PRKAB1

protein kinase AMP-activated non-catalytic subunit beta 1
General Information
Name protein kinase AMP-activated non-catalytic subunit beta 1
Alias
  • 5'-AMP-activated protein kinase subunit beta-1
  • 5'-AMP-activated protein kinase beta-1 subunit
  • AMP-activated protein kinase beta subunit
  • AMPK beta -1 chain
  • AMPK beta 1
  • AMPK subunit beta-1
  • AMPKb
  • protein kinase, AMP-activated, beta 1 non-catalytic subunit
  • protein kinase, AMP-activated, noncatalytic, beta-1
Synonyms AMPK HAMPKb
Gene_family None
organism Homo sapiens
entrez_id 5564
location 12q24.23
transcript_count 2
exon_count 8
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
      Stringdb 5'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...]
      nextProt Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    PRKAB1 BioGRID MTCL2 GeneID BioGRID Affinity Capture-Western
    PRKAB1 BioGRID SLC31A1 GeneID BioGRID Biochemical Activity
    PRKAB1 BioGRID PRKAA2 GeneID BioGRID Affinity Capture-MS; Co-fractionation; Two-hybrid
    PRKAB1 BioGRID PRKAA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
    PRKAB1 BioGRID SPPL3 GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PRKAG3 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    PRKAB1 BioGRID PRKAG2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    PRKAB1 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID LAMTOR2 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID ATP6V0D1 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID ATP6V1B2 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID ATP6V1A GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID N GeneID BioGRID Protein-RNA
    PRKAB1 BioGRID MINK1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID RFESD GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ATXN7L1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID TRMT44 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID TRIM11 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID TUBB1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID DCLRE1C GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    PRKAB1 BioGRID HEATR6 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID MID1IP1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID STIM2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID LAMTOR1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    PRKAB1 BioGRID POLR3K GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CUTA GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PLA2G2D GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SCRIB GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID HARS2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CAMKK2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID AP5Z1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID NEK4 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SLC9A5 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PLAAT4 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PRKAG1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    PRKAB1 BioGRID PRKAB2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PHKG2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PEX1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID MCL1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CCKBR GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
    PRKAB1 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    PRKAB1 BioGRID ZFHX3 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CFAP91 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SPRING1 GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID GAL3ST2 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID UBE2O GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ALX4 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PARS2 GeneID BioGRID Affinity Capture-Western
    PRKAB1 BioGRID CEP68 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ENTR1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    PRKAB1 BioGRID PEMT GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SOCS5 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PHOX2B GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SREBF2 GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID MFAP3 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID VWA5A GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID DCT GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ACR GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID MDP1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID PTP4A1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID DCXR GeneID BioGRID Negative Genetic
    PRKAB1 BioGRID CIT GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID MST1R GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID JAK3 GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID AKT2 GeneID BioGRID Positive Genetic
