BOK

BCL2 family apoptosis regulator BOK
General Information
Name BCL2 family apoptosis regulator BOK
Alias
  • bcl-2-related ovarian killer protein
  • BCL2 related ovarian killer
  • BOK, BCL2 family apoptosis regulator
  • bcl-2-like protein 9
  • bcl2-L-9
  • hBOK
Synonyms BCL2L9 BOKL MGC4631
Gene_family BCL2 family
organism Homo sapiens
entrez_id 666
location 2q37.3
transcript_count 7
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family. [provided by RefSeq, Sep 2011]
      Stringdb Bcl-2-related ovarian killer protein; Isoform 1: Apoptosis regulator that functions through different apoptotic signaling pathways. Plays a roles as pro-apoptotic protein that positively regulates intrinsic apoptotic process in a BAX- and BAK1-dependent manner or in a BAX- and BAK1-independent manner. In response to endoplasmic reticulum stress promotes mitochondrial apoptosis through downstream BAX/BAK1 activation and positive regulation of PERK-mediated unfolded protein response (By similarity). Activates apoptosis independently of heterodimerization with survival- promoting BCL2 and [...]
      nextProt Pro-apoptotic molecule exerting its function through the mitochondrial pathway.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    BOK BioGRID BCL2L12 GeneID BioGRID Negative Genetic
    BOK BioGRID BCL2L13 GeneID BioGRID Negative Genetic
    BOK BioGRID BCL2L11 GeneID BioGRID Negative Genetic
    BOK BioGRID HRK GeneID BioGRID Negative Genetic
    BOK BioGRID BNIP3L GeneID BioGRID Negative Genetic
    BOK BioGRID BAK1 GeneID BioGRID Negative Genetic
    BOK BioGRID BAD GeneID BioGRID Negative Genetic
    BOK BioGRID M GeneID BioGRID Affinity Capture-Western
    BOK BioGRID IRAG1 GeneID BioGRID Affinity Capture-MS
    BOK BioGRID TESPA1 GeneID BioGRID Affinity Capture-MS
    BOK BioGRID BBOX1 GeneID BioGRID Affinity Capture-MS
    BOK BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    BOK BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
    BOK BioGRID MYC GeneID BioGRID Dosage Lethality
    BOK BioGRID NOA1 GeneID BioGRID Two-hybrid
    BOK Protein MCL1 GeneID HPRD None
    BOK Protein BCL2A1 GeneID HPRD None
    BOK BioGRID MCL1 GeneID BioGRID Two-hybrid
    BOK BioGRID BCL2A1 GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    BOK PACSIN3 0 0 0 155 1 1
    BOK SLC35E2 0 0 181 416 1 1
    BOK EXOG 0 0 0 158 1 1
    BOK CASP16 0 0 0 229 1 1
    BOK YAP1 0 0 0 152 1 1
    BOK BCL2L14 0 0 469 469 1 1
    BOK GORAB 0 0 138 244 1 1
    BOK PCDH1 0 0 0 157 1 1
    BOK ADCY8 0 0 0 206 1 1
    BOK B3GALT2 0 0 46 181 1 1
    BOK MCL1 476 0 957 976 1 2
    BOK CHCHD3 0 0 92 154 1 1
    BOK RCHY1 0 0 123 215 1 1
    BOK MAPK10 0 0 0 187 1 2
    BOK BAG1 0 0 213 240 1 2
    BOK NGFR 0 0 96 168 1 1
    BOK E2F3 0 0 108 218 1 1
    BOK EDIL3 0 0 0 170 1 1
    BOK TRAF7 0 0 187 240 1 1
    BOK DNM1L 0 0 149 321 1 2
