RHEB

Ras homolog, mTORC1 binding
General Information
Name Ras homolog, mTORC1 binding
Alias
  • GTP-binding protein Rheb
  • Ras homolog enriched in brain 2
Synonyms RHEB2
Gene_family RAS type GTPase family
organism Homo sapiens
entrez_id 6009
location 7q36.1
transcript_count 4
exon_count 11
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]
      Stringdb GTP-binding protein Rheb; Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity; RAS type GTPase family
      nextProt Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    RHEB BioGRID YOD1 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID CDC123 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID SQSTM1 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID ASH2L GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID RPA2 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID RPA1 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID PJA2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID SPPL3 GeneID BioGRID Positive Genetic
    RHEB BioGRID RAF1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RHEB BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID TIPARP GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID PLEKHM1 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID Cavin3 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NUDT9 GeneID BioGRID Co-fractionation
    RHEB BioGRID LAP3 GeneID BioGRID Co-fractionation
    RHEB BioGRID VASP GeneID BioGRID Co-fractionation
    RHEB BioGRID TRIM5 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID PARP1 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID MYC GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RIT1 GeneID BioGRID Negative Genetic
    RHEB BioGRID KRAS GeneID BioGRID Negative Genetic
    RHEB BioGRID EGFR GeneID BioGRID Negative Genetic
    RHEB BioGRID RHOF GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID MAP1LC3B GeneID BioGRID Proximity Label-MS
    RHEB BioGRID M GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID SPATA19 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID CCT8L2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NFATC2IP GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID LMNB2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NAA40 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID VASH2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID SRPRB GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID GNG2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID IL20RA GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID STMN3 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID GPR182 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID UBB GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID TNF GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID TGM3 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID FSCN1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RHEB BioGRID RAC1 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID PDGFRA GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NEDD9 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID ENTPD2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID ALPI GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RPTOR GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
    RHEB BioGRID ATXN3 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RHEB BioGRID MTOR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RHEB BioGRID SLC5A5 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NR3C1 GeneID BioGRID Proximity Label-MS
    RHEB BioGRID MKRN2 GeneID BioGRID Affinity Capture-RNA
    RHEB BioGRID ORF3a GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID MKI67 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
    RHEB BioGRID TRIM63 GeneID BioGRID Two-hybrid
    RHEB BioGRID TRIM55 GeneID BioGRID Two-hybrid
    RHEB BioGRID APPBP2 GeneID BioGRID Two-hybrid
    RHEB BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RNF152 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RHEB BioGRID USP4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RHEB BioGRID TSC2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RHEB BioGRID TSC1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RHEB BioGRID MECOM GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID NR2C2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID PHB1 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
    RHEB BioGRID HTT GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RHEB BioGRID ENPP7 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RELL2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID DUSP19 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID TMEM52B GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID SLC15A1 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID LGALS7 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID LAMP2 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID CREB3 GeneID BioGRID Two-hybrid
    RHEB BioGRID LDHB GeneID BioGRID Co-fractionation
    RHEB BioGRID ITGB8 GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RAB7A GeneID BioGRID Co-fractionation; Co-localization
    RHEB BioGRID VPS4A GeneID BioGRID Affinity Capture-MS
    RHEB BioGRID RPS6KB1 GeneID BioGRID Biochemical Activity
    RHEB BioGRID PLD1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RHEB BioGRID FKBP8 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RHEB BioGRID Appl1 GeneID BioGRID Two-hybrid
    RHEB BioGRID Blzf1 GeneID BioGRID Two-hybrid
    RHEB BioGRID Traf2 GeneID BioGRID Two-hybrid
    RHEB BioGRID ARIH2 GeneID BioGRID Two-hybrid
    RHEB BioGRID TRAF2 GeneID BioGRID Affinity Capture-Western
    RHEB BioGRID NCAM1 GeneID BioGRID Two-hybrid
    RHEB BioGRID RABAC1 GeneID BioGRID Two-hybrid
    RHEB BioGRID BNIP3L GeneID BioGRID Two-hybrid
    RHEB BioGRID BNIP3 GeneID BioGRID FRET; Two-hybrid
    RHEB BioGRID ECSIT GeneID BioGRID Two-hybrid
    RHEB BioGRID PSEN2 GeneID BioGRID Two-hybrid
    RHEB BioGRID PSEN1 GeneID BioGRID Two-hybrid
    RHEB BioGRID APOE GeneID BioGRID Two-hybrid
    RHEB BioGRID A2M GeneID BioGRID Two-hybrid
    RHEB Protein ATR GeneID HPRD None
    RHEB Protein ATM GeneID HPRD None
    RHEB Protein RPTOR GeneID HPRD None
    RHEB Protein PDE6D GeneID HPRD None
    RHEB Protein MTOR GeneID HPRD None
    RHEB Protein TSC2 GeneID HPRD None
    RHEB Protein RAF1 GeneID HPRD None
    RHEB Protein BRAF GeneID HPRD None
    RHEB BioGRID RAB9A GeneID BioGRID Co-localization
    RHEB BioGRID RAP1A GeneID BioGRID Affinity Capture-Western
    RHEB BioGRID PDE6D GeneID BioGRID Two-hybrid
    RHEB BioGRID HRAS GeneID BioGRID Affinity Capture-Western
    RHEB BioGRID ATR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RHEB BioGRID ATM GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RHEB Protein MTOR GeneID BIND FRAP1 (mTOR) interacts with Rheb.
    RHEB Protein RPTOR GeneID BIND Raptor interacts with Rheb.
    RHEB Protein RAF1 GeneID BIND RAF interacts with Rheb.
    RHEB Protein MLST8 GeneID BIND GBL (LST8) interacts with Rheb.
    RHEB Protein TSC2 GeneID BIND TSC2 interacts with Rheb.
    RHEB Protein ATR GeneID BIND ATR interacts with Rheb.
    RHEB Protein ATM GeneID BIND ATM interacts with Rheb.
    RHEB Protein None None BIND RHEB interacts with GTP.
    RHEB Protein None None BIND RHEB interacts with GDP.
    RHEB Protein BCL2 GeneID BIND Bcl-2 interacts with Rheb.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    RHEB LAMTOR2 0 600 467 818 1 1
    RHEB FKBP1C 0 0 90 348 1 1
    RHEB RALGAPB 0 0 212 212 1 1
    RHEB TXNIP 0 0 113 153 1 1
    RHEB CSNK2A1 0 0 107 159 1 1
    RHEB ZMPSTE24 0 0 134 206 1 1
    RHEB DRAM1 0 0 283 282 1 2
    RHEB NPR3 0 0 0 169 1 1
    RHEB RAB7A 499 0 459 659 1 2
    RHEB ATP12A 0 0 218 249 1 1
    RHEB PIK3C2G 0 0 149 267 1 1
    RHEB GCG 0 0 202 344 1 1
    RHEB DOCK6 0 0 0 174 1 1
    RHEB TCP1 0 0 46 208 1 1
    RHEB RND3 0 0 138 182 1 1
    RHEB ATG4B 0 0 166 277 1 2
    RHEB AP2A2 0 0 0 197 1 1
    RHEB RHOF 0 0 88 171 1 1
    RHEB CCND2 0 0 141 208 1 1
    RHEB RPS6KA2 0 0 469 603 1 1
    RHEB MAP4K1 0 0 0 189 1 1
