
    CAPNS1 ADAD1 0 0 99 161 1 1
    CAPNS1 MYH9 0 0 104 171 1 1
    CAPNS1 NIPSNAP3A 0 0 204 289 1 1
    CAPNS1 AKAP9 0 0 71 269 1 1
    CAPNS1 PROSC 129 0 0 425 1 1
    CAPNS1 SEC31A 0 0 0 179 1 1
    CAPNS1 GPR42 0 0 0 451 1 1
    CAPNS1 KIF5A 0 0 67 210 1 1
    CAPNS1 LASP1 0 0 95 189 1 1
    CAPNS1 ALDOB 0 0 60 163 1 1
    CAPNS1 S100A11 0 0 142 205 1 1
    CAPNS1 ACTN3 0 0 74 159 1 1
    CAPNS1 SYT1 0 0 115 188 1 1
    CAPNS1 ALDH3A1 0 0 149 181 1 1
    CAPNS1 ACTB 0 0 250 372 1 1
    CAPNS1 MSN 0 0 90 404 1 1
    CAPNS1 RNASEK 0 0 0 211 1 1
    CAPNS1 STUB1 0 0 0 263 1 2
    CAPNS1 CTTN 0 0 85 195 1 1
    CAPNS1 ARHGDIA 0 0 205 446 1 1
    CAPNS1 MAPK3 0 900 126 929 1 2
    CAPNS1 SARAF 0 0 108 201 1 1
    CAPNS1 EXOC6B 0 0 90 190 1 1
    CAPNS1 MYL12B 0 0 54 171 1 1
    CAPNS1 DTD2 0 0 209 212 1 1
    CAPNS1 ANXA4 0 0 134 172 1 1
    CAPNS1 CAPN12 0 600 459 713 1 1
    CAPNS1 NIPBL 0 0 54 198 1 1
    CAPNS1 SQSTM1 0 0 134 211 1 2
    CAPNS1 MYBPC1 0 0 142 167 1 1
    CAPNS1 APLP2 0 0 0 215 1 1
    CAPNS1 PITPNB 0 0 162 347 1 1
    CAPNS1 ZBTB7C 0 0 54 159 1 1
    CAPNS1 ALG2 0 0 0 190 1 1
    CAPNS1 GDA 0 0 188 204 1 1
    CAPNS1 AES 0 0 0 177 1 1
    CAPNS1 TGFB1 0 0 99 188 1 1
    CAPNS1 USP1 270 0 84 302 1 1
    CAPNS1 SEC13 0 0 0 183 1 1
    CAPNS1 PNP 0 0 122 157 1 1
    CAPNS1 WWP2 270 0 0 270 1 1
    CAPNS1 MYO1E 245 0 0 244 1 1
    CAPNS1 TRUB1 0 0 154 235 1 1
    CAPNS1 PAK1IP1 0 0 128 213 1 1
    CAPNS1 JDP2 0 0 69 226 1 1
    CAPNS1 TRIM28 0 0 0 172 1 2
    CAPNS1 CAMK2D 0 0 129 166 1 1
    CAPNS1 RPP40 0 0 134 225 1 1
    CAPNS1 ECH1 128 0 100 276 1 1
    CAPNS1 DTD1 0 0 59 215 1 1
    CAPNS1 EED 0 0 0 181 1 1
    CAPNS1 SRC 0 900 158 917 1 1
    CAPNS1 PSMG4 0 0 142 159 1 1
    CAPNS1 TUBA1C 0 0 249 286 1 1
    CAPNS1 WARS2 0 0 108 216 1 1
    CAPNS1 CDC42 0 0 150 250 1 1
    CAPNS1 RPS8 0 0 138 295 1 1
    CAPNS1 SHISA5 0 0 0 180 1 1
    CAPNS1 SPTAN1 0 900 321 930 1 1
    CAPNS1 CEMIP 0 0 451 457 1 1
    CAPNS1 YWHAB 0 0 180 197 1 1
    CAPNS1 FOXO3 0 0 148 166 1 2
    CAPNS1 KDM6A 0 0 0 195 1 1
    CAPNS1 OGFOD1 129 0 0 425 1 1
    CAPNS1 ILF2 0 0 123 214 1 1
    CAPNS1 TGFBI 0 0 218 272 1 1
    CAPNS1 TPM3 0 0 68 218 1 1
    CAPNS1 SLIT3 0 0 0 273 1 1
    CAPNS1 AIFM1 0 0 207 207 1 1
    CAPNS1 DSTN 0 0 74 293 1 1
    CAPNS1 CLEC12B 0 0 143 317 1 1
    CAPNS1 PTPN23 0 0 0 238 1 1
    CAPNS1 HSP90AB1 0 0 134 186 1 2
    CAPNS1 RBBP5 0 0 0 188 1 1
    CAPNS1 ERI3 0 0 163 232 1 1
    CAPNS1 HLCS 0 0 97 484 1 1
    CAPNS1 RHOC 0 0 0 231 1 1
