STK26

serine/threonine kinase 26
General Information
Name serine/threonine kinase 26
Alias
  • serine/threonine-protein kinase 26
  • Mst3 and SOK1-related kinase
  • STE20-like kinase 4
  • STE20-like kinase MST4
  • mammalian Ste20-like protein kinase 4
  • mammalian sterile 20-like 4
  • serine/threonine protein kinase 26
  • serine/threonine protein kinase MST4
  • serine/threonine-protein kinase MASK
Synonyms MST4 MASK
Gene_family STRIPAK complex
organism Homo sapiens
entrez_id 51765
location Xq26.2
transcript_count 5
exon_count 13
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
      nextProt Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed:11641781, PubMed:17360971). Modulates apoptosis (PubMed:11641781, PubMed:17360971). In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Phosphorylates ATG4B at 'Ser-383', thereby increasing autophagic flux (PubMed:29232556).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    STK26 BioGRID STK25 GeneID BioGRID Affinity Capture-MS; Cross-Linking-MS (XL-MS)
    STK26 BioGRID ATP2B1 GeneID BioGRID Cross-Linking-MS (XL-MS)
    STK26 BioGRID C9orf72 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID SERBP1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID Cebpb GeneID BioGRID Protein-peptide
    STK26 BioGRID CCT7 GeneID BioGRID Cross-Linking-MS (XL-MS)
    STK26 BioGRID NEFM GeneID BioGRID Cross-Linking-MS (XL-MS)
    STK26 BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    STK26 BioGRID RPA2 GeneID BioGRID Proximity Label-MS
    STK26 BioGRID RPA1 GeneID BioGRID Proximity Label-MS
    STK26 BioGRID CFTR GeneID BioGRID PCA
    STK26 BioGRID CLEC16A GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID RICTOR GeneID BioGRID Proximity Label-MS
    STK26 BioGRID PDCD10 GeneID BioGRID Affinity Capture-MS; Co-fractionation; Two-hybrid
    STK26 BioGRID RBM4B GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FDXR GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STIP1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STRIP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    STK26 BioGRID CTTNBP2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    STK26 BioGRID SIKE1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TAOK1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STRIP2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CTTNBP2NL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    STK26 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TAOK3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STRN3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STRN4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID LATS2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FGFR1OP2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MOB4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TAOK2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STK24 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID SLMAP GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STRN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    STK26 BioGRID PPP2R1A GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID IGFBP3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID GOLGA2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
    STK26 BioGRID MAVS GeneID BioGRID Affinity Capture-Western
    STK26 BioGRID BAP1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ACBD3 GeneID BioGRID Co-fractionation
    STK26 BioGRID CCAR2 GeneID BioGRID Co-fractionation
    STK26 BioGRID GOPC GeneID BioGRID Co-fractionation
    STK26 BioGRID POLE3 GeneID BioGRID Co-fractionation
    STK26 BioGRID LARP1 GeneID BioGRID Co-fractionation
    STK26 BioGRID SLC4A1AP GeneID BioGRID Co-fractionation
    STK26 BioGRID BRD8 GeneID BioGRID Co-fractionation
    STK26 BioGRID HSPH1 GeneID BioGRID Co-fractionation
    STK26 BioGRID NCKAP1 GeneID BioGRID Co-fractionation
    STK26 BioGRID SMC2 GeneID BioGRID Co-fractionation
    STK26 BioGRID ARFGEF1 GeneID BioGRID Co-fractionation
    STK26 BioGRID SF3A1 GeneID BioGRID Co-fractionation
    STK26 BioGRID MATR3 GeneID BioGRID Co-fractionation
    STK26 BioGRID DDX23 GeneID BioGRID Co-fractionation
    STK26 BioGRID EIF4G3 GeneID BioGRID Co-fractionation
    STK26 BioGRID TJP1 GeneID BioGRID Co-fractionation
    STK26 BioGRID PSMD11 GeneID BioGRID Co-fractionation
    STK26 BioGRID PPP4C GeneID BioGRID Co-fractionation
    STK26 BioGRID PPP1CB GeneID BioGRID Co-fractionation
    STK26 BioGRID P4HB GeneID BioGRID Co-fractionation
    STK26 BioGRID EIF4G1 GeneID BioGRID Co-fractionation
