RB1

RB transcriptional corepressor 1
General Information
Name RB transcriptional corepressor 1
Alias
  • retinoblastoma-associated protein
  • prepro-retinoblastoma-associated protein
  • protein phosphatase 1, regulatory subunit 130
  • retinoblastoma 1
  • retinoblastoma suspectibility protein
Synonyms RB PPP1R130 OSRC p105-Rb p110-RB1 pRb pp110
Gene_family Receptor ligands
organism Homo sapiens
entrez_id 5925
location 13q14.2
transcript_count 5
exon_count 29
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
      Stringdb Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...]
      nextProt (Microbial infection) In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    RB1 BioGRID CUL2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID HDAC2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CDK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID E2F1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-localization; Proximity Label-MS; Reconstituted Complex; Two-hybrid
    RB1 BioGRID E7 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-purification; PCA; Reconstituted Complex; Two-hybrid
    RB1 BioGRID E7 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID UBE3A GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
    RB1 BioGRID CTBP1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID DCAF7 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID DZIP3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RPA2 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
    RB1 BioGRID RPA1 GeneID BioGRID Proximity Label-MS
    RB1 BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID SETDB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CFH GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID KEAP1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID NCF1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID HAPSTR1 GeneID BioGRID Positive Genetic
    RB1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID CBX1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
    RB1 BioGRID H3C3 GeneID BioGRID Proximity Label-MS
    RB1 BioGRID TIPARP GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID H3-3A GeneID BioGRID Proximity Label-MS
    RB1 BioGRID MTA3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID E2F4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
    RB1 BioGRID E2F3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RB1 BioGRID TFDP2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RB1 BioGRID TFDP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RB1 BioGRID FSCN1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID KPNA4 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID KPNA3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID DYRK1B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; FRET
    RB1 BioGRID DYRK1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; FRET
    RB1 BioGRID ORF1ab GeneID BioGRID Reconstituted Complex
    RB1 BioGRID VGLL3 GeneID BioGRID Negative Genetic
    RB1 BioGRID NHLRC2 GeneID BioGRID Co-fractionation
    RB1 BioGRID STAC2 GeneID BioGRID Negative Genetic
    RB1 BioGRID ANKRD52 GeneID BioGRID Negative Genetic
    RB1 BioGRID UNC13D GeneID BioGRID Negative Genetic
    RB1 BioGRID TADA1 GeneID BioGRID Negative Genetic
    RB1 BioGRID NPEPL1 GeneID BioGRID Co-fractionation
    RB1 BioGRID SAP130 GeneID BioGRID Negative Genetic
    RB1 BioGRID ACD GeneID BioGRID Negative Genetic
    RB1 BioGRID GOLPH3 GeneID BioGRID Co-fractionation
    RB1 BioGRID ELMO2 GeneID BioGRID Negative Genetic
    RB1 BioGRID SEPTIN11 GeneID BioGRID Co-fractionation
    RB1 BioGRID CCAR1 GeneID BioGRID Negative Genetic
    RB1 BioGRID DDX19A GeneID BioGRID Negative Genetic
    RB1 BioGRID PPP2R3C GeneID BioGRID Negative Genetic
    RB1 BioGRID SIRT7 GeneID BioGRID Negative Genetic
    RB1 BioGRID MSH2 GeneID BioGRID Co-fractionation
    RB1 BioGRID MCM6 GeneID BioGRID Co-fractionation
    RB1 BioGRID MCM4 GeneID BioGRID Co-fractionation
    RB1 BioGRID MAPT GeneID BioGRID Co-fractionation
    RB1 BioGRID LMNB1 GeneID BioGRID Co-fractionation
    RB1 BioGRID LMNA GeneID BioGRID Affinity Capture-Luminescence; Co-fractionation; Co-localization; Reconstituted Complex
    RB1 BioGRID HNRNPU GeneID BioGRID Co-fractionation
    RB1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; FRET; Reconstituted Complex
    RB1 BioGRID GBE1 GeneID BioGRID Co-fractionation
    RB1 BioGRID GART GeneID BioGRID Negative Genetic
    RB1 BioGRID GAK GeneID BioGRID Negative Genetic
    RB1 BioGRID FLT3LG GeneID BioGRID Negative Genetic
    RB1 BioGRID FKBP4 GeneID BioGRID Co-fractionation
    RB1 BioGRID ENO3 GeneID BioGRID Negative Genetic
    RB1 BioGRID DNMT1 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex
    RB1 BioGRID DLD GeneID BioGRID Co-fractionation
    RB1 BioGRID CTBP2 GeneID BioGRID Negative Genetic
    RB1 BioGRID CDK9 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-fractionation; Reconstituted Complex
    RB1 BioGRID RIN1 GeneID BioGRID Negative Genetic
    RB1 BioGRID NMI GeneID BioGRID Co-fractionation
    RB1 BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID UMPS GeneID BioGRID Negative Genetic
    RB1 BioGRID STAT6 GeneID BioGRID Negative Genetic
    RB1 BioGRID COMMD5 GeneID BioGRID Negative Genetic
    RB1 BioGRID COQ2 GeneID BioGRID Negative Genetic
    RB1 BioGRID TAF5L GeneID BioGRID Negative Genetic
    RB1 BioGRID TARDBP GeneID BioGRID Co-fractionation
    RB1 BioGRID SNW1 GeneID BioGRID Co-fractionation; Reconstituted Complex
    RB1 BioGRID EBNA1BP2 GeneID BioGRID Negative Genetic
    RB1 BioGRID FRS2 GeneID BioGRID Negative Genetic
    RB1 BioGRID HNRNPDL GeneID BioGRID Negative Genetic
    RB1 BioGRID MED13 GeneID BioGRID Negative Genetic
    RB1 BioGRID STAT1 GeneID BioGRID Co-fractionation
    RB1 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western; Negative Genetic
    RB1 BioGRID RPS6KB1 GeneID BioGRID Negative Genetic
    RB1 BioGRID RBBP7 GeneID BioGRID Affinity Capture-Western; Negative Genetic; Reconstituted Complex
    RB1 BioGRID PIN1 GeneID BioGRID Negative Genetic
    RB1 BioGRID P4HA1 GeneID BioGRID Negative Genetic
    RB1 BioGRID CCNT1 GeneID BioGRID Co-fractionation
    RB1 BioGRID ATP5PF GeneID BioGRID Negative Genetic
    RB1 BioGRID PARP1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    RB1 BioGRID HES1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RUNX2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CSNK2A2 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID CSNK2A1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOXM1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID PML GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID KLF15 GeneID BioGRID Proximity Label-MS
    RB1 BioGRID FZR1 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex
    RB1 BioGRID ANAPC2 GeneID BioGRID Affinity Capture-Western; Co-fractionation
    RB1 BioGRID CCL19 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RFC5 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID C2CD4B GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID PPP1R9B GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID CDK13 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FAS GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID PPAN GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID TFDP3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID B3GAT1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID KLK11 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RFPL2 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID CITED1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID GYPA GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID MDM2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID H2BC8 GeneID BioGRID Proximity Label-MS
    RB1 BioGRID TERF2IP GeneID BioGRID Proximity Label-MS
    RB1 BioGRID PCGF6 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID E2F6 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID E2F5 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID E2F2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
    RB1 BioGRID MKRN2 GeneID BioGRID Affinity Capture-RNA
    RB1 BioGRID ZBTB7A GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CDK4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID BRD4 GeneID BioGRID Affinity Capture-MS; Negative Genetic
    RB1 BioGRID CIC GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID UCHL1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID E7 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID SHC1 GeneID BioGRID Two-hybrid
    RB1 BioGRID GALNT12 GeneID BioGRID Two-hybrid
    RB1 BioGRID RASA1 GeneID BioGRID Two-hybrid
    RB1 BioGRID MAPK3 GeneID BioGRID Two-hybrid
    RB1 BioGRID FBP1 GeneID BioGRID Two-hybrid
    RB1 BioGRID FANCC GeneID BioGRID Two-hybrid
    RB1 BioGRID EP300 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID DVL1 GeneID BioGRID Two-hybrid
    RB1 BioGRID CTSV GeneID BioGRID Two-hybrid
    RB1 BioGRID MAPK14 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID CCDC180 GeneID BioGRID Two-hybrid
    RB1 BioGRID STX17 GeneID BioGRID Two-hybrid
    RB1 BioGRID TRMO GeneID BioGRID Two-hybrid
    RB1 BioGRID LEF1 GeneID BioGRID Two-hybrid
    RB1 BioGRID BAAT GeneID BioGRID Two-hybrid
    RB1 BioGRID FBP2 GeneID BioGRID Two-hybrid
    RB1 BioGRID XPA GeneID BioGRID Two-hybrid
    RB1 BioGRID CORO2A GeneID BioGRID Two-hybrid
    RB1 BioGRID E7 GeneID BioGRID PCA
    RB1 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID MYC GeneID BioGRID Affinity Capture-MS; FRET; Proximity Label-MS; Two-hybrid
    RB1 BioGRID CDK6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID EZH2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CBX4 GeneID BioGRID Affinity Capture-Western; Phenotypic Enhancement
    RB1 BioGRID CCND1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Phenotypic Suppression; Reconstituted Complex
    RB1 BioGRID RB1 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
    RB1 BioGRID CCNA2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID AHR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID SMARCA2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PSMD10 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
    RB1 BioGRID HSPA8 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID PPP1CA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID UL122 GeneID BioGRID Reconstituted Complex; Two-hybrid
    RB1 BioGRID ORC1 GeneID BioGRID Affinity Capture-Western; FRET; Reconstituted Complex
    RB1 BioGRID NPM1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID MRPS18B GeneID BioGRID Reconstituted Complex
    RB1 BioGRID ID2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID EID1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID ZBTB16 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RBBP8 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID Ifi211 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID POLD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID MYCN GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID DNMT3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RNF123 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID CBX3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID CCND2 GeneID BioGRID Biochemical Activity
    RB1 BioGRID SV40gp6 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CCND3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID CEBPA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RB1 BioGRID CDK1 GeneID BioGRID Biochemical Activity
    RB1 BioGRID vIRF-1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID UHRF2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Far Western; Reconstituted Complex
    RB1 BioGRID WEE1 GeneID BioGRID Synthetic Lethality
    RB1 BioGRID HSP90AA1 GeneID BioGRID Synthetic Lethality
    RB1 BioGRID TUBA1A GeneID BioGRID Synthetic Lethality
    RB1 BioGRID PCGF3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID HELZ GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID MARF1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID C3orf62 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID TASOR GeneID BioGRID Two-hybrid
    RB1 BioGRID BRCA1 GeneID BioGRID Affinity Capture-Western; Co-localization; Negative Genetic; Reconstituted Complex
    RB1 BioGRID NFATC2 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID PPP1R26 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID MDM4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID FOXK1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOXK2 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOXO3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOXO1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOXA3 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID MED23 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    RB1 BioGRID UBL4A GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID BAG6 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RBM26 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID RPRD1B GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID HERC4 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID ANKS1A GeneID BioGRID Two-hybrid
    RB1 BioGRID KDM5B GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID RABGAP1L GeneID BioGRID Two-hybrid
    RB1 BioGRID GRB2 GeneID BioGRID Affinity Capture-Luminescence; Two-hybrid
    RB1 BioGRID CHN2 GeneID BioGRID Two-hybrid
    RB1 BioGRID CLNK GeneID BioGRID Two-hybrid
    RB1 BioGRID GTF3C2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RBBP6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID NTRK1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID PAX8 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PA2G4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RAF1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
    RB1 BioGRID ABL1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID KDM2A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID SMARCA4 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Two-hybrid
    RB1 BioGRID USP7 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID NEFM GeneID BioGRID Reconstituted Complex
    RB1 BioGRID MAGEA11 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID ENC1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CDKN1C GeneID BioGRID Reconstituted Complex
    RB1 BioGRID CDKN1A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CCNE1 GeneID BioGRID Biochemical Activity
    RB1 BioGRID HDAC11 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID PAX5 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID HIF1A GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
    RB1 BioGRID CEBPE GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CCNA1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID UBE2I GeneID BioGRID Biochemical Activity; Reconstituted Complex
    RB1 BioGRID TFAP2A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CDK3 GeneID BioGRID Biochemical Activity
    RB1 BioGRID CCNC GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    RB1 BioGRID CCNB1 GeneID BioGRID Biochemical Activity
    RB1 BioGRID Cdk2 GeneID BioGRID Biochemical Activity
    RB1 BioGRID PRKCB GeneID BioGRID Biochemical Activity
    RB1 BioGRID CASP8 GeneID BioGRID Biochemical Activity
    RB1 BioGRID PRMT2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CASP7 GeneID BioGRID Biochemical Activity
    RB1 BioGRID CASP6 GeneID BioGRID Biochemical Activity
    RB1 BioGRID CASP3 GeneID BioGRID Biochemical Activity
    RB1 BioGRID MAPK8 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID ATF2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CASP10 GeneID BioGRID Biochemical Activity
    RB1 BioGRID CASP9 GeneID BioGRID Biochemical Activity
    RB1 BioGRID KAT2B GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID H4C16 GeneID BioGRID Co-localization
    RB1 BioGRID PLA2G12A GeneID BioGRID Two-hybrid
    RB1 BioGRID CEBPB GeneID BioGRID Affinity Capture-Western; Far Western; Reconstituted Complex
    RB1 BioGRID INS GeneID BioGRID Co-purification
    RB1 BioGRID DGKZ GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID TOP2A GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PPIA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CDK14 GeneID BioGRID Biochemical Activity
    RB1 BioGRID NOTCH1 GeneID BioGRID Affinity Capture-MS
    RB1 BioGRID FOS GeneID BioGRID Reconstituted Complex
