SCOC

short coiled-coil protein
General Information
Name short coiled-coil protein
Alias
  • short coiled-coil protein
Synonyms HRIHFB2072 SCOCO UNC-69
Gene_family None
organism Homo sapiens
entrez_id 60592
location 4q31.1
transcript_count 10
exon_count 8
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
      Stringdb Short coiled-coil protein; Positive regulator of amino acid starvation-induced autophagy; Belongs to the SCOC family
      nextProt Positive regulator of amino acid starvation-induced autophagy.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    SCOC BioGRID FGFR4 GeneID BioGRID Proximity Label-MS
    SCOC BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID MYC GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID MAPRE1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID RPS6KA4 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID H2BC21 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID NUMA1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID HMGA1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID BLOC1S2 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID SASS6 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID GCC1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID ATG16L1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID CCHCR1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID C21orf91 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    SCOC BioGRID NRBF2 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID SCHIP1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
    SCOC BioGRID HEATR5A GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID SNAPIN GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID TBC1D30 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID CASP8AP2 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID FEZ1 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    SCOC BioGRID FEZ2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    SCOC BioGRID BFSP2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    SCOC BioGRID LUZP1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID RBBP8 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID PAWR GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID DACH1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID EBAG9 GeneID BioGRID Proximity Label-MS
    SCOC BioGRID Srgap2 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID ESR1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID DDIT4L GeneID BioGRID Two-hybrid
    SCOC BioGRID SIKE1 GeneID BioGRID Two-hybrid
    SCOC BioGRID TRAPPC6A GeneID BioGRID Two-hybrid
    SCOC BioGRID KIFC3 GeneID BioGRID Two-hybrid
    SCOC BioGRID CLUAP1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID PSMC5 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
