PRKCB

protein kinase C beta
General Information
Name protein kinase C beta
Alias
  • protein kinase C beta type
  • PKC-B
  • protein kinase C, beta 1 polypeptide
Synonyms PKCβ PKC-beta PKCB PKCI(2) PKCbeta PRKCB1 PRKCB2
Gene_family AGC family kinases|C2 domain containing protein kinases|MicroRNA protein coding host genes
organism Homo sapiens
entrez_id 5579
location 16p12.2-p12.1
transcript_count 3
exon_count 18
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
      Stringdb Protein kinase C beta type; Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-64 [...]
      nextProt Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at 'Ser-180', which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity (PubMed:11598012). Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates 'Ser-36' of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer. Acts as a coactivator of androgen receptor (AR)-dependent transcription, by being recruited to AR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 'Lys-4' (H3K4me) by LSD1/KDM1A (PubMed:20228790). In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade. Participates in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4. Phosphorylates SLC2A1/GLUT1, promoting glucose uptake by SLC2A1/GLUT1 (PubMed:25982116). Under high glucose in pancreatic beta-cells, is probably involved in the inhibition of the insulin gene transcription, via regulation of MYC expression. In endothelial cells, activation of PRKCB induces increased phosphorylation of RB1, increased VEGFA-induced cell proliferation, and inhibits PI3K/AKT-dependent nitric oxide synthase (NOS3/eNOS) regulation by insulin, which causes endothelial dysfunction. Also involved in triglyceride homeostasis (By similarity). Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription (PubMed:19176525).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    PRKCB BioGRID ACSL4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID MAPT GeneID BioGRID Biochemical Activity; Proximity Label-MS
    PRKCB BioGRID RICTOR GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID PDK1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID CLTC GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID ACTA1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID PRKCE GeneID BioGRID Negative Genetic
    PRKCB BioGRID PRKCA GeneID BioGRID Affinity Capture-MS; Negative Genetic
    PRKCB BioGRID YWHAE GeneID BioGRID Co-localization
    PRKCB BioGRID PDPK1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
    PRKCB BioGRID MDM2 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID GNB1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID COQ8B GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SHCBP1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PRKCG GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PRKCD GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MTCL3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RDH14 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DELEC1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MBD4 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ZMYND8 GeneID BioGRID Reconstituted Complex
    PRKCB BioGRID IMPDH2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HSPB1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HMGB2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC5 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AZ1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AX GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC7 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC8 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H1-4 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H1-2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ETF1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID FBL GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DHCR7 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SLC25A10 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID COX6C GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CNP GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID AP3S1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CHEK1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ARL2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ARCN1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID AKT1 GeneID BioGRID Affinity Capture-MS; Biochemical Activity; Two-hybrid
    PRKCB BioGRID H2AC19 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID LOC102724334 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID EML3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TAMM41 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H3C14 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H4C16 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID OSBPL8 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RHPN1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AZ2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC25 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC12 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC12 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HSDL2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MAGT1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DERL1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TSEN34 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DDX50 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MRPS5 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MRPS6 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CCAR2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DOLPP1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DHX33 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AJ GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CCAR1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CARMIL1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SRBD1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HPF1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PELO GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ACSL5 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CPSF3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ZC3HC1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID UBXN1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TVP23B GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID UHRF1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID APOBEC3C GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID STK39 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ZNF638 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID GEMIN5 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MTO1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID LEMD3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ICMT GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DDX42 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CDC37 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SEC24A GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TIMM44 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID NDRG1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HUWE1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID ABCF2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID HNRNPDL GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DDX46 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID AKAP12 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TECR GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID GDF15 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TRIP13 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PDLIM7 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID NOLC1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DDX21 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RPS6KA4 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC11 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID EIF2S2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DDX18 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC21 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC14 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC15 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2BC13 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC20 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC6 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC14 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID H2AC13 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID MLF2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID UBC GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID UBB GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID UBA52 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TUBA4A GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID TBCD GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID STAT1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SLC16A1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SLC2A1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SH3GL3 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID SRSF2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RPL27A GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RPL15 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PURB GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID PRKCB GeneID BioGRID Affinity Capture-MS; Biochemical Activity
    PRKCB BioGRID PRKAR1A GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID POLD1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID LBR GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID LIG1 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID NR2C2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DPF2 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID RNF123 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID DRD3 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID DRD2 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID ARRB2 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID GRK2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    PRKCB BioGRID FBXO7 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID BLVRA GeneID BioGRID Biochemical Activity; Reconstituted Complex
    PRKCB BioGRID ITGB3 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID IKBKB GeneID BioGRID Co-localization
    PRKCB BioGRID GSK3B GeneID BioGRID Co-localization
    PRKCB BioGRID CHUK GeneID BioGRID Co-localization
    PRKCB BioGRID DAB2 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID EP300 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID RACK1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    PRKCB BioGRID MBP GeneID BioGRID Biochemical Activity
    PRKCB BioGRID NUMB GeneID BioGRID Biochemical Activity
    PRKCB BioGRID MARCKS GeneID BioGRID Biochemical Activity
    PRKCB BioGRID LYN GeneID BioGRID Affinity Capture-Luminescence
    PRKCB BioGRID H1-5 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID SYT6 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID RB1 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID TNFRSF1A GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID PTPA GeneID BioGRID Biochemical Activity
    PRKCB BioGRID PPP1CA GeneID BioGRID Biochemical Activity
    PRKCB BioGRID ITGB2 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Luminescence
    PRKCB BioGRID GSK3A GeneID BioGRID Biochemical Activity
    PRKCB BioGRID FN1 GeneID BioGRID Affinity Capture-MS
    PRKCB BioGRID CASR GeneID BioGRID Biochemical Activity
    PRKCB BioGRID Marcks GeneID BioGRID Biochemical Activity
    PRKCB BioGRID RASGRP3 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID SDC2 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID CARD11 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    PRKCB BioGRID LMNB1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID H1-0 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID LSP1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID H1-1 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID NCF1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID RBCK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID TOP2A GeneID BioGRID Biochemical Activity
    PRKCB BioGRID IBTK GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID KCNA5 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID RNF31 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID TERF1 GeneID BioGRID Two-hybrid
    PRKCB BioGRID TINF2 GeneID BioGRID Two-hybrid
    PRKCB BioGRID EGFR GeneID BioGRID Biochemical Activity
    PRKCB BioGRID TRIM41 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    PRKCB BioGRID RIGI GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID H3C1 GeneID BioGRID Biochemical Activity
    PRKCB Protein OCLN GeneID HPRD
    PRKCB BioGRID IKBKG GeneID BioGRID Reconstituted Complex
    PRKCB BioGRID HSPA4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    PRKCB Protein GRIN1 GeneID HPRD None
    PRKCB Protein RASGRP3 GeneID HPRD None
    PRKCB Protein HABP4 GeneID HPRD None
    PRKCB Protein PDLIM7 GeneID HPRD None
    PRKCB Protein RIPK4 GeneID HPRD None
    PRKCB Protein ZMYND8 GeneID HPRD None
    PRKCB Protein AFAP1 GeneID HPRD None
    PRKCB Protein SYT6 GeneID HPRD None
    PRKCB Protein MKI67 GeneID HPRD None
    PRKCB Protein MARCKS GeneID HPRD None
    PRKCB Protein CHAT GeneID HPRD None
    PRKCB Protein PEBP1 GeneID HPRD None
    PRKCB Protein CARD11 GeneID HPRD None
    PRKCB Protein GSK3A GeneID HPRD None
    PRKCB Protein PDLIM5 GeneID HPRD None
    PRKCB Protein YWHAG GeneID HPRD None
    PRKCB Protein PDPK1 GeneID HPRD None
    PRKCB Protein GSK3B GeneID HPRD None
    PRKCB Protein GNA13 GeneID HPRD None
    PRKCB Protein GRM5 GeneID HPRD None
    PRKCB Protein NUMB GeneID HPRD None
    PRKCB Protein IKBKB GeneID HPRD None
    PRKCB Protein STXBP1 GeneID HPRD None
    PRKCB Protein EIF6 GeneID HPRD None
    PRKCB Protein MAPK6 GeneID HPRD None
    PRKCB Protein GRIN2D GeneID HPRD None
    PRKCB Protein CYTH2 GeneID HPRD None
    PRKCB Protein CISH GeneID HPRD None
    PRKCB Protein IFNAR2 GeneID HPRD None
    PRKCB Protein NRGN GeneID HPRD None
    PRKCB Protein DVL2 GeneID HPRD None
    PRKCB Protein PA2G4 GeneID HPRD None
    PRKCB Protein DAB2 GeneID HPRD None
    PRKCB Protein CASR GeneID HPRD None
    PRKCB Protein RGS2 GeneID HPRD None
    PRKCB Protein BMPR2 GeneID HPRD None
    PRKCB Protein CHUK GeneID HPRD None
    PRKCB Protein GCNT1 GeneID HPRD None
    PRKCB Protein GABRB2 GeneID HPRD None
    PRKCB Protein ITGB2 GeneID HPRD None
    PRKCB Protein BTK GeneID HPRD None
    PRKCB Protein NCF1 GeneID HPRD None
    PRKCB Protein VTN GeneID HPRD None
    PRKCB Protein ANXA7 GeneID HPRD None
    PRKCB Protein SPTAN1 GeneID HPRD None
    PRKCB Protein RB1 GeneID HPRD None
    PRKCB Protein RRAD GeneID HPRD None
    PRKCB Protein RACK1 GeneID HPRD None
    PRKCB Protein PRKCB GeneID HPRD None
    PRKCB Protein PPP2CB GeneID HPRD None
    PRKCB Protein PTPN11 GeneID HPRD None
    PRKCB Protein KIT GeneID HPRD None
    PRKCB Protein GAP43 GeneID HPRD None
    PRKCB Protein CD5 GeneID HPRD None
    PRKCB Protein ANXA2 GeneID HPRD None
    PRKCB Protein LMNB1 GeneID HPRD None
    PRKCB Protein ITGB7 GeneID HPRD None
    PRKCB Protein SDC2 GeneID HPRD None
    PRKCB Protein CSF2RB GeneID HPRD None
    PRKCB Protein GRIN2B GeneID HPRD None
    PRKCB Protein GABRG2 GeneID HPRD None
    PRKCB Protein EIF4E GeneID HPRD None
    PRKCB Protein EPB41 GeneID HPRD None
    PRKCB Protein TOP2A GeneID HPRD None
    PRKCB Protein GJA1 GeneID HPRD None
    PRKCB Protein GRK2 GeneID HPRD None
    PRKCB Protein LST1 GeneID HPRD None
    PRKCB BioGRID PRL1 GeneID BioGRID Reconstituted Complex
    PRKCB BioGRID AFAP1 GeneID BioGRID Reconstituted Complex
    PRKCB BioGRID PDLIM5 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PRKCB BioGRID TIAM1 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID CDK1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID YWHAG GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID RGS2 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID GNA12 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID RIPK4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKCB BioGRID GNA13 GeneID BioGRID Biochemical Activity
    PRKCB BioGRID CSF2RB GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID NCAM1 GeneID BioGRID Affinity Capture-Western
    PRKCB BioGRID BTK GeneID BioGRID Reconstituted Complex
    PRKCB None None None BIND An unspecified isoform of PKC-beta interacts with Stat3.