    RHEB SDCBP 0 0 864 872 1 1
    RHEB MAP3K14 0 0 0 262 1 1
    RHEB RAB23 0 0 98 194 1 2
    RHEB ZNF805 0 0 156 177 1 1
    RHEB GLTSCR2 0 0 0 169 1 1
    RHEB UVRAG 0 0 425 524 1 2
    RHEB PPP2R2B 0 0 0 207 1 1
    RHEB ATF3 0 0 71 275 1 1
    RHEB PARD6A 0 0 0 173 1 1
    RHEB RTKN 0 0 55 150 1 1
    RHEB RAB1B 0 0 157 274 1 2
    RHEB ENSG00000248751 0 0 0 156 1 1
    RHEB ADCY6 0 0 48 178 1 1
    RHEB PIK3R2 0 0 340 385 1 1
    RHEB ITK 0 0 70 166 1 1
    RHEB C22orf29 0 0 193 193 1 1
    RHEB VPS11 0 0 48 240 1 2
    RHEB LARS 0 0 493 581 1 1
    RHEB NBR1 0 0 284 298 1 2
    RHEB DNAJC6 0 0 0 207 1 1
    RHEB STK32C 0 0 0 191 1 1
    RHEB TNF 273 0 253 433 1 1
    RHEB FNIP2 0 0 391 420 1 1
    RHEB EEF2 0 0 459 572 1 1
    RHEB SLC2A4RG 0 0 0 163 1 1
    RHEB ADCY7 0 0 0 172 1 1
    RHEB GOLGA7 0 0 113 186 1 1
    RHEB PPP1R15A 0 0 166 202 1 2
    RHEB UNC119B 0 0 109 270 1 1
    RHEB CDK3 0 0 0 349 1 1
    RHEB FMR1 0 0 265 336 1 1
    RHEB MAP4K2 0 0 49 195 1 1
    RHEB SLC7A11 0 0 140 192 1 1
    RHEB MYO18B 0 0 0 163 1 1
    RHEB ATXN2L 0 0 51 216 1 1
    RHEB DIAPH3 0 0 0 160 1 1
    RHEB WIPI2 0 0 218 282 1 2
    RHEB PNPLA6 0 0 0 161 1 1
    RHEB ALDH7A1 0 0 120 160 1 1
    RHEB UBL3 0 0 0 160 1 1
    RHEB FIS1 0 0 157 256 1 2
    RHEB EEF1E1 0 0 0 196 1 1
    RHEB FOXA2 0 0 73 330 1 1
    RHEB DOCK5 0 0 0 174 1 1
    RHEB AARS 0 0 44 155 1 1
    RHEB SSH3 0 0 0 160 1 1
    RHEB RNASEL 0 0 0 181 1 1
    RHEB HPRT1 0 0 82 173 1 1
    RHEB ITSN1 0 0 54 233 1 1
    RHEB BCAT2 0 0 261 302 1 1
    RHEB ARHGAP6 0 0 0 198 1 1
    RHEB UXS1 0 0 0 159 1 1
    RHEB DDIT4 0 0 662 669 1 1
    RHEB RRAS2 0 0 284 160 1 1
    RHEB CTLA4 0 0 212 212 1 1
    RHEB ARHGAP5 0 0 0 156 1 1
    RHEB LIN28A 0 0 0 150 1 1
    RHEB SZT2 0 900 295 926 1 1
    RHEB DUSP6 0 0 90 182 1 1
    RHEB PDPK1 0 0 509 740 1 2
    RHEB PLCH1 0 0 0 194 1 1
    RHEB RAB3IP 0 0 714 752 1 1
    RHEB CAT 0 0 216 242 1 1
    RHEB WNT10B 0 0 95 172 1 1
    RHEB ARHGEF25 0 0 0 160 1 1
    RHEB AP2B1 0 0 0 207 1 1
    RHEB EPN3 0 0 0 237 1 1
    RHEB GUCY2F 0 0 0 169 1 1
    RHEB NPR2 0 0 0 169 1 1
    RHEB MAGI2 0 0 57 154 1 1
    RHEB CDIPT 0 0 0 184 1 1
    RHEB STXBP3 0 0 0 226 1 1
    RHEB GRIA1 0 0 181 194 1 1
    RHEB CCT6A 0 0 0 275 1 1
    RHEB ABR 0 0 0 173 1 1
    RHEB ZFYVE9 0 0 293 293 1 1
    RHEB RASA1 0 0 202 266 1 1
    RHEB EPHB1 0 0 0 172 1 1
    RHEB RALGPS2 0 0 0 175 1 1
    RHEB SGK1 0 0 587 769 1 1
    RHEB IRS1 0 0 606 722 1 1
    RHEB NTRK1 0 0 195 278 1 1
    RHEB SESN1 0 900 456 957 1 2
    RHEB PGR 0 0 128 224 1 1
    RHEB CDK1 0 0 181 392 1 1
    RHEB REM1 0 0 66 169 1 1
    RHEB MYO6 0 0 0 154 1 1
    RHEB RPS6KB1 270 900 805 994 1 2
    RHEB EPHA1 0 0 61 157 1 1
    RHEB MICAL3 0 0 0 163 1 1
    RHEB ULK3 0 0 69 448 1 2
    RHEB ALDOC 0 0 0 156 1 1
    RHEB SREBF2 0 0 210 352 1 1
    RHEB ARAP1 0 0 0 158 1 1
    RHEB RAB44 0 0 0 191 1 1
    RHEB ATR 270 0 92 550 1 1
    RHEB HK3 0 0 0 162 1 1
    RHEB WNT8B 0 0 70 164 1 1
    RHEB PRPF19 0 0 0 191 1 1
    RHEB PDLIM7 0 0 46 152 1 1
    RHEB RGL3 0 0 141 317 1 1
    RHEB MYO18A 0 0 142 266 1 1
    RHEB EPHB3 0 0 61 189 1 1
    RHEB IRS4 0 0 182 196 1 1
    RHEB DOCK2 0 0 0 174 1 1
    RHEB SLK 0 0 209 231 1 1
    RHEB ATG4C 0 0 201 301 1 2
    RHEB SMURF2 0 0 57 152 1 1
    RHEB TUBA1C 0 0 0 186 1 1
    RHEB RASGEF1B 0 0 0 175 1 1
    RHEB STAMBP 0 0 0 162 1 1
    RHEB RAB25 0 0 74 182 1 2
    RHEB SRC 0 0 384 465 1 1
    RHEB EED 0 0 0 201 1 1
    RHEB DUSP19 83 0 0 170 1 1
    RHEB SPRED1 0 0 54 193 1 1
    RHEB YWHAB 0 600 306 783 1 1
    RHEB KIF5B 0 0 107 169 1 1
    RHEB EEA1 0 0 160 209 1 1
    RHEB RAB11FIP2 0 0 67 174 1 1
    RHEB HSD17B8 0 0 0 177 1 1
    RHEB CRIP2 0 0 0 160 1 1
    RHEB RAPGEF6 0 0 99 203 1 1
    RHEB YIPF4 0 0 0 160 1 1
    RHEB TUBB8B 0 0 0 155 1 1
    RHEB STAT6 0 0 171 184 1 1
    RHEB ACLY 0 0 253 291 1 1
    RHEB LRPAP1 0 0 324 329 1 1
    RHEB ENAH 0 0 0 182 1 1
    RHEB TEN1-CDK3 0 0 0 349 1 1
    RHEB EIF2AK3 0 0 265 265 1 2
    RHEB FLT1 0 0 75 169 1 1
    RHEB VHL 0 0 150 193 1 1
    RHEB IQGAP3 0 0 0 235 1 1
    RHEB MVD 0 0 0 166 1 1
    RHEB DNMBP 0 0 0 258 1 1
    RHEB TUBB8 0 0 0 191 1 1
    RHEB RABGEF1 0 0 66 153 1 1
    RHEB PKD1 0 0 309 309 1 1
    RHEB CRYBB2 0 0 0 190 1 1
    RHEB MITF 0 0 157 338 1 1
    RHEB RRAGA 0 600 810 967 1 2
    RHEB JAK1 0 0 140 310 1 1
    RHEB EIF2S1 0 0 334 462 1 2
    RHEB LDHB 272 0 0 283 1 1
    RHEB NTN1 0 0 108 163 1 1
    RHEB TOMM20 0 0 124 177 1 1
    RHEB STX17 0 0 161 268 1 2
    RHEB LIN28B 0 0 0 150 1 1
    RHEB RHOH 0 0 107 218 1 1
    RHEB PDE9A 0 0 0 175 1 1
    RHEB TCHP 0 0 296 296 1 1
    RHEB SEC13 0 900 370 960 1 1
    RHEB TRAPPC6B 0 0 0 153 1 1
    RHEB LRRK1 0 0 0 222 1 1
    RHEB AP1S3 0 0 0 156 1 1
    RHEB GLTP 0 0 0 213 1 1
    RHEB STK3 0 0 49 215 1 1
    RHEB FKBP6 0 0 0 227 1 1
    RHEB CDKN1B 0 0 365 388 1 2
    RHEB BOLA2-SMG1P6 0 0 0 160 1 1
    RHEB ZFYVE1 0 0 185 203 1 2
    RHEB FKBPL 0 0 0 184 1 1
    RHEB OXSM 0 0 0 236 1 1
    RHEB ECI2 0 0 0 158 1 1
    RHEB TRRAP 0 0 184 285 1 1
    RHEB ARHGAP15 0 0 0 159 1 1
    RHEB RAB28 0 0 0 267 1 1
    RHEB TSC2 871 900 989 999 1 2
    RHEB ABCD3 0 0 143 197 1 1
    RHEB RABIF 0 0 0 342 1 1
    RHEB BNIP3L 192 0 983 986 1 2
    RHEB GNAL 0 0 0 195 1 1
    RHEB AGAP4 0 0 0 154 1 1
    RHEB CD4 0 0 261 294 1 1
    RHEB RAB40C 0 0 0 221 1 1
    RHEB ATF4 0 0 263 347 1 2
    RHEB MDP1 0 0 0 193 1 1
    RHEB FOXA1 0 0 54 316 1 1
    RHEB SGK3 0 0 223 574 1 1
    RHEB TUBA3C 0 0 0 159 1 1
    RHEB MKI67 270 0 0 315 1 1
    RHEB GPN1 0 0 0 205 1 1
    RHEB C17orf59 0 0 150 175 1 1
    RHEB CDC42BPA 0 0 89 183 1 1
    RHEB PPARG 0 0 285 364 1 1
    RHEB SLIT2 0 0 49 181 1 1
    RHEB UBE3A 0 0 155 199 1 1
    RHEB AKT1 0 900 881 993 1 2
    RHEB CYTH4 0 0 0 154 1 1
    RHEB PTP4A3 0 0 126 465 1 1
    RHEB XIAP 0 0 150 186 1 1
    RHEB PPP2R4 0 0 370 396 1 1
    RHEB ARHGEF26 0 0 57 174 1 1
    RHEB AVL9 0 0 0 178 1 1
    RHEB ATF6 0 0 270 301 1 2
    RHEB ACE2 0 0 0 161 1 1
    RHEB IKBKB 0 0 284 411 1 1
    RHEB GDI2 0 0 81 246 1 1
    RHEB SLC36A1 0 0 307 333 1 1
    RHEB FGFR1 0 0 149 203 1 1
    RHEB RHOC 0 0 195 259 1 1
    RHEB PIKFYVE 0 0 235 345 1 1
    RHEB SEH1L 0 900 391 961 1 1
    RHEB AP1S2 0 0 0 156 1 1
    RHEB SIRT4 0 0 247 246 1 1
    RHEB GSK3A 0 0 95 339 1 1
    RHEB SLC7A2 0 0 44 156 1 1
    RHEB CDC16 0 0 266 305 1 1
    RHEB WWOX 0 0 0 176 1 1
    RHEB ARFIP2 0 0 0 150 1 1
    RHEB FOXF2 0 0 0 160 1 1
    RHEB NKX2-8 0 0 147 203 1 1
    RHEB ERBB2 0 0 400 488 1 2
    RHEB PKD2 0 0 184 183 1 1
    RHEB CDK15 0 0 0 269 1 1
    RHEB ATP6V1A 0 600 99 703 1 1
    RHEB MAP3K1 0 0 0 262 1 1
    RHEB SLIT3 0 0 60 154 1 1
    RHEB CCNE2 0 0 45 192 1 1
    RHEB KIAA1614 0 0 0 173 1 1
    RHEB AP3S2 0 0 0 156 1 1
    RHEB RAB19 0 0 0 226 1 1
    RHEB RABAC1 192 0 147 359 1 1
    RHEB MLST8 800 900 861 998 1 2
    RHEB TBC1D25 0 0 0 156 1 1
    RHEB ENSG00000280433 0 0 0 171 1 1
    RHEB KRAS 0 0 391 203 1 1
    RHEB PKN2 0 0 46 207 1 1
    RHEB CORO1C 0 0 0 164 1 1
    RHEB TSSK4 0 0 0 154 1 1
    RHEB RND2 0 0 113 179 1 1
    RHEB GNB3 0 0 0 170 1 1
    RHEB PRKAR1A 0 0 81 283 1 2
    RHEB WDR59 0 900 417 973 1 1
    RHEB RHOD 0 0 142 231 1 1
    RHEB SOCS3 0 0 150 165 1 1
    RHEB GAS7 0 0 0 163 1 1
    RHEB RXRA 0 0 66 169 1 1
    RHEB TCEB1 0 0 0 156 1 1
    RHEB STAT5A 0 0 144 176 1 1
    RHEB ENSG00000268861 0 0 0 160 1 1
    RHEB TMEM11 0 0 431 443 1 1
    RHEB MYO1C 0 0 63 187 1 1
    RHEB DEPTOR 0 900 710 972 1 1
    RHEB TUBG2 0 0 0 155 1 1
    RHEB PAK4 0 0 60 244 1 1
    RHEB CCT6B 0 0 0 174 1 1
    RHEB RHOBTB3 0 0 0 168 1 1
    RHEB LPIN1 0 0 341 398 1 2
    RHEB CARD11 0 0 108 168 1 1
    RHEB BECN1 0 0 529 676 1 2
    RHEB MAPT 0 0 150 199 1 2
    RHEB AP1S1 0 0 0 196 1 1
    RHEB EEF1G 0 0 0 222 1 1
    RHEB IL2 0 0 180 240 1 1
    RHEB GIT2 0 0 0 236 1 1
    RHEB FGD1 0 0 0 160 1 1
    RHEB RPL23A 0 0 45 170 1 1
    RHEB FLT4 0 0 82 194 1 1
    RHEB MAPK11 0 0 151 334 1 1
    RHEB DUSP1 0 0 86 173 1 1
    RHEB PPM1A 0 0 51 163 1 1
    RHEB CAD 0 0 460 481 1 1
    RHEB ELAVL4 0 0 240 247 1 1
    RHEB ACE 0 0 82 196 1 1
    RHEB STX16 0 0 0 245 1 1
    RHEB COG7 0 0 0 171 1 1
