BCL2

BCL2 apoptosis regulator
General Information
Name BCL2 apoptosis regulator
Alias
  • apoptosis regulator Bcl-2
  • B-cell CLL/lymphoma 2
  • protein phosphatase 1, regulatory subunit 50
Synonyms Bcl-2 PPP1R50
Gene_family Protein phosphatase 1 regulatory subunits|BCL2 family
organism Homo sapiens
entrez_id 596
location 18q21.33
transcript_count 6
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
      Stringdb Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release; BCL2 family
      nextProt Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells (PubMed:1508712, PubMed:8183370). Regulates cell death by controlling the mitochondrial membrane permeability (PubMed:11368354). Appears to function in a feedback loop system with caspases (PubMed:11368354). Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) (PubMed:11368354). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function (PubMed:18570871, PubMed:21358617, PubMed:20889974). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    BCL2 BioGRID NCL GeneID BioGRID Protein-RNA
    BCL2 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID HIF1A GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID HNRNPD GeneID BioGRID Affinity Capture-RNA; Two-hybrid
    BCL2 BioGRID BECN1 GeneID BioGRID Affinity Capture-Western; Co-purification; FRET; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID BRCA2 GeneID BioGRID Positive Genetic
    BCL2 BioGRID TOMM20 GeneID BioGRID Co-localization; Reconstituted Complex
    BCL2 BioGRID BCL2L10 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PRUNE2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID SIVA1 GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID NR3C1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID BRD4 GeneID BioGRID Co-localization
    BCL2 BioGRID POLR2A GeneID BioGRID Co-localization
    BCL2 BioGRID CDK9 GeneID BioGRID Co-localization
    BCL2 BioGRID BBC3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide
    BCL2 BioGRID GHITM GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID FKBP8 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID ANKLE2 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID BCL2L11 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID MTMR4 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID PKMYT1 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID PEX3 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID TMBIM6 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    BCL2 BioGRID TAP1 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID RGPD2 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID XXYLT1 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID ACBD5 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID TMEM259 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID MFF GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID GALNT10 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID ABCB1 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID MTHFR GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID BIK GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Two-hybrid
    BCL2 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Reconstituted Complex
    BCL2 BioGRID BAX GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID BAD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptide; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID ABCD1 GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
    BCL2 BioGRID PRKN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID BCAP31 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-purification; Protein-peptide; Reconstituted Complex
    BCL2 BioGRID BAK1 GeneID BioGRID Affinity Capture-Western; Protein-peptide
    BCL2 BioGRID LDLR GeneID BioGRID Positive Genetic
    BCL2 BioGRID ACACA GeneID BioGRID Positive Genetic
    BCL2 BioGRID SREBF2 GeneID BioGRID Positive Genetic
    BCL2 BioGRID SPHK2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID FAIM2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID LRPPRC GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID ITPR3 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CDK2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CUL4A GeneID BioGRID Affinity Capture-MS
    BCL2 BioGRID PSEN2 GeneID BioGRID Affinity Capture-Western; Co-localization
    BCL2 BioGRID PSEN1 GeneID BioGRID Affinity Capture-Western; Co-localization; Two-hybrid
    BCL2 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
    BCL2 BioGRID KEAP1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID RNF183 GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID BCL2L12 GeneID BioGRID Two-hybrid
    BCL2 BioGRID TNIP2 GeneID BioGRID Affinity Capture-RNA
    BCL2 BioGRID SEPTIN4 GeneID BioGRID Affinity Capture-Western; PCA; Protein-peptide
    BCL2 BioGRID XIAP GeneID BioGRID Biochemical Activity; Reconstituted Complex
    BCL2 BioGRID RTN4 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID RTN3 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CDK4 GeneID BioGRID Negative Genetic
    BCL2 BioGRID BARD1 GeneID BioGRID Co-localization
    BCL2 BioGRID MAT2A GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID UBE2I GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPARA GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    BCL2 BioGRID PPP2CA GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    BCL2 BioGRID BNIP3L GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID MAPK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    BCL2 BioGRID BMF GeneID BioGRID Affinity Capture-Western; Protein-peptide
    BCL2 BioGRID BID GeneID BioGRID Affinity Capture-Western; Co-fractionation; Protein-peptide; Reconstituted Complex
    BCL2 BioGRID Bax GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID GIMAP5 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID NMT2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPP3CA GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID VDAC1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID ITPR1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID CASP8 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression; Two-hybrid
    BCL2 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID TP53BP2 GeneID BioGRID Protein-peptide; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID ATP2A3 GeneID BioGRID Affinity Capture-Luminescence
    BCL2 BioGRID NR4A1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID KRAS GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPID GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID MDM4 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID BNIP3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID BFAR GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID CDK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    BCL2 BioGRID BAG3 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID RAF1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID IKBKG GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPP3CC GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID MAPK8 GeneID BioGRID Biochemical Activity
    BCL2 BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CRYAB GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CHUK GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PML GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID BRCA1 GeneID BioGRID Affinity Capture-Western; FRET