    RB1 BioGRID JUN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID RINT1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID GTF2H1 GeneID BioGRID Co-fractionation
    RB1 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PURA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID PAX2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PNO1 GeneID BioGRID Co-fractionation
    RB1 BioGRID UBTF GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CHEK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID CHEK1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
    RB1 BioGRID SPI1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID RBBP4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID PPP1CA GeneID BioGRID Two-hybrid
    RB1 BioGRID RBAK GeneID BioGRID Reconstituted Complex
    RB1 BioGRID KDM5A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID UHRF1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID UBR4 GeneID BioGRID Affinity Capture-MS; Co-localization
    RB1 BioGRID RBBP9 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    RB1 BioGRID BRF1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID CDC27 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
    RB1 BioGRID EBNA-3B/EBNA-3C GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID RNF40 GeneID BioGRID Reconstituted Complex; Two-hybrid
    RB1 BioGRID CDC16 GeneID BioGRID Affinity Capture-Western; Co-fractionation
    RB1 BioGRID PSMA7 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CDK5 GeneID BioGRID Biochemical Activity
    RB1 BioGRID MCM7 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID TRIM27 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-Western; Two-hybrid
    RB1 BioGRID LMO2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID IRF3 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
    RB1 BioGRID TCF3 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID TAL1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    RB1 BioGRID SP1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID LDB1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID ARID4A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID SMYD2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 BioGRID PRDM2 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
    RB1 BioGRID DNAJA2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID YY1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID USP4 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex
    RB1 BioGRID SKIL GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID SKI GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID HDAC3 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID Sin3a GeneID BioGRID Reconstituted Complex
    RB1 BioGRID STAT3 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
    RB1 BioGRID LIN9 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID LIN54 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID CBX5 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID KDM1A GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID KDM4A GeneID BioGRID Affinity Capture-Western; Two-hybrid
    RB1 BioGRID HMGA2 GeneID BioGRID Affinity Capture-Western; Far Western; Reconstituted Complex
    RB1 BioGRID SERPINB2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID AR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID PHB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID AURKB GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    RB1 Protein L3MBTL1 GeneID HPRD None
    RB1 Protein RBAK GeneID HPRD None
    RB1 Protein CDK9 GeneID HPRD None
    RB1 Protein TRIM27 GeneID HPRD None
    RB1 Protein PPP1CA GeneID HPRD None
    RB1 Protein MNDA GeneID HPRD None
    RB1 Protein KMT5C GeneID HPRD None
    RB1 Protein CDK14 GeneID HPRD None
    RB1 Protein LIN9 GeneID HPRD None
    RB1 Protein HBP1 GeneID HPRD None
    RB1 Protein BNC2 GeneID HPRD None
    RB1 Protein AATF GeneID HPRD None
    RB1 Protein PPP1CB GeneID HPRD None
    RB1 Protein ZBTB16 GeneID HPRD None
    RB1 Protein PELP1 GeneID HPRD None
    RB1 Protein CREG1 GeneID HPRD None
    RB1 Protein ARID3B GeneID HPRD None
    RB1 Protein MORF4L1 GeneID HPRD None
    RB1 Protein THOC1 GeneID HPRD None
    RB1 Protein KDM5B GeneID HPRD None
    RB1 Protein PRMT2 GeneID HPRD None
    RB1 Protein SNAPC1 GeneID HPRD None
    RB1 Protein HDAC3 GeneID HPRD None
    RB1 Protein KDM5A GeneID HPRD None
    RB1 Protein PPP1CC GeneID HPRD None
    RB1 Protein RNF40 GeneID HPRD None
    RB1 Protein HSPA8 GeneID HPRD None
    RB1 Protein EID1 GeneID HPRD None
    RB1 Protein NDC80 GeneID HPRD None
    RB1 Protein BDP1 GeneID HPRD None
    RB1 Protein SPIB GeneID HPRD None
    RB1 Protein FRK GeneID HPRD None
    RB1 Protein TRAP1 GeneID HPRD None
    RB1 Protein PIK3R3 GeneID HPRD None
    RB1 Protein NCOA6 GeneID HPRD None
    RB1 Protein ENC1 GeneID HPRD None
    RB1 Protein BRF1 GeneID HPRD None
    RB1 Protein GTF3C2 GeneID HPRD None
    RB1 Protein TRIP11 GeneID HPRD None
    RB1 Protein RBBP8 GeneID HPRD None
    RB1 Protein CCNA1 GeneID HPRD None
    RB1 Protein CCNT2 GeneID HPRD None
    RB1 Protein USP4 GeneID HPRD None
    RB1 Protein PSMD10 GeneID HPRD None
    RB1 Protein PRKRA GeneID HPRD None
    RB1 Protein CDK6 GeneID HPRD None
    RB1 Protein SMARCA4 GeneID HPRD None
    RB1 Protein CBX4 GeneID HPRD None
    RB1 Protein SNW1 GeneID HPRD None
    RB1 Protein E4F1 GeneID HPRD None
    RB1 Protein RBBP4 GeneID HPRD None
    RB1 Protein RBBP7 GeneID HPRD None
    RB1 Protein RBBP9 GeneID HPRD None
    RB1 Protein MAPK9 GeneID HPRD None
    RB1 Protein MDM4 GeneID HPRD None
    RB1 Protein EP300 GeneID HPRD None
    RB1 Protein MNAT1 GeneID HPRD None
    RB1 Protein CTBP1 GeneID HPRD None
    RB1 Protein SNAPC3 GeneID HPRD None
    RB1 Protein CASP9 GeneID HPRD None
    RB1 Protein PA2G4 GeneID HPRD None
    RB1 Protein RING1 GeneID HPRD None
    RB1 Protein SP3 GeneID HPRD None
    RB1 Protein CASP8 GeneID HPRD None
    RB1 Protein CASP10 GeneID HPRD None
    RB1 Protein CASP7 GeneID HPRD None
    RB1 Protein SMARCB1 GeneID HPRD None
    RB1 Protein CASP6 GeneID HPRD None
    RB1 Protein BAG1 GeneID HPRD None
    RB1 Protein DGKZ GeneID HPRD None
    RB1 Protein SKP2 GeneID HPRD None
    RB1 Protein HDAC1 GeneID HPRD None
    RB1 Protein PRDM2 GeneID HPRD None
    RB1 Protein CEBPE GeneID HPRD None
    RB1 Protein RBBP5 GeneID HPRD None
    RB1 Protein UBTF GeneID HPRD None
    RB1 Protein E2F4 GeneID HPRD None
    RB1 Protein CASP2 GeneID HPRD None
    RB1 Protein CASP3 GeneID HPRD None
    RB1 Protein PURA GeneID HPRD None
    RB1 Protein E2F3 GeneID HPRD None
    RB1 Protein E2F2 GeneID HPRD None
    RB1 Protein ID2 GeneID HPRD None
    RB1 Protein AHR GeneID HPRD None
    RB1 Protein RUNX2 GeneID HPRD None
    RB1 Protein TBP GeneID HPRD None
    RB1 Protein AR GeneID HPRD None
    RB1 Protein TAF1 GeneID HPRD None
    RB1 Protein POLA1 GeneID HPRD None
    RB1 Protein MORF4L2 GeneID HPRD None
    RB1 Protein SUV39H1 GeneID HPRD None
    RB1 Protein TGM2 GeneID HPRD None
    RB1 Protein MYC GeneID HPRD None
    RB1 Protein ABL1 GeneID HPRD None
    RB1 Protein ELF1 GeneID HPRD None
    RB1 Protein E2F1 GeneID HPRD None
    RB1 Protein CEBPB GeneID HPRD None
    RB1 Protein SP1 GeneID HPRD None
    RB1 Protein TMPO GeneID HPRD None
    RB1 Protein RB1 GeneID HPRD None
    RB1 Protein RACK1 GeneID HPRD None
    RB1 Protein PRKCB GeneID HPRD None
    RB1 Protein MAPK1 GeneID HPRD None
    RB1 Protein INS GeneID HPRD None
    RB1 Protein PHB1 GeneID HPRD None
    RB1 Protein SERPINB2 GeneID HPRD None
    RB1 Protein PIK3R1 GeneID HPRD None
    RB1 Protein CCND1 GeneID HPRD None
    RB1 Protein PAX5 GeneID HPRD None
    RB1 Protein PAX2 GeneID HPRD None
    RB1 Protein SPI1 GeneID HPRD None
    RB1 Protein JUN GeneID HPRD None
    RB1 Protein FOS GeneID HPRD None
    RB1 Protein MDM2 GeneID HPRD None
    RB1 Protein RAF1 GeneID HPRD None
    RB1 Protein HMGB1 GeneID HPRD None
    RB1 Protein MYOD1 GeneID HPRD None
    RB1 Protein MCM7 GeneID HPRD None
    RB1 Protein LMNA GeneID HPRD None
    RB1 Protein TOP2A GeneID HPRD None
    RB1 Protein DNMT1 GeneID HPRD None
    RB1 Protein PPIA GeneID HPRD None
    RB1 Protein CCND2 GeneID HPRD None
    RB1 Protein CDK4 GeneID HPRD None
    RB1 Protein ATF2 GeneID HPRD None
    RB1 Protein CDK2 GeneID HPRD None
    RB1 Protein CDC27 GeneID HPRD None
    RB1 Protein CDK1 GeneID HPRD None
    RB1 Protein CDKN1A GeneID HPRD None
    RB1 Protein CEBPD GeneID HPRD None
    RB1 Protein CEBPA GeneID HPRD None
    RB1 Protein CUX1 GeneID HPRD None
    RB1 Protein BRCA1 GeneID HPRD None
    RB1 Protein TFAP2A GeneID HPRD None
    RB1 Protein PML GeneID HPRD None
    RB1 BioGRID L3MBTL2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID L3MBTL1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID FIE GeneID BioGRID Reconstituted Complex; Two-hybrid
    RB1 BioGRID TBP GeneID BioGRID Reconstituted Complex
    RB1 BioGRID TAF1 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
    RB1 BioGRID AATF GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID TRAP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID THOC1 GeneID BioGRID Reconstituted Complex; Two-hybrid
    RB1 BioGRID TRIP11 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID RBBP5 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID MNAT1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID ARNT GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID HBP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID MORF4L1 GeneID BioGRID Affinity Capture-Western; Co-purification; Reconstituted Complex
    RB1 BioGRID ARID3B GeneID BioGRID Reconstituted Complex
    RB1 BioGRID RACK1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CREG1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID PIK3R3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID TGM2 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID SUV39H1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID SNAPC3 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID SNAPC1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID RING1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID RFC1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID PAX6 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID MYOD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID HMGB1 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID FRK GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID E4F1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID CCNT2 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID BAG1 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID TMPO GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID POLA1 GeneID BioGRID Affinity Capture-Western; Co-purification
    RB1 BioGRID VDR GeneID BioGRID Reconstituted Complex
    RB1 BioGRID NFIX GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID Smarca4 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID MRFAP1 GeneID BioGRID Affinity Capture-Western; Co-purification
    RB1 BioGRID PPARG GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID PELP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    RB1 BioGRID TP73 GeneID BioGRID Affinity Capture-Western
    RB1 BioGRID CUX1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID MORF4L2 GeneID BioGRID Reconstituted Complex
    RB1 BioGRID NCOA6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    RB1 BioGRID BCR GeneID BioGRID Affinity Capture-Western
    RB1 Protein UBE2I GeneID BIND RB1 (pRb) interacts with, and is sumoylated by, an unspecified isoform of UBE2I (Ubc9).
    RB1 Protein E1A GeneID BIND RB1 (pRb) interacts with an unspecified isoform of the Adenovirus E1A protein.
    RB1 Protein EID1 GeneID BIND RB1 (pRb) interacts with CRI1 (EID-1).
    RB1 Protein SV40gp6 GeneID BIND pRB interacts with SV40 T antigen.
    RB1 Protein E2F1 GeneID BIND pRB interacts with E2F-1.
    RB1 Protein E2F2 GeneID BIND pRB interacts with E2F-2.
    RB1 Protein KDM5A GeneID BIND pRB interacts with RBP2.
    RB1 Protein ZBTB16 GeneID BIND pRB interacts with PLZF.
    RB1 Protein BGLAP GeneID BIND pRB interacts with OC promoter.
    RB1 Protein BRD8 GeneID BIND pRB interacts with BRD8 promoter.
    RB1 Protein BRD2 GeneID BIND pRB interacts with BRD2 promoter.
    RB1 Protein EID1 GeneID BIND pRB interacts with EID-1.
    RB1 Protein BNC2 GeneID BIND pRB interacts with BAA90908.
    RB1 Protein CASP8 GeneID BIND CASP8 (caspase-8) cleaves RB-1 (hRB) into the p68 form and to a lesser extent the p61 form.
    RB1 Protein CASP6 GeneID BIND CASP6 (caspase-6) cleaves RB-1 (hRB) at the DSID consensus site to produce the p68 form.
    RB1 Protein CASP9 GeneID BIND CASP9 (caspase-9) cleaves RB-1 (hRB) at the LEND consensus site to produce the p76 form.
    RB1 Protein CASP7 GeneID BIND CASP7 (caspase-7) cleaves RB-1 (hRB) at the DEAD and DSID consensus sites to produce the p68, p61 and p48 forms.
    RB1 Protein CASP2 GeneID BIND CASP2 (caspase-2) cleaves RB-1 (hRB) at the DEAD consensus site into the p100 form.
    RB1 Protein CASP3 GeneID BIND CASP3 (caspase-3) cleaves RB-1 (hRB) at the DEAD and DSID consensus sites to produce the p100, p68, p61 and p48 forms.
    RB1 Protein CASP10 GeneID BIND CASP10 (caspase-10) cleaves RB-1 (hRB) at the DSID consensus site to produce the p68 form.
    RB1 Protein HMGB1 GeneID BIND HMGB1 interacts with RB1 (pRB). This interaction was modelled on a demonstrated interaction between rat HMGB1 and human RB1 (pRB).
    RB1 Protein CEBPD GeneID BIND C/EBP-delta interacts with Rb.
    RB1 Protein GTF3C2 GeneID BIND Rb interacts with TFIIIC2
    RB1 Protein HDAC1 GeneID BIND RB interacts with HDAC1.
    RB1 Protein CDKN1A GeneID BIND Rb interacts with the p21 promoter.
    RB1 Protein TYR GeneID BIND Rb interacts with the TYR promoter.
    RB1 Protein RBL1 GeneID BIND Rb interacts with the p107 promoter.
    RB1 Protein MITF GeneID BIND An unspecified isoform of Mitf interacts with Rb.
    RB1 Protein None None BIND The Cyclin E-Cdk2 complex phosphorylates Rb
    RB1 Protein None None BIND The Cyclin B1-Cdc2 complex phosphorylates Rb
    RB1 Protein None None BIND The Cyclin A-Cdk2 complex phosphorylates Rb
    RB1 Protein CDK6 GeneID BIND Cdk6 phosphorylates Rb
    RB1 Protein SKP2 GeneID BIND Skp2 interacts with Rb.
    RB1 Protein MAPK1 GeneID BIND RB1 is phosphorylated by MAPK1. This interaction was modeled on a demonstrated interaction between human KIAA1536 and MAPK1 from an unspecified species.
    RB1 Protein E2F2 GeneID BIND E2F-2 interacts with pRb.
    RB1 Protein E2F2 GeneID BIND E2F1 interacts with pRb.
    RB1 Protein PIK3R3 GeneID BIND Rb interacts with PI3K regulatory subunit p55gamma
    RB1 Protein MDM2 GeneID BIND Rb interacts with Mdm2.
    RB1 Protein E2F1 GeneID BIND pRb interacts with E2F1.
    RB1 Protein CEBPE GeneID BIND Rb interacts with C/EBPepsilon.
    RB1 Protein ATF2 GeneID BIND Rb interacts with ATF2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and ATF2 from an unspecified species.
    RB1 Protein MAPK9 GeneID BIND Rb interacts with JNK2. This interaction was modelled on a demonstrated interaction between Rb from an unspecified species and JNK2 from an unspecified species.
    RB1 Protein BIRC5 GeneID BIND RB1 (pRB) interacts with the BIRC5 (survivin) promoter.
    RB1 Protein ABL1 GeneID BIND Rb interacts with c-Abl
    RB1 Protein RUNX2 GeneID BIND Runx2 interacts with pRb.
    RB1 Protein MDM2 GeneID BIND Rb interacts with MDM2.
    RB1 Protein RBBP7 GeneID BIND The retinoblastoma protein, Rb, interacts with RbAp46.
    RB1 Protein RBBP4 GeneID BIND The retinoblastoma protein 1 (Rb) interacts with RbAp48
    RB1 Protein HDAC1 GeneID BIND The Retinoblastoma protein interacts with Histone Deacetylase 1.
    RB1 Protein BRCA1 GeneID BIND BRCA1 interacts with Rb.
    RB1 Protein NCOA6 GeneID BIND Rb interacts with ASC-2.
    RB1 Protein MCM7 GeneID BIND MCM7 interacts with Rb.
    RB1 Protein PELP1 GeneID BIND PELP1 interacts with pRb.
    RB1 Protein AR GeneID BIND Rb interacts with AR.
    RB1 Protein None None BIND Cyclin E-CDK2 complex interacts with and phosphorylates RB1 (Rb).
    RB1 Protein E2F1 GeneID BIND pRB interacts with E2F1.
    RB1 Protein FRK GeneID BIND pRB interacts with Rak.
    RB1 Protein VEGFA GeneID BIND RB1 (pRB) interacts with the VEGF promoter.
    RB1 Protein EPO GeneID BIND RB1 (pRB) interacts with the EPO gene 3(prime) enhancer.
    RB1 Protein None None BIND CCND1-CDK4 complex interacts with and phosphorylates RB1 (Rb).
