TRIM17

tripartite motif containing 17
General Information
Name tripartite motif containing 17
Alias
  • E3 ubiquitin-protein ligase TRIM17
  • RING finger protein terf
  • RING-type E3 ubiquitin transferase TRIM17
  • ring finger protein 16
  • testis RING finger protein
  • tripartite motif-containing protein 17
Synonyms terf RBCC RNF16
Gene_family Ring finger proteins|Tripartite motif family
organism Homo sapiens
entrez_id 51127
location 1q42.13
transcript_count 13
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein is expressed almost exclusively in the testis, but its function is unknown. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
      Stringdb E3 ubiquitin-protein ligase TRIM17; May function as a ubiquitin E3 ligase; Belongs to the TRIM/RBCC family
      nextProt E3 ubiquitin ligase that plays important roles in the regulation of neuronal apoptosis, selective autophagy or cell proliferation (PubMed:22023800, PubMed:19358823, PubMed:27562068). Stimulates the degradation of kinetochore ZW10 interacting protein ZWINT in a proteasome-dependent manner, leading to negative regulation of cell proliferation (PubMed:22023800). Inhibits autophagic degradation of diverse known targets while contributing to autophagy of midbodies. Autophagy-inhibitory activity involves MCL1, which TRIM17 assembles into complexes with the key autophagy regulator BECN1 (PubMed:27562068). Controls neuronal apoptosis by mediating ubiquitination and degradation of MCL1 to initiate neuronal death. In addition, regulates NFAT transcription factors NFATC3 and NFATC4 activities by preventing their nuclear localization, thus inhibiting their transcriptional activities. Decreases TRIM41-mediated degradation of ZSCAN2 thereby stimulating alpha-synuclein/SNCA transcription in neuronal cells (By similarity). Prevents the E3 ubiquitin-ligase activity of TRIM28 and its interaction with anti-apoptotic BCL2A1, blocking TRIM28 from ubiquitinating BCL2A1 (PubMed:19358823).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    TRIM17 BioGRID SUSD2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID MYDGF GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RNF31 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID TOR4A GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID NOP58 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID TRIM17 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RPS27L GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID EHD4 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID MRPL22 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID DBNL GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID MRPS18B GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID NECAP1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID GTPBP4 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID EXOSC2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID WDFY3 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID LYPLA2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SPIN1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID DCAF7 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID USPL1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SPCS2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SLK GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID ATP5MF GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID UBE2E1 GeneID BioGRID Reconstituted Complex; Two-hybrid
