MLST8

MTOR associated protein, LST8 homolog
General Information
Name MTOR associated protein, LST8 homolog
Alias
  • target of rapamycin complex subunit LST8
  • TORC subunit LST8
  • gable
  • mammalian lethal with SEC13 protein 8
  • protein GbetaL
Synonyms Lst8 Pop3 GBL GbetaL LST8 POP3 WAT1
Gene_family WD repeat domain containing|MTOR complex 1|MTOR complex 2
organism Homo sapiens
entrez_id 64223
location 16p13.3
transcript_count 15
exon_count 9
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Enables protein serine/threonine kinase activator activity and protein-macromolecule adaptor activity. Involved in TOR signaling; positive regulation of TOR signaling; and regulation of actin cytoskeleton organization. Part of TORC1 complex and TORC2 complex. [provided by Alliance of Genome Resources, Mar 2025]
      Stringdb Target of rapamycin complex subunit LST8; Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1- mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up- [...]
      nextProt Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. MTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. MTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). MTORC1 phosphorylates and activates S6K1 at 'Thr-389', which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. MTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. MTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. MTORC2 promotes the serum-induced formation of stress-fibers or F-actin. MTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. MTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. MTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    MLST8 BioGRID XPO7 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ARGFX GeneID BioGRID Proximity Label-MS
    MLST8 BioGRID LCOR GeneID BioGRID Two-hybrid
    MLST8 BioGRID MTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
    MLST8 BioGRID RICTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
    MLST8 BioGRID RPTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification
    MLST8 BioGRID RPS6KA3 GeneID BioGRID Biochemical Activity
    MLST8 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID SLC38A7 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID PLEKHM1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    MLST8 BioGRID WDR5 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID NUMB GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID CDK2 GeneID BioGRID Biochemical Activity
    MLST8 BioGRID CDK1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
    MLST8 BioGRID FBXW7 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    MLST8 BioGRID EGFR GeneID BioGRID Negative Genetic
    MLST8 BioGRID COPB2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID MAPKAP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    MLST8 BioGRID NBR1 GeneID BioGRID Proximity Label-MS
    MLST8 BioGRID SERP2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCDC167 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID XXYLT1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID VOPP1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CYB5B GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CLMP GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID PDCL3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID SAV1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ANKRD49 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TRAPPC2L GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TRMT2A GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID NPTN GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ZNF609 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT5 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID GPR182 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID KDELR2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ILVBL GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT8 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT6B GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT4 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT7 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID STUB1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID HELZ GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID BAG3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID BAG5 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID MPZL1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID RUVBL1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TUBA1A GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TCP1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TCF7L2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID SCN2B GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID HSPA6 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID HSPA2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID HSPA1B GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID FPR1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ETV3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID EP300 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CD40 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID CCT6A GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID LNPK GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    MLST8 BioGRID E7 GeneID BioGRID Two-hybrid
    MLST8 BioGRID BCAR1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID FASN GeneID BioGRID Positive Genetic
    MLST8 BioGRID MCAM GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA
    MLST8 BioGRID WIPI2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID LARP1 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID OTUD7B GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID ZUP1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