    PRKAB1 BioGRID TUBA4A GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ULK1 GeneID BioGRID Affinity Capture-Western
    PRKAB1 BioGRID Prkaa1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID AP1M1 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID PFDN2 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID FKBP4 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID AP1G1 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID AP1B1 GeneID BioGRID Co-fractionation
    PRKAB1 BioGRID MAST3 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SNF4 GeneID BioGRID Two-hybrid
    PRKAB1 BioGRID SNF1 GeneID BioGRID Two-hybrid
    PRKAB1 BioGRID CIDEA GeneID BioGRID Affinity Capture-Western
    PRKAB1 BioGRID ACACA GeneID BioGRID Biochemical Activity
    PRKAB1 BioGRID APP GeneID BioGRID Reconstituted Complex
    PRKAB1 BioGRID MAP3K7 GeneID BioGRID Biochemical Activity
    PRKAB1 BioGRID MAPK6 GeneID BioGRID Two-hybrid
    PRKAB1 BioGRID GRB2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PRKAB1 BioGRID HDAC5 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    PRKAB1 BioGRID NSF GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID DSC1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CBR1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID CASP14 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID TGM3 GeneID BioGRID Affinity Capture-MS
    PRKAB1 Protein NDUFA7 GeneID HPRD None
    PRKAB1 Protein PRKAG2 GeneID HPRD None
    PRKAB1 Protein PRKAG1 GeneID HPRD None
    PRKAB1 Protein PRKAA1 GeneID HPRD None
    PRKAB1 Protein PRKAA2 GeneID HPRD None
    PRKAB1 Protein AGL GeneID HPRD None
    PRKAB1 Protein F10 GeneID HPRD None
    PRKAB1 BioGRID FNIP1 GeneID BioGRID Affinity Capture-Western
    PRKAB1 BioGRID F10 GeneID BioGRID Two-hybrid
    PRKAB1 BioGRID NDUFA7 GeneID BioGRID Two-hybrid
    PRKAB1 BioGRID DHX36 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID SNRNP200 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID EZR GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID MYH10 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID MARS1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID GYS1 GeneID BioGRID Affinity Capture-MS
    PRKAB1 BioGRID ACLY GeneID BioGRID Affinity Capture-MS
    StringDB
    A B experiments database textmining combined score hadb nhadb
    PRKAB1 AZI2 0 0 134 176 1 1
    PRKAB1 IGF1R 0 0 108 206 1 1
    PRKAB1 HMGCLL1 0 0 155 207 1 1
    PRKAB1 MYC 0 0 194 194 1 2
    PRKAB1 CHMP4C 0 0 179 179 1 1
    PRKAB1 PPIP5K1 0 0 0 185 1 1
    PRKAB1 PIK3CA 0 0 74 237 1 2
    PRKAB1 NAPSA 0 0 0 236 1 1
    PRKAB1 ACACA 270 900 390 954 1 1
    PRKAB1 USP10 0 0 160 180 1 2
    PRKAB1 CTDSP1 0 0 0 212 1 1
    PRKAB1 PPP3CB 0 0 0 191 1 1
    PRKAB1 ACSL1 0 0 74 172 1 1
    PRKAB1 COX7A2 0 0 0 332 1 1
    PRKAB1 PPP3CC 0 0 0 191 1 1
    PRKAB1 HDAC5 270 0 82 319 1 1
    PRKAB1 SH3BGRL 0 0 0 286 1 1
    PRKAB1 PFKM 0 0 125 156 1 1
    PRKAB1 C12orf10 0 0 0 163 1 1
    PRKAB1 MAP2K1 0 0 108 180 1 1
    PRKAB1 MFF 0 0 166 189 1 1
    PRKAB1 CAB39 0 900 413 946 1 1
    PRKAB1 ENSG00000272772 0 0 0 233 1 1
    PRKAB1 CIDEA 270 0 122 397 1 1
    PRKAB1 AKT2 105 0 89 300 1 1
    PRKAB1 EME1 0 0 0 158 1 1
    PRKAB1 CDK4 0 0 96 181 1 1
    PRKAB1 PRKCI 0 0 57 171 1 1
    PRKAB1 UBIAD1 0 0 0 152 1 1
    PRKAB1 PRKCE 0 0 0 167 1 1
    PRKAB1 CFTR 0 800 0 819 1 1
    PRKAB1 CHPT1 0 0 0 162 1 1
    PRKAB1 SNAP23 0 0 44 164 1 1
    PRKAB1 BRSK1 0 0 181 285 1 1
    PRKAB1 HK2 0 0 154 303 1 1
    PRKAB1 MRPL43 0 0 150 343 1 1
    PRKAB1 BMP2K 0 0 0 153 1 1
    PRKAB1 CAMKK2 0 900 519 975 1 2
    PRKAB1 TPR 0 0 0 179 1 1
    PRKAB1 SKIV2L 0 0 0 183 1 1
    PRKAB1 VDAC2 0 0 48 189 1 1
    PRKAB1 CPT2 0 0 243 315 1 1
    PRKAB1 PPP1R12C 0 0 123 192 1 1
    PRKAB1 EFCAB2 0 0 48 197 1 1
    PRKAB1 ERN1 0 0 90 191 1 2
    PRKAB1 LAMTOR4 0 900 0 911 1 1
    PRKAB1 SLC22A3 0 0 181 204 1 1
    PRKAB1 DYNLL1 0 900 57 903 1 1
    PRKAB1 GLRX5 0 0 0 155 1 1
    PRKAB1 MAPK13 0 0 52 152 1 1
    PRKAB1 MTMR6 0 0 0 161 1 1
    PRKAB1 UBE2R2 0 0 0 155 1 1
    PRKAB1 CLN3 0 0 57 160 1 2
    PRKAB1 HIF1A 0 0 241 320 1 2
    PRKAB1 PYGL 0 0 102 225 1 1
    PRKAB1 SIRT5 0 0 48 204 1 1
    PRKAB1 GCK 0 0 61 226 1 1
    PRKAB1 PSMC2 0 0 0 154 1 1
    PRKAB1 PLA2G4A 0 0 134 278 1 1
    PRKAB1 ACSL3 0 0 53 173 1 1
    PRKAB1 PRKAG1 978 900 901 999 1 1
    PRKAB1 SH2B2 0 0 123 190 1 1
    PRKAB1 LIPE 0 800 86 809 1 1
    PRKAB1 DNAH10 0 0 120 159 1 1
    PRKAB1 AP1B1 680 0 0 697 1 1
    PRKAB1 SMARCAD1 0 0 0 179 1 1
    PRKAB1 KAT7 0 0 0 150 1 1
    PRKAB1 SDE2 0 0 0 155 1 1
    PRKAB1 HEATR5A 0 0 0 182 1 1
    PRKAB1 PRMT1 0 0 0 151 1 1
    PRKAB1 SCO2 0 0 241 250 1 1
    PRKAB1 CCNC 0 0 0 287 1 1
    PRKAB1 MAST1 0 0 0 248 1 1
    PRKAB1 SBK1 0 0 44 159 1 1
    PRKAB1 LGR4 0 0 0 161 1 1