    TRIM17 BioGRID TSG101 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SRPK1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SNRPD1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RPS27 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RPL30 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RCN2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RANBP1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID RAB1A GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID PEPD GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID LYZ GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID LUM GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID STMN1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID NDST1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID PPP1R42 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID ASPM GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID CDAN1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID IMP4 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SELENOI GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID CCDC142 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID LRCH3 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID SLC25A31 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID EPS8L3 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID MRPL11 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID CARD18 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID TOMM22 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID GPX4 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID GMFB GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID BAX GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    TRIM17 BioGRID RBM38 GeneID BioGRID Affinity Capture-Western
    TRIM17 BioGRID TRIM44 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
    TRIM17 BioGRID MTMR1 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID CAMK4 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
    TRIM17 BioGRID TRIM41 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID TRIM39 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID HGS GeneID BioGRID Two-hybrid
    TRIM17 BioGRID MEOX2 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA
    TRIM17 BioGRID VDAC3 GeneID BioGRID Co-fractionation
    TRIM17 BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western; Co-localization
    TRIM17 BioGRID BCL2A1 GeneID BioGRID Affinity Capture-Western
    TRIM17 BioGRID LGALS8 GeneID BioGRID Reconstituted Complex
    TRIM17 BioGRID LGALS3 GeneID BioGRID Reconstituted Complex
    TRIM17 BioGRID SNX2 GeneID BioGRID Affinity Capture-MS
    TRIM17 BioGRID UBC GeneID BioGRID Biochemical Activity
    TRIM17 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Luminescence
    TRIM17 BioGRID USP15 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID UBE2N GeneID BioGRID Reconstituted Complex
    TRIM17 BioGRID UBE2D2 GeneID BioGRID Reconstituted Complex; Two-hybrid
    TRIM17 BioGRID UBE2D1 GeneID BioGRID Reconstituted Complex; Two-hybrid
    TRIM17 BioGRID LRSAM1 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID TRAF6 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID MNAT1 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID UBE2D3 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID ZWINT GeneID BioGRID Affinity Capture-Western
    TRIM17 BioGRID UBE2W GeneID BioGRID Two-hybrid
    TRIM17 BioGRID UBE2D4 GeneID BioGRID Two-hybrid
    TRIM17 BioGRID UBE2H GeneID BioGRID Two-hybrid
    TRIM17 Protein TRIM39 GeneID HPRD None