    PRKCB Protein NP_056191.1 Protein BIND PKC-beta2 phosphorylates RasGRP3. This interaction was modelled on a demonstrated interaction between human RasGRP3 and PKC-beta2 from an unspecified species.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    PRKCB ITK 0 0 305 213 1 1
    PRKCB MEF2C 0 0 138 217 1 1
    PRKCB VDR 0 0 134 155 1 1
    PRKCB PIK3R2 0 0 170 291 1 1
    PRKCB LPIN2 0 650 0 674 1 1
    PRKCB ADCY6 0 600 60 611 1 1
    PRKCB PTGFR 0 0 0 212 1 1
    PRKCB TNF 0 0 370 382 1 1
    PRKCB PLCB1 0 600 358 774 1 1
    PRKCB GABRG2 213 0 175 363 1 1
    PRKCB MYO18B 0 0 0 165 1 1
    PRKCB FMR1 68 0 46 151 1 1
    PRKCB PDGFC 0 0 143 161 1 1
    PRKCB ADCY7 0 600 166 667 1 1
    PRKCB PEBP1 213 0 54 306 1 1
    PRKCB TXNIP 0 0 148 209 1 1
    PRKCB IL5 0 0 456 456 1 1
    PRKCB RPS6KA2 0 0 95 195 1 1
    PRKCB MAP4K1 0 0 213 186 1 1
    PRKCB CCND2 0 0 181 210 1 1
    PRKCB AP2A2 0 900 81 920 1 1
    PRKCB NFKB2 0 0 233 306 1 1
    PRKCB GCG 0 0 204 204 1 1
    PRKCB TNFAIP3 0 0 287 286 1 1
    PRKCB EMP3 0 0 63 163 1 1
    PRKCB SPN 0 0 170 211 1 1
    PRKCB PIK3C2G 0 0 0 160 1 1
    PRKCB PDZD7 0 0 0 184 1 1
    PRKCB MINK1 0 0 82 227 1 1
    PRKCB GRIA3 0 900 73 917 1 1
    PRKCB ARHGAP9 0 0 74 168 1 1
    PRKCB EVI2A 0 0 0 151 1 1
    PRKCB PFKFB4 0 0 0 542 1 1
    PRKCB CNR1 0 0 70 155 1 1
    PRKCB RETN 0 0 134 159 1 1
    PRKCB UBASH3B 0 0 0 343 1 1
    PRKCB GLRA1 0 0 56 198 1 1
    PRKCB IRS1 0 800 338 861 1 1
    PRKCB HSPA9 0 0 185 185 1 1
    PRKCB UBL4A 0 0 0 155 1 1
    PRKCB RPS6KB1 0 900 259 904 1 2
    PRKCB REM1 0 0 0 156 1 1
    PRKCB AGTR1 0 0 184 196 1 1
    PRKCB ADRB2 0 0 75 158 1 1
    PRKCB CDK1 270 0 233 324 1 1
    PRKCB SERPINE1 0 0 268 268 1 1
    PRKCB CACNA1B 0 0 459 485 1 1
    PRKCB CSF2RB 270 0 329 534 1 1
    PRKCB MYO18A 0 0 0 165 1 1
    PRKCB AKAP5 0 0 61 810 1 1
    PRKCB PDLIM7 270 0 66 322 1 1
    PRKCB SPTBN5 0 360 0 370 1 1
    PRKCB DPYSL5 0 0 0 187 1 1
    PRKCB C17orf97 293 0 0 293 1 1
    PRKCB DVL2 213 900 0 928 1 1
    PRKCB STIM1 0 0 184 183 1 2
    PRKCB KCNJ4 0 0 43 287 1 1
    PRKCB PITPNA 0 0 0 214 1 1
    PRKCB TMEM189-UBE2V1 0 0 0 179 1 1
    PRKCB MLC1 0 0 0 173 1 1
    PRKCB CTLA4 0 0 234 266 1 1
    PRKCB RRAS2 0 600 193 671 1 1
    PRKCB PLEKHG3 0 0 92 154 1 1
    PRKCB ARHGEF25 0 0 74 196 1 1
    PRKCB PLCH1 0 0 61 218 1 1
    PRKCB CAT 0 0 265 265 1 1
    PRKCB GFI1 0 0 263 277 1 1
    PRKCB SGPP2 0 0 0 160 1 1
    PRKCB DUSP6 0 0 454 454 1 1
    PRKCB PDPK1 270 900 252 929 1 2
    PRKCB RASA1 0 650 128 731 1 1
    PRKCB BMPR2 213 0 611 704 1 1
    PRKCB SLC9A3R1 0 800 45 833 1 1
    PRKCB GRIA1 0 900 107 941 1 1
    PRKCB STXBP3 0 900 0 912 1 1
    PRKCB CHMP1A 0 0 46 214 1 1
    PRKCB AP2B1 0 900 0 900 1 1
    PRKCB NFATC2 0 0 187 219 1 1
    PRKCB CNN3 0 0 0 170 1 1
    PRKCB WASF1 0 0 102 215 1 1
    PRKCB SPOCK2 0 0 56 184 1 1
    PRKCB KCNN2 0 600 0 643 1 1
    PRKCB P2RX1 0 0 0 167 1 1
    PRKCB MITF 0 0 162 172 1 1
    PRKCB RRAGA 0 0 112 150 1 2
    PRKCB DGKB 0 0 57 162 1 1
    PRKCB JAK1 0 900 207 909 1 1
    PRKCB ST6GALNAC4 0 0 74 166 1 1
    PRKCB EPB41 213 0 0 253 1 1
    PRKCB SLC17A7 0 0 96 162 1 1
    PRKCB ARHGAP26 0 0 82 199 1 1
    PRKCB HMOX1 0 0 190 190 1 2
    PRKCB DNMT3L 0 0 270 270 1 1
    PRKCB RHOH 0 0 113 167 1 1
    PRKCB HSD17B2 0 0 49 163 1 1
    PRKCB RB1 270 0 90 378 1 2
    PRKCB GSTM4 0 0 155 168 1 1
    PRKCB CDKN1B 0 0 163 163 1 2
    PRKCB HECTD1 0 0 95 157 1 1
    PRKCB TSC2 0 0 171 171 1 2
    PRKCB ARHGAP15 0 0 0 162 1 1
    PRKCB VPS45 0 0 47 262 1 1
    PRKCB ADAM12 0 900 0 900 1 1
    PRKCB SRC 0 900 455 920 1 1
    PRKCB FAM117A 0 0 141 201 1 1
    PRKCB SMURF2 0 0 91 191 1 1
    PRKCB DOCK2 0 0 56 184 1 1
    PRKCB GRAP 0 0 134 244 1 1
    PRKCB MCU 0 0 150 227 1 1
    PRKCB CREB5 0 600 180 682 1 1
    PRKCB STAP1 0 0 109 152 1 1
    PRKCB SPTAN1 213 360 0 501 1 1
    PRKCB ZFPM2 0 0 0 209 1 1
    PRKCB YWHAB 0 0 69 243 1 1
    PRKCB OXT 0 0 143 193 1 1
    PRKCB PDE1B 0 0 0 173 1 1
    PRKCB ING2 0 0 262 278 1 1
    PRKCB TUFT1 0 0 49 193 1 1
    PRKCB ACLY 0 0 66 161 1 1
    PRKCB FRMPD2 0 0 0 200 1 1
    PRKCB TCL1A 0 0 181 181 1 1
    PRKCB ADCK4 0 0 96 152 1 1
    PRKCB FBXW11 0 0 90 230 1 1
    PRKCB MYO1A 0 0 0 177 1 1
    PRKCB CA10 0 0 53 246 1 1
    PRKCB PIKFYVE 0 0 57 156 1 1
    PRKCB MALT1 0 650 526 827 1 1
    PRKCB EMD 0 900 0 900 1 1
    PRKCB RASIP1 0 0 54 156 1 1
    PRKCB GSK3A 463 0 216 524 1 1
    PRKCB ITGB6 0 600 0 609 1 1
    PRKCB CR2 0 0 202 234 1 1
    PRKCB LOC102724488 0 0 145 176 1 1
    PRKCB LINGO3 0 0 0 169 1 1
    PRKCB TLR9 0 0 183 220 1 1
    PRKCB GZMK 0 0 95 253 1 1
    PRKCB CARD14 0 800 180 837 1 1
    PRKCB SYT14 0 0 142 270 1 1
    PRKCB ATF4 0 600 76 633 1 2
    PRKCB ERMN 0 0 60 198 1 1
    PRKCB SYT4 0 0 207 194 1 1
    PRKCB PRKCG 0 800 646 812 1 1
    PRKCB CD4 0 0 240 285 1 1
    PRKCB AKT1 445 0 560 495 1 2
    PRKCB PPARG 0 0 275 275 1 1
    PRKCB DUSP23 0 0 85 179 1 1
    PRKCB MKI67 213 0 0 244 1 1
    PRKCB CD48 0 0 0 151 1 1
    PRKCB SYNJ2BP-COX16 0 0 0 184 1 1
    PRKCB KCNJ6 0 0 72 212 1 1
    PRKCB DISC1 0 0 66 164 1 1
    PRKCB ATL2 0 0 61 317 1 1
    PRKCB PPP2R4 270 0 261 437 1 1
    PRKCB GMFG 0 0 62 154 1 1
    PRKCB SPTB 0 360 0 390 1 1
    PRKCB DCTN5 0 0 74 196 1 1
    PRKCB KCNAB2 0 0 0 177 1 1
    PRKCB IKBKB 682 900 431 973 1 1
    PRKCB PFKFB1 0 0 0 542 1 1
    PRKCB TMPO 0 900 57 901 1 1
    PRKCB ITPKA 0 0 137 286 1 1
    PRKCB GABBR1 0 0 105 214 1 1
    PRKCB PDZD11 0 0 0 184 1 1
    PRKCB CARD11 270 900 752 982 1 1
    PRKCB HLA-DRA 0 0 68 162 1 1
    PRKCB LPIN1 0 650 61 688 1 2
    PRKCB ZMYND8 213 0 435 536 1 1
    PRKCB CD81 0 0 156 174 1 1
    PRKCB BIN2 0 0 0 187 1 1
    PRKCB MYH11 0 0 73 210 1 1
    PRKCB CD72 0 0 180 210 1 1
    PRKCB SCN8A 0 0 76 172 1 1
    PRKCB OLR1 0 0 202 225 1 1
    PRKCB SRSF5 0 0 166 205 1 1
    PRKCB IL2 0 900 204 916 1 1
    PRKCB ABCC1 0 0 389 402 1 1
    PRKCB VAMP5 0 0 97 159 1 1
    PRKCB ZNF300 0 0 134 164 1 1
    PRKCB HLA-DPA1 0 0 72 167 1 1
    PRKCB MYO16 0 0 0 188 1 1
    PRKCB MAPT 270 0 162 438 1 2
    PRKCB SHC4 0 0 108 169 1 1
    PRKCB CAMK2B 0 0 253 182 1 1
    PRKCB PPM1A 270 0 0 270 1 1
    PRKCB PLA2G4F 0 600 0 614 1 1
    PRKCB MAPK11 0 0 125 163 1 1
    PRKCB DUSP1 0 0 181 181 1 1
    PRKCB LIN54 0 0 71 271 1 1
    PRKCB LNX2 0 0 0 184 1 1
    PRKCB HIST1H3E 0 0 305 320 1 1
    PRKCB MLST8 0 0 82 231 1 2
    PRKCB GNB3 0 650 45 659 1 1
    PRKCB CD3E 0 0 134 210 1 1
    PRKCB CLIP2 0 0 60 158 1 1
    PRKCB TAS1R3 0 0 0 172 1 1
    PRKCB PTH 0 0 99 264 1 1
    PRKCB CACNA1I 0 0 91 216 1 1
    PRKCB KRAS 0 900 243 925 1 1
    PRKCB ITGB2 270 0 126 423 1 1
    PRKCB MNDA 0 0 0 223 1 1
    PRKCB PRKAR1A 129 0 163 330 1 2
    PRKCB KCNG1 0 0 0 224 1 1
    PRKCB ARRDC5 0 0 0 152 1 1
    PRKCB FAF1 0 0 45 195 1 1
    PRKCB MYO1C 0 0 46 188 1 1
    PRKCB PPP1R1A 0 0 150 228 1 1
    PRKCB RNASE6 0 0 0 154 1 1
    PRKCB FRMD7 0 0 0 164 1 1
    PRKCB STAT5A 0 900 150 914 1 1
    PRKCB PON1 0 0 141 202 1 1
    PRKCB AQP4 0 0 81 183 1 1
    PRKCB SRSF10 0 0 398 398 1 1
    PRKCB PIK3CD 0 0 284 336 1 1
    PRKCB CEBPB 0 0 141 156 1 1
    PRKCB NOD2 0 0 81 209 1 1
    PRKCB CIITA 0 0 116 153 1 1
    PRKCB HABP4 213 0 66 287 1 1
    PRKCB MYO19 0 0 0 176 1 1
    PRKCB JAKMIP1 0 0 0 169 1 1
    PRKCB ARRDC3 0 0 0 258 1 1