    STK26 BioGRID CTTN GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CAPZB GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CAPZA2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CAPZA1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID RTN3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ACTR2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ACTR3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC1B GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC5 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID HOMER1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MAP4K4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DYNLL1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CCDC6 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID SRP54 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PTPN13 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PPP2R1B GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PPP2CB GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PPP2CA GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID GLUL GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID HSPE1-MOB4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC4-TTLL3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FRYL GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DYNLL2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC5L GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ILRUN GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID GNG2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MINK1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ARPC1A GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID vpr GeneID BioGRID Proximity Label-MS
    STK26 BioGRID SMAD4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID LAMP2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID GZMH GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID GIP GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID EP300 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID BBS1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ATP5PB GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID HNRNPCL2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FAM174A GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID NLRP10 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID KRT73 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PROSER2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CCM2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID UBXN6 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TRAF3IP3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MAGIX GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID RIPOR1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ZBTB2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID UNC45A GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PGCKA1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ANKRD49 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FAM135B GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MRPL42 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FILIP1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID B3GAT1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID NPTN GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ZIM2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID NTNG1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID SNRNP27 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DNAJB6 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID MED17 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CES2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID VBP1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID S100P GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID S100A6 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID RGS2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID NPAS1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DDRGK1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID OGT GeneID BioGRID Reconstituted Complex