    BOK CASP5 0 0 167 305 1 1
    BOK SCARA3 0 0 0 157 1 1
    BOK E2F5 0 0 59 221 1 1
    BOK SLC2A14 0 0 0 347 1 1
    BOK BARHL1 0 0 0 254 1 1
    BOK DECR2 0 0 118 271 1 1
    BOK PTEN 0 0 167 270 1 2
    BOK VWA1 0 0 0 151 1 1
    BOK PLXNB3 0 0 0 169 1 1
    BOK RBBP8NL 0 0 0 153 1 1
    BOK FAIM2 0 0 0 205 1 1
    BOK AXIN1 0 0 57 160 1 1
    BOK AIF1L 0 0 124 236 1 1
    BOK ATM 0 0 155 164 1 1
    BOK CASKIN2 0 0 0 153 1 1
    BOK CDKN2A 0 0 138 151 1 2
    BOK CASP4 0 0 193 327 1 2
    BOK PDE1A 0 0 0 227 1 1
    BOK MTCH2 0 0 70 165 1 1
    BOK QSOX2 0 0 63 157 1 1
    BOK CRYAB 0 0 86 164 1 1
    BOK CARD16 0 0 0 200 1 1
    BOK PRELID1 0 0 0 291 1 1
    BOK TNFRSF21 0 0 123 155 1 1
    BOK CASP3 0 0 415 512 1 2
    BOK TSPAN9 0 0 0 177 1 1
    BOK BCAR1 0 0 0 213 1 1
    BOK TNFRSF10B 0 0 233 295 1 1
    BOK ASAH1 0 0 155 158 1 1
    BOK SLC27A3 0 0 96 301 1 1
    BOK TMCC3 0 0 53 311 1 1
    BOK TRPC4 0 0 117 225 1 1
    BOK OMA1 0 0 95 151 1 1
    BOK TMBIM1 0 0 82 171 1 1
    BOK BECN1 0 0 249 421 1 2
    BOK TBX22 0 0 81 443 1 1
    BOK SERPINA7 0 0 0 260 1 1
    BOK PEA15 0 0 81 262 1 1
    BOK PMAIP1 0 0 662 698 1 1
    BOK SLC45A2 0 0 54 199 1 1
    BOK BCL2L15 0 0 407 497 1 1
    BOK NHP2 0 0 45 215 1 1
    BOK AMOTL2 0 0 0 188 1 1
    BOK FASLG 0 0 245 244 1 1
    BOK BIRC7 0 0 134 176 1 1
    BOK CASP14 0 0 181 317 1 1
    BOK HSPA5 0 0 138 168 1 2
    BOK DNM1 0 0 0 254 1 1
    BOK BTRC 0 0 60 198 1 1
    BOK ASAH2 0 0 112 173 1 1
    BOK EPAS1 0 0 90 168 1 2
    BOK NOP10 0 0 0 214 1 1
    BOK BBC3 0 0 503 503 1 1
    BOK GLYATL3 0 0 257 256 1 1
    BOK ILF2 0 0 125 158 1 1
    BOK TRIM2 0 0 153 632 1 1
    BOK BIRC8 0 0 150 184 1 1
    BOK PINK1 0 0 61 328 1 2
    BOK CLGN 0 0 0 163 1 1
    BOK CCNG2 0 0 66 216 1 1
    BOK XIAP 0 0 216 247 1 1
    BOK AQPEP 0 0 0 189 1 1
    BOK E2F4 0 0 70 230 1 1
    BOK S100A16 0 0 0 152 1 1
    BOK HAS3 0 0 109 293 1 1
    BOK HUS1 0 0 52 155 1 1
    BOK CPNE6 0 0 125 186 1 1
    BOK CARD8 0 0 0 200 1 1
    BOK FAS 0 0 194 194 1 2
    BOK UCN 0 0 0 157 1 1
    BOK AKT1 0 0 206 225 1 2
    BOK FBN3 0 0 96 210 1 1
    BOK MYBPC1 0 0 95 199 1 1
    BOK VDAC1 0 0 150 164 1 2
    BOK MRPL16 0 0 0 208 1 1
    BOK BNIP3L 0 0 278 289 1 2
    BOK OXR1 0 0 0 179 1 1
    BOK SEMA3F 0 0 0 151 1 1
    BOK NRG1 0 0 0 189 1 2
    BOK SLC35E2B 0 0 157 399 1 1
    BOK PDE1B 0 0 86 435 1 1
    BOK EIF2AK3 0 0 151 158 1 2
    BOK FBXW11 0 0 0 182 1 1
    BOK BIRC6 0 0 113 211 1 1
    BOK BNIP1 0 0 194 199 1 2
    BOK NOP58 0 0 0 190 1 1
    BOK HSPA12A 0 0 107 464 1 1
    BOK FOXO3 0 0 161 189 1 2
    BOK RABEP2 0 0 49 308 1 1
    BOK MCU 0 0 181 186 1 1
    BOK CRIP2 0 0 96 248 1 1
    BOK FAM129B 0 0 0 151 1 1
    BOK PROZ 0 0 123 472 1 1
    BOK RNF170 0 0 125 313 1 1
    BOK DPYD 0 0 47 193 1 1
    BOK TNFRSF10D 0 0 100 156 1 1
    BOK CCND1 0 0 107 185 1 1