    BCL2 BioGRID AMBRA1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID ATG12 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID CISD2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID MEX3D GeneID BioGRID Two-hybrid
    BCL2 BioGRID PPP1CC GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPP1CB GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPP1CA GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID ITLN1 GeneID BioGRID Dosage Rescue
    BCL2 BioGRID BLID GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID gag-pol GeneID BioGRID Biochemical Activity
    BCL2 Protein MOAP1 GeneID HPRD None
    BCL2 Protein BNIPL GeneID HPRD None
    BCL2 Protein BFAR GeneID HPRD None
    BCL2 Protein BCLAF1 GeneID HPRD None
    BCL2 Protein BBC3 GeneID HPRD None
    BCL2 Protein PPP1CA GeneID HPRD None
    BCL2 Protein PMAIP1 GeneID HPRD None
    BCL2 Protein NMT2 GeneID HPRD None
    BCL2 Protein TP53BP2 GeneID HPRD None
    BCL2 Protein SPNS1 GeneID HPRD None
    BCL2 Protein TP53AIP1 GeneID HPRD None
    BCL2 Protein PPP2CA GeneID HPRD None
    BCL2 Protein NLRP1 GeneID HPRD None
    BCL2 Protein BNIP3L GeneID HPRD None
    BCL2 Protein RTN4 GeneID HPRD None
    BCL2 Protein BCL2L10 GeneID HPRD None
    BCL2 Protein BMF GeneID HPRD None
    BCL2 Protein BCL2L14 GeneID HPRD None
    BCL2 Protein FKBP8 GeneID HPRD None
    BCL2 Protein BECN1 GeneID HPRD None
    BCL2 Protein ITM2B GeneID HPRD None
    BCL2 Protein BAG4 GeneID HPRD None
    BCL2 Protein BAG3 GeneID HPRD None
    BCL2 Protein BCL2L11 GeneID HPRD None
    BCL2 Protein RAD9A GeneID HPRD None
    BCL2 Protein HRK GeneID HPRD None
    BCL2 Protein BIK GeneID HPRD None
    BCL2 Protein BNIP3 GeneID HPRD None
    BCL2 Protein BNIP2 GeneID HPRD None
    BCL2 Protein BNIP1 GeneID HPRD None
    BCL2 Protein BAD GeneID HPRD None
    BCL2 Protein MAPK11 GeneID HPRD None
    BCL2 Protein PXN GeneID HPRD None
    BCL2 Protein PKMYT1 GeneID HPRD None
    BCL2 Protein BID GeneID HPRD None
    BCL2 Protein TOMM20 GeneID HPRD None
    BCL2 Protein MAPK3 GeneID HPRD None
    BCL2 Protein CASP8 GeneID HPRD None
    BCL2 Protein PPP2R5A GeneID HPRD None
    BCL2 Protein PRKACA GeneID HPRD None
    BCL2 Protein SF1 GeneID HPRD None
    BCL2 Protein BAG1 GeneID HPRD None
    BCL2 Protein MAPK8 GeneID HPRD None
    BCL2 Protein PIN1 GeneID HPRD None
    BCL2 Protein TMBIM6 GeneID HPRD None
    BCL2 Protein CASP3 GeneID HPRD None
    BCL2 Protein CPT1A GeneID HPRD None
    BCL2 Protein BAK1 GeneID HPRD None
    BCL2 Protein SMN2 GeneID HPRD None
    BCL2 Protein MAPK14 GeneID HPRD None
    BCL2 Protein BAX GeneID HPRD None
    BCL2 Protein BCL2L1 GeneID HPRD None
    BCL2 Protein BCAP31 GeneID HPRD None
    BCL2 Protein BLK GeneID HPRD None
    BCL2 Protein TP53 GeneID HPRD None
    BCL2 Protein MYC GeneID HPRD None
    BCL2 Protein KRAS GeneID HPRD None
    BCL2 Protein HRAS GeneID HPRD None
    BCL2 Protein PRKCA GeneID HPRD None
    BCL2 Protein MAPK1 GeneID HPRD None
    BCL2 Protein PARP1 GeneID HPRD None
    BCL2 Protein RRAS GeneID HPRD None
    BCL2 Protein NRAS GeneID HPRD None
    BCL2 Protein RAF1 GeneID HPRD None
    BCL2 Protein BCL2 GeneID HPRD None
    BCL2 Protein SOD1 GeneID HPRD None
    BCL2 Protein ITPR1 GeneID HPRD None
    BCL2 Protein HSPA1A GeneID HPRD None
    BCL2 Protein NR4A1 GeneID HPRD None
    BCL2 Protein CYCS GeneID HPRD None
    BCL2 Protein CDK2 GeneID HPRD None
    BCL2 Protein PPP3CA GeneID HPRD None
    BCL2 Protein ATP2A2 GeneID HPRD None
    BCL2 Protein PSEN1 GeneID HPRD None
    BCL2 Protein PML GeneID HPRD None
    BCL2 BioGRID RAD9A GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID CASP3 GeneID BioGRID Biochemical Activity
    BCL2 BioGRID BNIP2 GeneID BioGRID Reconstituted Complex; Two-hybrid
    BCL2 BioGRID BNIP1 GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID BAG1 GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID PARP1 GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID HRK GeneID BioGRID Affinity Capture-Western; Protein-peptide; Two-hybrid
    BCL2 BioGRID SMN1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID PMAIP1 GeneID BioGRID Affinity Capture-Western; Protein-peptide
    BCL2 BioGRID DYNLL1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID Bcl2l11 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Two-hybrid
    BCL2 BioGRID CASP2 GeneID BioGRID Phenotypic Suppression
    BCL2 BioGRID IRS2 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PPP2R5A GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID PIN1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID IRS1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID HSPA1A GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID BLK GeneID BioGRID Reconstituted Complex
    BCL2 BioGRID ITM2B GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID BNIPL GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    BCL2 BioGRID MOAP1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID AVEN GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID TP53AIP1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID RRAS GeneID BioGRID Affinity Capture-Western; Two-hybrid
    BCL2 BioGRID CAPN2 GeneID BioGRID Biochemical Activity; Reconstituted Complex
    BCL2 BioGRID Becn1 GeneID BioGRID Two-hybrid
    BCL2 BioGRID SPNS1 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID SOD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    BCL2 BioGRID SERPINB8 GeneID BioGRID Affinity Capture-Western
    BCL2 BioGRID MYC GeneID BioGRID Affinity Capture-Western; Co-localization
    BCL2 None None None BIND RTN-XS interacts with Bcl-2.
    BCL2 Protein MOAP1 GeneID BIND MAP-1 interacts with Bcl-2.
    BCL2 Protein BIK GeneID BIND Bik interacts with Bcl-2.
    BCL2 Protein BCL2L11 GeneID BIND Bim interacts with Bcl-2.
    BCL2 Protein BBC3 GeneID BIND Puma interacts with Bcl-2.
    BCL2 Protein BAD GeneID BIND Bad interacts with Bcl-2.
    BCL2 Protein HRK GeneID BIND Hrk interacts with Bcl-2.
    BCL2 Protein BID GeneID BIND Bid interacts with Bcl-2.
    BCL2 Protein BMF GeneID BIND Bmf interacts with Bcl-2. This interaction was modelled on a demonstrated interaction between mouse Bmf and human Bcl-2.
    BCL2 None None None BIND Bad interacts with Bcl-2.
    BCL2 None None None BIND PUMA interacts with Bcl-2.
    BCL2 None None None BIND Bax interacts with Bcl-2.
    BCL2 None None None BIND Bid interacts with Bcl-2.
    BCL2 None None None BIND Bcl-2 interacts with BAG-4. This interaction was modelled on a demonstrated interaction between Bcl-2 from an unspecified species and human BAG-4.
    BCL2 None None None BIND Bcl-2 interacts with BAG-3. This interaction was modelled on a demonstrated interaction between Bcl-2 from an unspecified species and human BAG-3.
    BCL2 Nucleotide None None BIND The RAG complex interacts with the major breakpoint region (Mbr) of the Bcl-2 gene. This interaction was modelled on a demonstrated interaction between RAG complex from mouse and the human Bcl-2 gene.
    BCL2 Protein BNIPL GeneID BIND BNIPL-2 interacts with Bcl-2.
    BCL2 None None None BIND PUMA-beta interacts with Bcl-2.
    BCL2 None None None BIND PUMA-alpha interacts with Bcl-2.
    BCL2 Protein BAX GeneID BIND Bcl-2 interacts with Bax.
    BCL2 Protein BIK GeneID BIND Bcl-2 interacts with Bik.
    BCL2 Protein RHEB GeneID BIND Bcl-2 interacts with Rheb.
    BCL2 Protein HRK GeneID BIND Hrk interacts with Bcl-2.