    RHEB SLC1A1 0 0 48 256 1 1
    RHEB RASGRF1 0 0 52 185 1 1
    RHEB DLG3 0 0 84 162 1 1
    RHEB CREBRF 0 0 143 182 1 1
    RHEB PRR5L 0 0 236 243 1 1
    RHEB ENSG00000268643 0 0 0 273 1 1
    RHEB GPR137B 0 0 64 162 1 1
    RHEB MAPK15 0 0 66 222 1 2
    RHEB EGLN1 0 0 119 167 1 1
    RHEB PSMG1 0 0 48 259 1 1
    RHEB PLD2 0 0 265 504 1 1
    RHEB RNF152 270 0 211 414 1 1
    RHEB ATG101 0 600 383 764 1 2
    RHEB ELF3 0 0 60 154 1 1
    RHEB EIF4B 0 0 504 585 1 1
    RHEB TUBB6 0 0 0 155 1 1
    RHEB LMO7 0 0 0 154 1 1
    RHEB TBC1D3D 0 0 65 177 1 1
    RHEB PTGS2 0 0 123 155 1 1
    RHEB TUBB2B 0 0 0 167 1 1
    RHEB SMURF1 0 0 67 161 1 1
    RHEB ERBB3 0 0 193 311 1 1
    RHEB CASP3 0 0 324 356 1 2
    RHEB PDIA6 0 0 108 157 1 1
    RHEB RASGRP4 0 0 0 183 1 1
    RHEB CNKSR3 0 0 0 155 1 1
    RHEB YIF1B 0 0 0 238 1 1
    RHEB TBC1D7 0 800 793 959 1 2
    RHEB CEBPB 0 0 183 197 1 1
    RHEB RASA2 0 0 0 560 1 1
    RHEB ATG16L1 0 0 368 396 1 2
    RHEB INPP4B 0 0 215 215 1 1
    RHEB PIK3CD 0 0 370 535 1 1
    RHEB CNKSR2 0 0 0 155 1 1
    RHEB WNT3 0 0 74 168 1 1
    RHEB RIPK1 0 0 92 188 1 1
    RHEB TUBA8 0 0 0 159 1 1
    RHEB CNOT3 0 0 0 159 1 1
    RHEB CDKN2A 0 0 299 324 1 2
    RHEB FGD3 0 0 0 160 1 1
    RHEB PPP6C 0 0 84 470 1 1
    RHEB RPS27A 131 0 0 164 1 1
    RHEB TBC1D29 0 0 0 156 1 1
    RHEB TUBG1 0 0 62 173 1 1
    RHEB TBC1D3F 0 0 0 156 1 1
    RHEB GSK3B 0 0 267 474 1 2
    RHEB GRIN3A 0 0 714 725 1 1
    RHEB ATP6V1E2 0 600 0 620 1 1
    RHEB PLXND1 0 0 0 163 1 1
    RHEB INSRR 0 0 43 385 1 1
    RHEB ARHGAP36 0 0 0 198 1 1
    RHEB PLCZ1 0 0 0 194 1 1
    RHEB PFN1 0 0 0 160 1 1
    RHEB RIN1 0 0 182 407 1 1
    RHEB UNC119 0 0 91 224 1 1
    RHEB EPHB2 0 0 43 174 1 2
    RHEB TTI1 0 0 427 512 1 1
    RHEB RAB41 0 0 0 303 1 1
    RHEB IGF2 0 0 188 188 1 1
    RHEB GUCY2D 0 0 0 169 1 1
    RHEB RAP1GAP 0 0 298 371 1 1
    RHEB COPG2 0 0 0 190 1 1
    RHEB REV3L 0 0 0 162 1 1
    RHEB TEAD1 0 0 90 168 1 1
    RHEB PFN2 0 0 0 153 1 1
    RHEB IL10 0 0 147 165 1 1
    RHEB TBC1D8 0 0 0 174 1 1
    RHEB FGFR4 0 0 95 152 1 1
    RHEB NPM1 0 0 112 183 1 1
    RHEB TIPRL 0 0 150 168 1 1
    RHEB FLT3 0 0 140 194 1 1
    RHEB ARFGEF1 0 0 0 161 1 1
    RHEB DLG4 0 0 201 261 1 1
    RHEB PREX1 0 0 150 361 1 1
    RHEB IPCEF1 0 0 67 254 1 1
    RHEB NR1H4 0 0 58 162 1 1
    RHEB NTRK3 0 0 67 163 1 1
    RHEB RRAGB 0 600 758 956 1 2
    RHEB SLC2A14 0 0 150 205 1 1
    RHEB ACSL4 0 0 0 152 1 1
    RHEB STK40 0 0 0 154 1 1
    RHEB SGSM1 0 0 0 156 1 1
    RHEB EIF4EBP3 0 0 308 321 1 1
    RHEB MASTL 0 0 0 151 1 1
    RHEB DOCK4 0 0 0 207 1 1
    RHEB GNB4 0 0 0 170 1 1
    RHEB DOCK8 0 0 0 174 1 1
    RHEB MARK2 0 0 234 234 1 1
    RHEB FKBP2 0 0 106 268 1 1
    RHEB TSSK6 0 0 0 154 1 1
    RHEB LDHA 0 0 218 230 1 1
    RHEB CHURC1-FNTB 0 0 54 332 1 1
    RHEB AMBRA1 0 0 391 396 1 2
    RHEB NPTX2 0 0 134 153 1 1
    RHEB NFE2L1 0 0 0 235 1 1
    RHEB KIT 0 0 194 245 1 1
    RHEB OPTN 0 0 163 176 1 2
    RHEB CSRP1 0 0 0 155 1 1
    RHEB PDK4 0 0 92 175 1 1
    RHEB HOMER1 0 0 154 190 1 1
    RHEB PIM2 0 0 134 247 1 2
    RHEB ESR1 0 0 248 331 1 1
    RHEB PDE10A 0 0 0 175 1 1
    RHEB ADCY8 0 0 0 172 1 1
    RHEB LMNB1 0 0 160 173 1 1
    RHEB KIF3A 0 0 95 177 1 1
    RHEB UNKL 0 0 88 236 1 1
    RHEB EOMES 0 0 309 319 1 1
    RHEB RAB22A 0 0 92 257 1 1
    RHEB BBS5 0 0 0 168 1 1
    RHEB MCF2 0 0 456 518 1 1
    RHEB YAP1 0 0 155 203 1 1
    RHEB SMEK1 0 0 62 150 1 1
    RHEB AP4E1 0 0 48 202 1 1
    RHEB PDIA5 0 0 171 196 1 1
    RHEB IQSEC1 0 0 0 154 1 1
    RHEB PLCD1 0 0 0 194 1 1
    RHEB ATP4A 0 0 218 248 1 1
    RHEB PLCD3 0 0 0 194 1 1
    RHEB TEX37 0 0 181 205 1 1
    RHEB CALCOCO2 0 0 233 232 1 2
    RHEB RAB15 0 0 0 258 1 1
    RHEB PPT1 0 0 162 222 1 1
    RHEB AGFG1 0 0 151 267 1 1
    RHEB MAP1LC3B 0 0 327 392 1 2
    RHEB PLXNB1 0 0 0 163 1 1
    RHEB GUCY1A2 0 0 0 169 1 1
    RHEB SARS 0 0 0 291 1 1
    RHEB EFNA2 0 0 72 174 1 1
    RHEB VAMP3 0 0 52 156 1 1
    RHEB ESPN 0 0 0 278 1 1
    RHEB MST1R 0 0 45 249 1 1
    RHEB TSG101 0 0 0 267 1 2
    RHEB VAV1 0 0 124 208 1 1
    RHEB TERT 0 0 91 188 1 1
    RHEB YBX3 0 0 0 150 1 1
    RHEB TBC1D8B 0 0 0 174 1 1
    RHEB FN1 0 0 204 204 1 1
    RHEB RARS 0 0 49 151 1 1
    RHEB MUSK 0 0 0 167 1 1
    RHEB QARS 0 0 66 160 1 1
    RHEB PIP4K2C 0 0 76 177 1 1
    RHEB SPRED2 0 0 0 182 1 1
    RHEB ODF1 0 0 0 179 1 1
    RHEB PTP4A1 0 0 47 207 1 1
    RHEB ACVRL1 0 0 94 205 1 1
    RHEB PRKCA 0 0 420 420 1 1
    RHEB CYTH2 0 0 48 160 1 1
    RHEB RIPK4 0 0 0 181 1 1
    RHEB PKN3 0 0 0 203 1 1
    RHEB ULK1 0 600 612 908 1 2
    RHEB STX7 0 0 47 158 1 2
    RHEB GUCY2C 0 0 0 169 1 1
    RHEB PLK3 0 0 0 223 1 1
    RHEB PKN1 0 0 0 203 1 1
    RHEB ARCN1 0 0 0 178 1 1
    RHEB MYCN 0 0 140 166 1 1
    RHEB SMAD4 0 0 150 282 1 1
    RHEB UBA1 0 0 66 154 1 1
    RHEB SH3BGRL 0 0 46 178 1 1
    RHEB EIF5B 0 0 166 175 1 1
    RHEB PARD3 0 0 66 249 1 1
    RHEB NDUFB7 0 0 0 155 1 1
    RHEB SHANK1 0 0 97 305 1 1
    RHEB STXBP6 0 0 92 208 1 1
    RHEB PARK7 0 0 102 207 1 1
    RHEB EFNA5 0 0 700 707 1 1
    RHEB GRK1 0 0 180 179 1 1
    RHEB FHDC1 0 0 0 239 1 1
    RHEB NGDN 0 0 559 574 1 1
    RHEB LARP1 0 0 193 252 1 1
    RHEB MAP2K5 0 0 45 307 1 1
    RHEB MECP2 0 0 143 166 1 1
    RHEB CAB39 0 0 269 336 1 1
    RHEB PAK7 0 0 49 236 1 1
    RHEB NFE2L2 0 0 184 203 1 1
    RHEB EIF2B5 0 0 218 220 1 1
    RHEB PGAM5 0 0 134 175 1 1
    RHEB AKT2 0 0 457 710 1 1
    RHEB PIP4K2A 0 0 0 167 1 2
    RHEB PFKM 0 0 144 156 1 1
    RHEB SMAP1 0 0 0 175 1 1
    RHEB MAP2K1 0 0 374 549 1 1
    RHEB UNK 0 0 101 253 1 1
    RHEB MFF 0 0 134 171 1 1
    RHEB ODC1 0 0 143 165 1 1
    RHEB VASP 0 0 72 208 1 1
    RHEB ARL8B 0 0 134 176 1 1
    RHEB PDK1 0 0 286 351 1 1
    RHEB MYC 0 0 562 570 1 2
    RHEB PFN4 0 0 0 153 1 1
    RHEB STK32B 0 0 0 191 1 1
    RHEB TRAPPC9 0 0 0 190 1 1
    RHEB STEAP3 0 0 525 525 1 1
    RHEB SLC1A6 0 0 0 250 1 1
    RHEB IGF1R 0 0 424 630 1 1
    RHEB ATP6V1G3 0 600 0 609 1 1
    RHEB KALRN 0 0 66 172 1 1
    RHEB PI3 0 0 260 260 1 1
    RHEB RASAL1 0 0 0 337 1 1
    RHEB GLS 0 0 138 161 1 1
    RHEB TRAF2 270 0 66 301 1 1
    RHEB SLC7A1 0 0 108 213 1 1
    RHEB GNAT3 0 0 0 214 1 1
    RHEB AP4M1 0 0 0 195 1 1
    RHEB APPL1 0 0 74 212 1 1
    RHEB FKBP1B 0 0 77 336 1 1
    RHEB AP4S1 0 0 0 162 1 1
    RHEB PPP3CB 0 0 82 172 1 1
    RHEB TUBA3E 0 0 0 159 1 1
    RHEB GNAT2 0 0 0 214 1 1
    RHEB PIK3CA 0 0 468 607 1 2
    RHEB SLC1A4 0 0 57 223 1 1
    RHEB ACACA 0 0 161 175 1 1
    RHEB RGL1 0 0 113 222 1 1
    RHEB MOB4 0 0 0 235 1 1
    RHEB WNT5B 0 0 63 158 1 1
    RHEB SLC7A4 0 0 0 153 1 1
    RHEB COL2A1 0 0 0 153 1 1
    RHEB PAK1 0 0 113 287 1 1
    RHEB FNTA 0 0 433 487 1 1
    RHEB HSCB 0 0 0 161 1 1
    RHEB CAMKK2 0 0 358 398 1 2
    RHEB RALBP1 0 0 81 181 1 1
    RHEB RPGR 0 0 88 156 1 1
    RHEB SGSM3 0 0 0 156 1 1
    RHEB NPRL2 0 900 506 971 1 1
    RHEB NET1 0 0 0 184 1 1
    RHEB ERN1 0 0 257 333 1 2
    RHEB LAMTOR4 0 600 517 814 1 1
    RHEB PLEKHG5 0 0 0 171 1 1
    RHEB NR2F1 0 0 55 159 1 1
    RHEB NF2 0 0 260 339 1 1
    RHEB OCRL 0 0 59 170 1 1
    RHEB ELAVL2 0 0 234 241 1 1
    RHEB GATA3 0 0 193 262 1 1
    RHEB CDK14 0 0 0 269 1 1
    RHEB HMHA1 0 0 0 174 1 1
    RHEB ATP6V0D1 0 600 0 698 1 1
    RHEB STAT3 0 0 334 345 1 2
    RHEB RAB9A 273 0 0 392 1 2
    RHEB GART 0 0 0 248 1 1
    RHEB TUBA4A 0 0 0 172 1 1
    RHEB PRKCI 0 0 59 212 1 1
    RHEB IRF9 0 0 0 189 1 1
    RHEB CCDC186 0 0 0 163 1 1
    RHEB PLEKHG7 0 0 0 160 1 1
    RHEB PRKCE 0 0 46 207 1 1
    RHEB AP3D1 0 0 0 208 1 1
    RHEB COPB2 0 0 0 213 1 1
    RHEB IL20RA 265 0 0 265 1 1
    RHEB ATP6V0C 0 600 45 615 1 2
    RHEB DCUN1D1 0 0 142 191 1 1
    RHEB VPS53 0 0 0 205 1 1
    RHEB TOR1A 0 0 0 202 1 1
    RHEB MYD88 0 0 138 189 1 1
    RHEB METAP2 0 0 134 249 1 1
    RHEB CCS 0 0 0 157 1 1
    RHEB CDK4 0 0 251 347 1 1
    RHEB SLC2A2 0 0 95 154 1 1
    RHEB LMNA 0 0 167 180 1 1
    RHEB RAB3IL1 0 0 0 168 1 1
    RHEB TXK 0 0 83 177 1 1
    RHEB HK2 0 0 294 383 1 1
    RHEB NGEF 0 0 81 195 1 1
    RHEB KLHDC2 0 0 0 176 1 1
    RHEB LPP 0 0 0 165 1 1
    RHEB DDIT3 0 0 181 195 1 2
    RHEB PRKX 0 0 48 257 1 1