    PRKAB1 RPS6 0 0 195 372 1 1
    PRKAB1 MYSM1 0 0 74 383 1 1
    PRKAB1 TUBB1 131 0 0 150 1 1
    PRKAB1 ASCL5 0 0 216 216 1 1
    PRKAB1 PLCG2 0 0 0 161 1 1
    PRKAB1 MBOAT7 0 0 0 194 1 1
    PRKAB1 PIN4 0 0 113 227 1 1
    PRKAB1 LONP1 0 0 66 165 1 1
    PRKAB1 KCNJ11 0 0 90 375 1 1
    PRKAB1 PDXK 62 0 74 174 1 1
    PRKAB1 PRKACA 0 540 0 581 1 1
    PRKAB1 PLGRKT 0 0 0 156 1 1
    PRKAB1 PFKL 0 0 52 152 1 1
    PRKAB1 CTDSPL2 0 0 0 212 1 1
    PRKAB1 SLC2A10 0 0 0 191 1 1
    PRKAB1 DTNA 0 0 73 326 1 1
    PRKAB1 PLEC 0 0 66 170 1 1
    PRKAB1 IST1 0 0 0 183 1 1
    PRKAB1 NPPA 0 0 0 299 1 1
    PRKAB1 AK3 0 0 0 187 1 1
    PRKAB1 TSTD1 0 0 0 280 1 1
    PRKAB1 BCL2L1 0 0 96 267 1 2
    PRKAB1 PIK3R4 0 900 94 907 1 2
    PRKAB1 LONRF2 0 0 0 159 1 1
    PRKAB1 GPS1 0 0 89 280 1 1
    PRKAB1 GABARAPL2 0 0 66 155 1 2
    PRKAB1 BRSK2 0 0 210 311 1 1
    PRKAB1 LMOD1 0 0 0 191 1 1
    PRKAB1 APTX 0 0 0 152 1 1
    PRKAB1 KSR2 0 0 150 228 1 1
    PRKAB1 SLC25A11 0 0 0 171 1 1
    PRKAB1 ATG14 0 900 141 910 1 2
    PRKAB1 HEPH 0 0 0 164 1 1
    PRKAB1 MYL7 0 0 0 155 1 1
    PRKAB1 SLC45A1 0 0 0 192 1 1
    PRKAB1 TSC1 0 900 188 915 1 2
    PRKAB1 PACRGL 0 0 0 161 1 1
    PRKAB1 PFDN2 272 0 0 272 1 1
    PRKAB1 NRF1 0 0 123 158 1 1
    PRKAB1 OGDH 0 0 67 179 1 1
    PRKAB1 ULK2 273 0 321 521 1 2
    PRKAB1 ENSG00000268434 0 0 0 304 1 1
    PRKAB1 CHEK1 0 0 73 204 1 1
    PRKAB1 SNAP29 0 0 113 477 1 2
    PRKAB1 AKT1S1 0 600 147 652 1 1
    PRKAB1 VSNL1 0 0 0 162 1 1
    PRKAB1 LIMK2 0 0 61 252 1 1
    PRKAB1 TFAM 0 0 123 156 1 1
    PRKAB1 NEK3 0 0 112 309 1 1
    PRKAB1 IGFBP3 0 0 211 211 1 1
    PRKAB1 WDFY1 0 0 0 173 1 1
    PRKAB1 PEMT 128 0 0 242 1 1
    PRKAB1 BAIAP2L1 0 0 92 204 1 1
    PRKAB1 UBE2F 0 0 0 171 1 1
    PRKAB1 RSPH6A 0 0 154 190 1 1
    PRKAB1 XPC 0 0 0 179 1 1
    PRKAB1 YWHAE 0 0 0 175 1 1
    PRKAB1 LAMP2 0 0 140 156 1 2
    PRKAB1 GABARAPL1 0 0 71 160 1 2
    PRKAB1 MPC1 0 0 0 173 1 1
    PRKAB1 SIRT7 0 0 55 168 1 1
    PRKAB1 NIM1K 0 0 0 452 1 1
    PRKAB1 RAB1A 0 0 60 351 1 2
    PRKAB1 NSFL1C 0 0 0 155 1 1
    PRKAB1 PGAM2 0 0 154 183 1 1
    PRKAB1 GNG7 0 600 0 600 1 1
    PRKAB1 INSR 0 0 95 195 1 1
    PRKAB1 HSPA8 0 900 112 910 1 2
    PRKAB1 CRTC2 0 800 211 835 1 1
    PRKAB1 CPEB4 0 0 0 171 1 1
    PRKAB1 ZCCHC2 0 0 0 181 1 1
    PRKAB1 MPND 0 0 0 170 1 1
    PRKAB1 SIRT3 0 0 109 289 1 2
    PRKAB1 ENO3 0 0 0 157 1 1
    PRKAB1 BRCC3 0 0 0 175 1 1
    PRKAB1 CIT 105 0 0 187 1 1
    PRKAB1 INS 0 0 373 373 1 1
    PRKAB1 ACTB 0 0 268 277 1 1
    PRKAB1 COX4I1 0 0 96 252 1 1
    PRKAB1 LOC728763 0 0 0 152 1 1
    PRKAB1 LEKR1 0 0 0 177 1 1
    PRKAB1 BACE2 0 0 0 220 1 1
    PRKAB1 HPGDS 0 0 312 312 1 1
    PRKAB1 HEATR5B 0 0 0 182 1 1
    PRKAB1 PNPLA2 0 0 166 180 1 1
    PRKAB1 GNG2 0 600 0 600 1 1
    PRKAB1 BCL9 0 0 0 302 1 1
    PRKAB1 DCAF7 0 0 0 182 1 1
    PRKAB1 VPS8 0 0 0 159 1 1
    PRKAB1 GNB5 0 600 0 662 1 1
    PRKAB1 TTC37 0 0 0 171 1 1
    PRKAB1 LEPR 0 900 95 906 1 1
    PRKAB1 MTG1 0 0 0 151 1 1
    PRKAB1 SDHA 0 0 0 260 1 1
    PRKAB1 SEC63 0 0 0 161 1 1
    PRKAB1 PLCL2 0 0 0 158 1 1
    PRKAB1 CHRAC1 0 0 0 163 1 1
    PRKAB1 PPEF1 0 0 0 191 1 1
    PRKAB1 OSGIN1 0 0 90 152 1 1
    PRKAB1 MLXIPL 0 900 202 919 1 1
    PRKAB1 YWHAG 0 0 50 196 1 1
    PRKAB1 CP 0 0 0 164 1 1
    PRKAB1 HMGCS2 0 0 151 150 1 1
    PRKAB1 SMG5 0 0 0 155 1 1
    PRKAB1 C4BPB 0 0 91 166 1 1
    PRKAB1 DNM2 45 0 0 154 1 1
    PRKAB1 SLC3A2 0 0 0 211 1 1
    PRKAB1 FANCM 0 0 0 161 1 1
    PRKAB1 FKBP1A 0 0 95 174 1 2
    PRKAB1 MT-ND6 0 0 72 152 1 1
    PRKAB1 STIM2 635 0 0 635 1 1
    PRKAB1 ADIPOQ 0 0 260 273 1 1
    PRKAB1 PYGM 0 0 72 197 1 1
    PRKAB1 ZDHHC8 0 0 86 223 1 1
    PRKAB1 PRKAB2 784 900 856 978 1 1
    PRKAB1 FASN 0 0 265 265 1 1
    PRKAB1 HK1 0 0 0 237 1 1
    PRKAB1 PLK2 0 0 144 165 1 1
    PRKAB1 CHEK2 0 0 95 151 1 1
    PRKAB1 RPS6KA3 0 0 123 154 1 1
    PRKAB1 RPTOR 0 900 467 953 1 2
    PRKAB1 ENTPD5 0 0 113 168 1 1
    PRKAB1 TRIB1 0 0 54 459 1 1
    PRKAB1 ZDHHC1 0 0 150 244 1 1
    PRKAB1 NFYC 0 0 0 178 1 1
    PRKAB1 FBXO18 0 0 0 178 1 1
    PRKAB1 DCT 217 0 46 221 1 1
    PRKAB1 FNIP2 270 0 648 732 1 1
    PRKAB1 EEF2 0 0 112 155 1 1
    PRKAB1 MLYCD 0 800 125 818 1 1
    PRKAB1 MYO18B 0 0 185 253 1 1
    PRKAB1 SLC3A1 0 0 42 212 1 1
    PRKAB1 GCG 0 0 163 163 1 1
    PRKAB1 THAP7 0 0 142 600 1 1
    PRKAB1 CDK13 0 0 0 203 1 1
    PRKAB1 LAMC1 0 0 0 155 1 1
    PRKAB1 RPS6KA2 0 0 122 155 1 1
    PRKAB1 MAP3K14 0 0 123 320 1 1
    PRKAB1 LAMTOR2 0 900 0 923 1 1
    PRKAB1 RUFY4 0 0 66 185 1 2
    PRKAB1 DRAM1 0 0 414 414 1 2
    PRKAB1 SLC35D1 0 0 0 303 1 1
    PRKAB1 RAB7A 43 0 0 209 1 2
    PRKAB1 ATF3 0 0 94 228 1 1
    PRKAB1 G3BP1 0 0 113 229 1 1
    PRKAB1 RAB1B 0 0 0 152 1 2
    PRKAB1 PFKFB4 0 600 95 671 1 1
    PRKAB1 CHID1 0 0 0 183 1 1
    PRKAB1 ACSBG2 0 0 0 154 1 1
    PRKAB1 UVRAG 0 0 113 208 1 2
    PRKAB1 GAMT 0 0 126 259 1 1