    MLST8 BioGRID XPO4 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID THADA GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID XPO6 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID PRAME GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID LYPLA2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID MELK GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID SLC30A4 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID TUBA4A GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID FOXF2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ACAT2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ZNRF2 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID MTMR3 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID KIF11 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID Srp72 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID Cct8 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID Cct4 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID Cct3 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID Cct2 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID APPL2 GeneID BioGRID Two-hybrid
    MLST8 BioGRID EIF4EBP1 GeneID BioGRID Biochemical Activity
    MLST8 BioGRID USP54 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID DYNC2I1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID SETX GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID KEAP1 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID PFDN5 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
    MLST8 BioGRID MOV10 GeneID BioGRID Affinity Capture-RNA
    MLST8 BioGRID FKBP8 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID SUZ12 GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID PRMT1 GeneID BioGRID Two-hybrid
    MLST8 BioGRID STAT1 GeneID BioGRID Co-fractionation
    MLST8 BioGRID ATXN1 GeneID BioGRID Two-hybrid
    MLST8 BioGRID A2M GeneID BioGRID Two-hybrid
    MLST8 BioGRID DEPTOR GeneID BioGRID Affinity Capture-MS
    MLST8 BioGRID ULK1 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID Cul4a GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID Dtl GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID Rptor GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID Mtor GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID PRR5 GeneID BioGRID Affinity Capture-Western
    MLST8 BioGRID KRT85 GeneID BioGRID Affinity Capture-MS
    MLST8 None RPTOR GeneID HPRD None
    MLST8 None MTOR GeneID HPRD None
    MLST8 Protein RHEB GeneID BIND GBL (LST8) interacts with Rheb.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    MLST8 BCAT2 0 0 122 226 1 1
    MLST8 DDIT4 0 0 469 481 1 1
    MLST8 UBFD1 0 0 0 173 1 1
    MLST8 RHEB 800 900 861 998 1 2
    MLST8 TLDC1 0 0 124 313 1 1
    MLST8 RNASEL 0 0 0 219 1 1
    MLST8 FEM1B 0 0 0 190 1 1
    MLST8 PHLPP2 0 0 206 288 1 1
    MLST8 ANKRD10 0 0 0 248 1 1
    MLST8 MAP2K2 0 0 0 156 1 1
    MLST8 NAA20 0 0 86 156 1 1
    MLST8 SZT2 0 900 155 914 1 1
    MLST8 GNB2L1 0 0 82 234 1 1
    MLST8 DNAJB2 0 0 0 169 1 1
    MLST8 RAB34 0 0 57 265 1 1
    MLST8 ANKRD50 0 0 0 248 1 1
    MLST8 DNAJB12 0 0 0 169 1 1
    MLST8 RRAS2 0 0 0 167 1 1
    MLST8 ANK2 0 0 0 190 1 1
    MLST8 BARD1 0 0 0 248 1 1
    MLST8 ARID4A 0 0 0 156 1 1
    MLST8 PTOV1 0 0 0 198 1 1
    MLST8 ENO4 0 0 0 169 1 1
    MLST8 PDPK1 0 0 455 681 1 2
    MLST8 CYC1 0 0 0 197 1 1
    MLST8 NUBP2 0 0 0 265 1 1
    MLST8 CCT6A 0 0 60 228 1 1
    MLST8 MAP4K3 0 0 268 268 1 1
    MLST8 DNAJB7 0 0 0 169 1 1
    MLST8 CHMP1A 0 0 0 344 1 1
    MLST8 IPMK 0 0 249 265 1 1
    MLST8 SESN1 0 900 335 931 1 2
    MLST8 NTRK1 0 0 143 154 1 1
    MLST8 WDR37 0 0 0 335 1 1
    MLST8 KCNA1 0 0 310 309 1 1
    MLST8 PIK3C2B 0 0 150 459 1 1
    MLST8 PRMT8 0 0 0 177 1 1
    MLST8 IRS1 0 900 525 950 1 1
    MLST8 SGK1 0 900 683 980 1 1
    MLST8 RPS9 154 0 61 171 1 1
    MLST8 RPS6KB1 0 900 801 987 1 2
    MLST8 ANKRD18A 0 0 0 248 1 1
    MLST8 YWHAQ 0 900 75 917 1 1
    MLST8 KAT2B 0 0 74 230 1 1
    MLST8 REM1 0 0 0 248 1 1
    MLST8 WDR86 0 0 0 376 1 1
    MLST8 CDK1 0 0 140 171 1 1
    MLST8 EIF4E 0 900 681 973 1 1
    MLST8 PRKDC 0 0 194 717 1 2
    MLST8 PPP2CA 0 0 82 403 1 1
    MLST8 ETV6 0 0 0 206 1 1
    MLST8 PRKAA1 0 900 124 924 1 2
    MLST8 CCND1 0 0 320 337 1 1
    MLST8 ACTA2 0 0 0 153 1 1
    MLST8 ANKRD37 0 0 0 248 1 1
    MLST8 ULK3 0 0 73 251 1 2
    MLST8 FLT3LG 0 0 307 307 1 1
    MLST8 NOS3 0 0 125 260 1 1
    MLST8 ANKDD1B 0 0 0 190 1 1
    MLST8 GID4 0 0 135 224 1 1
    MLST8 ATP6V1F 0 600 0 639 1 1
    MLST8 PRPF19 0 0 0 379 1 1
    MLST8 WDR77 0 0 0 311 1 1
    MLST8 ATR 0 0 210 497 1 1
    MLST8 C17orf97 0 0 158 157 1 1
    MLST8 ANKRD62 0 0 0 248 1 1
    MLST8 RAB7A 0 0 246 284 1 2
    MLST8 PPEF2 0 0 0 197 1 1
    MLST8 DRAM1 0 0 201 201 1 2
    MLST8 FNBP1L 0 0 0 174 1 1
    MLST8 LAMTOR2 0 600 406 770 1 1
    MLST8 FKBP1C 0 0 120 381 1 1
    MLST8 SUPT5H 0 0 0 222 1 1
    MLST8 PLEKHA4 270 0 0 270 1 1
    MLST8 RPS6KA2 0 0 341 342 1 1
    MLST8 U2AF2 0 0 0 299 1 1
    MLST8 ASB11 0 0 0 248 1 1
    MLST8 PPP6R3 0 0 92 186 1 1
    MLST8 NFKB2 0 0 0 248 1 1
    MLST8 ATG4B 0 0 139 313 1 2
    MLST8 TCP1 0 0 48 160 1 1
    MLST8 SOS1 0 0 95 342 1 1
    MLST8 PIK3C2G 0 0 108 432 1 1
    MLST8 ATP12A 0 0 134 150 1 1
    MLST8 LAMTOR3 0 600 391 747 1 1
    MLST8 POTEI 0 0 0 153 1 1
    MLST8 PPP2R1A 0 0 91 218 1 1
    MLST8 MAPK1 0 0 112 252 1 2
    MLST8 CCDC144A 0 0 0 248 1 1
    MLST8 NDUFV1 0 0 0 177 1 1
    MLST8 IGF1 0 0 464 463 1 1
    MLST8 WDFY3 0 0 150 239 1 2
    MLST8 UVRAG 0 0 322 321 1 2
    MLST8 RHEBL1 0 0 268 293 1 1