    RHEB CARHSP1 0 0 0 150 1 1
    RHEB RASGRP2 0 0 0 175 1 1
    RHEB ARF5 0 0 48 193 1 1
    RHEB PRKACG 0 0 0 252 1 1
    RHEB RELL2 188 0 0 197 1 1
    RHEB PEX19 0 0 157 175 1 1
    RHEB PIDD1 0 0 0 173 1 1
    RHEB ATP6V0E2 0 600 0 608 1 1
    RHEB NOTCH1 0 0 294 321 1 1
    RHEB MAST1 0 0 0 340 1 1
    RHEB MYO5A 0 0 64 170 1 1
    RHEB MYO9B 0 0 0 276 1 1
    RHEB AP1B1 0 0 0 237 1 1
    RHEB RHOU 0 0 83 164 1 1
    RHEB CALM1 0 0 61 158 1 1
    RHEB SUMO4 0 0 0 161 1 1
    RHEB PRKG1 0 0 161 266 1 1
    RHEB RAB12 0 0 0 212 1 2
    RHEB MYSM1 0 0 0 161 1 1
    RHEB VAV2 0 0 74 170 1 1
    RHEB IL6 0 0 247 246 1 1
    RHEB DOCK7 0 0 120 242 1 1
    RHEB FOXO6 0 0 181 358 1 1
    RHEB VPS4A 274 0 61 333 1 1
    RHEB RPS6 0 0 669 801 1 1
    RHEB ATP6V1H 0 600 0 624 1 1
    RHEB HIF1A 0 0 504 597 1 2
    RHEB GCK 0 0 134 259 1 1
    RHEB SH3BP4 0 0 310 309 1 1
    RHEB SIRT5 0 0 228 244 1 1
    RHEB ARHGEF4 0 0 67 278 1 1
    RHEB CCT5 0 0 0 163 1 1
    RHEB IL1B 0 0 173 173 1 1
    RHEB PSMC2 0 0 0 171 1 1
    RHEB RAB5B 0 0 81 199 1 1
    RHEB MAPKAPK5 0 0 392 405 1 1
    RHEB MAPK13 0 0 74 274 1 1
    RHEB RAB6B 0 0 0 273 1 1
    RHEB ADAP2 0 0 0 172 1 1
    RHEB CLN3 0 0 72 498 1 2
    RHEB CHM 0 0 0 198 1 1
    RHEB PPP2R2D 0 0 0 207 1 1
    RHEB DOCK1 0 0 47 179 1 1
    RHEB CDK2 0 0 232 478 1 1
    RHEB PDE7A 0 0 0 175 1 1
    RHEB MAP1LC3A 0 0 212 440 1 2
    RHEB EXOC8 0 0 125 294 1 1
    RHEB LIPE 0 0 140 156 1 1
    RHEB EPHA2 0 0 53 184 1 1
    RHEB GOLT1B 0 0 0 185 1 1
    RHEB RAB17 0 0 95 171 1 1
    RHEB ACSL3 0 0 0 152 1 1
    RHEB PRKAG1 0 900 71 941 1 1
    RHEB INPP5B 0 0 0 180 1 1
    RHEB ENSG00000270249 0 0 0 345 1 1
    RHEB PRKAR2B 0 0 81 283 1 1
    RHEB ARHGEF18 0 0 0 160 1 1
    RHEB PIK3R4 0 0 455 530 1 2
    RHEB TSNARE1 0 0 0 153 1 1
    RHEB PHLPP1 0 0 293 460 1 1
    RHEB LONRF2 0 0 0 179 1 1
    RHEB ATP6V1C2 0 600 0 653 1 1
    RHEB RAN 51 0 67 329 1 1
    RHEB FBXO42 0 0 0 176 1 1
    RHEB TEC 0 0 83 177 1 1
    RHEB ALDOA 0 0 43 192 1 1
    RHEB COPG1 0 0 0 195 1 1
    RHEB TUBB4A 0 0 48 161 1 1
    RHEB BCL2L1 0 0 386 402 1 2
    RHEB SMAD2 0 0 167 191 1 1
    RHEB KSR2 0 0 81 175 1 1
    RHEB TLR4 0 0 150 224 1 1
    RHEB AGFG2 0 0 0 154 1 1
    RHEB GSTO1 0 0 0 168 1 1
    RHEB RAB18 0 0 45 162 1 1
    RHEB TBC1D12 0 0 0 156 1 1
    RHEB ATG14 0 0 457 505 1 2
    RHEB TMEM102 0 0 162 161 1 1
    RHEB LARS2 0 0 573 640 1 1
    RHEB EGR3 0 0 107 183 1 1
    RHEB RAP1A 270 0 324 368 1 1
    RHEB GABARAPL2 0 0 400 512 1 2
    RHEB RPS6KA5 0 0 113 378 1 1
    RHEB RCE1 0 0 380 455 1 1
    RHEB BRSK2 0 0 357 427 1 1
    RHEB ABHD16A 0 0 48 217 1 1
    RHEB NF1 0 0 408 591 1 1
    RHEB GRB10 0 0 414 443 1 1
    RHEB NFATC2IP 130 0 0 219 1 1
    RHEB PRKACA 0 0 0 255 1 1
    RHEB TENC1 0 0 0 221 1 1
    RHEB MAPK4 0 0 0 201 1 1
    RHEB ARHGEF19 0 0 0 160 1 1
    RHEB ARL3 0 0 201 215 1 1
    RHEB TBC1D3H 0 0 0 156 1 1
    RHEB ADCY9 0 0 60 191 1 1
    RHEB ARF1 0 0 325 428 1 1
    RHEB TUBB1 0 0 0 155 1 1
    RHEB NSF 0 0 108 190 1 1
    RHEB MYH3 0 0 45 153 1 1
    RHEB NLGN3 0 0 123 164 1 1
    RHEB PLCG2 0 0 57 170 1 1
    RHEB CRACR2A 0 0 0 175 1 1
    RHEB GRTP1 0 0 0 181 1 1
    RHEB PDE11A 0 0 0 192 1 1
    RHEB PDE4C 0 0 0 175 1 1
    RHEB ANXA5 0 0 157 196 1 1
    RHEB CLPTM1 0 0 0 155 1 1
    RHEB CCNB1 0 0 123 207 1 1
    RHEB RAPGEF4 0 0 147 252 1 1
    RHEB AP3B1 0 0 0 190 1 1
    RHEB FBXO32 0 0 273 288 1 2
    RHEB TBC1D3E 0 0 0 156 1 1
    RHEB ENSG00000258472 0 0 0 203 1 1
    RHEB PRDX5 0 0 82 159 1 1
    RHEB ZKSCAN3 0 0 172 192 1 2
    RHEB CSDC2 0 0 0 150 1 1
    RHEB RANBP2 0 0 0 170 1 1
    RHEB C12orf66 0 900 324 929 1 1
    RHEB CUL7 0 0 100 156 1 1
    RHEB PPP2R2A 0 0 112 265 1 1
    RHEB IST1 0 0 0 169 1 1
    RHEB SIAH1 0 0 150 163 1 1
    RHEB PLK1 0 0 181 399 1 1
    RHEB GSTO2 0 0 0 360 1 1
    RHEB RELN 0 0 143 164 1 1
    RHEB ARHGEF2 0 0 57 174 1 1
    RHEB MCOLN3 0 0 90 241 1 1
    RHEB MCOLN2 0 0 62 221 1 1
    RHEB FKBP14 0 0 0 210 1 1
    RHEB CD8A 0 0 415 415 1 1
    RHEB ARFGAP3 0 0 73 182 1 1
    RHEB DEPDC5 0 900 519 966 1 1
    RHEB FUNDC1 0 0 260 277 1 2
    RHEB EXOC7 0 0 72 264 1 1
    RHEB TFAM 0 0 157 208 1 1
    RHEB LIMK2 0 0 0 172 1 1
    RHEB CREB3 117 0 97 174 1 1
    RHEB CLPX 0 0 0 197 1 1
    RHEB TCIRG1 0 600 62 629 1 1
    RHEB RSPH6A 0 0 134 177 1 1
    RHEB RTN1 0 0 0 167 1 1
    RHEB YWHAE 0 0 98 271 1 1
    RHEB PIP5K1A 0 0 70 163 1 1
    RHEB COPZ1 0 0 0 170 1 1
    RHEB VCP 0 0 96 174 1 2
    RHEB LCK 0 0 151 238 1 1
    RHEB LAMP2 130 0 466 547 1 2
    RHEB ACAP1 0 0 0 176 1 1
    RHEB SPOP 0 0 105 171 1 1
    RHEB GTPBP4 0 0 522 532 1 1
    RHEB USP4 270 0 73 324 1 1
    RHEB ERN2 0 0 60 157 1 1
    RHEB PIGC 0 0 0 226 1 1
    RHEB EIF1 0 0 181 199 1 1
    RHEB SHH 0 0 107 151 1 1
    RHEB BCL2L11 0 0 282 282 1 1
    RHEB TSC1 487 900 964 999 1 2
    RHEB ARFGEF2 0 0 0 195 1 1
    RHEB POLDIP3 0 0 261 310 1 1
    RHEB NR2F2 0 0 62 165 1 1
    RHEB MAPK12 0 0 90 286 1 1
    RHEB ITPR3 0 0 247 277 1 1
    RHEB PLCG1 0 0 124 229 1 1
    RHEB COPE 0 0 0 181 1 1
    RHEB FBXO8 0 0 45 158 1 1
    RHEB CHEK1 0 0 113 183 1 1
    RHEB SNAP29 0 0 89 165 1 2
    RHEB ECT2L 0 0 0 165 1 1
    RHEB SNCA 0 0 202 202 1 2
    RHEB AKT1S1 0 900 756 975 1 1
    RHEB CAV1 0 0 113 258 1 1
    RHEB SRF 0 0 128 178 1 1
    RHEB PRPSAP2 0 0 85 163 1 1
    RHEB ULK2 0 0 420 670 1 2
    RHEB ARL17B 0 0 0 171 1 1
    RHEB ENSG00000268434 0 0 0 151 1 1
    RHEB YBX2 0 0 0 150 1 1
    RHEB PLK5 0 0 0 222 1 1
    RHEB APPBP2 246 0 0 299 1 1
    RHEB RPS6KA6 0 0 91 320 1 1
    RHEB ATP6V1G2 0 600 0 618 1 1
    RHEB EXOC3 0 0 54 188 1 1
    RHEB FOXG1 0 0 0 273 1 1
    RHEB CIT 0 0 0 227 1 1
    RHEB ZNF185 0 0 0 153 1 1
    RHEB INS 0 0 757 757 1 1
    RHEB ACTB 0 0 346 399 1 1
    RHEB ZCCHC2 0 0 0 176 1 1
    RHEB MPND 0 0 0 159 1 1
    RHEB SIRT3 0 0 242 241 1 2
    RHEB BRCC3 0 0 0 159 1 1
    RHEB EXOC6B 0 0 0 180 1 1
    RHEB KEAP1 0 0 182 209 1 2
    RHEB PAX5 0 0 77 205 1 1
    RHEB ROS1 0 0 74 187 1 1
    RHEB FRMPD3 0 0 0 154 1 1
    RHEB FBXW7 0 0 170 220 1 1
    RHEB MYO9A 0 0 0 276 1 1
    RHEB ALDOB 0 0 0 156 1 1
    RHEB PNPLA2 0 0 156 155 1 1
    RHEB TFEB 0 0 556 575 1 2
    RHEB MYO1G 0 0 0 154 1 1
    RHEB NRBP1 0 0 0 180 1 1
    RHEB TOR1B 0 0 0 191 1 1
    RHEB ESR2 0 0 57 161 1 1
    RHEB USP6 0 0 324 421 1 1
    RHEB STK4 0 0 0 209 1 1
    RHEB RHOG 0 0 148 185 1 1
    RHEB NIM1K 0 0 0 154 1 1
    RHEB RAB1A 0 0 450 344 1 2
    RHEB PDK2 0 0 242 311 1 1
    RHEB GABARAPL1 0 0 406 532 1 2
    RHEB TUBA1B 0 0 0 256 1 1
    RHEB EIF3E 0 0 0 229 1 1
    RHEB ARSE 0 0 187 187 1 1
    RHEB ATP6V1E1 0 600 0 623 1 1
    RHEB CD24 0 0 65 163 1 1
    RHEB CCT4 0 0 0 333 1 1
    RHEB SIRT7 0 0 213 213 1 1
    RHEB EIF4G1 0 0 470 500 1 2
    RHEB RHOA 0 0 400 295 1 1
    RHEB PLXNA3 0 0 0 163 1 1
    RHEB HSPA8 0 0 174 228 1 2
    RHEB INSR 0 0 178 472 1 1
    RHEB CRTC2 0 0 181 181 1 1
    RHEB ZFYVE20 0 0 0 156 1 1
    RHEB AGAP6 0 0 0 154 1 1
    RHEB RAB24 0 0 124 164 1 2
    RHEB LLGL2 0 0 0 153 1 1
    RHEB GATSL3 0 900 505 950 1 1
    RHEB RHOQ 0 0 163 217 1 1
    RHEB OR8D2 0 0 162 161 1 1
    RHEB GUCY1A3 0 0 0 169 1 1
    RHEB ARAP2 0 0 0 154 1 1
    RHEB MAPKAPK2 0 0 113 168 1 1
    RHEB YWHAG 0 0 0 238 1 1
    RHEB CDK6 0 0 155 263 1 1
    RHEB RAB9B 0 0 0 196 1 1
    RHEB FRK 0 0 0 167 1 1
    RHEB RAB6C 0 0 0 283 1 1
    RHEB BMP7 0 0 55 213 1 1
    RHEB SLC3A2 0 0 370 385 1 1
    RHEB PIK3R5 0 0 273 273 1 1
    RHEB FKBP5 0 0 95 249 1 1
    RHEB PLCD4 0 0 0 194 1 1
    RHEB LGALS4 0 0 413 458 1 1
    RHEB STK32A 0 0 0 191 1 1
    RHEB BOLA2B 0 0 0 160 1 1
    RHEB PPP2R5A 0 0 163 233 1 1
    RHEB LLGL1 0 0 0 153 1 1
    RHEB MAVS 0 0 58 173 1 1
    RHEB DNM2 0 0 61 179 1 1
    RHEB RHOB 0 0 241 265 1 1
    RHEB MAP1LC3C 0 0 124 162 1 2
    RHEB CLPTM1L 0 0 0 155 1 1
    RHEB CASP8 0 0 161 176 1 2
    RHEB DCLK1 0 0 0 184 1 1
    RHEB PGK1 0 0 113 165 1 2
    RHEB RALGPS1 0 0 0 175 1 1
    RHEB GNB5 0 0 0 170 1 1
    RHEB ADCY5 0 0 66 197 1 1
    RHEB TBC1D10A 0 0 0 156 1 1
    RHEB CSNK2A2 0 0 123 176 1 1
    RHEB ENSG00000272822 0 0 0 171 1 1
    RHEB PLCL2 0 0 0 194 1 1
    RHEB ARL17A 0 0 0 171 1 1