    PRKAB1 DAGLB 0 0 0 154 1 1
    PRKAB1 PGC 0 0 0 229 1 1
    PRKAB1 RPS6KB1 0 0 328 388 1 2
    PRKAB1 HOXC6 0 0 122 162 1 1
    PRKAB1 PRMT8 0 0 0 151 1 1
    PRKAB1 IRS1 0 0 216 216 1 1
    PRKAB1 SESN1 0 600 558 824 1 2
    PRKAB1 ALG12 0 0 0 160 1 1
    PRKAB1 HK3 0 0 0 209 1 1
    PRKAB1 C14orf2 0 0 0 173 1 1
    PRKAB1 SREBF2 68 0 205 286 1 1
    PRKAB1 CD97 0 0 56 153 1 1
    PRKAB1 SLC27A1 0 0 134 152 1 1
    PRKAB1 BCL2 0 0 44 433 1 2
    PRKAB1 RNASEL 0 0 0 191 1 1
    PRKAB1 ECHDC1 0 0 103 165 1 1
    PRKAB1 ITSN1 0 0 0 266 1 1
    PRKAB1 DDIT4 0 0 261 261 1 1
    PRKAB1 FADS2 0 0 102 176 1 1
    PRKAB1 CDIPT 0 0 0 159 1 1
    PRKAB1 PDPK1 0 0 171 260 1 2
    PRKAB1 KLC2 0 0 150 395 1 1
    PRKAB1 PLCH1 0 0 0 164 1 1
    PRKAB1 LRRK1 0 0 0 173 1 1
    PRKAB1 MCTS1 0 0 0 164 1 1
    PRKAB1 RRAGA 0 900 0 907 1 2
    PRKAB1 H6PD 0 0 0 198 1 1
    PRKAB1 RCCD1 0 0 164 218 1 1
    PRKAB1 ECI2 0 0 91 239 1 1
    PRKAB1 HACE1 0 0 0 160 1 1
    PRKAB1 ATP5C1 0 0 71 233 1 1
    PRKAB1 TSC2 0 900 519 969 1 2
    PRKAB1 PPM1D 0 0 108 202 1 1
    PRKAB1 DHCR24 0 0 62 224 1 1
    PRKAB1 HINT3 0 0 0 327 1 1
    PRKAB1 ABCC12 0 0 0 156 1 1
    PRKAB1 HID1 0 0 0 200 1 1
    PRKAB1 YWHAB 0 0 46 186 1 1
    PRKAB1 CHDH 0 0 61 191 1 1
    PRKAB1 SLK 0 0 539 539 1 1
    PRKAB1 G2E3 0 0 0 169 1 1
    PRKAB1 STAMBP 0 0 0 251 1 1
    PRKAB1 SRC 0 0 81 166 1 1
    PRKAB1 CIB1 0 0 0 156 1 1
    PRKAB1 ACLY 0 0 266 266 1 1
    PRKAB1 SLC2A8 0 0 0 191 1 1
    PRKAB1 SIRT4 0 0 48 237 1 1
    PRKAB1 GSK3A 0 0 53 205 1 1
    PRKAB1 NDUFB6 0 0 74 163 1 1
    PRKAB1 RAB21 0 0 0 256 1 1
    PRKAB1 USH2A 0 0 0 152 1 1
    PRKAB1 OR4L1 0 0 112 152 1 1
    PRKAB1 GYS2 0 600 194 688 1 1
    PRKAB1 PRDX3 0 0 43 203 1 1
    PRKAB1 ENSG00000274276 0 0 123 241 1 1
    PRKAB1 UBLCP1 0 0 0 213 1 1
    PRKAB1 PPARG 0 0 288 333 1 1
    PRKAB1 TMED2 0 0 0 214 1 1
    PRKAB1 AKT1 0 0 405 470 1 2
    PRKAB1 NDUFAF3 0 0 0 256 1 1
    PRKAB1 PRDM16 0 0 128 150 1 1
    PRKAB1 SGK3 0 0 0 213 1 1
    PRKAB1 IKBKB 0 0 86 170 1 1
    PRKAB1 LGR6 0 0 0 187 1 1
    PRKAB1 PPP2R4 0 0 193 326 1 1
    PRKAB1 PHKG2 479 0 0 480 1 1
    PRKAB1 CTDNEP1 0 0 0 218 1 1
    PRKAB1 LPIN1 0 0 91 153 1 2
    PRKAB1 KRT76 0 0 141 194 1 1
    PRKAB1 SYNRG 0 0 0 181 1 1
    PRKAB1 ESYT3 0 0 0 159 1 1
    PRKAB1 PFKFB1 0 600 103 700 1 1
    PRKAB1 SLC45A2 0 0 0 192 1 1
    PRKAB1 MAPK11 0 0 0 158 1 1
    PRKAB1 PPM1A 0 900 134 925 1 1
    PRKAB1 NUAK2 0 0 270 299 1 1
    PRKAB1 CAB39L 0 900 180 924 1 1
    PRKAB1 MAPT 0 900 0 900 1 2
    PRKAB1 BECN1 0 900 242 930 1 2
    PRKAB1 AP1S1 0 0 0 152 1 1
    PRKAB1 COX4I2 0 0 0 151 1 1
    PRKAB1 ABCC1 0 0 0 163 1 1
    PRKAB1 GYS1 62 600 321 746 1 1
    PRKAB1 ACADSB 0 0 167 180 1 1
    PRKAB1 PKN2 0 0 0 180 1 1
    PRKAB1 TSSK4 0 0 0 452 1 1
    PRKAB1 PGM2 0 0 0 227 1 1
    PRKAB1 GNB3 0 600 0 662 1 1
    PRKAB1 MLST8 0 900 150 922 1 2
    PRKAB1 SLC2A9 0 0 181 193 1 1
    PRKAB1 PGA4 0 0 0 220 1 1
    PRKAB1 RXRA 0 0 0 161 1 1
    PRKAB1 SRP14 0 0 0 158 1 1
    PRKAB1 RPS11 0 0 0 184 1 1
    PRKAB1 DEPTOR 0 0 181 181 1 1
    PRKAB1 TNIP2 0 0 73 165 1 1
    PRKAB1 WDR59 0 0 0 200 1 1
    PRKAB1 PRKAR1A 0 540 0 588 1 2
    PRKAB1 DSC1 273 0 0 273 1 1
    PRKAB1 LRCH4 0 0 82 260 1 1
    PRKAB1 NOM1 0 0 142 223 1 1
    PRKAB1 WDR61 0 0 0 186 1 1
    PRKAB1 PIK3CD 0 0 0 210 1 1
    PRKAB1 INSRR 0 0 0 165 1 1
    PRKAB1 GNG3 0 600 0 600 1 1
    PRKAB1 PPP6C 0 0 57 330 1 1
    PRKAB1 GUSB 0 0 0 168 1 1
    PRKAB1 CCNG1 0 0 69 212 1 1
    PRKAB1 GSK3B 0 0 49 202 1 2
    PRKAB1 TTR 0 0 48 155 1 2
    PRKAB1 CDC34 0 0 0 155 1 1
    PRKAB1 NEK4 130 0 0 152 1 1
    PRKAB1 GNG10 0 600 0 600 1 1
    PRKAB1 SEPT7 0 0 0 152 1 1
    PRKAB1 ENSG00000268643 0 0 0 195 1 1
    PRKAB1 REN 0 0 54 230 1 1
    PRKAB1 COG7 0 0 0 241 1 1
    PRKAB1 ZNF142 0 0 66 182 1 1
    PRKAB1 EIF4B 0 0 0 193 1 1
    PRKAB1 CASP3 0 0 150 168 1 2
    PRKAB1 SLC45A3 0 0 0 192 1 1
    PRKAB1 HEPHL1 0 0 150 350 1 1
    PRKAB1 ATG101 0 600 140 649 1 2
    PRKAB1 PARS2 217 0 0 250 1 1
    PRKAB1 LTA4H 0 0 55 201 1 1
    PRKAB1 STK40 0 0 0 452 1 1
    PRKAB1 ACSL4 0 0 63 196 1 1
    PRKAB1 TFPT 0 0 155 260 1 1
    PRKAB1 RRAGB 0 900 0 907 1 2
    PRKAB1 TELO2 0 0 134 676 1 1
    PRKAB1 LDHA 0 0 108 187 1 1
    PRKAB1 TRMT61A 0 0 0 150 1 1
    PRKAB1 AMBRA1 0 900 131 909 1 2
    PRKAB1 UBE2M 0 0 0 209 1 1
    PRKAB1 ENSG00000273398 0 0 0 150 1 1
    PRKAB1 MASTL 0 0 74 235 1 1
    PRKAB1 KAT5 0 0 55 178 1 2
    PRKAB1 GNB4 0 600 0 662 1 1
    PRKAB1 DNAJC11 0 0 0 224 1 1
    PRKAB1 TMED4 0 0 0 254 1 1
    PRKAB1 TSSK6 0 0 0 452 1 1
    PRKAB1 NDUFS2 0 0 0 183 1 1
    PRKAB1 CEPT1 0 0 0 162 1 1
    PRKAB1 APMAP 0 0 123 211 1 1
    PRKAB1 UBE2O 217 0 62 313 1 1
    PRKAB1 ATP5L 0 0 0 183 1 1
    PRKAB1 BCAP29 0 0 113 211 1 1
    PRKAB1 MDM4 0 0 134 184 1 1
    PRKAB1 GOT2 0 0 66 159 1 1
    PRKAB1 TRIM45 0 0 0 192 1 1
    PRKAB1 NR1H4 0 0 0 173 1 1