    RB1 Protein HIF1A GeneID BIND RB1 (pRB) interacts with HIF1A (HIF-1-alpha).
    RB1 Protein TMPO GeneID BIND Rb interacts with LAP2alpha
    RB1 Protein LMNA GeneID BIND Rb interacts with lamin C
    RB1 Protein MT1G GeneID BIND RB1 interacts with the MT1G promoter.
    RB1 Protein JUN GeneID BIND RB interacts with c-Jun.
    RB1 Protein E2F1 GeneID BIND Rb interacts with E2F
    RB1 Protein SERPINB2 GeneID BIND Rb interacts with PAI-2.
    RB1 Protein CDK6 GeneID BIND CDK6 phosphorylates Rb. This interaction was modeled on a demonstrated interaction between CDK6 and Rb, both from an unspecified species.
    RB1 Protein MDM4 GeneID BIND pRb interacts with MDMX. This interaction was modeled on a demonstrated interaction between mouse MDMX and human pRb.
    RB1 Protein LIN9 GeneID BIND pRb interacts with hMip130/TWIT.
    RB1 Protein LIN54 GeneID BIND pRb interacts with hMip120.
    RB1 Protein LIN37 GeneID BIND pRb interacts with hMip40.
    RB1 Protein RAF1 GeneID BIND Raf-1 interacts with Rb.
    RB1 Protein E2F1 GeneID BIND E2F1 (RBP3) interacts with pRB.
    RB1 Protein PIK3R1 GeneID BIND Rb interacts with p55alpha
    RB1 Protein BDP1 GeneID BIND Rb interacts with TFIIIB90
    RB1 Protein RACK1 GeneID BIND RACK1 interacts with Rb
    RB1 Protein SNAPC1 GeneID BIND Rb interacts with SNAP43
    RB1 Protein SNAPC3 GeneID BIND Rb interacts with SNAP50
    RB1 Protein TBP GeneID BIND Rb interacts with TBP
    RB1 Protein DNMT1 GeneID BIND Rb interacts with hDnmt1.
    RB1 Protein None None BIND A complex consiting of two subunits including cyclin C and cdk3 interacts with Rb.
    RB1 Protein TAF1 GeneID BIND TAFII250 interacts with Rb.
    RB1 Protein CCND1 GeneID BIND Rb interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between Cyclin D1 from mouse and Rb from human.
    RB1 Protein UL122 GeneID BIND IE2 86 interacts with Rb.
    RB1 Protein CDK2 GeneID BIND CDK2 phosphorylates Rb carboxy-terminus.
    RB1 Protein CDK4 GeneID BIND CDK4 phosphorylates Rb carboxy-terminus. This interaction was modelled on a demonstrated interaction between human Rb and mouse CDK4.
    RB1 Protein KDM5A GeneID BIND Rbp2 interacts with Rb. This interaction was modeled on a demonstrated interaction between human Rbp2 and Rb from an unspecified species.
    RB1 Protein PPIA GeneID BIND Rb interacts with CypA.
    RB1 Protein KAT2B GeneID BIND pRb interacts with the acetyltransferase domain of P/CAF.
    RB1 Protein E2F1 GeneID BIND Rb interacts with E2F-1.
    RB1 Protein AATF GeneID BIND Che-1 interacts with Rb.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    RB1 CDKN1A 270 900 712 982 1 2
    RB1 SFTPA1 0 0 321 321 1 1
    RB1 AR 675 650 460 939 1 1
    RB1 GNRH1 0 0 181 181 1 1
    RB1 AURKA 0 0 261 328 1 2
    RB1 FAM208A 192 0 69 232 1 1
    RB1 POU3F1 0 0 66 172 1 1
    RB1 BAX 0 0 234 297 1 2
    RB1 H2AFB1 0 900 0 902 1 1
    RB1 SOHLH2 0 0 57 443 1 1
    RB1 BCR 270 0 108 325 1 1
    RB1 PTPRC 0 0 181 186 1 1
    RB1 FOXA3 94 0 0 173 1 1
    RB1 SOX9 0 0 218 218 1 1
    RB1 SUV420H2 213 0 174 399 1 1
    RB1 ZMYND15 0 0 0 151 1 1
    RB1 CCNB2 0 0 210 384 1 1
    RB1 DDX4 0 0 69 209 1 1
    RB1 HSP90AA1 128 900 294 933 1 2
    RB1 CTBP1 480 900 218 957 1 1
    RB1 C4BPA 0 0 439 439 1 1
    RB1 E2F7 0 0 744 848 1 1
    RB1 TEN1 0 0 53 270 1 1
    RB1 HIST2H2AA3 0 0 181 198 1 1
    RB1 HDAC4 0 0 134 335 1 1
    RB1 DHX57 0 0 0 224 1 1
    RB1 WDR89 0 0 157 156 1 1
    RB1 SP100 0 900 181 914 1 1
    RB1 SOX2 0 0 391 390 1 1
    RB1 CRP 0 0 71 280 1 1
    RB1 ELF2 0 0 0 207 1 1
    RB1 ATF2 486 900 64 953 1 1
    RB1 TP73 486 900 254 962 1 2
    RB1 NCAPG2 0 600 0 825 1 1
    RB1 UBE2E1 0 600 0 620 1 1
    RB1 WHSC1L1 0 0 94 322 1 1
    RB1 ATG13 0 0 95 151 1 2
    RB1 RAD21L1 0 0 0 261 1 1
    RB1 SLC7A3 0 0 0 212 1 1
    RB1 HIST2H2AA 0 0 181 198 1 1
    RB1 MAPK3 156 900 393 946 1 2
    RB1 ACR 0 0 0 242 1 1
    RB1 MMP9 0 0 300 300 1 1
    RB1 PAQR8 0 0 140 272 1 1
    RB1 SQSTM1 0 0 164 165 1 2
    RB1 TFDP1 961 900 400 998 1 1
    RB1 TFAP2D 0 0 0 252 1 1
    RB1 JUNB 0 0 125 278 1 1
    RB1 NIPBL 0 0 63 165 1 1
    RB1 SLC11A2 0 0 0 164 1 1
    RB1 NCOA2 0 0 147 237 1 1
    RB1 RLF 0 0 176 206 1 1
    RB1 TK1 0 0 122 292 1 1
    RB1 CCNA2 870 900 716 996 1 1
    RB1 PRAM1 0 0 375 375 1 1
    RB1 DNTT 0 0 193 218 1 1
    RB1 ZBTB16 462 0 90 601 1 1
    RB1 PIK3CG 0 0 123 212 1 1
    RB1 ERBB4 0 0 206 223 1 1
    RB1 HIC1 0 0 81 176 1 1
    RB1 CYP19A1 0 0 260 260 1 1
    RB1 DNAJA3 0 900 0 900 1 1
    RB1 SERPINB2 486 0 207 575 1 1
    RB1 ACTR3 0 0 0 163 1 1
    RB1 INTS6 0 0 81 178 1 1
    RB1 CDH17 0 0 193 193 1 1
    RB1 DAPK1 0 0 227 243 1 2
    RB1 TAF1 835 900 112 984 1 1
    RB1 ASF1A 0 900 113 919 1 1
    RB1 JUN 486 900 421 967 1 1
    RB1 ASF1B 0 0 0 167 1 1
    RB1 JAG1 0 0 181 196 1 1
    RB1 GTF2F1 0 0 81 255 1 1
    RB1 GRB2 280 0 126 352 1 1
    RB1 ACTR3C 0 0 0 163 1 1
    RB1 KRT1 0 0 272 272 1 1
    RB1 CENPE 0 0 108 177 1 1
    RB1 SMC3 0 0 73 436 1 1
    RB1 SMC1A 0 0 74 423 1 1
    RB1 BMI1 0 0 344 343 1 1
    RB1 ARNT 270 0 112 549 1 2
    RB1 TBL1X 0 0 155 280 1 1
    RB1 CDC25C 0 0 285 372 1 1
    RB1 RING1 270 0 108 321 1 1
    RB1 BTG1 0 0 150 246 1 1
    RB1 HIST1H2BK 0 900 49 902 1 1
    RB1 MOB2 0 0 54 154 1 1
    RB1 ZBTB7A 270 0 49 303 1 1
    RB1 LIN37 0 0 107 307 1 1
    RB1 RUNX3 0 0 170 191 1 1
    RB1 RSBN1 0 0 0 189 1 1
    RB1 NCOA3 0 0 211 269 1 1
    RB1 ENSG00000270024 0 0 75 259 1 1
    RB1 SKA2 0 0 73 188 1 1
    RB1 KRT8 0 0 324 323 1 1
    RB1 MAPK8 270 0 181 422 1 2
    RB1 CBFA2T3 0 0 357 357 1 1
    RB1 NXT1 0 0 123 198 1 1
    RB1 CENPF 0 0 122 301 1 1
    RB1 RPRD1B 151 0 0 203 1 1
    RB1 PTK2 0 0 218 218 1 1
    RB1 PHF8 0 650 0 657 1 1
    RB1 MBTD1 0 0 0 180 1 1
    RB1 MAP2K4 0 0 160 174 1 1
    RB1 BRAF 0 0 233 390 1 1
    RB1 CTDSPL 0 0 321 321 1 1
    RB1 FBLIM1 0 0 0 150 1 1
    RB1 MUT 0 0 176 181 1 1
    RB1 KDM2A 270 0 91 336 1 1
    RB1 DIABLO 0 0 170 169 1 1
    RB1 CHD5 0 0 0 178 1 1
    RB1 PPP2CB 0 900 52 917 1 1
    RB1 CHKA 0 0 306 306 1 1
    RB1 CENPW 0 0 0 207 1 1
    RB1 MIER2 0 0 0 170 1 1
    RB1 TMCO4 0 0 143 274 1 1
    RB1 DICER1 0 0 260 292 1 1
    RB1 PIK3R1 213 0 181 372 1 1
    RB1 TFAP2E 0 0 0 362 1 1
    RB1 HSPA4 0 0 219 224 1 1
    RB1 ETV5 0 0 67 161 1 1
    RB1 GATA4 0 0 134 189 1 2
    RB1 SMARCA2 270 900 170 938 1 1
    RB1 CCNJL 0 0 0 261 1 1
    RB1 PPARA 0 900 197 919 1 1
    RB1 NFYA 0 900 137 910 1 1
    RB1 PDCD4 0 0 155 173 1 1
    RB1 GGA1 0 0 90 230 1 1
    RB1 DGKZ 270 0 483 656 1 1
    RB1 CYCS 0 0 309 317 1 1
    RB1 NWD2 0 0 67 167 1 1
    RB1 CLSPN 0 0 113 173 1 1
    RB1 CDC6 0 0 376 601 1 1
    RB1 HNF1A 0 0 392 392 1 1
    RB1 EGF 0 0 391 390 1 1
    RB1 ENSG00000267318 0 0 0 200 1 1
    RB1 CHD1 0 0 57 166 1 1
    RB1 CDK5 270 0 171 368 1 2
    RB1 EP300 685 900 685 990 1 1
    RB1 PDGFRB 0 0 182 181 1 1
    RB1 LEF1 129 0 178 383 1 1
    RB1 SLBP 0 0 46 186 1 1
    RB1 ROCK1 0 0 135 175 1 1
    RB1 REC8 0 0 0 263 1 1
    RB1 VSX1 0 0 51 161 1 1
    RB1 RABGAP1L 170 0 0 169 1 1
    RB1 BRWD1 0 0 0 158 1 1
    RB1 RNF123 270 0 0 464 1 1
    RB1 BIRC3 0 0 155 175 1 1
    RB1 SMAD3 0 0 210 267 1 1
    RB1 SGK2 0 0 0 200 1 1
    RB1 ALB 0 0 324 323 1 1
    RB1 CDC23 0 600 0 636 1 1
    RB1 CCL2 0 0 164 163 1 2
    RB1 PPP2R1B 0 900 54 901 1 1
    RB1 PMF1 0 0 0 161 1 1
    RB1 SNAI2 0 0 211 211 1 1
    RB1 CASP7 675 0 260 754 1 1
    RB1 CUL1 0 0 202 242 1 1
    RB1 GTF3C2 270 0 66 289 1 1
    RB1 ZYX 0 0 83 188 1 1
    RB1 MAF 0 650 108 674 1 1
    RB1 SMARCE1 0 720 62 726 1 1
    RB1 GLB1 0 0 103 165 1 1
    RB1 COPS3 0 0 57 271 1 1
    RB1 H3F3B 0 0 142 236 1 1
    RB1 GATA1 270 0 135 492 1 1
    RB1 ENSG00000257411 0 0 0 150 1 1
    RB1 WNT1 0 0 134 169 1 1
    RB1 PAX6 270 0 422 567 1 1
    RB1 PPP1CB 128 800 167 868 1 1
    RB1 PNO1 271 0 0 271 1 1
    RB1 ALK 0 0 252 265 1 1
    RB1 ECD 270 0 0 270 1 1
    RB1 TADA2B 0 0 0 222 1 1
    RB1 SIRT6 0 0 143 251 1 1
    RB1 DUT 0 900 0 904 1 1
    RB1 HIST1H2BO 0 900 0 900 1 1
    RB1 IDH1 0 0 234 250 1 1
    RB1 SYCP1 0 0 57 314 1 1
    RB1 CDH1 0 0 470 470 1 1
    RB1 CDK16 0 0 66 315 1 1
    RB1 PDGFRA 0 0 216 330 1 1
    RB1 BUB1B 0 0 241 335 1 1
    RB1 PFKFB2 0 0 56 155 1 1
    RB1 RMDN3 0 0 0 165 1 1
    RB1 CUL2 0 0 363 375 1 1
    RB1 RBL1 0 800 861 912 1 1
    RB1 RAF1 875 900 231 990 1 2
    RB1 ADAMTS1 0 0 306 306 1 1
    RB1 ANKS1A 170 0 0 192 1 1
    RB1 CDKN2AIP 0 0 241 240 1 1
    RB1 NCOR2 0 0 180 382 1 1
    RB1 CDC26 0 600 0 600 1 1
    RB1 CHAF1B 0 0 0 208 1 1
    RB1 KRT10 0 0 459 459 1 1
    RB1 HDAC2 753 800 341 969 1 1
    RB1 SATB2 0 0 202 202 1 1
    RB1 TGM2 270 0 428 565 1 1
    RB1 PRPSAP1 0 0 135 265 1 1
    RB1 CTNNA1 0 0 161 179 1 1
    RB1 MDM2 881 900 875 998 1 1
    RB1 TP53 486 900 819 990 1 2
    RB1 PPP1CC 128 800 108 864 1 1
    RB1 EGFR 0 0 510 520 1 1
    RB1 CFLAR 0 0 136 155 1 1
    RB1 MAP3K13 0 0 0 229 1 1
    RB1 ATP2C1 0 0 124 155 1 1
    RB1 NEDD8 0 0 103 172 1 1
    RB1 SLC2A1 0 0 155 154 1 1
    RB1 FGFR3 0 0 262 262 1 1
    RB1 ZNF618 0 0 0 160 1 1
    RB1 KRT5 0 0 392 392 1 1
    RB1 BRF1 675 0 0 727 1 1
    RB1 AATF 486 900 66 947 1 1
    RB1 CENPA 0 0 150 162 1 1
    RB1 PHF7 0 0 0 159 1 1
    RB1 NCOA1 0 0 851 861 1 1
    RB1 HBEGF 0 0 130 183 1 1
    RB1 RFC3 0 0 53 258 1 1
    RB1 TBRG1 0 0 0 253 1 1
    RB1 CCNI 0 0 0 252 1 1
    RB1 CDH2 0 0 323 323 1 1
    RB1 HDAC6 0 0 150 284 1 2
    RB1 APAF1 0 0 294 336 1 1
    RB1 HIST1H1B 0 900 0 900 1 1
    RB1 JAK2 0 0 184 198 1 1
    RB1 PSMD10 835 0 744 961 1 1
    RB1 LIMD1 0 0 480 539 1 1
    RB1 PPARD 0 0 116 183 1 1
    RB1 CDH3 0 0 293 293 1 1
    RB1 KLF10 0 0 63 168 1 1
    RB1 NR4A1 0 0 63 195 1 1
    RB1 ENC1 486 0 427 699 1 1
    RB1 MYBL1 0 0 48 282 1 1
    RB1 STMN4 0 0 49 424 1 1
    RB1 BRD4 265 0 230 433 1 1
    RB1 PIK3R3 270 0 66 301 1 1