    BOK BCL2L2 0 0 690 308 1 1
    BOK GRAMD4 0 0 166 165 1 1
    BOK FAU 0 0 0 163 1 1
    BOK IFT43 0 0 167 167 1 1
    BOK BAD 0 0 467 584 1 1
    BOK SLC27A4 0 0 0 184 1 1
    BOK SLC9B1 0 0 0 258 1 1
    BOK MAP4K3 0 0 0 150 1 1
    BOK HRK 0 0 654 654 1 1
    BOK CANX 0 0 67 186 1 2
    BOK AVEN 0 0 171 228 1 1
    BOK PHLPP2 0 0 0 207 1 1
    BOK BAK1 0 0 556 565 1 2
    BOK BCL2 0 0 273 273 1 2
    BOK MICU2 0 0 123 176 1 1
    BOK PAXBP1 0 0 167 167 1 1
    BOK CARD18 0 0 0 200 1 1
    BOK DFFA 0 0 210 243 1 1
    BOK MAP4K2 0 0 73 193 1 1
    BOK NOL10 0 0 0 163 1 1
    BOK GPC1 0 0 0 213 1 1
    BOK FIS1 0 0 150 168 1 2
    BOK NAIP 0 0 127 170 1 1
    BOK CASP2 0 0 217 512 1 1
    BOK AEN 0 0 112 281 1 1
    BOK DKK3 0 0 0 155 1 1
    BOK GFER 0 0 82 232 1 1
    BOK KIAA0141 0 0 243 321 1 1
    BOK UBAC2 0 0 134 165 1 1
    BOK C22orf29 0 0 528 528 1 1
    BOK TNF 0 0 135 151 1 1
    BOK EPB41L1 0 0 0 182 1 1
    BOK OR1Q1 0 0 247 690 1 1
    BOK SGOL2 0 0 96 189 1 1
    BOK EPHB4 0 0 57 223 1 1
    BOK GADD45A 0 0 156 156 1 1
    BOK BCL2A1 192 0 595 658 1 1
    BOK SNCG 0 0 0 151 1 1
    BOK BMF 0 0 422 575 1 1
    BOK BCAP31 0 0 193 208 1 1
    BOK ENSG00000196136 0 0 0 160 1 1
    BOK ERAP2 0 0 0 188 1 1
    BOK COL26A1 0 0 0 154 1 1
    BOK SERPINA10 0 0 107 466 1 1
    BOK GNG13 0 0 139 348 1 1
    BOK ABLIM3 0 0 0 159 1 1
    BOK HSF5 0 0 67 210 1 1
    BOK MAPK8 0 0 134 212 1 2
    BOK PDE1C 0 0 0 230 1 1
    BOK PKDCC 0 0 122 285 1 1
    BOK GPX4 0 0 90 185 1 1
    BOK DIABLO 0 0 390 431 1 1
    BOK GRINA 0 0 0 249 1 1
    BOK MX2 0 0 0 235 1 1
    BOK MPPED1 0 0 167 333 1 1
    BOK PSMD4 0 0 0 157 1 1
    BOK RPAP2 0 0 112 668 1 1
    BOK SLC8A3 0 0 81 223 1 1
    BOK AIFM2 0 0 96 176 1 1
    BOK ITIH5 0 0 134 152 1 1
    BOK ITPR1 0 0 438 438 1 2
    BOK CASP9 0 0 391 531 1 1
    BOK GULP1 0 0 74 150 1 1
    BOK CTXN1 0 0 0 151 1 1
    BOK CYCS 0 0 518 563 1 1
    BOK SRP72 0 0 180 179 1 1
    BOK SLC30A1 0 0 66 154 1 1
    BOK RNF183 0 0 146 232 1 1
    BOK BIRC3 0 0 195 234 1 1
    BOK TNFRSF10A 0 0 232 280 1 1
    BOK CPNE9 0 0 173 257 1 1
    BOK CARD17 0 0 0 200 1 1
    BOK CASP8 0 0 391 492 1 2
    BOK MTSS1L 0 0 0 152 1 1
    BOK SPINT3 0 0 270 270 1 1
    BOK CASP7 0 0 260 613 1 1
    BOK ABCF2 0 0 0 191 1 1
    BOK TTC5 0 0 155 156 1 1
    BOK MAP1LC3C 0 0 69 323 1 2
    BOK DNM2 45 0 42 239 1 1
    BOK TRADD 0 0 160 170 1 1
    BOK MAPKAPK2 0 0 0 190 1 1
    BOK KCNIP3 0 0 0 152 1 1
    BOK BCL2L13 0 0 460 475 1 1
    BOK BCL2L10 0 0 654 654 1 1
    BOK BID 0 0 457 610 1 1
    BOK CDKN1A 0 0 166 165 1 2
    BOK BCLAF1 0 0 134 161 1 1
    BOK BAX 0 0 510 203 1 2
    BOK UMPS 0 0 96 484 1 1
    BOK BCL2L12 0 0 213 612 1 1
    BOK SLC9A6 0 0 74 247 1 1
    BOK SMDT1 0 0 150 203 1 1
    BOK OCA2 0 0 49 195 1 1
    BOK NOP56 0 0 0 212 1 1
    BOK MAP4K5 0 0 0 150 1 1