    SCOC BioGRID ORF17.5 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID ORF17 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID CROCC GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID SSNA1 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID DOK5 GeneID BioGRID Two-hybrid
    SCOC BioGRID TRMT112 GeneID BioGRID Co-fractionation
    SCOC BioGRID EPB41L3 GeneID BioGRID Affinity Capture-MS
    SCOC BioGRID HNRNPH1 GeneID BioGRID Co-fractionation
    SCOC BioGRID KRT40 GeneID BioGRID Two-hybrid
    SCOC BioGRID TCF4 GeneID BioGRID Two-hybrid
    SCOC BioGRID MAPK8 GeneID BioGRID Two-hybrid
    SCOC BioGRID ITSN1 GeneID BioGRID Two-hybrid
    SCOC None FEZ1 GeneID HPRD None
    SCOC None ARL1 GeneID HPRD None
    StringDB
    A B experiments database textmining combined score hadb nhadb
    SCOC PSTPIP1 0 0 123 361 1 1
    SCOC RFWD2 0 0 180 302 1 1
    SCOC ZYG11A 0 0 394 394 1 1
    SCOC HTT 0 0 108 152 1 1
    SCOC MFSD6 0 0 263 442 1 1
    SCOC HNRNPR 0 0 134 160 1 1
    SCOC VPS53 0 0 171 318 1 1
    SCOC CCNB1IP1 0 0 171 234 1 1
    SCOC AP3D1 0 0 0 368 1 1
    SCOC GPM6B 0 0 171 261 1 1
    SCOC RGS5 0 0 158 340 1 1
    SCOC ERC1 0 0 113 217 1 1
    SCOC PIK3C2B 0 0 141 166 1 1
    SCOC TUSC5 0 0 216 234 1 1
    SCOC FNBP4 0 0 96 152 1 1
    SCOC ACTR10 0 0 0 168 1 1
    SCOC AP1G2 0 0 0 157 1 1
    SCOC MED8 0 0 182 307 1 1
    SCOC CUL2 0 0 150 189 1 1
    SCOC PSTPIP2 0 0 0 210 1 1
    SCOC BRSK1 0 0 167 167 1 1
    SCOC RAB3IL1 0 0 233 261 1 1
    SCOC SGSM3 0 0 57 202 1 1
    SCOC TECPR1 0 0 194 249 1 2
    SCOC NDEL1 0 0 207 207 1 1
    SCOC PIP5KL1 0 0 0 175 1 1
    SCOC TNNC1 0 0 193 193 1 1
    SCOC DLGAP3 0 0 181 621 1 1
    SCOC MKNK1 0 0 276 276 1 1
    SCOC ITSN1 192 0 150 331 1 1
    SCOC RGS22 0 0 0 159 1 1
    SCOC RBM3 0 0 115 251 1 1
    SCOC KIF23 0 0 264 264 1 1
    SCOC SAP30L 0 0 253 414 1 1
    SCOC HSPA12B 0 0 0 267 1 1
    SCOC HTR3B 0 0 181 215 1 1
    SCOC GCH1 0 0 125 313 1 1
    SCOC TMEM258 0 0 228 227 1 1
    SCOC PLEKHJ1 0 0 406 443 1 1
    SCOC DEK 0 0 171 312 1 1
    SCOC ELMO2 0 0 156 157 1 1
    SCOC PRKAR2A 0 0 152 181 1 1
    SCOC SNAP25 0 0 136 235 1 1
    SCOC SMARCD1 0 0 147 251 1 1
    SCOC GDPD1 0 0 0 288 1 1
    SCOC HSPA13 0 0 0 198 1 1
    SCOC HSPA2 0 0 0 167 1 1
    SCOC EPB41L2 0 0 0 246 1 1
    SCOC CCDC185 0 0 180 179 1 1
    SCOC ANKRD26 0 0 193 316 1 1
    SCOC NDUFS6 0 0 147 185 1 1
    SCOC TMEM167A 0 0 0 293 1 1
    SCOC VPS51 0 0 284 284 1 1
    SCOC ELMOD2 0 0 233 261 1 1
    SCOC RNF113A 0 0 242 262 1 1
    SCOC ACP5 0 0 155 154 1 1
    SCOC AOC1 0 0 0 198 1 1
    SCOC ANKK1 0 0 325 476 1 1
    SCOC KCNT2 0 0 602 768 1 1
    SCOC NAA35 0 0 95 304 1 1
    SCOC MPZL3 0 0 253 252 1 1
    SCOC NXT2 0 0 0 164 1 1
    SCOC AP3S1 0 0 0 277 1 1
    SCOC UNC119B 0 0 0 159 1 1
    SCOC AP4S1 0 0 0 177 1 1
    SCOC U2AF2 0 0 90 229 1 1
    SCOC GOLPH3 0 0 217 217 1 1
    SCOC SYPL1 0 0 228 247 1 1
    SCOC AP2A2 0 0 0 215 1 1
    SCOC ITSN2 0 0 144 288 1 1