    RB1 DVL1 128 0 72 176 1 1
    RB1 TBX5 0 0 0 177 1 1
    RB1 CMC1 0 0 0 373 1 1
    RB1 AP5M1 0 0 95 171 1 1
    RB1 RICTOR 0 0 120 165 1 2
    RB1 SF3A2 0 0 54 241 1 1
    RB1 WWTR1 0 650 94 819 1 1
    RB1 CBX4 486 900 96 949 1 1
    RB1 TOP1 0 0 166 192 1 1
    RB1 RAD18 0 0 0 283 1 1
    RB1 PURA 270 0 0 270 1 1
    RB1 WNT5A 0 0 146 181 1 1
    RB1 CBX5 486 0 139 583 1 1
    RB1 CLOCK 0 0 53 393 1 2
    RB1 DSN1 0 0 48 214 1 1
    RB1 IFNA1 0 0 205 205 1 1
    RB1 CCNH 0 0 241 290 1 1
    RB1 MAD2L1 0 0 108 262 1 1
    RB1 SLC1A3 0 0 74 176 1 1
    RB1 PPRC1 0 0 561 571 1 1
    RB1 SNAPC1 270 0 0 315 1 1
    RB1 PPP5C 0 0 0 163 1 1
    RB1 POLR2G 0 0 46 202 1 1
    RB1 PPARGC1A 0 0 181 241 1 1
    RB1 PRB4 0 0 725 725 1 1
    RB1 PRB1 0 0 643 643 1 1
    RB1 CKS2 0 0 0 255 1 1
    RB1 GLTSCR1 0 720 0 748 1 1
    RB1 NFIX 270 0 90 319 1 1
    RB1 RFC1 270 0 396 609 1 1
    RB1 KIF20B 0 0 0 164 1 1
    RB1 RB1CC1 0 0 357 357 1 2
    RB1 CDC5L 0 0 57 237 1 1
    RB1 CDKN2D 0 0 405 421 1 1
    RB1 TOP2A 270 0 134 401 1 1
    RB1 CHN2 170 0 0 188 1 1
    RB1 TCF3 270 0 123 406 1 1
    RB1 AREG 0 0 350 349 1 1
    RB1 USP39 0 0 60 313 1 1
    RB1 KRT4 0 0 245 244 1 1
    RB1 STK11 0 0 247 263 1 2
    RB1 BRCA1 731 0 683 913 1 1
    RB1 LEMD3 0 0 136 163 1 1
    RB1 CCNT1 0 0 61 173 1 1
    RB1 CHGA 0 0 161 205 1 1
    RB1 MAGEA11 270 0 69 303 1 1
    RB1 L3MBTL4 0 0 0 163 1 1
    RB1 VPS39 0 0 97 642 1 1
    RB1 HIST1H2BH 0 900 0 900 1 1
    RB1 CASP10 270 0 117 343 1 1
    RB1 RCOR3 0 0 0 334 1 1
    RB1 PAQR7 0 0 213 378 1 1
    RB1 POLR2A 0 0 108 217 1 1
    RB1 GTF2A1L 0 0 74 154 1 1
    RB1 AGAP2 0 0 134 188 1 1
    RB1 TRIP12 0 0 0 327 1 1
    RB1 SIRT2 0 0 181 205 1 2
    RB1 DGCR8 0 0 297 297 1 1
    RB1 CREBBP 0 900 263 951 1 1
    RB1 STAM2 0 0 0 165 1 1
    RB1 POU3F3 0 0 64 170 1 1
    RB1 ANAPC16 0 600 0 600 1 1
    RB1 BCL11B 0 0 219 248 1 1
    RB1 SDHB 0 0 150 237 1 1
    RB1 CREB1 0 0 261 332 1 1
    RB1 HIST2H2AC 0 900 181 916 1 1
    RB1 WWP1 0 0 0 157 1 1
    RB1 PNPO 0 0 0 171 1 1
    RB1 APC 0 0 253 307 1 1
    RB1 GAPDH 0 0 518 518 1 2
    RB1 ESPL1 0 0 88 278 1 1
    RB1 FGFR2 0 0 219 219 1 1
    RB1 ENO1 0 0 124 158 1 1
    RB1 PML 270 900 144 932 1 1
    RB1 MAP2K7 0 0 414 466 1 1
    RB1 HIST4H4 273 0 294 472 1 1
    RB1 ABL1 835 900 210 986 1 1
    RB1 TCF7L2 0 0 74 235 1 1
    RB1 HDAC10 0 0 60 208 1 1
    RB1 CASP6 270 0 108 336 1 1
    RB1 ZIC1 0 0 92 161 1 1
    RB1 CIAPIN1 0 0 69 162 1 1
    RB1 JADE2 0 0 0 162 1 1
    RB1 BUB1 0 0 213 310 1 1
    RB1 PIWIL2 0 0 0 192 1 1
    RB1 CLNK 280 0 0 280 1 1
    RB1 CDH13 0 0 267 267 1 1
    RB1 RELA 0 0 218 218 1 1
    RB1 PLK4 0 0 101 190 1 1
    RB1 BNC2 213 0 0 213 1 1
    RB1 KAT6A 0 0 150 168 1 1
    RB1 HIRA 0 900 0 902 1 1
    RB1 NFKB1 0 0 120 203 1 1
    RB1 EGR1 0 0 180 210 1 1
    RB1 HRAS 0 0 600 625 1 1
    RB1 MYF5 0 0 144 191 1 1
    RB1 CTNNB1 0 0 469 511 1 1
    RB1 MSH6 0 0 150 551 1 1
    RB1 MRFAP1 487 0 0 502 1 1
    RB1 SMC2 0 600 0 802 1 1
    RB1 ORC1 312 0 141 567 1 1
    RB1 TGFBRAP1 0 0 0 157 1 1
    RB1 BAZ1A 0 0 52 204 1 1
    RB1 VRK1 0 0 95 170 1 1
    RB1 TRIM27 270 0 279 452 1 1
    RB1 NEDD4 0 0 72 184 1 2
    RB1 ORC3 0 0 0 252 1 1
    RB1 BAG3 0 0 94 218 1 2
    RB1 RPL30 0 0 0 187 1 1
    RB1 CTSL 0 0 310 309 1 1
    RB1 FSHB 0 0 294 294 1 1
    RB1 PAX2 270 0 439 604 1 1
    RB1 KLK3 0 0 213 213 1 1
    RB1 CXCL8 0 0 262 262 1 1
    RB1 L3MBTL1 270 0 0 362 1 1
    RB1 SUMO2 0 0 156 200 1 1
    RB1 CHD1L 0 0 0 188 1 1
    RB1 NPAS2 0 0 0 258 1 1
    RB1 TCF20 0 0 72 186 1 1
    RB1 DCXR 0 0 0 212 1 1
    RB1 IGFBP7 0 0 167 167 1 1
    RB1 TBL1XR1 0 0 54 194 1 1
    RB1 PIK3C3 0 0 82 175 1 2
    RB1 BRWD3 0 0 0 158 1 1
    RB1 ETS2 0 0 155 211 1 1
    RB1 MAPRE1 0 0 63 152 1 1
    RB1 PPP4C 0 0 45 166 1 1
    RB1 PPP1R26 270 0 398 541 1 1
    RB1 BCL2L2-PABPN1 0 0 123 246 1 1
    RB1 ELAVL3 0 0 155 154 1 1
    RB1 STAT1 0 0 181 181 1 1
    RB1 ARAF 0 0 138 218 1 1
    RB1 HIST1H4F 0 0 437 445 1 1
    RB1 JARID2 0 0 113 272 1 1
    RB1 E2F2 870 900 861 998 1 1
    RB1 RAD23A 0 0 0 195 1 1
    RB1 SGOL1 0 0 57 183 1 1
    RB1 RAD51 0 0 264 301 1 1
    RB1 MTOR 0 0 391 452 1 2
    RB1 SUV420H1 0 0 107 239 1 1
    RB1 CMTM5 0 0 68 210 1 1
    RB1 SLC11A1 0 0 0 164 1 1
    RB1 XRCC5 0 0 108 235 1 1
    RB1 PBRM1 0 0 139 215 1 1
    RB1 EHBP1L1 0 0 67 154 1 1
    RB1 ZFAT 0 0 53 246 1 1
    RB1 FABP4 0 0 119 216 1 1
    RB1 CREG1 270 0 47 319 1 1
    RB1 SFN 0 0 244 243 1 1
    RB1 HIST2H4A 0 0 294 304 1 1
    RB1 CUL3 0 0 123 167 1 1
    RB1 CHUK 0 0 166 214 1 1
    RB1 STAM 0 0 431 473 1 1
    RB1 RBL2 0 800 519 906 1 1
    RB1 HAT1 0 0 81 186 1 1
    RB1 WNT2 0 0 74 187 1 1
    RB1 GLTSCR1L 0 720 0 720 1 1
    RB1 DHFR 0 0 284 295 1 1
    RB1 FBXO5 0 0 150 168 1 1
    RB1 UBE2L6 0 0 0 174 1 1
    RB1 MT-CO2 0 0 66 165 1 1
    RB1 HIST3H3 0 900 44 902 1 1
    RB1 DNAJA2 270 0 0 275 1 1
    RB1 HDAC1 913 900 961 999 1 2
    RB1 RRM2 0 0 193 296 1 1
    RB1 PCGF3 172 0 0 171 1 1
    RB1 BRF2 0 0 0 186 1 1
    RB1 TMEM115 0 0 193 193 1 1
    RB1 POLA2 0 650 0 702 1 1
    RB1 KIAA1524 0 0 134 153 1 1
    RB1 EIF3CL 0 0 0 168 1 1
    RB1 JADE1 0 0 0 162 1 1
    RB1 AFP 0 0 151 150 1 1
    RB1 CDC27 486 600 66 835 1 1
    RB1 NFIB 0 0 123 224 1 1
    RB1 DAXX 0 0 218 237 1 1
    RB1 NCAPG 0 0 62 209 1 1
    RB1 PRMT2 270 0 0 361 1 1
    RB1 NOTCH2 0 0 166 181 1 1
    RB1 ZWILCH 0 0 0 161 1 1
    RB1 DIRAS3 0 0 113 168 1 2
    RB1 TIMELESS 0 0 67 308 1 1
    RB1 HELLS 0 0 67 210 1 1
    RB1 PPIA 270 0 107 327 1 1
    RB1 PSMC4 270 0 0 285 1 1
    RB1 SETD1B 0 0 416 510 1 1
    RB1 ALDH1A1 0 0 135 165 1 1
    RB1 STXBP1 0 0 0 158 1 1
    RB1 WEE1 114 0 300 521 1 1
    RB1 PHIP 0 0 0 158 1 1
    RB1 PHB 737 0 116 757 1 1
    RB1 MET 0 0 302 314 1 1
    RB1 PIK3CB 0 0 91 193 1 1
    RB1 CDKN2B 0 0 517 530 1 1
    RB1 PMAIP1 0 0 235 235 1 1
    RB1 PEX3 0 0 46 373 1 2
    RB1 NAB2 0 0 193 193 1 1
    RB1 RFC5 129 0 77 193 1 1
    RB1 PPP1R3A 0 0 53 646 1 1
    RB1 CDT1 0 0 208 404 1 1
    RB1 JADE3 0 0 0 162 1 1
    RB1 TWIST1 0 0 200 268 1 1
    RB1 HEY2 0 0 96 235 1 1
    RB1 FOS 462 0 341 710 1 1
    RB1 NELFB 0 0 0 156 1 1
    RB1 PTPN11 0 0 120 204 1 1
    RB1 PDX1 0 0 0 233 1 1
    RB1 AJUBA 0 0 134 480 1 1
    RB1 LMO2 270 0 391 536 1 1
    RB1 SMYD2 270 0 136 434 1 1
    RB1 BTRC 0 0 170 254 1 1
    RB1 E2F1 998 900 988 999 1 1
    RB1 TOP2B 0 0 664 693 1 1
    RB1 NRAS 0 0 325 390 1 1
    RB1 NANOS2 0 0 49 369 1 1
    RB1 CDK9 839 0 693 951 1 1
    RB1 NANOS1 0 0 0 202 1 1
    RB1 FOXO1 94 0 293 344 1 2
    RB1 EPAS1 0 0 0 413 1 2
    RB1 RCOR1 0 0 113 337 1 1
    RB1 AKT3 0 0 189 203 1 1
    RB1 RALA 0 0 112 167 1 1
    RB1 KDM5B 675 0 242 758 1 1
    RB1 NUMA1 0 0 441 441 1 1
    RB1 RARA 0 0 167 342 1 1
    RB1 TBX21 0 0 0 152 1 1
    RB1 SLC37A3 0 0 0 173 1 1
    RB1 NCAM1 0 0 155 154 1 1
    RB1 SKIL 270 0 0 270 1 1
    RB1 RPS6KA1 0 0 180 179 1 1
    RB1 STMN1 0 0 171 289 1 1
    RB1 LIG1 0 0 76 273 1 1
    RB1 MAP3K12 0 0 0 229 1 1
    RB1 ARID1A 0 720 259 786 1 1
    RB1 ISG15 0 0 46 154 1 1
    RB1 EHBP1 0 0 96 219 1 1
    RB1 CHD3 0 0 67 200 1 1
    RB1 ACTR3B 0 0 0 163 1 1
    RB1 HSPB1 0 0 158 179 1 1
    RB1 GLI1 0 0 218 247 1 1
    RB1 RBBP9 486 0 0 499 1 1
    RB1 COL22A1 0 0 91 183 1 1
    RB1 DYRK1A 508 0 81 579 1 1
    RB1 RCBTB2 0 0 146 235 1 1
    RB1 TGFBR1 0 0 134 194 1 1
    RB1 SP3 213 900 74 923 1 1
    RB1 TP63 0 0 193 249 1 2
    RB1 HIPK2 0 0 113 162 1 1
    RB1 PCNA 0 900 184 934 1 1
    RB1 TBX19 0 0 0 152 1 1
    RB1 SMC1B 0 0 0 402 1 1
    RB1 ATG5 0 0 155 154 1 2
    RB1 WNT3A 0 0 124 160 1 1
    RB1 PPP5D1 0 0 0 163 1 1
    RB1 ACTL6B 0 720 82 744 1 1
    RB1 ORC2 0 0 69 430 1 1
    RB1 RCVRN 0 0 156 155 1 1
    RB1 EHMT1 0 0 62 283 1 1
    RB1 PPP1CA 799 800 285 973 1 1
    RB1 HMGB1 270 0 81 408 1 2
    RB1 RBBP4 874 900 382 995 1 1
    RB1 RIF1 0 0 0 301 1 1
    RB1 LZTR1 0 0 56 156 1 1
    RB1 GATA2 0 0 123 175 1 1
    RB1 SMARCD2 0 720 0 726 1 1
    RB1 T 0 0 0 152 1 1
    RB1 SMARCA4 870 720 828 993 1 1
    RB1 SIRT1 487 900 262 960 1 2
    RB1 MCL1 0 0 323 379 1 2
    RB1 KIF13B 0 0 0 155 1 1
    RB1 HIST1H2AD 0 900 0 902 1 1
    RB1 SPI1 297 900 108 931 1 1
    RB1 TP53BP1 800 0 257 894 1 1
    RB1 UBTF 486 0 102 535 1 1
    RB1 CBX1 270 0 97 379 1 1
    RB1 HIST1H4A 0 0 294 304 1 1
    RB1 UBA52 0 900 0 900 1 1
    RB1 TP53BP2 0 0 141 151 1 1
    RB1 SREBF1 0 0 123 156 1 2
    RB1 UCP1 0 0 155 162 1 1
    RB1 MGEA5 0 0 388 399 1 1
    RB1 MAPK14 839 900 193 986 1 1
    RB1 ENSG00000258947 0 0 261 261 1 1
    RB1 LMNB2 0 0 253 252 1 1
    RB1 TIMP3 0 0 171 171 1 1
    RB1 MSH3 0 0 0 159 1 1
    RB1 NFKBIA 0 0 231 251 1 1
    RB1 PHF6 0 0 0 159 1 1
    RB1 BMP4 0 0 156 155 1 1
    RB1 TCF4 0 0 67 171 1 1
    RB1 ATAD2B 0 0 54 155 1 1
    RB1 WT1 0 0 296 322 1 1
    RB1 KIAA0226 0 0 0 161 1 1
    RB1 MLLT6 0 0 0 174 1 1
    RB1 MYOD1 486 0 422 690 1 1
    RB1 PI4KB 0 0 76 170 1 1
    RB1 UBN1 0 900 55 904 1 1
    RB1 EIF3C 0 0 0 168 1 1
    RB1 NEK7 0 0 0 180 1 1
    RB1 NCOA6 270 0 0 270 1 1
    RB1 PTEN 0 0 558 611 1 2
    RB1 HECW2 0 0 73 199 1 1
    RB1 ARID2 0 0 113 154 1 1
    RB1 VEGFA 0 0 393 392 1 1
    RB1 NFIA 0 0 154 250 1 1
    RB1 KDM5C 0 0 173 222 1 1
    RB1 MAPK7 0 0 123 165 1 1
    RB1 COL1A1 0 900 95 907 1 1
    RB1 RBPJ 0 0 210 348 1 1
    RB1 CHD4 0 0 167 296 1 1
    RB1 GFAP 0 0 245 244 1 2
    RB1 TACC2 0 0 75 561 1 1
    RB1 CDK7 0 0 244 243 1 1
    RB1 BTG2 0 0 123 222 1 1
    RB1 IKZF1 0 0 120 175 1 1
    RB1 ORC5 0 0 46 269 1 1
    RB1 ACTG1 0 0 135 171 1 1
    RB1 RECQL4 0 0 82 247 1 1
    RB1 HTR2B 0 0 305 305 1 1
    RB1 TRAT1 0 0 150 172 1 1
    RB1 MCM8 0 0 0 227 1 1
    RB1 TJP1 0 0 204 204 1 1
    RB1 TGFBR2 0 0 172 186 1 1
    RB1 CDH11 0 0 129 220 1 1
    RB1 BAZ2B 0 0 49 163 1 1
    RB1 RET 0 0 206 315 1 1