    BCL2 Protein BAD GeneID BIND Bcl-2 interacts with Bad.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    BCL2 MMP2 0 0 166 165 1 1
    BCL2 MAT2A 270 0 66 289 1 1
    BCL2 PRKACB 0 900 0 900 1 1
    BCL2 TM9SF4 0 0 0 206 1 1
    BCL2 BASP1 0 0 55 168 1 1
    BCL2 CRK 0 0 0 156 1 1
    BCL2 CD8A 0 0 134 153 1 1
    BCL2 SEPT4 270 0 0 285 1 1
    BCL2 IRS2 270 0 74 295 1 1
    BCL2 BIK 880 900 283 990 1 1
    BCL2 CALR 282 0 74 311 1 1
    BCL2 SMAD1 0 0 134 153 1 1
    BCL2 MFN1 0 0 113 353 1 1
    BCL2 RSAD1 0 0 59 197 1 1
    BCL2 HIST1H2BK 0 900 0 900 1 1
    BCL2 EPN2 0 0 0 183 1 1
    BCL2 B3GNT9 0 0 201 216 1 1
    BCL2 PIGC 0 0 0 256 1 1
    BCL2 SHH 0 0 134 157 1 1
    BCL2 LTA 0 0 63 199 1 1
    BCL2 SOD1 297 800 135 870 1 1
    BCL2 CABLES1 0 0 0 233 1 1
    BCL2 CAPN2 270 0 0 270 1 2
    BCL2 CTSF 0 600 0 609 1 1
    BCL2 NFKBIE 0 0 74 166 1 1
    BCL2 TICAM1 0 0 44 221 1 1
    BCL2 RTN1 0 0 0 169 1 1
    BCL2 DAPK1 0 0 120 154 1 2
    BCL2 JUN 0 0 270 286 1 1
    BCL2 ITPR3 270 0 134 342 1 1
    BCL2 SEPHS1 0 0 0 190 1 1
    BCL2 BCL2L11 913 800 510 992 1 1
    BCL2 APIP 0 0 108 174 1 1
    BCL2 MEX3D 192 0 0 192 1 1
    BCL2 BOK 0 0 273 273 1 2
    BCL2 JAK3 0 900 45 900 1 1
    BCL2 VRK2 192 0 0 198 1 1
    BCL2 PIK3CG 0 0 226 268 1 1
    BCL2 EPN1 0 0 0 183 1 1
    BCL2 TNFSF10 0 0 181 181 1 2
    BCL2 HSPA1A 270 0 91 321 1 1
    BCL2 CASP1 0 0 176 332 1 2
    BCL2 AKT1S1 0 0 90 204 1 1
    BCL2 DNTT 0 0 264 264 1 1
    BCL2 KEAP1 270 0 107 328 1 2
    BCL2 MMP9 0 0 193 209 1 1
    BCL2 MAPK3 213 900 297 939 1 2
    BCL2 SQSTM1 486 0 166 562 1 2
    BCL2 BNIP3 732 800 465 970 1 2
    BCL2 TFAP2D 0 0 0 216 1 1
    BCL2 ANXA4 0 0 0 189 1 1
    BCL2 FOXG1 0 0 0 152 1 1
    BCL2 INS 0 0 194 204 1 1
    BCL2 ACTB 0 0 325 351 1 1
    BCL2 GOT1 0 0 0 212 1 1
    BCL2 SPG7 0 720 0 720 1 1
    BCL2 HTRA2 0 0 181 198 1 1
    BCL2 CEBPA 270 0 67 289 1 1
    BCL2 COX4I1 0 0 134 187 1 1
    BCL2 PSEN1 486 0 75 547 1 2
    BCL2 ATF2 0 0 92 217 1 1
    BCL2 HSP90AA1 486 0 161 550 1 2
    BCL2 BCL3 0 0 85 161 1 1
    BCL2 ZEB1 0 0 123 163 1 1
    BCL2 GABARAPL1 0 0 96 152 1 2
    BCL2 BCL2L12 192 0 101 248 1 1
    BCL2 ESR2 0 0 170 183 1 1
    BCL2 DUSP16 0 0 0 159 1 1
    BCL2 IMMP2L 0 0 66 381 1 1
    BCL2 TOMM40 0 540 93 564 1 1
    BCL2 HIST1H2BL 0 900 0 900 1 1
    BCL2 BAX 981 900 758 998 1 2
    BCL2 BCLAF1 462 0 0 461 1 1
    BCL2 CDKN1A 0 0 299 299 1 2
    BCL2 PARP1 270 0 210 443 1 2
    BCL2 AR 0 0 161 174 1 1
    BCL2 BID 870 800 507 989 1 1
    BCL2 TCTN1 0 0 66 163 1 1
    BCL2 CDH1 0 0 156 180 1 1
    BCL2 BCL2L10 270 0 169 367 1 1
    BCL2 C8B 0 720 0 727 1 1
    BCL2 DUSP8 0 0 63 178 1 1
    BCL2 TTLL1 0 0 0 153 1 1
    BCL2 CDK6 0 0 203 225 1 1
    BCL2 CTH 0 0 53 158 1 1
    BCL2 HIST1H2BO 0 900 0 900 1 1
    BCL2 TRADD 0 0 203 209 1 1
    BCL2 PPP1CB 128 0 0 179 1 1
    BCL2 DNM2 0 0 67 299 1 1
    BCL2 ACTR1B 0 0 0 158 1 1
    BCL2 MAP1B 0 0 74 156 1 1
    BCL2 PPP2R5A 270 600 0 695 1 1
    BCL2 EIF2B4 0 0 0 302 1 1
    BCL2 ZCCHC3 0 0 0 216 1 1
    BCL2 CASP7 0 0 218 387 1 1
    BCL2 BCL9 0 0 107 244 1 1
    BCL2 ITLN1 209 0 0 209 1 1
    BCL2 ALB 0 0 182 200 1 1
    BCL2 CASP8 681 0 395 838 1 2
    BCL2 PPP2R1B 0 600 52 604 1 1
    BCL2 NAPB 0 0 0 154 1 1
    BCL2 CARD17 0 0 0 200 1 1
    BCL2 CHRAC1 0 0 0 155 1 1
    BCL2 TP53AIP1 270 0 0 270 1 1
    BCL2 MLLT4 0 720 0 720 1 1
    BCL2 TNFRSF10A 0 0 166 166 1 1
    BCL2 RNF183 270 0 0 281 1 1
    BCL2 BIRC3 0 0 186 218 1 1
    BCL2 SMAD3 0 0 143 187 1 1
    BCL2 PRMT3 0 0 0 160 1 1
    BCL2 EP300 0 900 134 909 1 1
    BCL2 SLC30A1 0 0 45 166 1 1
    BCL2 CDK5 0 0 72 216 1 2
    BCL2 BFAR 270 0 107 327 1 1
    BCL2 PRKAB2 0 0 48 308 1 1
    BCL2 EGF 0 0 170 169 1 1
    BCL2 CYCS 213 900 605 967 1 1
    BCL2 MAPK9 0 800 75 813 1 2
    BCL2 CASP9 0 0 457 581 1 1
    BCL2 ITPR1 486 0 136 555 1 2
    BCL2 ANXA13 0 0 0 252 1 1
    BCL2 PPARA 270 0 75 307 1 1
    BCL2 IER3 270 0 55 280 1 1
    BCL2 RPTOR 0 0 113 269 1 2
    BCL2 PDCD4 0 0 260 260 1 1
    BCL2 MYCL 0 0 218 218 1 1
    BCL2 PIK3R1 0 0 109 162 1 1
    BCL2 DICER1 0 0 143 178 1 1
    BCL2 CTSH 0 600 0 613 1 1
    BCL2 HSPA4 0 0 180 179 1 1
    BCL2 C9 0 720 0 720 1 1
    BCL2 MX2 0 0 54 246 1 1
    BCL2 NR3C1 0 0 105 239 1 1
    BCL2 IL2RG 0 900 0 908 1 1
    BCL2 PPP2CB 0 600 0 612 1 1
    BCL2 PRNP 0 900 0 909 1 1
    BCL2 P2RX7 0 0 52 326 1 1
    BCL2 GRINA 0 0 0 160 1 1
    BCL2 PPP2R5B 0 600 0 600 1 1
    BCL2 DIABLO 0 900 315 932 1 1
    BCL2 PXN 213 0 0 352 1 1
    BCL2 TFF1 0 0 117 208 1 1
    BCL2 TNS1 0 0 145 176 1 1
    BCL2 PAK2 0 0 142 195 1 1
    BCL2 MAP2K4 0 0 146 169 1 1
    BCL2 BRAF 0 0 207 207 1 1
    BCL2 ATP6V0D2 0 0 0 181 1 1
    BCL2 PRKAR1B 0 900 60 904 1 1
    BCL2 MAPK8 463 900 258 957 1 2
    BCL2 PRKAB1 0 0 44 433 1 2
    BCL2 PTK2 0 0 66 203 1 1
    BCL2 HIST1H2BH 0 900 0 900 1 1
    BCL2 BLID 270 0 134 340 1 1
    BCL2 MOAP1 270 0 0 270 1 1
    BCL2 CASP10 0 0 142 310 1 1
    BCL2 NCKAP1L 0 0 0 150 1 1
    BCL2 PPP3CC 270 0 0 346 1 1
    BCL2 MAP2K1 0 0 170 396 1 1
    BCL2 PPIF 192 720 124 809 1 1
    BCL2 HIST1H2BM 0 900 0 900 1 1
    BCL2 OPA1 0 0 66 339 1 1
    BCL2 IKZF3 0 900 0 901 1 1
    BCL2 MFF 0 0 95 196 1 1
    BCL2 C5 0 720 0 720 1 1
    BCL2 BRCA1 271 0 161 362 1 1
    BCL2 STK11 0 0 113 270 1 2
    BCL2 CTSV 0 600 53 608 1 1
    BCL2 SPEG 0 0 0 188 1 1
    BCL2 AKT2 0 800 193 834 1 1
    BCL2 RB1CC1 0 0 125 220 1 2
    BCL2 NEGR1 0 0 57 469 1 1
    BCL2 NFE2L2 0 0 160 159 1 1
    BCL2 ADAM10 0 720 0 720 1 1
    BCL2 HIST1H2BD 0 900 0 900 1 1
    BCL2 IGF1R 0 0 212 212 1 1
    BCL2 PARK2 270 0 82 382 1 1
    BCL2 WNT5A 0 0 0 416 1 1
    BCL2 STEAP3 0 0 0 150 1 1
    BCL2 RALGDS 0 0 63 152 1 1
    BCL2 PDK1 0 0 134 152 1 1
    BCL2 MYC 270 0 380 584 1 2
    BCL2 NR4A3 270 0 0 284 1 1
    BCL2 PIK3CA 0 0 181 214 1 2
    BCL2 ATRAID 0 0 0 303 1 1
    BCL2 TRAF2 0 0 218 218 1 1
    BCL2 SLC7A1 0 0 0 260 1 1
    BCL2 TMBIM6 270 0 142 346 1 1
    BCL2 MX1 0 0 74 262 1 1
    BCL2 PIM1 0 0 213 213 1 1
    BCL2 PPARD 0 0 48 158 1 1
    BCL2 NR4A1 695 900 397 980 1 1