    SCOC PCNT 0 0 165 177 1 1
    SCOC RAB3GAP1 0 0 263 341 1 1
    SCOC PIP4K2A 0 0 0 258 1 2
    SCOC FAM89B 0 0 308 640 1 1
    SCOC PRPF38B 0 0 269 668 1 1
    SCOC VGLL4 0 0 156 155 1 1
    SCOC UVRAG 0 0 771 771 1 2
    SCOC ICA1 0 0 0 153 1 1
    SCOC ICA1L 0 0 0 153 1 1
    SCOC EPB41L1 0 0 0 246 1 1
    SCOC KIAA1549L 0 0 361 584 1 1
    SCOC CDC16 0 0 102 230 1 1
    SCOC AP1S2 0 0 0 177 1 1
    SCOC CLGN 0 0 234 250 1 1
    SCOC DLD 0 0 0 213 1 1
    SCOC HSPA1L 0 0 0 167 1 1
    SCOC ARF1 0 0 170 205 1 1
    SCOC ATP5E 0 0 143 196 1 1
    SCOC ARL3 0 0 671 699 1 1
    SCOC C17orf58 0 0 310 309 1 1
    SCOC TAF13 0 0 0 167 1 1
    SCOC PIKFYVE 0 0 0 152 1 1
    SCOC CLUAP1 270 0 0 270 1 1
    SCOC CFP 0 0 174 192 1 1
    SCOC FRMD5 0 0 0 152 1 1
    SCOC PRKRA 0 0 134 316 1 1
    SCOC CADM2 0 0 519 738 1 1
    SCOC ARFIP2 0 0 457 609 1 1
    SCOC EPB41L3 115 0 0 305 1 1
    SCOC FYCO1 0 0 134 188 1 2
    SCOC ELMO3 0 0 180 181 1 1
    SCOC MAPK8IP1 0 0 272 334 1 1
    SCOC TRMT112 272 0 0 272 1 1
    SCOC FEZ2 684 0 465 976 1 1
    SCOC CSMD1 0 0 223 494 1 1
    SCOC KCNAB2 0 0 149 239 1 1
    SCOC PPIE 0 0 273 273 1 1
    SCOC KIF1A 0 0 215 282 1 1
    SCOC PPFIA4 0 0 94 190 1 1
    SCOC BRSK2 0 0 156 155 1 1
    SCOC GABARAPL2 0 0 74 168 1 2
    SCOC SWAP70 0 0 140 274 1 1
    SCOC AGPAT5 0 0 193 193 1 1
    SCOC BFSP2 250 0 0 250 1 1
    SCOC DISC1 0 0 199 199 1 1
    SCOC AGFG2 0 0 260 420 1 1
    SCOC RIIAD1 0 0 323 687 1 1
    SCOC ZNF418 0 0 340 340 1 1
    SCOC AP1S3 0 0 0 177 1 1
    SCOC EPB41 0 0 0 210 1 1
    SCOC NRBF2 129 0 448 499 1 2
    SCOC PQLC1 0 0 394 696 1 1
    SCOC PDLIM3 0 0 139 191 1 1
    SCOC UBA3 0 0 46 199 1 1
    SCOC SKP1 0 0 0 152 1 1
    SCOC ENSG00000263020 0 0 163 163 1 1
    SCOC TIAM1 0 0 146 199 1 1
    SCOC ARFIP1 0 0 212 300 1 1
    SCOC NECAP2 0 0 280 404 1 1
    SCOC KCTD5 0 0 260 296 1 1
    SCOC ARL1 213 600 469 849 1 1
    SCOC INSL4 0 0 211 211 1 1
    SCOC RAB28 0 0 0 158 1 1
    SCOC ARHGAP42 0 0 469 469 1 1
    SCOC HMGN1 0 0 113 215 1 1
    SCOC TBC1D30 179 0 0 179 1 1
    SCOC PIP4K2B 0 0 0 258 1 1
    SCOC HINT3 0 0 0 153 1 1
    SCOC SLC35G1 0 0 455 647 1 1
    SCOC TGOLN2 161 0 0 161 1 1
    SCOC DPY30 0 0 0 321 1 1
    SCOC PSMC6 0 0 0 215 1 1
    SCOC RPGRIP1L 0 0 113 265 1 1
    SCOC RABEP2 0 0 286 291 1 1
    SCOC FEZF2 0 0 364 417 1 1
    SCOC GRIP1 0 0 303 303 1 1
    SCOC PDGFRL 0 0 156 386 1 1
    SCOC TTC12 0 0 459 673 1 1
    SCOC CGNL1 0 0 56 164 1 1
    SCOC PQLC2 0 0 0 189 1 1
    SCOC HSPA12A 0 0 0 267 1 1
    SCOC SUOX 0 0 0 307 1 1
    SCOC ROBO2 0 0 293 354 1 1
    SCOC KCNMA1 0 0 211 296 1 1
    SCOC PPFIA2 0 0 236 405 1 1
    SCOC UBXN11 0 0 234 234 1 1
    SCOC MRPL1 0 0 0 162 1 1
    SCOC ABLIM1 0 0 170 245 1 1
    SCOC CADM1 0 0 0 368 1 1
    SCOC MORC1 0 0 208 208 1 1
    SCOC CBX3 0 0 107 150 1 1
    SCOC NSMF 0 0 74 235 1 1
    SCOC ENAH 0 0 163 220 1 1
    SCOC C2orf80 0 0 601 601 1 1
