BNIP3L

BCL2 interacting protein 3 like
General Information
Name BCL2 interacting protein 3 like
Alias
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A
  • BCL2/adenovirus E1B 19-kd protein-interacting protein 3a
  • BCL2/adenovirus E1B 19kDa interacting protein 3 like
  • NIP-3-like protein X
  • NIP3-like protein X
  • NIP3L
  • adenovirus E1B19k-binding protein B5
Synonyms Nix BNIP3a NIX
Gene_family None
organism Homo sapiens
entrez_id 665
location 8p21.2
transcript_count 2
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]
      Stringdb BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEA [...]
      nextProt Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    BNIP3L BioGRID FBXL4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
    BNIP3L BioGRID VANGL2 GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID TMEM132D GeneID BioGRID Two-hybrid
    BNIP3L BioGRID BOK GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BNIP3 GeneID BioGRID Affinity Capture-MS; Negative Genetic; Two-hybrid
    BNIP3L BioGRID BIK GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BAX GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BAK1 GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BAD GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BMF GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BCL2L12 GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BCL2L13 GeneID BioGRID Negative Genetic
    BNIP3L BioGRID BCL2L11 GeneID BioGRID Negative Genetic
    BNIP3L BioGRID HRK GeneID BioGRID Negative Genetic
    BNIP3L BioGRID PMAIP1 GeneID BioGRID Negative Genetic
    BNIP3L BioGRID CBL GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID ORF10 GeneID BioGRID Affinity Capture-Western; Co-localization
    BNIP3L BioGRID WIPI2 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID RNF149 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID SPSB4 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID AKAP1 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID ATP5MK GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID MYO19 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID SPATA7 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID HTRA2 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID SLC25A46 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID RHOT2 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID OCIAD1 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID MTCH2 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID MTCH1 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID CIT GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID MTX2 GeneID BioGRID Proximity Label-MS
    BNIP3L BioGRID KIF23 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID HTR2B GeneID BioGRID Two-hybrid
    BNIP3L BioGRID MAP1LC3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BNIP3L BioGRID BAG3 GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID TMEM120B GeneID BioGRID Two-hybrid
    BNIP3L BioGRID CYB5B GeneID BioGRID Two-hybrid
    BNIP3L BioGRID CLEC7A GeneID BioGRID Two-hybrid
    BNIP3L BioGRID TNMD GeneID BioGRID Two-hybrid
    BNIP3L BioGRID SMCO4 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID TMPRSS4 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID GABARAPL1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BNIP3L BioGRID GABARAPL2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BNIP3L BioGRID TMEM11 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID MALL GeneID BioGRID Two-hybrid
    BNIP3L BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID NGFR GeneID BioGRID Affinity Capture-Western; PCA; Reconstituted Complex
    BNIP3L BioGRID ADIPOQ GeneID BioGRID Two-hybrid
    BNIP3L BioGRID BNIP3L GeneID BioGRID Two-hybrid
    BNIP3L BioGRID ATG8 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID LMNA GeneID BioGRID Two-hybrid
    BNIP3L BioGRID PPTC7 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID BCL2L1 GeneID BioGRID Reconstituted Complex
    BNIP3L BioGRID BCL2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BNIP3L BioGRID LDLRAD1 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID FATE1 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID MAP1LC3B GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID CAMK1D GeneID BioGRID Two-hybrid
    BNIP3L BioGRID CEP192 GeneID BioGRID Affinity Capture-MS
    BNIP3L BioGRID GABARAP GeneID BioGRID Affinity Capture-Western
    BNIP3L BioGRID CASK GeneID BioGRID Two-hybrid
    BNIP3L BioGRID ECM1 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID DUSP3 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID CLN8 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID RHEB GeneID BioGRID Two-hybrid
    BNIP3L BioGRID ATP13A2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BNIP3L BioGRID GNB5 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID ROBO2 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID GBP2 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID KLHL23 GeneID BioGRID Two-hybrid
    BNIP3L Protein DOK5 GeneID HPRD None
    BNIP3L Protein RINT1 GeneID HPRD None
    BNIP3L Protein TMEM11 GeneID HPRD None
    BNIP3L Protein STEAP3 GeneID HPRD None
    BNIP3L Protein BNIP3L GeneID HPRD None
    BNIP3L Protein BNIP3 GeneID HPRD None
    BNIP3L Protein BCL2L1 GeneID HPRD None
    BNIP3L Protein BCL2 GeneID HPRD None
    BNIP3L Protein EWSR1 GeneID HPRD None
    BNIP3L BioGRID STEAP3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BNIP3L BioGRID DOK5 GeneID BioGRID Two-hybrid
    BNIP3L BioGRID EWSR1 GeneID BioGRID Two-hybrid
    BNIP3L Nucleotide TP53 GeneID BIND p53 interacts with Bnip3L.