    PRKAB1 HHEX 0 0 0 187 1 1
    PRKAB1 UBE2S 0 0 0 158 1 1
    PRKAB1 STRADB 0 900 0 906 1 1
    PRKAB1 CDC45 0 0 56 456 1 1
    PRKAB1 MST1R 105 0 0 241 1 1
    PRKAB1 PSKH1 0 0 67 161 1 1
    PRKAB1 AGL 213 0 0 288 1 1
    PRKAB1 HADHB 0 0 0 173 1 1
    PRKAB1 COX7A2L 0 0 0 340 1 1
    PRKAB1 UBC 0 0 75 151 1 1
    PRKAB1 MAP1LC3B 0 0 284 345 1 2
    PRKAB1 SNX13 0 0 0 150 1 1
    PRKAB1 CLK2 0 0 416 447 1 1
    PRKAB1 PKN3 0 0 0 167 1 1
    PRKAB1 RIPK4 0 0 0 163 1 1
    PRKAB1 ULK1 486 600 324 859 1 2
    PRKAB1 PKN1 0 0 56 263 1 1
    PRKAB1 PAQR3 0 0 71 209 1 2
    PRKAB1 CSNK2B 0 0 0 175 1 1
    PRKAB1 RGS2 0 0 123 218 1 1
    PRKAB1 PLIN2 0 900 46 900 1 1
    PRKAB1 NUAK1 0 0 211 242 1 1
    PRKAB1 PDK4 0 0 134 191 1 1
    PRKAB1 PIM2 0 0 0 452 1 2
    PRKAB1 CHKB 0 0 0 187 1 1
    PRKAB1 BMP8A 0 0 0 269 1 1
    PRKAB1 LGR5 0 0 0 187 1 1
    PRKAB1 PANK1 0 0 155 180 1 1
    PRKAB1 FA2H 0 0 0 158 1 1
    PRKAB1 ABCC2 0 0 0 157 1 1
    PRKAB1 PPARGC1A 0 900 391 936 1 1
    PRKAB1 PCK1 0 0 202 301 1 1
    PRKAB1 PPP1R7 0 0 0 161 1 1
    PRKAB1 PPP5C 0 0 0 192 1 1
    PRKAB1 PGA5 0 0 0 220 1 1
    PRKAB1 DUOXA1 0 0 96 187 1 1
    PRKAB1 LGMN 0 0 0 150 1 1
    PRKAB1 SLC35D2 0 0 0 202 1 1
    PRKAB1 SLC2A6 0 0 0 191 1 1
    PRKAB1 AP5M1 0 0 112 514 1 1
    PRKAB1 P4HB 0 0 47 196 1 2
    PRKAB1 G6PC 0 0 202 220 1 1
    PRKAB1 ENSG00000261832 0 0 60 162 1 1
    PRKAB1 RICTOR 0 0 413 453 1 2
    PRKAB1 PIM1 0 0 0 452 1 1
    PRKAB1 GNAQ 0 600 0 604 1 1
    PRKAB1 GNG11 0 600 0 600 1 1
    PRKAB1 GOLPH3 0 0 0 433 1 1
    PRKAB1 VPS39 0 0 0 152 1 1
    PRKAB1 NDUFS3 0 0 0 226 1 1
    PRKAB1 MTO1 0 0 83 166 1 1
    PRKAB1 CTSE 0 0 64 340 1 1
    PRKAB1 MOSPD2 0 0 0 150 1 1
    PRKAB1 STK11 0 900 603 976 1 2
    PRKAB1 SEC24C 0 0 94 182 1 1
    PRKAB1 POR 0 0 0 169 1 1
    PRKAB1 PLXNA2 0 0 0 189 1 1
    PRKAB1 PEX1 0 0 45 215 1 1
    PRKAB1 RB1CC1 0 600 233 687 1 2
    PRKAB1 MYL9 0 0 0 156 1 1
    PRKAB1 GNG12 0 600 0 603 1 1
    PRKAB1 ENSG00000254536 0 0 0 151 1 1
    PRKAB1 GNG4 0 600 0 600 1 1
    PRKAB1 SLC2A1 0 0 218 259 1 1
    PRKAB1 PPP1CC 0 0 48 353 1 1
    PRKAB1 MAP3K13 0 0 54 172 1 1
    PRKAB1 ALOX15 0 0 61 267 1 1
    PRKAB1 TIMM50 0 0 0 159 1 1
    PRKAB1 TP53 0 900 341 931 1 2
    PRKAB1 MDM2 0 0 231 237 1 1
    PRKAB1 EPS15 0 0 0 186 1 1
    PRKAB1 INSIG1 0 0 116 171 1 1
    PRKAB1 CTSA 0 0 0 229 1 1
    PRKAB1 MAP3K7 270 800 141 878 1 1
    PRKAB1 GPR128 0 0 113 304 1 1
    PRKAB1 STK36 0 0 95 156 1 1
    PRKAB1 ME2 0 0 114 174 1 1
    PRKAB1 PFKFB2 0 600 232 717 1 1
    PRKAB1 CTSW 0 0 0 161 1 1
    PRKAB1 MELK 0 0 141 509 1 1
    PRKAB1 PPARD 0 0 67 364 1 1
    PRKAB1 GHRL 0 0 181 181 1 1
    PRKAB1 SUCLG1 0 0 96 167 1 1
    PRKAB1 RHBDL3 0 0 0 162 1 1
    PRKAB1 RBMS1 0 0 94 221 1 1
    PRKAB1 HAGH 0 0 0 248 1 1
    PRKAB1 CPVL 0 0 0 229 1 1
    PRKAB1 LRTM1 0 0 171 210 1 1
    PRKAB1 GNGT1 0 600 0 600 1 1
    PRKAB1 PHKB 0 0 107 279 1 1
    PRKAB1 PRKAR2A 0 540 0 590 1 1
    PRKAB1 NDUFS1 0 0 0 193 1 1
    PRKAB1 MKRN1 0 0 86 185 1 1
    PRKAB1 SUMO2 0 0 81 153 1 1
    PRKAB1 UBE2G1 0 0 0 155 1 1
    PRKAB1 NR1H3 0 0 94 240 1 1
    PRKAB1 PASK 0 0 0 553 1 1
    PRKAB1 POLH 0 0 0 161 1 1
    PRKAB1 TGFBRAP1 0 0 0 167 1 1
    PRKAB1 KLC3 0 0 140 204 1 1
    PRKAB1 TMEM14C 0 0 120 220 1 1
    PRKAB1 ENSG00000258989 0 0 0 167 1 1
    PRKAB1 MFN2 0 0 57 167 1 2
    PRKAB1 TRIB2 0 0 0 452 1 1
    PRKAB1 NDUFC2 0 0 74 205 1 1
    PRKAB1 MTOR 0 900 435 953 1 2
    PRKAB1 ATP5D 0 0 92 206 1 1
    PRKAB1 MARK4 0 0 218 219 1 1
    PRKAB1 MAN2C1 0 0 0 155 1 1
    PRKAB1 KAT6B 0 0 0 150 1 1
    PRKAB1 SCPEP1 0 0 0 188 1 1
    PRKAB1 SOCS5 128 0 45 376 1 1
    PRKAB1 MTMR7 0 0 0 157 1 1
    PRKAB1 SLC45A4 0 0 0 192 1 1
    PRKAB1 PIK3C3 0 900 143 925 1 2
    PRKAB1 PPP4C 0 0 0 194 1 1
    PRKAB1 BCKDHB 0 0 95 181 1 1
    PRKAB1 ESRRA 0 0 117 261 1 1
    PRKAB1 PFKFB3 0 600 251 747 1 1
    PRKAB1 PPCS 0 0 0 183 1 1
    PRKAB1 SIRT2 0 0 73 198 1 2
    PRKAB1 UGDH 0 0 66 210 1 1
    PRKAB1 LPCAT1 0 0 161 218 1 1
    PRKAB1 DPAGT1 0 0 0 187 1 1
    PRKAB1 KCNE1 0 0 138 154 1 1
    PRKAB1 LAMTOR5 0 900 0 900 1 1
    PRKAB1 SLC38A9 0 900 0 907 1 1
    PRKAB1 MBOAT2 0 0 75 171 1 1
    PRKAB1 KAT6A 0 0 0 150 1 1
    PRKAB1 TOMM7 0 0 0 156 1 1
    PRKAB1 STRADA 0 900 362 945 1 1
    PRKAB1 PDHA1 62 0 113 179 1 1
    PRKAB1 NDUFA12 0 0 0 156 1 1
    PRKAB1 ZAP70 0 0 0 174 1 1
    PRKAB1 MOGS 0 0 0 312 1 1
    PRKAB1 TSSK3 0 0 0 452 1 1
    PRKAB1 TMED7 0 0 0 154 1 1
    PRKAB1 GAPDH 0 0 194 250 1 2
    PRKAB1 DAPK1 0 0 142 195 1 2
    PRKAB1 CTDSP2 0 0 0 212 1 1
    PRKAB1 TRIM11 160 0 0 159 1 1
    PRKAB1 MYH7B 0 0 0 170 1 1
    PRKAB1 LONP2 0 0 112 186 1 1
    PRKAB1 PYGB 0 0 0 158 1 1
    PRKAB1 SIK2 0 0 232 260 1 1
    PRKAB1 PIK3CG 0 0 81 569 1 1
    PRKAB1 JAK3 105 0 0 187 1 1
    PRKAB1 ABCC5 0 0 0 156 1 1
    PRKAB1 TEX2 0 0 0 157 1 1
    PRKAB1 DNTT 0 0 51 150 1 1
    PRKAB1 ARID5B 0 0 0 161 1 1