    BCL2 CISD2 270 0 0 320 1 2
    BCL2 PIN1 462 0 118 517 1 1
    BCL2 CAMKK2 0 0 431 431 1 2
    BCL2 CTSW 0 600 0 604 1 1
    BCL2 BRD4 270 0 0 270 1 1
    BCL2 RAD9A 486 0 0 592 1 1
    BCL2 APAF1 0 900 413 973 1 1
    BCL2 JAK2 0 0 180 205 1 1
    BCL2 WNT5B 0 0 67 482 1 1
    BCL2 VDAC2 0 540 204 647 1 1
    BCL2 ATP6V0D1 0 0 0 158 1 1
    BCL2 STAT3 0 900 261 936 1 2
    BCL2 EZH2 0 0 160 159 1 1
    BCL2 MYH6 0 0 67 165 1 1
    BCL2 PRKAR2A 0 900 0 903 1 1
    BCL2 DYNLL1 270 0 141 346 1 1
    BCL2 SIVA1 270 800 0 854 1 1
    BCL2 PCSK5 0 0 0 155 1 1
    BCL2 PPP1CC 128 0 0 235 1 1
    BCL2 MYD88 0 0 123 251 1 1
    BCL2 EGFR 0 0 320 319 1 1
    BCL2 CFLAR 0 0 234 361 1 1
    BCL2 CDK4 217 0 218 397 1 1
    BCL2 FADD 0 0 218 242 1 2
    BCL2 BNIP2 680 0 81 697 1 1
    BCL2 MDM2 0 0 283 373 1 1
    BCL2 TP53 870 900 612 995 1 2
    BCL2 CRADD 0 0 181 181 1 1
    BCL2 PRKACG 0 900 0 900 1 1
    BCL2 MAP1A 0 0 135 176 1 1
    BCL2 PPP2R5D 0 600 0 600 1 1
    BCL2 DDIT3 0 800 184 833 1 2
    BCL2 LPP 0 0 0 254 1 1
    BCL2 CUL2 0 0 73 150 1 1
    BCL2 RAF1 865 0 162 882 1 2
    BCL2 VAMP4 0 0 0 207 1 1
    BCL2 GIMAP8 0 0 0 179 1 1
    BCL2 CISD1 0 0 73 297 1 1
    BCL2 PTPRU 0 0 0 298 1 1
    BCL2 MTOR 0 0 343 354 1 2
    BCL2 NLRP1 486 800 70 896 1 1
    BCL2 SPNS1 270 0 0 270 1 2
    BCL2 NOTCH1 0 0 202 259 1 1
    BCL2 RRAS 270 0 0 270 1 1
    BCL2 PSEN2 270 0 0 382 1 1
    BCL2 CXCR4 0 0 114 210 1 2
    BCL2 TNFRSF1A 0 0 206 206 1 1
    BCL2 ENDOG 0 0 142 171 1 1
    BCL2 STAT1 0 0 126 174 1 1
    BCL2 BRD2 270 0 0 270 1 1
    BCL2 IL6 0 0 261 261 1 1
    BCL2 PIK3C3 0 0 282 333 1 2
    BCL2 SMN1 270 0 0 270 1 1
    BCL2 CTSL 0 600 0 603 1 1
    BCL2 PPP2R2D 0 600 0 625 1 1
    BCL2 WNT7A 0 0 0 420 1 1
    BCL2 CXCL8 0 0 166 165 1 1
    BCL2 PLD4 0 0 0 170 1 1
    BCL2 KIAA1429 270 0 0 270 1 1
    BCL2 NAPG 0 0 0 181 1 1
    BCL2 IL1B 0 0 172 178 1 1
    BCL2 SP1 0 0 171 183 1 1
    BCL2 HIF1A 486 0 324 674 1 2
    BCL2 PRRC2A 0 0 0 222 1 1
    BCL2 BAG3 462 0 122 526 1 2
    BCL2 WNT7B 0 0 0 248 1 1
    BCL2 DNM3 0 0 0 280 1 1
    BCL2 ELK1 0 0 113 208 1 1
    BCL2 PRKAR2B 0 900 0 903 1 1
    BCL2 PASK 0 0 143 284 1 1
    BCL2 WNT2B 0 0 63 386 1 1
    BCL2 MFN2 0 0 143 375 1 2
    BCL2 CDK2 270 0 246 484 1 1
    BCL2 GIMAP5 270 0 67 374 1 1
    BCL2 CTNNB1 0 0 254 258 1 1
    BCL2 HRAS 213 0 218 368 1 1
    BCL2 C7 0 720 0 724 1 1
    BCL2 PRRC2B 0 0 0 189 1 1
    BCL2 RELA 270 0 117 327 1 1
    BCL2 BCL2L1 870 900 625 987 1 2
    BCL2 HMGB2 0 0 60 158 1 1
    BCL2 TOMM7 0 0 42 210 1 1
    BCL2 NFKB1 0 0 181 283 1 1
    BCL2 STAT4 0 0 0 185 1 1
    BCL2 CASP6 0 0 155 329 1 1
    BCL2 ITPR2 0 0 90 174 1 1
    BCL2 WIF1 0 0 67 385 1 1
    BCL2 HIST1H2AC 0 900 0 900 1 1
    BCL2 NOS2 0 0 203 203 1 1
    BCL2 PPIE 0 0 61 173 1 1
    BCL2 MAP2K7 0 0 204 204 1 1
    BCL2 ABL1 0 0 146 162 1 1
    BCL2 AGPAT5 0 0 0 216 1 1
    BCL2 FKBP8 874 900 45 986 1 1
    BCL2 PPP2R3C 0 600 0 600 1 1
    BCL2 GAPDH 0 0 334 335 1 2
    BCL2 ATG14 0 0 167 219 1 2
    BCL2 BNIPL 270 0 0 270 1 1
    BCL2 SMAD2 0 0 136 157 1 1
    BCL2 PML 270 0 73 305 1 1
    BCL2 TLR4 0 0 125 159 1 1
    BCL2 CREB1 0 900 167 913 1 1
    BCL2 USP9X 0 0 125 197 1 1
    BCL2 SPSB2 0 0 0 248 1 1
    BCL2 DHX37 0 0 0 302 1 1
    BCL2 BIRC2 0 0 210 241 1 1
    BCL2 IFNG 0 0 82 167 1 2
    BCL2 CREBBP 0 900 74 903 1 1
    BCL2 PPID 270 800 102 859 1 1
    BCL2 PRKACA 213 0 0 219 1 1
    BCL2 RECK 0 0 139 171 1 1
    BCL2 NOTCH4 0 0 63 158 1 1
    BCL2 SYNGR1 0 0 0 181 1 1
    BCL2 ABAT 0 0 0 384 1 1
    BCL2 NCS1 0 0 54 353 1 1
    BCL2 PPP2R2A 0 600 0 625 1 1
    BCL2 HSPD1 0 0 0 161 1 1
    BCL2 HES1 0 0 134 152 1 1
    BCL2 TNFSF13 0 0 0 160 1 1
    BCL2 ANXA5 0 0 380 418 1 1
    BCL2 CCNB1 0 0 167 192 1 1
    BCL2 SOD2 0 0 134 167 1 1
    BCL2 FOXO1 0 0 181 194 1 2
    BCL2 KRAS 462 0 194 558 1 1
    BCL2 FTH1 0 0 72 171 1 1
    BCL2 DNM1 0 0 0 280 1 1
    BCL2 E2F1 0 0 172 202 1 1
    BCL2 HSPA5 0 0 193 193 1 2
    BCL2 CASP14 0 0 45 203 1 1
    BCL2 NRAS 213 0 113 302 1 1
    BCL2 CRKL 0 0 0 462 1 1
    BCL2 RAD1 0 0 66 162 1 1
    BCL2 PPAT 0 0 0 446 1 1
    BCL2 PPAPDC2 0 0 0 238 1 1
    BCL2 RXRA 0 900 0 901 1 1
    BCL2 LMO2 0 0 351 369 1 1
    BCL2 PRKAR1A 0 900 54 903 1 2
    BCL2 AIFM3 0 0 0 150 1 1
    BCL2 FASLG 0 0 219 219 1 1
    BCL2 FOS 0 0 195 201 1 1
    BCL2 RXRB 0 900 0 903 1 1
    BCL2 CDC25A 0 0 123 156 1 1
    BCL2 PDZD11 0 720 0 720 1 1
    BCL2 GFM2 0 0 0 359 1 1
    BCL2 CCSER2 0 0 0 177 1 1
    BCL2 LRRK2 270 0 0 328 1 2
    BCL2 TM9SF2 0 0 0 206 1 1
    BCL2 PMAIP1 799 800 406 976 1 1
    BCL2 PEA15 0 0 134 286 1 1
    BCL2 MAPK11 213 0 65 298 1 1
    BCL2 SPATA4 0 0 0 216 1 1
    BCL2 ABCC1 0 0 193 193 1 1
    BCL2 HIST1H2BB 0 900 0 900 1 1
    BCL2 SUFU 0 0 134 153 1 1
    BCL2 NAPA 0 0 0 181 1 1
    BCL2 BECN1 992 800 880 999 1 2
    BCL2 TMBIM1 0 0 57 174 1 1
    BCL2 OMA1 0 0 0 190 1 1
    BCL2 CD5 0 0 359 382 1 1
    BCL2 ATG12 270 0 180 513 1 2
    BCL2 TNFRSF10B 0 0 163 163 1 1
    BCL2 CTSS 0 600 0 603 1 1
    BCL2 PTGS2 0 0 171 193 1 1
    BCL2 CASP3 463 0 595 818 1 2
    BCL2 DAXX 0 0 147 165 1 1
    BCL2 PRELID1 0 0 0 178 1 1
    BCL2 CARD16 0 0 0 200 1 1
    BCL2 CTSZ 0 600 0 614 1 1
    BCL2 TFB2M 0 0 0 256 1 1
    BCL2 CRYAB 270 0 0 295 1 1
    BCL2 FGF11 0 0 0 177 1 1
    BCL2 WNT3 0 0 49 262 1 1
    BCL2 ARRDC3 0 0 117 189 1 1
    BCL2 ATG16L1 0 0 89 155 1 2
    BCL2 CHUK 270 0 134 340 1 1
    BCL2 CUL3 0 0 90 160 1 1
    BCL2 WNT2 0 0 57 377 1 1
    BCL2 GPX8 0 0 71 164 1 1
    BCL2 GSK3B 0 0 143 201 1 2
    BCL2 BLK 270 0 0 298 1 1
    BCL2 CDKN2A 0 0 228 240 1 2
    BCL2 CASP4 0 0 108 256 1 2
    BCL2 SAMD12 0 0 95 151 1 1
    BCL2 ATM 0 0 181 196 1 1
    BCL2 ITGA2B 0 900 0 900 1 1
    BCL2 CTSD 0 600 61 608 1 2
    BCL2 CCL3 0 0 270 312 1 1
    BCL2 MDM4 486 0 0 494 1 1
    BCL2 PLEKHA7 0 720 0 724 1 1
    BCL2 FAIM2 270 0 55 332 1 1
    BCL2 RXRG 0 900 0 901 1 1
    BCL2 RBBP8NL 0 0 0 303 1 1
    BCL2 ATG7 0 0 202 232 1 2
    BCL2 NAMPT 0 0 73 309 1 1
    BCL2 SNX17 0 0 0 153 1 1
    BCL2 CABLES2 0 0 0 228 1 1