    PRKCB RIMS3 0 0 58 196 1 1
    PRKCB GSK3B 600 0 317 665 1 2
    PRKCB RPS27A 128 0 49 193 1 1
    PRKCB CDKN2A 0 0 171 187 1 2
    PRKCB ARRB2 486 0 74 544 1 1
    PRKCB CACNA1H 0 0 217 353 1 1
    PRKCB PLCZ1 0 800 0 815 1 1
    PRKCB GNG3 0 650 150 731 1 1
    PRKCB ITPKB 0 0 152 194 1 1
    PRKCB RASGRF1 0 0 107 244 1 1
    PRKCB REN 0 0 335 349 1 1
    PRKCB TNFSF13B 0 0 303 303 1 1
    PRKCB ACE 0 0 340 340 1 1
    PRKCB CACNA2D3 0 0 141 212 1 1
    PRKCB RAB20 0 0 96 212 1 1
    PRKCB CYBB 0 0 297 420 1 1
    PRKCB GNG10 0 650 61 685 1 1
    PRKCB DLG3 0 0 0 167 1 1
    PRKCB MAL 0 0 0 165 1 1
    PRKCB PLA2G6 0 800 0 804 1 1
    PRKCB NLRP3 0 0 142 166 1 2
    PRKCB REL 0 0 241 240 1 1
    PRKCB CD53 0 0 108 339 1 1
    PRKCB PLD2 0 900 54 901 1 1
    PRKCB EGLN1 0 800 0 812 1 1
    PRKCB CASP3 0 800 307 855 1 2
    PRKCB RASGRP4 0 0 181 160 1 1
    PRKCB SMURF1 0 0 81 180 1 1
    PRKCB PTGS2 0 0 270 273 1 1
    PRKCB MYH7 0 0 46 205 1 1
    PRKCB NFATC1 0 0 172 171 1 1
    PRKCB TERF1 295 0 0 295 1 1
    PRKCB DRD3 270 0 95 425 1 2
    PRKCB RRAGB 0 0 85 233 1 2
    PRKCB NTRK3 0 0 155 159 1 1
    PRKCB CYTIP 0 0 0 266 1 1
    PRKCB TNFRSF11A 0 0 101 464 1 1
    PRKCB FPR1 0 0 93 151 1 1
    PRKCB GOPC 0 0 0 184 1 2
    PRKCB CD79A 0 0 465 486 1 1
    PRKCB GNB4 0 650 86 686 1 1
    PRKCB KIT 213 0 201 288 1 1
    PRKCB DACT3 0 0 0 167 1 1
    PRKCB NKAP 0 0 155 154 1 1
    PRKCB CCL3 0 0 137 168 1 1
    PRKCB CTSG 0 0 54 170 1 1
    PRKCB GAD2 0 0 0 184 1 1
    PRKCB DNER 0 0 0 155 1 1
    PRKCB ZIC4 0 0 0 187 1 1
    PRKCB FLT3 0 0 171 192 1 1
    PRKCB PPP3R1 0 0 163 195 1 1
    PRKCB UBASH3A 0 0 0 367 1 1
    PRKCB IL10 0 0 234 234 1 1
    PRKCB PA2G4 213 0 0 213 1 1
    PRKCB MRAS 0 600 0 600 1 1
    PRKCB KDM4C 0 0 305 305 1 1
    PRKCB IPCEF1 0 0 0 204 1 1
    PRKCB GDF15 117 0 54 163 1 1
    PRKCB DLG4 0 0 101 251 1 1
    PRKCB DGKI 0 0 72 184 1 1
    PRKCB MARCKS 463 900 396 965 1 1
    PRKCB SPHK1 0 900 107 915 1 2
    PRKCB PAG1 270 0 63 286 1 1
    PRKCB SPHK2 0 800 0 812 1 1
    PRKCB VSTM2B 0 0 0 164 1 1
    PRKCB ITM2A 0 0 0 210 1 1
    PRKCB SDC2 270 0 0 289 1 1
    PRKCB UBC 131 0 66 327 1 1
    PRKCB CNTNAP5 0 0 66 242 1 1
    PRKCB ATP2B1 0 0 124 185 1 1
    PRKCB NCF2 0 900 258 926 1 1
    PRKCB GRIP2 0 900 0 915 1 1
    PRKCB KCNN4 0 600 61 668 1 1
    PRKCB ADRB1 0 0 140 284 1 1
    PRKCB VAV1 0 0 283 360 1 1
    PRKCB NECAB3 0 0 0 156 1 1
    PRKCB VAMP3 0 0 112 299 1 1
    PRKCB PTH2 0 0 202 202 1 1
    PRKCB MYH15 0 0 0 165 1 1
    PRKCB TBP 0 0 74 219 1 1
    PRKCB FN1 74 0 325 348 1 1
    PRKCB PKN1 270 0 481 350 1 1
    PRKCB CAMK2A 103 0 343 282 1 2
    PRKCB ATP6AP1 0 800 81 810 1 1
    PRKCB RIPK4 486 0 531 631 1 1
    PRKCB HINT1 0 0 352 352 1 1
    PRKCB PRKCA 179 800 681 830 1 1
    PRKCB CYTH2 213 0 0 280 1 1
    PRKCB ADCY8 0 600 113 638 1 1
    PRKCB GPR176 0 0 95 153 1 1
    PRKCB ESR1 0 0 203 203 1 1
    PRKCB PDE10A 0 0 0 161 1 1
    PRKCB PLCXD3 0 0 134 302 1 1
    PRKCB HOMER1 0 0 108 163 1 1
    PRKCB TRPA1 0 0 0 287 1 1
    PRKCB POU2AF1 0 0 193 240 1 1
    PRKCB PDK4 0 0 61 205 1 1
    PRKCB INPP4A 0 0 107 158 1 1
    PRKCB RGS2 270 0 66 312 1 1
    PRKCB LMNB1 487 900 70 950 1 1
    PRKCB PLCD3 0 800 51 813 1 1
    PRKCB TNFAIP2 0 0 150 177 1 1
    PRKCB SLC6A3 0 800 213 835 1 1
    PRKCB TTF1 0 800 0 800 1 1
    PRKCB PLCD1 0 800 57 818 1 1
    PRKCB MYO7A 0 0 0 204 1 1
    PRKCB ILKAP 0 0 134 157 1 1
    PRKCB PRKD1 0 800 324 832 1 1
    PRKCB TNIK 0 0 75 224 1 1
    PRKCB PTPRA 0 0 122 209 1 1
    PRKCB PDK1 0 0 100 238 1 1
    PRKCB MYC 0 0 322 321 1 2
    PRKCB VWC2 0 0 125 150 1 1
    PRKCB SLC18A2 0 0 74 160 1 1
    PRKCB H1F0 270 0 64 298 1 1
    PRKCB PLCB3 0 600 67 671 1 1
    PRKCB USF1 0 0 57 202 1 1
    PRKCB TAB2 0 0 167 186 1 1
    PRKCB GPSM3 0 0 75 164 1 1
    PRKCB IGF1R 0 0 258 163 1 1
    PRKCB PPP3CB 0 0 275 321 1 1
    PRKCB CD300A 0 0 0 181 1 1
    PRKCB MYH10 0 0 66 226 1 1
    PRKCB MYLK4 0 0 146 183 1 1
    PRKCB ARRDC2 0 0 0 173 1 1
    PRKCB SPTBN2 0 360 0 384 1 1
    PRKCB TRAF2 0 0 143 174 1 1
    PRKCB GNAT3 0 0 0 200 1 1
    PRKCB OR5K3 0 0 280 291 1 1
    PRKCB ACACA 0 0 108 163 1 1
    PRKCB SYT11 0 0 123 167 1 1
    PRKCB CHST1 0 0 0 161 1 1
    PRKCB PIK3CA 0 0 265 298 1 2
    PRKCB PLCB2 0 600 160 748 1 1
    PRKCB PPP3CC 0 0 216 266 1 1
    PRKCB SLC6A1 0 0 119 171 1 1
    PRKCB ARCN1 117 0 68 153 1 1
    PRKCB CACNA1S 0 600 0 609 1 1
    PRKCB TAX1BP1 0 0 66 210 1 2
    PRKCB PARK7 0 0 57 201 1 1
    PRKCB KCNN3 0 600 67 653 1 1
    PRKCB UBD 0 0 67 178 1 1
    PRKCB SHANK1 0 0 0 264 1 1
    PRKCB PARD3 0 0 0 184 1 1
    PRKCB HIST1H1A 270 0 0 334 1 1
    PRKCB TNFRSF13B 0 0 166 213 1 1
    PRKCB NFE2L2 0 900 155 911 1 1
    PRKCB UBBP4 0 0 0 238 1 1
    PRKCB IKZF3 0 0 164 182 1 1
    PRKCB CARD10 0 800 261 853 1 1
    PRKCB MAP2K1 0 0 360 202 1 1
    PRKCB RBCK1 836 0 386 897 1 1
    PRKCB GRPR 0 0 0 216 1 1
    PRKCB GPM6B 0 0 0 165 1 1
    PRKCB PRKCE 0 500 503 532 1 1
    PRKCB SLC12A5 0 0 57 162 1 1
    PRKCB TUBA4A 117 0 66 155 1 1
    PRKCB MYD88 0 0 243 242 1 1
    PRKCB DECR1 0 900 0 900 1 1
    PRKCB SLC9A3R2 0 0 0 194 1 1
    PRKCB CRTAC1 0 0 0 161 1 1
    PRKCB PDZD4 0 0 66 254 1 1
    PRKCB TRAF1 0 0 102 153 1 1
    PRKCB GZMH 0 0 0 169 1 1
    PRKCB LMNA 0 900 70 906 1 1
    PRKCB SNAP23 0 0 193 260 1 1
    PRKCB PABPC1 0 0 0 194 1 1
    PRKCB LCP2 0 0 172 338 1 1
    PRKCB EDARADD 0 0 0 153 1 1
    PRKCB RASGRP2 0 0 150 294 1 1
    PRKCB ZFAND4 0 0 0 155 1 1
    PRKCB SCNN1B 0 0 445 445 1 1
    PRKCB LY86 0 0 57 225 1 1
    PRKCB CACNA1F 0 600 54 630 1 1
    PRKCB CTBP2 0 0 0 293 1 1
    PRKCB CYBA 0 0 212 212 1 1
    PRKCB FGR 0 0 185 215 1 1
    PRKCB PIN1 0 900 54 916 1 1
    PRKCB MPDZ 0 0 0 510 1 1
    PRKCB STAT3 0 0 321 321 1 2
    PRKCB CPT2 0 0 60 222 1 1
    PRKCB SCNN1G 0 0 410 410 1 1
    PRKCB RBBP6 0 0 107 280 1 1
    PRKCB GLT1D1 0 0 0 157 1 1
    PRKCB DLG2 0 0 107 304 1 1
    PRKCB IL1B 0 0 293 293 1 1
    PRKCB CACNG3 0 0 228 348 1 1
    PRKCB KCNIP2 0 0 96 204 1 1
    PRKCB PYGL 0 0 91 153 1 1
    PRKCB SIRT5 0 0 108 179 1 1
    PRKCB HCLS1 0 0 95 216 1 1
    PRKCB HIF1A 0 0 211 228 1 2
    PRKCB EDN1 0 0 375 375 1 1
    PRKCB GRIK3 0 0 91 176 1 1
    PRKCB ACVR1C 0 0 63 168 1 1
    PRKCB MAPK13 0 0 134 156 1 1
    PRKCB SCN1A 0 0 0 180 1 1
    PRKCB CDC73 0 0 70 213 1 1
    PRKCB FCGR3A 0 0 76 170 1 1
    PRKCB AFAP1 270 0 0 270 1 1
    PRKCB PRKAR2B 0 0 145 193 1 1
    PRKCB ELK1 0 900 0 900 1 1
    PRKCB ACSL5 117 0 0 155 1 1
    PRKCB SAMSN1 0 0 0 157 1 1
    PRKCB IBTK 270 0 72 342 1 1
    PRKCB PLA2G4A 0 600 207 669 1 1
    PRKCB GRIP1 0 900 0 916 1 1
    PRKCB NOTCH1 0 0 229 245 1 1
    PRKCB CD40LG 0 0 451 473 1 1
    PRKCB SULT1A1 0 0 486 485 1 1
    PRKCB POTEF 0 0 294 309 1 1
    PRKCB MYO1H 0 0 0 184 1 1
    PRKCB CALM1 0 0 218 264 1 1
    PRKCB MYO9B 0 0 0 191 1 1
    PRKCB IL6 0 0 334 334 1 1
    PRKCB NALCN 0 0 47 208 1 1
    PRKCB UCP2 0 0 154 153 1 1
    PRKCB ACTN4 0 0 73 230 1 1
    PRKCB RPS6 0 0 170 169 1 1
    PRKCB TNFRSF1A 270 0 150 352 1 1
    PRKCB DACT2 0 0 0 167 1 1
    PRKCB KCNA5 270 0 42 411 1 1
    PRKCB ACTR2 0 0 95 179 1 1
    PRKCB ADCY9 0 600 181 670 1 1
    PRKCB JHDM3C 0 0 305 305 1 1
    PRKCB PLCG2 0 900 558 959 1 1
    PRKCB SYT12 0 0 120 152 1 1
    PRKCB MYH3 0 0 0 204 1 1
    PRKCB BAP1 0 0 48 156 1 1