    BNIP3L Nucleotide CREBBP GeneID BIND CBP interacts with Bnip3L.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    BNIP3L WDR45 0 0 167 197 1 2
    BNIP3L RB1CC1 0 0 556 596 1 2
    BNIP3L RNF41 0 0 142 161 1 1
    BNIP3L NFE2L2 0 0 248 248 1 1
    BNIP3L PGAM5 0 0 465 514 1 1
    BNIP3L UVRAG 0 0 467 478 1 2
    BNIP3L WDFY3 0 0 391 394 1 2
    BNIP3L SERINC1 0 0 66 326 1 1
    BNIP3L TNMD 273 0 0 273 1 1
    BNIP3L IGF1 0 0 207 207 1 1
    BNIP3L ATF3 0 0 195 195 1 1
    BNIP3L STK11 0 0 261 266 1 2
    BNIP3L PGAM1 0 0 134 171 1 1
    BNIP3L PDGFB 0 0 96 234 1 1
    BNIP3L BRCA1 0 0 166 165 1 1
    BNIP3L PPIF 0 0 323 332 1 1
    BNIP3L OPA1 0 0 310 320 1 1
    BNIP3L GADD45A 0 0 278 287 1 1
    BNIP3L PKM 0 0 235 235 1 1
    BNIP3L CCPG1 0 0 268 287 1 1
    BNIP3L MFF 0 0 455 466 1 1
    BNIP3L PFKFB4 0 0 232 244 1 1
    BNIP3L BMF 0 0 294 304 1 1
    BNIP3L SLC2A3 0 0 194 194 1 1
    BNIP3L TXNIP 0 0 150 212 1 1
    BNIP3L NOL3 0 0 146 208 1 1
    BNIP3L BCL2A1 0 0 295 311 1 1
    BNIP3L DRAM1 0 0 369 369 1 2
    BNIP3L TMEM45A 0 0 283 338 1 1
    BNIP3L LRP1B 0 0 97 159 1 1
    BNIP3L CIDEB 0 0 208 268 1 1
    BNIP3L EIF5B 0 0 323 323 1 1
    BNIP3L RAB7A 0 0 358 419 1 2
    BNIP3L TRAK2 0 0 113 157 1 1
    BNIP3L CASP10 0 0 144 418 1 1
    BNIP3L ATG4B 0 0 468 488 1 2
    BNIP3L FAM117B 0 0 103 178 1 1
    BNIP3L PPTC7 275 0 103 361 1 1
    BNIP3L PARK7 0 0 286 291 1 1
    BNIP3L TFRC 0 0 202 202 1 1
    BNIP3L MOAP1 0 0 139 373 1 1
    BNIP3L NELFCD 0 0 0 207 1 1
    BNIP3L LDLRAD1 334 0 0 334 1 1
    BNIP3L TAX1BP1 0 0 470 507 1 2
    BNIP3L TRAF2 0 0 108 161 1 1
    BNIP3L ZFAND5 0 0 113 288 1 1
    BNIP3L RICTOR 0 0 136 164 1 2
    BNIP3L EGLN3 0 0 294 336 1 1
    BNIP3L PPP1R3C 0 0 84 339 1 1
    BNIP3L PHYHIP 0 0 170 169 1 1
    BNIP3L UBL5 0 0 150 169 1 1
    BNIP3L CASP8AP2 0 0 70 423 1 1
    BNIP3L DVL1 0 0 0 161 1 1
    BNIP3L ZBTB22 0 0 60 155 1 1
    BNIP3L DCTN4 0 0 69 161 1 1
    BNIP3L MSRA 0 0 53 159 1 1
    BNIP3L USP15 0 0 150 191 1 1
    BNIP3L WIPI2 412 0 376 628 1 2
    BNIP3L PPAP2B 0 0 0 187 1 1
    BNIP3L WDR45B 0 0 149 226 1 1
    BNIP3L ATP13A2 270 0 108 321 1 2
    BNIP3L NAIP 0 0 194 194 1 1
    BNIP3L BAG4 0 0 218 235 1 1
    BNIP3L FIS1 0 0 561 588 1 2
    BNIP3L EFNA4 0 0 46 151 1 1
    BNIP3L PDK1 0 0 330 336 1 1
    BNIP3L IRGM 0 0 193 219 1 2
    BNIP3L MYC 0 0 260 260 1 2
    BNIP3L PPRC1 0 0 60 223 1 1
    BNIP3L CASP2 0 0 123 233 1 1
    BNIP3L KDM3A 0 0 74 171 1 1
    BNIP3L POLR2G 0 0 52 192 1 1
    BNIP3L IL18 0 0 143 169 1 1
    BNIP3L STEAP3 270 800 771 963 1 1
    BNIP3L TMSNB 0 0 207 225 1 1
    BNIP3L PARK2 0 0 654 675 1 1
    BNIP3L APC2 0 0 156 155 1 1
    BNIP3L NT5E 0 0 62 156 1 1
    BNIP3L C22orf29 0 0 521 521 1 1
    BNIP3L LINS 0 0 67 187 1 1
    BNIP3L BLOC1S1 0 0 159 158 1 1
    BNIP3L H1F0 0 0 0 189 1 1
    BNIP3L NBR1 0 0 722 750 1 2
    BNIP3L PPARGC1A 0 0 486 508 1 1
    BNIP3L TNF 0 0 213 213 1 1
    BNIP3L TECPR2 0 0 150 173 1 2
    BNIP3L AATF 0 0 122 216 1 1
    BNIP3L EDN2 0 0 136 171 1 1
    BNIP3L ERN1 0 0 182 181 1 2
    BNIP3L CDIP1 0 0 0 189 1 1
    BNIP3L CAT 0 0 294 337 1 1
    BNIP3L LRP6 0 0 0 188 1 1
    BNIP3L TIMM23B 0 0 163 163 1 1
    BNIP3L CD300C 0 0 841 841 1 1
    BNIP3L VDAC2 0 0 157 197 1 1
    BNIP3L ATG2A 0 0 210 219 1 2
    BNIP3L CANX 0 0 97 153 1 2
    BNIP3L TXN 0 0 149 168 1 1
    BNIP3L KCNH7 0 0 58 196 1 1
    BNIP3L RAB9A 0 0 91 332 1 2
    BNIP3L FH 0 0 173 185 1 1
    BNIP3L HRK 0 0 310 368 1 1
    BNIP3L STAT3 0 0 181 181 1 2