    RB1 RAD23B 0 0 55 207 1 1
    RB1 PLEKHA7 0 0 0 157 1 1
    RB1 LIN9 486 0 497 897 1 1
    RB1 POLE2 0 0 0 183 1 1
    RB1 SHC1 128 0 155 231 1 1
    RB1 ATM 0 0 464 516 1 1
    RB1 EZR 0 0 113 249 1 1
    RB1 TUBGCP2 0 0 0 243 1 1
    RB1 HIST1H1C 0 900 56 901 1 1
    RB1 MRE11A 0 0 155 233 1 1
    RB1 AXIN1 0 0 217 252 1 1
    RB1 IDH2 0 0 170 176 1 1
    RB1 CCND1 932 900 720 998 1 1
    RB1 SRPR 0 0 74 190 1 1
    RB1 ANAPC7 0 600 0 624 1 1
    RB1 RRM2B 0 0 120 232 1 1
    RB1 TACC3 0 0 90 166 1 1
    RB1 ACTN1 0 0 0 153 1 1
    RB1 UBE2I 270 0 162 383 1 1
    RB1 MGA 0 0 0 393 1 1
    RB1 TOPBP1 0 0 134 161 1 1
    RB1 L3MBTL2 270 0 0 363 1 1
    RB1 HGNC:9979 273 0 0 273 1 1
    RB1 DMTF1 0 0 57 235 1 1
    RB1 KAT2B 486 0 234 605 1 1
    RB1 OLIG2 0 0 166 198 1 1
    RB1 HEY1 0 0 173 173 1 1
    RB1 HIST2H2BE 0 900 230 919 1 1
    RB1 PPP2CA 0 900 50 916 1 1
    RB1 PRKDC 0 0 166 250 1 2
    RB1 EIF4E 0 0 181 181 1 1
    RB1 NDC80 213 0 136 646 1 1
    RB1 CLK1 0 0 48 196 1 1
    RB1 ARID4A 836 0 329 891 1 1
    RB1 UBB 0 900 81 915 1 1
    RB1 PECAM1 0 0 203 203 1 1
    RB1 CCNK 0 0 52 154 1 1
    RB1 CCNE1 870 900 517 995 1 1
    RB1 MOB3A 0 0 120 196 1 1
    RB1 KIF23 0 0 47 170 1 1
    RB1 HINFP 0 0 386 400 1 1
    RB1 SMYD4 0 0 0 151 1 1
    RB1 HIST2H4B 0 0 294 304 1 1
    RB1 MDK 0 0 67 154 1 1
    RB1 TUBA1A 189 0 0 210 1 1
    RB1 HELZ 130 0 0 157 1 1
    RB1 GNB2L1 270 900 496 960 1 1
    RB1 E2F8 0 0 735 843 1 1
    RB1 PSMA7 270 0 56 281 1 1
    RB1 SFMBT2 0 0 0 163 1 1
    RB1 UAP1 0 0 88 182 1 1
    RB1 KLF9 0 0 699 710 1 1
    RB1 PPM1H 0 0 0 185 1 1
    RB1 C11orf30 0 0 70 169 1 1
    RB1 POU2F1 0 0 69 168 1 1
    RB1 CCNT2 270 0 0 362 1 1
    RB1 VCL 0 0 195 212 1 1
    RB1 MUTYH 0 0 57 179 1 1
    RB1 NRIP1 0 0 171 184 1 1
    RB1 TTC23 0 0 0 181 1 1
    RB1 CD44 0 0 267 267 1 1
    RB1 ARNT2 0 0 57 314 1 1
    RB1 CASP2 213 0 81 263 1 1
    RB1 STAG1 0 0 0 315 1 1
    RB1 HDC 0 0 434 434 1 1
    RB1 SMARCD1 0 720 0 726 1 1
    RB1 CDK12 0 0 77 273 1 1
    RB1 SNAP25 0 0 53 167 1 1
    RB1 LTBP4 0 0 46 208 1 1
    RB1 SUV39H2 0 0 93 301 1 1
    RB1 IGF1 0 0 293 293 1 1
    RB1 ANAPC2 270 600 0 705 1 1
    RB1 MAPK1 213 900 283 941 1 2
    RB1 PPP2R1A 0 900 0 901 1 1
    RB1 SYNE1 0 0 137 187 1 1
    RB1 CCND3 677 900 503 989 1 1
    RB1 NEDD4L 0 0 49 164 1 1
    RB1 GADD45A 0 0 210 210 1 1
    RB1 TUBGCP6 0 0 0 301 1 1
    RB1 FOXK2 201 0 0 215 1 1
    RB1 PPEF2 0 0 0 163 1 1
    RB1 FGF2 0 0 274 274 1 1
    RB1 KMT2A 0 0 123 236 1 1
    RB1 PLEKHA4 270 0 0 270 1 1
    RB1 CDK17 0 0 0 374 1 1
    RB1 BCL2A1 0 0 118 191 1 1
    RB1 HIST1H4H 0 0 294 304 1 1
    RB1 PTCH1 0 0 202 275 1 1
    RB1 AXIN2 0 0 140 168 1 1
    RB1 NCAPD3 0 600 477 914 1 1
    RB1 CD34 0 0 207 207 1 1
    RB1 PSMC1 0 800 0 803 1 1
    RB1 PRKRA 213 0 0 213 1 1
    RB1 SMC6 0 0 0 233 1 1
    RB1 ZNF521 0 650 60 669 1 1
    RB1 HIST1H2BN 0 900 0 900 1 1
    RB1 CREM 0 0 60 280 1 1
    RB1 CHTF18 0 0 0 178 1 1
    RB1 EP400NL 0 0 148 232 1 1
    RB1 AXL 0 0 135 181 1 1
    RB1 RBBP5 270 0 637 749 1 1
    RB1 POLA1 270 650 81 886 1 1
    RB1 TYMS 0 0 213 251 1 1
    RB1 KRT18 0 0 155 154 1 1
    RB1 EIF4EBP1 0 0 320 362 1 1
    RB1 CYLD 0 0 157 171 1 1
    RB1 HMGA1 0 900 90 915 1 1
    RB1 EHD1 0 0 47 372 1 1
    RB1 PHGDH 0 0 218 231 1 1
    RB1 GJA1 0 0 142 160 1 1
    RB1 PPP3CA 0 0 0 163 1 1
    RB1 GALNT12 179 0 0 179 1 1
    RB1 BCL6 0 0 120 161 1 1
    RB1 SDHD 0 0 0 211 1 1
    RB1 DROSHA 0 0 181 207 1 1
    RB1 E2F4 870 900 955 999 1 1
    RB1 KMT2D 0 0 209 312 1 1
    RB1 CDK8 0 0 147 166 1 1
    RB1 SKI 270 0 0 270 1 1
    RB1 ENSG00000279392 0 0 63 193 1 1
    RB1 FAS 128 0 108 194 1 2
    RB1 CDK18 0 0 0 297 1 1
    RB1 SUMO1 0 0 207 248 1 1
    RB1 RBAK 270 0 370 564 1 1
    RB1 FAN1 0 0 0 301 1 1
    RB1 CA9 0 0 140 168 1 1
    RB1 HIST1H4C 270 0 299 474 1 1
    RB1 SPIB 213 0 0 213 1 1
    RB1 WEE2 0 0 0 289 1 1
    RB1 UBR1 0 0 0 159 1 1
    RB1 PRKCD 0 0 186 186 1 2
    RB1 USP7 270 0 105 339 1 1
    RB1 CLK4 0 0 0 152 1 1
    RB1 ARID3B 270 0 0 422 1 1
    RB1 PPP2R3B 0 900 47 903 1 1
    RB1 TMEM37 0 0 249 248 1 1
    RB1 TGFB1 0 0 211 211 1 1
    RB1 ESD 0 0 446 466 1 1
    RB1 PIK3C2A 0 0 62 189 1 2
    RB1 DDB1 0 0 125 178 1 1
    RB1 STAT5B 0 0 171 171 1 1
    RB1 NKX3-1 0 0 142 247 1 1
    RB1 YY1 270 0 208 419 1 1
    RB1 HMMR 0 0 143 161 1 1
    RB1 CHML 0 0 0 189 1 1
    RB1 KDR 0 0 181 181 1 2
    RB1 SKP1 0 0 404 413 1 1
    RB1 HIST1H2BJ 0 900 54 902 1 1
    RB1 MGST1 0 0 0 186 1 1
    RB1 PRIM2 0 650 57 703 1 1
    RB1 H2AFJ 0 900 0 902 1 1
    RB1 PRH1 0 0 724 724 1 1
    RB1 HIST1H4D 0 0 294 304 1 1
    RB1 PRDM2 486 0 134 574 1 1
    RB1 HNF4A 0 0 231 230 1 1
    RB1 POU4F1 0 0 81 154 1 1
    RB1 TP53INP1 0 0 98 154 1 2
    RB1 S100A6 0 0 887 887 1 1
    RB1 HTR2A 0 0 310 309 1 1
    RB1 ORC6 0 0 74 235 1 1
    RB1 HARS2 0 0 0 243 1 1
    RB1 CDKN3 0 0 518 536 1 1
    RB1 LDB2 0 0 0 388 1 1
    RB1 SIM1 0 0 57 185 1 1
    RB1 PKMYT1 0 0 0 289 1 1
    RB1 CCNO 0 0 0 252 1 1
    RB1 MPHOSPH8 0 0 0 192 1 1
    RB1 SIN3B 0 0 68 250 1 1
    RB1 CDC42 0 0 182 204 1 1
    RB1 IGHMBP2 0 0 0 168 1 1
    RB1 BGLAP 0 900 150 911 1 1
    RB1 THOC1 270 0 0 270 1 1
    RB1 ITGA6 0 0 194 194 1 1
    RB1 FOXO3 275 0 288 483 1 2
    RB1 ZNF541 0 0 0 240 1 1
    RB1 CBFB 0 650 0 687 1 1
    RB1 BBOX1 0 0 136 155 1 1
    RB1 VSX2 0 0 167 289 1 1
    RB1 TCF7L1 0 0 44 210 1 1
    RB1 PARP1 0 0 448 462 1 2
    RB1 RHOA 0 0 181 203 1 1
    RB1 ETV4 0 0 95 173 1 1
    RB1 HSPA8 270 0 444 580 1 2
    RB1 UBE2L3 0 0 63 193 1 1
    RB1 GTF2H1 271 0 45 303 1 1
    RB1 KDM1A 270 0 167 386 1 1
    RB1 ZNF622 0 0 0 226 1 1
    RB1 PIWIL1 0 0 95 498 1 1
    RB1 HIST1H2BL 0 900 0 900 1 1
    RB1 GMEB1 0 0 0 165 1 1
    RB1 HIST1H1D 0 900 67 902 1 1
    RB1 SETMAR 0 0 0 261 1 1
    RB1 ESR2 0 0 519 537 1 1
    RB1 SCML4 0 0 70 188 1 1
    RB1 ZEB1 0 0 240 257 1 1
    RB1 SIRT7 0 0 147 172 1 1
    RB1 CCT4 0 0 96 162 1 1
    RB1 POU3F4 0 0 0 150 1 1
    RB1 WDR38 0 0 0 186 1 1
    RB1 CEBPE 270 0 0 282 1 1
    RB1 SETDB1 0 0 88 192 1 1
    RB1 PTGDR 0 900 67 902 1 1
    RB1 PAX8 270 0 155 408 1 1
    RB1 FOSL1 0 0 170 202 1 1
    RB1 FBXW7 0 0 285 405 1 1
    RB1 NPAT 0 0 210 210 1 1
    RB1 MYO9A 0 0 81 210 1 1
    RB1 HPGDS 0 0 195 195 1 1
    RB1 SETD1A 0 0 134 273 1 1
    RB1 CEBPA 678 900 236 974 1 1
    RB1 WRN 0 0 143 254 1 1
    RB1 NEUROD1 0 0 140 267 1 1
    RB1 PTCH2 0 0 47 151 1 1
    RB1 SUV39H1 486 900 438 975 1 1
    RB1 SETBP1 0 0 66 200 1 1
    RB1 ASH1L 0 0 62 178 1 1
    RB1 TUBGCP3 0 0 57 313 1 1
    RB1 FOXG1 0 0 155 185 1 1
    RB1 ACTB 0 0 529 548 1 1
    RB1 INS 463 0 325 622 1 1
    RB1 GTSE1 0 0 82 150 1 1
    RB1 DNMT1 675 900 669 999 1 1
    RB1 TCEAL1 0 0 142 157 1 1
    RB1 MCM5 0 0 170 567 1 1
    RB1 KMT2C 0 0 168 274 1 1
    RB1 SIRT3 0 0 164 189 1 2
    RB1 PROM1 0 0 182 181 1 1
    RB1 ROS1 0 0 142 245 1 1
    RB1 KEAP1 0 0 156 174 1 2
    RB1 PAX5 270 0 150 402 1 1
    RB1 B2M 0 0 167 167 1 1
    RB1 MPND 0 540 0 550 1 1
    RB1 HIST1H4J 0 0 294 304 1 1
    RB1 GLI3 0 0 141 174 1 1
    RB1 PHF21A 0 0 90 220 1 1
    RB1 CHEK1 270 0 402 554 1 1
    RB1 PRPSAP2 0 0 0 186 1 1
    RB1 ULK2 0 0 75 200 1 2
    RB1 CDC20 0 0 219 392 1 1
    RB1 CAV1 0 0 205 205 1 1
    RB1 SRF 0 0 96 234 1 1
    RB1 HSPA1A 0 900 0 900 1 1
    RB1 CALB1 0 0 134 152 1 1
    RB1 BCL2L11 0 0 368 368 1 1
    RB1 TSC1 0 0 47 183 1 2
    RB1 HNRNPA1 0 0 142 157 1 1
    RB1 KIF11 0 0 62 358 1 1
    RB1 FRRS1 0 0 0 157 1 1
    RB1 UBE3C 0 0 55 158 1 1
    RB1 GOLGB1 0 0 310 309 1 1
    RB1 DCAF10 0 0 0 493 1 1
    RB1 COPS2 0 0 0 183 1 1
    RB1 SNAPC4 0 0 0 223 1 1
    RB1 SPOP 0 0 142 193 1 1
    RB1 KDM4A 270 0 102 354 1 1
    RB1 THAP1 0 0 408 452 1 1
    RB1 SHH 0 0 241 261 1 1
    RB1 SMYD3 0 0 112 232 1 1
    RB1 ATAD2 0 0 103 155 1 1
    RB1 HDLBP 0 0 46 150 1 1
    RB1 USP4 486 0 0 509 1 1
    RB1 CD8A 0 0 212 212 1 1
    RB1 MNAT1 270 0 0 270 1 1
    RB1 RPA2 270 0 48 321 1 1
    RB1 IGFBP3 0 0 193 193 1 1
    RB1 ARID1B 0 720 45 730 1 1
    RB1 FZR1 270 600 124 783 1 1
    RB1 SS18 0 720 61 742 1 1
    RB1 MMP2 0 0 298 298 1 1
    RB1 EHD4 0 0 0 157 1 1
    RB1 TOB1 0 0 42 150 1 1
    RB1 UHRF2 486 0 135 547 1 1
    RB1 TCF7 0 0 48 213 1 1
    RB1 ETV1 0 0 90 184 1 1
    RB1 AURKB 270 0 261 473 1 1
    RB1 ANAPC1 0 600 0 625 1 1
    RB1 SKP2 270 900 713 978 1 1
    RB1 BTG3 0 0 91 194 1 1
    RB1 E4F1 270 0 167 453 1 1
    RB1 ENO2 0 0 134 194 1 1
    RB1 TBX3 0 0 97 414 1 1
    RB1 PAQR5 0 0 233 232 1 1
    RB1 NFIC 0 0 93 166 1 1
    RB1 PXN 0 0 175 175 1 1
    RB1 HIST2H3PS2 0 0 584 590 1 1
    RB1 SDCCAG8 0 0 65 209 1 1
    RB1 KLF5 0 0 141 173 1 1
    RB1 TNS1 0 0 212 242 1 1
    RB1 NR3C1 0 0 387 410 1 1
    RB1 SAMD11 0 0 0 165 1 1
    RB1 SMARCB1 213 720 212 841 1 1
    RB1 H2AFZ 0 900 96 916 1 1
    RB1 CTGF 0 0 164 163 1 1
    RB1 GMEB2 0 0 0 165 1 1
    RB1 FLG 0 0 298 314 1 1
    RB1 RPS6KB2 0 0 0 218 1 2
    RB1 PGRMC1 0 0 363 363 1 1
    RB1 CDKN1C 270 900 395 963 1 1
    RB1 SCMH1 0 0 0 163 1 1
    RB1 HPCAL4 0 0 0 190 1 1
    RB1 SRGAP1 0 0 0 188 1 1
    RB1 MRPL11 0 900 0 900 1 1
    RB1 RAD17 0 0 103 176 1 1
    RB1 MYCL 0 0 260 276 1 1
    RB1 CEBPD 462 0 108 508 1 1
    RB1 NES 0 0 294 294 1 1
    RB1 RPTOR 0 0 134 177 1 2
    RB1 BPTF 0 0 67 266 1 1
    RB1 ABT1 0 0 0 353 1 1
    RB1 RPS6KA3 0 0 157 156 1 1
    RB1 LIN52 0 0 169 461 1 1
    RB1 CHEK2 270 0 394 560 1 1
    RB1 YIPF6 0 0 0 158 1 1
    RB1 PLK2 0 0 96 186 1 1
    RB1 MAPK9 213 0 91 305 1 2
    RB1 MIER1 0 0 66 191 1 1
    RB1 CASP9 270 0 325 497 1 1
    RB1 NANOG 0 0 247 246 1 1
    RB1 ETS1 0 0 170 225 1 1
    RB1 SMARCA5 0 0 112 248 1 1
    RB1 SETD7 270 0 194 510 1 1
    RB1 MLLT10 0 0 0 174 1 1
    RB1 KCNJ13 0 0 45 288 1 1
    RB1 TROVE2 0 0 90 230 1 1
    RB1 PPEF1 0 0 0 163 1 1
    RB1 TUBB3 0 0 270 270 1 1