    PRKCB FBXO32 0 0 0 256 1 2
    PRKCB TRPC1 0 0 54 318 1 1
    PRKCB AKAP12 128 0 103 206 1 1
    PRKCB CCNB1 0 0 95 161 1 1
    PRKCB ANXA5 0 0 202 202 1 1
    PRKCB GRIA4 0 900 73 920 1 1
    PRKCB GRIA2 0 900 150 944 1 1
    PRKCB PDE11A 0 0 45 211 1 1
    PRKCB DTNA 0 0 218 235 1 1
    PRKCB RGS4 0 0 123 210 1 1
    PRKCB ITPR2 0 800 156 841 1 1
    PRKCB PHLPP1 282 0 150 372 1 1
    PRKCB SLC9A1 0 800 129 822 1 1
    PRKCB CABIN1 0 900 0 900 1 1
    PRKCB BCL2L1 0 0 291 290 1 2
    PRKCB MYO1D 0 0 0 202 1 1
    PRKCB RNPS1 0 0 81 173 1 1
    PRKCB TUBB4A 0 0 96 169 1 1
    PRKCB MAPK8IP1 0 0 71 217 1 1
    PRKCB HMGB2 190 0 0 238 1 1
    PRKCB SLC5A4 0 0 151 150 1 1
    PRKCB RADIL 0 0 53 157 1 1
    PRKCB OLIG1 0 0 0 154 1 1
    PRKCB PRPF38A 0 0 62 265 1 1
    PRKCB PABPC3 0 0 0 194 1 1
    PRKCB TLR4 0 0 260 269 1 1
    PRKCB NOS2 0 0 112 194 1 1
    PRKCB RPS6KA5 0 0 138 153 1 1
    PRKCB RAP1A 0 0 148 179 1 1
    PRKCB MAPK12 0 0 159 164 1 1
    PRKCB GRIN2C 0 0 67 168 1 1
    PRKCB EARS2 0 0 42 212 1 1
    PRKCB LEMD2 0 900 0 900 1 1
    PRKCB PLCB4 0 600 218 724 1 1
    PRKCB IL10RA 0 0 104 209 1 1
    PRKCB BCL2L11 0 0 154 153 1 1
    PRKCB PPP1R16B 0 0 90 334 1 1
    PRKCB DVL3 0 0 0 172 1 1
    PRKCB ADRA1A 0 0 124 161 1 1
    PRKCB PLCG1 0 900 340 939 1 1
    PRKCB ITPR3 0 800 194 843 1 1
    PRKCB MEF2BNB 0 0 97 248 1 1
    PRKCB DTX1 0 0 64 210 1 1
    PRKCB EVI2B 0 0 0 155 1 1
    PRKCB AKT1S1 0 0 117 256 1 1
    PRKCB CASP1 0 0 161 179 1 2
    PRKCB PHF21A 0 0 416 416 1 1
    PRKCB SNCA 0 0 92 292 1 2
    PRKCB SLC16A3 0 0 54 261 1 1
    PRKCB CHEK1 117 0 140 153 1 1
    PRKCB CD74 0 0 155 247 1 1
    PRKCB VRK2 0 0 64 163 1 1
    PRKCB MAP2K3 0 0 171 165 1 1
    PRKCB CAV1 0 0 215 220 1 1
    PRKCB CD8A 0 0 203 227 1 1
    PRKCB IGFBP3 0 0 127 181 1 1
    PRKCB SYNJ2BP 0 0 0 184 1 1
    PRKCB ARHGEF2 0 0 75 178 1 1
    PRKCB SSTR3 0 0 0 173 1 1
    PRKCB CREB3 0 600 61 616 1 1
    PRKCB MMP2 0 0 181 181 1 1
    PRKCB GRIN2D 128 0 109 243 1 1
    PRKCB TCF7 0 0 73 172 1 1
    PRKCB RBFOX1 0 0 0 154 1 1
    PRKCB CRK 0 900 97 907 1 1
    PRKCB RASD1 0 0 96 152 1 1
    PRKCB LCK 0 900 282 919 1 1
    PRKCB KDM4A 0 0 295 295 1 1
    PRKCB ATP2B3 0 0 0 151 1 1
    PRKCB CSNK1A1 0 0 257 291 1 1
    PRKCB ERN2 0 0 0 228 1 1
    PRKCB CD69 0 0 150 262 1 1
    PRKCB CCR5 0 0 90 170 1 1
    PRKCB CENPJ 0 0 0 214 1 1
    PRKCB TRPM5 0 0 0 159 1 1
    PRKCB FYB 0 0 134 306 1 1
    PRKCB AKAP9 0 0 702 702 1 1
    PRKCB MYH9 0 0 105 258 1 1
    PRKCB MS4A1 0 0 75 163 1 1
    PRKCB ATRN 0 0 67 165 1 1
    PRKCB ADORA2A 0 0 96 152 1 1
    PRKCB PDK2 0 900 95 920 1 1
    PRKCB TCF7L1 0 0 97 192 1 1
    PRKCB CPEB4 0 0 82 197 1 1
    PRKCB INSR 0 800 269 826 1 1
    PRKCB RHOA 0 0 420 432 1 1
    PRKCB TOMM40 0 0 96 160 1 1
    PRKCB GNG7 0 650 0 692 1 1
    PRKCB KDM1A 270 0 397 551 1 1
    PRKCB CD3D 0 0 123 209 1 1
    PRKCB TMEM189 0 0 113 240 1 1
    PRKCB CXCL12 0 0 163 163 1 1
    PRKCB ACTB 0 0 325 368 1 1
    PRKCB INS 0 0 467 467 1 1
    PRKCB CLDN5 0 0 150 171 1 1
    PRKCB NEFH 0 0 52 153 1 1
    PRKCB CD8B 0 0 140 212 1 1
    PRKCB CAV2 0 0 450 474 1 1
    PRKCB RPS6KA6 0 0 84 155 1 1
    PRKCB DNMT1 0 0 96 159 1 1
    PRKCB GLP1R 0 0 132 151 1 1
    PRKCB ITGB7 213 600 72 730 1 1
    PRKCB CD40 0 0 298 298 1 1
    PRKCB ROS1 0 0 108 151 1 1
    PRKCB KEAP1 0 900 120 908 1 2
    PRKCB PAX5 0 0 158 173 1 1
    PRKCB ANGPT1 0 0 134 152 1 1
    PRKCB SYT6 270 0 136 359 1 1
    PRKCB GRASP 0 0 0 205 1 1
    PRKCB PDGFD 0 0 136 190 1 1
    PRKCB SLC9A9 0 0 45 190 1 1
    PRKCB FCGR2B 0 0 180 228 1 1
    PRKCB GNG2 0 650 82 698 1 1
    PRKCB IL3 0 0 171 222 1 1
    PRKCB TFEB 0 0 294 302 1 2
    PRKCB PAX8 0 800 410 877 1 1
    PRKCB MYO9A 0 0 52 202 1 1
    PRKCB HPGDS 0 0 150 184 1 1
    PRKCB TMTC1 0 0 101 208 1 1
    PRKCB FBXW7 0 0 90 240 1 1
    PRKCB SETD1A 0 0 358 372 1 1
    PRKCB KDM1B 0 0 357 371 1 1
    PRKCB MYO1G 0 0 0 309 1 1
    PRKCB SORCS3 0 0 95 260 1 1
    PRKCB KNG1 0 0 193 193 1 1
    PRKCB CASP8 0 0 189 189 1 2
    PRKCB IGLL5 0 0 182 205 1 1
    PRKCB BAG2 129 0 0 181 1 1
    PRKCB GNB5 0 650 60 670 1 1
    PRKCB ITGB1 0 600 107 672 1 1
    PRKCB ADRB3 0 0 66 158 1 1
    PRKCB ADD3 0 0 66 206 1 1
    PRKCB PLEKHH3 0 0 0 191 1 1
    PRKCB ADCY5 0 600 180 665 1 1
    PRKCB MLLT4 0 0 73 153 1 1
    PRKCB HVCN1 0 0 102 166 1 1
    PRKCB PLCL2 0 0 57 162 1 1
    PRKCB DDX58 270 0 122 349 1 1
    PRKCB CHRM3 0 0 150 188 1 1
    PRKCB YWHAG 270 0 123 345 1 1
    PRKCB CSRNP2 0 0 112 209 1 1
    PRKCB PLG 0 0 173 173 1 1
    PRKCB RNF31 270 0 134 340 1 1
    PRKCB PLCD4 0 800 180 845 1 1
    PRKCB PIK3R5 0 0 194 277 1 1
    PRKCB DPP4 0 0 149 150 1 1
    PRKCB CCNB3 0 0 70 228 1 1
    PRKCB CCL4 0 0 142 180 1 1
    PRKCB MAVS 0 0 108 260 1 1
    PRKCB HIST2H3PS2 0 0 180 197 1 1
    PRKCB IFIH1 0 0 106 198 1 1
    PRKCB SMARCB1 0 0 67 210 1 1
    PRKCB CISH 213 0 87 335 1 1
    PRKCB CD244 0 0 66 161 1 1
    PRKCB FKBP1A 0 0 134 156 1 2
    PRKCB NR3C1 0 0 128 182 1 1
    PRKCB IL2RG 0 900 131 916 1 1
    PRKCB RCSD1 0 0 0 151 1 1
    PRKCB CTGF 0 0 233 232 1 1
    PRKCB MLLT11 0 0 73 163 1 1
    PRKCB IGHV4-38-2 0 0 235 235 1 1
    PRKCB SHANK2 0 0 126 305 1 1
    PRKCB RASSF2 0 0 74 168 1 1
    PRKCB ADIPOQ 0 0 195 195 1 1
    PRKCB TBXA2R 0 900 134 911 1 1
    PRKCB LDB3 0 0 0 218 1 1
    PRKCB CD79B 0 0 501 530 1 1
    PRKCB HLA-DQA1 0 0 93 156 1 1
    PRKCB MAPK9 0 0 244 156 1 2
    PRKCB TLR7 0 0 123 155 1 1
    PRKCB ZNF592 0 0 0 169 1 1
    PRKCB RPS6KA3 0 0 166 173 1 1
    PRKCB OGG1 0 0 357 357 1 1
    PRKCB TGM7 0 0 90 152 1 1
    PRKCB CASP9 0 0 224 224 1 1
    PRKCB ITPR1 0 800 273 865 1 2
    PRKCB RPS6KA4 117 0 66 203 1 1
    PRKCB SOS2 0 0 117 155 1 1
    PRKCB NRXN2 0 0 81 193 1 1
    PRKCB FARP2 0 0 0 163 1 1
    PRKCB AKR1B1 0 0 456 456 1 1
    PRKCB PDE2A 0 0 54 197 1 1
    PRKCB CELF2 0 0 0 175 1 1
    PRKCB TYR 0 800 202 837 1 1
    PRKCB KHDRBS3 0 0 67 165 1 1
    PRKCB LRMP 0 0 74 261 1 1
    PRKCB GNAS 0 900 134 913 1 1
    PRKCB FBXO7 270 0 0 270 1 2
    PRKCB SLC8A3 0 0 116 188 1 1
    PRKCB DAB2 270 0 0 279 1 1
    PRKCB DLG5 0 0 55 259 1 1
    PRKCB BPTF 0 0 306 322 1 1
    PRKCB RPTOR 0 0 154 160 1 2
    PRKCB BDNF 0 0 181 199 1 2
    PRKCB CD44 0 0 184 183 1 1
    PRKCB GNAI2 0 600 220 694 1 1
    PRKCB SYT16 0 0 145 228 1 1
    PRKCB PDLIM5 270 0 514 670 1 1
    PRKCB OXTR 0 0 108 176 1 1
    PRKCB SNAP25 0 0 108 267 1 1
    PRKCB EPB41L2 0 360 0 374 1 1
    PRKCB RAVER1 0 0 82 152 1 1
    PRKCB SRSF4 0 0 102 288 1 1
    PRKCB DDX3X 0 0 82 239 1 1
    PRKCB PLA2G4D 0 600 0 614 1 1
    PRKCB TRAF3IP3 0 0 134 220 1 1
    PRKCB FGF2 0 0 193 193 1 1
    PRKCB RELB 0 0 229 228 1 2
    PRKCB BCL2A1 0 0 166 198 1 1
    PRKCB PLEKHA4 270 0 0 270 1 1
    PRKCB IFNAR1 0 0 430 430 1 1
    PRKCB SOS1 0 0 142 221 1 1
    PRKCB GNG13 0 650 73 690 1 1
    PRKCB AXIN2 0 0 96 205 1 1
    PRKCB ITGA3 0 0 0 367 1 1
    PRKCB IGF1 0 0 286 286 1 1
    PRKCB MAPK1 0 900 417 932 1 2
    PRKCB PPP2R1A 0 600 107 643 1 1
    PRKCB CCND3 0 0 170 169 1 1
    PRKCB BTK 462 0 849 719 1 1
    PRKCB PKM 0 0 274 307 1 1
    PRKCB ADRA1D 0 0 130 166 1 1
    PRKCB RRAD 213 0 58 226 1 1
    PRKCB RAB33A 0 0 105 248 1 1
    PRKCB RAPGEF5 0 0 57 223 1 1
    PRKCB EIF4E 213 0 171 363 1 1
    PRKCB ETV6 0 0 113 177 1 1
    PRKCB PPP2CA 0 600 95 653 1 1