    BNIP3L JAK2 0 0 90 182 1 1
    BNIP3L BCL2 486 0 217 594 1 2
    BNIP3L BAK1 0 0 261 304 1 2
    BNIP3L MTCH1 117 0 113 184 1 1
    BNIP3L GPAM 0 0 67 206 1 1
    BNIP3L MDN1 0 0 55 313 1 1
    BNIP3L KIF23 270 0 0 270 1 1
    BNIP3L SNX22 0 0 95 190 1 1
    BNIP3L RHEB 192 0 983 986 1 2
    BNIP3L HDAC6 0 0 283 282 1 2
    BNIP3L APAF1 0 0 321 342 1 1
    BNIP3L UXS1 0 0 95 260 1 1
    BNIP3L DDIT4 0 0 395 394 1 1
    BNIP3L TBC1D17 0 0 193 210 1 1
    BNIP3L TECPR1 0 0 179 179 1 2
    BNIP3L CARD18 0 0 0 161 1 1
    BNIP3L DFFA 0 0 125 213 1 1
    BNIP3L CISD2 0 0 285 284 1 2
    BNIP3L NR4A1 270 0 453 583 1 1
    BNIP3L LMNA 274 0 74 322 1 1
    BNIP3L EXO1 0 0 0 207 1 1
    BNIP3L ANKRD37 0 0 193 222 1 1
    BNIP3L TRIM65 0 0 81 381 1 1
    BNIP3L PLOD1 0 0 158 183 1 1
    BNIP3L PPP1R3B 0 0 0 155 1 1
    BNIP3L CCND1 0 0 181 181 1 1
    BNIP3L HK2 0 0 170 169 1 1
    BNIP3L ALDOC 0 0 259 291 1 1
    BNIP3L SIAH2 0 0 139 155 1 1
    BNIP3L TIMM23 0 0 217 217 1 1
    BNIP3L ARHGEF7 0 0 0 300 1 1
    BNIP3L BCL2L2 0 0 365 374 1 1
    BNIP3L DDIT3 0 0 194 194 1 2
    BNIP3L HDAC2 0 0 112 152 1 1
    BNIP3L CRADD 0 0 186 262 1 1
    BNIP3L TNNT3 0 0 54 251 1 1
    BNIP3L CYB561D1 0 0 136 372 1 1
    BNIP3L MAP1A 0 0 496 531 1 1
    BNIP3L EGR2 0 0 123 177 1 1
    BNIP3L STEAP4 0 0 447 447 1 1
    BNIP3L PRPSAP1 0 0 103 159 1 1
    BNIP3L LOX 0 0 161 161 1 1
    BNIP3L CREBL2 0 0 107 213 1 1
    BNIP3L CBL 0 0 74 175 1 1
    BNIP3L MDM2 0 0 194 194 1 1
    BNIP3L TP53 0 900 458 943 1 2
    BNIP3L BNIP2 192 0 294 478 1 1
    BNIP3L DDX54 0 0 74 382 1 1
    BNIP3L SLC6A15 0 0 57 227 1 1
    BNIP3L SESN1 0 0 139 170 1 2
    BNIP3L ZBTB32 0 0 129 366 1 1
    BNIP3L SLC2A1 0 0 391 390 1 1
    BNIP3L LAMP1 0 0 246 273 1 2
    BNIP3L FADD 0 0 243 242 1 2
    BNIP3L STBD1 0 0 298 298 1 2
    BNIP3L ATPIF1 0 0 128 262 1 1
    BNIP3L HTT 0 0 293 319 1 1
    BNIP3L TP53INP2 0 0 213 213 1 2
    BNIP3L RPS6KB1 0 0 248 279 1 2
    BNIP3L BAD 270 0 108 371 1 1
    BNIP3L EGFR 0 0 181 181 1 1
    BNIP3L CFLAR 0 0 235 377 1 1
    BNIP3L TP53INP1 0 0 212 229 1 2
    BNIP3L PIK3C3 0 0 594 607 1 2
    BNIP3L RTN3 0 0 234 234 1 1
    BNIP3L PAPD5 0 0 62 224 1 1
    BNIP3L UCP2 0 0 194 211 1 1
    BNIP3L FAM162A 0 0 126 168 1 1
    BNIP3L IL6 0 0 166 165 1 1
    BNIP3L IGFBP7 0 0 150 245 1 1
    BNIP3L KBTBD7 0 0 151 150 1 1
    BNIP3L EIF2AK3 0 0 243 242 1 2
    BNIP3L FLT1 0 0 154 153 1 1
    BNIP3L BCL2L2-PABPN1 0 0 335 345 1 1
    BNIP3L ENDOG 0 0 246 279 1 1
    BNIP3L TASP1 0 0 60 168 1 1
    BNIP3L VHL 0 0 270 298 1 1
    BNIP3L ATG3 0 0 525 554 1 2
    BNIP3L LGALS3 0 0 88 176 1 1
    BNIP3L ZFAND6 0 0 0 163 1 1
    BNIP3L SH3RF3 0 0 0 347 1 1
    BNIP3L TNFRSF1A 0 0 169 188 1 1
    BNIP3L SUOX 0 0 64 200 1 1
    BNIP3L ANKRD17 0 0 66 224 1 1
    BNIP3L BNIP1 0 0 270 300 1 2
    BNIP3L TRIM28 0 0 134 199 1 2
    BNIP3L BIRC6 0 0 165 180 1 1
    BNIP3L CYR61 0 0 113 165 1 1
    BNIP3L ATG4C 0 0 283 310 1 2
    BNIP3L PEX2 0 0 155 154 1 1
    BNIP3L PKMYT1 0 0 819 819 1 1
    BNIP3L SIAH3 0 0 155 239 1 1
    BNIP3L SRC 0 0 202 251 1 1
    BNIP3L HILPDA 0 0 232 231 1 1
    BNIP3L FOXO3 0 0 509 520 1 2
    BNIP3L TRIM59 0 0 74 162 1 1
    BNIP3L MTOR 0 0 451 455 1 2
    BNIP3L PLSCR3 0 0 217 217 1 1
    BNIP3L XRCC6BP1 0 0 161 166 1 1
    BNIP3L MCU 0 0 170 169 1 1
    BNIP3L SHISA5 0 0 108 172 1 1
    BNIP3L CDKN1B 0 0 142 174 1 2
    BNIP3L CDH20 0 0 0 167 1 1
    BNIP3L HRAS 0 0 161 188 1 1
    BNIP3L MAP1LC3A 486 0 686 847 1 2