    MLST8 NEDD4L 0 0 187 200 1 1
    MLST8 CCND3 0 0 138 159 1 1
    MLST8 ANKRD60 0 0 0 190 1 1
    MLST8 RFXANK 0 0 0 220 1 1
    MLST8 TAF5 0 0 0 224 1 1
    MLST8 PPP6R1 0 0 97 210 1 1
    MLST8 FBXW2 0 0 0 355 1 1
    MLST8 ANKRD27 0 0 0 190 1 1
    MLST8 CCT2 303 0 0 385 1 1
    MLST8 PGK2 0 0 0 226 1 1
    MLST8 SLC1A5 0 0 173 179 1 1
    MLST8 TOR2A 0 0 0 164 1 1
    MLST8 ANKRD26 0 0 0 190 1 1
    MLST8 USP5 0 0 0 165 1 1
    MLST8 ANKRD1 0 0 0 248 1 1
    MLST8 KANK4 0 0 0 190 1 1
    MLST8 HIPK3 0 0 164 263 1 1
    MLST8 PIK3R2 0 0 283 304 1 1
    MLST8 ANKLE1 0 0 0 190 1 1
    MLST8 ASCL4 0 0 0 183 1 1
    MLST8 ASB15 0 0 0 248 1 1
    MLST8 STK32C 0 0 0 381 1 1
    MLST8 VPS11 0 0 150 181 1 2
    MLST8 LARS 0 0 377 466 1 1
    MLST8 ANKRD9 0 0 0 248 1 1
    MLST8 UQCRC1 0 0 0 166 1 1
    MLST8 PAFAH1B1 0 0 0 193 1 1
    MLST8 NHLRC1 0 0 47 401 1 1
    MLST8 STIP1 0 0 0 170 1 1
    MLST8 RRS1 0 0 0 275 1 1
    MLST8 IGBP1 0 800 0 932 1 1
    MLST8 USP14 0 0 0 210 1 1
    MLST8 FNIP2 0 0 218 250 1 1
    MLST8 EEF2 0 0 371 409 1 1
    MLST8 ETV3 172 0 0 171 1 1
    MLST8 KIAA1024 0 0 46 166 1 1
    MLST8 ANKRD36 0 0 0 248 1 1
    MLST8 BAHD1 0 0 0 160 1 1
    MLST8 WIPI2 270 0 152 423 1 2
    MLST8 XPO6 214 0 0 214 1 1
    MLST8 SGK3 0 0 197 527 1 1
    MLST8 RPL26 0 0 88 252 1 1
    MLST8 ATF4 0 0 182 224 1 2
    MLST8 UQCRFS1 0 0 0 152 1 1
    MLST8 RAE1 0 0 0 405 1 1
    MLST8 NUDT12 0 0 0 248 1 1
    MLST8 AKT1 0 900 756 979 1 2
    MLST8 AAMP 0 0 0 426 1 1
    MLST8 PPARG 0 0 212 212 1 1
    MLST8 AP2M1 0 0 0 188 1 1
    MLST8 UBLCP1 0 0 0 173 1 1
    MLST8 CLPP 0 0 53 155 1 1
    MLST8 PREX2 0 0 273 350 1 1
    MLST8 KLHDC9 0 0 0 161 1 1
    MLST8 ANKS6 0 0 0 248 1 1
    MLST8 SPATA5L1 0 0 0 263 1 1
    MLST8 MRPS34 0 0 0 162 1 1
    MLST8 VMP1 0 0 138 224 1 2
    MLST8 PPP2R4 0 0 511 584 1 1
    MLST8 CRAMP1L 0 0 0 248 1 1
    MLST8 THOC6 0 0 0 164 1 1
    MLST8 SLC36A1 0 0 389 402 1 1
    MLST8 WSB1 0 0 0 191 1 1
    MLST8 SPATA5 0 0 0 263 1 1
    MLST8 ENSG00000144785 0 0 0 160 1 1
    MLST8 ATP7A 0 0 150 177 1 1
    MLST8 PSMD8 0 0 0 185 1 1
    MLST8 TNKS2 0 0 0 190 1 1
    MLST8 IKBKB 0 0 448 456 1 1
    MLST8 ANKRD30B 0 0 0 248 1 1
    MLST8 DNAJB14 0 0 0 169 1 1
    MLST8 SEH1L 0 900 284 935 1 1
    MLST8 FEM1C 0 0 0 190 1 1
    MLST8 FOXO4 0 0 213 222 1 1
    MLST8 ANK3 0 0 0 190 1 1
    MLST8 FEM1A 0 0 0 220 1 1
    MLST8 TOR4A 0 0 0 164 1 1
    MLST8 EIF4EBP1 847 900 818 997 1 1
    MLST8 ANKRD65 0 0 0 190 1 1
    MLST8 TYMS 0 0 0 248 1 1
    MLST8 ADRM1 0 0 0 225 1 1
    MLST8 SLC7A2 0 0 0 156 1 1
    MLST8 CDC16 0 0 216 256 1 1
    MLST8 PINK1 0 0 161 168 1 2
    MLST8 GSK3A 0 0 74 225 1 1
    MLST8 PPP3CA 0 0 0 197 1 1
    MLST8 SIRT4 0 0 259 279 1 1
    MLST8 FOXF2 271 0 0 271 1 1
    MLST8 PSMC1 0 0 0 435 1 1
    MLST8 ERBB2 0 0 219 219 1 2
    MLST8 RHD 0 0 171 171 1 1
    MLST8 ASB14 0 0 0 248 1 1
    MLST8 FBXO25 0 0 72 227 1 1
    MLST8 ANKRA2 0 0 0 190 1 1
    MLST8 SCGN 0 0 45 467 1 1
    MLST8 GRK5 0 0 92 232 1 1
    MLST8 SRGAP3 0 0 0 150 1 1
    MLST8 ATP6V1A 0 600 0 650 1 1
    MLST8 ANKRD6 0 0 0 248 1 1
    MLST8 SRC 0 0 255 265 1 1
    MLST8 MPHOSPH8 0 0 0 320 1 1
    MLST8 TTC12 0 0 0 179 1 1
    MLST8 EMG1 0 0 0 243 1 1
    MLST8 RCC2 0 0 0 156 1 1
    MLST8 CDC42 0 0 193 218 1 1
    MLST8 ATG4C 0 0 122 256 1 2
    MLST8 SLK 0 0 134 185 1 1
    MLST8 WDR24 0 900 391 929 1 1
    MLST8 ACTG2 0 0 0 153 1 1
    MLST8 CCT3 130 0 0 232 1 1
    MLST8 DHFRL1 0 0 0 242 1 1
    MLST8 YWHAB 0 900 0 914 1 1
    MLST8 SLC2A4 0 0 161 161 1 1
    MLST8 CUX2 0 0 0 207 1 1
    MLST8 FOXO3 0 0 424 478 1 2
    MLST8 EIF2AK3 0 0 166 165 1 2
    MLST8 CASKIN1 0 0 0 190 1 1
    MLST8 ALYREF 0 0 95 166 1 1
    MLST8 ACLY 0 0 176 182 1 1
    MLST8 PAK1IP1 0 0 0 391 1 1
    MLST8 TAF4 0 0 0 208 1 1
    MLST8 ASB9 0 0 0 248 1 1
    MLST8 TRIM28 0 0 67 174 1 2
    MLST8 ANKRD17 0 0 60 263 1 1
    MLST8 RABGEF1 0 0 0 190 1 1
    MLST8 FBXW9 0 0 60 153 1 1
    MLST8 ATG3 0 0 266 293 1 2
    MLST8 NOP58 0 0 46 283 1 1
    MLST8 DNAJB1 0 0 0 319 1 2
    MLST8 PSMB5 0 0 0 208 1 1
    MLST8 COASY 0 0 0 153 1 1
    MLST8 TXNDC9 0 0 136 154 1 1
    MLST8 MCRS1 0 0 95 195 1 1
    MLST8 PSMD7 0 0 0 152 1 1
    MLST8 FBXW11 0 0 0 206 1 1
    MLST8 LYPLA2 278 0 0 293 1 1
    MLST8 NUBP1 0 0 0 155 1 1
    MLST8 RAC2 0 0 400 418 1 1
    MLST8 DNAJC21 0 0 0 169 1 1
    MLST8 YY1 0 900 150 911 1 1
    MLST8 PLRG1 0 0 0 448 1 1
    MLST8 EIF2S1 0 0 241 330 1 2
    MLST8 SKP1 0 0 151 150 1 1
    MLST8 RRAGA 800 900 596 995 1 2
    MLST8 MITF 0 0 108 248 1 1
    MLST8 MDH2 0 0 54 165 1 1
    MLST8 RPL26L1 0 0 0 177 1 1
    MLST8 TCHP 0 0 216 216 1 1
    MLST8 SEC13 0 900 561 989 1 1
    MLST8 MRPS2 0 0 0 163 1 1
    MLST8 WDR83 0 0 0 232 1 1
    MLST8 ZFYVE1 0 0 202 202 1 2
    MLST8 BOLA2-SMG1P6 0 0 0 663 1 1
    MLST8 CDKN1B 0 0 213 213 1 2
    MLST8 GLUL 0 0 73 166 1 1
    MLST8 BNIP3L 0 0 184 183 1 2
    MLST8 TAF5L 0 0 0 232 1 1
    MLST8 MAF1 0 900 218 928 1 1
    MLST8 HACE1 0 0 0 194 1 1
    MLST8 RAB7B 0 0 241 251 1 1
    MLST8 TRRAP 0 0 475 666 1 1
    MLST8 TSC2 0 900 792 988 1 2
    MLST8 DDB1 0 0 324 324 1 1
    MLST8 PIK3C2A 0 0 109 433 1 2
    MLST8 VDAC1 0 0 442 442 1 2
    MLST8 ATG12 0 0 329 340 1 2
    MLST8 TONSL 0 0 0 253 1 1
    MLST8 PSMA5 0 0 0 209 1 1
    MLST8 ETV7 0 0 150 169 1 1
    MLST8 PFDN4 0 0 0 323 1 1
    MLST8 EBF3 0 0 355 367 1 1
    MLST8 MAPK15 0 0 0 158 1 2
    MLST8 ISYNA1 0 0 94 160 1 1
    MLST8 ENSG00000268643 0 0 0 198 1 1
    MLST8 PRR5L 154 900 701 972 1 1
    MLST8 ANKRD63 0 0 0 248 1 1
    MLST8 ASZ1 0 0 0 248 1 1
    MLST8 PSMC4 0 0 0 450 1 1
    MLST8 PSMB6 0 0 0 295 1 1
    MLST8 ATG101 0 800 391 881 1 2
    MLST8 TRIB3 0 0 77 159 1 1
    MLST8 CPSF4 0 0 59 221 1 1