    PRKCB PRKDC 0 0 108 189 1 2
    PRKCB LRGUK 0 0 0 184 1 1
    PRKCB CCND1 0 0 270 270 1 1
    PRKCB NOS3 0 0 460 471 1 1
    PRKCB ACTN1 0 0 203 234 1 1
    PRKCB ATP2B2 0 0 155 260 1 1
    PRKCB BLNK 0 0 505 517 1 1
    PRKCB NCF1 868 900 475 992 1 1
    PRKCB GCM2 0 0 0 150 1 1
    PRKCB FAU 0 0 0 197 1 1
    PRKCB ANXA2 213 0 112 271 1 1
    PRKCB ADRA2C 0 650 48 665 1 1
    PRKCB CD19 0 0 271 322 1 1
    PRKCB ADCY2 0 600 371 759 1 1
    PRKCB ADD1 0 0 73 212 1 1
    PRKCB PHLPP2 282 0 54 297 1 1
    PRKCB ANXA7 213 0 66 233 1 2
    PRKCB PITPNM2 0 0 0 160 1 1
    PRKCB CD38 0 800 172 837 1 1
    PRKCB MAP2K2 0 0 260 171 1 1
    PRKCB GNB2L1 835 0 941 990 1 1
    PRKCB MYO1B 0 0 59 193 1 1
    PRKCB PLCE1 0 800 66 823 1 1
    PRKCB MYH2 0 0 76 196 1 1
    PRKCB UBB 131 0 0 309 1 1
    PRKCB PECAM1 0 0 171 211 1 1
    PRKCB PTK2B 0 900 229 916 1 1
    PRKCB RUNX1 0 900 0 901 1 1
    PRKCB STX19 0 0 95 159 1 1
    PRKCB CCNE1 0 0 102 158 1 1
    PRKCB LST1 213 0 0 251 1 1
    PRKCB LCP1 0 0 49 160 1 1
    PRKCB ENSG00000264813 0 0 325 325 1 1
    PRKCB GRIK5 0 0 90 178 1 1
    PRKCB INADL 0 0 0 510 1 1
    PRKCB PACSIN1 0 0 81 160 1 1
    PRKCB ATF6B 0 600 0 600 1 1
    PRKCB RAC2 0 0 260 322 1 1
    PRKCB STXBP2 0 0 69 231 1 1
    PRKCB KDR 0 0 289 152 1 2
    PRKCB CACNA1A 0 800 75 817 1 1
    PRKCB PRKD3 0 800 204 823 1 1
    PRKCB PTPN6 0 0 206 239 1 1
    PRKCB ADIPOR2 0 0 59 203 1 1
    PRKCB TBK1 0 0 89 175 1 2
    PRKCB PRKD2 0 800 123 818 1 1
    PRKCB ZNF488 0 0 158 251 1 1
    PRKCB ADCY4 0 600 52 608 1 1
    PRKCB PITPNB 0 0 0 166 1 1
    PRKCB CNN1 0 0 0 155 1 1
    PRKCB TRPV4 0 800 53 802 1 1
    PRKCB PRKCD 274 800 570 858 1 2
    PRKCB TIAM1 270 0 95 442 1 1
    PRKCB STAT5B 0 900 155 914 1 1
    PRKCB TGFB1 0 0 194 207 1 1
    PRKCB VDAC1 0 0 140 158 1 2
    PRKCB IRF8 0 0 150 245 1 1
    PRKCB CDC42 0 0 244 272 1 1
    PRKCB EIF6 213 0 46 217 1 1
    PRKCB ITGA6 0 0 112 235 1 1
    PRKCB TNFSF11 0 0 184 183 1 1
    PRKCB CBFB 0 900 0 900 1 1
    PRKCB APOE 0 0 245 261 1 1
    PRKCB BBOX1 0 0 61 274 1 1
    PRKCB FOXO3 0 0 235 270 1 2
    PRKCB SLC2A4 0 0 285 284 1 1
    PRKCB EWSR1 0 0 240 254 1 1
    PRKCB HTR2A 0 0 139 182 1 1
    PRKCB P2RY13 0 0 67 187 1 1
    PRKCB JMJD7-PLA2G4B 0 600 0 638 1 1
    PRKCB CORO1A 0 0 94 273 1 1
    PRKCB SYT3 0 0 166 204 1 1
    PRKCB DNAJB1 0 0 60 156 1 2
    PRKCB CAMK2D 0 0 210 156 1 1
    PRKCB CD52 0 0 107 211 1 1
    PRKCB HSP90AB1 129 0 85 256 1 2
    PRKCB HRH2 0 0 0 153 1 1
    PRKCB RBBP5 0 0 53 199 1 1
    PRKCB CYLD 0 0 150 167 1 1
    PRKCB EIF4EBP1 0 0 194 235 1 1
    PRKCB PDE5A 0 0 0 161 1 1
    PRKCB SPTA1 0 360 0 394 1 1
    PRKCB GRM5 213 0 113 328 1 1
    PRKCB BCL6 0 0 270 270 1 1
    PRKCB GJA1 213 0 181 412 1 1
    PRKCB PPP3CA 0 0 282 384 1 1
    PRKCB MYH4 0 0 0 202 1 1
    PRKCB NGF 0 0 156 166 1 1
    PRKCB VEGFB 0 0 134 196 1 1
    PRKCB PDE4B 0 0 135 224 1 1
    PRKCB ITM2B 0 0 48 152 1 1
    PRKCB PIK3R6 0 0 76 171 1 1
    PRKCB SYNGAP1 0 0 181 407 1 1
    PRKCB GPR183 0 0 139 190 1 1
    PRKCB F13A1 0 0 60 187 1 1
    PRKCB SUMO1 0 0 134 162 1 1
    PRKCB INPP5D 0 900 142 915 1 1
    PRKCB ATP2A3 0 0 117 314 1 1
    PRKCB WDTC1 0 0 0 216 1 1
    PRKCB VCAM1 0 0 289 337 1 1
    PRKCB PPP1R9B 0 0 66 221 1 1
    PRKCB SPIB 0 0 174 192 1 1
    PRKCB AP2M1 0 900 95 915 1 1
    PRKCB GRIK1 0 0 118 182 1 1
    PRKCB NOX4 0 0 286 286 1 1
    PRKCB DGKG 0 0 54 192 1 1
    PRKCB CD247 0 0 140 230 1 1
    PRKCB CREB3L4 0 600 95 626 1 1
    PRKCB NLRC4 0 0 57 175 1 2
    PRKCB DUOX1 0 0 161 173 1 1
    PRKCB AHI1 0 0 0 188 1 1
    PRKCB WAS 0 0 112 193 1 1
    PRKCB CD86 0 0 158 244 1 1
    PRKCB GNAI3 0 600 0 618 1 2
    PRKCB DGKE 0 0 51 223 1 1
    PRKCB ADCY3 0 600 45 618 1 1
    PRKCB CHRM4 0 0 71 150 1 1
    PRKCB EEF2K 0 800 55 838 1 2
    PRKCB DERL1 117 0 0 160 1 1
    PRKCB STXBP1 213 0 113 422 1 1
    PRKCB PICK1 0 900 454 945 1 1
    PRKCB GNAO1 0 0 193 260 1 1
    PRKCB GRIN2B 213 0 134 515 1 1
    PRKCB LRRK2 0 0 94 165 1 2
    PRKCB TRAF3 0 0 194 213 1 2
    PRKCB PRKCH 0 500 322 520 1 1
    PRKCB SLC5A2 0 0 155 154 1 1
    PRKCB PIK3CB 0 0 136 175 1 1
    PRKCB TLR2 0 0 193 216 1 1
    PRKCB HIST1H3J 270 0 0 285 1 1
    PRKCB CAMK4 0 0 236 182 1 1
    PRKCB MYH13 0 0 0 165 1 1
    PRKCB MYO3B 0 0 0 412 1 1
    PRKCB NRAS 0 800 194 836 1 1
    PRKCB AVPR1A 0 0 140 167 1 1
    PRKCB TFE3 0 0 162 225 1 1
    PRKCB TOP2B 0 0 0 239 1 1
    PRKCB SOD2 0 0 150 169 1 1
    PRKCB ADRBK1 678 0 454 728 1 1
    PRKCB DUSP3 0 0 96 260 1 1
    PRKCB FOXO1 0 0 234 234 1 2
    PRKCB GNGT2 0 650 53 693 1 1
    PRKCB AIFM3 0 0 0 188 1 1
    PRKCB YWHAZ 0 0 123 171 1 1
    PRKCB FOS 0 800 322 858 1 1
    PRKCB SUCLG2 0 0 150 229 1 1
    PRKCB PTPN11 213 0 156 311 1 1
    PRKCB GNG5 0 650 211 732 1 1
    PRKCB AJUBA 0 0 82 160 1 1
    PRKCB CPNE5 0 0 0 157 1 1
    PRKCB PLA2G4B 0 600 0 638 1 1
    PRKCB HCK 0 0 170 197 1 1
    PRKCB NDRG3 0 0 54 153 1 1
    PRKCB PSMD3 0 0 0 216 1 1
    PRKCB KCNJ10 0 0 0 289 1 1
    PRKCB PRDM1 0 0 213 213 1 1
    PRKCB TRPV5 0 800 0 806 1 1
    PRKCB ITGAX 0 0 96 189 1 1
    PRKCB BLK 0 0 218 172 1 1
    PRKCB MYH1 0 0 54 212 1 1
    PRKCB EPB42 0 0 307 307 1 1
    PRKCB CRLF3 0 0 93 188 1 1
    PRKCB SST 0 0 89 164 1 1
    PRKCB SH2D1A 0 0 108 182 1 1
    PRKCB CHUK 680 900 261 970 1 1
    PRKCB WNT2 0 0 94 150 1 1
    PRKCB PRKCQ 0 800 391 822 1 2
    PRKCB PTPN5 0 0 74 161 1 1
    PRKCB BCAR1 0 900 54 904 1 1
    PRKCB ALOX5 0 0 90 170 1 1
    PRKCB BAIAP2 0 0 123 157 1 1
    PRKCB NOTCH2 0 0 134 152 1 1
    PRKCB USH1C 0 0 0 189 1 1
    PRKCB GRM1 0 0 103 192 1 1
    PRKCB TRPC4 0 0 74 332 1 1
    PRKCB NR2C2 270 0 44 349 1 1
    PRKCB CD5 213 0 214 386 1 1
    PRKCB CD28 0 0 209 256 1 1
    PRKCB GABRB3 0 0 111 196 1 1
    PRKCB GNA15 0 0 96 194 1 1
    PRKCB LNX1 0 0 0 219 1 1
    PRKCB PITPNM3 0 0 0 160 1 1
    PRKCB MYH8 0 0 71 253 1 1
    PRKCB GAPVD1 0 0 56 166 1 1
    PRKCB SEC24A 117 0 95 198 1 1
    PRKCB SAP30BP 0 0 96 158 1 1
    PRKCB FCER1G 0 0 64 161 1 1
    PRKCB TRAF7 0 0 74 213 1 1
    PRKCB PDZD3 0 0 0 184 1 1
    PRKCB CYFIP2 0 0 81 223 1 1
    PRKCB MBP 270 0 101 389 1 1
    PRKCB PTEN 0 0 309 309 1 2
    PRKCB HIST1H3A 270 0 0 285 1 1
    PRKCB MAPK7 0 0 126 156 1 1
    PRKCB VEGFA 0 0 466 465 1 1
    PRKCB IRF4 0 0 260 310 1 1
    PRKCB AP2A1 0 900 0 906 1 1
    PRKCB MAPK10 0 0 170 197 1 2
    PRKCB MAPK14 0 0 231 215 1 1
    PRKCB RASAL2 0 0 0 203 1 1
    PRKCB NFKBIA 0 900 308 929 1 1
    PRKCB LEP 0 0 207 207 1 1
    PRKCB SYK 0 0 623 341 1 1
    PRKCB S1PR1 0 0 103 208 1 1
    PRKCB PPP1R9A 0 0 0 152 1 1
    PRKCB HIST1H3C 0 0 269 285 1 1
    PRKCB EFHD2 0 0 203 203 1 1
    PRKCB CA4 0 0 294 334 1 1
    PRKCB GNAI1 0 600 181 673 1 1
    PRKCB NRGN 213 0 136 400 1 1
    PRKCB NRXN1 0 0 181 245 1 1
    PRKCB SHC1 0 0 593 593 1 1
    PRKCB ATM 0 0 180 197 1 1
    PRKCB KCNA3 0 0 0 174 1 1
    PRKCB EZR 0 800 57 803 1 1
    PRKCB HIST1H1C 131 0 49 151 1 1
    PRKCB DFNB31 0 0 0 184 1 1
    PRKCB GABRA2 0 0 61 204 1 1
    PRKCB NECAB1 0 0 0 173 1 1
    PRKCB ITGB4 0 600 69 623 1 1
    PRKCB PARVG 0 0 0 163 1 1
    PRKCB GFAP 0 0 75 157 1 2
    PRKCB ACTG1 0 0 151 169 1 1
    PRKCB ITGB5 0 600 112 635 1 1
    PRKCB IKZF1 0 0 181 402 1 1
    PRKCB SYT2 0 0 155 162 1 1
    PRKCB TAC1 0 0 137 245 1 1
    PRKCB TJP1 0 0 193 193 1 1