    CAPNS1 RAB21 0 0 0 207 1 1
    CAPNS1 GPR107 0 0 0 436 1 1
    CAPNS1 MYOF 0 0 329 344 1 1
    CAPNS1 RALY 0 0 0 177 1 1
    CAPNS1 RPL29 0 0 95 186 1 1
    CAPNS1 TCAP 0 0 72 241 1 1
    CAPNS1 SLC12A6 0 0 88 328 1 1
    CAPNS1 KRT6A 0 0 74 171 1 1
    CAPNS1 PPP2R4 0 0 74 165 1 1
    CAPNS1 ATL2 0 0 108 303 1 1
    CAPNS1 ASNS 245 0 0 485 1 1
    CAPNS1 RPL35 0 0 170 191 1 1
    CAPNS1 GDI2 0 0 241 266 1 1
    CAPNS1 DNAJB14 0 0 141 200 1 1
    CAPNS1 TPT1 0 0 231 247 1 1
    CAPNS1 CAPN1 791 900 983 988 1 2
    CAPNS1 AKT1 0 0 235 292 1 2
    CAPNS1 PPP1R13L 0 0 136 190 1 1
    CAPNS1 DYSF 0 0 229 271 1 1
    CAPNS1 AP2M1 0 0 0 366 1 1
    CAPNS1 TWF2 0 0 42 208 1 1
    CAPNS1 CAP1 0 0 66 156 1 1
    CAPNS1 SIPA1 0 0 0 174 1 1
    CAPNS1 SLC16A2 0 0 0 190 1 1
    CAPNS1 EEF2 0 0 537 562 1 1
    CAPNS1 C8orf37 169 0 0 169 1 1
    CAPNS1 SDHAF1 0 0 107 350 1 1
    CAPNS1 FIS1 0 0 0 159 1 2
    CAPNS1 TCP11 0 0 127 181 1 1
    CAPNS1 VCL 0 0 175 175 1 1
    CAPNS1 TMEM147 0 0 0 195 1 1
    CAPNS1 PDCD6IP 0 0 71 254 1 1
    CAPNS1 ALDH7A1 245 0 0 486 1 1
    CAPNS1 CHMP2A 0 0 0 192 1 2
    CAPNS1 DAGLA 0 0 0 156 1 1
    CAPNS1 USP5 0 0 0 164 1 1
    CAPNS1 GNAI2 0 0 0 324 1 1
    CAPNS1 LPIN2 0 0 67 448 1 1
    CAPNS1 HMG20A 0 0 123 361 1 1
    CAPNS1 TNF 220 0 108 274 1 1
    CAPNS1 CDC42BPB 0 0 128 151 1 1
    CAPNS1 PIH1D1 120 0 0 153 1 1
    CAPNS1 UQCRC1 0 0 0 297 1 1
    CAPNS1 DMPK 0 0 108 407 1 1
    CAPNS1 PAFAH1B1 129 0 0 185 1 1
    CAPNS1 CNPPD1 0 0 242 294 1 1
    CAPNS1 PTMA 129 0 77 161 1 1
    CAPNS1 PPP2R1A 0 0 0 248 1 1
    CAPNS1 MAPK1 0 900 49 924 1 2
    CAPNS1 SYNE1 0 0 45 205 1 1
    CAPNS1 PKM 0 0 61 178 1 1
    CAPNS1 ARPC3 0 0 0 174 1 1
    CAPNS1 GSTM5 0 0 141 162 1 1
    CAPNS1 FFAR3 0 0 53 457 1 1
    CAPNS1 AGTRAP 213 0 0 213 1 1
    CAPNS1 RAB1B 0 0 0 219 1 2
    CAPNS1 APBA1 0 0 62 317 1 1
    CAPNS1 PRPF8 0 0 120 179 1 1
    CAPNS1 RAB7A 0 0 67 150 1 2
    CAPNS1 PRDX4 0 0 165 216 1 1
    CAPNS1 PRDX2 0 0 171 226 1 1
    CAPNS1 SYPL1 0 0 134 308 1 1
    CAPNS1 GSTP1 0 0 128 255 1 1
    CAPNS1 SRPR 0 0 272 380 1 1
    CAPNS1 ALDH2 128 0 0 161 1 1
    CAPNS1 CCND1 0 0 135 150 1 1
    CAPNS1 CSRP2BP 0 0 53 199 1 1
    CAPNS1 CAPN11 0 600 767 763 1 1
    CAPNS1 STON2 0 0 108 200 1 1
    CAPNS1 ACTN1 0 0 184 229 1 1
    CAPNS1 ATP6V1F 0 0 66 162 1 1
    CAPNS1 ANXA2 0 0 244 302 1 1
    CAPNS1 SMYD1 274 0 0 274 1 1
    CAPNS1 STIM1 0 0 134 157 1 2
    CAPNS1 EHD3 0 0 0 169 1 1
    CAPNS1 YWHAQ 129 0 75 213 1 1