    MLST8 RNF152 0 0 180 179 1 1
    MLST8 FCHSD1 0 0 0 199 1 1
    MLST8 ATG4D 0 0 113 277 1 2
    MLST8 UPF2 0 0 73 166 1 1
    MLST8 CASP3 0 0 255 254 1 2
    MLST8 PSMB9 0 0 0 259 1 1
    MLST8 GAPVD1 0 0 0 190 1 1
    MLST8 ATP6V1B2 0 600 126 751 1 1
    MLST8 MKS1 0 0 183 248 1 1
    MLST8 EIF4B 0 0 550 566 1 1
    MLST8 DNAJC22 0 0 0 169 1 1
    MLST8 PIK3CD 0 0 321 568 1 1
    MLST8 TBC1D7 0 0 560 573 1 2
    MLST8 ATG16L1 0 0 270 265 1 2
    MLST8 DHFR 0 0 0 242 1 1
    MLST8 ECSIT 0 0 0 153 1 1
    MLST8 PI4KA 0 0 0 390 1 1
    MLST8 WDR61 0 0 0 213 1 1
    MLST8 KIDINS220 0 0 0 190 1 1
    MLST8 SLC30A4 234 0 0 234 1 1
    MLST8 FBP1 0 0 49 184 1 1
    MLST8 PSMD3 0 0 0 382 1 1
    MLST8 MORF4L1 0 0 0 183 1 1
    MLST8 BDH1 0 0 0 153 1 1
    MLST8 POC1A 0 0 0 218 1 1
    MLST8 YWHAH 0 900 0 914 1 1
    MLST8 LAMTOR1 0 600 469 897 1 1
    MLST8 PHB2 0 0 0 183 1 1
    MLST8 GSK3B 0 0 222 349 1 2
    MLST8 ATP6V1E2 0 600 0 617 1 1
    MLST8 SFN 0 900 0 913 1 1
    MLST8 CDKN2A 0 0 155 337 1 2
    MLST8 PPP6C 0 0 160 607 1 1
    MLST8 ANKRD29 0 0 0 248 1 1
    MLST8 JAZF1 0 0 0 232 1 1
    MLST8 ANKS4B 0 0 0 248 1 1
    MLST8 CHUK 0 0 456 463 1 1
    MLST8 PFDN6 0 0 0 215 1 1
    MLST8 AP5S1 0 0 134 163 1 1
    MLST8 NDUFS8 0 0 0 166 1 1
    MLST8 ATP6V1C1 0 600 45 623 1 1
    MLST8 USF2 0 0 0 191 1 1
    MLST8 RAI14 0 0 0 190 1 1
    MLST8 BTRC 0 0 183 251 1 1
    MLST8 ANKEF1 0 0 0 190 1 1
    MLST8 MTPN 0 0 0 190 1 1
    MLST8 EIF4A2 0 0 401 412 1 1
    MLST8 FKBP10 0 0 0 219 1 1
    MLST8 LANCL1 0 0 0 193 1 1
    MLST8 ANKRD53 0 0 0 190 1 1
    MLST8 RPF1 0 0 0 154 1 1
    MLST8 NRAS 0 0 95 214 1 1
    MLST8 CHMP5 0 0 60 257 1 1
    MLST8 TFE3 0 0 170 300 1 1
    MLST8 GNB3 0 0 0 219 1 1
    MLST8 CDK9 0 0 444 444 1 1
    MLST8 THEM4 0 0 195 195 1 1
    MLST8 ASB2 0 0 0 248 1 1
    MLST8 ASPSCR1 0 0 0 183 1 1
    MLST8 KRAS 0 0 190 297 1 1
    MLST8 FOXO1 0 0 459 459 1 2
    MLST8 WDR59 0 900 305 934 1 1
    MLST8 ACAT2 287 0 0 301 1 1
    MLST8 ANKRD32 0 0 0 310 1 1
    MLST8 CCT7 239 0 0 344 1 1
    MLST8 NUBPL 0 0 0 155 1 1
    MLST8 YWHAZ 0 900 46 915 1 1
    MLST8 RRAGC 800 900 692 995 1 1
    MLST8 DEPTOR 486 900 989 999 1 1
    MLST8 SUCLG2 0 0 218 218 1 1
    MLST8 NKPD1 0 0 0 190 1 1
    MLST8 ZNRF2 270 0 72 323 1 1
    MLST8 ASB5 0 0 0 248 1 1
    MLST8 POC1B 0 0 0 209 1 1
    MLST8 PSMD9 0 0 0 203 1 1
    MLST8 RRAGD 0 900 519 967 1 1
    MLST8 RNF20 0 0 0 167 1 1
    MLST8 DNAJB9 0 0 0 169 1 2
    MLST8 LPIN1 0 0 335 346 1 2
    MLST8 ASB8 0 0 0 248 1 1
    MLST8 FKBP9 0 0 0 164 1 1
    MLST8 ATP6V0A4 0 0 150 215 1 1
    MLST8 CCT6B 237 0 0 373 1 1
    MLST8 DNAJB6 0 0 0 169 1 1
    MLST8 CLMP 234 0 0 234 1 1
    MLST8 EEF2K 0 0 401 435 1 2
    MLST8 ATP6V0E1 0 600 0 600 1 1
    MLST8 EIF4EBP2 0 0 459 643 1 1
    MLST8 BECN1 0 0 413 412 1 2
    MLST8 OTUD7B 270 0 205 394 1 1
    MLST8 FBXL19 0 0 0 152 1 1
    MLST8 KANK2 0 0 0 190 1 1
    MLST8 PAIP1 0 0 53 156 1 1
    MLST8 LRRK2 0 0 62 159 1 2
    MLST8 CDKN2C 0 0 0 248 1 1
    MLST8 CAD 0 0 143 176 1 1
    MLST8 MET 0 0 124 178 1 1
    MLST8 MAPK11 0 0 123 396 1 1
    MLST8 PEA15 0 0 54 153 1 1
    MLST8 AUH 0 0 60 224 1 1
    MLST8 CDKN2B 0 0 49 254 1 1
    MLST8 TRIP10 0 0 0 161 1 1
    MLST8 PIK3CB 0 0 325 570 1 1
    MLST8 ESR1 0 0 157 156 1 1
    MLST8 MAPK6 0 0 0 158 1 1
    MLST8 TOR3A 0 0 0 164 1 1
    MLST8 PSMD12 0 0 0 324 1 1
    MLST8 ATAD1 0 0 0 227 1 1
    MLST8 PIM2 0 0 181 254 1 2
    MLST8 RBBP4 0 0 0 321 1 1
    MLST8 PPP1CA 0 0 0 229 1 1
    MLST8 PDIK1L 0 0 0 193 1 1
    MLST8 TRPA1 0 0 0 190 1 1
    MLST8 ANKMY2 0 0 0 190 1 1
    MLST8 PSMC5 0 0 0 241 1 1
    MLST8 KIF13B 0 0 0 400 1 1
    MLST8 EOMES 0 0 323 323 1 1
    MLST8 MCL1 0 0 212 212 1 2
    MLST8 UNKL 0 0 0 324 1 1
    MLST8 SIRT1 0 0 272 319 1 2
    MLST8 DDIT4L 0 0 184 183 1 1
    MLST8 SLX4 0 0 0 188 1 1
    MLST8 MIB1 0 0 0 248 1 1
    MLST8 BAHCC1 0 0 90 473 1 1
    MLST8 GNB1L 0 0 0 332 1 1
    MLST8 PRKAG2 0 900 60 919 1 1
    MLST8 ATP4A 0 0 134 150 1 1
    MLST8 PUM1 0 0 0 308 1 1
    MLST8 XBP1 0 0 123 172 1 2
    MLST8 ASB3 0 0 0 248 1 1
    MLST8 TANC2 0 0 0 248 1 1
    MLST8 HIPK2 0 0 0 155 1 1
    MLST8 ANKRD22 0 0 0 248 1 1
    MLST8 WDR18 0 0 74 316 1 1
    MLST8 YIPF1 0 0 367 382 1 1
    MLST8 PPP5D1 0 0 0 197 1 1
    MLST8 KSR1 0 0 150 161 1 1
    MLST8 ATG5 0 0 341 467 1 2
    MLST8 TBCA 0 0 82 223 1 1
    MLST8 NFKBIB 0 0 0 248 1 1
    MLST8 HHAT 0 0 60 316 1 1
    MLST8 MAP1LC3B 0 0 262 326 1 2
    MLST8 KPTN 0 900 178 916 1 1
    MLST8 MCAM 270 0 0 270 1 1
    MLST8 TERT 0 0 74 222 1 1
    MLST8 DYRK1A 0 0 66 177 1 1
    MLST8 ESPN 0 0 0 286 1 1
    MLST8 ATG10 0 0 255 254 1 2
    MLST8 AKT3 0 900 390 946 1 1
    MLST8 SLC7A14 0 0 0 156 1 1
    MLST8 FN1 0 0 151 150 1 1
    MLST8 FNIP1 0 0 365 430 1 1
    MLST8 TBP 0 0 57 204 1 1
    MLST8 RALA 0 0 96 158 1 1
    MLST8 WDR88 0 0 0 182 1 1
    MLST8 TIAL1 0 0 82 151 1 1
    MLST8 STXBP4 0 0 50 610 1 1
    MLST8 NUDC 130 0 0 254 1 1
    MLST8 RIPK4 0 0 0 248 1 1
    MLST8 EIF4G2 0 0 95 194 1 1
    MLST8 ULK1 270 900 600 974 1 2
    MLST8 PRKCA 0 900 602 958 1 1
    MLST8 RPS6KA1 0 0 517 518 1 1
    MLST8 ANKRD24 0 0 0 190 1 1
    MLST8 DNAJB8 0 0 0 169 1 1
    MLST8 ANKDD1A 0 0 0 190 1 1
    MLST8 ENSG00000267261 0 0 0 179 1 1
    MLST8 TTI1 0 900 961 997 1 1
    MLST8 POLI 0 0 202 202 1 1
    MLST8 DNAJB13 0 0 0 313 1 1
    MLST8 ANKRD61 0 0 0 190 1 1
    MLST8 DAP 0 0 282 282 1 2
    MLST8 PRKAG3 0 900 63 917 1 1
    MLST8 CASKIN2 0 0 0 206 1 1
    MLST8 WDR55 0 0 0 221 1 1
    MLST8 ANKRD18B 0 0 0 248 1 1
    MLST8 ATM 0 0 335 450 1 1
    MLST8 SHC1 0 0 164 186 1 1
    MLST8 EIF3F 0 0 234 377 1 1
    MLST8 TBL3 0 0 0 291 1 1
    MLST8 TRIM63 0 0 171 171 1 1
    MLST8 CECR2 0 0 0 165 1 1