    RHEB CNTF 0 0 154 153 1 1
    RHEB TUBB3 0 0 0 162 1 1
    RHEB TBC1D3I 0 0 0 156 1 1
    RHEB HK1 0 0 54 174 1 1
    RHEB CASP9 0 0 181 196 1 1
    RHEB ATG4A 0 0 49 171 1 2
    RHEB TBC1D15 0 0 71 212 1 1
    RHEB RPS6KA4 0 0 66 246 1 1
    RHEB ITPR1 0 0 171 204 1 2
    RHEB PLK2 0 0 0 238 1 1
    RHEB EXOC6 0 0 53 190 1 1
    RHEB RPS6KA3 0 0 470 610 1 1
    RHEB MAPK9 0 0 134 210 1 2
    RHEB RAB8B 0 0 0 265 1 2
    RHEB PRKAB2 0 900 123 915 1 1
    RHEB RAB31 0 0 0 157 1 1
    RHEB FASN 0 0 217 229 1 1
    RHEB EIF4A3 0 0 0 171 1 1
    RHEB SOS2 0 0 0 195 1 1
    RHEB DIAPH2 0 0 0 160 1 1
    RHEB IQSEC3 0 0 81 212 1 1
    RHEB PDE2A 0 0 0 175 1 1
    RHEB RDX 0 0 99 195 1 1
    RHEB RPTOR 947 900 988 999 1 2
    RHEB NES 0 0 123 261 1 1
    RHEB RABL6 0 0 0 182 1 1
    RHEB TBC1D5 0 0 0 161 1 2
    RHEB TRIB1 0 0 0 169 1 1
    RHEB GNAS 0 0 103 253 1 1
    RHEB ARHGEF9 0 0 0 258 1 1
    RHEB TBC1D9B 0 0 0 190 1 1
    RHEB MRPL11 0 0 0 167 1 1
    RHEB PAK3 0 0 0 229 1 1
    RHEB ACAP3 0 0 0 172 1 1
    RHEB TNS1 0 0 390 504 1 1
    RHEB KRIT1 0 0 0 155 1 1
    RHEB SPRED3 0 0 0 182 1 1
    RHEB HIST2H3PS2 0 0 160 159 1 1
    RHEB PXN 0 0 138 275 1 1
    RHEB CSK 0 0 56 191 1 1
    RHEB RPS6KB2 0 0 560 848 1 2
    RHEB OMG 0 0 70 151 1 1
    RHEB FKBP1A 0 0 681 777 1 2
    RHEB NR3C1 0 0 108 220 1 1
    RHEB SMARCB1 0 0 292 292 1 1
    RHEB ADIPOQ 0 0 194 194 1 1
    RHEB SHANK2 0 0 127 328 1 1
    RHEB AGAP10 0 0 0 154 1 1
    RHEB RUVBL1 0 0 194 247 1 1
    RHEB ACAP2 0 0 0 172 1 1
    RHEB SUMO3 0 0 45 183 1 1
    RHEB FZD7 0 0 48 177 1 1
    RHEB PRKAB1 0 900 261 932 1 2
    RHEB SKP2 0 0 155 203 1 1
    RHEB RAPGEF1 0 0 0 175 1 1
    RHEB ATP6V0A2 0 0 75 160 1 1
    RHEB RAB36 0 0 0 256 1 1
    RHEB PAK2 0 0 43 248 1 1
    RHEB RAB38 0 0 52 480 1 1
    RHEB RAB40A 0 0 0 240 1 1
    RHEB PLEKHA4 270 0 0 285 1 1
    RHEB CDK17 0 0 0 269 1 1
    RHEB IQGAP2 0 0 60 251 1 1
    RHEB ICMT 0 0 293 394 1 1
    RHEB ITSN2 0 0 0 196 1 1
    RHEB PLXNB2 0 0 0 163 1 1
    RHEB LAMTOR3 0 600 646 862 1 1
    RHEB SOS1 0 0 181 313 1 1
    RHEB SOCS1 0 0 146 162 1 1
    RHEB KNSTRN 0 0 147 191 1 1
    RHEB BTK 0 0 182 266 1 1
    RHEB NEDD4L 0 0 81 173 1 1
    RHEB CCND3 0 0 140 207 1 1
    RHEB CYTH3 0 0 52 164 1 1
    RHEB WDFY3 0 0 171 302 1 2
    RHEB MAPK1 0 0 241 422 1 2
    RHEB PPP2R1A 0 0 133 197 1 1
    RHEB IGF1 0 0 556 568 1 1
    RHEB EPHB4 0 0 0 166 1 1
    RHEB SRPRB 130 0 72 168 1 1
    RHEB PKM 0 0 213 252 1 1
    RHEB ESRRB 0 0 44 170 1 1
    RHEB GNAI2 0 0 0 214 1 1
    RHEB DAAM2 0 0 0 204 1 1
    RHEB CD44 0 0 157 156 1 1
    RHEB SLC1A5 0 0 324 353 1 1
    RHEB BDNF 0 0 294 337 1 2
    RHEB SMAP2 0 0 0 174 1 1
    RHEB TUBB4B 0 0 0 240 1 1
    RHEB YBX1 0 0 52 160 1 1
    RHEB VPS25 0 0 60 289 1 1
    RHEB PSD2 0 0 0 154 1 1
    RHEB IGBP1 0 0 68 287 1 1
    RHEB TSSK1B 0 0 0 154 1 1
    RHEB ATP11B 0 0 171 208 1 1
    RHEB AP3S1 0 0 0 187 1 1
    RHEB TBC1D10C 0 0 0 156 1 1
    RHEB GLS2 0 0 140 159 1 1
    RHEB FGD2 0 0 0 160 1 1
    RHEB PPP2R5E 0 0 93 171 1 1
    RHEB MAP2K2 0 0 186 431 1 1
    RHEB NAA20 0 0 53 157 1 1
    RHEB PHLPP2 0 0 144 381 1 1
    RHEB EVL 0 0 0 182 1 1
    RHEB ADCY2 0 0 0 172 1 1
    RHEB MYH2 0 0 49 156 1 1
    RHEB TBC1D17 0 0 150 282 1 1
    RHEB RAB34 0 0 155 283 1 1
    RHEB PLCE1 0 0 0 211 1 1
    RHEB MYO1B 0 0 66 171 1 1
    RHEB PSD 0 0 0 154 1 1
    RHEB TUBA1A 0 0 63 190 1 1
    RHEB DCLK2 0 0 0 184 1 1
    RHEB GNB2L1 0 0 163 270 1 1
    RHEB TSSK2 0 0 0 154 1 1
    RHEB INF2 0 0 0 207 1 1
    RHEB RUNX1 0 0 306 346 1 1
    RHEB MYCBP2 0 0 103 166 1 1
    RHEB UBB 131 0 0 209 1 1
    RHEB ENSG00000264813 0 0 81 195 1 1
    RHEB INADL 0 0 91 183 1 1
    RHEB MAP4K3 0 0 468 561 1 1
    RHEB TXN 0 0 126 206 1 1
    RHEB CCNE1 0 0 95 234 1 1
    RHEB FH 0 0 150 202 1 1
    RHEB ACTR10 0 0 0 156 1 1
    RHEB PRPS2 0 0 102 160 1 1
    RHEB PIK3C2B 0 0 159 264 1 1
    RHEB IPMK 0 0 123 176 1 1
    RHEB HMGCR 0 0 167 204 1 1
    RHEB PPP2CA 0 0 138 261 1 1
    RHEB PRKDC 0 0 122 231 1 2
    RHEB WDR86 0 0 154 161 1 1
    RHEB PAK6 0 0 0 229 1 1
    RHEB EIF4E 0 900 682 975 1 1
    RHEB YWHAQ 0 0 92 279 1 1
    RHEB KAT2B 0 0 49 153 1 1
    RHEB RAB33A 0 0 0 211 1 1
    RHEB BAD 0 0 206 235 1 1
    RHEB SEMA3A 0 0 95 165 1 1
    RHEB COPB1 0 0 0 261 1 1
    RHEB AGAP5 0 0 0 154 1 1
    RHEB NOS3 0 0 170 169 1 1
    RHEB CCND1 0 0 371 398 1 1
    RHEB TBC1D20 0 0 81 152 1 1
    RHEB PRKAA1 0 900 155 948 1 2
    RHEB LRGUK 0 0 0 181 1 1
    RHEB AP1G2 0 0 0 196 1 1
    RHEB WNT9A 0 0 66 171 1 1
    RHEB ENSG00000257390 0 0 0 157 1 1
    RHEB ATP6V1F 0 600 45 610 1 1
    RHEB NCF1 0 0 61 273 1 1
    RHEB CDC42 0 0 324 260 1 1
    RHEB SLC2A4 0 0 336 379 1 1
    RHEB FOXO3 0 0 493 838 1 2
    RHEB GATA5 0 0 0 183 1 1
    RHEB FBXW5 0 0 398 398 1 1
    RHEB APOE 0 0 74 186 1 1
    RHEB RAPGEF2 0 0 107 214 1 1
    RHEB FMNL1 0 0 0 243 1 1
    RHEB WDR24 0 900 459 973 1 1
    RHEB RTN3 0 0 0 167 1 1
    RHEB MAP3K19 0 0 0 262 1 1
    RHEB USP6NL 0 0 0 156 1 1
    RHEB MYO1E 0 0 55 162 1 1
    RHEB RASA3 0 0 0 560 1 1
    RHEB ENSG00000268465 0 0 0 154 1 1
    RHEB PSMD7 0 0 0 175 1 1
    RHEB DTD1 0 0 0 192 1 1
    RHEB TXNDC9 0 0 242 287 1 1
    RHEB MCRS1 0 0 912 913 1 1
    RHEB ARHGAP27 0 0 0 270 1 1
    RHEB ATG3 0 0 391 477 1 2
    RHEB CDKN3 0 0 134 236 1 1
    RHEB BIRC6 0 0 0 166 1 1
    RHEB KDR 0 0 127 262 1 2
    RHEB SKP1 0 0 123 179 1 1
    RHEB YY1 0 0 205 224 1 1
    RHEB RAB11A 0 0 206 204 1 1
    RHEB RAC2 0 0 688 337 1 1
    RHEB PARD6G 0 0 0 173 1 1
    RHEB CHML 0 0 52 208 1 1
    RHEB TBK1 0 0 151 255 1 2
    RHEB ATG2B 0 0 125 160 1 2
    RHEB TUBB2A 0 0 0 167 1 1
    RHEB FOXP3 0 0 218 235 1 1
    RHEB PTPN6 0 0 0 195 1 1
    RHEB LAPTM4B 0 0 113 188 1 1
    RHEB TBC1D3K 0 0 0 156 1 1
    RHEB PRKCD 0 0 123 271 1 2
    RHEB TBC1D3 0 0 66 178 1 1
    RHEB RIPK3 0 0 49 150 1 1
    RHEB ZCCHC13 0 0 0 171 1 1
    RHEB ADCY4 0 0 0 172 1 1
    RHEB PIP4K2B 0 0 48 173 1 1
    RHEB VDAC1 0 0 171 234 1 2
    RHEB RASSF5 0 0 67 159 1 1
    RHEB LRIT3 0 0 0 154 1 1
    RHEB CNBD2 0 0 0 251 1 1
    RHEB STAT5B 0 0 142 165 1 1
    RHEB RAB7B 0 0 455 275 1 1
    RHEB RASGRF2 0 0 0 175 1 1
    RHEB PIK3C2A 0 0 123 232 1 2
    RHEB MAGOH 0 0 113 170 1 1
    RHEB VAMP7 0 0 70 207 1 1
    RHEB IQSEC2 0 0 0 154 1 1
    RHEB TIAM1 0 0 137 407 1 1
    RHEB MAF1 0 900 123 916 1 1
    RHEB PPP2R3B 0 0 74 167 1 1
    RHEB MBTPS1 0 0 142 192 1 1
    RHEB INPP5D 0 0 164 216 1 1
    RHEB CDK18 0 0 0 269 1 1
    RHEB TBC1D26 0 0 0 156 1 1
    RHEB KLHDC9 0 0 0 176 1 1
    RHEB PREX2 0 0 60 285 1 1
    RHEB EFNB3 0 0 367 367 1 1
    RHEB VMP1 0 0 209 209 1 2
    RHEB NOX4 0 0 122 159 1 1
    RHEB ARF4 0 0 69 235 1 1
    RHEB TPT1 270 0 914 976 1 1
    RHEB MCFD2 0 0 0 153 1 1
    RHEB NTRK2 0 0 171 256 1 1
    RHEB PDE6D 935 0 445 970 1 1
    RHEB ARHGEF15 0 0 0 160 1 1
    RHEB EIF4EBP1 800 900 803 996 1 1
    RHEB RTN4 0 0 88 203 1 1
    RHEB FOXO4 0 0 245 259 1 1
    RHEB AXL 0 0 60 157 1 1
    RHEB PTPN23 0 0 0 158 1 1
    RHEB MYH4 0 0 0 166 1 1
    RHEB GRM5 0 0 180 190 1 1
    RHEB PINK1 0 0 322 389 1 2
    RHEB UBQLN1 51 0 67 160 1 2
    RHEB SPATA13 0 0 0 258 1 1
    RHEB PHGDH 0 0 151 165 1 1
    RHEB PDE5A 0 0 0 179 1 1
    RHEB PKHD1L1 0 0 0 163 1 1
    RHEB YES1 0 0 43 169 1 1
    RHEB FOXF1 0 0 0 162 1 1
    RHEB PSMC1 0 0 0 156 1 1
    RHEB TUBAL3 0 0 0 164 1 1
    RHEB NEDD8-MDP1 0 0 0 221 1 1
    RHEB CREM 0 0 150 295 1 1
    RHEB SYNGAP1 0 0 125 214 1 1
    RHEB ARHGEF12 0 0 74 188 1 1
    RHEB PDE4B 0 0 0 321 1 1
    RHEB PDE7B 0 0 0 175 1 1
    RHEB PDE6A 0 0 0 175 1 1
    RHEB TFE3 0 0 324 452 1 1
    RHEB HSPA5 0 0 245 309 1 2
    RHEB NRAS 0 0 325 189 1 1
    RHEB MYO3B 0 0 0 170 1 1
    RHEB EIF4A2 0 0 391 480 1 1
    RHEB ARHGEF1 0 0 90 202 1 1
    RHEB ARHGEF5 0 0 0 160 1 1
    RHEB SEC11A 0 0 0 150 1 1
    RHEB EPAS1 0 0 0 221 1 2
    RHEB FOXO1 0 0 517 530 1 2
    RHEB TGFB1I1 0 0 0 193 1 1
    RHEB DUSP3 0 0 0 152 1 1
    RHEB CDK9 0 0 194 212 1 1
    RHEB ENSG00000279058 0 0 0 154 1 1
    RHEB FOS 0 0 181 245 1 1
    RHEB YWHAZ 0 0 84 227 1 1
    RHEB TBC1D2B 0 0 0 173 1 1
    RHEB PTK6 0 0 90 183 1 1
    RHEB PNPLA7 0 0 0 161 1 1