    BNIP3L CTNNB1 0 0 126 153 1 1
    BNIP3L OPTC 0 0 67 167 1 1
    BNIP3L ZFYVE1 0 0 380 380 1 2
    BNIP3L RIPK3 0 0 159 158 1 1
    BNIP3L YPEL2 0 0 96 174 1 1
    BNIP3L APP 0 0 163 163 1 1
    BNIP3L MFN2 0 0 564 584 1 2
    BNIP3L TRIM50 0 0 108 174 1 1
    BNIP3L VDAC1 0 0 470 475 1 2
    BNIP3L WIPF3 0 0 82 166 1 1
    BNIP3L TSC2 0 0 287 315 1 2
    BNIP3L LY6K 0 0 72 364 1 1
    BNIP3L RAB7B 0 0 361 421 1 1
    BNIP3L ABCD3 0 0 174 173 1 1
    BNIP3L VAMP7 0 0 90 168 1 1
    BNIP3L ACSL5 0 0 125 160 1 1
    BNIP3L RNFT1 0 0 167 167 1 1
    BNIP3L ATE1 0 0 61 231 1 1
    BNIP3L SIRT5 0 0 257 263 1 1
    BNIP3L YPEL5 0 0 0 186 1 1
    BNIP3L HIF1A 0 0 598 628 1 2
    BNIP3L NDUFA4L2 0 0 160 159 1 1
    BNIP3L EIF2S1 0 0 241 240 1 2
    BNIP3L BAG3 270 0 321 499 1 2
    BNIP3L BEAN1 0 0 113 305 1 1
    BNIP3L IL1B 0 0 181 181 1 1
    BNIP3L ABCC9 0 0 0 240 1 1
    BNIP3L STX17 0 0 218 218 1 2
    BNIP3L TOMM20 0 0 469 481 1 1
    BNIP3L RAB5A 0 0 181 198 1 2
    BNIP3L MARCH5 0 0 414 498 1 1
    BNIP3L NR1H3 0 0 57 190 1 1
    BNIP3L NDRG1 0 0 325 342 1 1
    BNIP3L RNF11 0 0 0 184 1 1
    BNIP3L TBK1 0 0 294 309 1 2
    BNIP3L PRDM2 0 0 0 248 1 1
    BNIP3L TCHP 0 0 163 163 1 1
    BNIP3L ATG2B 0 0 294 302 1 2
    BNIP3L CLN8 192 0 90 246 1 1
    BNIP3L CTSL 0 0 206 223 1 1
    BNIP3L KCNJ8 0 0 0 240 1 1
    BNIP3L HMOX1 0 0 182 203 1 2
    BNIP3L EPB41 0 0 0 264 1 1
    BNIP3L ENO1 0 0 203 234 1 1
    BNIP3L BNIPL 0 0 156 155 1 1
    BNIP3L RUNX2 0 0 0 254 1 1
    BNIP3L PARL 0 0 519 519 1 1
    BNIP3L VMP1 0 0 284 390 1 2
    BNIP3L XIAP 0 0 202 202 1 1
    BNIP3L DUSP5 0 0 96 161 1 1
    BNIP3L GAPDH 0 0 294 294 1 2
    BNIP3L TNFRSF25 0 0 134 170 1 1
    BNIP3L ATG14 0 0 505 531 1 2
    BNIP3L PDDC1 0 0 57 203 1 1
    BNIP3L GABARAPL2 299 800 841 980 1 2
    BNIP3L PGAM4 0 0 150 187 1 1
    BNIP3L TPT1 0 0 739 739 1 1
    BNIP3L FKBP8 0 0 458 469 1 1
    BNIP3L IKBKB 270 0 143 347 1 1
    BNIP3L ATF6 0 0 195 195 1 2
    BNIP3L THRAP3 0 0 48 183 1 1
    BNIP3L CDK8 0 0 0 330 1 1
    BNIP3L CDH6 0 0 139 270 1 1
    BNIP3L BCCIP 0 0 118 271 1 1
    BNIP3L AMZ2 0 0 0 362 1 1
    BNIP3L ABL1 0 0 148 192 1 1
    BNIP3L PIK3R4 0 0 454 470 1 2
    BNIP3L ATF4 0 0 205 205 1 2
    BNIP3L CA9 0 0 325 346 1 1
    BNIP3L ISCU 0 0 167 189 1 1
    BNIP3L WRB 0 0 72 165 1 1
    BNIP3L CASP6 0 0 265 357 1 1
    BNIP3L SH2D1B 0 0 193 193 1 1
    BNIP3L P4HA2 0 0 261 275 1 1
    BNIP3L CARD8 0 0 68 185 1 1
    BNIP3L CLEC7A 300 0 0 300 1 1
    BNIP3L ALDOA 0 0 183 200 1 1
    BNIP3L SEC14L5 0 0 106 188 1 1
    BNIP3L NFKB1 0 0 81 178 1 1
    BNIP3L TOMM7 0 0 159 243 1 1
    BNIP3L PARP11 0 0 60 255 1 1
    BNIP3L PPARG 0 0 202 202 1 1
    BNIP3L PRRC2B 0 0 92 171 1 1
    BNIP3L PTP4A2 0 0 46 158 1 1
    BNIP3L FYCO1 0 0 314 313 1 2
    BNIP3L BCL2L1 462 0 941 968 1 2
    BNIP3L AKT1 0 0 373 373 1 2
    BNIP3L RAB33B 0 0 118 162 1 2
    BNIP3L CPT1A 0 0 54 195 1 1
    BNIP3L PTP4A3 0 0 70 214 1 1
    BNIP3L RELA 0 0 154 172 1 1
    BNIP3L DENR 0 0 260 260 1 1
    BNIP3L BBC3 0 0 235 235 1 1
    BNIP3L MAP1LC3B2 0 0 66 648 1 2
    BNIP3L ANXA5 0 0 247 246 1 1
    BNIP3L FBXO32 0 0 269 269 1 2
    BNIP3L AHSP 0 0 173 191 1 1
    BNIP3L CD34 0 0 95 157 1 1
    BNIP3L NDUFB10 0 0 0 154 1 1
    BNIP3L ZKSCAN3 0 0 155 154 1 2
    BNIP3L SIRT2 0 0 228 234 1 2
    BNIP3L PPP2R2A 0 0 235 278 1 1
    BNIP3L STC2 0 0 212 266 1 1
    BNIP3L RNF187 0 0 88 217 1 1
    BNIP3L PYCARD 0 0 150 244 1 1
    BNIP3L YME1L1 0 0 181 204 1 1