    StringDB
    A B experiments database textmining combined score hadb nhadb
    TRIM17 MYO5B 0 0 108 152 1 1
    TRIM17 DAXX 0 0 394 409 1 1
    TRIM17 PPIA 0 0 420 583 1 1
    TRIM17 KLHL20 0 0 188 188 1 1
    TRIM17 TRIM56 0 0 505 505 1 1
    TRIM17 PSMA5 0 0 155 350 1 1
    TRIM17 USP11 0 0 167 227 1 1
    TRIM17 TRIM44 468 0 580 772 1 1
    TRIM17 HIST2H4A 0 0 57 167 1 1
    TRIM17 CHUK 0 0 150 210 1 1
    TRIM17 SAMHD1 0 0 155 173 1 1
    TRIM17 ZNF790 0 0 261 288 1 1
    TRIM17 HDAC1 0 0 162 197 1 2
    TRIM17 RNF150 0 0 164 205 1 1
    TRIM17 HIST3H3 0 0 99 194 1 1
    TRIM17 PGM3 0 0 297 313 1 1
    TRIM17 UBE2L6 0 0 92 176 1 1
    TRIM17 RNF34 0 0 140 233 1 1
    TRIM17 NANOS1 0 0 0 156 1 1
    TRIM17 RNF122 0 0 205 255 1 1
    TRIM17 NANOS2 0 0 0 156 1 1
    TRIM17 RNF13 0 0 183 223 1 1
    TRIM17 ANKIB1 0 0 134 247 1 1
    TRIM17 PCDHA3 0 0 171 205 1 1
    TRIM17 BTRC 0 0 265 341 1 1
    TRIM17 MID2 0 0 595 294 1 1
    TRIM17 ZNF232 0 0 181 211 1 1
    TRIM17 RNF208 0 0 166 206 1 1
    TRIM17 PMAIP1 0 0 202 202 1 1
    TRIM17 RNF130 0 0 126 226 1 1
    TRIM17 RNF20 0 0 124 212 1 1
    TRIM17 SHARPIN 0 0 341 360 1 1
    TRIM17 RNF141 0 0 150 272 1 1
    TRIM17 MTERF3 0 0 122 173 1 1
    TRIM17 UBE2Q1 0 0 134 225 1 1
    TRIM17 PUM1 0 0 0 199 1 1
    TRIM17 PECR 0 0 245 261 1 1
    TRIM17 HIPK2 0 0 155 168 1 1
    TRIM17 MCL1 0 0 301 458 1 2
    TRIM17 OR52B6 0 0 268 394 1 1
    TRIM17 HECTD3 0 0 165 199 1 1
    TRIM17 CBX1 0 0 328 366 1 1
    TRIM17 PJA2 0 0 112 187 1 1
    TRIM17 ARHGDIG 0 0 113 152 1 1
    TRIM17 IKBKG 0 0 180 179 1 1
    TRIM17 RARA 0 0 298 324 1 1
    TRIM17 ZNF728 0 0 123 155 1 1
    TRIM17 SUGT1 0 0 125 206 1 1
    TRIM17 CHD3 0 0 250 282 1 1
    TRIM17 ISG15 0 0 233 269 1 1
    TRIM17 MYOZ1 0 0 142 158 1 1
    TRIM17 TRAT1 0 0 865 865 1 1
    TRIM17 FMN1 0 0 0 167 1 1
    TRIM17 BTBD17 0 0 187 409 1 1
    TRIM17 ATM 0 0 152 151 1 1
    TRIM17 TRIM63 0 0 310 152 1 1
    TRIM17 RET 0 0 134 167 1 1
    TRIM17 NFKBIA 0 0 97 175 1 1
    TRIM17 RNF157 0 0 167 226 1 1
    TRIM17 WSB2 0 0 125 231 1 1
    TRIM17 HIST1H4A 0 0 57 167 1 1
    TRIM17 RCHY1 0 0 103 164 1 1
    TRIM17 HECW2 0 0 95 209 1 1
    TRIM17 GABARAP 0 0 72 185 1 2
    TRIM17 SNIP1 0 0 194 211 1 1
    TRIM17 DET1 0 0 102 196 1 1
    TRIM17 TRAF7 0 0 122 188 1 1
    TRIM17 USP13 0 0 154 212 1 1
    TRIM17 ZNF197 0 0 212 241 1 1
    TRIM17 MARCH1 0 0 123 166 1 1
    TRIM17 MYCBP2 0 0 59 157 1 1
    TRIM17 RUNX1 0 0 385 394 1 1
    TRIM17 PHOX2B 0 0 170 251 1 1
    TRIM17 RHEB 0 0 307 317 1 2
    TRIM17 SH3BGR 0 0 120 254 1 1
    TRIM17 HIST2H4B 0 0 57 167 1 1
    TRIM17 UBE2I 0 0 603 614 1 1
    TRIM17 ZNF101 0 0 57 154 1 1
    TRIM17 RNF170 0 0 152 180 1 1
    TRIM17 RFWD2 0 0 123 198 1 1
    TRIM17 KAT2B 0 0 81 150 1 1
    TRIM17 CCNB1IP1 0 0 94 187 1 1
    TRIM17 RNF41 0 0 408 408 1 1
    TRIM17 HIST1H4H 0 0 57 167 1 1
    TRIM17 C10orf10 0 0 100 331 1 1
    TRIM17 BCL2A1 270 0 73 305 1 1
    TRIM17 SHPRH 0 0 74 200 1 1
    TRIM17 TRIM74 0 0 293 156 1 1
    TRIM17 IGBP1 0 0 137 151 1 1
    TRIM17 TANK 0 0 143 196 1 1
    TRIM17 EYA1 0 0 472 472 1 1
    TRIM17 NHLRC1 0 0 181 210 1 1
    TRIM17 RNF25 0 0 112 205 1 1
    TRIM17 RNF185 0 0 194 200 1 1
    TRIM17 UBE2W 108 0 181 258 1 1
    TRIM17 SLC6A9 0 0 0 197 1 1
    TRIM17 WSB1 0 0 106 180 1 1
    TRIM17 FBXL14 0 0 97 192 1 1
    TRIM17 ZKSCAN7 0 0 342 366 1 1
    TRIM17 HIST1H4C 0 0 57 167 1 1
    TRIM17 RNF144A 0 0 146 261 1 1
    TRIM17 ACKR1 0 0 54 175 1 1
    TRIM17 RNF121 0 0 166 223 1 1