    RHEB TBC1D10B 0 0 0 156 1 1
    RHEB GAB1 0 0 123 176 1 1
    RHEB PTPN11 0 0 211 341 1 1
    RHEB MSTN 0 0 280 297 1 1
    RHEB RAB11B 0 0 0 159 1 1
    RHEB RRAGC 0 600 840 965 1 1
    RHEB COPS6 0 0 0 164 1 1
    RHEB RRAGD 0 600 720 939 1 1
    RHEB WAS 0 0 64 221 1 1
    RHEB RABGAP1 0 0 0 176 1 1
    RHEB ADCY3 0 0 0 172 1 1
    RHEB ARHGAP35 0 0 73 207 1 1
    RHEB NELFA 0 0 107 162 1 1
    RHEB GNAI3 0 0 0 214 1 2
    RHEB SDC1 0 0 51 154 1 1
    RHEB TBC1D21 0 0 0 156 1 1
    RHEB STK38L 0 0 0 184 1 1
    RHEB ATP6V0E1 0 600 0 608 1 1
    RHEB ARF6 0 0 166 236 1 1
    RHEB EIF4EBP2 0 0 456 783 1 1
    RHEB EEF2K 0 0 394 394 1 2
    RHEB ADCY10 0 0 0 169 1 1
    RHEB PMAIP1 0 0 151 150 1 1
    RHEB PIK3CB 0 0 392 551 1 1
    RHEB TLR2 0 0 91 170 1 1
    RHEB PRKCH 0 0 67 225 1 1
    RHEB PIM3 0 0 0 154 1 1
    RHEB PLXNA4 0 0 0 163 1 1
    RHEB ERF 0 0 0 174 1 1
    RHEB MET 0 0 134 319 1 1
    RHEB PHB 270 0 69 386 1 1
    RHEB LRRK2 0 0 360 616 1 2
    RHEB ABHD11 0 0 0 291 1 1
    RHEB GNAO1 0 0 0 214 1 1
    RHEB GRIN2B 0 0 134 166 1 1
    RHEB GDI1 0 0 0 198 1 1
    RHEB PRKCQ 0 0 113 289 1 2
    RHEB ATG12 0 0 459 572 1 2
    RHEB TAF6 0 0 0 189 1 1
    RHEB CD28 0 0 202 202 1 1
    RHEB ENTHD1 0 0 0 165 1 1
    RHEB NR2C2 270 0 0 350 1 1
    RHEB ARHGEF38 0 0 0 258 1 1
    RHEB ATG4D 0 0 170 274 1 2
    RHEB ESRRG 0 0 66 189 1 1
    RHEB UFL1 0 0 0 159 1 1
    RHEB MYH8 0 0 0 159 1 1
    RHEB TRIB3 0 0 96 202 1 1
    RHEB ARHGAP29 0 0 67 190 1 1
    RHEB RPS6KC1 0 0 123 236 1 1
    RHEB LNX1 0 0 0 204 1 1
    RHEB GNA15 0 0 155 275 1 1
    RHEB TBC1D9 0 0 0 174 1 1
    RHEB ATP6V1B2 0 600 74 639 1 1
    RHEB LIMK1 0 0 63 222 1 1
    RHEB EEF1A1 0 0 113 164 1 1
    RHEB ARHGEF35 0 0 0 160 1 1
    RHEB AP1G1 0 0 0 222 1 1
    RHEB EPHA5 0 0 81 362 1 1
    RHEB SNTB1 0 0 52 182 1 1
    RHEB RAB4B 0 0 76 163 1 1
    RHEB TUBE1 0 0 0 155 1 1
    RHEB PI4KA 0 0 0 209 1 1
    RHEB AP1M2 0 0 0 325 1 1
    RHEB STK24 0 0 181 235 1 1
    RHEB RACGAP1 0 0 54 172 1 1
    RHEB LAMTOR1 0 600 592 864 1 1
    RHEB YWHAH 0 0 45 195 1 1
    RHEB PHB2 0 0 92 170 1 1
    RHEB CCDC141 0 0 54 184 1 1
    RHEB COPA 0 0 0 248 1 1
    RHEB GOLGA1 0 0 0 173 1 1
    RHEB SFN 0 0 44 160 1 1
    RHEB EPHA3 0 0 0 172 1 1
    RHEB TBC1D1 0 0 154 208 1 1
    RHEB MYH1 0 0 0 166 1 1
    RHEB ATP6V1C1 0 600 0 660 1 1
    RHEB ARFGAP1 0 0 74 183 1 1
    RHEB WNT2 0 0 66 186 1 1
    RHEB KLF2 0 0 155 176 1 1
    RHEB CUL3 0 0 89 167 1 1
    RHEB CHUK 0 0 174 322 1 1
    RHEB PDE6C 0 0 47 180 1 1
    RHEB JAZF1 0 0 0 160 1 1
    RHEB RET 0 0 146 200 1 1
    RHEB MAST4 0 0 56 570 1 1
    RHEB EIF3D 0 0 0 197 1 1
    RHEB GNAI1 0 0 0 214 1 1
    RHEB ENSG00000267261 0 0 0 283 1 1
    RHEB POLI 0 0 171 171 1 1
    RHEB CTSD 0 0 151 186 1 2
    RHEB AXIN1 0 0 208 235 1 1
    RHEB EIF3F 0 0 407 495 1 1
    RHEB TRIM63 192 0 253 380 1 1
    RHEB EZR 0 0 123 199 1 1
    RHEB PWP1 0 0 0 169 1 1
    RHEB SHC1 0 0 293 364 1 1
    RHEB ENSG00000278299 0 0 66 178 1 1
    RHEB ATM 270 0 335 541 1 1
    RHEB PLEKHG4B 0 0 0 246 1 1
    RHEB STX12 0 0 0 175 1 1
    RHEB PRKAG3 0 900 73 917 1 1
    RHEB DAP 0 0 245 310 1 2
    RHEB ATP6V0A1 0 0 108 208 1 1
    RHEB FMN1 0 0 0 242 1 1
    RHEB PTK7 0 0 0 189 1 1
    RHEB MON2 0 0 0 306 1 1
    RHEB PLXNB3 0 0 0 163 1 1
    RHEB EXOC4 0 0 58 235 1 1
    RHEB RXRG 0 0 54 158 1 1
    RHEB EGLN2 0 0 102 151 1 1
    RHEB ATG7 0 0 506 638 1 2
    RHEB ACTG1 0 0 69 152 1 1
    RHEB TAF6L 0 0 0 189 1 1
    RHEB AP4B1 0 0 0 200 1 1
    RHEB MYOD1 0 0 129 153 1 1
    RHEB CNKSR1 0 0 97 205 1 1
    RHEB DNM1L 0 0 189 241 1 2
    RHEB WIPI1 0 0 358 396 1 2
    RHEB GPR52 0 0 66 169 1 1
    RHEB PI4KB 0 0 66 182 1 1
    RHEB PRKAA2 0 900 295 957 1 2
    RHEB VEGFA 0 0 335 335 1 1
    RHEB GABARAP 0 0 373 506 1 2
    RHEB STXBP5L 0 0 0 153 1 1
    RHEB MAPK7 0 0 134 321 1 1
    RHEB PTEN 0 0 662 900 1 2
    RHEB RAB5C 0 0 0 203 1 1
    RHEB CYFIP2 0 0 0 179 1 1
    RHEB ARL2 0 0 391 432 1 1
    RHEB BET1 0 0 0 190 1 1
    RHEB CFL1 0 0 81 176 1 1
    RHEB ENSG00000258947 0 0 0 162 1 1
    RHEB LMNB2 0 0 170 182 1 1
    RHEB MAPK14 0 0 171 350 1 1
    RHEB SARNP 0 0 0 167 1 1
    RHEB MAPK10 0 0 66 153 1 2
    RHEB SREBF1 0 0 390 500 1 2
    RHEB AP2A1 0 0 0 198 1 1
    RHEB SLC36A4 0 0 309 335 1 1
    RHEB MAP3K3 0 0 73 287 1 1
    RHEB ATAD2B 0 0 0 164 1 1
    RHEB ASAP2 0 0 0 172 1 1
    RHEB PLXNC1 0 0 0 163 1 1
    RHEB PRKG2 0 0 0 161 1 1
    RHEB C12orf5 0 0 223 246 1 1
    RHEB LEP 0 0 213 213 1 1
    RHEB SYK 0 0 90 183 1 1
    RHEB GBA2 0 0 0 178 1 1
    RHEB MAP3K5 0 0 193 193 1 1
    RHEB GNA11 0 0 181 297 1 1
    RHEB BACE1 0 0 265 295 1 1
    RHEB DGKA 0 0 149 167 1 1
    RHEB TUBB 0 0 0 208 1 1
    RHEB ARHGDIG 0 0 0 252 1 1
    RHEB GATA2 0 0 81 159 1 1
    RHEB LYN 0 0 106 198 1 1
    RHEB COPS5 0 0 0 201 1 1
    RHEB TBC1D3L 0 0 0 156 1 1
    RHEB RAB13 0 0 181 279 1 2
    RHEB MAPK6 0 0 119 282 1 1
    RHEB PPP1CA 0 0 85 215 1 1
    RHEB RAC1 129 0 183 301 1 1
    RHEB CTSB 0 0 108 154 1 2
    RHEB DPM1 0 0 0 151 1 1
    RHEB UBTF 0 0 120 188 1 1
    RHEB SIRT1 0 0 336 374 1 2
    RHEB GMIP 0 0 0 168 1 1
    RHEB DDIT4L 0 0 457 476 1 1
    RHEB DLK1 0 0 74 287 1 1
    RHEB MCL1 0 0 322 321 1 2
    RHEB STAT2 0 0 42 157 1 1
    RHEB ENSG00000256349 0 0 0 226 1 1
    RHEB PCNA 43 0 0 192 1 1
    RHEB GIT1 0 0 72 308 1 1
    RHEB XBP1 0 0 240 253 1 2
    RHEB SMC1B 0 0 0 168 1 1
    RHEB PTPN1 0 0 134 216 1 1
    RHEB PUM1 0 0 0 158 1 1
    RHEB GATA6 0 0 0 183 1 1
    RHEB PRKAG2 0 900 180 948 1 1
    RHEB KSR1 0 0 175 260 1 1
    RHEB VGLL1 0 0 0 213 1 1
    RHEB ATG5 0 0 509 641 1 2
    RHEB YIPF1 0 0 166 186 1 1
    RHEB PPP2R2C 0 0 0 207 1 1
    RHEB WNT3A 0 0 89 181 1 1
    RHEB GRIN1 0 0 45 167 1 1
    RHEB CYTH1 0 0 66 176 1 1
    RHEB WDFY4 0 0 0 192 1 1
    RHEB GCC1 0 0 48 183 1 1
    RHEB KPTN 0 900 294 926 1 1
    RHEB GUCY1B3 0 0 0 169 1 1
    RHEB C15orf38-AP3S2 0 0 0 156 1 1
    RHEB PSD3 0 0 0 154 1 1
    RHEB ATG10 0 0 326 332 1 2
    RHEB FNIP1 0 0 402 423 1 1
    RHEB PSMD14 0 0 0 256 1 1
    RHEB AP2S1 0 0 0 191 1 1
    RHEB PARD6B 0 0 0 173 1 1
    RHEB RALA 0 0 509 188 1 1
    RHEB RARA 0 0 70 172 1 1
    RHEB DYNLL2 0 0 0 209 1 1
    RHEB TBC1D3G 0 0 0 156 1 1
    RHEB BBS9 0 0 0 153 1 1
    RHEB AKT3 0 0 458 710 1 1
    RHEB SEC22B 0 0 54 161 1 1
    RHEB SLC7A14 0 0 0 151 1 1
    RHEB MFSD8 0 0 71 242 1 1
    RHEB RPS6KA1 0 0 609 707 1 1
    RHEB NR2E3 0 0 0 150 1 1
    RHEB SOD3 0 0 48 215 1 1
    RHEB NEK2 0 0 0 242 1 1
    RHEB MAP3K12 0 0 72 172 1 1
    RHEB TBX21 0 0 181 193 1 1
    RHEB RGPD3 0 0 0 153 1 1
    RHEB TBC1D14 0 0 0 156 1 2
    RHEB LATS1 0 0 142 185 1 1
    RHEB HSD17B3 0 0 0 153 1 1
    RHEB ARFGAP2 0 0 0 154 1 1
    RHEB ITFG2 0 900 271 924 1 1
    RHEB SLC2A3 0 0 140 196 1 1
    RHEB SPATA6L 0 0 145 286 1 1
    RHEB FLNA 0 0 95 180 1 1
    RHEB MKNK2 0 0 126 205 1 1
    RHEB TFEC 0 0 167 283 1 1
    RHEB PBK 0 0 49 150 1 1
    RHEB CYFIP1 0 0 74 205 1 1
    RHEB GOLPH3 0 0 123 233 1 1
    RHEB DUSP4 0 0 61 150 1 1
    RHEB VPS39 0 0 486 646 1 1
    RHEB RB1CC1 0 600 556 855 1 2
    RHEB BRCA1 0 0 151 150 1 1
    RHEB STK11 0 0 654 762 1 2
    RHEB ARHGAP11B 0 0 0 198 1 1
    RHEB PEX1 0 0 57 210 1 1
    RHEB PLXNA2 0 0 0 163 1 1
    RHEB CHN2 0 0 0 168 1 1
    RHEB BOLA2 0 0 0 166 1 1
    RHEB SLC1A3 0 0 81 282 1 1
    RHEB PLCL1 0 0 0 194 1 1
    RHEB RAB11FIP5 0 0 53 175 1 1
    RHEB PARK2 0 0 247 304 1 1
    RHEB WNT5A 0 0 66 161 1 1
    RHEB ILK 0 0 155 185 1 1
    RHEB RALGDS 0 0 294 380 1 1
    RHEB PPARGC1A 0 0 343 345 1 1
    RHEB AP5M1 0 0 0 195 1 1
    RHEB P4HB 0 0 113 155 1 2
    RHEB ATP6V1G1 0 600 0 620 1 1
    RHEB G6PC 0 0 174 190 1 1
    RHEB EFTUD2 0 0 0 176 1 1
    RHEB PIM1 0 0 0 154 1 1
    RHEB RICTOR 0 0 765 920 1 2
    RHEB ENSG00000261832 0 0 67 495 1 1
    RHEB DVL1 0 0 95 185 1 1
    RHEB GNAQ 0 0 144 265 1 1
    RHEB PIK3R3 0 0 294 342 1 1
    RHEB ARHGEF28 0 0 0 184 1 1
    RHEB ARHGAP19 0 0 0 168 1 1
    RHEB TUBA3D 0 0 0 159 1 1
    RHEB JAK2 0 0 162 261 1 1
    RHEB VAMP8 0 0 113 196 1 2
    RHEB GNAT1 0 0 0 214 1 1
    RHEB MKNK1 0 0 216 239 1 1
    RHEB GBF1 0 0 53 165 1 1
    RHEB EXOC2 0 0 170 303 1 1
    RHEB CHN1 0 0 0 168 1 1