    BOK NHP2L1 0 0 0 214 1 1
    BOK PSEN1 0 0 0 202 1 2
    BOK HTRA2 0 0 246 363 1 1
    BOK AATK 0 0 170 249 1 1
    BOK ACSS3 0 0 124 212 1 1
    BOK MED25 0 0 157 156 1 1
    BOK ACTB 0 0 171 183 1 1
    BOK BNIP3 0 0 183 253 1 2
    BOK CHEK1 0 0 95 157 1 1
    BOK GAS2L1 0 0 0 150 1 1
    BOK BAG5 0 0 193 281 1 1
    BOK CASP1 0 0 157 297 1 2
    BOK TNFSF10 0 0 151 150 1 2
    BOK APPBP2 0 0 123 349 1 1
    BOK SLC9A7 0 0 81 173 1 1
    BOK SLC45A1 0 0 0 172 1 1
    BOK UBA6 0 0 57 206 1 1
    BOK TMTC4 0 0 86 388 1 1
    BOK BCL2L11 0 0 744 775 1 1
    BOK AMFR 0 0 489 489 1 1
    BOK JUN 0 0 163 163 1 1
    BOK ITPR3 0 0 249 267 1 1
    BOK COL16A1 0 0 0 151 1 1
    BOK FBL 0 0 0 152 1 1
    BOK NDUFAF4 0 0 107 162 1 1
    BOK OR1B1 0 0 314 451 1 1
    BOK MFN1 0 0 164 390 1 1
    BOK BIK 0 0 690 692 1 1
    BOK SEPT4 0 0 90 180 1 1
    BOK TRIM3 0 0 84 465 1 1
    BOK BARHL2 0 0 0 254 1 1
    BOK SLC35C2 0 0 0 158 1 1
    BOK ANXA5 0 0 212 212 1 1
    BOK TMTC3 0 0 0 188 1 1
    BOK NPEPPS 0 0 0 205 1 1
    BOK HSPD1 81 0 0 195 1 1
    BOK NBL1 0 0 0 154 1 1
    BOK NCS1 0 0 0 165 1 1
    BOK SLC5A5 0 0 55 223 1 1
    BOK BIRC2 0 0 260 296 1 1
    BOK SLC25A10 0 0 0 188 1 1
    BOK USP9X 0 0 142 165 1 1
    BOK SDF4 0 0 45 182 1 1
    BOK CDK10 0 0 81 156 1 1
    BOK BCL9L 0 0 74 183 1 1
    BOK GAPDH 0 0 150 166 1 2
    BOK KITLG 0 0 66 191 1 1
    BOK ZNF251 0 0 82 186 1 1
    BOK JADE2 0 0 113 248 1 1
    BOK CASP6 0 0 260 382 1 1
    BOK PHLPP1 0 0 0 207 1 1
    BOK TSNARE1 0 0 167 695 1 1
    BOK BCL2L1 0 0 612 263 1 2
    BOK SLC35G1 0 0 140 374 1 1
    BOK MFN2 0 0 161 388 1 2
    BOK TRIM13 0 0 61 285 1 2
    BOK AMIGO2 0 0 160 235 1 1
    BOK DNM3 0 0 0 235 1 1
    BOK ERAP1 0 0 0 205 1 1
    BOK BAG3 0 0 162 206 1 2
    BOK TRAF5 0 0 180 179 1 1
    BOK UNC79 0 0 44 464 1 1
    BOK PIK3C3 0 0 74 174 1 2
    BOK ZIK1 0 0 66 172 1 1
    BOK BCL2L2-PABPN1 0 0 662 267 1 1
    BOK ENDOG 0 0 236 407 1 1
    BOK TNFRSF1A 0 0 134 159 1 1
    BOK PIDD1 0 0 140 153 1 1
    BOK TRAF4 0 0 150 212 1 1
    BOK PSEN2 0 0 43 363 1 1
    BOK FIGNL1 0 0 137 220 1 1
    BOK CEP170B 0 0 0 214 1 1
    BOK TRIM59 0 0 102 179 1 1
    BOK E2F2 0 0 52 169 1 1
    BOK LIPH 0 0 113 203 1 1
    BOK TESPA1 493 0 0 493 1 1
    BOK SLC9A3R2 0 0 0 197 1 1
    BOK TRAF1 0 0 138 157 1 1
    BOK FAM96A 0 0 160 159 1 1
    BOK CRADD 0 0 250 304 1 1
    BOK LAMB2 0 0 0 151 1 1
    BOK SLC25A4 0 0 106 189 1 1
    BOK TP53 0 0 346 377 1 2
    BOK MDM2 0 0 193 205 1 1
    BOK BNIP2 0 0 143 162 1 1
    BOK FADD 0 0 248 324 1 2
    BOK EGFR 0 0 123 213 1 1
    BOK CFLAR 0 0 260 431 1 1
    BOK ERN1 0 0 151 165 1 2
    BOK SLC9B2 0 0 122 509 1 1
    BOK ABCA3 0 0 57 191 1 1
    BOK TBCD 0 0 95 205 1 1
    BOK HTRA1 0 0 0 284 1 1
    BOK VDAC2 0 0 261 295 1 1
    BOK HSPA12B 0 0 0 278 1 1
    BOK APAF1 0 0 458 767 1 1
    BOK KIF18B 0 0 108 173 1 1