    BNIP3L EPO 0 0 261 261 1 1
    BNIP3L GBAS 0 0 183 205 1 1
    BNIP3L CARD6 0 0 123 155 1 1
    BNIP3L SIAH1 0 0 146 185 1 1
    BNIP3L LONP1 0 0 322 345 1 1
    BNIP3L ESRRA 0 0 218 218 1 1
    BNIP3L PFKFB3 0 0 218 273 1 1
    BNIP3L ARHGEF6 0 0 0 153 1 1
    BNIP3L PHF20 0 0 70 428 1 1
    BNIP3L BTBD2 0 0 96 169 1 1
    BNIP3L EIF4EBP1 0 0 202 239 1 1
    BNIP3L DAZAP2 0 0 73 279 1 1
    BNIP3L ANK3 0 0 45 255 1 1
    BNIP3L CREBBP 0 900 89 905 1 1
    BNIP3L PFKL 0 0 160 186 1 1
    BNIP3L FOXO4 0 0 155 154 1 1
    BNIP3L P4HA1 0 0 341 400 1 1
    BNIP3L ADCY9 0 0 0 303 1 1
    BNIP3L GATM 0 0 77 153 1 1
    BNIP3L LRSAM1 0 0 134 156 1 2
    BNIP3L SIRT4 0 0 244 250 1 1
    BNIP3L ZNF449 0 0 125 205 1 1
    BNIP3L BIRC5 0 0 156 214 1 2
    BNIP3L MCM9 0 0 0 190 1 1
    BNIP3L PINK1 0 0 768 808 1 2
    BNIP3L BIRC2 0 0 193 243 1 1
    BNIP3L CCNG2 0 0 321 370 1 1
    BNIP3L PHC2 0 0 53 416 1 1
    BNIP3L FASLG 0 0 181 181 1 1
    BNIP3L MAT1A 0 0 0 188 1 1
    BNIP3L VCP 0 0 136 168 1 2
    BNIP3L LAMP2 0 0 373 418 1 2
    BNIP3L NCOA4 0 0 171 189 1 1
    BNIP3L ARIH1 0 0 173 173 1 1
    BNIP3L ARNT 0 0 401 414 1 2
    BNIP3L TMEM11 495 0 0 495 1 1
    BNIP3L ANGPTL4 0 0 181 182 1 1
    BNIP3L MEX3B 0 0 57 155 1 1
    BNIP3L ALX1 0 0 0 215 1 1
    BNIP3L AGPAT6 0 0 45 187 1 1
    BNIP3L DEPTOR 0 0 181 181 1 1
    BNIP3L MFN1 0 0 560 566 1 1
    BNIP3L HSPA5 0 0 184 183 1 2
    BNIP3L IGFBP3 0 0 167 167 1 1
    BNIP3L SH3RF2 0 0 74 166 1 1
    BNIP3L DNM1 0 0 166 178 1 1
    BNIP3L ZNF786 0 0 166 165 1 1
    BNIP3L CASP14 0 0 74 190 1 1
    BNIP3L MID2 0 0 90 158 1 1
    BNIP3L IRS2 0 0 48 194 1 1
    BNIP3L MLST8 0 0 184 183 1 2
    BNIP3L BIK 0 0 358 374 1 1
    BNIP3L FUNDC1 0 0 844 867 1 2
    BNIP3L FOXO1 0 0 287 286 1 2
    BNIP3L ANGPT2 0 0 95 151 1 1
    BNIP3L KRAS 0 0 125 197 1 1
    BNIP3L EPAS1 0 0 122 252 1 2
    BNIP3L DUSP3 187 0 0 442 1 1
    BNIP3L TFAM 0 0 370 370 1 1
    BNIP3L SPAG4 0 0 134 194 1 1
    BNIP3L RIPK2 0 0 166 224 1 1
    BNIP3L MAT2A 0 0 0 301 1 1
    BNIP3L RUNX3 0 0 107 170 1 1
    BNIP3L DNAJC13 0 0 66 171 1 1
    BNIP3L SOD2 0 0 234 255 1 1
    BNIP3L SNAP29 0 0 150 252 1 2
    BNIP3L SNCA 0 0 282 297 1 2
    BNIP3L TRIM6 0 0 90 158 1 1
    BNIP3L BECN1 0 0 794 835 1 2
    BNIP3L SLC16A3 0 0 211 211 1 1
    BNIP3L COX4I2 0 0 321 321 1 1
    BNIP3L AKT1S1 0 0 213 226 1 1
    BNIP3L DEDD 0 0 134 157 1 1
    BNIP3L ENSG00000158427 0 0 181 199 1 1
    BNIP3L CASP1 0 0 233 329 1 2
    BNIP3L SLC4A10 0 0 52 222 1 1
    BNIP3L GYS1 0 0 161 161 1 1
    BNIP3L ARID5B 0 0 0 293 1 1
    BNIP3L CAV1 0 0 166 165 1 1
    BNIP3L TNFSF10 0 0 194 208 1 2
    BNIP3L SPATA18 0 0 787 787 1 1
    BNIP3L USMG5 274 0 0 274 1 1
    BNIP3L PMAIP1 0 0 502 502 1 1
    BNIP3L PEA15 0 0 155 261 1 1
    BNIP3L SERINC3 0 0 0 154 1 1
    BNIP3L PEX3 0 0 241 240 1 2
    BNIP3L USP35 0 0 194 195 1 1
    BNIP3L BOK 0 0 278 289 1 2
    BNIP3L TRAF3 0 0 108 241 1 2
    BNIP3L PHB 0 0 181 181 1 1
    BNIP3L ULK2 0 0 469 501 1 2
    BNIP3L TOLLIP 0 0 193 224 1 1
    BNIP3L LRRK2 0 0 218 218 1 2
    BNIP3L BCL2L11 0 0 459 459 1 1
    BNIP3L BCL2L15 0 0 166 165 1 1
    BNIP3L CDH17 0 0 67 167 1 1
    BNIP3L LONP2 0 0 141 171 1 1
    BNIP3L SEC62 0 0 181 212 1 1
    BNIP3L NRF1 0 0 203 203 1 1
    BNIP3L SLC16A4 0 0 211 211 1 1
    BNIP3L AMFR 0 0 171 171 1 1
    BNIP3L PGF 0 0 96 188 1 1
    BNIP3L ITPR3 0 0 161 161 1 1
    BNIP3L LOH12CR1 0 0 0 155 1 1
    BNIP3L JUN 0 0 211 228 1 1
    BNIP3L TEX264 0 0 202 207 1 2