    RHEB HDAC6 0 0 144 178 1 2
    RHEB MELK 0 0 0 154 1 1
    RHEB RGL4 0 0 0 159 1 1
    RHEB CALM3 0 0 66 162 1 1
    RHEB PPARD 0 0 71 173 1 1
    RHEB ADCY1 0 0 0 172 1 1
    RHEB GNGT1 0 0 365 365 1 1
    RHEB FMN2 0 0 0 233 1 1
    RHEB FHOD3 0 0 0 176 1 1
    RHEB MYH6 0 0 122 221 1 1
    RHEB FGD4 0 0 0 160 1 1
    RHEB PRKAR2A 0 0 101 298 1 1
    RHEB MCOLN1 0 0 235 334 1 1
    RHEB RAB8A 0 0 183 291 1 2
    RHEB EIF2AK4 0 0 390 495 1 1
    RHEB RHBDL3 0 0 0 165 1 1
    RHEB ITGB8 232 0 0 273 1 1
    RHEB CD300C 0 0 235 235 1 1
    RHEB C7orf60 0 900 310 929 1 1
    RHEB GDNF 0 0 144 163 1 1
    RHEB RASGRP3 0 0 57 217 1 1
    RHEB TRIM16 0 0 70 152 1 2
    RHEB DOCK3 0 0 57 188 1 1
    RHEB MDM2 0 0 323 323 1 1
    RHEB TP53 0 0 459 463 1 2
    RHEB RASEF 0 0 0 174 1 1
    RHEB RASGRP1 0 0 261 364 1 1
    RHEB ENSG00000273637 0 0 0 504 1 1
    RHEB NR1H2 0 0 0 183 1 1
    RHEB RAB2A 0 0 135 158 1 1
    RHEB YIF1A 0 0 0 239 1 1
    RHEB LAMP1 0 0 363 440 1 2
    RHEB AMHR2 0 0 0 200 1 1
    RHEB SLC2A1 0 0 370 432 1 1
    RHEB FGFR3 43 0 150 205 1 1
    RHEB HTT 270 0 826 898 1 1
    RHEB PPP1CC 0 0 90 191 1 1
    RHEB MAP3K13 0 0 54 156 1 1
    RHEB EGFR 0 0 392 481 1 1
    RHEB RAF1 766 0 498 901 1 2
    RHEB IRAK1 0 0 75 170 1 1
    RHEB CRYGN 0 0 66 273 1 1
    RHEB FHOD1 0 0 47 202 1 1
    RHEB RALGAPA1 0 0 164 258 1 1
    RHEB TNS3 0 0 0 221 1 1
    RHEB SLC7A5 0 0 458 466 1 1
    RHEB WNT4 0 0 61 156 1 1
    RHEB TBC1D13 0 0 0 191 1 1
    RHEB MAP3K7 0 0 136 243 1 1
    RHEB DNAJA1 0 0 124 258 1 1
    RHEB RAB10 0 0 493 371 1 1
    RHEB EDA 0 0 0 189 1 1
    RHEB ENSG00000273217 0 0 0 152 1 1
    RHEB MAP1A 0 0 143 194 1 1
    RHEB ARAF 0 0 280 420 1 1
    RHEB SPNS1 0 0 71 160 1 2
    RHEB TRAPPC8 0 0 57 164 1 1
    RHEB TRIB2 0 0 0 164 1 1
    RHEB MTOR 972 900 989 999 1 2
    RHEB MAPKAP1 0 0 565 724 1 1
    RHEB PIK3C3 0 0 643 802 1 2
    RHEB MAP3K2 0 0 0 262 1 1
    RHEB MAPRE1 0 0 0 155 1 1
    RHEB GNA13 0 0 0 213 1 1
    RHEB MPP5 0 0 67 192 1 1
    RHEB GATSL2 0 900 241 924 1 1
    RHEB STAT1 0 0 123 290 1 1
    RHEB COG6 0 0 0 162 1 1
    RHEB SOCS5 0 0 143 178 1 1
    RHEB ELAVL3 0 0 218 226 1 1
    RHEB PLEK 0 0 508 521 1 1
    RHEB TBC1D16 0 0 0 156 1 1
    RHEB NPHS1 0 0 56 253 1 1
    RHEB NEDD4 0 0 150 235 1 2
    RHEB RPL12 0 0 0 167 1 1
    RHEB BBS1 0 0 0 226 1 1
    RHEB RAB5A 0 0 373 292 1 2
    RHEB TBCCD1 0 0 107 445 1 1
    RHEB NR1H3 0 0 0 183 1 1
    RHEB CNBP 0 0 0 171 1 1
    RHEB RALGAPA2 0 0 74 204 1 1
    RHEB NDRG1 0 0 170 202 1 1
    RHEB SGSM2 0 0 0 156 1 1
    RHEB ARHGEF11 0 0 0 160 1 1
    RHEB SUMO2 0 0 0 161 1 1
    RHEB PAX2 0 0 0 174 1 1
    RHEB ARF3 0 0 459 532 1 1
    RHEB SLC1A7 0 0 459 459 1 1
    RHEB ASAP1 0 0 0 172 1 1
    RHEB CTNNB1 0 0 315 359 1 1
    RHEB ATP6V1B1 0 600 0 620 1 1
    RHEB HRAS 270 0 464 399 1 1
    RHEB ENSG00000258989 0 0 0 203 1 1
    RHEB TBC1D30 0 0 0 173 1 1
    RHEB APP 0 0 171 192 1 1
    RHEB MFN2 0 0 189 241 1 2
    RHEB PASK 0 0 0 251 1 1
    RHEB WNT2B 0 0 73 167 1 1
    RHEB TGFBRAP1 0 0 118 267 1 1
    RHEB DCLK3 0 0 0 184 1 1
    RHEB RHOBTB1 0 0 74 197 1 1
    RHEB IKBKE 0 0 62 177 1 1
    RHEB ARC 0 0 123 163 1 1
    RHEB TRIM25 0 0 0 201 1 1
    RHEB STAT4 0 0 124 158 1 1
    RHEB ARHGAP4 0 0 193 262 1 1
    RHEB ZAP70 0 0 72 167 1 1
    RHEB PLK4 0 0 0 163 1 1
    RHEB STRADA 0 0 324 543 1 1
    RHEB RAB33B 0 0 61 173 1 2
    RHEB NPR1 0 0 0 169 1 1
    RHEB RAB40AL 0 0 450 338 1 1
    RHEB FGFR2 0 0 108 164 1 1
    RHEB ENO1 0 0 122 155 1 1
    RHEB PML 0 0 242 253 1 1
    RHEB ARHGAP12 0 0 66 159 1 1
    RHEB GAPDH 0 0 986 987 1 2
    RHEB LPAR5 0 0 0 152 1 1
    RHEB DUSP5 0 0 67 155 1 1
    RHEB PLEKHG6 0 0 0 160 1 1
    RHEB ARHGEF37 0 0 0 258 1 1
    RHEB ARL5B 0 0 122 155 1 1
    RHEB FKBP8 270 0 985 990 1 1
    RHEB SMG1 0 0 262 362 1 1
    RHEB PRR5 0 0 566 591 1 1
    RHEB TSSK3 0 0 0 154 1 1
    RHEB MAP2K7 0 0 459 503 1 1
    RHEB ABL1 0 0 150 237 1 1
    RHEB ESRRA 0 0 124 239 1 1
    RHEB TBC1D3B 0 0 0 156 1 1
    RHEB PFKFB3 0 0 181 181 1 1
    RHEB TPCN2 0 0 90 152 1 1
    RHEB RHOBTB2 0 0 96 216 1 1
    RHEB FIG4 0 0 67 186 1 1
    RHEB APC 0 0 114 162 1 1
    RHEB RAPGEF3 0 0 167 292 1 1
    RHEB CREB1 0 0 298 391 1 1
    RHEB RRN3 0 0 182 251 1 1
    RHEB RAB40B 0 0 0 236 1 1
    RHEB WASL 0 0 74 248 1 1
    RHEB INPPL1 0 0 124 206 1 1
    RHEB SLC38A9 0 600 606 851 1 1
    RHEB LAMTOR5 0 600 451 787 1 1
    RHEB RHOJ 0 0 95 167 1 1
    RHEB GRID2IP 0 0 0 251 1 1
    RHEB FNTB 0 0 51 330 1 1
    RHEB DIAPH1 0 0 0 160 1 1
    RHEB SIRT2 0 0 242 241 1 2
    RHEB AGAP2 0 0 70 183 1 1
    RHEB IQGAP1 0 0 67 256 1 1
    RHEB MAST3 0 0 0 189 1 1
    RHEB MFN1 0 0 155 210 1 1
    RHEB FRMPD4 0 0 0 154 1 1
    RHEB PUM2 0 0 0 158 1 1
    RHEB TMC7 0 0 88 287 1 1
    RHEB IRS2 0 0 401 419 1 1
    RHEB SLC36A2 0 0 120 176 1 1
    RHEB NEDD9 188 0 0 188 1 1
    RHEB WBSCR16 0 0 108 179 1 1
    RHEB ENSG00000270024 0 0 234 580 1 1
    RHEB MAST2 0 0 0 252 1 1
    RHEB PRKACB 0 0 0 252 1 1
    RHEB AGAP3 0 0 0 154 1 1
    RHEB PLCH2 0 0 0 194 1 1
    RHEB DHRS7B 0 0 0 175 1 1
    RHEB GRB2 0 0 323 373 1 1
    RHEB DOCK9 0 0 0 174 1 1
    RHEB LRIT1 0 0 0 154 1 1
    RHEB FYN 0 0 123 238 1 1
    RHEB ARHGAP11A 0 0 0 198 1 1
    RHEB ARNT 0 0 261 266 1 2
    RHEB SMC1A 0 0 0 168 1 1
    RHEB ARAP3 0 0 67 177 1 1
    RHEB SMC3 0 0 0 155 1 1
    RHEB SOD1 0 0 100 247 1 1
    RHEB TBC1D4 0 0 284 311 1 1
    RHEB FRMPD1 0 0 0 154 1 1
    RHEB GOLPH3L 0 0 0 161 1 1
    RHEB EPN2 0 0 0 275 1 1
    RHEB NPRL3 0 900 504 975 1 1
    RHEB CENPE 0 0 157 197 1 1
    RHEB ARHGEF16 0 0 0 160 1 1
    RHEB TRIM17 0 0 307 317 1 2
    RHEB RABEPK 0 0 0 202 1 1
    RHEB MTHFD2 0 0 148 170 1 1
    RHEB TRIO 0 0 0 187 1 1
    RHEB DPYSL2 0 0 150 223 1 1
    RHEB WDR31 0 0 0 164 1 1
    RHEB ENSG00000173366 0 0 56 161 1 1
    RHEB JUN 0 0 289 340 1 1
    RHEB ACSF2 0 0 53 227 1 1
    RHEB YKT6 0 0 74 189 1 1
    RHEB DAPK1 0 0 162 186 1 2
    RHEB TYK2 0 0 67 252 1 1
    RHEB MYO3A 0 0 0 170 1 1
    RHEB RASA4B 0 0 0 337 1 1
    RHEB EIF2AK1 0 0 153 152 1 1
    RHEB CCNA2 0 0 134 213 1 1
    RHEB EPN1 0 0 0 275 1 1
    RHEB ERBB4 0 0 151 275 1 1
    RHEB JAK3 0 0 123 227 1 1
    RHEB STXBP5 0 0 0 153 1 1
    RHEB PIK3CG 0 0 325 499 1 1
    RHEB ARHGDIA 0 0 182 366 1 1
    RHEB SLC7A3 0 0 0 153 1 1
    RHEB AP3B2 0 0 0 190 1 1
    RHEB MSN 0 0 134 202 1 1
    RHEB ENSG00000137843 0 0 0 229 1 1
    RHEB ATG13 0 600 564 883 1 2
    RHEB GNA14 0 0 0 177 1 1
    RHEB BNIP3 312 900 986 999 1 2
    RHEB SQSTM1 0 0 459 495 1 2
    RHEB JUNB 0 0 67 150 1 1
    RHEB STK38 0 0 0 184 1 1
    RHEB MMP9 0 0 150 172 1 1
    RHEB PSD4 0 0 0 154 1 1
    RHEB RND1 0 0 123 180 1 1
    RHEB KLF15 0 0 195 228 1 1
    RHEB MAPK3 0 0 452 587 1 2
    RHEB KLHDC1 0 0 0 176 1 1
    RHEB HSP90AA1 0 0 217 284 1 2
    RHEB PSEN1 0 0 123 172 1 2
    RHEB RAB29 0 0 127 173 1 1
    RHEB MUL1 0 0 138 150 1 2
    RHEB RHOV 0 0 81 165 1 1
    RHEB EPHA7 0 0 0 172 1 1
    RHEB DOCK10 0 0 0 174 1 1
    RHEB BCR 0 0 0 169 1 1
    RHEB RAB35 0 0 134 172 1 1
    RHEB ATP6V0B 0 600 0 616 1 1
    RHEB ENSG00000271810 0 0 0 156 1 1
    RHEB HUNK 0 0 0 154 1 1
    RHEB TBC1D28 0 0 0 156 1 1
    RHEB VPS16 0 0 57 164 1 1
    RHEB GNB1 0 0 46 174 1 1
    RHEB RALB 0 0 403 166 1 1
    RHEB MAP4K5 0 0 0 210 1 1
    RHEB ASAP3 0 0 53 182 1 1
    RHEB AR 0 0 172 263 1 1
    RHEB ECT2 0 0 45 165 1 1
    RHEB HNRNPH1 270 0 46 292 1 1
    RHEB ATG9A 0 0 181 349 1 2
    RHEB CSF2RA 0 0 166 165 1 1
    RHEB CDKN1A 0 0 207 236 1 2
    RHEB GNA12 0 0 0 213 1 1
    RHEB KLHDC10 0 0 0 176 1 1
    RHEB PLXNA1 0 0 0 163 1 1
    RHEB MIP 0 0 0 207 1 1
    RHEB SLC38A2 0 0 323 337 1 1
    RHEB EIF5 0 0 134 184 1 1
    RHEB STX4 0 0 54 251 1 1
    RHEB MICAL2 0 0 0 163 1 1
    RHEB EPHA4 0 0 73 255 1 1
    RHEB ASL 0 0 0 154 1 1
    RHEB SGK494 0 0 0 391 1 1
    RHEB FKBP4 0 0 90 248 1 1
    RHEB PDE4D 0 0 956 962 1 1
    RHEB SIRT6 0 0 217 217 1 1
    RHEB PGGT1B 0 0 122 258 1 1
    RHEB VPS35 0 0 54 202 1 1
    RHEB PDGFRA 0 0 125 180 1 1
    RHEB CDK16 0 0 0 269 1 1
    RHEB MIOS 0 900 459 967 1 1
    RHEB RIC1 0 0 0 249 1 1
    RHEB ZCCHC14 0 0 0 176 1 1
    RHEB ADAP1 0 0 0 172 1 1