    TRIM17 PPIAL4B 0 0 0 310 1 1
    TRIM17 RNF133 0 0 201 242 1 1
    TRIM17 SUMO1 0 0 392 405 1 1
    TRIM17 TPM3 0 0 0 169 1 1
    TRIM17 UBA7 0 0 108 150 1 1
    TRIM17 CRYBB3 0 0 90 168 1 1
    TRIM17 AGO3 0 0 0 169 1 1
    TRIM17 SSRP1 0 0 0 196 1 1
    TRIM17 TCEB2 0 0 138 208 1 1
    TRIM17 THOC2 0 0 107 364 1 1
    TRIM17 UBQLN1 0 0 134 194 1 2
    TRIM17 NFATC4 0 0 436 436 1 1
    TRIM17 PHF20 0 0 166 197 1 1
    TRIM17 RNF103 0 0 147 246 1 1
    TRIM17 TRIM28 270 0 621 711 1 2
    TRIM17 RNF112 0 0 74 181 1 1
    TRIM17 TXNDC9 0 0 0 154 1 1
    TRIM17 RNF139 0 0 108 190 1 1
    TRIM17 TERF2IP 0 0 165 165 1 1
    TRIM17 USP12 0 0 96 202 1 1
    TRIM17 BBOX1 0 0 870 870 1 1
    TRIM17 MPHOSPH8 0 0 0 157 1 1
    TRIM17 CUTA 0 0 53 234 1 1
    TRIM17 TRIM29 0 0 405 414 1 1
    TRIM17 ZWINT 270 0 261 449 1 1
    TRIM17 USP7 0 0 317 337 1 1
    TRIM17 UBR1 0 0 201 362 1 1
    TRIM17 HIST1H4D 0 0 57 167 1 1
    TRIM17 TBK1 0 0 108 155 1 2
    TRIM17 MARCH5 0 0 161 185 1 1
    TRIM17 SKP1 0 0 218 218 1 1
    TRIM17 SP100 0 0 420 420 1 1
    TRIM17 MUL1 0 0 165 180 1 2
    TRIM17 ZMYM2 0 0 306 316 1 1
    TRIM17 ZNF439 0 0 96 153 1 1
    TRIM17 CUL4A 0 0 94 151 1 1
    TRIM17 DCDC2B 0 0 0 152 1 1
    TRIM17 KIFC2 0 0 0 211 1 1
    TRIM17 SIM2 0 0 108 207 1 1
    TRIM17 MKRN2 0 0 166 239 1 1
    TRIM17 UBE2E1 192 0 409 515 1 1
    TRIM17 NLRX1 0 0 134 166 1 1
    TRIM17 DEF8 0 0 136 158 1 1
    TRIM17 ZNF746 0 0 130 162 1 1
    TRIM17 PJA1 0 0 141 282 1 1
    TRIM17 HNRNPH1 270 0 0 270 1 1
    TRIM17 PPIAL4C 0 0 0 310 1 1
    TRIM17 MID1 0 0 572 277 1 1
    TRIM17 TINF2 0 0 245 284 1 1
    TRIM17 PCGF6 0 0 87 197 1 1
    TRIM17 UBAP1 0 0 97 192 1 1
    TRIM17 TRIM31 0 0 468 181 1 1
    TRIM17 ARIH1 0 0 96 189 1 1
    TRIM17 UTP14C 0 0 0 155 1 1
    TRIM17 CPSF6 0 0 140 229 1 1
    TRIM17 PUM2 0 0 0 199 1 1
    TRIM17 SERINC3 0 0 171 171 1 1
    TRIM17 PRAM1 0 0 74 274 1 1
    TRIM17 RNF113B 0 0 163 163 1 1
    TRIM17 TRIM6 0 0 458 154 1 1
    TRIM17 ZSWIM2 0 0 244 402 1 1
    TRIM17 TPP1 0 0 162 177 1 1
    TRIM17 AMFR 0 0 135 214 1 1
    TRIM17 TRIM55 0 0 390 210 1 1
    TRIM17 USP29 0 0 86 177 1 1
    TRIM17 DICER1 0 0 0 171 1 1
    TRIM17 ZNF524 0 0 81 158 1 1
    TRIM17 NACC1 0 0 108 166 1 1
    TRIM17 PPIAL4G 0 0 0 310 1 1
    TRIM17 TRAF6 192 0 195 321 1 2
    TRIM17 MARCH3 0 0 146 251 1 1
    TRIM17 RNF17 0 0 107 201 1 1
    TRIM17 NANOS3 0 0 46 161 1 1
    TRIM17 NUP133 0 0 73 236 1 1
    TRIM17 TPM2 0 0 0 169 1 1
    TRIM17 MARCH2 0 0 112 171 1 1
    TRIM17 PAX6 0 0 156 180 1 1
    TRIM17 LONRF3 0 0 138 222 1 1
    TRIM17 FBXO9 0 0 0 151 1 1
    TRIM17 CDK2AP1 0 0 0 210 1 1
    TRIM17 ANKRD11 0 0 81 174 1 1
    TRIM17 DUT 0 0 66 150 1 1
    TRIM17 RNF123 0 0 136 225 1 1
    TRIM17 GGH 0 0 215 215 1 1
    TRIM17 UBOX5 0 0 196 197 1 1
    TRIM17 LGALS8 270 0 60 284 1 1
    TRIM17 EP300 0 0 125 169 1 1
    TRIM17 TRIM41 308 0 359 358 1 1
    TRIM17 CUL1 0 0 433 455 1 1
    TRIM17 RNF44 0 0 164 257 1 1
    TRIM17 TRIM8 0 0 536 256 1 1
    TRIM17 PHF7 0 0 206 327 1 1
    TRIM17 DPCR1 0 0 174 173 1 1
    TRIM17 MKRN1 0 0 134 193 1 1
    TRIM17 UBR5 0 0 90 158 1 1
    TRIM17 GNGT1 0 0 95 237 1 1
    TRIM17 RNF111 0 0 172 223 1 1
    TRIM17 STMN4 0 0 74 161 1 1
    TRIM17 HUWE1 0 0 287 316 1 1
    TRIM17 SENP5 0 0 155 154 1 1
    TRIM17 TRIM6-TRIM34 0 0 456 197 1 1
    TRIM17 CDC26 0 0 96 194 1 1
    TRIM17 RNF10 0 0 124 233 1 1
    TRIM17 NUP153 0 0 123 201 1 1
    TRIM17 MAP3K7 0 0 70 183 1 1
    TRIM17 TRIM15 0 0 406 151 1 1
    TRIM17 CUL2 0 0 96 171 1 1