    BCL2 EFNB2 0 0 0 302 1 1
    BCL2 MTDH 0 0 82 178 1 2
    BCL2 PPP3R1 270 0 70 365 1 1
    BCL2 PTEN 0 0 324 353 1 2
    BCL2 ACTR1A 0 0 0 181 1 1
    BCL2 IRF4 0 0 64 186 1 1
    BCL2 VEGFA 0 0 293 293 1 1
    BCL2 PRKAA2 0 0 434 434 1 2
    BCL2 PCDH9 0 0 90 247 1 1
    BCL2 ISOC1 0 0 122 162 1 1
    BCL2 CASP5 0 0 91 241 1 1
    BCL2 DNM1L 0 0 113 301 1 2
    BCL2 WIPI1 0 0 88 187 1 2
    BCL2 S1PR1 0 0 103 348 1 1
    BCL2 KIT 0 0 304 304 1 1
    BCL2 NFKBIA 0 0 145 186 1 1
    BCL2 H2BFS 0 900 0 900 1 1
    BCL2 AMBRA1 312 0 113 384 1 2
    BCL2 E2F3 0 0 160 221 1 1
    BCL2 BAG1 500 0 261 621 1 2
    BCL2 TP53BP2 680 0 167 726 1 1
    BCL2 CD79A 0 0 107 246 1 1
    BCL2 MAPK10 0 800 67 811 1 2
    BCL2 MAPK14 213 0 112 316 1 1
    BCL2 SIRT1 0 0 210 210 1 2
    BCL2 MCL1 492 900 561 958 1 2
    BCL2 CTSB 0 600 108 636 1 2
    BCL2 SULT1E1 0 0 0 264 1 1
    BCL2 CTSK 0 600 0 603 1 1
    BCL2 ESR1 0 900 244 924 1 1
    BCL2 TSPAN33 0 720 0 727 1 1
    BCL2 PPP1CA 275 0 0 303 1 1
    BCL2 HMGB1 0 0 96 236 1 2
    BCL2 BCL2L14 213 0 134 289 1 1
    BCL2 TRIP6 0 0 0 185 1 1
    BCL2 LRPPRC 270 0 141 346 1 1
    BCL2 ATG5 0 0 247 325 1 2
    BCL2 PPP2R2C 0 600 0 625 1 1
    BCL2 WNT3A 0 0 74 479 1 1
    BCL2 MYBL2 0 0 503 503 1 1
    BCL2 PRKAG2 0 0 0 190 1 1
    BCL2 CASP16 0 0 0 200 1 1
    BCL2 GLI1 0 0 143 156 1 1
    BCL2 EBP 0 0 66 277 1 1
    BCL2 SERPINB8 270 0 0 291 1 1
    BCL2 WDFY4 0 0 0 158 1 1
    BCL2 MAP1LC3B 0 0 234 262 1 2
    BCL2 SPHK2 270 0 0 270 1 1
    BCL2 ULK1 0 0 122 155 1 2
    BCL2 SKIL 0 0 0 207 1 1
    BCL2 PRKCA 213 0 97 258 1 1
    BCL2 AKT3 0 800 81 813 1 1
    BCL2 RAG2 0 0 96 191 1 1
    BCL2 IKBKG 270 0 74 295 1 1
    BCL2 RARA 0 0 277 309 1 1
    BCL2 TFAP2A 0 900 0 900 1 1
    BCL2 TFRC 0 0 123 159 1 1
    BCL2 METTL13 0 0 0 258 1 1
    BCL2 CCND2 0 0 359 359 1 1
    BCL2 PCDH10 0 0 0 252 1 1
    BCL2 C8G 0 540 0 540 1 1
    BCL2 DRAM1 0 0 139 165 1 2
    BCL2 BCAP31 297 0 95 336 1 1
    BCL2 BMF 486 600 369 879 1 1
    BCL2 BCL2A1 0 900 380 913 1 1
    BCL2 PPP2R5C 0 600 0 600 1 1
    BCL2 GPR115 0 0 108 245 1 1
    BCL2 UVRAG 0 0 207 261 1 2
    BCL2 PPP2R2B 0 600 0 647 1 1
    BCL2 ANAPC2 0 0 73 160 1 1
    BCL2 MAPK1 462 900 222 954 1 2
    BCL2 PPP2R1A 0 600 0 600 1 1
    BCL2 IGF1 0 0 205 413 1 1
    BCL2 BTK 0 0 134 185 1 1
    BCL2 HNRNPD 192 0 73 218 1 1
    BCL2 TNF 0 0 233 308 1 1
    BCL2 PRRC2C 0 0 0 222 1 1
    BCL2 C22orf29 270 0 339 496 1 1
    BCL2 BDNF 0 0 154 153 1 2
    BCL2 GFER 0 0 437 437 1 1
    BCL2 AEN 0 0 144 162 1 1
    BCL2 CASP2 209 0 236 474 1 1
    BCL2 C6 0 720 53 730 1 1
    BCL2 BAG4 213 0 76 328 1 1
    BCL2 FIS1 0 0 139 178 1 2
    BCL2 SYN2 0 0 52 209 1 1
    BCL2 DFFA 0 0 139 168 1 1
    BCL2 CARD18 0 0 0 200 1 1
    BCL2 PPP2R3A 0 600 0 618 1 1
    BCL2 ATP2A2 213 0 47 217 1 1
    BCL2 POLG2 0 0 0 190 1 1
    BCL2 HSD17B1 0 0 52 254 1 1
    BCL2 MDK 0 0 0 197 1 1
    BCL2 PPP2R5E 0 600 0 600 1 1
    BCL2 MAP2K2 0 0 0 303 1 1
    BCL2 CD38 0 0 81 176 1 1
    BCL2 BAK1 756 900 503 979 1 2
    BCL2 AVEN 270 0 96 316 1 1
    BCL2 CANX 0 0 45 167 1 2
    BCL2 HRK 867 0 322 905 1 1
    BCL2 CCNE1 0 0 120 175 1 1
    BCL2 RASA1 0 0 108 170 1 1
    BCL2 PTK2B 0 0 0 184 1 1
    BCL2 CAT 0 0 167 167 1 1
    BCL2 STEAP2 0 0 67 174 1 1
    BCL2 BARD1 273 0 0 296 1 1
    BCL2 REM1 0 0 0 214 1 1
    BCL2 BAD 882 900 505 995 1 1
    BCL2 RPS6KB1 0 0 150 198 1 2
    BCL2 PPP2CA 486 600 52 794 1 1
    BCL2 SERPINE1 0 0 102 198 1 1
    BCL2 HIST2H2BE 0 900 0 900 1 1
    BCL2 PGR 0 0 167 264 1 1
    BCL2 EIF4E 0 0 137 160 1 1
    BCL2 CDK1 675 0 113 715 1 1
    BCL2 DRD1 0 0 54 158 1 1
    BCL2 IRS1 270 0 113 324 1 1
    BCL2 HSPA9 282 0 141 356 1 1
    BCL2 C8A 0 720 0 732 1 1
    BCL2 FAU 0 0 0 163 1 1
    BCL2 GREB1 0 0 0 189 1 1
    BCL2 UBE2I 270 0 0 270 1 1
    BCL2 CD19 0 0 123 167 1 1
    BCL2 HSF2 0 0 127 153 1 1
    BCL2 CCND1 0 0 402 443 1 1
    BCL2 CPM 0 0 122 273 1 1
    BCL2 THOC1 0 0 0 236 1 1
    BCL2 VDAC3 0 540 182 637 1 1
    BCL2 FOXO3 0 0 211 253 1 2
    BCL2 GATA5 0 0 0 190 1 1
    BCL2 SPRED1 0 0 74 156 1 1
    BCL2 PKMYT1 213 0 0 219 1 1
    BCL2 DAP3 0 0 75 282 1 1
    BCL2 SRC 0 0 193 211 1 1
    BCL2 DOCK2 0 0 0 159 1 1
    BCL2 CDC42 0 0 101 400 1 1
    BCL2 BNIP1 270 0 71 292 1 2
    BCL2 EIF2AK3 0 0 205 222 1 2
    BCL2 TOMM40L 0 540 0 540 1 1
    BCL2 RTN3 270 0 0 300 1 1
    BCL2 HMOX1 0 0 194 194 1 2
    BCL2 PDE9A 0 0 95 581 1 1
    BCL2 ATG2B 0 0 155 154 1 2
    BCL2 TOMM20 270 0 49 291 1 1
    BCL2 MITF 0 900 306 927 1 1
    BCL2 JAK1 0 900 108 908 1 1
    BCL2 HIST1H2BJ 0 900 0 900 1 1
    BCL2 BNIP3L 486 0 217 594 1 2
    BCL2 IQSEC2 0 0 580 589 1 1
    BCL2 PPP2R3B 0 600 0 618 1 1
    BCL2 VDAC1 270 720 384 865 1 2
    BCL2 TGFB1 0 0 106 161 1 1
    BCL2 RB1 0 0 187 254 1 2
    BCL2 HSD17B2 0 0 49 212 1 1
    BCL2 CDKN1B 0 0 218 243 1 2
    BCL2 PPARG 0 0 141 175 1 1
    BCL2 AKT1 0 900 455 944 1 2
    BCL2 CPT1A 213 0 44 304 1 1
    BCL2 MKI67 0 0 93 233 1 1
    BCL2 SUMO1 0 0 404 404 1 1
    BCL2 FAS 0 0 263 263 1 2
    BCL2 CARD8 0 0 0 200 1 1
    BCL2 HIST1H2BA 0 900 0 900 1 1
    BCL2 CA9 0 0 108 163 1 1
    BCL2 ATP2A3 270 0 62 306 1 1
    BCL2 CD4 0 0 150 195 1 1
    BCL2 IKBKB 270 0 134 340 1 1
    BCL2 DROSHA 0 0 124 178 1 1
    BCL2 ANKS6 0 0 0 157 1 1
    BCL2 XIAP 270 0 310 540 1 1
    BCL2 SF1 213 0 0 219 1 1
    BCL2 PPP3CA 678 0 0 698 1 1
    BCL2 CLGN 0 0 0 163 1 1
    BCL2 BIRC5 0 0 218 408 1 2
    BCL2 PINK1 0 0 108 242 1 2
    BCL2 BCL6 0 0 356 366 1 1
    BCL2 RTN4 486 0 0 494 1 1
    BCL2 BIRC8 0 0 0 161 1 1
    BCL2 AIFM1 0 900 107 921 1 1
    BCL2 NMT2 270 0 0 275 1 1
    BCL2 ITM2B 270 0 81 309 1 1
    BCL2 CCNE2 0 0 90 190 1 1
    BCL2 CREM 0 800 43 822 1 1
    BCL2 HIST1H2BN 0 900 0 900 1 1
    BCL2 CTSO 0 600 0 615 1 1
    BCL2 CD34 0 720 123 743 1 1
    BCL2 ERBB2 0 0 248 248 1 2
    BCL2 HMGA2 0 0 70 168 1 1
    BCL2 BBC3 873 900 342 990 1 1
    BCL2 FBXO25 0 0 118 254 1 1
    BCL2 CTSC 0 600 0 603 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0051434 Molecular Function BH3 domain binding enables IPI
    GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
    GO:0015267 Molecular Function channel activity enables IBA
    GO:0015267 Molecular Function channel activity enables IDA
    GO:0016248 Molecular Function channel inhibitor activity enables IDA
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0060090 Molecular Function molecular adaptor activity enables EXP
    GO:0002020 Molecular Function protease binding enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0046982 Molecular Function protein heterodimerization activity enables IPI
    GO:0051721 Molecular Function protein phosphatase 2A binding enables IEA
    GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
    GO:0031625 Molecular Function ubiquitin protein ligase binding enables IPI
    GO:0001783 Biological Process B cell apoptotic process involved_in IEA
    GO:0001782 Biological Process B cell homeostasis involved_in IEA
    GO:0002326 Biological Process B cell lineage commitment involved_in IEA
    GO:0042100 Biological Process B cell proliferation acts_upstream_of_or_within IDA
    GO:0050853 Biological Process B cell receptor signaling pathway involved_in IMP
    GO:0043375 Biological Process CD8-positive, alpha-beta T cell lineage commitment involved_in IEA
    GO:0006974 Biological Process DNA damage response involved_in IMP
    GO:0000082 Biological Process G1/S transition of mitotic cell cycle involved_in IEA
    GO:0070231 Biological Process T cell apoptotic process involved_in IEA
    GO:0033077 Biological Process T cell differentiation in thymus involved_in IEA
    GO:0043029 Biological Process T cell homeostasis involved_in IEA
    GO:0007015 Biological Process actin filament organization involved_in IEA
    GO:0006915 Biological Process apoptotic process acts_upstream_of_or_within IDA
    GO:0006914 Biological Process autophagy involved_in IEA
    GO:0031103 Biological Process axon regeneration involved_in IEA
    GO:0007409 Biological Process axonogenesis involved_in IEA
    GO:0001662 Biological Process behavioral fear response involved_in IEA
    GO:0001658 Biological Process branching involved in ureteric bud morphogenesis involved_in IEA
    GO:0060402 Biological Process calcium ion transport into cytosol involved_in IEA
    GO:0098609 Biological Process cell-cell adhesion involved_in IEA
    GO:0042149 Biological Process cellular response to glucose starvation involved_in IEA
    GO:0071456 Biological Process cellular response to hypoxia involved_in IEA
    GO:0021747 Biological Process cochlear nucleus development involved_in IEA
    GO:0051607 Biological Process defense response to virus involved_in IDA
    GO:0097048 Biological Process dendritic cell apoptotic process involved_in IEA
    GO:0048546 Biological Process digestive tract morphogenesis involved_in IEA
    GO:0043583 Biological Process ear development involved_in IEA
    GO:0032469 Biological Process endoplasmic reticulum calcium ion homeostasis involved_in TAS
    GO:1904019 Biological Process epithelial cell apoptotic process involved_in IEA
    GO:0051649 Biological Process establishment of localization in cell involved_in IEA
    GO:0097192 Biological Process extrinsic apoptotic signaling pathway in absence of ligand involved_in IBA
    GO:0008625 Biological Process extrinsic apoptotic signaling pathway via death domain receptors acts_upstream_of_or_within IDA
    GO:0007565 Biological Process female pregnancy involved_in NAS
    GO:0048041 Biological Process focal adhesion assembly involved_in IEA
    GO:0022612 Biological Process gland morphogenesis involved_in IEA
    GO:0032835 Biological Process glomerulus development involved_in IEA
    GO:0031069 Biological Process hair follicle morphogenesis involved_in IEA
    GO:0060218 Biological Process hematopoietic stem cell differentiation involved_in IEA
    GO:0048873 Biological Process homeostasis of number of cells within a tissue involved_in IEA
    GO:0006959 Biological Process humoral immune response involved_in TAS
    GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IBA
    GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress acts_upstream_of_or_within IDA
    GO:0008631 Biological Process intrinsic apoptotic signaling pathway in response to oxidative stress involved_in IEA
    GO:0002320 Biological Process lymphoid progenitor cell differentiation involved_in IEA
    GO:0008584 Biological Process male gonad development involved_in IEA
    GO:0006582 Biological Process melanin metabolic process involved_in IEA
    GO:0030318 Biological Process melanocyte differentiation involved_in IEA
    GO:0014031 Biological Process mesenchymal cell development involved_in IEA
    GO:0001656 Biological Process metanephros development involved_in IEA
    GO:0097049 Biological Process motor neuron apoptotic process involved_in IEA
    GO:0033028 Biological Process myeloid cell apoptotic process involved_in IEA
    GO:0002903 Biological Process negative regulation of B cell apoptotic process involved_in IEA
    GO:2000134 Biological Process negative regulation of G1/S transition of mitotic cell cycle involved_in IEA
    GO:0070233 Biological Process negative regulation of T cell apoptotic process involved_in IEA
    GO:2000811 Biological Process negative regulation of anoikis involved_in IMP
    GO:0043066 Biological Process negative regulation of apoptotic process acts_upstream_of_or_within IDA
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in IDA
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in IGI
    GO:0043066 Biological Process negative regulation of apoptotic process acts_upstream_of_or_within IMP
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in IMP
    GO:2001234 Biological Process negative regulation of apoptotic signaling pathway involved_in IMP
    GO:0010507 Biological Process negative regulation of autophagy involved_in IDA
    GO:0010507 Biological Process negative regulation of autophagy involved_in TAS