    MLST8 PREB 0 0 63 184 1 1
    MLST8 IGF2 0 0 166 276 1 1
    MLST8 RAB41 0 0 0 258 1 1
    MLST8 SNX17 0 0 0 152 1 1
    MLST8 TIPRL 0 0 195 329 1 1
    MLST8 STRAP 0 0 0 247 1 1
    MLST8 PSMB10 0 0 0 185 1 1
    MLST8 ATP6V0A1 0 0 144 213 1 1
    MLST8 PSMB7 0 0 0 185 1 1
    MLST8 NCK1 0 0 0 181 1 1
    MLST8 ACTG1 0 0 0 153 1 1
    MLST8 PSMB11 0 0 0 156 1 1
    MLST8 SNRNP40 0 0 0 208 1 1
    MLST8 PREX1 0 0 323 416 1 1
    MLST8 DYRK1B 0 0 0 155 1 1
    MLST8 ATG7 0 0 374 518 1 2
    MLST8 ANKRD20A3 0 0 0 248 1 1
    MLST8 PRKAA2 0 900 357 944 1 2
    MLST8 TELO2 0 900 529 977 1 1
    MLST8 RRAGB 0 900 564 975 1 2
    MLST8 PI4KB 0 0 0 390 1 1
    MLST8 TRAF7 0 0 0 291 1 1
    MLST8 WIPI1 0 0 289 364 1 2
    MLST8 PTEN 0 0 527 609 1 2
    MLST8 DYRK4 0 0 0 155 1 1
    MLST8 GABARAP 0 0 202 236 1 2
    MLST8 MAPK7 0 0 73 219 1 1
    MLST8 VEGFA 0 0 277 277 1 1
    MLST8 FKBP2 0 0 161 288 1 1
    MLST8 WSB2 0 0 0 214 1 1
    MLST8 SREBF1 0 900 323 929 1 2
    MLST8 SLC36A4 0 0 397 410 1 1
    MLST8 MARK2 0 0 245 244 1 1
    MLST8 BUB3 0 0 0 363 1 1
    MLST8 FAM173A 0 0 0 186 1 1
    MLST8 MAPK14 0 0 96 377 1 1
    MLST8 RANBP10 0 0 76 655 1 1
    MLST8 EIF4EBP3 0 0 396 531 1 1
    MLST8 CTTNBP2 0 0 0 190 1 1
    MLST8 WDR1 0 0 0 173 1 1
    MLST8 PSMC3 0 0 0 413 1 1
    MLST8 EIF4E1B 0 0 0 206 1 1
    MLST8 GNB4 0 0 0 218 1 1
    MLST8 RHOT2 0 0 0 166 1 1
    MLST8 LEP 0 0 170 169 1 1
    MLST8 NFKBIA 0 0 96 291 1 1
    MLST8 PRAME 211 0 0 211 1 1
    MLST8 AMBRA1 0 0 325 339 1 2
    MLST8 LDHA 0 0 117 161 1 1
    MLST8 ATAD2B 0 0 0 263 1 1
    MLST8 APAF1 0 0 61 153 1 1
    MLST8 MKNK1 0 0 155 154 1 1
    MLST8 ASB6 0 0 0 248 1 1
    MLST8 PAAF1 0 0 0 210 1 1
    MLST8 SLC7A4 0 0 0 156 1 1
    MLST8 EIF3H 0 0 73 383 1 1
    MLST8 ANKRD30BL 0 0 0 248 1 1
    MLST8 NPRL2 0 900 378 965 1 1
    MLST8 PSMD10 0 0 0 190 1 1
    MLST8 DAW1 0 0 0 198 1 1
    MLST8 ANKRD42 0 0 0 248 1 1
    MLST8 MELK 275 0 47 343 1 1
    MLST8 CAMKK2 0 0 350 404 1 2
    MLST8 SRSF1 0 0 81 157 1 1
    MLST8 NDUFS1 0 0 0 182 1 1
    MLST8 UACA 0 0 0 190 1 1
    MLST8 LAMTOR4 0 600 450 775 1 1
    MLST8 NSA2 0 0 72 215 1 1
    MLST8 ERN1 0 0 147 158 1 2
    MLST8 PRPF31 0 0 0 155 1 1
    MLST8 ASB1 0 0 0 248 1 1
    MLST8 STAT3 0 0 218 218 1 2
    MLST8 PPP1R12C 0 0 51 198 1 1
    MLST8 CPVL 0 0 0 157 1 1
    MLST8 GABPB2 0 0 0 190 1 1
    MLST8 C7orf60 0 900 181 914 1 1
    MLST8 ATP6V0D1 0 600 46 629 1 1
    MLST8 EIF4G3 0 0 74 205 1 1
    MLST8 EIF2AK4 0 0 283 490 1 1
    MLST8 MKKS 0 0 0 153 1 1
    MLST8 ATP6V0C 0 600 42 630 1 2
    MLST8 MSL3 0 0 0 156 1 1
    MLST8 ENSG00000273637 0 0 0 384 1 1
    MLST8 RNF40 0 0 0 167 1 1
    MLST8 TP53 0 0 342 342 1 2
    MLST8 STX5 0 0 0 165 1 1
    MLST8 MDM2 0 0 250 250 1 1
    MLST8 TRIM16 0 0 60 301 1 2
    MLST8 GART 0 0 0 162 1 1
    MLST8 KANK1 0 0 0 190 1 1
    MLST8 CDK4 0 0 150 157 1 1
    MLST8 EGFR 0 0 318 317 1 1
    MLST8 HTT 0 0 305 305 1 1
    MLST8 PPP1CC 0 0 53 207 1 1
    MLST8 TOR1A 0 0 0 317 1 1
    MLST8 ASB7 0 0 0 190 1 1
    MLST8 LAMP1 0 0 145 167 1 2
    MLST8 SLC2A1 0 0 194 194 1 1
    MLST8 ANKFY1 0 0 60 296 1 1
    MLST8 PPP1R27 0 0 0 190 1 1
    MLST8 HK2 0 0 269 270 1 1
    MLST8 ANKS1A 0 0 0 190 1 1
    MLST8 VKORC1L1 0 0 0 197 1 1
    MLST8 BRSK1 0 0 0 155 1 1
    MLST8 RAF1 0 0 245 261 1 2
    MLST8 MCAT 0 0 0 227 1 1
    MLST8 MAP1A 0 0 112 207 1 1
    MLST8 RAB10 0 0 248 248 1 1
    MLST8 NFKBIZ 0 0 0 248 1 1
    MLST8 HSPBP1 0 0 0 158 1 1
    MLST8 SLC7A5 0 0 261 286 1 1
    MLST8 KLHDC2 0 0 0 161 1 1
    MLST8 CTSA 0 0 0 157 1 1
    MLST8 TFEC 0 0 49 447 1 1
    MLST8 ANKRD35 0 0 0 190 1 1
    MLST8 EIF5B 0 0 113 266 1 1
    MLST8 SRGAP2 0 0 0 150 1 1
    MLST8 PPP3CC 0 0 0 197 1 1
    MLST8 ASB4 0 0 0 248 1 1
    MLST8 MYCN 0 0 124 155 1 1
    MLST8 ITFG2 0 900 164 912 1 1
    MLST8 ANKRD16 0 0 0 248 1 1
    MLST8 NGDN 0 0 603 603 1 1
    MLST8 GOLPH3 0 0 260 276 1 1
    MLST8 VPS39 0 0 283 440 1 1
    MLST8 ANKRD7 0 0 0 248 1 1
    MLST8 ACTA1 0 0 0 153 1 1
    MLST8 SHANK1 0 0 0 248 1 1
    MLST8 DRG2 0 0 0 174 1 1
    MLST8 EFNA5 0 0 423 422 1 1
    MLST8 HIPK4 0 0 0 155 1 1
    MLST8 AKT2 0 900 409 947 1 1
    MLST8 THOC3 0 0 0 431 1 1
    MLST8 ENSG00000272772 0 0 0 372 1 1
    MLST8 FKBP11 0 0 0 164 1 1
    MLST8 EIF2B5 0 0 91 223 1 1
    MLST8 RB1CC1 0 900 504 948 1 2
    MLST8 FBXW8 0 0 184 201 1 1
    MLST8 CAB39 0 0 234 254 1 1
    MLST8 LARP1 59 0 275 288 1 1
    MLST8 UNK 0 0 67 710 1 1
    MLST8 BOLA2 0 0 0 663 1 1
    MLST8 ODC1 0 0 184 183 1 1
    MLST8 YRDC 0 0 0 303 1 1
    MLST8 MAP2K1 0 0 213 213 1 1
    MLST8 PPIF 0 0 0 153 1 1
    MLST8 CDKN2D 0 0 0 248 1 1
    MLST8 FKBP7 0 0 113 226 1 1
    MLST8 STK11 0 0 517 560 1 2
    MLST8 ANKS1B 0 0 0 190 1 1
    MLST8 ASNA1 0 0 0 179 1 1
    MLST8 PPIP5K1 0 0 155 174 1 1
    MLST8 SLC6A4 0 0 0 369 1 1
    MLST8 PPP1R16A 0 0 0 210 1 1
    MLST8 ILK 0 0 261 398 1 1
    MLST8 WDR12 0 0 0 394 1 1
    MLST8 PPP5C 0 0 0 220 1 1
    MLST8 STK32B 0 0 0 367 1 1
    MLST8 HIPK1 0 0 0 155 1 1
    MLST8 ARL8B 0 0 139 165 1 1
    MLST8 PPP1R7 0 0 51 213 1 1
    MLST8 ITGAE 0 0 294 294 1 1
    MLST8 MYC 0 0 549 549 1 2
    MLST8 PDK1 0 0 100 191 1 1
    MLST8 ANKRD28 0 0 63 265 1 1
    MLST8 PPARGC1A 0 900 267 925 1 1
    MLST8 ANKRD20A4 0 0 0 248 1 1
    MLST8 PI3 0 0 185 185 1 1
    MLST8 USF1 0 0 0 191 1 1
    MLST8 IGF1R 0 0 330 339 1 1
    MLST8 ATP6V1G3 0 600 0 600 1 1
    MLST8 FBP2 0 0 0 178 1 1
    MLST8 PPP3CB 0 0 0 197 1 1
    MLST8 DVL1 0 0 62 174 1 1
    MLST8 RUVBL2 0 0 93 235 1 1
    MLST8 PIK3R3 0 0 208 208 1 1
    MLST8 FANK1 0 0 0 248 1 1
    MLST8 FKBP1B 0 0 0 325 1 1
    MLST8 RICTOR 972 900 989 999 1 2
    MLST8 STOML1 0 0 109 163 1 1
    MLST8 SLC7A1 0 0 54 167 1 1
    MLST8 LSM5 0 0 0 224 1 1