    SCOC PIK3C3 0 0 150 171 1 2
    SCOC CHMP2B 0 0 0 154 1 2
    SCOC AKAP9 0 0 207 207 1 1
    SCOC GOLGA1 0 0 325 392 1 1
    SCOC FEZF1 0 0 414 463 1 1
    SCOC RNF150 0 0 233 243 1 1
    SCOC IGDCC3 0 0 204 238 1 1
    SCOC PIP5K1B 0 0 0 175 1 1
    SCOC ROBO1 0 0 279 342 1 1
    SCOC INPP4B 0 0 205 205 1 1
    SCOC ATG16L1 183 0 71 208 1 2
    SCOC QRFP 0 0 184 183 1 1
    SCOC STX1A 0 0 155 162 1 1
    SCOC UNC119 0 0 467 533 1 1
    SCOC ZYG11B 0 0 420 471 1 1
    SCOC CMTM1 0 0 282 289 1 1
    SCOC EBAG9 0 0 0 150 1 1
    SCOC RAB24 0 0 185 207 1 2
    SCOC HNRNPH1 272 0 0 306 1 1
    SCOC HSPA8 0 0 0 167 1 2
    SCOC CASP4 0 0 208 208 1 2
    SCOC TLK2 0 0 173 204 1 1
    SCOC SYS1 0 0 150 238 1 1
    SCOC SLC30A9 0 0 0 151 1 1
    SCOC OLFM1 0 0 150 296 1 1
    SCOC TNNI2 0 0 125 159 1 1
    SCOC KCNT1 0 0 50 210 1 1
    SCOC ZNF704 0 0 309 321 1 1
    SCOC AP1G1 0 0 0 157 1 1
    SCOC PDE4DIP 0 0 180 563 1 1
    SCOC TBC1D9 0 0 218 218 1 1
    SCOC HSPA1B 0 0 0 167 1 1
    SCOC ATG4D 0 0 123 158 1 2
    SCOC GOLGB1 0 0 158 177 1 1
    SCOC DHX15 0 0 113 298 1 1
    SCOC DOK5 170 0 0 169 1 1
    SCOC ZNF330 0 0 500 518 1 1
    SCOC LHPP 0 0 218 239 1 1
    SCOC MEAF6 0 0 175 261 1 1
    SCOC ULK2 0 0 141 224 1 2
    SCOC HSPA1A 0 0 0 167 1 1
    SCOC SUFU 0 0 107 158 1 1
    SCOC SCO1 0 0 155 154 1 1
    SCOC ARF6 0 0 97 153 1 1
    SCOC AP1S1 0 0 0 177 1 1
    SCOC SLC36A3 0 0 204 221 1 1
    SCOC BECN1 0 0 166 165 1 2
    SCOC DRAP1 0 0 223 433 1 1
    SCOC DNAJC13 0 0 150 334 1 1
    SCOC FRMD3 0 0 0 152 1 1
    SCOC TBC1D25 0 0 224 245 1 1
    SCOC FTH1 0 0 75 217 1 1
    SCOC RPS21 0 0 54 154 1 1
    SCOC JAKMIP3 0 0 284 336 1 1
    SCOC AP3S2 0 0 0 277 1 1
    SCOC RGPD8 0 0 235 235 1 1
    SCOC DTX4 0 0 166 197 1 1
    SCOC ROMO1 0 0 171 171 1 1
    SCOC CASQ1 0 0 124 176 1 1
    SCOC POLR2M 0 0 155 154 1 1
    SCOC PIP5K1A 0 0 0 175 1 1
    SCOC VBP1 0 0 0 150 1 1
    SCOC CALML4 0 0 261 261 1 1
    SCOC KIAA2022 0 0 218 353 1 1
    SCOC PSKH1 0 0 134 156 1 1
    SCOC ARL13B 0 0 0 260 1 1
    SCOC GDPD3 0 0 231 518 1 1
    SCOC ENY2 0 0 0 256 1 1
    SCOC SCHIP1 379 0 0 379 1 1
    SCOC HS1BP3 0 0 269 343 1 2
    SCOC HSPA6 0 0 0 167 1 1
    SCOC C15orf38-AP3S2 0 0 0 258 1 1
    SCOC MAP1LC3B 161 0 102 267 1 2
    SCOC GCC1 129 0 262 329 1 1
    SCOC NCAM1 0 0 181 181 1 1
    SCOC ULK1 0 0 293 361 1 2
    SCOC DACH1 186 0 0 186 1 1
    SCOC MAP7D2 0 0 283 456 1 1
    SCOC PIP4K2C 0 0 0 369 1 1
    SCOC CARKD 0 0 151 150 1 1
    SCOC RAB6A 0 0 112 150 1 1
    SCOC AP2S1 0 0 0 190 1 1
    SCOC NXT1 0 0 0 164 1 1
    SCOC KRTDAP 0 0 212 212 1 1
    SCOC RMDN2 0 0 122 213 1 1
    SCOC ARFRP1 0 0 337 687 1 1
    SCOC GCC2 0 0 241 321 1 1
    SCOC ACBD3 0 0 108 156 1 1
    SCOC GORAB 0 0 294 379 1 1
    SCOC PSMC5 270 0 0 270 1 1
    SCOC FNBP1 0 0 181 190 1 1
    SCOC GULP1 0 0 125 159 1 1
    SCOC CYTH1 0 0 141 370 1 1