    PRKAB1 TBXAS1 0 0 60 279 1 1
    PRKAB1 SLC27A6 0 0 101 193 1 1
    PRKAB1 ENSG00000270024 0 0 0 213 1 1
    PRKAB1 PRKACB 0 0 194 272 1 1
    PRKAB1 ESYT2 0 0 0 159 1 1
    PRKAB1 PLCH2 0 0 0 153 1 1
    PRKAB1 MAST3 131 0 0 168 1 1
    PRKAB1 COX18 0 0 103 231 1 1
    PRKAB1 TBC1D4 0 0 219 219 1 1
    PRKAB1 GOLPH3L 0 0 0 151 1 1
    PRKAB1 CTSF 0 0 0 161 1 1
    PRKAB1 DCLRE1C 755 0 70 780 1 1
    PRKAB1 INSIG2 0 0 120 273 1 1
    PRKAB1 ZAK 0 0 0 222 1 1
    PRKAB1 MTX1 0 0 0 176 1 1
    PRKAB1 GNB1 0 600 0 662 1 1
    PRKAB1 PPP1R3D 0 0 447 483 1 1
    PRKAB1 HUNK 0 0 0 452 1 1
    PRKAB1 SUCLA2 0 0 94 151 1 1
    PRKAB1 TTLL7 0 0 113 276 1 1
    PRKAB1 ACTR5 0 0 123 259 1 1
    PRKAB1 ATG9A 0 0 0 176 1 2
    PRKAB1 KIAA1468 0 0 0 155 1 1
    PRKAB1 VPS28 0 0 0 153 1 1
    PRKAB1 SQSTM1 0 0 203 203 1 2
    PRKAB1 PCK2 0 0 140 226 1 1
    PRKAB1 LRRN1 0 0 90 272 1 1
    PRKAB1 MAPK3 0 0 108 257 1 2
    PRKAB1 ATG13 0 600 233 680 1 2
    PRKAB1 NPEPL1 0 0 0 151 1 1
    PRKAB1 ACSBG1 0 0 0 154 1 1
    PRKAB1 ESYT1 0 0 0 159 1 1
    PRKAB1 NCLN 0 0 158 222 1 1
    PRKAB1 CTBP1 0 0 0 222 1 1
    PRKAB1 HSP90AA1 0 0 292 303 1 2
    PRKAB1 ELAVL1 0 800 48 801 1 1
    PRKAB1 ALB 0 0 162 161 1 1
    PRKAB1 SERTAD3 0 0 155 177 1 1
    PRKAB1 MMS19 0 0 0 177 1 1
    PRKAB1 GNB2 0 600 0 671 1 1
    PRKAB1 PPP2R1B 0 0 67 170 1 1
    PRKAB1 ABCC3 0 0 0 157 1 1
    PRKAB1 MBLAC2 0 0 0 207 1 1
    PRKAB1 CRY2 0 600 0 600 1 1
    PRKAB1 ABCC4 0 0 0 156 1 1
    PRKAB1 SLC2A13 0 0 0 191 1 1
    PRKAB1 PRMT6 0 0 0 152 1 1
    PRKAB1 ACSS1 0 0 123 190 1 1
    PRKAB1 ADIPOR1 0 0 150 258 1 1
    PRKAB1 HKDC1 0 0 0 209 1 1
    PRKAB1 AP1M1 681 0 0 708 1 1
    PRKAB1 PRMT3 0 0 0 151 1 1
    PRKAB1 MSRB2 0 0 292 292 1 1
    PRKAB1 SCARB1 0 0 107 181 1 1
    PRKAB1 VPS35 41 0 0 187 1 1
    PRKAB1 CDK16 0 0 103 181 1 1
    PRKAB1 ZCCHC14 0 0 0 181 1 1
    PRKAB1 SDSL 0 0 0 170 1 1
    PRKAB1 ATXN10 0 0 0 181 1 1
    PRKAB1 EPM2A 0 0 320 324 1 1
    PRKAB1 PRKCZ 0 0 67 153 1 1
    PRKAB1 VPS26A 0 0 0 178 1 1
    PRKAB1 EMC6 0 0 0 164 1 1
    PRKAB1 MAP3K9 0 0 0 186 1 1
    PRKAB1 FKBP4 272 0 0 301 1 1
    PRKAB1 SGK494 0 0 0 303 1 1
    PRKAB1 PDE4D 0 0 60 197 1 1
    PRKAB1 SAMM50 0 0 0 158 1 1
    PRKAB1 SIRT6 0 0 74 185 1 1
    PRKAB1 AMD1 0 0 44 151 1 1
    PRKAB1 PEX5L 0 0 0 182 1 1
    PRKAB1 TRADD 0 0 60 225 1 1
    PRKAB1 PPP1CB 0 0 56 386 1 1
    PRKAB1 ABCC8 0 0 67 388 1 1
    PRKAB1 ROCK2 0 0 0 150 1 1
    PRKAB1 XRCC4 0 0 0 152 1 1
    PRKAB1 ZNF365 0 0 0 189 1 1
    PRKAB1 CHKA 0 0 54 193 1 1
    PRKAB1 PPP2CB 0 0 0 222 1 1
    PRKAB1 CRHR2 0 0 0 183 1 1
    PRKAB1 FSTL3 0 0 0 185 1 1
    PRKAB1 NDUFS7 0 0 150 192 1 1
    PRKAB1 EMC3 0 0 0 196 1 1
    PRKAB1 SESN2 0 600 466 787 1 2
    PRKAB1 CTDSPL 0 0 0 212 1 1
    PRKAB1 PLD1 0 0 75 173 1 1
    PRKAB1 PEX5 0 0 81 235 1 1
    PRKAB1 PTPRS 0 0 0 189 1 1
    PRKAB1 EPS15L1 0 0 0 246 1 1
    PRKAB1 NFRKB 0 0 103 241 1 1
    PRKAB1 FLCN 0 0 630 630 1 1
    PRKAB1 SESN3 0 600 134 655 1 1
    PRKAB1 CAMKK1 0 0 160 592 1 1
    PRKAB1 VPREB3 0 0 108 245 1 1
    PRKAB1 ZNF77 0 0 283 301 1 1
    PRKAB1 MT-ATP6 0 0 46 210 1 1
    PRKAB1 PPARA 0 0 278 338 1 1
    PRKAB1 HMGCL 0 0 55 213 1 1
    PRKAB1 CBR1 273 0 0 276 1 1
    PRKAB1 CRHR1 0 0 0 183 1 1
    PRKAB1 SRR 0 0 0 258 1 1
    PRKAB1 NHLRC1 0 0 204 232 1 1
    PRKAB1 CDK12 0 0 0 203 1 1
    PRKAB1 UBE2W 0 0 0 159 1 1
    PRKAB1 UCP3 0 0 82 186 1 1
    PRKAB1 COA8 0 0 82 150 1 1
    PRKAB1 GLS2 0 0 162 180 1 1
    PRKAB1 VCL 0 0 150 168 1 1
    PRKAB1 PHKA1 0 0 107 301 1 1
    PRKAB1 TSSK1B 0 0 0 452 1 1
    PRKAB1 CBSL 0 0 123 241 1 1
    PRKAB1 GNG13 0 600 0 600 1 1
    PRKAB1 LAMTOR3 0 900 0 919 1 1
    PRKAB1 PRDX2 0 0 0 207 1 1
    PRKAB1 PLEKHA4 270 0 0 270 1 1
    PRKAB1 BCL2A1 0 0 240 240 1 1
    PRKAB1 SNX25 0 0 0 165 1 1
    PRKAB1 ABCC6 0 0 0 157 1 1
    PRKAB1 PPEF2 0 0 53 201 1 1
    PRKAB1 ITSN2 0 0 0 266 1 1
    PRKAB1 PPP2R5C 0 0 447 460 1 1
    PRKAB1 GADD45A 0 0 150 199 1 1
    PRKAB1 PKM 0 0 150 186 1 1
    PRKAB1 WDR45 0 0 53 168 1 2
    PRKAB1 MAPK1 0 0 123 215 1 2
    PRKAB1 IGF1 0 0 193 193 1 1
    PRKAB1 PPP2CA 0 0 81 255 1 1
    PRKAB1 EIF4E 0 0 120 168 1 1
    PRKAB1 YWHAQ 0 0 0 156 1 1
    PRKAB1 COG2 0 0 112 256 1 1
    PRKAB1 FDXR 0 0 209 226 1 1
    PRKAB1 RRAD 0 0 59 277 1 1
    PRKAB1 HMGCR 0 800 235 843 1 1
    PRKAB1 UBE2I 0 0 0 152 1 1
    PRKAB1 RRM2B 0 0 161 187 1 1
    PRKAB1 NOS3 0 0 82 160 1 1
    PRKAB1 PPIP5K2 0 0 108 374 1 1
    PRKAB1 PRKAA1 911 900 851 999 1 2
    PRKAB1 TRIM61 0 0 213 213 1 1
    PRKAB1 NADSYN1 0 0 0 283 1 1
    PRKAB1 GNB2L1 0 0 81 172 1 1
    PRKAB1 ANXA7 0 0 0 183 1 2
    PRKAB1 RHEB 0 900 261 932 1 2
    PRKAB1 SMG7 0 0 0 155 1 1
    PRKAB1 TSSK2 0 0 94 482 1 1
    PRKAB1 PNP 0 0 0 152 1 1
    PRKAB1 TBK1 0 0 74 159 1 2
    PRKAB1 ADIPOR2 0 0 113 225 1 1
    PRKAB1 YTHDC2 0 0 0 176 1 1
    PRKAB1 GEMIN6 0 0 444 444 1 1