    TRIM17 ANKS1A 0 0 123 317 1 1
    TRIM17 USP54 0 0 158 302 1 1
    TRIM17 RPL36 0 0 0 161 1 1
    TRIM17 NEDD8 0 0 181 235 1 1
    TRIM17 MDM2 0 0 216 216 1 1
    TRIM17 TP53 0 0 284 295 1 2
    TRIM17 TRIM16 0 0 508 247 1 2
    TRIM17 TNPO3 0 0 142 231 1 1
    TRIM17 CDKN2D 0 0 113 156 1 1
    TRIM17 ANKS1B 0 0 0 253 1 1
    TRIM17 THOC3 0 0 112 308 1 1
    TRIM17 MARCH7 0 0 144 251 1 1
    TRIM17 ZNRF4 0 0 184 235 1 1
    TRIM17 ZNF501 0 0 310 335 1 1
    TRIM17 PBK 0 0 0 156 1 1
    TRIM17 OBSCN 0 0 0 158 1 1
    TRIM17 USP15 192 0 202 366 1 1
    TRIM17 PIM1 0 0 0 205 1 1
    TRIM17 ZFP57 0 0 150 200 1 1
    TRIM17 ZNF268 0 0 183 213 1 1
    TRIM17 TRIM33 0 0 538 538 1 1
    TRIM17 PDE6H 0 0 96 181 1 1
    TRIM17 CBX5 0 0 307 346 1 1
    TRIM17 IFNA1 0 0 181 181 1 1
    TRIM17 UBE2H 108 0 150 303 1 1
    TRIM17 RNF125 0 0 174 204 1 1
    TRIM17 CA7 0 0 0 164 1 1
    TRIM17 HIST4H4 0 0 57 167 1 1
    TRIM17 GAPDH 0 0 162 194 1 2
    TRIM17 PML 0 0 635 641 1 1
    TRIM17 TRIM25 0 0 648 309 1 1
    TRIM17 CAMSAP3 0 0 117 175 1 1
    TRIM17 MAP1LC3B2 0 0 0 157 1 2
    TRIM17 USP9X 0 0 325 445 1 1
    TRIM17 ZNF645 0 0 161 218 1 1
    TRIM17 WWP1 0 0 107 168 1 1
    TRIM17 TRIM9 0 0 641 654 1 1
    TRIM17 TERF2 0 0 181 228 1 1
    TRIM17 RUNX1T1 0 0 321 321 1 1
    TRIM17 UBE2D3 294 0 128 374 1 1
    TRIM17 TRIM71 0 0 470 470 1 1
    TRIM17 ZNF575 0 0 248 369 1 1
    TRIM17 USP42 0 0 134 198 1 1
    TRIM17 MED15 0 0 219 232 1 1
    TRIM17 TRIM59 0 0 469 218 1 1
    TRIM17 RNF138 0 0 123 163 1 1
    TRIM17 HIST1H4F 0 0 57 167 1 1
    TRIM17 BAZ1A 0 0 66 192 1 1
    TRIM17 RNF24 0 0 134 199 1 1
    TRIM17 DLK2 0 0 107 199 1 1
    TRIM17 RNF145 0 0 150 168 1 1
    TRIM17 ATXN1 0 0 139 174 1 1
    TRIM17 ZNF74 0 0 91 200 1 1
    TRIM17 SUMO2 0 0 330 344 1 1
    TRIM17 TRIM49 0 0 727 215 1 1
    TRIM17 PPIAL4H 0 0 0 310 1 1
    TRIM17 NEDD4 0 0 173 192 1 2
    TRIM17 MAGEC2 0 0 444 444 1 1
    TRIM17 CASP3 0 0 128 158 1 2
    TRIM17 SMURF1 0 0 107 151 1 1
    TRIM17 FBXO27 0 0 134 257 1 1
    TRIM17 PLA2G6 0 0 0 200 1 1
    TRIM17 HDAC9 0 0 119 157 1 1
    TRIM17 UBE2V1 0 0 175 189 1 1
    TRIM17 RNF152 0 0 142 231 1 1
    TRIM17 MARCH9 0 0 142 249 1 1
    TRIM17 RNF151 0 0 180 245 1 1
    TRIM17 DTX3 0 0 97 219 1 1
    TRIM17 ADAM29 0 0 98 154 1 1
    TRIM17 TRIM22 0 0 601 184 1 1
    TRIM17 ZW10 0 0 138 228 1 1
    TRIM17 UBA2 0 0 116 191 1 1
    TRIM17 FBXO17 0 0 122 242 1 1
    TRIM17 GPX8 0 0 81 197 1 1
    TRIM17 PPIAL4D 0 0 0 310 1 1
    TRIM17 CEBPB 0 0 188 188 1 1
    TRIM17 NPAS4 0 0 61 159 1 1
    TRIM17 ZNRF2 0 0 125 229 1 1
    TRIM17 NUP155 0 0 0 162 1 1
    TRIM17 ZNF598 0 0 123 219 1 1
    TRIM17 DTX2 0 0 134 225 1 1
    TRIM17 ACADSB 0 0 75 150 1 1
    TRIM17 LNX2 0 0 108 199 1 1
    TRIM17 ENSG00000257767 0 0 0 182 1 1
    TRIM17 HIST1H4G 0 0 0 153 1 1
    TRIM17 PIAS1 0 0 217 237 1 1
    TRIM17 ENSG00000256825 0 0 193 223 1 1
    TRIM17 MEX3C 0 0 139 244 1 1
    TRIM17 CMYA5 0 0 95 307 1 1
    TRIM17 BECN1 0 0 563 568 1 2
    TRIM17 FBXL19 0 0 0 239 1 1
    TRIM17 CCT6B 0 0 140 342 1 1
    TRIM17 USP20 0 0 113 194 1 1
    TRIM17 REM2 0 0 0 201 1 1
    TRIM17 ZNF362 0 0 218 247 1 1
    TRIM17 RNF114 0 0 150 237 1 1
    TRIM17 TRIM39 675 0 501 696 1 1
    TRIM17 RNF146 0 0 99 161 1 1
    TRIM17 PDZRN3 0 0 94 205 1 1
    TRIM17 IFT80 0 0 82 238 1 1
    TRIM17 IFNB1 0 0 243 242 1 1
    TRIM17 UBE2D2 485 0 376 673 1 1
    TRIM17 SENP3 0 0 228 256 1 1
    TRIM17 UBQLN2 0 0 122 164 1 2
    TRIM17 UBE3B 0 0 107 218 1 1
    TRIM17 ANKRD24 0 0 0 155 1 1