    BOK HUWE1 0 0 165 178 1 1
    BOK PIN1 0 0 143 156 1 1
    BOK THAP4 0 0 384 384 1 1
    BOK ADCY1 0 0 72 170 1 1
    BOK MX1 0 0 57 248 1 1
    BOK TMBIM6 0 0 45 160 1 1
    BOK NOG 0 0 0 197 1 1
    BOK SCN2A 0 0 0 195 1 1
    BOK DVL1 0 0 47 244 1 1
    BOK CASP8AP2 0 0 147 200 1 1
    BOK MICU1 0 0 112 327 1 1
    BOK MYC 116 0 212 285 1 2
    BOK PARK2 0 0 45 381 1 1
    BOK MS4A3 0 0 123 401 1 1
    BOK NCOA7 0 0 0 179 1 1
    BOK SLC30A10 0 0 53 241 1 1
    BOK DAB2IP 0 0 0 183 1 2
    BOK GNG12 0 0 0 191 1 1
    BOK PHLDA3 0 0 85 187 1 1
    BOK SLC29A2 0 0 67 297 1 1
    BOK MFF 0 0 124 204 1 1
    BOK OPA1 0 0 0 240 1 1
    BOK CDKN2D 0 0 150 194 1 1
    BOK RTDR1 0 0 208 208 1 1
    BOK SLC2A3 0 0 45 350 1 1
    BOK NOL3 0 0 155 188 1 1
    BOK UBA1 0 0 55 204 1 1
    BOK HSD17B10 0 0 69 365 1 1
    BOK CASP10 0 0 160 299 1 1
    BOK MOAP1 0 0 170 169 1 1
    BOK BLID 0 0 185 185 1 1
    BOK PARK7 0 0 0 395 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0051400 Molecular Function BH domain binding enables IEA
    GO:0015267 Molecular Function channel activity enables IBA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0046982 Molecular Function protein heterodimerization activity enables ISS
    GO:0042803 Molecular Function protein homodimerization activity enables ISS
    GO:0044877 Molecular Function protein-containing complex binding enables IEA
    GO:0005102 Molecular Function signaling receptor binding enables IEA
    GO:0031625 Molecular Function ubiquitin protein ligase binding enables IEA
    GO:0006915 Biological Process apoptotic process involved_in IDA
    GO:0006921 Biological Process cellular component disassembly involved in execution phase of apoptosis involved_in ISS
    GO:0097192 Biological Process extrinsic apoptotic signaling pathway in absence of ligand involved_in IBA
    GO:0072332 Biological Process intrinsic apoptotic signaling pathway by p53 class mediator involved_in IMP
    GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IBA
    GO:0008584 Biological Process male gonad development involved_in IEA
    GO:0051902 Biological Process negative regulation of mitochondrial depolarization involved_in IEA
    GO:1901029 Biological Process negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway involved_in IEA
    GO:0060546 Biological Process negative regulation of necroptotic process involved_in IEA
    GO:0043524 Biological Process negative regulation of neuron apoptotic process involved_in IEA
    GO:0051402 Biological Process neuron apoptotic process involved_in IEA
    GO:0048709 Biological Process oligodendrocyte differentiation involved_in IEA
    GO:1903899 Biological Process positive regulation of PERK-mediated unfolded protein response involved_in ISS
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IBA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