    PRKCB EGLN2 0 800 0 812 1 1
    PRKCB TGFBR2 0 0 166 183 1 1
    PRKCB ADAM17 0 900 63 902 1 1
    PRKCB NFKBIB 0 0 147 182 1 1
    PRKCB TTC19 0 0 0 153 1 1
    PRKCB MYO1F 0 0 47 159 1 1
    PRKCB WDFY4 0 0 90 220 1 1
    PRKCB ISG15 0 0 0 155 1 1
    PRKCB ANXA6 0 0 453 453 1 1
    PRKCB HSPB1 129 0 142 220 1 1
    PRKCB TGFBR1 0 0 166 183 1 1
    PRKCB OSBPL9 0 0 159 158 1 1
    PRKCB RCOR1 0 0 326 336 1 1
    PRKCB CCR7 0 0 141 172 1 1
    PRKCB IKBKG 178 900 253 934 1 1
    PRKCB MAP4K4 0 0 170 258 1 1
    PRKCB AP2S1 0 900 0 906 1 1
    PRKCB CASR 463 0 48 488 1 1
    PRKCB VTN 213 0 66 251 1 1
    PRKCB NCAM1 270 0 71 456 1 1
    PRKCB ATP8A1 0 0 0 164 1 1
    PRKCB PPP1R14A 0 900 181 917 1 1
    PRKCB CACNA1E 0 0 134 225 1 1
    PRKCB LIG1 270 0 0 270 1 1
    PRKCB SOD3 0 0 95 179 1 1
    PRKCB RPS6KA1 0 0 281 201 1 1
    PRKCB SKIL 0 0 92 451 1 1
    PRKCB PPP1CA 270 0 158 460 1 1
    PRKCB AGAP1 0 0 75 160 1 1
    PRKCB HMGB1 0 0 108 233 1 2
    PRKCB MAPK6 213 0 74 264 1 1
    PRKCB GNG8 0 650 81 701 1 1
    PRKCB LYN 486 800 517 918 1 1
    PRKCB ITGAM 0 0 141 284 1 1
    PRKCB GNA11 0 0 93 198 1 1
    PRKCB DGKA 0 0 0 207 1 1
    PRKCB RGS1 0 0 0 165 1 1
    PRKCB MPP2 0 0 97 181 1 1
    PRKCB MCL1 0 0 218 218 1 2
    PRKCB SIRT1 0 0 211 217 1 2
    PRKCB MAPK8IP3 0 0 85 245 1 1
    PRKCB SPI1 0 0 123 272 1 1
    PRKCB TP53BP1 0 0 306 306 1 1
    PRKCB NOX1 0 0 260 276 1 1
    PRKCB PRKAG2 0 0 120 263 1 1
    PRKCB SASH3 0 0 140 273 1 1
    PRKCB FUS 0 0 291 290 1 1
    PRKCB MYO10 0 0 0 191 1 1
    PRKCB ITGB3 270 600 67 744 1 1
    PRKCB WDR18 0 0 0 161 1 1
    PRKCB TLR8 0 0 108 161 1 1
    PRKCB GRIN1 128 0 0 443 1 1
    PRKCB TIA1 0 0 0 181 1 1
    PRKCB EPB41L4A 0 0 67 208 1 1
    PRKCB CAMK2G 0 0 293 188 1 1
    PRKCB PPP5D1 0 0 0 156 1 1
    PRKCB LAPTM5 0 0 66 177 1 1
    PRKCB CBX5 0 0 73 259 1 1
    PRKCB ILK 0 0 180 176 1 1
    PRKCB WNT5A 0 900 165 912 1 1
    PRKCB PLCL1 0 0 61 175 1 1
    PRKCB PPP5C 0 0 46 161 1 1
    PRKCB SLC25A12 0 0 107 243 1 1
    PRKCB PPARGC1A 0 0 203 274 1 1
    PRKCB NLGN2 0 0 113 235 1 1
    PRKCB EGLN3 0 800 0 821 1 1
    PRKCB PIK3R3 0 0 195 283 1 1
    PRKCB DVL1 0 0 0 168 1 1
    PRKCB GNAQ 0 0 210 311 1 1
    PRKCB WDR64 0 0 143 294 1 1
    PRKCB PIM1 0 0 90 151 1 1
    PRKCB RICTOR 0 0 203 239 1 2
    PRKCB SLC15A4 0 0 115 155 1 1
    PRKCB CACNB4 0 0 66 203 1 1
    PRKCB MICU1 0 0 90 180 1 1
    PRKCB IL2RA 0 0 101 157 1 1
    PRKCB ARHGAP1 0 0 45 258 1 1
    PRKCB VAPA 0 0 83 280 1 1
    PRKCB CLEC11A 0 0 154 167 1 1
    PRKCB MYO15A 0 0 0 191 1 1
    PRKCB TFEC 0 0 155 205 1 1
    PRKCB LEMD3 117 900 0 909 1 1
    PRKCB INHBA 0 0 70 169 1 1
    PRKCB SDK1 0 0 49 215 1 1
    PRKCB FLNA 0 0 113 151 1 1
    PRKCB PDZRN4 0 0 100 156 1 1
    PRKCB TCL1B 0 0 181 181 1 1
    PRKCB DUSP4 0 0 112 174 1 1
    PRKCB FBXL16 0 0 74 173 1 1
    PRKCB GNG11 0 650 44 679 1 1
    PRKCB GNG4 0 650 138 722 1 1
    PRKCB GNG12 0 650 104 696 1 1
    PRKCB DAB2IP 0 0 0 203 1 2
    PRKCB MYL9 0 0 144 164 1 1
    PRKCB TOP2A 463 0 47 577 1 1
    PRKCB OASL 0 0 0 155 1 1
    PRKCB SYT13 0 0 154 185 1 1
    PRKCB RASGRP1 0 0 271 206 1 1
    PRKCB MPP6 0 0 108 171 1 1
    PRKCB TP53 0 0 390 390 1 2
    PRKCB MYH14 0 0 62 223 1 1
    PRKCB HS3ST2 0 0 54 187 1 1
    PRKCB EGFR 270 900 321 935 1 1
    PRKCB PPP1CC 0 0 173 300 1 1
    PRKCB SLC2A1 117 0 232 292 1 1
    PRKCB PFKFB2 0 0 0 796 1 1
    PRKCB CARD9 0 0 140 161 1 1
    PRKCB NELL2 0 0 99 183 1 1
    PRKCB PLA2G4E 0 600 0 614 1 1
    PRKCB NCOR2 0 0 98 173 1 1
    PRKCB RAF1 0 900 252 911 1 2
    PRKCB APAF1 0 0 108 163 1 1
    PRKCB CACNA1D 0 600 155 655 1 1
    PRKCB SHC3 0 0 112 193 1 1
    PRKCB HIST1H1B 270 0 0 281 1 1
    PRKCB JAK2 0 0 262 157 1 1
    PRKCB PLA2G4C 0 600 74 624 1 1
    PRKCB NR4A1 0 0 134 198 1 1
    PRKCB ADCY1 0 600 193 683 1 1
    PRKCB ATP2B4 0 0 203 256 1 1
    PRKCB TMEM108 0 0 90 250 1 1
    PRKCB SEMA3D 0 0 160 167 1 1
    PRKCB HUWE1 117 0 47 155 1 1
    PRKCB CALM3 0 0 213 259 1 1
    PRKCB MYO7B 0 0 0 191 1 1
    PRKCB MYH6 0 0 81 234 1 1
    PRKCB MCOLN1 0 0 180 179 1 1
    PRKCB GNGT1 0 900 81 912 1 1
    PRKCB RASGRP3 488 0 294 558 1 1
    PRKCB ITGB8 0 600 95 628 1 1
    PRKCB DLGAP1 0 0 0 173 1 1
    PRKCB PDZK1 0 0 0 184 1 1
    PRKCB GALNTL5 0 0 69 172 1 1
    PRKCB VRK1 0 0 113 177 1 1
    PRKCB VAV3 0 0 137 155 1 1
    PRKCB FZD4 0 900 74 903 1 1
    PRKCB ASAP1 0 0 0 233 1 1
    PRKCB CXCL8 0 0 261 261 1 1
    PRKCB EGR1 0 0 227 226 1 1
    PRKCB DCAF6 0 0 0 216 1 1
    PRKCB HRAS 0 900 323 931 1 1
    PRKCB CTNNB1 0 0 293 293 1 1
    PRKCB DNM3 0 0 46 158 1 1
    PRKCB IKBKE 0 0 0 162 1 1
    PRKCB CACNA1C 0 600 170 661 1 1
    PRKCB WIPF3 0 0 144 194 1 1
    PRKCB GABRB2 213 0 0 281 1 1
    PRKCB ARAF 0 800 82 807 1 1
    PRKCB CXCR4 0 0 181 233 1 2
    PRKCB RRAS 0 600 124 634 1 1
    PRKCB SULT1A2 0 0 434 434 1 1
    PRKCB TAMM41 117 0 0 150 1 1
    PRKCB MTOR 0 800 376 872 1 2
    PRKCB GABRA1 0 0 112 231 1 1
    PRKCB UBL4B 0 0 0 155 1 1
    PRKCB GNA13 270 0 96 343 1 1
    PRKCB GRM7 0 0 88 155 1 1
    PRKCB TBC1D16 0 0 82 243 1 1
    PRKCB NPHS1 0 0 160 159 1 1
    PRKCB COL27A1 0 0 73 150 1 1
    PRKCB GZMB 0 0 67 188 1 1
    PRKCB KCNMA1 0 0 120 202 1 1
    PRKCB PLEK 0 0 268 384 1 1
    PRKCB OCLN 213 0 212 353 1 1
    PRKCB STAT1 117 0 211 273 1 1
    PRKCB CREBBP 0 0 186 211 1 1
    PRKCB PFKFB3 0 0 0 542 1 1
    PRKCB ARHGAP30 0 0 90 150 1 1
    PRKCB BCL11B 0 0 93 164 1 1
    PRKCB CADPS2 0 0 90 182 1 1
    PRKCB USP9X 0 0 113 243 1 1
    PRKCB GCNT1 213 0 0 222 1 1
    PRKCB CREB1 0 600 252 688 1 1
    PRKCB IL2RB 0 900 82 919 1 1
    PRKCB SH3KBP1 0 0 143 173 1 1
    PRKCB KCNG4 0 0 0 374 1 1
    PRKCB NRG2 0 900 46 900 1 1
    PRKCB AGAP2 0 0 0 258 1 1
    PRKCB GRID2IP 0 0 0 195 1 1
    PRKCB IL4R 0 0 140 174 1 1
    PRKCB TRIP12 0 0 75 243 1 1
    PRKCB ZAP70 0 0 283 248 1 1
    PRKCB ITGA4 0 0 63 233 1 1
    PRKCB CACNA1G 0 0 141 202 1 1
    PRKCB P2RY8 0 0 92 207 1 1
    PRKCB IGF2BP2 0 0 57 313 1 1
    PRKCB RELA 0 900 272 929 1 1
    PRKCB NFKB1 0 0 181 270 1 1
    PRKCB TRPC3 0 800 144 871 1 1
    PRKCB GAPDH 0 0 298 298 1 2
    PRKCB CD22 0 0 244 296 1 1
    PRKCB SYT15 0 0 144 175 1 1
    PRKCB HTR3A 0 0 54 213 1 1
    PRKCB DACT1 0 0 57 181 1 1
    PRKCB MAP2K7 0 0 430 201 1 1
    PRKCB KCNB1 0 0 74 351 1 2
    PRKCB GRHL1 0 0 292 302 1 1
    PRKCB ERG 0 0 74 161 1 1
    PRKCB ENSG00000173366 0 0 181 202 1 1
    PRKCB PARD3B 0 0 0 184 1 1
    PRKCB XYLT1 0 0 0 163 1 1
    PRKCB SLC8A2 0 0 95 180 1 1
    PRKCB KIAA0226L 0 0 134 176 1 1
    PRKCB RGS7 0 0 122 245 1 1
    PRKCB GZMA 0 0 113 181 1 1
    PRKCB MYH7B 0 0 63 240 1 1
    PRKCB ITGAL 0 0 124 276 1 1
    PRKCB KCNN1 0 600 48 650 1 1
    PRKCB UBA6 0 0 112 167 1 1
    PRKCB MAPK8IP2 0 0 60 280 1 1
    PRKCB NRG3 0 900 64 904 1 1
    PRKCB JUN 0 0 395 394 1 1
    PRKCB TMTC2 0 0 67 179 1 1
    PRKCB NOS1 0 900 127 910 1 1
    PRKCB MYO3A 0 0 0 412 1 1
    PRKCB GRHL2 0 0 297 310 1 1
    PRKCB JAK3 0 900 134 909 1 1
    PRKCB HMG20B 0 0 357 373 1 1
    PRKCB ZBTB16 0 0 48 258 1 1
    PRKCB PIK3CG 270 0 534 688 1 1
    PRKCB AIF1 0 0 0 212 1 1
    PRKCB ERBB4 0 900 159 908 1 1
    PRKCB OTOS 0 0 0 188 1 1
    PRKCB IRS2 0 0 242 241 1 1
    PRKCB SORD 0 0 229 228 1 1
    PRKCB GAP43 213 0 112 345 1 1
    PRKCB NRK 0 0 0 212 1 1