    RB1 MYLK 0 0 96 186 1 1
    RB1 CASP8 270 0 295 475 1 2
    RB1 MCM4 0 0 102 450 1 1
    RB1 SNAPC3 270 0 0 270 1 1
    RB1 PIWIL4 0 0 81 225 1 1
    RB1 HERC4 259 0 0 303 1 1
    RB1 PHF11 0 0 0 159 1 1
    RB1 KAT2A 0 0 155 188 1 1
    RB1 PGK1 0 0 67 306 1 2
    RB1 ENSG00000269905 0 0 117 583 1 1
    RB1 FNDC3A 0 0 57 251 1 1
    RB1 STK32A 0 0 0 200 1 1
    RB1 LGALS4 0 0 209 209 1 1
    RB1 PPP2R5A 0 0 61 166 1 1
    RB1 NR3C2 0 0 134 166 1 1
    RB1 SCML1 0 0 0 163 1 1
    RB1 SUZ12 0 0 472 530 1 1
    RB1 CCNB3 0 0 0 252 1 1
    RB1 TEAD3 0 0 42 168 1 1
    RB1 CUL5 0 0 150 172 1 1
    RB1 H2AFX 0 900 256 924 1 1
    RB1 CUX1 270 0 242 423 1 1
    RB1 KIF20A 0 0 57 178 1 1
    RB1 IL1A 0 0 160 159 1 1
    RB1 CDK6 880 900 783 997 1 1
    RB1 KMT2B 0 0 156 281 1 1
    RB1 HDAC8 0 0 143 266 1 1
    RB1 NEUROG3 0 0 66 337 1 1
    RB1 GLI2 0 0 155 205 1 1
    RB1 HIST1H4E 0 0 294 304 1 1
    RB1 MORF4L2 270 0 0 307 1 1
    RB1 NXF1 0 0 384 384 1 1
    RB1 ZEB2 0 0 135 173 1 1
    RB1 FRK 270 0 63 299 1 1
    RB1 RERG 0 0 0 162 1 1
    RB1 MOB3B 0 0 166 238 1 1
    RB1 HK2 0 0 117 177 1 1
    RB1 PRH2 0 0 724 724 1 1
    RB1 GNL3 0 0 74 228 1 1
    RB1 LMNA 750 0 713 925 1 1
    RB1 EXO1 0 0 66 150 1 1
    RB1 ZSCAN2 0 0 0 181 1 1
    RB1 DDIT3 0 0 145 237 1 2
    RB1 LPP 0 0 0 150 1 1
    RB1 RNF40 270 0 0 288 1 1
    RB1 IVL 0 0 372 372 1 1
    RB1 ZNF143 0 0 74 164 1 1
    RB1 CKS1B 0 0 132 325 1 1
    RB1 TOR1A 0 0 74 196 1 1
    RB1 HIST1H4I 0 0 294 304 1 1
    RB1 CDK4 992 900 919 999 1 1
    RB1 FADD 0 0 193 193 1 2
    RB1 GNL3L 0 0 0 260 1 1
    RB1 GATA3 0 0 193 241 1 1
    RB1 NF2 0 0 211 229 1 1
    RB1 MTAP 0 0 81 204 1 1
    RB1 TRIM23 0 0 0 166 1 1
    RB1 XRCC6 0 0 140 267 1 1
    RB1 DEAF1 0 0 0 388 1 1
    RB1 EZH2 270 0 462 673 1 1
    RB1 STAT3 270 0 347 502 1 2
    RB1 POU5F1B 0 0 0 178 1 1
    RB1 CDK14 488 0 0 624 1 1
    RB1 AGO2 270 0 210 460 1 1
    RB1 TGFA 0 0 141 164 1 1
    RB1 RBBP6 270 0 323 486 1 1
    RB1 TRERF1 0 0 123 272 1 1
    RB1 SETD8 0 0 81 223 1 1
    RB1 RPGR 0 0 67 313 1 1
    RB1 SRSF1 0 0 144 162 1 1
    RB1 MLH3 0 0 0 261 1 1
    RB1 PPP3CB 0 0 0 163 1 1
    RB1 NXT2 0 0 0 159 1 1
    RB1 MEN1 0 0 194 194 1 1
    RB1 BDP1 213 0 63 251 1 1
    RB1 TRNT1 0 0 46 161 1 1
    RB1 ZBED1 0 0 86 169 1 1
    RB1 NR4A3 0 0 57 396 1 1
    RB1 C3orf62 294 0 0 294 1 1
    RB1 TFAP2B 0 0 0 320 1 1
    RB1 PIK3CA 0 0 414 504 1 2
    RB1 ANAPC15 0 600 0 600 1 1
    RB1 RARG 0 0 0 388 1 1
    RB1 PAX7 0 0 150 298 1 1
    RB1 MYC 671 0 611 866 1 2
    RB1 STK32B 0 0 0 200 1 1
    RB1 GSC 0 900 0 900 1 1
    RB1 UBE2D1 0 600 0 619 1 1
    RB1 H1F0 0 900 291 926 1 1
    RB1 HIST1H2BD 0 900 0 902 1 1
    RB1 RIT1 0 0 60 152 1 1
    RB1 SDHC 0 0 285 334 1 1
    RB1 IGF1R 0 0 292 316 1 1
    RB1 TAB2 0 0 72 168 1 1
    RB1 CTSV 163 0 0 163 1 1
    RB1 UBE2K 0 0 135 176 1 1
    RB1 PLEKHA5 0 0 0 157 1 1
    RB1 CIDEA 0 0 92 189 1 1
    RB1 EML4 0 0 126 201 1 1
    RB1 ENSG00000272772 0 0 0 185 1 1
    RB1 AKT2 0 0 170 184 1 1
    RB1 MECP2 0 0 134 157 1 1
    RB1 POLR2F 0 0 0 175 1 1
    RB1 NFE2L2 0 0 171 172 1 1
    RB1 EHMT2 0 0 142 345 1 1
    RB1 EID1 874 0 684 958 1 1
    RB1 HIST1H2BM 0 900 0 900 1 1
    RB1 PCNT 0 0 367 367 1 1
    RB1 MAP2K1 0 0 294 294 1 1
    RB1 BRD9 0 720 0 735 1 1
    RB1 SCML2 0 0 0 163 1 1
    RB1 TADA2A 0 0 0 222 1 1
    RB1 HDAC5 0 0 0 232 1 1
    RB1 ACRC 0 0 0 254 1 1
    RB1 MYCN 270 0 369 528 1 1
    RB1 PPP3CC 0 0 0 163 1 1
    RB1 SMAD4 0 0 282 299 1 1
    RB1 HDAC3 675 900 160 974 1 1
    RB1 HIST1H4L 0 0 294 304 1 1
    RB1 SFTPA2 0 0 328 328 1 1
    RB1 ANAPC11 0 600 0 625 1 1
    RB1 HIST1H1A 0 900 0 900 1 1
    RB1 MGMT 0 0 308 307 1 1
    RB1 HES1 0 900 90 914 1 1
    RB1 FOXM1 270 900 348 949 1 1
    RB1 WHSC1 0 0 47 286 1 1
    RB1 PLAGL1 0 0 122 177 1 1
    RB1 CCNB1 488 0 518 799 1 1
    RB1 ANXA5 0 0 406 406 1 1
    RB1 PLK1 0 0 358 422 1 1
    RB1 PPP2R2A 0 0 444 456 1 1
    RB1 BCKDHA 0 0 0 302 1 1
    RB1 CTDSPL2 0 0 84 190 1 1
    RB1 POU3F2 0 0 124 254 1 1
    RB1 EP400 0 0 181 262 1 1
    RB1 TWSG1 0 0 151 169 1 1
    RB1 CIDEC 0 0 46 169 1 1
    RB1 STAG2 0 0 92 351 1 1
    RB1 PIN4 0 0 123 159 1 1
    RB1 POLE 0 0 60 282 1 1
    RB1 LMAN2 0 0 0 241 1 1
    RB1 BIRC2 0 0 150 170 1 1
    RB1 IFNG 0 0 124 156 1 2
    RB1 SMAD2 0 0 233 256 1 1
    RB1 ELF1 270 900 0 925 1 1
    RB1 HIST1H2AC 0 900 0 902 1 1
    RB1 NF1 0 0 336 420 1 1
    RB1 SCYL1 0 0 0 207 1 1
    RB1 RAP1A 0 0 97 153 1 1
    RB1 UBE2V2 0 0 0 254 1 1
    RB1 GPS1 0 0 0 307 1 1
    RB1 ATRX 0 0 203 417 1 1
    RB1 SNW1 270 0 66 311 1 1
    RB1 WDR73 0 0 0 493 1 1
    RB1 USP45 0 0 44 173 1 1
    RB1 CABIN1 0 900 45 902 1 1
    RB1 PELP1 270 0 447 579 1 2
    RB1 BCL2L1 0 0 382 433 1 2
    RB1 ANAPC5 0 600 0 649 1 1
    RB1 L3MBTL3 0 0 0 163 1 1
    RB1 ENSG00000255730 0 0 0 302 1 1
    RB1 HMGB2 0 0 94 160 1 1
    RB1 DNMT3B 0 0 260 260 1 1
    RB1 XPA 126 0 99 178 1 1
    RB1 DNMT3A 486 0 264 605 1 1
    RB1 UHRF1 270 0 235 431 1 1
    RB1 CDC73 0 0 103 204 1 1
    RB1 MIER3 0 0 0 170 1 1
    RB1 MCMDC2 0 0 0 227 1 1
    RB1 H2AFV 0 900 46 912 1 1
    RB1 CDK2 913 900 689 997 1 1
    RB1 AFAP1 0 0 605 605 1 1
    RB1 XPO1 0 0 184 201 1 1
    RB1 MSI1 0 0 85 187 1 1
    RB1 MED27 0 0 57 169 1 1
    RB1 ERBB2IP 0 0 0 164 1 1
    RB1 FAT1 0 0 160 167 1 1
    RB1 IL1B 0 0 207 207 1 1
    RB1 SP1 865 900 710 995 1 1
    RB1 SIRT5 0 0 134 170 1 1
    RB1 HIF1A 270 0 334 581 1 2
    RB1 PRKCB 270 0 90 378 1 2
    RB1 CCDC169-SOHLH2 0 0 0 434 1 1
    RB1 RINT1 270 0 0 270 1 1
    RB1 CNTD2 0 0 48 258 1 1
    RB1 NCR1 0 720 0 720 1 1
    RB1 RQCD1 0 0 0 186 1 1
    RB1 LATS2 0 0 180 180 1 1
    RB1 ID1 0 0 181 194 1 1
    RB1 CHM 0 0 0 226 1 1
    RB1 IL6 0 0 310 309 1 1
    RB1 NFYB 0 900 45 901 1 1
    RB1 MYSM1 0 540 0 552 1 1
    RB1 TBX2 0 0 156 714 1 1
    RB1 E2F6 0 0 681 824 1 1
    RB1 KRT12 0 0 75 169 1 1
    RB1 MYOG 0 0 193 248 1 1
    RB1 CCNF 0 0 74 286 1 1
    RB1 RPS6 0 0 142 193 1 1
    RB1 H3F3A 0 0 161 253 1 1
    RB1 CBX3 128 0 137 291 1 1
    RB1 CCNC 270 0 202 643 1 1
    RB1 PTPN13 0 0 107 168 1 1
    RB1 NOTCH1 73 0 400 430 1 1
    RB1 FGF13 0 0 180 179 1 1
    RB1 POTEF 0 0 141 177 1 1
    RB1 SDE2 0 0 0 261 1 1
    RB1 TBR1 0 0 213 304 1 1
    RB1 SMARCAD1 0 0 0 153 1 1
    RB1 ORC4 0 0 71 175 1 1
    RB1 CCNG1 0 0 213 386 1 1
    RB1 KRT7 0 0 143 170 1 1
    RB1 GSK3B 0 0 162 238 1 2
    RB1 PPP6C 0 0 112 241 1 1
    RB1 CDKN2A 0 900 758 975 1 2
    RB1 RPS27A 0 900 0 907 1 1
    RB1 GTF2E1 0 0 54 236 1 1
    RB1 GP5 0 0 181 213 1 1
    RB1 MRPS18B 486 0 67 518 1 1
    RB1 ELSPBP1 0 0 193 193 1 1
    RB1 CEBPB 675 0 382 797 1 1
    RB1 SOX1 0 0 183 183 1 1
    RB1 PIK3CD 0 0 67 164 1 1
    RB1 BANF1 0 0 450 450 1 1
    RB1 WTIP 0 0 0 150 1 1
    RB1 MORF4L1 486 0 424 711 1 1
    RB1 PHC3 0 0 323 323 1 1
    RB1 POC1A 0 0 0 207 1 1
    RB1 HDAC9 0 0 113 263 1 1
    RB1 BRCA2 0 0 320 376 1 1
    RB1 NUF2 0 0 71 218 1 1
    RB1 UBE2V1 0 0 0 254 1 1
    RB1 SMURF1 0 0 58 172 1 1
    RB1 PTGS2 0 0 249 248 1 1
    RB1 ARID3A 0 0 95 197 1 1
    RB1 CASP3 488 900 508 973 1 2
    RB1 ERBB3 0 0 252 268 1 1
    RB1 TONSL 0 0 0 165 1 1
    RB1 GPER1 0 0 174 173 1 1
    RB1 PHF21B 0 0 0 178 1 1
    RB1 SMARCA1 0 0 117 253 1 1
    RB1 HARS 0 0 0 243 1 1
    RB1 HIST1H1E 0 900 0 900 1 1
    RB1 HDAC11 270 0 90 407 1 1
    RB1 CDC20B 0 0 0 254 1 1
    RB1 RAD21 0 0 84 294 1 1
    RB1 HIST1H2BB 0 900 62 902 1 1
    RB1 FMO5 0 0 721 721 1 1
    RB1 SRRM4 0 0 102 183 1 1
    RB1 IL2 0 0 155 154 1 1
    RB1 CAB39L 0 0 52 156 1 1
    RB1 SMARCD3 0 720 43 726 1 1
    RB1 ABCB1 0 0 125 154 1 1
    RB1 THBS1 0 0 184 183 1 1
    RB1 BECN1 0 0 212 212 1 2
    RB1 CDKN2C 0 0 457 471 1 1
    RB1 MLH1 0 0 234 234 1 1
    RB1 CHAF1A 0 0 48 300 1 1
    RB1 NCAPD2 0 0 82 265 1 1
    RB1 NCCRP1 0 0 0 208 1 1
    RB1 DUSP1 0 900 96 909 1 1
    RB1 CDC25A 0 0 395 469 1 1
    RB1 TMPO 270 0 91 395 1 1
    RB1 SCD5 0 0 51 151 1 1
    RB1 KIAA0100 0 0 0 150 1 1
    RB1 MSH4 0 0 0 159 1 1
    RB1 RBBP8 874 0 96 881 1 1
    RB1 PES1 0 0 0 159 1 1
    RB1 MNDA 213 0 0 263 1 1
    RB1 PRKAR1A 0 0 199 229 1 2
    RB1 WDR59 0 0 0 505 1 1
    RB1 GAS7 0 0 0 157 1 1
    RB1 FASLG 0 0 166 165 1 1
    RB1 KDM6B 0 0 210 294 1 1
    RB1 TRDMT1 0 0 74 420 1 1
    RB1 SRP14 0 0 0 188 1 1
    RB1 STAT5A 0 0 180 179 1 1
    RB1 MCM6 0 0 96 272 1 1
    RB1 WDR17 0 0 0 183 1 1
    RB1 KDM2B 0 0 154 178 1 1
    RB1 LIN54 270 0 165 654 1 1
    RB1 ASCL1 0 0 145 203 1 1
    RB1 SOHLH1 0 0 45 209 1 1
    RB1 FOXK1 252 0 0 266 1 1
    RB1 SFMBT1 0 0 0 163 1 1
    RB1 ZNF239 0 0 180 210 1 1
    RB1 SLC35B1 0 0 0 252 1 1
    RB1 ANAPC10 0 600 0 622 1 1
    RB1 PTH 0 0 92 228 1 1
    RB1 KRAS 0 0 393 529 1 1
    RB1 PKN2 0 0 74 171 1 1
    RB1 SETDB2 0 0 47 188 1 1
    RB1 TBP 462 900 428 966 1 1
    RB1 FN1 0 0 279 279 1 1
    RB1 ULK1 0 0 102 206 1 2
    RB1 CDC25B 0 0 193 292 1 1
    RB1 RIPK4 0 0 89 163 1 1
    RB1 SETD2 0 0 183 288 1 1
    RB1 PLK3 0 0 91 181 1 1
    RB1 LPAR6 0 0 500 499 1 1
    RB1 MAPKAPK3 156 0 0 155 1 1
    RB1 PRKCA 0 0 234 282 1 1
    RB1 TTK 0 0 82 488 1 1
    RB1 LOR 0 0 392 392 1 1
    RB1 LDB1 270 0 0 423 1 1
    RB1 UBC 0 900 43 911 1 1
    RB1 SERPINB5 0 0 180 179 1 1
    RB1 TEAD4 0 0 67 190 1 1
    RB1 TFDP3 216 0 233 704 1 1
    RB1 WFDC1 0 0 386 386 1 1
    RB1 TET2 0 0 140 172 1 1
    RB1 MCM2 0 0 218 505 1 1
    RB1 TERT 0 900 459 945 1 1
    RB1 CYB5D2 0 0 73 217 1 1
    RB1 CDC45 0 0 116 154 1 1
    RB1 NKX2-1 0 0 181 197 1 1
    RB1 TTF1 0 0 74 248 1 1
    RB1 MYBL2 0 0 297 470 1 1
    RB1 IRF1 0 0 164 163 1 1
    RB1 ATOH7 0 0 140 200 1 1
    RB1 YAP1 0 650 159 796 1 1
    RB1 SYP 0 0 171 196 1 1
    RB1 TRIP6 0 0 0 150 1 1
    RB1 MYO7A 0 0 151 181 1 1
    RB1 LGR5 0 0 134 225 1 1
    RB1 ELMSAN1 0 0 0 204 1 1
    RB1 NSD1 0 0 63 298 1 1
    RB1 NCL 68 0 152 175 1 1