    MLST8 RPL27 0 0 0 214 1 1
    MLST8 ATP6V1G1 0 600 0 600 1 1
    MLST8 CDC40 0 0 0 301 1 1
    MLST8 PIK3CA 0 0 334 576 1 2
    MLST8 ATP6V1C2 0 600 0 621 1 1
    MLST8 LONRF2 0 0 0 238 1 1
    MLST8 FBXO42 0 0 0 161 1 1
    MLST8 ARHGAP4 0 0 0 150 1 1
    MLST8 PHLPP1 0 0 289 333 1 1
    MLST8 PIK3R4 0 0 334 359 1 2
    MLST8 RAB40AL 0 0 164 163 1 1
    MLST8 BCL2L1 0 0 266 266 1 2
    MLST8 STRADA 0 0 234 310 1 1
    MLST8 PPP1R12B 0 0 0 190 1 1
    MLST8 NFKB1 0 0 0 248 1 1
    MLST8 FCHSD2 0 0 0 199 1 1
    MLST8 ATG14 0 0 390 390 1 2
    MLST8 ESPL1 0 0 0 248 1 1
    MLST8 LARS2 0 0 343 498 1 1
    MLST8 GAPDH 0 0 264 302 1 2
    MLST8 SLC25A11 0 0 0 256 1 1
    MLST8 PML 0 900 0 900 1 1
    MLST8 ENO1 0 0 53 203 1 1
    MLST8 CHMP1B 0 0 0 341 1 1
    MLST8 NF1 0 0 217 217 1 1
    MLST8 MAP2K7 0 0 325 325 1 1
    MLST8 BRSK2 0 0 58 170 1 1
    MLST8 POTEE 0 0 0 153 1 1
    MLST8 SMG1 0 0 469 813 1 1
    MLST8 RPS6KA5 0 0 47 151 1 1
    MLST8 KHDRBS2 0 0 155 170 1 1
    MLST8 PRR5 154 900 988 999 1 1
    MLST8 FKBP8 270 0 701 801 1 1
    MLST8 GPS1 0 0 49 219 1 1
    MLST8 GABARAPL2 0 0 298 328 1 2
    MLST8 KATNB1 0 0 0 196 1 1
    MLST8 IGFBP5 0 0 0 207 1 1
    MLST8 ARF1 0 0 183 208 1 1
    MLST8 ANKRD20A1 0 0 0 248 1 1
    MLST8 CLIP1 0 900 66 908 1 1
    MLST8 MAPK4 0 0 0 158 1 1
    MLST8 GRB10 0 0 390 390 1 1
    MLST8 ESRRA 0 0 321 333 1 1
    MLST8 CREB1 0 0 157 156 1 1
    MLST8 NSF 0 0 124 266 1 1
    MLST8 SH3GLB2 0 0 74 213 1 1
    MLST8 ANKRD20A2 0 0 0 248 1 1
    MLST8 FBXO32 0 0 218 239 1 2
    MLST8 PRPF4 0 0 0 215 1 1
    MLST8 LAMTOR5 0 600 325 724 1 1
    MLST8 SLC38A9 0 600 451 777 1 1
    MLST8 PTGES2 0 0 0 151 1 1
    MLST8 HSPD1 0 0 0 153 1 1
    MLST8 NKTR 0 0 48 233 1 1
    MLST8 CS 0 0 81 223 1 1
    MLST8 WDR53 0 0 0 228 1 1
    MLST8 ANXA5 0 0 162 161 1 1
    MLST8 MAP1LC3B2 0 0 115 192 1 2
    MLST8 RRN3 0 900 135 913 1 1
    MLST8 HSF1 0 900 0 906 1 1
    MLST8 UBE2B 0 0 0 311 1 1
    MLST8 TANC1 0 0 0 248 1 1
    MLST8 C12orf66 0 900 202 916 1 1
    MLST8 PPP2R2A 0 0 113 174 1 1
    MLST8 SIRT2 0 0 247 268 1 2
    MLST8 ATP6V0E2 0 600 0 608 1 1
    MLST8 NOTCH1 0 0 166 165 1 1
    MLST8 ARAF 0 0 125 155 1 1
    MLST8 PRMT1 43 0 0 224 1 1
    MLST8 PIDD1 0 0 0 271 1 1
    MLST8 ANKRD52 0 0 0 248 1 1
    MLST8 FLAD1 0 0 0 154 1 1
    MLST8 POTEF 0 0 0 153 1 1
    MLST8 MTMR3 270 0 108 321 1 2
    MLST8 PSMC6 0 0 0 183 1 1
    MLST8 MAPKAP1 891 900 989 999 1 1
    MLST8 MTOR 981 900 989 999 1 2
    MLST8 ANKS3 0 0 0 248 1 1
    MLST8 ATP5D 0 0 0 179 1 1
    MLST8 TRIM59 0 0 96 491 1 1
    MLST8 TBL1XR1 0 0 0 231 1 1
    MLST8 IGFBP7 0 0 0 356 1 1
    MLST8 TTC33 0 0 0 174 1 1
    MLST8 CCDC124 0 0 0 160 1 1
    MLST8 ANKAR 0 0 0 190 1 1
    MLST8 PPP1R12A 0 0 47 195 1 1
    MLST8 MAP3K2 0 0 97 151 1 1
    MLST8 PPP4C 0 0 47 202 1 1
    MLST8 CHMP2B 0 0 57 160 1 2
    MLST8 PIK3C3 0 0 501 709 1 2
    MLST8 RPS6 0 0 650 831 1 1
    MLST8 ENSG00000115239 0 0 0 248 1 1
    MLST8 UBE2A 0 0 0 231 1 1
    MLST8 PLEK 0 0 580 580 1 1
    MLST8 BRD2 0 0 267 286 1 1
    MLST8 STAT1 270 0 74 295 1 1
    MLST8 HHATL 0 0 0 185 1 1
    MLST8 DNAJB4 0 0 0 313 1 1
    MLST8 FOXO6 0 0 171 171 1 1
    MLST8 SCPEP1 0 0 0 213 1 1
    MLST8 WDSUB1 0 0 0 402 1 1
    MLST8 GATSL2 0 900 233 920 1 1
    MLST8 ANKRD23 0 0 0 248 1 1
    MLST8 PSMC2 0 0 0 163 1 1
    MLST8 BTD 0 0 0 160 1 1
    MLST8 ASB18 0 0 0 248 1 1
    MLST8 RAB5A 0 0 142 150 1 2
    MLST8 CCT5 0 0 0 153 1 1
    MLST8 PRKCB 0 0 82 231 1 2
    MLST8 ATP6V1H 0 600 0 636 1 1
    MLST8 HIF1A 0 0 373 373 1 2
    MLST8 SIRT5 0 0 231 263 1 1
    MLST8 SH3BP4 0 0 220 220 1 1
    MLST8 SLC1A7 0 0 321 321 1 1
    MLST8 SEC24B 0 0 45 151 1 1
    MLST8 NFKBID 0 0 0 248 1 1
    MLST8 ATXN1 192 0 61 208 1 1
    MLST8 ARF3 0 0 170 195 1 1
    MLST8 MAPK13 0 0 0 192 1 1
    MLST8 KANK3 0 0 0 190 1 1
    MLST8 RAB6B 0 0 0 258 1 1
    MLST8 NDRG1 0 0 235 240 1 1
    MLST8 CCDC25 0 0 0 266 1 1
    MLST8 EIF3I 0 0 0 405 1 1
    MLST8 MRPL12 0 0 0 151 1 1
    MLST8 ATP6V1B1 0 600 86 739 1 1
    MLST8 CTNNB1 0 0 217 217 1 1
    MLST8 MAP1LC3A 0 0 169 220 1 2
    MLST8 WDR5B 0 0 0 195 1 1
    MLST8 HRAS 0 0 240 360 1 1
    MLST8 CDK2 0 0 210 238 1 1
    MLST8 PACS2 0 0 74 170 1 1
    MLST8 PRKAG1 0 900 49 917 1 1
    MLST8 SRGAP2C 0 0 0 150 1 1
    MLST8 MCCC1 0 0 48 213 1 1
    MLST8 TGFBRAP1 0 0 74 213 1 1
    MLST8 PASK 0 0 0 198 1 1
    MLST8 DNAJB5 0 0 0 313 1 1
    MLST8 INS 0 0 519 519 1 1
    MLST8 ATG13 0 900 566 972 1 2
    MLST8 ACTB 0 0 286 369 1 1
    MLST8 SGTB 0 0 0 183 1 1
    MLST8 SLC7A3 0 0 0 156 1 1
    MLST8 CSTF1 0 0 0 302 1 1
    MLST8 ATP6V1G2 0 600 0 600 1 1
    MLST8 STUB1 0 0 54 176 1 2
    MLST8 RANBP9 0 0 0 443 1 1
    MLST8 KEAP1 129 0 134 233 1 2
    MLST8 MAPK3 0 0 314 463 1 2
    MLST8 SIRT3 0 0 228 249 1 2
    MLST8 ENO3 0 0 0 173 1 1
    MLST8 UTP15 0 0 0 414 1 1
    MLST8 BNIP3 0 0 261 261 1 2
    MLST8 SQSTM1 270 0 320 482 1 2
    MLST8 ARID4B 0 0 0 156 1 1
    MLST8 TFEB 0 0 427 527 1 2
    MLST8 BCL3 0 0 0 248 1 1
    MLST8 TBL2 0 0 0 381 1 1
    MLST8 UFD1L 0 0 0 236 1 1
    MLST8 HSP90AA1 0 0 213 249 1 2
    MLST8 ANKHD1-EIF4EBP3 0 0 0 248 1 1
    MLST8 ANKRD2 0 0 0 248 1 1
    MLST8 KLHDC1 0 0 0 161 1 1
    MLST8 FBXW7 0 0 142 481 1 1
    MLST8 WDR82 0 0 0 416 1 1
    MLST8 ZNF704 0 0 0 155 1 1
    MLST8 DHX57 0 0 325 748 1 1
    MLST8 TOR1B 0 0 0 317 1 1
    MLST8 KIF13A 0 0 49 615 1 1
    MLST8 PKD1L3 0 0 0 204 1 1
    MLST8 DYRK2 0 0 48 161 1 1
    MLST8 PACRG 0 0 56 207 1 1
    MLST8 RAB1A 0 0 164 163 1 2
    MLST8 BCL10 0 0 53 154 1 1
    MLST8 USP6 0 0 241 240 1 1
    MLST8 ATP6V0B 0 600 0 608 1 1
    MLST8 CCT4 0 0 0 153 1 1
    MLST8 GTF3C1 0 0 164 163 1 1
    MLST8 SIRT7 0 0 233 254 1 1