    STK26 BioGRID EBNA-1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID FAM20C GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID COPS5 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID KIF14 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID KIF23 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TRIM28 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID LMBR1L GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PLK1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CDC37 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CDK9 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID RIPK4 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DLD GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID DUSP19 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID BMP7 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID STK26 GeneID BioGRID Biochemical Activity
    STK26 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    STK26 BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
    STK26 BioGRID TRIM27 GeneID BioGRID Two-hybrid
    STK26 BioGRID DCTN1 GeneID BioGRID Proximity Label-MS
    STK26 BioGRID Strn3 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID Ruvbl1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID Ppp2ca GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TEPSIN GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CEP76 GeneID BioGRID Two-hybrid
    STK26 BioGRID NDUFAF1 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID CEP152 GeneID BioGRID Proximity Label-MS
    STK26 BioGRID IKZF3 GeneID BioGRID Two-hybrid
    STK26 BioGRID GRB14 GeneID BioGRID Two-hybrid
    STK26 BioGRID SLC25A41 GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID TTC4 GeneID BioGRID Co-fractionation
    STK26 BioGRID RPL12 GeneID BioGRID Co-fractionation
    STK26 BioGRID MAPK9 GeneID BioGRID Co-fractionation
    STK26 BioGRID MOS GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID EGFR GeneID BioGRID Affinity Capture-MS
    STK26 BioGRID YWHAE GeneID BioGRID Co-fractionation
    STK26 BioGRID PTMA GeneID BioGRID Co-fractionation
    STK26 BioGRID MYO1E GeneID BioGRID Co-fractionation
    STK26 BioGRID TBCB GeneID BioGRID Co-fractionation
    STK26 BioGRID CAPNS1 GeneID BioGRID Co-fractionation
    STK26 BioGRID CAPN2 GeneID BioGRID Co-fractionation
    STK26 BioGRID ATIC GeneID BioGRID Co-fractionation
    STK26 BioGRID ASNS GeneID BioGRID Co-fractionation
    STK26 BioGRID SCPEP1 GeneID BioGRID Co-fractionation
    STK26 BioGRID OGFOD1 GeneID BioGRID Co-fractionation
    STK26 BioGRID UBXN1 GeneID BioGRID Co-fractionation
    STK26 BioGRID ISOC1 GeneID BioGRID Co-fractionation
    STK26 BioGRID MCTS1 GeneID BioGRID Co-fractionation
    STK26 BioGRID TWF2 GeneID BioGRID Co-fractionation
    STK26 BioGRID PLPBP GeneID BioGRID Co-fractionation
    STK26 BioGRID TUBB3 GeneID BioGRID Co-fractionation
    STK26 BioGRID PDIA4 GeneID BioGRID Co-fractionation
    STK26 BioGRID SRPK1 GeneID BioGRID Biochemical Activity
    STK26 BioGRID APP GeneID BioGRID Reconstituted Complex
    STK26 BioGRID PTPA GeneID BioGRID Affinity Capture-Western
    STK26 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
    STK26 BioGRID NEDD4 GeneID BioGRID Reconstituted Complex
    STK26 BioGRID Dynll1 GeneID BioGRID Affinity Capture-MS
    STK26 None STK26 GeneID HPRD None
    STK26 None STK26 GeneID HPRD None
    STK26 None GOLGA2 GeneID HPRD None
    STK26 None RAF1 GeneID HPRD None
    STK26 None MBP GeneID HPRD None
    STK26 BioGRID RAF1 GeneID BioGRID Two-hybrid
    STK26 BioGRID EPHB2 GeneID BioGRID Phenotypic Enhancement
    STK26 Protein STK26 GeneID BIND Mst4 autophosphorylates.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    MST4 MAPK10 0 0 47 163 2 1
    MST4 PRKAA2 0 0 69 185 2 1
    MST4 CAPNS1 245 0 0 270 2 1
    MST4 SIRT1 0 0 0 193 2 1
    MST4 TRAF3 0 0 120 166 2 1
    MST4 LRRK2 270 0 75 438 2 1
    MST4 ATG4D 0 0 155 174 2 1
    MST4 TRIM28 270 0 0 286 2 1
    MST4 MAPK1 0 0 113 295 2 1
    MST4 PRKAA1 0 0 0 172 2 1
    MST4 CDK5 0 0 123 177 2 1
    MST4 MAPK8 0 0 49 184 2 1
    MST4 MAP1S 0 0 0 167 2 1
    MST4 TRAF6 270 0 292 516 2 1
    MST4 AURKA 0 0 45 204 2 1
    MST4 MAPK3 0 0 123 310 2 1
    MST4 P4HB 0 0 0 174 2 1
    MST4 STK11 0 900 556 931 2 1
    MST4 RAF1 192 0 48 314 2 1
    MST4 DCN 0 0 0 268 2 1
    MST4 TP53 0 0 82 177 2 1
    MST4 RAB8A 0 0 193 237 2 1
    MST4 DAPK2 0 0 0 174 2 1
    MST4 CAMK2A 0 0 0 168 2 1
    MST4 PIM2 0 0 81 198 2 1
    MST4 BECN1 0 0 95 247 2 1
    MST4 GSK3B 0 0 0 207 2 1
    MST4 EPHB2 209 0 81 253 2 1
    MST4 CASP3 0 900 387 937 2 1
    MST4 MAPK15 0 0 218 262 2 1
    MST4 AKT1 0 0 210 240 2 1
    MST4 ATG4B 0 0 321 365 2 1
    MST4 ULK3 0 0 0 165 2 1
    MST4 RPS6KB1 0 0 139 211 2 1
    MST4 PDPK1 0 0 0 165 2 1
    MST4 DAPK3 0 0 75 174 2 1
    MST4 RPS6KB2 0 0 72 207 2 1
    MST4 MAPK9 272 0 60 388 2 1
    MST4 ATG4A 0 0 162 181 2 1
    MST4 CAPN2 244 0 0 277 2 1
    MST4 TRIM13 0 0 74 189 2 1