    CAPNS1 DAGLB 0 0 0 156 1 1
    CAPNS1 PSMA3 0 0 112 152 1 1
    CAPNS1 TESK1 0 0 102 208 1 1
    CAPNS1 NDUFA10 0 0 167 167 1 1
    CAPNS1 RASA1 413 0 45 427 1 1
    CAPNS1 FH 128 0 0 160 1 1
    CAPNS1 CAST 462 800 806 986 1 1
    CAPNS1 DDI2 0 0 147 236 1 1
    CAPNS1 LCP1 0 0 113 152 1 1
    CAPNS1 CANX 0 0 136 207 1 2
    CAPNS1 POU5F1 270 0 0 270 1 1
    CAPNS1 ARPC4 0 0 84 254 1 1
    CAPNS1 POLR2I 0 0 96 557 1 1
    CAPNS1 PITPNA 0 0 69 185 1 1
    CAPNS1 MAP2K2 0 0 44 154 1 1
    CAPNS1 CHIT1 0 0 78 218 1 1
    CAPNS1 CAPN14 0 600 325 731 1 1
    CAPNS1 MLC1 0 900 0 900 1 1
    CAPNS1 CORO1B 0 0 0 198 1 1
    CAPNS1 CAPN7 0 600 600 872 1 1
    CAPNS1 PTH1R 0 0 441 441 1 1
    CAPNS1 MAPK14 0 0 60 240 1 1
    CAPNS1 TIMP3 0 0 125 185 1 1
    CAPNS1 CNTN2 0 0 62 159 1 1
    CAPNS1 CFL1 0 0 195 305 1 1
    CAPNS1 WDR1 0 0 0 244 1 1
    CAPNS1 CPNE4 0 0 134 190 1 1
    CAPNS1 UBE2M 0 0 0 170 1 1
    CAPNS1 SUSD5 0 0 166 392 1 1
    CAPNS1 KERA 0 0 181 196 1 1
    CAPNS1 EFHD2 0 0 0 152 1 1
    CAPNS1 CLIC4 0 0 162 166 1 1
    CAPNS1 ISOC1 245 0 0 244 1 1
    CAPNS1 SMNDC1 0 0 113 186 1 1
    CAPNS1 G6PC3 0 0 0 178 1 1
    CAPNS1 IARS2 128 0 74 158 1 1
    CAPNS1 DNM1L 0 0 101 168 1 2
    CAPNS1 SERPINF2 0 0 0 258 1 1
    CAPNS1 FTL 0 0 107 182 1 1
    CAPNS1 RAB5C 0 0 0 162 1 1
    CAPNS1 MAPK7 0 0 0 153 1 1
    CAPNS1 ACSL4 0 0 95 190 1 1
    CAPNS1 VEGFA 0 0 150 168 1 1
    CAPNS1 ACTR1A 0 0 123 427 1 1
    CAPNS1 SNX17 0 0 0 179 1 1
    CAPNS1 PIEZO1 0 0 87 353 1 1
    CAPNS1 CLIP3 0 0 172 485 1 1
    CAPNS1 ACTG1 0 0 150 214 1 1
    CAPNS1 TF 0 0 167 167 1 1
    CAPNS1 MARCKS 0 0 171 201 1 1
    CAPNS1 POF1B 0 0 45 221 1 1
    CAPNS1 ALDH1B1 128 0 0 161 1 1
    CAPNS1 GOT2 0 0 58 183 1 1
    CAPNS1 NRGN 270 0 60 284 1 1
    CAPNS1 DAP 0 0 0 201 1 2
    CAPNS1 FERMT2 129 0 0 231 1 1
    CAPNS1 SHC1 341 0 0 365 1 1
    CAPNS1 EZR 0 900 156 917 1 1
    CAPNS1 CTSD 0 0 219 309 1 2
    CAPNS1 TYRO3 0 0 295 295 1 1
    CAPNS1 RAD51B 0 0 46 226 1 1
    CAPNS1 AP2S1 0 0 0 438 1 1
    CAPNS1 FN1 74 0 180 208 1 1
    CAPNS1 MT-CYB 0 0 49 610 1 1
    CAPNS1 HNRNPK 0 0 145 160 1 1
    CAPNS1 STMN1 0 0 168 167 1 1
    CAPNS1 ACVRL1 0 0 62 265 1 1
    CAPNS1 RPS18 0 0 0 207 1 1
    CAPNS1 TBCA 0 0 52 151 1 1
    CAPNS1 SH3BGRL3 0 0 0 561 1 1
    CAPNS1 LAMA1 0 0 436 436 1 1
    CAPNS1 ANXA6 0 0 142 285 1 1
    CAPNS1 HSPB1 0 0 203 255 1 1
    CAPNS1 RBBP9 0 0 46 193 1 1
    CAPNS1 TSG101 0 0 0 215 1 2
    CAPNS1 COX7A1 0 0 125 510 1 1