    MLST8 NMD3 0 0 81 222 1 1
    MLST8 EIF3E 0 0 74 216 1 1
    MLST8 RALB 0 0 71 169 1 1
    MLST8 ATP6V1E1 0 600 0 617 1 1
    MLST8 PDK2 0 0 324 393 1 1
    MLST8 WDR38 0 0 0 215 1 1
    MLST8 GABARAPL1 0 0 310 340 1 2
    MLST8 GNB1 0 0 0 219 1 1
    MLST8 SPP1 0 0 90 155 1 1
    MLST8 GATSL3 0 900 323 929 1 1
    MLST8 CDKN1A 0 0 170 169 1 2
    MLST8 PEX7 0 0 0 374 1 1
    MLST8 ENSG00000249884 0 0 0 194 1 1
    MLST8 ATG9A 0 0 141 189 1 2
    MLST8 EIF4G1 0 0 517 580 1 2
    MLST8 RHOA 0 0 211 283 1 1
    MLST8 ABTB1 0 0 0 233 1 1
    MLST8 ANKRD49 0 0 0 190 1 1
    MLST8 TOMM40 0 0 0 198 1 1
    MLST8 GABPB1 0 0 0 190 1 1
    MLST8 KLHDC10 0 0 0 161 1 1
    MLST8 SLC38A2 0 0 122 168 1 1
    MLST8 ESPNL 0 0 0 248 1 1
    MLST8 FKBP14 0 0 0 164 1 1
    MLST8 DEPDC5 0 900 341 937 1 1
    MLST8 IRS2 0 0 280 280 1 1
    MLST8 CLIP4 0 0 0 307 1 1
    MLST8 PUM2 0 0 0 308 1 1
    MLST8 SRGAP2B 0 0 0 150 1 1
    MLST8 PSMB8 0 0 0 185 1 1
    MLST8 ENSG00000270024 0 0 150 499 1 1
    MLST8 TCIRG1 0 600 134 662 1 1
    MLST8 FZR1 0 0 0 389 1 1
    MLST8 LAMP2 43 0 270 271 1 2
    MLST8 YWHAE 0 900 48 915 1 1
    MLST8 VCP 0 0 0 338 1 2
    MLST8 ASB16 0 0 0 248 1 1
    MLST8 ANKRD36B 0 0 0 248 1 1
    MLST8 ANK1 0 0 0 190 1 1
    MLST8 SNX27 0 0 48 168 1 1
    MLST8 GRB2 0 0 164 163 1 1
    MLST8 NFKBIE 0 0 0 248 1 1
    MLST8 ANKRD44 0 0 0 248 1 1
    MLST8 ATAD3A 0 0 0 151 1 1
    MLST8 NPRL3 0 900 335 961 1 1
    MLST8 EIF1 0 0 158 215 1 1
    MLST8 USH1G 0 0 0 248 1 1
    MLST8 NCK2 0 0 0 286 1 1
    MLST8 ANKRD36C 0 0 0 248 1 1
    MLST8 MIB2 0 0 0 248 1 1
    MLST8 TBL1X 0 0 57 236 1 1
    MLST8 FKBP3 0 0 0 169 1 1
    MLST8 ANKHD1 0 0 0 248 1 1
    MLST8 MAPK12 0 0 107 285 1 1
    MLST8 WDR31 0 0 0 405 1 1
    MLST8 PFDN2 0 0 0 197 1 1
    MLST8 POLDIP3 0 0 341 345 1 1
    MLST8 MTHFD2 0 0 141 180 1 1
    MLST8 SLC16A4 0 0 76 155 1 1
    MLST8 TNKS 0 0 0 190 1 1
    MLST8 KIF11 259 0 0 272 1 1
    MLST8 TSC1 0 900 681 973 1 2
    MLST8 RABEPK 0 0 0 161 1 1
    MLST8 PPP1R16B 0 0 0 190 1 1
    MLST8 BCL2L11 0 0 210 210 1 1
    MLST8 WDR5 0 0 0 224 1 1
    MLST8 RPL7 0 0 94 253 1 1
    MLST8 LOH12CR1 0 0 62 155 1 1
    MLST8 JUN 0 0 215 215 1 1
    MLST8 ASB13 0 0 0 248 1 1
    MLST8 EIF2AK1 0 0 108 282 1 1
    MLST8 AKT1S1 800 900 989 999 1 1
    MLST8 CHEK1 0 0 150 467 1 1
    MLST8 MVP 0 0 444 444 1 1
    MLST8 CDC20 0 0 60 459 1 1
    MLST8 PIK3CG 0 0 460 656 1 1
    MLST8 ULK2 0 900 334 943 1 2
    MLST8 ZFP36 0 0 66 322 1 1
    MLST8 DHX36 0 0 0 189 1 1
    MLST8 APPL2 170 0 0 169 1 1
    MLST8 MAPK9 0 0 124 164 1 2
    MLST8 CIAO1 0 0 0 446 1 1
    MLST8 CYCS 63 0 150 169 1 1
    MLST8 RPS6KA3 0 0 337 341 1 1
    MLST8 TRAF6 0 0 180 179 1 2
    MLST8 SESN3 0 360 247 501 1 1
    MLST8 FLCN 0 0 401 763 1 1
    MLST8 FNBP1 0 0 0 166 1 1
    MLST8 ATG4A 0 0 85 241 1 2
    MLST8 FASN 62 0 125 186 1 1
    MLST8 SOS2 0 0 0 206 1 1
    MLST8 NACC1 0 0 64 639 1 1
    MLST8 GLUD2 0 0 0 156 1 1
    MLST8 PRKAB2 0 900 0 912 1 1
    MLST8 EGF 0 0 260 260 1 1
    MLST8 TNRC18 0 0 0 209 1 1
    MLST8 IGFBP1 0 0 61 317 1 1
    MLST8 ASB10 0 0 0 248 1 1
    MLST8 NRARP 0 0 46 194 1 1
    MLST8 DYRK3 0 0 91 199 1 1
    MLST8 POTEJ 0 0 0 153 1 1
    MLST8 PIK3R1 0 0 289 289 1 1
    MLST8 HSPA4 0 0 288 304 1 1
    MLST8 ANKRD39 0 0 0 248 1 1
    MLST8 SRGAP1 0 0 0 150 1 1
    MLST8 ANKRD66 0 0 0 248 1 1
    MLST8 ZUFSP 270 0 0 270 1 1
    MLST8 ATP6V1D 0 600 0 600 1 1
    MLST8 SPRYD3 0 0 0 303 1 1
    MLST8 PDCD4 0 0 252 252 1 1
    MLST8 PSMD4 0 0 0 269 1 1
    MLST8 RPTOR 977 900 990 999 1 2
    MLST8 SURF1 0 0 101 183 1 1
    MLST8 PXN 0 0 415 414 1 1
    MLST8 ARHGEF3 0 0 233 261 1 1
    MLST8 ANKRD30A 0 0 0 248 1 1
    MLST8 NDUFS7 0 0 0 175 1 1
    MLST8 SESN2 0 900 390 936 1 2
    MLST8 TNS1 0 0 299 352 1 1
    MLST8 TUFM 0 0 0 165 1 1
    MLST8 RRP9 0 0 0 445 1 1
    MLST8 GLUD1 0 0 94 203 1 1
    MLST8 FKBP1A 0 0 888 921 1 2
    MLST8 PPP2CB 0 0 0 377 1 1
    MLST8 TDP2 0 0 235 235 1 1
    MLST8 PPP2R5B 0 0 90 194 1 1
    MLST8 RPS6KB2 0 600 502 878 1 2
    MLST8 POLR2E 0 0 0 247 1 1
    MLST8 SRD5A3 0 0 0 268 1 1
    MLST8 PRKAB1 0 900 150 922 1 2
    MLST8 HSF5 0 0 0 187 1 1
    MLST8 SKP2 0 0 180 179 1 1
    MLST8 MAPK8 0 0 217 217 1 2
    MLST8 RAB6A 0 0 0 258 1 1
    MLST8 RUVBL1 0 0 122 208 1 1
    MLST8 SAMD1 0 0 0 187 1 1
    MLST8 SHANK2 0 0 0 248 1 1
    MLST8 ENO2 0 0 0 173 1 1
    MLST8 PLD1 0 0 261 261 1 1
    MLST8 BCKDK 0 0 0 211 1 1
    MLST8 RAB36 0 0 0 253 1 1
    MLST8 ATP6V0A2 0 0 157 221 1 1
    MLST8 ATP6V0D2 0 600 47 643 1 1
    MLST8 SIRT6 0 0 233 273 1 1
    MLST8 DDX41 0 0 0 215 1 1
    MLST8 FKBP4 0 0 117 217 1 1
    MLST8 YWHAG 0 900 0 914 1 1
    MLST8 ACTC1 0 0 0 153 1 1
    MLST8 MAPKAPK2 0 0 96 162 1 1
    MLST8 RAP2B 0 0 181 209 1 1
    MLST8 SH3PXD2A 0 0 0 390 1 1
    MLST8 MORF4L2 0 0 0 156 1 1
    MLST8 RAB6C 0 0 0 258 1 1
    MLST8 WDR60 156 0 0 155 1 1
    MLST8 MIOS 0 900 325 939 1 1
    MLST8 ATG16L2 0 0 73 391 1 2
    MLST8 STK32A 0 0 0 367 1 1
    MLST8 BOLA2B 0 0 0 663 1 1
    MLST8 PIK3R5 0 0 167 167 1 1
    MLST8 PSMA4 0 0 0 215 1 1
    MLST8 FKBP5 0 0 90 173 1 1
    MLST8 SLC3A2 0 0 217 232 1 1
    MLST8 GLMN 0 0 172 171 1 1
    MLST8 PFDN5 129 0 0 174 1 1
    MLST8 PPP1CB 0 0 0 197 1 1
    MLST8 ZNF395 0 0 57 544 1 1
    MLST8 CHMP3 0 0 0 194 1 1
    MLST8 INVS 0 0 0 248 1 1
    MLST8 CUX1 0 0 0 207 1 1
    MLST8 GNB2 0 0 51 338 1 1
    MLST8 PPM1G 0 0 57 155 1 1
    MLST8 ALB 0 0 181 181 1 1
    MLST8 SGK2 0 0 134 490 1 1
    MLST8 EIF4A1 0 0 403 414 1 1
    MLST8 CD276 0 0 270 270 1 1
    MLST8 GNB5 0 0 0 215 1 1
    MLST8 CUL1 0 0 181 238 1 1
    MLST8 ERCC8 0 0 0 275 1 1
    MLST8 PPP6R2 0 0 67 163 1 1
    MLST8 BBS10 0 0 0 153 1 1
    MLST8 XPO4 214 0 0 214 1 1