    MST4 LRSAM1 0 0 0 269 2 1
    MST4 ATIC 245 0 0 245 2 1
    MST4 TAB3 0 0 57 160 2 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0004676 Molecular Function 3-phosphoinositide-dependent protein kinase activity enables IEA
    GO:0004679 Molecular Function AMP-activated protein kinase activity enables IEA
    GO:0005524 Molecular Function ATP binding enables IDA
    GO:0004677 Molecular Function DNA-dependent protein kinase activity enables IEA
    GO:0072518 Molecular Function Rho-dependent protein serine/threonine kinase activity enables IEA
    GO:0004694 Molecular Function eukaryotic translation initiation factor 2alpha kinase activity enables IEA
    GO:0044024 Molecular Function histone H2AS1 kinase activity enables IEA
    GO:0072371 Molecular Function histone H2AS121 kinase activity enables IEA
    GO:1990244 Molecular Function histone H2AT120 kinase activity enables IEA
    GO:0035979 Molecular Function histone H2AXS139 kinase activity enables IEA
    GO:0044025 Molecular Function histone H2BS14 kinase activity enables IEA
    GO:0140823 Molecular Function histone H2BS36 kinase activity enables IEA
    GO:0035175 Molecular Function histone H3S10 kinase activity enables IEA
    GO:0044022 Molecular Function histone H3S28 kinase activity enables IEA
    GO:0140855 Molecular Function histone H3S57 kinase activity enables IEA
    GO:0035402 Molecular Function histone H3T11 kinase activity enables IEA
    GO:0072354 Molecular Function histone H3T3 kinase activity enables IEA
    GO:0140857 Molecular Function histone H3T45 kinase activity enables IEA
    GO:0035403 Molecular Function histone H3T6 kinase activity enables IEA
    GO:0044023 Molecular Function histone H4S1 kinase activity enables IEA
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0000287 Molecular Function magnesium ion binding enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0042803 Molecular Function protein homodimerization activity enables IPI
    GO:0004672 Molecular Function protein kinase activity enables IDA
    GO:0004672 Molecular Function protein kinase activity enables IMP
    GO:0106310 Molecular Function protein serine kinase activity enables IEA
    GO:0004674 Molecular Function protein serine/threonine kinase activity enables IBA
    GO:0004711 Molecular Function ribosomal protein S6 kinase activity enables IEA
    GO:0006915 Biological Process apoptotic process involved_in IEA
    GO:0034599 Biological Process cellular response to oxidative stress involved_in IDA
    GO:0009267 Biological Process cellular response to starvation involved_in IMP
    GO:0006338 Biological Process chromatin remodeling involved_in IEA
    GO:0035556 Biological Process intracellular signal transduction involved_in IBA
    GO:0035556 Biological Process intracellular signal transduction involved_in IMP
    GO:0030033 Biological Process microvillus assembly involved_in IDA
    GO:0030336 Biological Process negative regulation of cell migration involved_in IBA
    GO:0030336 Biological Process negative regulation of cell migration involved_in IMP
    GO:0046777 Biological Process protein autophosphorylation involved_in IMP
    GO:0006468 Biological Process protein phosphorylation involved_in IDA
    GO:0042981 Biological Process regulation of apoptotic process involved_in IDA
    GO:0090443 Cellular Component FAR/SIN/STRIPAK complex part_of IDA
    GO:0005794 Cellular Component Golgi apparatus is_active_in IBA
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0005798 Cellular Component Golgi-associated vesicle located_in IDA
    GO:0016324 Cellular Component apical plasma membrane located_in IDA
    GO:0071944 Cellular Component cell periphery located_in IDA
    GO:0005737 Cellular Component cytoplasm is_active_in IBA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0048471 Cellular Component perinuclear region of cytoplasm located_in IDA
    GO:0012506 Cellular Component vesicle membrane located_in TAS
    Pathways
    Name DB ID
    Apoptosis Reactome R-HSA-109581
    Apoptotic cleavage of cellular proteins Reactome R-HSA-111465
    Programmed Cell Death Reactome R-HSA-5357801
    Apoptotic execution phase Reactome R-HSA-75153
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_016542 4 mRNA transcript variant 1 NC_000023 Reference
    NM_001042453 2 mRNA transcript variant 2 NC_000023 Reference
    XM_047442155 1 mRNA transcript variant X1 NC_000023 Reference
    XM_047442156 1 mRNA transcript variant X2 NC_000023 Reference
    NM_001042452 2 mRNA transcript variant 3 NC_000023 Reference