    TRIM17 TMEM79 0 0 142 174 1 1
    TRIM17 MAP1LC3B 0 0 46 162 1 2
    TRIM17 UBC 270 0 46 308 1 1
    TRIM17 AREL1 0 0 206 263 1 1
    TRIM17 DLG4 0 0 0 158 1 1
    TRIM17 TRIM46 0 0 577 298 1 1
    TRIM17 TRIM45 0 0 320 334 1 1
    TRIM17 ZFPL1 0 0 162 214 1 1
    TRIM17 UBE2S 0 0 203 223 1 1
    TRIM17 RNF128 0 0 146 227 1 1
    TRIM17 TRIM32 0 0 635 635 1 1
    TRIM17 PRDM9 0 0 165 196 1 1
    TRIM17 ZSCAN12 0 0 53 165 1 1
    TRIM17 RNF26 0 0 218 253 1 1
    TRIM17 TRIM54 0 0 459 227 1 1
    TRIM17 ELL2 0 0 67 270 1 1
    TRIM17 CTSG 0 0 306 316 1 1
    TRIM17 UBR3 0 0 193 260 1 1
    TRIM17 ZNF284 0 0 0 169 1 1
    TRIM17 HIST1H4K 0 0 57 167 1 1
    TRIM17 CHFR 0 0 137 213 1 1
    TRIM17 RFWD3 0 0 127 201 1 1
    TRIM17 TRIM67 0 0 726 736 1 1
    TRIM17 BST2 0 0 204 240 1 1
    TRIM17 TERF1 0 0 240 244 1 1
    TRIM17 AGO1 0 0 0 169 1 1
    TRIM17 TRIM47 0 0 398 215 1 1
    TRIM17 RNF14 0 0 95 166 1 1
    TRIM17 ZFYVE9 0 0 351 369 1 1
    TRIM17 CCT6A 0 0 0 186 1 1
    TRIM17 BARD1 0 0 141 212 1 1
    TRIM17 TRIM42 0 0 212 295 1 1
    TRIM17 ACOT13 0 0 98 192 1 1
    TRIM17 DCST1 0 0 155 222 1 1
    TRIM17 RNF186 0 0 161 161 1 1
    TRIM17 HDAC7 0 0 150 186 1 1
    TRIM17 ZNF569 0 0 302 327 1 1
    TRIM17 HIST1H4B 0 0 57 167 1 1
    TRIM17 CBL 0 0 184 206 1 1
    TRIM17 UBL4A 0 0 119 247 1 1
    TRIM17 CLASRP 0 0 81 268 1 1
    TRIM17 IRF7 0 0 214 244 1 1
    TRIM17 RNF166 0 0 164 216 1 1
    TRIM17 FAT2 0 0 0 153 1 1
    TRIM17 USP26 0 0 123 267 1 1
    TRIM17 CSNK2A1 0 0 122 190 1 1
    TRIM17 HECW1 0 0 150 219 1 1
    TRIM17 FKBP1C 0 0 266 295 1 1
    TRIM17 UBL3 0 0 148 235 1 1
    TRIM17 ARIH2 0 0 124 224 1 1
    TRIM17 ITCH 0 0 150 203 1 1
    TRIM17 RNF4 0 0 370 383 1 1
    TRIM17 SIN3A 0 0 292 308 1 1
    TRIM17 CHRNA1 0 0 66 182 1 1
    TRIM17 MARCH8 0 0 141 251 1 1
    TRIM17 PPP2R4 0 0 306 306 1 1
    TRIM17 UBR2 0 0 96 188 1 1
    TRIM17 MARCH10 0 0 180 213 1 1
    TRIM17 UBE3A 0 0 230 248 1 1
    TRIM17 MARCH6 0 0 108 218 1 1
    TRIM17 ZNF10 0 0 321 346 1 1
    TRIM17 CD4 0 0 120 172 1 1
    TRIM17 GUCA1B 0 0 90 252 1 1
    TRIM17 ZNF324B 0 0 96 208 1 1
    TRIM17 IRF3 0 0 293 304 1 1
    TRIM17 TRIM2 0 0 370 187 1 1
    TRIM17 TRIM36 0 0 391 390 1 1
    TRIM17 NSMCE1 0 0 125 222 1 1
    TRIM17 FBXL17 0 0 108 215 1 1
    TRIM17 PCDH8 0 0 124 247 1 1
    TRIM17 SUPT16H 0 0 0 281 1 1
    TRIM17 ZNF136 0 0 150 181 1 1
    TRIM17 SMC4 0 0 60 154 1 1
    TRIM17 CA10 0 0 0 165 1 1
    TRIM17 RNF7 0 0 167 189 1 1
    TRIM17 BTBD2 0 0 166 190 1 1
    TRIM17 LGALS3 270 0 0 270 1 1
    TRIM17 TRIM52 0 0 400 159 1 1
    TRIM17 UTP14A 0 0 0 155 1 1
    TRIM17 WWP2 0 0 94 156 1 1
    TRIM17 TRIML2 0 0 203 242 1 1
    TRIM17 USP2 0 0 113 174 1 1
    TRIM17 BRAP 0 0 0 250 1 1
    TRIM17 G2E3 0 0 113 205 1 1
    TRIM17 USP8 0 0 161 183 1 1
    TRIM17 SERTAD4 0 0 204 389 1 1
    TRIM17 GHITM 0 0 81 282 1 1
    TRIM17 RBX1 0 0 167 197 1 1
    TRIM17 TRIM50 0 0 325 164 1 1
    TRIM17 ZFYVE1 0 0 438 462 1 2
    TRIM17 CDA 0 0 112 159 1 1
    TRIM17 MLF1 178 0 0 177 1 1
    TRIM17 ZNF350 0 0 208 237 1 1
    TRIM17 TRIM14 0 0 235 160 1 1
    TRIM17 RNF167 0 0 205 234 1 1
    TRIM17 PIAS4 0 0 146 168 1 1
    TRIM17 SETDB1 0 0 421 449 1 1
    TRIM17 TMTC1 0 0 72 188 1 1
    TRIM17 FBXW7 0 0 216 298 1 1
    TRIM17 RGPD2 0 0 218 263 1 1
    TRIM17 CHODL 0 0 0 202 1 1
    TRIM17 DPF1 0 0 81 170 1 1
    TRIM17 YIPF2 0 0 181 181 1 1
    TRIM17 RNF5 0 0 245 251 1 1
    TRIM17 HIST1H4J 0 0 57 167 1 1
    TRIM17 TRIM73 0 0 382 180 1 1
    TRIM17 ACTB 0 0 181 213 1 1