    BNIP3L RHOT1 0 0 260 271 1 1
    BNIP3L DAPK1 0 0 212 217 1 2
    BNIP3L RGCC 0 0 96 189 1 1
    BNIP3L NOD1 0 0 164 182 1 1
    BNIP3L EGLN1 0 0 295 310 1 1
    BNIP3L ATG4D 0 0 241 270 1 2
    BNIP3L PLEKHM1 0 0 325 332 1 2
    BNIP3L NLRP3 0 0 230 229 1 2
    BNIP3L HSP90AA1 0 0 218 218 1 2
    BNIP3L ATG101 0 0 450 462 1 2
    BNIP3L PAX8 0 0 0 189 1 1
    BNIP3L PDIA2 0 0 95 181 1 1
    BNIP3L AGPAT9 0 0 55 195 1 1
    BNIP3L CARD16 0 0 0 161 1 1
    BNIP3L TFEB 0 0 401 402 1 2
    BNIP3L COX4I1 0 0 390 390 1 1
    BNIP3L MUL1 0 0 519 549 1 2
    BNIP3L TP73 0 0 165 184 1 2
    BNIP3L PSEN1 0 0 171 181 1 2
    BNIP3L TNFRSF21 0 0 193 235 1 1
    BNIP3L SETD1A 0 0 0 217 1 1
    BNIP3L HTRA2 274 0 234 421 1 1
    BNIP3L TGFBR3 0 0 46 292 1 1
    BNIP3L SMURF1 0 0 321 321 1 1
    BNIP3L CASP3 0 0 392 468 1 2
    BNIP3L NLRX1 0 0 91 153 1 1
    BNIP3L FTCD 0 0 74 239 1 1
    BNIP3L SPG7 0 0 105 174 1 1
    BNIP3L TNNI2 0 0 0 240 1 1
    BNIP3L CIT 270 0 0 285 1 1
    BNIP3L ATG12 0 0 635 679 1 2
    BNIP3L ACTB 0 0 310 310 1 1
    BNIP3L ATG13 0 0 506 537 1 2
    BNIP3L INS 0 0 233 232 1 1
    BNIP3L TNFRSF10B 0 0 249 248 1 1
    BNIP3L CEP192 270 0 0 270 1 1
    BNIP3L BNIP3 870 0 877 883 1 2
    BNIP3L SQSTM1 270 0 681 763 1 2
    BNIP3L SETD1B 0 0 0 396 1 1
    BNIP3L DIRAS3 0 0 167 180 1 2
    BNIP3L OMA1 0 0 260 260 1 1
    BNIP3L SIRT3 0 0 341 346 1 2
    BNIP3L HELLS 0 0 134 171 1 1
    BNIP3L MAPK3 0 0 161 161 1 2
    BNIP3L KEAP1 0 0 265 265 1 2
    BNIP3L PPP6C 0 0 61 202 1 1
    BNIP3L CASP4 0 0 95 209 1 2
    BNIP3L PARP1 0 0 152 179 1 2
    BNIP3L KCNH2 0 0 0 181 1 1
    BNIP3L CREG1 0 0 0 197 1 1
    BNIP3L ADM 0 0 125 181 1 1
    BNIP3L HSPA8 0 0 310 309 1 2
    BNIP3L BID 0 0 171 179 1 1
    BNIP3L EPB42 0 0 142 160 1 1
    BNIP3L ATG9A 0 0 258 332 1 2
    BNIP3L NKRF 0 0 96 193 1 1
    BNIP3L CDKN1A 0 0 164 163 1 2
    BNIP3L ZNF746 0 0 252 252 1 1
    BNIP3L UBE2N 0 0 0 190 1 1
    BNIP3L BAX 0 0 180 192 1 2
    BNIP3L CUL3 0 0 165 183 1 1
    BNIP3L CITED2 0 0 243 320 1 1
    BNIP3L PGAM2 0 0 57 152 1 1
    BNIP3L TOMM40 0 0 140 167 1 1
    BNIP3L CDO1 0 0 60 270 1 1
    BNIP3L ATG16L1 0 0 469 479 1 2
    BNIP3L BCL10 0 0 170 221 1 1
    BNIP3L HUNK 0 0 70 163 1 1
    BNIP3L PHC3 0 0 0 187 1 1
    BNIP3L PHB2 0 0 392 392 1 1
    BNIP3L VPS16 0 0 123 174 1 1
    BNIP3L GABARAPL1 299 800 818 974 1 2
    BNIP3L RALB 0 0 112 175 1 1
    BNIP3L MYO19 274 0 0 274 1 1
    BNIP3L MXI1 0 0 304 373 1 1
    BNIP3L HDAC1 0 0 142 159 1 2
    BNIP3L SIRT7 0 0 246 252 1 1
    BNIP3L METTL4 0 0 71 215 1 1
    BNIP3L SMCO4 462 0 0 461 1 1
    BNIP3L LOXL2 0 0 186 206 1 1
    BNIP3L MIEF2 0 0 381 381 1 1
    BNIP3L GATA1 0 0 226 226 1 1
    BNIP3L ENSG00000158164 0 0 172 190 1 1
    BNIP3L FUT11 0 0 154 153 1 1
    BNIP3L PPARGC1B 0 0 137 176 1 1
    BNIP3L ZNF205 0 0 166 165 1 1
    BNIP3L DAPK2 0 0 96 187 1 2
    BNIP3L MAVS 0 0 167 173 1 1
    BNIP3L EGLN2 0 0 261 277 1 1
    BNIP3L ATG7 0 0 639 647 1 2
    BNIP3L MAP1LC3C 0 0 372 412 1 2
    BNIP3L FECH 0 0 134 194 1 1
    BNIP3L TRADD 0 0 228 289 1 1
    BNIP3L MRPS7 0 0 0 156 1 1
    BNIP3L CHRM3 0 0 0 208 1 1
    BNIP3L DUSP8 0 0 51 152 1 1
    BNIP3L RAB9B 0 0 93 514 1 1
    BNIP3L DDX58 0 0 139 235 1 1
    BNIP3L FATE1 115 0 90 160 1 1
    BNIP3L SIRT6 0 0 243 249 1 1
    BNIP3L ALCAM 0 0 0 216 1 1
    BNIP3L IGF2 0 0 137 172 1 1
    BNIP3L BCL2L13 0 0 610 628 1 1
    BNIP3L CTSD 0 0 206 206 1 2
    BNIP3L TRIM63 0 0 260 315 1 1
    BNIP3L EIF3F 0 0 72 169 1 1