    RB1 MSH2 0 0 170 302 1 1
    RB1 ESR1 0 0 782 790 1 1
    RB1 POLD1 270 0 70 433 1 1
    RB1 AIRE 0 0 0 178 1 1
    RB1 EOMES 0 0 194 287 1 1
    RB1 TBX6 0 0 0 152 1 1
    RB1 PRL 0 0 184 183 1 1
    RB1 LMNB1 0 0 624 634 1 1
    RB1 CHFR 0 0 103 262 1 1
    RB1 PRIM1 0 650 88 719 1 1
    RB1 E2F3 871 900 987 999 1 1
    RB1 BUB3 0 0 113 205 1 1
    RB1 BAG1 270 0 95 311 1 2
    RB1 HIST1H4K 0 0 294 304 1 1
    RB1 MROH2B 0 0 0 173 1 1
    RB1 RCOR2 0 0 0 416 1 1
    RB1 KAT5 270 0 233 428 1 2
    RB1 CCNA1 487 900 294 969 1 1
    RB1 KIT 0 0 290 290 1 1
    RB1 COMMD3-BMI1 0 0 334 334 1 1
    RB1 RARB 0 0 194 363 1 1
    RB1 H2BFS 0 900 0 901 1 1
    RB1 TERF1 0 0 113 161 1 1
    RB1 E2F5 678 600 681 975 1 1
    RB1 HBP1 486 0 81 518 1 1
    RB1 POU2F3 0 0 0 384 1 1
    RB1 SRP9 0 0 0 206 1 1
    RB1 PTTG1 0 0 193 193 1 1
    RB1 NPM1 675 0 214 733 1 1
    RB1 PA2G4 486 0 57 552 1 1
    RB1 HHEX 0 0 0 155 1 1
    RB1 UBE2S 0 600 134 669 1 1
    RB1 IL10 0 0 134 152 1 1
    RB1 SNAI1 0 0 260 260 1 1
    RB1 DYRK1B 289 0 0 345 1 1
    RB1 FOSL2 0 0 123 195 1 1
    RB1 SMARCC2 0 720 0 728 1 1
    RB1 ENG 0 0 154 153 1 1
    RB1 MDM4 486 0 289 618 1 1
    RB1 SOX10 0 0 140 159 1 1
    RB1 REV3L 0 0 72 156 1 1
    RB1 TEAD1 0 0 72 194 1 1
    RB1 IGF2 0 0 235 235 1 1
    RB1 PON2 0 0 0 448 1 1
    RB1 CD274 0 0 188 188 1 1
    RB1 HDAC7 0 0 112 262 1 1
    RB1 RCC1 0 0 234 253 1 1
    RB1 SMYD1 0 0 0 151 1 1
    RB1 ABCG2 0 0 167 185 1 1
    RB1 ATR 0 0 233 351 1 1
    RB1 BCL2L2 0 0 150 220 1 1
    RB1 NTRK1 63 0 180 213 1 1
    RB1 EGR2 0 0 166 197 1 1
    RB1 UBL4A 279 0 0 360 1 1
    RB1 LOX 0 0 183 183 1 1
    RB1 SGK1 0 0 106 254 1 1
    RB1 IRS1 0 0 195 195 1 1
    RB1 EHD3 0 0 0 157 1 1
    RB1 REM1 0 0 0 239 1 1
    RB1 NACC2 0 0 398 420 1 1
    RB1 RPS6KB1 0 0 320 445 1 2
    RB1 AHR 854 0 134 871 1 1
    RB1 SERPINE1 0 0 164 163 1 1
    RB1 DOT1L 0 0 96 187 1 1
    RB1 NCOR1 0 0 378 610 1 1
    RB1 CDK1 870 900 688 996 1 1
    RB1 HIST1H4B 0 0 294 304 1 1
    RB1 PGR 0 0 688 700 1 1
    RB1 MUC1 0 0 181 227 1 1
    RB1 DEK 0 0 211 228 1 1
    RB1 BARD1 0 0 96 159 1 1
    RB1 CAT 0 0 174 173 1 1
    RB1 TAL1 486 0 57 494 1 1
    RB1 MECOM 0 0 108 160 1 1
    RB1 ATG2A 0 0 0 161 1 2
    RB1 RASA1 129 0 90 194 1 1
    RB1 KIF14 0 0 155 189 1 1
    RB1 MCM7 835 0 486 946 1 1
    RB1 POU5F1 0 0 264 369 1 1
    RB1 HGF 0 0 218 391 1 1
    RB1 SMYD5 0 0 0 151 1 1
    RB1 LRP2BP 0 0 170 312 1 1
    RB1 HPRT1 0 0 135 153 1 1
    RB1 TMEM189-UBE2V1 0 0 0 254 1 1
    RB1 TMEM178A 0 0 0 206 1 1
    RB1 FOXA2 0 0 164 240 1 1
    RB1 BCL2 0 0 187 254 1 2
    RB1 MYB 0 0 134 347 1 1
    RB1 BAK1 0 0 103 177 1 2
    RB1 LIN28A 0 0 138 157 1 1
    RB1 PRB3 0 0 737 737 1 1
    RB1 ZCCHC7 0 0 448 448 1 1
    RB1 CTLA4 0 0 156 155 1 1
    RB1 TFAP2C 0 0 94 357 1 1
    RB1 RBFOX3 0 0 155 162 1 1
    RB1 NXNL1 0 0 0 191 1 1
    RB1 CDK3 0 0 261 458 1 1
    RB1 ITCH 0 0 306 390 1 1
    RB1 PAX3 0 0 171 364 1 1
    RB1 RBBP7 835 0 270 933 1 1
    RB1 LEO1 0 0 54 150 1 1
    RB1 SIN3A 0 0 155 320 1 1
    RB1 MEF2C 0 900 134 914 1 1
    RB1 KRT14 0 0 450 450 1 1
    RB1 GPR125 0 0 0 237 1 1
    RB1 ASCC1 0 0 0 157 1 1
    RB1 VDR 270 0 123 357 1 1
    RB1 NR4A2 0 0 57 230 1 1
    RB1 TRAP1 462 0 0 461 1 2
    RB1 STK32C 0 0 0 200 1 1
    RB1 RNF4 270 0 103 337 1 1
    RB1 TNF 0 0 261 266 1 1
    RB1 NFYC 0 900 55 918 1 1
    RB1 DCLRE1A 0 0 0 227 1 1
    RB1 FHIT 0 0 218 218 1 1
    RB1 NCAPH2 0 600 0 682 1 1
    RB1 EZH1 0 0 122 298 1 1
    RB1 SYF2 0 0 53 182 1 1
    RB1 DP2 676 800 117 970 1 1
    RB1 ENSG00000142539 0 0 0 232 1 1
    RB1 HPR 0 0 267 267 1 1
    RB1 PGK2 0 0 0 449 1 1
    RB1 HIST1H2AJ 0 900 0 902 1 1
    RB1 DRAM1 0 0 113 168 1 2
    RB1 CD9 0 0 330 330 1 1
    RB1 SMC5 0 0 43 487 1 1
    RB1 HECW1 0 0 0 169 1 1
    RB1 PROX1 0 0 165 170 1 1
    RB1 CSNK2A1 0 0 270 273 1 1
    RB1 IFI16 270 0 54 326 1 1
    RB1 CCND2 768 900 504 992 1 1
    RB1 TFAP2A 270 0 70 657 1 1
    RB1 CDK13 218 0 49 352 1 1
    RB1 CDC7 0 0 113 156 1 1
    RB1 TMPRSS2 0 0 101 194 1 1
    RB1 IRF3 157 0 116 222 1 1
    RB1 ERBB2 0 0 460 471 1 2
    RB1 HMGA2 297 900 822 990 1 1
    RB1 FANCD2 0 0 134 192 1 1
    RB1 MTL5 0 0 0 479 1 1
    RB1 MAP3K1 0 0 142 213 1 1
    RB1 CCNE2 0 800 391 908 1 1
    RB1 ANAPC4 0 600 0 622 1 1
    RB1 CDK15 0 0 49 303 1 1
    RB1 KIAA1456 0 0 155 177 1 1
    RB1 SMC4 0 600 66 778 1 1
    RB1 WDHD1 0 0 0 183 1 1
    RB1 TSC22D2 0 0 57 171 1 1
    RB1 RNF7 0 0 45 183 1 1
    RB1 CDC16 270 600 0 715 1 1
    RB1 CCNG2 0 0 124 317 1 1
    RB1 ID2 486 900 333 963 1 1
    RB1 EMD 0 0 178 177 1 1
    RB1 SIRT4 0 0 141 249 1 1
    RB1 BIRC5 0 0 243 306 1 2
    RB1 MCM9 0 0 0 393 1 1
    RB1 ATOH1 0 0 148 206 1 1
    RB1 RAI1 0 0 0 159 1 1
    RB1 STAG3 0 0 0 315 1 1
    RB1 RUNX2 270 900 899 992 1 1
    RB1 PPP2R4 0 0 325 325 1 1
    RB1 DLG1 0 0 150 167 1 1
    RB1 CEBPG 0 0 0 175 1 1
    RB1 XIAP 0 0 243 252 1 1
    RB1 FGFR1 0 0 260 265 1 1
    RB1 KLF4 0 0 175 205 1 1
    RB1 IKBKB 0 0 134 190 1 1
    RB1 FOXA1 0 0 166 254 1 1
    RB1 KNTC1 0 0 0 213 1 1
    RB1 SGK3 0 0 70 255 1 1
    RB1 PRDM16 0 0 170 224 1 1
    RB1 HOXA10 0 0 170 169 1 1
    RB1 RRM1 0 0 203 326 1 1
    RB1 HIST1H2BA 0 900 0 900 1 1
    RB1 CD4 0 0 213 213 1 1
    RB1 PPARG 270 900 285 945 1 1
    RB1 SLIT2 0 0 124 157 1 1
    RB1 UBE3A 0 0 393 429 1 1
    RB1 PPP1R13L 0 0 56 154 1 1
    RB1 SETX 0 0 0 163 1 1
    RB1 TGFB2 0 0 154 206 1 1
    RB1 AKT1 0 900 565 955 1 2
    RB1 GBP2 0 0 331 331 1 1
    RB1 MKI67 0 0 181 311 1 1
    RB1 UBR4 270 0 448 580 1 1
    RB1 TEAD2 0 0 64 187 1 1
    RB1 HSD17B2 0 0 163 163 1 1
    RB1 TRIP11 270 0 57 282 1 1
    RB1 CDKN1B 0 900 566 965 1 2
    RB1 CD2 0 0 438 438 1 1
    RB1 CTCF 0 0 161 192 1 1
    RB1 GTF2B 0 0 108 265 1 1
    RB1 MSX2 0 0 91 182 1 1
    RB1 TSC2 0 0 210 280 1 2
    RB1 TRRAP 0 0 96 313 1 1
    RB1 RBX1 0 0 125 251 1 1
    RB1 HACE1 0 0 0 201 1 1
    RB1 PIAS4 0 0 112 169 1 1
    RB1 NFATC2 129 0 90 225 1 1
    RB1 JAK1 0 0 108 156 1 1
    RB1 MITF 0 0 210 211 1 1
    RB1 RASSF1 0 0 335 335 1 1
    RB1 KDM5A 753 0 750 939 1 1
    RB1 HMOX1 0 0 134 157 1 2
    RB1 RBPJL 0 0 73 419 1 1
    RB1 TCHP 0 0 720 720 1 1
    RB1 TBX4 0 0 0 152 1 1
    RB1 TEN1-CDK3 488 0 261 710 1 1
    RB1 WWP2 0 0 46 162 1 1
    RB1 ZBTB24 0 0 0 165 1 1
    RB1 EIF2AK3 0 0 402 402 1 2
    RB1 TCF12 0 0 61 165 1 1
    RB1 NTMT1 270 0 134 340 1 1
    RB1 UBE2C 0 600 74 627 1 1
    RB1 CIB1 0 0 280 404 1 1
    RB1 CKAP2 0 0 82 155 1 1
    RB1 ACTL6A 0 720 89 746 1 1
    RB1 EED 0 0 439 687 1 1
    RB1 SRC 0 0 766 770 1 1
    RB1 SMARCC1 0 720 57 733 1 1
    RB1 MCM3 0 0 182 613 1 1
    RB1 CCNI2 0 0 0 252 1 1
    RB1 G2E3 0 0 0 159 1 1
    RB1 ATAD5 0 0 0 219 1 1
    RB1 SMURF2 0 0 74 186 1 1
    RB1 KDM6A 0 0 252 331 1 1
    RB1 PCSK9 0 0 112 154 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
    GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IBA
    GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables IEA
    GO:0097718 Molecular Function disordered domain specific binding enables IPI
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0061676 Molecular Function importin-alpha family protein binding enables IPI
    GO:0019900 Molecular Function kinase binding enables IDA
    GO:0060090 Molecular Function molecular adaptor activity enables EXP
    GO:0051219 Molecular Function phosphoprotein binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0003714 Molecular Function transcription corepressor activity enables TAS
    GO:0031625 Molecular Function ubiquitin protein ligase binding enables IPI
    GO:0000082 Biological Process G1/S transition of mitotic cell cycle involved_in IEA
    GO:0007265 Biological Process Ras protein signal transduction involved_in IEP
    GO:0003180 Biological Process aortic valve morphogenesis involved_in ISS
    GO:0030154 Biological Process cell differentiation involved_in IBA
    GO:0051301 Biological Process cell division involved_in IEA
    GO:0048667 Biological Process cell morphogenesis involved in neuron differentiation involved_in IBA
    GO:0032869 Biological Process cellular response to insulin stimulus involved_in IEA
    GO:0071466 Biological Process cellular response to xenobiotic stimulus involved_in IEA
    GO:0002062 Biological Process chondrocyte differentiation involved_in IEA
    GO:0006338 Biological Process chromatin remodeling involved_in TAS
    GO:0051276 Biological Process chromosome organization involved_in IMP
    GO:0048565 Biological Process digestive tract development involved_in IEA
    GO:0043353 Biological Process enucleate erythrocyte differentiation involved_in IEA
    GO:0050673 Biological Process epithelial cell proliferation involved_in IEA
    GO:0034349 Biological Process glial cell apoptotic process involved_in IEA
    GO:0014009 Biological Process glial cell proliferation involved_in IEA
    GO:0097284 Biological Process hepatocyte apoptotic process involved_in IEA
    GO:0031507 Biological Process heterochromatin formation involved_in IDA
    GO:0034088 Biological Process maintenance of mitotic sister chromatid cohesion involved_in IMP
    GO:0045445 Biological Process myoblast differentiation involved_in IMP
    GO:0043433 Biological Process negative regulation of DNA-binding transcription factor activity involved_in TAS
    GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
    GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IMP
    GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in TAS
    GO:2000134 Biological Process negative regulation of G1/S transition of mitotic cell cycle involved_in IBA
    GO:2000134 Biological Process negative regulation of G1/S transition of mitotic cell cycle acts_upstream_of TAS
    GO:2001234 Biological Process negative regulation of apoptotic signaling pathway involved_in ISS