    TRIM17 TMLHE 0 0 720 793 1 1
    TRIM17 KCNRG 0 0 606 606 1 1
    TRIM17 TPM1 0 0 0 169 1 1
    TRIM17 UBE2N 270 0 266 455 1 1
    TRIM17 GABARAPL1 0 0 112 220 1 2
    TRIM17 ZNF324 0 0 0 156 1 1
    TRIM17 DTX4 0 0 140 227 1 1
    TRIM17 ZNF224 0 0 107 202 1 1
    TRIM17 MEX3B 0 0 92 209 1 1
    TRIM17 PNRC1 0 0 125 185 1 1
    TRIM17 USP4 0 0 181 228 1 1
    TRIM17 MIB2 0 0 0 167 1 1
    TRIM17 TTC3 0 0 82 169 1 1
    TRIM17 RNF182 0 0 166 165 1 1
    TRIM17 FBXO36 0 0 71 183 1 1
    TRIM17 UHRF2 0 0 108 175 1 1
    TRIM17 TRIM3 0 0 539 300 1 1
    TRIM17 SAE1 0 0 142 194 1 1
    TRIM17 MNAT1 192 0 0 210 1 1
    TRIM17 SH3RF2 0 0 201 243 1 1
    TRIM17 ZNF225 0 0 204 233 1 1
    TRIM17 ZNF623 0 0 112 176 1 1
    TRIM17 DEDD 0 0 74 168 1 1
    TRIM17 UBE3C 0 0 109 229 1 1
    TRIM17 ZNF629 0 0 310 335 1 1
    TRIM17 MAN2A1 0 0 112 173 1 1
    TRIM17 ITPR3 0 0 327 327 1 1
    TRIM17 PHF13 0 0 293 319 1 1
    TRIM17 MEX3D 0 0 150 308 1 1
    TRIM17 BCL2L11 0 0 136 214 1 1
    TRIM17 RNF148 0 0 188 243 1 1
    TRIM17 PSMD4 0 0 75 247 1 1
    TRIM17 TRIM5 0 0 815 215 1 2
    TRIM17 ACAD10 0 0 0 153 1 1
    TRIM17 APOBEC3F 0 0 171 189 1 1
    TRIM17 TRIM35 0 0 459 176 1 1
    TRIM17 TMEM196 0 0 202 489 1 1
    TRIM17 RNF19A 0 0 145 169 1 1
    TRIM17 ITPR1 0 0 294 315 1 2
    TRIM17 RNF144B 0 0 195 251 1 1
    TRIM17 TRIM16L 0 0 342 342 1 1
    TRIM17 PAQR6 0 0 0 151 1 1
    TRIM17 MAGEA3 0 0 177 177 1 2
    TRIM17 ADAM11 0 0 0 155 1 1
    TRIM17 USP24 0 0 139 285 1 1
    TRIM17 SH3RF1 0 0 108 201 1 1
    TRIM17 SMARCB1 0 0 330 341 1 1
    TRIM17 MX2 0 0 122 173 1 1
    TRIM17 HIST2H3PS2 0 0 161 250 1 1
    TRIM17 IFIH1 0 0 134 174 1 1
    TRIM17 CNOT4 0 0 74 308 1 1
    TRIM17 CUL5 0 0 167 222 1 1
    TRIM17 MAP1LC3C 0 0 45 161 1 2
    TRIM17 PPIAL4F 0 0 0 310 1 1
    TRIM17 CCL4 0 0 368 368 1 1
    TRIM17 MAVS 0 0 232 244 1 1
    TRIM17 RNF31 0 0 241 257 1 1
    TRIM17 LGALS4 0 0 161 161 1 1
    TRIM17 MTERF1 0 0 182 227 1 1
    TRIM17 TPM4 0 0 0 169 1 1
    TRIM17 ZNF763 0 0 310 335 1 1
    TRIM17 DDX58 0 0 310 341 1 1
    TRIM17 HIST1H4E 0 0 57 167 1 1
    TRIM17 UBE2D4 108 0 94 196 1 1
    TRIM17 SEC31B 0 0 150 217 1 1
    TRIM17 NAIF1 0 0 63 159 1 1
    TRIM17 ENSG00000279782 0 0 0 310 1 1
    TRIM17 HERC4 0 0 103 214 1 1
    TRIM17 ZNF436 0 0 321 359 1 1
    TRIM17 KAT2A 0 0 82 182 1 1
    TRIM17 UBE2U 0 0 57 161 1 1
    TRIM17 RC3H1 0 0 120 207 1 1
    TRIM17 UBAP2 0 0 122 219 1 1
    TRIM17 DCLK1 0 0 0 171 1 1
    TRIM17 RNF207 0 0 260 260 1 1
    TRIM17 TRIM62 0 0 467 197 1 1
    TRIM17 RLIM 0 0 81 170 1 1
    TRIM17 AGO2 0 0 0 169 1 1
    TRIM17 RHPN1 0 0 0 180 1 1
    TRIM17 TRIM23 0 0 421 433 1 1
    TRIM17 HGS 129 0 0 166 1 2
    TRIM17 ZFYVE19 0 0 138 301 1 1
    TRIM17 PIN1 0 0 160 261 1 1
    TRIM17 ZFAND4 0 0 146 293 1 1
    TRIM17 LTN1 0 0 94 189 1 1
    TRIM17 RNF126 0 0 112 215 1 1
    TRIM17 EDARADD 0 0 0 156 1 1
    TRIM17 ZNF44 0 0 310 335 1 1
    TRIM17 TRIM40 0 0 249 152 1 1
    TRIM17 RNF149 0 0 144 181 1 1
    TRIM17 SIAH2 0 0 137 190 1 1
    TRIM17 RNF115 0 0 146 195 1 1
    TRIM17 BRSK1 0 0 0 157 1 1
    TRIM17 ZNF248 0 0 124 156 1 1
    TRIM17 HIST1H4I 0 0 57 167 1 1
    TRIM17 VPS53 0 0 96 308 1 1
    TRIM17 TRIM24 0 0 596 596 1 1
    TRIM17 RNF40 0 0 81 175 1 1
    TRIM17 UNK 0 0 74 151 1 1
    TRIM17 FKBP7 0 0 261 291 1 1
    TRIM17 RSG1 0 0 0 156 1 1
    TRIM17 RBCK1 0 0 465 480 1 1
    TRIM17 UBE2K 0 0 108 219 1 1
    TRIM17 RNF214 0 0 166 165 1 1
    TRIM17 SLC6A7 0 0 100 417 1 1
    TRIM17 TAX1BP1 0 0 145 177 1 2