    CAPNS1 WDR90 0 0 0 176 1 1
    CAPNS1 PTPN1 0 0 123 167 1 1
    CAPNS1 HIPK2 0 0 61 175 1 1
    CAPNS1 DPYSL3 0 0 67 317 1 1
    CAPNS1 RAC1 0 900 61 906 1 1
    CAPNS1 TXNDC5 0 0 77 154 1 1
    CAPNS1 PPP1CA 244 0 60 527 1 1
    CAPNS1 EIF5A 0 0 358 422 1 1
    CAPNS1 TUBB 0 0 230 229 1 1
    CAPNS1 RNH1 0 0 0 187 1 1
    CAPNS1 LARP4 0 0 0 157 1 1
    CAPNS1 TLE3 0 0 66 320 1 1
    CAPNS1 SFXN3 0 0 0 157 1 1
    CAPNS1 SERBP1 0 0 107 308 1 1
    CAPNS1 CTSB 0 0 155 154 1 2
    CAPNS1 ANXA1 0 0 155 205 1 1
    CAPNS1 PRKCSH 0 0 0 213 1 1
    CAPNS1 ARL4C 0 0 97 301 1 1
    CAPNS1 LEPROTL1 0 0 123 361 1 1
    CAPNS1 PGLS 0 0 0 195 1 1
    CAPNS1 MAPT 0 0 296 321 1 2
    CAPNS1 POLR3F 0 0 46 208 1 1
    CAPNS1 ELAVL4 0 0 51 153 1 1
    CAPNS1 WARS 0 0 0 185 1 1
    CAPNS1 EMC1 270 0 0 270 1 1
    CAPNS1 MAPK11 0 0 0 248 1 1
    CAPNS1 PEA15 0 0 76 170 1 1
    CAPNS1 DNAJC10 0 0 75 230 1 1
    CAPNS1 CAPG 0 0 143 183 1 1
    CAPNS1 ERRFI1 0 0 123 215 1 1
    CAPNS1 ACADVL 0 0 306 347 1 1
    CAPNS1 ADGB 0 0 64 252 1 1
    CAPNS1 SLC41A1 0 0 95 205 1 1
    CAPNS1 GNAI3 129 0 0 227 1 2
    CAPNS1 CSPG4 271 0 0 271 1 1
    CAPNS1 MALRD1 0 0 67 235 1 1
    CAPNS1 PDIA3 0 0 193 215 1 1
    CAPNS1 CLIC1 0 0 167 247 1 1
    CAPNS1 DAD1 0 0 134 196 1 1
    CAPNS1 CAPN9 0 600 774 773 1 1
    CAPNS1 PSMD2 0 0 92 174 1 1
    CAPNS1 CDK5R1 0 900 0 900 1 1
    CAPNS1 APLP1 0 0 85 558 1 1
    CAPNS1 YWHAZ 129 0 113 452 1 1
    CAPNS1 CNDP2 0 0 167 185 1 1
    CAPNS1 HM13 0 0 87 189 1 1
    CAPNS1 ANKRD40 0 0 0 179 1 1
    CAPNS1 FTH1 0 0 213 246 1 1
    CAPNS1 RABAC1 0 0 0 204 1 1
    CAPNS1 MYH13 0 0 94 156 1 1
    CAPNS1 NRAS 0 0 67 159 1 1
    CAPNS1 CASP14 0 500 0 513 1 1
    CAPNS1 KIRREL 0 0 0 284 1 1
    CAPNS1 HSPA5 0 0 150 188 1 2
    CAPNS1 TKT 0 0 107 152 1 1
    CAPNS1 CORO1C 0 0 139 157 1 1
    CAPNS1 DCPS 129 0 0 231 1 1
    CAPNS1 CAPN8 0 600 470 761 1 1
    CAPNS1 SYNCRIP 0 0 60 240 1 1
    CAPNS1 UEVLD 0 0 0 181 1 1
    CAPNS1 TAGLN2 0 0 102 285 1 1
    CAPNS1 RPS4X 0 0 103 198 1 1
    CAPNS1 ENSG00000276418 0 0 122 171 1 1
    CAPNS1 PTGR2 0 0 123 187 1 1
    CAPNS1 ERCC1 0 0 0 151 1 1
    CAPNS1 CAPN10 0 600 502 834 1 2
    CAPNS1 PFN1 0 0 0 316 1 1
    CAPNS1 IL1RAP 0 0 95 162 1 1
    CAPNS1 KIFAP3 0 0 81 173 1 1
    CAPNS1 PDIA4 261 0 0 292 1 1
    CAPNS1 DNAJA2 0 0 162 248 1 1
    CAPNS1 BANF1 0 0 0 216 1 1
    CAPNS1 YIF1B 0 0 143 203 1 1
    CAPNS1 PTGES3 0 0 107 245 1 1
    CAPNS1 CKB 0 0 148 214 1 1
    CAPNS1 YWHAH 245 0 123 352 1 1