    RHEB RAB32 0 0 45 458 1 2
    RHEB SH3PXD2A 0 0 0 160 1 1
    RHEB PRKCZ 0 0 193 302 1 1
    RHEB CDH1 0 0 170 183 1 1
    RHEB NCF4 0 0 46 261 1 1
    RHEB DAAM1 0 0 0 204 1 1
    RHEB TBC1D2 0 0 0 173 1 1
    RHEB MAP3K11 0 0 74 172 1 1
    RHEB ZNF365 0 0 51 195 1 1
    RHEB PDE4A 0 0 70 200 1 1
    RHEB RBM19 0 0 60 150 1 1
    RHEB ACVR2B 0 0 61 157 1 1
    RHEB MAGI3 0 0 50 174 1 1
    RHEB MAP1B 0 0 96 185 1 1
    RHEB PIK3AP1 0 0 0 167 1 1
    RHEB WNT1 0 0 89 235 1 1
    RHEB ALK 0 0 170 270 1 1
    RHEB ROCK2 0 0 57 166 1 1
    RHEB EIF4A1 0 0 391 479 1 1
    RHEB BBS7 0 0 0 163 1 1
    RHEB ALB 0 0 253 299 1 1
    RHEB SGK2 0 0 0 463 1 1
    RHEB GNB2 0 0 0 194 1 1
    RHEB ELAVL1 0 0 203 209 1 1
    RHEB RAP1GAP2 0 0 52 151 1 1
    RHEB CASP7 0 0 122 192 1 1
    RHEB EP300 0 0 180 219 1 1
    RHEB AGMAT 0 0 48 174 1 1
    RHEB NUMB 0 0 71 184 1 1
    RHEB PDGFRB 0 0 141 228 1 1
    RHEB SH3PXD2B 0 0 0 160 1 1
    RHEB AP1M1 0 0 0 330 1 1
    RHEB HKDC1 0 0 0 162 1 1
    RHEB IL4 0 0 181 265 1 1
    RHEB WNT9B 0 0 66 171 1 1
    RHEB ENSG00000267318 0 0 0 191 1 1
    RHEB SMAD3 0 0 154 172 1 1
    RHEB ROCK1 0 0 150 262 1 1
    RHEB RAPH1 0 0 51 155 1 1
    RHEB RABGAP1L 0 0 0 176 1 1
    RHEB FLCN 0 0 557 755 1 1
    RHEB SLC1A2 0 0 96 293 1 1
    RHEB HTR6 0 0 0 181 1 1
    RHEB TRAF6 0 0 234 277 1 2
    RHEB SESN3 0 0 369 531 1 1
    RHEB DGKZ 0 0 170 169 1 1
    RHEB CYCS 0 0 242 279 1 1
    RHEB DUSP12 0 0 53 174 1 1
    RHEB RGL2 0 0 115 289 1 1
    RHEB CAMKK1 0 0 62 173 1 1
    RHEB APPL2 0 0 0 183 1 1
    RHEB RAC3 0 0 74 200 1 1
    RHEB EPS15L1 0 0 0 178 1 1
    RHEB GNAZ 0 0 0 213 1 1
    RHEB SH3GLB1 0 0 241 240 1 2
    RHEB EGF 0 0 325 325 1 1
    RHEB DOCK11 0 0 0 174 1 1
    RHEB GAK 0 0 0 229 1 1
    RHEB TIAM2 0 0 0 289 1 1
    RHEB GATA4 0 0 74 153 1 2
    RHEB HSPA4 0 0 171 222 1 1
    RHEB PIK3R1 0 0 380 422 1 1
    RHEB CLTC 0 0 46 215 1 1
    RHEB DICER1 0 0 156 205 1 1
    RHEB PDCD4 0 0 241 288 1 1
    RHEB TUBD1 0 0 0 155 1 1
    RHEB RABGGTB 0 0 0 185 1 1
    RHEB PDE6B 0 0 66 197 1 1
    RHEB ATP6V1D 0 600 89 648 1 1
    RHEB TRIM55 192 0 0 204 1 1
    RHEB PPARA 0 0 213 299 1 1
    RHEB ARHGDIB 0 0 0 252 1 1
    RHEB SESN2 0 900 517 962 1 2
    RHEB ENSG00000249319 0 0 0 161 1 1
    RHEB ARHGEF3 0 0 90 226 1 1
    RHEB RASA4 0 0 0 337 1 1
    RHEB TDP2 0 0 141 189 1 1
    RHEB VPS52 0 0 0 174 1 1
    RHEB TRAPPC10 0 0 0 233 1 1
    RHEB EIF2S2 0 0 74 199 1 1
    RHEB RAB6A 0 0 133 279 1 1
    RHEB PEX5 0 0 166 171 1 1
    RHEB MAPK8 0 0 281 348 1 2
    RHEB RAB43 0 0 0 214 1 1
    RHEB BRAF 213 0 92 400 1 1
    RHEB ATP6V0D2 0 600 0 781 1 1
    RHEB PRKAR1B 0 0 0 251 1 1
    RHEB AKAP13 0 0 0 160 1 1
    RHEB API5 0 0 0 166 1 1
    RHEB PLD1 270 0 885 941 1 1
    RHEB MAGOHB 0 0 114 171 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0019003 Molecular Function GDP binding enables IBA
    GO:0019003 Molecular Function GDP binding enables IMP
    GO:0005525 Molecular Function GTP binding enables IBA
    GO:0005525 Molecular Function GTP binding enables IMP
    GO:0005525 Molecular Function GTP binding enables ISS
    GO:0003924 Molecular Function GTPase activity enables IBA
    GO:0003924 Molecular Function GTPase activity enables IDA
    GO:0003924 Molecular Function GTPase activity enables TAS
    GO:0000287 Molecular Function magnesium ion binding enables IMP
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0030295 Molecular Function protein kinase activator activity enables IDA
    GO:0019901 Molecular Function protein kinase binding enables IEA
    GO:0043539 Molecular Function protein serine/threonine kinase activator activity enables IDA
    GO:0031669 Biological Process cellular response to nutrient levels involved_in IDA
    GO:0120163 Biological Process negative regulation of cold-induced thermogenesis involved_in ISS
    GO:0048709 Biological Process oligodendrocyte differentiation involved_in IEA
    GO:0032008 Biological Process positive regulation of TOR signaling involved_in IMP
    GO:1904263 Biological Process positive regulation of TORC1 signaling involved_in IDA
    GO:0048714 Biological Process positive regulation of oligodendrocyte differentiation involved_in IEA
    GO:0051726 Biological Process regulation of cell cycle involved_in TAS
    GO:0016241 Biological Process regulation of macroautophagy involved_in TAS
    GO:2000074 Biological Process regulation of type B pancreatic cell development involved_in IMP
    GO:0007165 Biological Process signal transduction involved_in TAS
    GO:0007264 Biological Process small GTPase-mediated signal transduction involved_in IBA
    GO:0000139 Cellular Component Golgi membrane located_in IEA
    GO:0005829 Cellular Component cytosol located_in IEA
    GO:0012505 Cellular Component endomembrane system is_active_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IEA
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005765 Cellular Component lysosomal membrane is_active_in IDA
    GO:0005765 Cellular Component lysosomal membrane located_in TAS
    GO:0016020 Cellular Component membrane located_in TAS
    GO:0005886 Cellular Component plasma membrane is_active_in IBA
    GO:0014069 Cellular Component postsynaptic density is_active_in EXP
    GO:0014069 Cellular Component postsynaptic density is_active_in IDA
    GO:0005681 Cellular Component spliceosomal complex part_of IEA
    Pathways
    Name DB ID
    PIP3 activates AKT signaling Reactome R-HSA-1257604
    Signal Transduction Reactome R-HSA-162582
    Macroautophagy Reactome R-HSA-1632852
    MTOR signalling Reactome R-HSA-165159
    mTORC1-mediated signalling Reactome R-HSA-166208
    Generic Transcription Pathway Reactome R-HSA-212436
    Cellular responses to stress Reactome R-HSA-2262752
    Transcriptional Regulation by TP53 Reactome R-HSA-3700989
    Energy dependent regulation of mTOR by LKB1-AMPK Reactome R-HSA-380972
    TP53 Regulates Metabolic Genes Reactome R-HSA-5628897
    PTEN Regulation Reactome R-HSA-6807070
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Gene expression (Transcription) Reactome R-HSA-74160
    Regulation of PTEN gene transcription Reactome R-HSA-8943724
    Cellular responses to stimuli Reactome R-HSA-8953897
    Intracellular signaling by second messengers Reactome R-HSA-9006925
    Autophagy Reactome R-HSA-9612973
    Amino acids regulate mTORC1 Reactome R-HSA-9639288
    Cellular response to starvation Reactome R-HSA-9711097
    Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
    Thermogenesis (WP4321) WikiPathways WP4321_r123362
    Joubert syndrome (WP4656) WikiPathways WP4656_r120396
    Fragile X syndrome (WP4549) WikiPathways WP4549_r124287
    Thyroid hormones production and peripheral downstream signaling effects (WP4746) WikiPathways WP4746_r123317
    Clear cell renal cell carcinoma pathways (WP4018) WikiPathways WP4018_r123404
    PI3K-AKT-mTOR signaling pathway and therapeutic opportunities (WP3844) WikiPathways WP3844_r107714
    Follicle stimulating hormone (FSH) signaling pathway (WP2035) WikiPathways WP2035_r120721
    Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
    Insulin signaling (WP481) WikiPathways WP481_r120562
    BDNF-TrkB signaling (WP3676) WikiPathways WP3676_r116809
    Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway (WP4577) WikiPathways WP4577_r123500
    Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
    Synaptic signaling pathways associated with autism spectrum disorder (WP4539) WikiPathways WP4539_r113659
    Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
    PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
    T-cell activation SARS-CoV-2 (WP5098) WikiPathways WP5098_r119538
    Angiopoietin-like protein 8 regulatory pathway (WP3915) WikiPathways WP3915_r123920
    Target of rapamycin signaling (WP1471) WikiPathways WP1471_r123616
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_005614 4 mRNA None NC_000007 Reference
    XM_011516457 3 mRNA transcript variant X1 NC_000007 Reference
    XM_024446854 2 mRNA transcript variant X2 NC_000007 Reference
    XM_047420685 1 mRNA transcript variant X3 NC_000007 Reference