    GO:0045786 Biological Process negative regulation of cell cycle involved_in ISS
    GO:0030308 Biological Process negative regulation of cell growth involved_in ISS
    GO:0120163 Biological Process negative regulation of cold-induced thermogenesis involved_in ISS
    GO:0050680 Biological Process negative regulation of epithelial cell proliferation involved_in IEA
    GO:0010629 Biological Process negative regulation of gene expression acts_upstream_of_or_within IMP
    GO:0060253 Biological Process negative regulation of glial cell proliferation involved_in IEA
    GO:1903944 Biological Process negative regulation of hepatocyte apoptotic process involved_in IEA
    GO:0050728 Biological Process negative regulation of inflammatory response involved_in ISS
    GO:1904761 Biological Process negative regulation of myofibroblast differentiation involved_in ISS
    GO:0006469 Biological Process negative regulation of protein kinase activity involved_in IPI
    GO:0045879 Biological Process negative regulation of smoothened signaling pathway involved_in IEA
    GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in TAS
    GO:0051402 Biological Process neuron apoptotic process involved_in IEA
    GO:0042551 Biological Process neuron maturation involved_in IEA
    GO:0031175 Biological Process neuron projection development involved_in IBA
    GO:1904028 Biological Process positive regulation of collagen fibril organization involved_in ISS
    GO:1903055 Biological Process positive regulation of extracellular matrix organization involved_in ISS
    GO:0045651 Biological Process positive regulation of macrophage differentiation involved_in IEA
    GO:0045842 Biological Process positive regulation of mitotic metaphase/anaphase transition involved_in IMP
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IEA
    GO:2000679 Biological Process positive regulation of transcription regulatory region DNA binding acts_upstream_of_or_within IDA
    GO:0071459 Biological Process protein localization to chromosome, centromeric region involved_in IMP
    GO:0006355 Biological Process regulation of DNA-templated transcription involved_in IDA
    GO:0006355 Biological Process regulation of DNA-templated transcription involved_in ISS
    GO:0006355 Biological Process regulation of DNA-templated transcription involved_in NAS
    GO:0051726 Biological Process regulation of cell cycle involved_in TAS
    GO:0090230 Biological Process regulation of centromere complex assembly involved_in TAS
    GO:0043550 Biological Process regulation of lipid kinase activity involved_in IDA
    GO:0007346 Biological Process regulation of mitotic cell cycle involved_in IMP
    GO:0031134 Biological Process sister chromatid biorientation involved_in IMP
    GO:0035914 Biological Process skeletal muscle cell differentiation involved_in IEA
    GO:0007224 Biological Process smoothened signaling pathway involved_in IEA
    GO:0007283 Biological Process spermatogenesis involved_in IEA
    GO:0051146 Biological Process striated muscle cell differentiation involved_in IEA
    GO:0001894 Biological Process tissue homeostasis involved_in IEA
    GO:0006366 Biological Process transcription by RNA polymerase II involved_in IEA
    GO:0016605 Cellular Component PML body located_in IDA
    GO:0035189 Cellular Component Rb-E2F complex part_of IBA
    GO:0035189 Cellular Component Rb-E2F complex part_of IDA
    GO:0035189 Cellular Component Rb-E2F complex part_of IPI
    GO:0035189 Cellular Component Rb-E2F complex part_of ISS
    GO:0035189 Cellular Component Rb-E2F complex part_of TAS
    GO:0016514 Cellular Component SWI/SNF complex part_of TAS
    GO:0000785 Cellular Component chromatin is_active_in IBA
    GO:0061793 Cellular Component chromatin lock complex part_of IPI
    GO:0008024 Cellular Component cyclin/CDK positive transcription elongation factor complex part_of IDA
    GO:0005737 Cellular Component cytoplasm located_in ISS
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0005634 Cellular Component nucleus located_in NAS
    GO:0005634 Cellular Component nucleus located_in TAS
    GO:0005819 Cellular Component spindle located_in IEA
    Pathways
    Name DB ID
    Inhibition of replication initiation of damaged DNA by RB1/E2F1 Reactome R-HSA-113501
    E2F mediated regulation of DNA replication Reactome R-HSA-113510
    Cell Cycle Reactome R-HSA-1640170
    Disease Reactome R-HSA-1643685
    APC/C-mediated degradation of cell cycle proteins Reactome R-HSA-174143
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Reactome R-HSA-174178
    Generic Transcription Pathway Reactome R-HSA-212436
    Cellular responses to stress Reactome R-HSA-2262752
    Condensation of Prophase Chromosomes Reactome R-HSA-2299718
    Cellular Senescence Reactome R-HSA-2559583
    Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome R-HSA-2559584
    Oncogene Induced Senescence Reactome R-HSA-2559585
    DNA Damage/Telomere Stress Induced Senescence Reactome R-HSA-2559586
    Regulation of mitotic cell cycle Reactome R-HSA-453276
    Mitotic G1 phase and G1/S transition Reactome R-HSA-453279
    Infectious disease Reactome R-HSA-5663205
    Mitotic Prophase Reactome R-HSA-68875
    M Phase Reactome R-HSA-68886
    Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Reactome R-HSA-69200
    Cyclin E associated events during G1/S transition Reactome R-HSA-69202
    G1/S Transition Reactome R-HSA-69206
    Cyclin D associated events in G1 Reactome R-HSA-69231
    G1 Phase Reactome R-HSA-69236
    S Phase Reactome R-HSA-69242
    Cell Cycle, Mitotic Reactome R-HSA-69278
    Cyclin A:Cdk2-associated events at S phase entry Reactome R-HSA-69656
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Gene expression (Transcription) Reactome R-HSA-74160
    Transcriptional regulation by RUNX2 Reactome R-HSA-8878166
    RUNX2 regulates osteoblast differentiation Reactome R-HSA-8940973
    RUNX2 regulates bone development Reactome R-HSA-8941326
    Cellular responses to stimuli Reactome R-HSA-8953897
    Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects Reactome R-HSA-9659787
    Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Reactome R-HSA-9661069
    Defective translocation of RB1 mutants to the nucleus Reactome R-HSA-9661070
    Diseases of mitotic cell cycle Reactome R-HSA-9675126
    SARS-CoV-1 Infection Reactome R-HSA-9678108
    SARS-CoV Infections Reactome R-HSA-9679506
    SARS-CoV-1 Genome Replication and Transcription Reactome R-HSA-9679514
    Replication of the SARS-CoV-1 genome Reactome R-HSA-9682706
    Aberrant regulation of mitotic exit in cancer due to RB1 defects Reactome R-HSA-9687136
    Aberrant regulation of mitotic cell cycle due to RB1 defects Reactome R-HSA-9687139
    SARS-CoV-2 Infection Reactome R-HSA-9694516
    SARS-CoV-2 Genome Replication and Transcription Reactome R-HSA-9694682
    Replication of the SARS-CoV-2 genome Reactome R-HSA-9694686
    Early SARS-CoV-2 Infection Events Reactome R-HSA-9772572
    Viral Infection Pathways Reactome R-HSA-9824446
    Sphingolipid metabolism in senescence (WP5121) WikiPathways WP5121_r119472
    7q11.23 copy number variation syndrome (WP4932) WikiPathways WP4932_r118797
    Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
    Tumor suppressor activity of SMARCB1 (WP4204) WikiPathways WP4204_r123410
    Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
    Thyroid stimulating hormone (TSH) signaling pathway (WP2032) WikiPathways WP2032_r122774
    Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome (WP4320) WikiPathways WP4320_r123412
    Bladder cancer (WP2828) WikiPathways WP2828_r119245
    Melanoma (WP4685) WikiPathways WP4685_r123437
    NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence (WP5046) WikiPathways WP5046_r118987
    Glioblastoma signaling pathways (WP2261) WikiPathways WP2261_r123065
    Cell cycle (WP179) WikiPathways WP179_r122978
    Adipogenesis (WP236) WikiPathways WP236_r105873
    Prostaglandin and leukotriene metabolism in senescence (WP5122) WikiPathways WP5122_r119484
    Aryl hydrocarbon receptor pathway (WP2586) WikiPathways WP2586_r121728
    Prader-Willi and Angelman syndrome (WP3998) WikiPathways WP3998_r123316
    Retinoblastoma gene in cancer (WP2446) WikiPathways WP2446_r116593
    Androgen receptor signaling pathway (WP138) WikiPathways WP138_r122133
    Fas ligand pathway and stress induction of heat shock proteins (WP314) WikiPathways WP314_r121827
    Glycolysis in senescence (WP5049) WikiPathways WP5049_r120508
    Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879) WikiPathways WP4879_r123415
    Ciliary landscape (WP4352) WikiPathways WP4352_r102218
    Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
    Spinal cord injury (WP2431) WikiPathways WP2431_r120812
    DNA damage response (WP707) WikiPathways WP707_r124174
    ID signaling pathway (WP53) WikiPathways WP53_r120698
    G1 to S cell cycle control (WP45) WikiPathways WP45_r123406
    Pancreatic adenocarcinoma pathway (WP4263) WikiPathways WP4263_r123405
    Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
    H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity (WP3969) WikiPathways WP3969_r123402
    Photodynamic therapy-induced AP-1 survival signaling (WP3611) WikiPathways WP3611_r120501
    Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
    miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001407165 1 mRNA transcript variant 2 NC_000013 Reference
    NM_000321 3 mRNA transcript variant 1 NC_000013 Reference
    NM_001407166 1 mRNA transcript variant 3 NC_000013 Reference
    NM_001407167 1 mRNA transcript variant 4 NC_000013 Reference
    NM_001407168 1 mRNA transcript variant 5 NC_000013 Reference