    GO:0010523 Biological Process negative regulation of calcium ion transport into cytosol involved_in IEA
    GO:0030308 Biological Process negative regulation of cell growth involved_in IEA
    GO:0030336 Biological Process negative regulation of cell migration involved_in IEA
    GO:0032848 Biological Process negative regulation of cellular pH reduction involved_in IDA
    GO:2000669 Biological Process negative regulation of dendritic cell apoptotic process involved_in IEA
    GO:1904036 Biological Process negative regulation of epithelial cell apoptotic process involved_in IEA
    GO:2001240 Biological Process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand acts_upstream_of_or_within IGI
    GO:2001243 Biological Process negative regulation of intrinsic apoptotic signaling pathway involved_in IDA
    GO:1902166 Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator involved_in TAS
    GO:0051902 Biological Process negative regulation of mitochondrial depolarization involved_in TAS
    GO:2000672 Biological Process negative regulation of motor neuron apoptotic process involved_in IEA
    GO:0033033 Biological Process negative regulation of myeloid cell apoptotic process involved_in IEA
    GO:0043524 Biological Process negative regulation of neuron apoptotic process acts_upstream_of_or_within IDA
    GO:0030279 Biological Process negative regulation of ossification involved_in IEA
    GO:0033689 Biological Process negative regulation of osteoblast proliferation involved_in IEA
    GO:0046671 Biological Process negative regulation of retinal cell programmed cell death involved_in IEA
    GO:0051402 Biological Process neuron apoptotic process involved_in TAS
    GO:0042551 Biological Process neuron maturation involved_in IEA
    GO:0048599 Biological Process oocyte development involved_in IEA
    GO:0035265 Biological Process organ growth involved_in IEA
    GO:0001503 Biological Process ossification involved_in IEA
    GO:0033687 Biological Process osteoblast proliferation involved_in IEA
    GO:0001541 Biological Process ovarian follicle development involved_in IEA
    GO:0048753 Biological Process pigment granule organization involved_in IEA
    GO:0030890 Biological Process positive regulation of B cell proliferation involved_in IMP
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IBA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in NAS
    GO:0030307 Biological Process positive regulation of cell growth acts_upstream_of_or_within IDA
    GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IGI
    GO:0045636 Biological Process positive regulation of melanocyte differentiation involved_in IEA
    GO:0040018 Biological Process positive regulation of multicellular organism growth involved_in IEA
    GO:0014042 Biological Process positive regulation of neuron maturation involved_in IEA
    GO:0048743 Biological Process positive regulation of skeletal muscle fiber development involved_in IEA
    GO:0014911 Biological Process positive regulation of smooth muscle cell migration involved_in IEA
    GO:0009791 Biological Process post-embryonic development involved_in IEA
    GO:0000209 Biological Process protein polyubiquitination acts_upstream_of_or_within IDA
    GO:0072593 Biological Process reactive oxygen species metabolic process involved_in IEA
    GO:0051924 Biological Process regulation of calcium ion transport acts_upstream_of_or_within IDA
    GO:0001952 Biological Process regulation of cell-matrix adhesion involved_in IEA
    GO:0010468 Biological Process regulation of gene expression involved_in IEA
    GO:0010559 Biological Process regulation of glycoprotein biosynthetic process involved_in IEA
    GO:0046902 Biological Process regulation of mitochondrial membrane permeability involved_in ISS
    GO:0051881 Biological Process regulation of mitochondrial membrane potential involved_in ISS
    GO:0006808 Biological Process regulation of nitrogen utilization involved_in IEA
    GO:0032880 Biological Process regulation of protein localization involved_in IEA
    GO:0031647 Biological Process regulation of protein stability involved_in IEA
    GO:0022898 Biological Process regulation of transmembrane transporter activity involved_in IDA
    GO:0045069 Biological Process regulation of viral genome replication involved_in IEA
    GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IBA
    GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in ISS
    GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in NAS
    GO:0003014 Biological Process renal system process involved_in IEA
    GO:0010224 Biological Process response to UV-B involved_in IEA
    GO:0034097 Biological Process response to cytokine acts_upstream_of_or_within IDA
    GO:0010332 Biological Process response to gamma radiation involved_in IEA
    GO:0051384 Biological Process response to glucocorticoid involved_in IEA
    GO:0042542 Biological Process response to hydrogen peroxide involved_in IEA
    GO:0010039 Biological Process response to iron ion involved_in IDA
    GO:0002931 Biological Process response to ischemia involved_in IEA
    GO:0035094 Biological Process response to nicotine involved_in IDA
    GO:0009314 Biological Process response to radiation involved_in NAS
    GO:0009636 Biological Process response to toxic substance acts_upstream_of_or_within IDA
    GO:0009636 Biological Process response to toxic substance involved_in IDA
    GO:0009410 Biological Process response to xenobiotic stimulus acts_upstream_of_or_within IDA
    GO:0009410 Biological Process response to xenobiotic stimulus involved_in IMP
    GO:0046666 Biological Process retinal cell programmed cell death involved_in IEA
    GO:0048741 Biological Process skeletal muscle fiber development involved_in IEA
    GO:0014909 Biological Process smooth muscle cell migration involved_in IEA
    GO:0048536 Biological Process spleen development involved_in IEA
    GO:0048864 Biological Process stem cell development involved_in IEA
    GO:0048538 Biological Process thymus development involved_in IEA