    PRKCB LSP1 270 0 51 325 1 1
    PRKCB PUM2 0 0 0 157 1 1
    PRKCB PLCH2 0 0 58 182 1 1
    PRKCB TNFRSF13C 0 0 281 281 1 1
    PRKCB TRPC7 0 0 0 309 1 1
    PRKCB CREB3L2 0 600 0 603 1 1
    PRKCB GRIN2A 0 0 150 242 1 1
    PRKCB FYN 0 0 381 227 1 1
    PRKCB LRRC16A 117 0 54 281 1 1
    PRKCB NFKBIE 0 0 156 172 1 1
    PRKCB GRB2 0 0 286 367 1 1
    PRKCB SPTBN1 0 360 0 470 1 1
    PRKCB SOD1 0 0 112 154 1 1
    PRKCB TBL1X 0 0 62 161 1 1
    PRKCB BSN 0 0 63 174 1 2
    PRKCB TRPC5 0 0 0 309 1 1
    PRKCB IL7R 0 0 114 166 1 1
    PRKCB BCL10 0 650 561 839 1 1
    PRKCB PTPRC 0 0 182 363 1 1
    PRKCB RGS14 0 0 72 201 1 1
    PRKCB GTF3C1 0 0 46 229 1 1
    PRKCB ICAM1 0 0 315 315 1 1
    PRKCB CCNB2 0 0 53 215 1 1
    PRKCB TINF2 295 0 0 295 1 1
    PRKCB GNB1 0 900 145 913 1 1
    PRKCB GNRH1 0 0 118 156 1 1
    PRKCB HIST1H3D 270 0 304 481 1 1
    PRKCB AR 270 0 321 486 1 1
    PRKCB IFNAR2 213 0 44 215 1 1
    PRKCB STX1A 0 0 167 237 1 1
    PRKCB SYN1 0 0 108 176 1 1
    PRKCB STX4 0 900 122 909 1 1
    PRKCB NCKAP5L 0 0 113 211 1 1
    PRKCB GNA12 270 0 57 328 1 1
    PRKCB GNA14 0 0 60 161 1 1
    PRKCB GRAP2 0 0 120 218 1 1
    PRKCB SELL 0 0 54 164 1 1
    PRKCB TTF2 0 800 0 800 1 1
    PRKCB MAPK3 0 900 459 933 1 2
    PRKCB GTF2I 0 0 194 199 1 1
    PRKCB MMP9 0 0 207 207 1 1
    PRKCB GABRD 0 0 96 177 1 1
    PRKCB SQSTM1 0 0 90 218 1 2
    PRKCB SLC16A1 117 0 0 172 1 1
    PRKCB DPP6 0 0 76 163 1 1
    PRKCB HSP90AA1 129 0 218 320 1 2
    PRKCB CTBP1 0 0 56 226 1 1
    PRKCB CREB3L1 0 600 45 604 1 1
    PRKCB SYT1 0 0 166 150 1 1
    PRKCB ATF2 0 600 0 600 1 1
    PRKCB PSEN1 0 0 142 153 1 2
    PRKCB CRP 0 0 152 151 1 1
    PRKCB CCL2 0 0 278 278 1 2
    PRKCB GNB2 0 650 0 676 1 1
    PRKCB PPP2R1B 0 600 0 602 1 1
    PRKCB GABRA4 0 0 87 178 1 1
    PRKCB ALB 0 0 337 352 1 1
    PRKCB IL16 0 0 57 283 1 1
    PRKCB CREB3L3 0 600 0 609 1 1
    PRKCB TRIM41 270 0 418 557 1 1
    PRKCB PITPNM1 0 0 0 160 1 1
    PRKCB RAP1GAP2 0 0 81 165 1 1
    PRKCB TYROBP 0 0 57 197 1 1
    PRKCB SPTBN4 0 360 0 370 1 1
    PRKCB IL4 0 0 202 202 1 1
    PRKCB ELMO1 0 0 151 249 1 1
    PRKCB RAP1B 0 0 131 166 1 1
    PRKCB ADRA2A 0 650 0 663 1 1
    PRKCB NUMB 270 0 0 270 1 1
    PRKCB LEF1 0 0 117 201 1 1
    PRKCB ADIPOR1 0 0 0 252 1 1
    PRKCB PRMT6 0 0 306 316 1 1
    PRKCB EP300 270 0 185 394 1 1
    PRKCB GRHL3 0 0 487 487 1 1
    PRKCB RNF123 270 0 0 270 1 1
    PRKCB ROCK1 0 0 182 183 1 1
    PRKCB DAG1 0 900 0 900 1 1
    PRKCB SMAD3 0 0 156 155 1 1
    PRKCB PHACTR1 0 0 122 195 1 1
    PRKCB BIRC3 0 0 184 184 1 1
    PRKCB ADRA2B 0 650 74 680 1 1
    PRKCB NEFL 0 0 95 156 1 1
    PRKCB AGER 0 0 181 181 1 1
    PRKCB OTOG 0 0 167 185 1 1
    PRKCB KCNIP3 0 0 96 316 1 1
    PRKCB CALML3 0 0 167 167 1 1
    PRKCB NRG4 0 900 43 900 1 1
    PRKCB NCF4 0 900 166 920 1 1
    PRKCB PRKCZ 0 900 416 910 1 1
    PRKCB ADAP1 0 0 0 168 1 1
    PRKCB ZNF365 0 0 90 231 1 1
    PRKCB DRD2 270 0 103 327 1 1
    PRKCB PPP1CB 0 0 159 224 1 1
    PRKCB ALK 0 0 285 193 1 1
    PRKCB CPXM2 0 0 0 158 1 1
    PRKCB KLHL6 0 0 107 181 1 1
    PRKCB HSDL2 117 0 88 230 1 1
    PRKCB GRM3 0 0 113 228 1 1
    PRKCB VR1 0 0 454 463 1 1
    PRKCB BLVRA 270 0 74 295 1 1
    PRKCB FAM136A 0 0 372 372 1 1
    PRKCB CCR1 0 0 83 152 1 1
    PRKCB PPP2CB 213 600 0 698 1 1
    PRKCB MAPK8 0 900 325 919 1 2
    PRKCB PTK2 0 800 193 814 1 1
    PRKCB RNF17 0 0 58 190 1 1
    PRKCB GABBR2 0 0 103 179 1 1
    PRKCB ITGA7 0 0 61 172 1 1
    PRKCB PLD1 0 900 107 906 1 1
    PRKCB PRKAR1B 0 0 107 366 1 1
    PRKCB BRAF 0 900 108 909 1 1
    PRKCB GADD45B 0 0 150 181 1 1
    PRKCB CSNK1A1L 0 0 123 163 1 1
    PRKCB DGKZ 0 0 156 259 1 1
    PRKCB SCTR 0 0 0 252 1 1
    PRKCB CYCS 0 0 283 282 1 1
    PRKCB DUSP12 0 0 150 188 1 1
    PRKCB GFI1B 0 0 306 306 1 1
    PRKCB TRAF6 0 0 280 358 1 2
    PRKCB SREK1 0 0 71 249 1 1
    PRKCB CDH22 0 0 113 220 1 1
    PRKCB TIAM2 0 0 0 208 1 1
    PRKCB ADD2 0 0 44 219 1 1
    PRKCB RASAL3 0 0 0 271 1 1
    PRKCB EGF 0 900 243 921 1 1
    PRKCB PAWR 0 0 0 150 1 1
    PRKCB GNAZ 0 600 52 638 1 1
    PRKCB PIK3R1 0 0 334 379 1 1
    PRKCB CRHR1 0 0 112 174 1 1
    PRKCB LPIN3 0 650 0 674 1 1
    PRKCB HSPA4 270 0 134 410 1 1
    PRKCB PDZD2 0 0 0 248 1 1
    PRKCB LPL 0 0 137 158 1 1
    PRKCB IER3 0 0 122 156 1 1
    PRKCB TAT 0 0 0 312 1 1
    PRKCB PPARA 0 0 220 220 1 1
    PRKCB VAMP1 0 0 87 162 1 1
    PRKCB CCR2 0 0 102 220 1 2
    PRKCB CHAT 213 0 45 216 1 1
    PRKCB CSDE1 0 0 52 198 1 1
    PRKCB TRPC6 0 0 75 333 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005524 Molecular Function ATP binding enables IEA
    GO:0005246 Molecular Function calcium channel regulator activity enables IEA
    GO:0004698 Molecular Function calcium,diacylglycerol-dependent serine/threonine kinase activity enables IDA
    GO:0003682 Molecular Function chromatin binding enables IDA
    GO:0004697 Molecular Function diacylglycerol-dependent serine/threonine kinase activity enables EXP
    GO:0004697 Molecular Function diacylglycerol-dependent serine/threonine kinase activity enables TAS
    GO:0004699 Molecular Function diacylglycerol-dependent, calcium-independent serine/threonine kinase activity enables IEA
    GO:0035403 Molecular Function histone H3T6 kinase activity enables IDA
    GO:0042393 Molecular Function histone binding enables IDA
    GO:0050681 Molecular Function nuclear androgen receptor binding enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0005080 Molecular Function protein kinase C binding enables IPI
    GO:0106310 Molecular Function protein serine kinase activity enables IEA
    GO:0004674 Molecular Function protein serine/threonine kinase activity enables IBA
    GO:0004674 Molecular Function protein serine/threonine kinase activity enables TAS
    GO:0003713 Molecular Function transcription coactivator activity enables IMP
    GO:0008270 Molecular Function zinc ion binding enables IEA
    GO:0042113 Biological Process B cell activation involved_in ISS
    GO:0050853 Biological Process B cell receptor signaling pathway involved_in ISS
    GO:0002250 Biological Process adaptive immune response involved_in IEA
    GO:0006915 Biological Process apoptotic process involved_in IEA
    GO:0006816 Biological Process calcium ion transport involved_in IEA
    GO:0071322 Biological Process cellular response to carbohydrate stimulus involved_in IEA
    GO:0006338 Biological Process chromatin remodeling involved_in IEA
    GO:0018894 Biological Process dibenzo-p-dioxin metabolic process involved_in IEA
    GO:0006874 Biological Process intracellular calcium ion homeostasis involved_in IEA
    GO:0035556 Biological Process intracellular signal transduction involved_in IBA
    GO:0042953 Biological Process lipoprotein transport involved_in TAS
    GO:0007077 Biological Process mitotic nuclear membrane disassembly involved_in TAS
    GO:0010829 Biological Process negative regulation of D-glucose transmembrane transport involved_in ISS
    GO:0046627 Biological Process negative regulation of insulin receptor signaling pathway involved_in ISS
    GO:0007207 Biological Process phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway involved_in IEA
    GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IEA
    GO:0045766 Biological Process positive regulation of angiogenesis involved_in ISS
    GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in ISS
    GO:0032024 Biological Process positive regulation of insulin secretion involved_in IEA
    GO:0042488 Biological Process positive regulation of odontogenesis of dentin-containing tooth involved_in IEA
    GO:0030949 Biological Process positive regulation of vascular endothelial growth factor receptor signaling pathway involved_in ISS
    GO:0099171 Biological Process presynaptic modulation of chemical synaptic transmission involved_in IEA
    GO:0070528 Biological Process protein kinase C signaling involved_in IDA
    GO:0006468 Biological Process protein phosphorylation involved_in TAS
    GO:0010827 Biological Process regulation of D-glucose transmembrane transport involved_in IDA
    GO:0014059 Biological Process regulation of dopamine secretion involved_in IEA
    GO:0040008 Biological Process regulation of growth involved_in IEA
    GO:2000300 Biological Process regulation of synaptic vesicle exocytosis involved_in IEA
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IMP
    GO:1990776 Biological Process response to angiotensin involved_in IEA
    GO:0045471 Biological Process response to ethanol involved_in IEA
    GO:0009749 Biological Process response to glucose involved_in IEA
    GO:0033280 Biological Process response to vitamin D involved_in IEA
    GO:0009410 Biological Process response to xenobiotic stimulus involved_in IEA
    GO:0007165 Biological Process signal transduction involved_in NAS
    GO:0031526 Cellular Component brush border membrane located_in IEA
    GO:0044305 Cellular Component calyx of Held located_in IEA
    GO:0005813 Cellular Component centrosome located_in IEA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in TAS
    GO:0099523 Cellular Component presynaptic cytosol located_in IEA
    GO:0008091 Cellular Component spectrin part_of IEA
    Pathways
    Name DB ID
    Hemostasis Reactome R-HSA-109582
    Neurotransmitter receptors and postsynaptic signal transmission Reactome R-HSA-112314
    Transmission across Chemical Synapses Reactome R-HSA-112315
    Neuronal System Reactome R-HSA-112316
    Disinhibition of SNARE formation Reactome R-HSA-114516
    Downstream signaling events of B Cell Receptor (BCR) Reactome R-HSA-1168372
    Activation of NF-kappaB in B cells Reactome R-HSA-1169091
    Adaptive Immune System Reactome R-HSA-1280218
    Signal Transduction Reactome R-HSA-162582
    Cell Cycle Reactome R-HSA-1640170
    Immune System Reactome R-HSA-168256
    Signaling by VEGF Reactome R-HSA-194138
    Signaling by Rho GTPases Reactome R-HSA-194315
    RHO GTPase Effectors Reactome R-HSA-195258
    Signaling by WNT Reactome R-HSA-195721
    Generic Transcription Pathway Reactome R-HSA-212436
    Nuclear Envelope Breakdown Reactome R-HSA-2980766
    Signaling by GPCR Reactome R-HSA-372790
    Beta-catenin independent WNT signaling Reactome R-HSA-3858494
    GPCR downstream signalling Reactome R-HSA-388396
    Trafficking of AMPA receptors Reactome R-HSA-399719
    Glutamate binding, activation of AMPA receptors and synaptic plasticity Reactome R-HSA-399721
    PCP/CE pathway Reactome R-HSA-4086400
    Trafficking of GluR2-containing AMPA receptors Reactome R-HSA-416993
    G alpha (z) signalling events Reactome R-HSA-418597
    Depolymerization of the Nuclear Lamina Reactome R-HSA-4419969
    VEGFA-VEGFR2 Pathway Reactome R-HSA-4420097
    WNT5A-dependent internalization of FZD4 Reactome R-HSA-5099900
    VEGFR2 mediated cell proliferation Reactome R-HSA-5218921
    RHO GTPases Activate NADPH Oxidases Reactome R-HSA-5668599
    Mitotic Prophase Reactome R-HSA-68875
    M Phase Reactome R-HSA-68886
    Cell Cycle, Mitotic Reactome R-HSA-69278
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Gene expression (Transcription) Reactome R-HSA-74160
    Platelet activation, signaling and aggregation Reactome R-HSA-76002
    Response to elevated platelet cytosolic Ca2+ Reactome R-HSA-76005
    Transcriptional regulation by RUNX1 Reactome R-HSA-8878171
    RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Reactome R-HSA-8939246
    Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
    Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Reactome R-HSA-9716542
    Signaling by the B Cell Receptor (BCR) Reactome R-HSA-983705
    Kisspeptin/kisspeptin receptor system in the ovary (WP4871) WikiPathways WP4871_r120412
    Focal adhesion (WP306) WikiPathways WP306_r116784
    Neuroinflammation and glutamatergic signaling (WP5083) WikiPathways WP5083_r120385
    Sphingolipid metabolism in senescence (WP5121) WikiPathways WP5121_r119472
    Wnt signaling (WP428) WikiPathways WP428_r116549
    Serotonin and anxiety-related events (WP3944) WikiPathways WP3944_r120596
    G protein signaling pathways (WP35) WikiPathways WP35_r117729
    Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
    Oncostatin M signaling pathway (WP2374) WikiPathways WP2374_r120781
    PDGFR-beta pathway (WP3972) WikiPathways WP3972_r108157
    GPR143 in melanocytes and retinal pigment epithelium cells (WP4941) WikiPathways WP4941_r120578
    Myometrial relaxation and contraction pathways (WP289) WikiPathways WP289_r122789
    EGFR tyrosine kinase inhibitor resistance (WP4806) WikiPathways WP4806_r123492
    Ras signaling (WP4223) WikiPathways WP4223_r119284
    Wnt signaling pathway and pluripotency (WP399) WikiPathways WP399_r119242
    ErbB signaling pathway (WP673) WikiPathways WP673_r118930
    Common pathways underlying drug addiction (WP2636) WikiPathways WP2636_r116781
    Hippo signaling regulation pathways (WP4540) WikiPathways WP4540_r120395
    Chronic hyperglycemia impairment of neuron function (WP5283) WikiPathways WP5283_r124551
    Glioblastoma signaling pathways (WP2261) WikiPathways WP2261_r123065
    Physiological and pathological hypertrophy of the heart (WP1528) WikiPathways WP1528_r121714
    Osteoblast differentiation and related diseases (WP4787) WikiPathways WP4787_r118872
    MicroRNAs in cardiomyocyte hypertrophy (WP1544) WikiPathways WP1544_r121713
    Corticotropin-releasing hormone signaling pathway (WP2355) WikiPathways WP2355_r120664
    Chemokine signaling pathway (WP3929) WikiPathways WP3929_r119247
    IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
    Wnt signaling pathway (WP363) WikiPathways WP363_r120695
    Regulatory circuits of the STAT3 signaling pathway (WP4538) WikiPathways WP4538_r104390
    Insulin signaling (WP481) WikiPathways WP481_r120562
    B cell receptor signaling pathway (WP23) WikiPathways WP23_r120701
    EGF/EGFR signaling pathway (WP437) WikiPathways WP437_r120689
    Calcium regulation in cardiac cells (WP536) WikiPathways WP536_r116854
    Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
    AGE/RAGE pathway (WP2324) WikiPathways WP2324_r120674
    Kit receptor signaling pathway (WP304) WikiPathways WP304_r120696
    Non-genomic actions of 1,25 dihydroxyvitamin D3 (WP4341) WikiPathways WP4341_r122900
    Serotonin and anxiety (WP3947) WikiPathways WP3947_r106483
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_002738 7 mRNA transcript variant 2 NC_000016 Reference
    NM_212535 3 mRNA transcript variant 1 NC_000016 Reference
    XM_047434365 1 mRNA transcript variant X1 NC_000016 Reference