    MLST8 EIF4E2 0 0 90 246 1 1
    MLST8 RAP2A 0 0 147 176 1 1
    MLST8 UBE2U 0 0 0 154 1 1
    MLST8 PGK1 0 0 92 267 1 2
    MLST8 ASB12 0 0 0 248 1 1
    MLST8 DNAJC18 0 0 0 169 1 1
    MLST8 SGTA 0 0 0 223 1 1
    MLST8 KAT2A 0 0 95 265 1 1
    MLST8 ARHGAP8 0 0 0 437 1 1
    MLST8 THADA 217 0 0 217 1 1
    MLST8 IL4 0 0 90 440 1 1
    MLST8 ENSG00000267318 0 0 0 367 1 1
    MLST8 SH3PXD2B 0 0 0 390 1 1
    MLST8 ANKRD55 0 0 0 248 1 1
    MLST8 ENSG00000248405 0 0 0 437 1 1
    MLST8 NLE1 0 0 0 239 1 1
    MLST8 ANKRD46 0 0 0 190 1 1
    MLST8 STK35 0 0 0 193 1 1
    MLST8 EP300 0 0 113 188 1 1
    MLST8 AGMAT 0 0 61 276 1 1
    MLST8 C18orf54 0 0 61 228 1 1
    MLST8 ANKRD54 0 0 0 248 1 1
    MLST8 MLLT4 0 0 0 256 1 1
    MLST8 PPEF1 0 0 0 197 1 1
    MLST8 TARBP2 0 0 0 323 1 1
    MLST8 SNCAIP 0 0 0 248 1 2
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0043539 Molecular Function protein serine/threonine kinase activator activity enables IDA
    GO:0030674 Molecular Function protein-macromolecule adaptor activity enables IDA
    GO:0006974 Biological Process DNA damage response involved_in NAS
    GO:0031929 Biological Process TOR signaling involved_in IBA
    GO:0038202 Biological Process TORC1 signaling involved_in IDA
    GO:0038202 Biological Process TORC1 signaling involved_in IMP
    GO:0038203 Biological Process TORC2 signaling involved_in IDA
    GO:0071456 Biological Process cellular response to hypoxia involved_in NAS
    GO:0031669 Biological Process cellular response to nutrient levels involved_in NAS
    GO:0071470 Biological Process cellular response to osmotic stress involved_in NAS
    GO:0007010 Biological Process cytoskeleton organization involved_in NAS
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in NAS
    GO:0010507 Biological Process negative regulation of autophagy involved_in NAS
    GO:0032008 Biological Process positive regulation of TOR signaling involved_in IMP
    GO:0030838 Biological Process positive regulation of actin filament polymerization involved_in IEA
    GO:0030307 Biological Process positive regulation of cell growth involved_in NAS
    GO:0045821 Biological Process positive regulation of glycolytic process involved_in NAS
    GO:0046889 Biological Process positive regulation of lipid biosynthetic process involved_in NAS
    GO:1905857 Biological Process positive regulation of pentose-phosphate shunt involved_in NAS
    GO:0032956 Biological Process regulation of actin cytoskeleton organization involved_in IBA
    GO:0032956 Biological Process regulation of actin cytoskeleton organization involved_in IMP
    GO:0031931 Cellular Component TORC1 complex part_of IBA
    GO:0031931 Cellular Component TORC1 complex part_of IDA
    GO:0031931 Cellular Component TORC1 complex part_of IPI
    GO:0031932 Cellular Component TORC2 complex part_of IBA
    GO:0031932 Cellular Component TORC2 complex part_of IDA
    GO:0031932 Cellular Component TORC2 complex part_of IPI
    GO:0005737 Cellular Component cytoplasm located_in ISS
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005765 Cellular Component lysosomal membrane located_in IEA
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:1902554 Cellular Component serine/threonine protein kinase complex part_of IDA
    Pathways
    Name DB ID
    Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
    p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
    Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850) WikiPathways WP3850_r121711
    Thermogenesis (WP4321) WikiPathways WP4321_r123362
    Fragile X syndrome (WP4549) WikiPathways WP4549_r124287
    Dravet syndrome (WP5200) WikiPathways WP5200_r124413
    Thyroid hormones production and peripheral downstream signaling effects (WP4746) WikiPathways WP4746_r123317
    Clear cell renal cell carcinoma pathways (WP4018) WikiPathways WP4018_r123404
    DYRK1A (WP5180) WikiPathways WP5180_r122423
    Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
    Regulatory circuits of the STAT3 signaling pathway (WP4538) WikiPathways WP4538_r104390
    Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway (WP4577) WikiPathways WP4577_r123500
    Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
    Autophagy (WP4923) WikiPathways WP4923_r110416
    Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
    Interferon type I signaling pathways (WP585) WikiPathways WP585_r107188
    PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    T-cell activation SARS-CoV-2 (WP5098) WikiPathways WP5098_r119538
    Angiopoietin-like protein 8 regulatory pathway (WP3915) WikiPathways WP3915_r123920
    Target of rapamycin signaling (WP1471) WikiPathways WP1471_r123616
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_147907 2 miscRNA transcript variant 11 NC_000016 Reference
    NR_147905 2 miscRNA transcript variant 9 NC_000016 Reference
    NR_147906 2 miscRNA transcript variant 10 NC_000016 Reference
    NR_147904 2 miscRNA transcript variant 8 NC_000016 Reference
    NM_001199174 3 mRNA transcript variant 3 NC_000016 Reference
    XM_005255475 4 mRNA transcript variant X1 NC_000016 Reference
    XM_047434466 1 mRNA transcript variant X2 NC_000016 Reference
    NM_001352059 2 mRNA transcript variant 6 NC_000016 Reference
    NM_001352057 2 mRNA transcript variant 5 NC_000016 Reference
    NM_022372 6 mRNA transcript variant 1 NC_000016 Reference
    NM_001199175 3 mRNA transcript variant 4 NC_000016 Reference
    NM_001352060 2 mRNA transcript variant 7 NC_000016 Reference
    XM_005255479 3 mRNA transcript variant X3 NC_000016 Reference
    NM_001199173 3 mRNA transcript variant 2 NC_000016 Reference
    XM_047434467 1 mRNA transcript variant X4 NC_000016 Reference