    BNIP3L TOMM70A 0 0 235 242 1 1
    BNIP3L ATM 0 0 218 222 1 1
    BNIP3L RAB32 0 0 150 157 1 2
    BNIP3L KCNA3 0 0 0 156 1 1
    BNIP3L IDH1 0 0 122 153 1 1
    BNIP3L TRIM32 0 0 66 173 1 1
    BNIP3L BCL2L10 0 0 282 341 1 1
    BNIP3L LGALS8 0 0 164 167 1 1
    BNIP3L EP300 0 0 185 185 1 1
    BNIP3L CCDC115 0 0 112 175 1 1
    BNIP3L NGFR 270 0 285 455 1 1
    BNIP3L AUP1 0 0 296 323 1 1
    BNIP3L BAG1 0 0 245 244 1 2
    BNIP3L TP53BP2 0 0 217 318 1 1
    BNIP3L SREBF1 0 0 88 181 1 2
    BNIP3L FAM134B 0 0 392 392 1 1
    BNIP3L BIRC3 0 0 248 257 1 1
    BNIP3L COX8A 0 0 169 174 1 1
    BNIP3L LDHA 0 0 425 437 1 1
    BNIP3L MAP3K3 0 0 84 319 1 1
    BNIP3L BPGM 0 0 163 214 1 1
    BNIP3L AMBRA1 0 0 601 601 1 2
    BNIP3L PHACTR1 0 0 0 190 1 1
    BNIP3L TP53AIP1 0 0 180 179 1 1
    BNIP3L UBE2QL1 0 0 0 157 1 1
    BNIP3L C12orf5 0 0 298 298 1 1
    BNIP3L FAM169A 0 0 113 206 1 1
    BNIP3L SNCAIP 0 0 150 304 1 2
    BNIP3L ERO1L 0 0 211 245 1 1
    BNIP3L PLCL2 0 0 66 151 1 1
    BNIP3L TNFRSF10A 0 0 201 201 1 1
    BNIP3L RHOT2 117 0 184 261 1 1
    BNIP3L BAG2 0 0 160 165 1 1
    BNIP3L CASP5 0 0 181 284 1 1
    BNIP3L DNM1L 0 0 523 529 1 2
    BNIP3L WIPI1 0 0 454 469 1 2
    BNIP3L CARD17 0 0 0 214 1 1
    BNIP3L SLC25A37 0 0 163 335 1 1
    BNIP3L CASP8 0 0 283 546 1 2
    BNIP3L GADD45GIP1 0 0 76 328 1 1
    BNIP3L ALB 0 0 182 181 1 1
    BNIP3L KIAA0226 0 0 294 294 1 1
    BNIP3L CD200 0 0 62 158 1 1
    BNIP3L CDK19 0 0 0 210 1 1
    BNIP3L VEGFA 0 0 290 290 1 1
    BNIP3L PGK1 0 0 277 295 1 2
    BNIP3L SLC2A14 0 0 167 167 1 1
    BNIP3L SLC10A6 0 0 73 155 1 1
    BNIP3L GABARAP 270 800 987 998 1 2
    BNIP3L PTEN 0 0 391 404 1 2
    BNIP3L CASP7 0 0 260 353 1 1
    BNIP3L CYFIP2 0 0 181 181 1 1
    BNIP3L HIPK2 0 0 129 188 1 1
    BNIP3L HSPA4 0 0 182 181 1 1
    BNIP3L KCNH6 0 0 46 186 1 1
    BNIP3L GBE1 0 0 108 184 1 1
    BNIP3L XBP1 0 0 160 171 1 2
    BNIP3L RIOK3 0 0 54 169 1 1
    BNIP3L UBE2Q1 0 0 0 236 1 1
    BNIP3L ATG5 0 0 636 682 1 2
    BNIP3L RPTOR 0 0 292 307 1 2
    BNIP3L HSPB3 0 0 438 438 1 1
    BNIP3L CALCOCO2 0 0 681 681 1 2
    BNIP3L PDCD4 0 0 125 155 1 1
    BNIP3L TBC1D5 0 0 234 234 1 2
    BNIP3L PPARA 0 0 146 204 1 1
    BNIP3L TIA1 0 0 66 216 1 1
    BNIP3L BCL2L14 0 0 234 245 1 1
    BNIP3L HIF1AN 0 0 208 208 1 1
    BNIP3L NIPSNAP1 0 0 181 191 1 1
    BNIP3L IER3 0 0 157 209 1 1
    BNIP3L MIEF1 0 0 337 337 1 1
    BNIP3L ATG4A 0 0 164 204 1 2
    BNIP3L CASP9 0 0 279 409 1 1
    BNIP3L ITPR1 0 0 182 183 1 2
    BNIP3L TBC1D15 0 0 181 198 1 1
    BNIP3L MAP3K5 0 0 155 154 1 1
    BNIP3L OPTN 0 0 652 672 1 2
    BNIP3L TRAF6 0 0 181 191 1 2
    BNIP3L CYCS 0 0 466 465 1 1
    BNIP3L COPS5 0 0 0 202 1 1
    BNIP3L HMGB1 0 0 171 189 1 2
    BNIP3L IMMT 0 0 163 169 1 1
    BNIP3L AFG3L2 0 0 122 160 1 1
    BNIP3L CTSB 0 0 217 234 1 2
    BNIP3L FUNDC2 0 0 90 340 1 1
    BNIP3L UBE2Q2 0 0 92 277 1 1
    BNIP3L SH3GLB1 0 0 337 351 1 2
    BNIP3L PAWR 0 0 42 302 1 1
    BNIP3L TMEM178B 0 0 140 366 1 1
    BNIP3L SMARCA4 270 0 0 270 1 1
    BNIP3L SIRT1 0 0 343 348 1 2
    BNIP3L MCL1 0 0 451 471 1 2
    BNIP3L ETS1 0 0 97 196 1 1
    BNIP3L BFAR 0 0 126 193 1 1
    BNIP3L BHLHE40 0 0 108 163 1 1
    BNIP3L ADIPOQ 186 0 49 192 1 1
    BNIP3L SH3RF1 0 0 702 806 1 1
    BNIP3L PEX5 0 0 180 179 1 1
    BNIP3L DEDD2 0 0 141 364 1 1
    BNIP3L MAPK8 0 0 261 261 1 2
    BNIP3L PTP4A1 0 0 67 377 1 1
    BNIP3L NUFIP1 0 0 134 152 1 1
    BNIP3L CA12 0 0 166 167 1 1
    BNIP3L ULK1 0 0 595 611 1 2