    TRIM17 AGO4 0 0 0 169 1 1
    TRIM17 SHANK1 0 0 134 231 1 1
    TRIM17 UBD 0 0 120 162 1 1
    TRIM17 RUFY1 0 0 96 207 1 1
    TRIM17 UBA1 0 0 137 189 1 1
    TRIM17 HIST1H4L 0 0 57 167 1 1
    TRIM17 YJEFN3 0 0 0 151 1 1
    TRIM17 DZIP3 0 0 95 196 1 1
    TRIM17 RUVBL2 0 0 81 178 1 1
    TRIM17 DHX33 0 0 97 152 1 1
    TRIM17 UBE2D1 485 0 289 635 1 1
    TRIM17 LONRF1 0 0 129 164 1 1
    TRIM17 TAB2 0 0 279 368 1 1
    TRIM17 ZNF274 0 0 261 288 1 1
    TRIM17 CAPN3 0 0 218 255 1 1
    TRIM17 ACOT11 0 0 104 160 1 1
    TRIM17 PPIG 0 0 217 226 1 1
    TRIM17 MYC 0 0 212 242 1 2
    TRIM17 ATRX 0 0 145 197 1 1
    TRIM17 PHRF1 0 0 161 181 1 1
    TRIM17 GABARAPL2 0 0 108 216 1 2
    TRIM17 UBE2V2 0 0 207 221 1 1
    TRIM17 FSD2 0 0 206 206 1 1
    TRIM17 ZSCAN21 0 0 162 204 1 1
    TRIM17 RNF6 0 0 96 196 1 1
    TRIM17 DERA 0 0 123 183 1 1
    TRIM17 UHRF1 0 0 167 177 1 1
    TRIM17 LONRF2 0 0 134 203 1 1
    TRIM17 TAB3 0 0 212 275 1 2
    TRIM17 ZNF251 0 0 150 181 1 1
    TRIM17 ABAT 0 0 0 165 1 1
    TRIM17 OR52H1 0 0 252 549 1 1
    TRIM17 SIAH1 0 0 146 188 1 1
    TRIM17 RANBP2 0 0 266 350 1 1
    TRIM17 MAPKBP1 0 0 108 243 1 1
    TRIM17 AP3B1 0 0 82 178 1 1
    TRIM17 LRSAM1 192 0 82 316 1 2
    TRIM17 ACTN4 0 0 356 368 1 1
    TRIM17 RPS6 0 0 296 296 1 1
    TRIM17 CBX3 0 0 330 368 1 1
    TRIM17 TRIM37 0 0 322 321 1 1
    TRIM17 WDSUB1 0 0 170 169 1 1
    TRIM17 NFYB 0 0 0 162 1 1
    TRIM17 PLSCR3 0 0 119 244 1 1
    TRIM17 SMARCAD1 0 0 215 215 1 1
    TRIM17 APOBEC3G 0 0 262 335 1 1
    TRIM17 MYO5A 0 0 389 406 1 1
    TRIM17 RNF169 0 0 137 156 1 1
    TRIM17 EXOC8 0 0 130 184 1 1
    TRIM17 TRIM13 0 0 499 229 1 2
    TRIM17 MAP1LC3A 0 0 46 183 1 2
    TRIM17 RNF11 0 0 187 204 1 1
    TRIM17 TRIM66 0 0 630 630 1 1
    TRIM17 KCNIP2 0 0 0 176 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0030674 Molecular Function protein-macromolecule adaptor activity enables IPI
    GO:0061630 Molecular Function ubiquitin protein ligase activity enables IBA
    GO:0004842 Molecular Function ubiquitin-protein transferase activity enables IDA
    GO:0008270 Molecular Function zinc ion binding enables IEA
    GO:0006914 Biological Process autophagy involved_in IDA
    GO:0045087 Biological Process innate immune response involved_in IBA
    GO:0051865 Biological Process protein autoubiquitination involved_in IDA
    GO:0010468 Biological Process regulation of gene expression involved_in IBA
    GO:0032880 Biological Process regulation of protein localization involved_in IMP
    GO:0005737 Cellular Component cytoplasm is_active_in IBA
    GO:0005764 Cellular Component lysosome located_in IEA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_047422088 1 mRNA transcript variant X5 NC_000001 Reference
    NM_001024940 3 mRNA transcript variant 2 NC_000001 Reference
    NM_016102 4 mRNA transcript variant 1 NC_000001 Reference
    XM_011544211 4 mRNA transcript variant X6 NC_000001 Reference
    XM_017001419 2 mRNA transcript variant X10 NC_000001 Reference
    XM_011544210 4 mRNA transcript variant X3 NC_000001 Reference
    XM_047422103 1 mRNA transcript variant X9 NC_000001 Reference
    XM_006711779 4 mRNA transcript variant X2 NC_000001 Reference
    XM_047422098 1 mRNA transcript variant X8 NC_000001 Reference
    XM_011544209 4 mRNA transcript variant X4 NC_000001 Reference
    XM_047422091 1 mRNA transcript variant X7 NC_000001 Reference
    XM_047422078 1 mRNA transcript variant X1 NC_000001 Reference
    NM_001134855 2 mRNA transcript variant 4 NC_000001 Reference