    GO:0097138 Cellular Component BAD-BCL-2 complex part_of IPI
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in IEA
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane is_active_in IDA
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IBA
    GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IDA
    GO:0005741 Cellular Component mitochondrial outer membrane located_in IDA
    GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
    GO:0005739 Cellular Component mitochondrion located_in HTP
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0043209 Cellular Component myelin sheath located_in IEA
    GO:0031965 Cellular Component nuclear membrane located_in IDA
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0046930 Cellular Component pore complex part_of IDA
    GO:0032991 Cellular Component protein-containing complex part_of IMP
    Pathways
    Name DB ID
    Apoptosis Reactome R-HSA-109581
    Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
    Activation of BAD and translocation to mitochondria Reactome R-HSA-111447
    BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Reactome R-HSA-111453
    Activation of BH3-only proteins Reactome R-HSA-114452
    Cytokine Signaling in Immune system Reactome R-HSA-1280215
    Signal Transduction Reactome R-HSA-162582
    Innate Immune System Reactome R-HSA-168249
    Immune System Reactome R-HSA-168256
    Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Reactome R-HSA-168643
    Signaling by Interleukins Reactome R-HSA-449147
    Programmed Cell Death Reactome R-HSA-5357801
    Inflammasomes Reactome R-HSA-622312
    Interleukin-4 and Interleukin-13 signaling Reactome R-HSA-6785807
    The NLRP1 inflammasome Reactome R-HSA-844455
    ESR-mediated signaling Reactome R-HSA-8939211
    Signaling by Nuclear Receptors Reactome R-HSA-9006931
    Extra-nuclear estrogen signaling Reactome R-HSA-9009391
    Estrogen-dependent gene expression Reactome R-HSA-9018519
    Estrogen-dependent nuclear events downstream of ESR-membrane signaling Reactome R-HSA-9634638
    Focal adhesion (WP306) WikiPathways WP306_r116784
    Neuroinflammation and glutamatergic signaling (WP5083) WikiPathways WP5083_r120385
    Interleukin-11 signaling pathway (WP2332) WikiPathways WP2332_r120725
    Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
    Vitamin D-sensitive calcium signaling in depression (WP4698) WikiPathways WP4698_r123493
    Chromosomal and microsatellite instability in colorectal cancer (WP4216) WikiPathways WP4216_r123363
    Measles virus infection (WP4630) WikiPathways WP4630_r123414
    Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
    Nanomaterial induced apoptosis (WP2507) WikiPathways WP2507_r123897
    EGFR tyrosine kinase inhibitor resistance (WP4806) WikiPathways WP4806_r123492
    MicroRNA network associated with chronic lymphocytic leukemia (WP4399) WikiPathways WP4399_r102102
    Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
    IL-3 signaling pathway (WP286) WikiPathways WP286_r120663
    Amyotrophic lateral sclerosis (ALS) (WP2447) WikiPathways WP2447_r113794
    miRNA regulation of prostate cancer signaling pathways (WP3981) WikiPathways WP3981_r108114
    Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
    Estrogen signaling pathway (WP712) WikiPathways WP712_r109450
    Prion disease pathway (WP3995) WikiPathways WP3995_r119304
    Corticotropin-releasing hormone signaling pathway (WP2355) WikiPathways WP2355_r120664
    NO/cGMP/PKG mediated neuroprotection (WP4008) WikiPathways WP4008_r123318
    Burn wound healing (WP5055) WikiPathways WP5055_r122621
    IL-5 signaling pathway (WP127) WikiPathways WP127_r120669
    Overview of nanoparticle effects (WP3287) WikiPathways WP3287_r121705
    IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
    Acute viral myocarditis (WP4298) WikiPathways WP4298_r123508
    22q11.2 copy number variation syndrome (WP4657) WikiPathways WP4657_r120007
    Oxidative damage response (WP3941) WikiPathways WP3941_r123242
    DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
    Fas ligand pathway and stress induction of heat shock proteins (WP314) WikiPathways WP314_r121827
    Unfolded protein response (WP4925) WikiPathways WP4925_r123438
    IL-2 signaling pathway (WP49) WikiPathways WP49_r120703
    Regulation of apoptosis by parathyroid hormone-related protein (WP3872) WikiPathways WP3872_r123397
    Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
    Host-pathogen interaction of human coronaviruses - apoptosis (WP4864) WikiPathways WP4864_r124634
    Hematopoietic stem cell gene regulation by GABP alpha/beta complex (WP3657) WikiPathways WP3657_r123358
    TP53 network (WP1742) WikiPathways WP1742_r116592
    Apoptosis (WP254) WikiPathways WP254_r118382
    Hippocampal synaptogenesis and neurogenesis (WP5231) WikiPathways WP5231_r123335
    Host-pathogen interaction of human coronaviruses - MAPK signaling (WP4877) WikiPathways WP4877_r124642
    Influenza A virus infection (WP1438) WikiPathways WP1438_r108357
    Photodynamic therapy-induced AP-1 survival signaling (WP3611) WikiPathways WP3611_r120501
    Male infertility (WP4673) WikiPathways WP4673_r119920
    Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
    Nanoparticle triggered autophagic cell death (WP2509) WikiPathways WP2509_r101755
    Kit receptor signaling pathway (WP304) WikiPathways WP304_r120696
    Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
    PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    Hedgehog signaling pathway (WP4249) WikiPathways WP4249_r117749
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_047437733 1 mRNA transcript variant X1 NC_000018 Reference
    NM_000633 3 mRNA transcript variant alpha NC_000018 Reference
    XM_047437734 1 mRNA transcript variant X4 NC_000018 Reference
    XM_017025917 3 mRNA transcript variant X3 NC_000018 Reference
    XM_011526135 4 mRNA transcript variant X2 NC_000018 Reference
    NM_000657 3 mRNA transcript variant beta NC_000018 Reference