    BNIP3L API5 0 0 103 262 1 1
    BNIP3L ENO2 0 0 134 188 1 1
    BNIP3L TUFM 0 0 140 232 1 1
    BNIP3L MAP1LC3B 270 0 793 943 1 2
    BNIP3L ZNF846 0 0 165 165 1 1
    BNIP3L SESN2 0 0 318 332 1 2
    BNIP3L IFIH1 0 0 72 325 1 1
    BNIP3L RPS5 0 0 0 156 1 1
    BNIP3L DIABLO 0 0 245 244 1 1
    BNIP3L ATG10 0 0 466 497 1 2
    BNIP3L SPATA7 274 0 0 274 1 1
    BNIP3L USP30 0 0 407 417 1 1
    BNIP3L PMPCB 0 0 137 190 1 1
    BNIP3L RT14 0 0 166 165 1 1
    BNIP3L PEG10 0 0 72 150 1 1
    BNIP3L PAQR9 0 0 81 165 1 1
    BNIP3L CASP16 0 0 0 161 1 1
    BNIP3L MCM2 0 0 0 330 1 1
    BNIP3L SMARCB1 270 0 72 391 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0005521 Molecular Function lamin binding enables IDA
    GO:0005521 Molecular Function lamin binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0042803 Molecular Function protein homodimerization activity enables IDA
    GO:0071456 Biological Process cellular response to hypoxia acts_upstream_of_or_within IGI
    GO:0051607 Biological Process defense response to virus involved_in IBA
    GO:0051607 Biological Process defense response to virus involved_in IDA
    GO:0097345 Biological Process mitochondrial outer membrane permeabilization involved_in IBA
    GO:0035694 Biological Process mitochondrial protein catabolic process involved_in IMP
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in IDA
    GO:0010917 Biological Process negative regulation of mitochondrial membrane potential involved_in IEA
    GO:0043069 Biological Process negative regulation of programmed cell death acts_upstream_of_or_within IGI
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
    GO:0016239 Biological Process positive regulation of macroautophagy acts_upstream_of_or_within IGI
    GO:1901524 Biological Process regulation of mitophagy involved_in IEA
    GO:0043067 Biological Process regulation of programmed cell death involved_in IBA
    GO:1903214 Biological Process regulation of protein targeting to mitochondrion involved_in IEA
    GO:0005783 Cellular Component endoplasmic reticulum is_active_in IBA
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0016020 Cellular Component membrane located_in TAS
    GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IBA
    GO:0005741 Cellular Component mitochondrial outer membrane located_in IMP
    GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
    GO:0005739 Cellular Component mitochondrion located_in HTP
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0005635 Cellular Component nuclear envelope is_active_in IBA
    GO:0005635 Cellular Component nuclear envelope located_in IDA
    GO:0016607 Cellular Component nuclear speck located_in IDA
    GO:0005634 Cellular Component nucleus is_active_in IBA
    Pathways
    Name DB ID
    Generic Transcription Pathway Reactome R-HSA-212436
    Transcriptional Regulation by TP53 Reactome R-HSA-3700989
    TP53 Regulates Transcription of Cell Death Genes Reactome R-HSA-5633008
    TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Reactome R-HSA-6803204
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Gene expression (Transcription) Reactome R-HSA-74160
    Photodynamic therapy-induced HIF-1 survival signaling (WP3614) WikiPathways WP3614_r106542
    Apoptosis (WP254) WikiPathways WP254_r118382
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_004331 3 mRNA transcript variant 1 NC_000008 Reference
    NM_001330491 2 mRNA transcript variant 2 NC_000008 Reference