    SCOC EPB41L4A 0 0 0 152 1 1
    SCOC ATP6V1D 0 0 167 578 1 1
    SCOC TBC1D23 0 0 260 338 1 1
    SCOC BICD2 0 0 155 167 1 1
    SCOC SPINK2 0 0 212 514 1 1
    SCOC EPB41L5 0 0 0 152 1 1
    SCOC NECAP1 0 0 0 207 1 1
    SCOC FBXO33 0 0 263 386 1 1
    SCOC GIT1 0 0 96 171 1 1
    SCOC PCCB 0 0 163 197 1 1
    SCOC AP4E1 0 0 0 157 1 1
    SCOC CUL1 0 0 162 265 1 1
    SCOC ARL2 0 0 184 183 1 1
    SCOC NUTF2 0 0 0 188 1 1
    SCOC SEC22C 0 0 322 370 1 1
    SCOC GABARAP 0 0 113 193 1 2
    SCOC RABEP1 0 0 125 278 1 1
    SCOC MGAT4D 0 0 595 595 1 1
    SCOC FEZ1 458 0 876 959 1 1
    SCOC PPP2R1B 0 0 125 176 1 1
    SCOC KIF16B 0 0 195 330 1 1
    SCOC GBA2 0 0 0 157 1 1
    SCOC GOLGA4 0 0 473 494 1 1
    SCOC EPB41L4B 0 0 0 152 1 1
    SCOC PIP5K1C 0 0 0 175 1 1
    SCOC TARBP2 0 0 0 242 1 1
    SCOC GOPC 0 0 138 179 1 2
    SCOC AP2A1 0 0 164 341 1 1
    SCOC ENSG00000272822 0 0 161 186 1 1
    SCOC LRRFIP2 0 0 181 256 1 1
    SCOC C21orf91 360 0 0 360 1 1
    SCOC TPM4 0 0 96 161 1 1
    SCOC RMDN1 0 0 156 179 1 1
    SCOC WAC 0 0 248 254 1 1
    SCOC TWF1 0 0 0 165 1 1
    SCOC RAB3GAP2 0 0 246 262 1 1
    SCOC ANKDD1A 0 0 320 319 1 1
    SCOC HSPA14 0 0 0 167 1 1
    SCOC EPHA6 0 0 323 337 1 1
    SCOC ARSJ 0 0 184 183 1 1
    SCOC SYBU 0 0 183 183 1 1
    SCOC ANKFN1 0 0 270 435 1 1
    SCOC PREX1 0 0 108 198 1 1
    SCOC ATG7 0 0 125 162 1 2
    SCOC GMNN 0 0 150 236 1 1
    SCOC ATG16L2 0 0 155 186 1 2
    SCOC NUP35 0 0 180 240 1 1
    SCOC ZFPL1 0 0 282 317 1 1
    SCOC MATR3 0 0 108 236 1 1
    SCOC DRD2 0 0 142 286 1 1
    SCOC PSMB7 0 0 134 152 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0016239 Biological Process positive regulation of macroautophagy involved_in IDA
    GO:0061635 Biological Process regulation of protein complex stability involved_in IMP
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0000139 Cellular Component Golgi membrane located_in IEA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005768 Cellular Component endosome colocalizes_with IDA
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0005802 Cellular Component trans-Golgi network colocalizes_with IBA
    GO:0005802 Cellular Component trans-Golgi network colocalizes_with IDA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_032547 3 mRNA transcript variant 4 NC_000004 Reference
    NM_001153446 1 mRNA transcript variant 6 NC_000004 Reference
    NM_001153635 1 mRNA transcript variant 7 NC_000004 Reference
    XM_047416067 1 mRNA transcript variant X1 NC_000004 Reference
    XM_047416068 1 mRNA transcript variant X2 NC_000004 Reference
    NM_001153585 1 mRNA transcript variant 5 NC_000004 Reference
    NM_001153690 1 mRNA transcript variant 8 NC_000004 Reference
    NM_001153663 1 mRNA transcript variant 2 NC_000004 Reference
    NM_001153484 2 mRNA transcript variant 1 NC_000004 Reference
    NM_001153552 2 mRNA transcript variant 3 NC_000004 Reference