    PRKAB1 ACOT9 0 0 134 220 1 1
    PRKAB1 ENSG00000263020 0 0 0 175 1 1
    PRKAB1 APCDD1L 0 0 0 205 1 1
    PRKAB1 COG5 0 0 103 237 1 1
    PRKAB1 ABCC9 0 0 59 344 1 1
    PRKAB1 VDAC1 0 0 71 177 1 2
    PRKAB1 PRKCD 0 0 0 167 1 2
    PRKAB1 RFPL4A 0 0 203 217 1 1
    PRKAB1 PGA3 0 0 0 220 1 1
    PRKAB1 OXCT1 0 0 113 187 1 1
    PRKAB1 VDAC3 0 0 0 173 1 1
    PRKAB1 SLC2A4 0 0 390 410 1 1
    PRKAB1 ATXN2 0 0 0 225 1 1
    PRKAB1 GRIPAP1 0 0 0 179 1 1
    PRKAB1 FOXO3 0 600 241 721 1 2
    PRKAB1 ENSG00000250232 0 0 0 158 1 1
    PRKAB1 XRCC6BP1 0 0 0 155 1 1
    PRKAB1 CRY1 0 600 55 605 1 1
    PRKAB1 NECAB2 0 0 137 323 1 1
    PRKAB1 CUTA 484 0 0 486 1 1
    PRKAB1 PKMYT1 0 0 0 162 1 1
    PRKAB1 TMED9 0 0 0 154 1 1
    PRKAB1 EPT1 0 0 0 154 1 1
    PRKAB1 HARS2 130 0 0 158 1 1
    PRKAB1 MIF 0 0 247 246 1 1
    PRKAB1 ATG3 0 0 96 186 1 2
    PRKAB1 TRIM28 0 0 181 181 1 2
    PRKAB1 OSER1 0 0 0 151 1 1
    PRKAB1 POLR3GL 0 0 0 240 1 1
    PRKAB1 COMT 0 0 47 259 1 1
    PRKAB1 HNF4A 0 0 127 196 1 1
    PRKAB1 PPP3CA 0 0 0 191 1 1
    PRKAB1 RALY 0 0 0 158 1 1
    PRKAB1 HMGA1 0 0 160 159 1 1
    PRKAB1 BMP8B 0 0 0 269 1 1
    PRKAB1 EIF4EBP1 0 0 324 338 1 1
    PRKAB1 FOXO4 0 600 55 623 1 1
    PRKAB1 PDE4B 0 0 0 154 1 1
    PRKAB1 TMEM233 0 0 233 232 1 1
    PRKAB1 APOL4 0 0 156 178 1 1
    PRKAB1 PPM1E 0 0 88 184 1 1
    PRKAB1 CTSO 0 0 0 161 1 1
    PRKAB1 GJA5 0 0 0 278 1 1
    PRKAB1 WDR20 0 0 0 159 1 1
    PRKAB1 CTDP1 0 0 0 159 1 1
    PRKAB1 CPT1A 0 0 157 166 1 1
    PRKAB1 WEE2 0 0 0 172 1 1
    PRKAB1 UQCRFS1 0 0 0 178 1 1
    PRKAB1 WDTC1 0 0 0 153 1 1
    PRKAB1 CYP8B1 0 0 0 195 1 1
    PRKAB1 ACACB 0 800 235 849 1 1
    PRKAB1 PARL 0 0 0 155 1 1
    PRKAB1 SLC2A12 0 0 0 191 1 1
    PRKAB1 PDIA3 0 0 45 156 1 1
    PRKAB1 RRAGD 0 900 0 903 1 1
    PRKAB1 CHCHD10 0 0 89 181 1 1
    PRKAB1 HDHD2 0 0 0 271 1 1
    PRKAB1 USMG5 0 0 0 179 1 1
    PRKAB1 PIK3CB 0 0 53 336 1 1
    PRKAB1 EMC1 0 0 0 169 1 1
    PRKAB1 PIM3 0 0 0 452 1 1
    PRKAB1 PRKCH 0 0 0 178 1 1
    PRKAB1 MET 0 0 46 190 1 1
    PRKAB1 LRRK2 0 0 0 184 1 2
    PRKAB1 STK38L 0 0 90 294 1 1
    PRKAB1 PGLS 0 0 0 184 1 1
    PRKAB1 SF3B3 0 0 0 152 1 1
    PRKAB1 EEF2K 0 800 0 808 1 2
    PRKAB1 WEE1 0 0 0 172 1 1
    PRKAB1 FOXO1 0 600 142 642 1 2
    PRKAB1 SOD2 0 0 66 205 1 1
    PRKAB1 PICALM 0 0 45 209 1 1
    PRKAB1 GNG5 0 600 0 608 1 1
    PRKAB1 RRAGC 0 900 90 912 1 1
    PRKAB1 CRKL 0 0 44 341 1 1
    PRKAB1 LMAN2L 0 0 0 175 1 1
    PRKAB1 GNGT2 0 600 0 600 1 1
    PRKAB1 LAMTOR1 0 900 113 926 1 1
    PRKAB1 TMEM115 0 0 0 159 1 1
    PRKAB1 NDRG3 0 0 95 159 1 1
    PRKAB1 FBP1 0 0 90 172 1 1
    PRKAB1 TSPO 0 0 0 155 1 1
    PRKAB1 PI4KA 0 0 74 496 1 1
    PRKAB1 STK24 0 0 193 244 1 1
    PRKAB1 PGM3 0 0 0 169 1 1
    PRKAB1 ENSG00000250644 0 0 0 236 1 1
    PRKAB1 CUL3 0 0 74 151 1 1
    PRKAB1 CHUK 0 0 108 190 1 1
    PRKAB1 STAMBPL1 0 0 0 158 1 1
    PRKAB1 CALM2 0 0 94 165 1 1
    PRKAB1 TBC1D1 0 900 424 939 1 1
    PRKAB1 MPC2 0 0 67 272 1 1
    PRKAB1 SIK1 0 0 158 189 1 1
    PRKAB1 AAK1 0 0 66 175 1 1
    PRKAB1 VIL1 0 0 70 187 1 1
    PRKAB1 ALOX5 0 0 95 233 1 1
    PRKAB1 PRKCQ 0 0 0 167 1 2
    PRKAB1 COMTD1 0 0 0 256 1 1
    PRKAB1 ATG12 0 0 193 233 1 2
    PRKAB1 PRMT2 0 0 0 151 1 1
    PRKAB1 LIMK1 0 0 0 174 1 1
    PRKAB1 PDE4DIP 0 0 95 250 1 1
    PRKAB1 KAT8 0 0 48 157 1 2
    PRKAB1 AP1G1 680 0 0 689 1 1
    PRKAB1 PLIN3 0 900 91 909 1 1
    PRKAB1 TRIB3 0 0 0 452 1 1
    PRKAB1 DBI 0 0 0 155 1 1
    PRKAB1 STXBP5L 0 0 0 189 1 1
    PRKAB1 PTEN 0 0 322 330 1 2
    PRKAB1 RIMS2 0 0 180 179 1 1
    PRKAB1 VPS26B 0 0 0 162 1 1
    PRKAB1 WIPI1 0 0 120 156 1 2
    PRKAB1 DNM1L 0 0 113 153 1 2
    PRKAB1 PRKAA2 973 900 654 999 1 2
    PRKAB1 CCKBR 498 0 0 497 1 1
    PRKAB1 C12orf5 0 0 282 282 1 1
    PRKAB1 SDCCAG3 217 0 0 217 1 1
    PRKAB1 LEP 0 900 194 915 1 1
    PRKAB1 NFKBIA 0 0 116 166 1 1
    PRKAB1 RCHY1 0 0 96 171 1 1
    PRKAB1 MAPK14 0 0 81 287 1 1
    PRKAB1 MAPK10 0 0 0 214 1 2
    PRKAB1 UCP1 0 0 138 259 1 1
    PRKAB1 SREBF1 0 0 321 369 1 2
    PRKAB1 CTSD 0 0 0 236 1 2
    PRKAB1 AXIN1 0 0 123 160 1 1
    PRKAB1 ATM 0 0 167 167 1 1
    PRKAB1 DAP 0 0 90 287 1 2
    PRKAB1 PRKAG3 824 800 684 996 1 1
    PRKAB1 LCAT 0 0 74 238 1 1
    PRKAB1 EPHA6 0 0 94 177 1 1
    PRKAB1 SIK3 0 0 261 317 1 1
    PRKAB1 PNKP 0 0 0 168 1 1
    PRKAB1 ATG7 0 0 194 260 1 2
    PRKAB1 ACTG1 0 0 244 250 1 1
    PRKAB1 WDR7 0 0 0 174 1 1
    PRKAB1 CPT1C 0 0 112 201 1 1
    PRKAB1 FMN1 0 0 0 168 1 1
    PRKAB1 DMWD 0 0 137 346 1 1
    PRKAB1 UBE2J2 0 0 0 159 1 1
    PRKAB1 SOCS6 0 0 45 193 1 1
    PRKAB1 LAMC3 0 0 0 155 1 1
    PRKAB1 SNAP91 0 0 0 151 1 1
    PRKAB1 SMG6 0 0 0 155 1 1
    PRKAB1 LRTOMT 0 0 0 254 1 1
    PRKAB1 MTMR8 0 0 0 157 1 1
    PRKAB1 SUGT1 0 0 0 212 1 1
    PRKAB1 RPS6KA1 0 0 163 163 1 1
    PRKAB1 ELP6 0 0 0 177 1 1
    PRKAB1 NR2E3 0 0 0 256 1 1
    PRKAB1 FNIP1 270 0 646 730 1 1