    GO:1902237 Biological Process positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway involved_in ISS
    GO:1900119 Biological Process positive regulation of execution phase of apoptosis involved_in IMP
    GO:2001244 Biological Process positive regulation of intrinsic apoptotic signaling pathway involved_in ISS
    GO:1901030 Biological Process positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway involved_in ISS
    GO:0051259 Biological Process protein complex oligomerization involved_in ISS
    GO:0010506 Biological Process regulation of autophagy involved_in IMP
    GO:1901382 Biological Process regulation of chorionic trophoblast cell proliferation involved_in IDA
    GO:0051480 Biological Process regulation of cytosolic calcium ion concentration involved_in IEA
    GO:1904708 Biological Process regulation of granulosa cell apoptotic process involved_in IMP
    GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IBA
    GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IDA
    GO:0072718 Biological Process response to cisplatin involved_in IEA
    GO:0055085 Biological Process transmembrane transport involved_in IEA
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0033106 Cellular Component cis-Golgi network membrane located_in ISS
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0031901 Cellular Component early endosome membrane located_in ISS
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IDA
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0005743 Cellular Component mitochondrial inner membrane located_in IDA
    GO:0031966 Cellular Component mitochondrial membrane located_in IDA
    GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IBA
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0005640 Cellular Component nuclear outer membrane located_in IEA
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0055038 Cellular Component recycling endosome membrane located_in ISS
    GO:0032588 Cellular Component trans-Golgi network membrane located_in ISS
    Pathways
    Name DB ID
    2q37 copy number variation syndrome (WP5224) WikiPathways WP5224_r122740
    Regulation of apoptosis by parathyroid hormone-related protein (WP3872) WikiPathways WP3872_r123397
    TP53 network (WP1742) WikiPathways WP1742_r116592
    Apoptosis (WP254) WikiPathways WP254_r118382
    Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_047445588 1 mRNA transcript variant X3 NC_000002 Reference
    XM_011511696 3 mRNA transcript variant X1 NC_000002 Reference
    NM_032515 5 mRNA None NC_000002 Reference
    XM_011511697 4 mRNA transcript variant X4 NC_000002 Reference
    XM_047445590 1 mRNA transcript variant X6 NC_000002 Reference
    XM_047445589 1 mRNA transcript variant X5 NC_000002 Reference
    XM_047445587 1 mRNA transcript variant X2 NC_000002 Reference