    CAPNS1 PRODH2 0 0 167 430 1 1
    CAPNS1 PSMB6 0 0 90 154 1 1
    CAPNS1 MMP14 0 0 91 252 1 1
    CAPNS1 ARPC5 0 0 271 408 1 1
    CAPNS1 CTSZ 0 0 123 155 1 1
    CAPNS1 PDIA6 0 0 116 152 1 1
    CAPNS1 CASP3 0 600 261 700 1 2
    CAPNS1 TGFBR3 0 0 52 198 1 1
    CAPNS1 EEF1A1 0 0 150 203 1 1
    CAPNS1 PRELID1 0 0 0 183 1 1
    CAPNS1 GPR108 0 0 143 694 1 1
    CAPNS1 PSMA5 0 0 74 258 1 1
    CAPNS1 RPL31 0 0 82 328 1 1
    CAPNS1 KLK5 0 500 0 499 1 1
    CAPNS1 TIPARP 0 0 66 164 1 1
    CAPNS1 COL6A2 0 0 217 217 1 1
    CAPNS1 SEPT7 0 0 67 150 1 1
    CAPNS1 PSMC4 0 0 193 283 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005509 Molecular Function calcium ion binding enables IEA
    GO:0004198 Molecular Function calcium-dependent cysteine-type endopeptidase activity enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0008284 Biological Process positive regulation of cell population proliferation involved_in TAS
    GO:0006508 Biological Process proteolysis involved_in NAS
    GO:0016241 Biological Process regulation of macroautophagy involved_in NAS
    GO:0110158 Cellular Component calpain complex part_of IBA
    GO:0110158 Cellular Component calpain complex part_of IPI
    GO:0110158 Cellular Component calpain complex part_of ISS
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in TAS
    Pathways
    Name DB ID
    Developmental Biology Reactome R-HSA-1266738
    Degradation of the extracellular matrix Reactome R-HSA-1474228
    Extracellular matrix organization Reactome R-HSA-1474244
    Disease Reactome R-HSA-1643685
    Keratinization Reactome R-HSA-6805567
    Formation of the cornified envelope Reactome R-HSA-6809371
    Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Reactome R-HSA-8862803
    Neurodegenerative Diseases Reactome R-HSA-8863678
    Diseases of programmed cell death Reactome R-HSA-9645723
    Defective Intrinsic Pathway for Apoptosis Reactome R-HSA-9734009
    Integrin-mediated cell adhesion (WP185) WikiPathways WP185_r116785
    Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001302632 2 mRNA transcript variant 3 NC_000019 Reference
    XM_005259295 2 mRNA transcript variant X1 NC_000019 Reference
    NM_001749 4 mRNA transcript variant 1 NC_000019 Reference
    XM_005259296 2 mRNA transcript variant X2 NC_000019 Reference
    NM_001003962 3 mRNA transcript variant 2 NC_000019 Reference
    NM_001302633 2 mRNA transcript variant 4 NC_000019 Reference
    XM_011527359 2 mRNA transcript variant X3 NC_000019 Reference