    PRKAB1 PSMD14 43 0 0 179 1 1
    PRKAB1 TGM3 213 0 0 213 1 1
    PRKAB1 DYNLL2 0 900 0 911 1 1
    PRKAB1 CARKD 0 0 0 154 1 1
    PRKAB1 AKT3 0 0 0 172 1 1
    PRKAB1 SEC22B 0 0 0 158 1 1
    PRKAB1 ACOX1 0 0 134 217 1 1
    PRKAB1 SIRT1 0 0 284 432 1 2
    PRKAB1 PGM2L1 0 0 0 212 1 1
    PRKAB1 MCL1 685 0 63 692 1 2
    PRKAB1 DCP1B 0 0 0 248 1 1
    PRKAB1 COG3 0 0 91 244 1 1
    PRKAB1 BACE1 0 0 0 220 1 1
    PRKAB1 GNG8 0 600 0 600 1 1
    PRKAB1 PPP1CA 0 0 73 379 1 1
    PRKAB1 UGGT1 0 0 0 177 1 1
    PRKAB1 KSR1 0 0 92 175 1 1
    PRKAB1 ATG5 0 0 209 231 1 2
    PRKAB1 PPP5D1 0 0 0 192 1 1
    PRKAB1 HIPK2 0 0 96 196 1 1
    PRKAB1 GBE1 0 0 0 160 1 1
    PRKAB1 PRKAG2 870 900 710 999 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0019901 Molecular Function protein kinase binding enables IBA
    GO:0031669 Biological Process cellular response to nutrient levels involved_in IDA
    GO:0031669 Biological Process cellular response to nutrient levels involved_in ISS
    GO:0031669 Biological Process cellular response to nutrient levels involved_in NAS
    GO:0006633 Biological Process fatty acid biosynthetic process involved_in IEA
    GO:0035878 Biological Process nail development involved_in IEA
    GO:0120162 Biological Process positive regulation of cold-induced thermogenesis involved_in ISS
    GO:0007165 Biological Process signal transduction involved_in IBA
    GO:0005737 Cellular Component cytoplasm is_active_in IBA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:0031588 Cellular Component nucleotide-activated protein kinase complex part_of IBA
    GO:0031588 Cellular Component nucleotide-activated protein kinase complex part_of IPI
    GO:0031588 Cellular Component nucleotide-activated protein kinase complex part_of ISS
    GO:0005634 Cellular Component nucleus is_active_in IBA
    GO:0005634 Cellular Component nucleus located_in IDA
    Pathways
    Name DB ID
    Neurotransmitter receptors and postsynaptic signal transmission Reactome R-HSA-112314
    Transmission across Chemical Synapses Reactome R-HSA-112315
    Neuronal System Reactome R-HSA-112316
    Translocation of SLC2A4 (GLUT4) to the plasma membrane Reactome R-HSA-1445148
    Mitochondrial biogenesis Reactome R-HSA-1592230
    Signal Transduction Reactome R-HSA-162582
    Macroautophagy Reactome R-HSA-1632852
    MTOR signalling Reactome R-HSA-165159
    Organelle biogenesis and maintenance Reactome R-HSA-1852241
    Membrane Trafficking Reactome R-HSA-199991
    Generic Transcription Pathway Reactome R-HSA-212436
    Activation of PPARGC1A (PGC-1alpha) by phosphorylation Reactome R-HSA-2151209
    Transcriptional Regulation by TP53 Reactome R-HSA-3700989
    Energy dependent regulation of mTOR by LKB1-AMPK Reactome R-HSA-380972
    Post NMDA receptor activation events Reactome R-HSA-438064
    Activation of NMDA receptors and postsynaptic events Reactome R-HSA-442755
    TP53 Regulates Metabolic Genes Reactome R-HSA-5628897
    Regulation of TP53 Activity Reactome R-HSA-5633007
    Vesicle-mediated transport Reactome R-HSA-5653656
    Regulation of TP53 Activity through Phosphorylation Reactome R-HSA-6804756
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Gene expression (Transcription) Reactome R-HSA-74160
    Autophagy Reactome R-HSA-9612973
    Lipophagy Reactome R-HSA-9613354
    Activation of AMPK downstream of NMDARs Reactome R-HSA-9619483
    Selective autophagy Reactome R-HSA-9663891
    p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
    Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850) WikiPathways WP3850_r121711
    Thermogenesis (WP4321) WikiPathways WP4321_r123362
    Hippo signaling regulation pathways (WP4540) WikiPathways WP4540_r120395
    Leptin and adiponectin (WP3934) WikiPathways WP3934_r107151
    Sterol regulatory element-binding proteins (SREBP) signaling (WP1982) WikiPathways WP1982_r116442
    Lipid metabolism pathway (WP3965) WikiPathways WP3965_r117154
    Hereditary leiomyomatosis and renal cell carcinoma pathway (WP4206) WikiPathways WP4206_r123458
    AMP-activated protein kinase signaling (WP1403) WikiPathways WP1403_r123620
    Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
    Energy metabolism (WP1541) WikiPathways WP1541_r117711
    Autophagy (WP4923) WikiPathways WP4923_r110416
    Synaptic signaling pathways associated with autism spectrum disorder (WP4539) WikiPathways WP4539_r113659
    Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
    Angiopoietin-like protein 8 regulatory pathway (WP3915) WikiPathways WP3915_r123920
    1q21.1 copy number variation syndrome (WP4905) WikiPathways WP4905_r115772
    Target of rapamycin signaling (WP1471) WikiPathways WP1471_r123616
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_005253909 2 mRNA transcript variant X1 NC_000012 Reference
    NM_006253 5 mRNA None NC_000012 Reference