ATF4

activating transcription factor 4
General Information
Name activating transcription factor 4
Alias
  • cyclic AMP-dependent transcription factor ATF-4
  • DNA-binding protein TAXREB67
  • cAMP response element-binding protein 2
  • cAMP-dependent transcription factor ATF-4
  • cAMP-responsive element-binding protein 2
  • cyclic AMP-responsive element-binding protein 2
  • tax-responsive enhancer element B67
  • tax-responsive enhancer element-binding protein 67
Synonyms TAXREB67 CREB-2 CREB2 TXREB
Gene_family Basic leucine zipper proteins
organism Homo sapiens
entrez_id 468
location 22q13.1
transcript_count 2
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
      Stringdb Cyclic AMP-dependent transcription factor ATF-4; Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to endoplasmic reticulum (ER) stress. In concert wit [...]
      nextProt (Microbial infection) Binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ATF4 BioGRID CEBPB GeneID BioGRID Affinity Capture-MS
    ATF4 BioGRID TBL2 GeneID BioGRID Affinity Capture-RNA
    ATF4 BioGRID SOX2 GeneID BioGRID Affinity Capture-Western
    ATF4 BioGRID POU5F1 GeneID BioGRID Affinity Capture-Western
    ATF4 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western
    ATF4 BioGRID TBC1D25 GeneID BioGRID Affinity Capture-MS
    ATF4 BioGRID NFE2L2 GeneID BioGRID Affinity Capture-Western; FRET
    ATF4 BioGRID FASN GeneID BioGRID Positive Genetic
    ATF4 BioGRID LDLR GeneID BioGRID Positive Genetic
    ATF4 BioGRID KTN1 GeneID BioGRID Proximity Label-MS
    ATF4 BioGRID E6 GeneID BioGRID PCA
    ATF4 BioGRID E6 GeneID BioGRID PCA
    ATF4 BioGRID GOLGA8F GeneID BioGRID Two-hybrid
    ATF4 BioGRID NAP1L5 GeneID BioGRID Two-hybrid
    ATF4 BioGRID TARS3 GeneID BioGRID Two-hybrid
    ATF4 BioGRID JDP2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID SAPCD2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID GCC1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID TRIB3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATF4 BioGRID CEP83 GeneID BioGRID Two-hybrid
    ATF4 BioGRID CCDC106 GeneID BioGRID Two-hybrid
    ATF4 BioGRID LDOC1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID NDC80 GeneID BioGRID Two-hybrid
    ATF4 BioGRID BTRC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Protein-peptide; Two-hybrid
    ATF4 BioGRID AP1M1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID BFSP2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID TTR GeneID BioGRID Two-hybrid
    ATF4 BioGRID GPS2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID GOLGA1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID CEBPG GeneID BioGRID FRET; Two-hybrid
    ATF4 BioGRID ABRAXAS2 GeneID BioGRID Affinity Capture-Western; Co-localization
    ATF4 BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID CREBBP GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
    ATF4 BioGRID EGLN3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATF4 BioGRID EGLN2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATF4 BioGRID RPT5 GeneID BioGRID Two-hybrid
    ATF4 BioGRID MDM2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID NLGN3 GeneID BioGRID Two-hybrid
    ATF4 BioGRID DNMT3L GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID JUN GeneID BioGRID Co-localization; FRET; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID FOS GeneID BioGRID Co-localization; FRET
    ATF4 BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
    ATF4 BioGRID SHMT2 GeneID BioGRID Affinity Capture-RNA
    ATF4 BioGRID MOV10 GeneID BioGRID Affinity Capture-RNA
    ATF4 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
    ATF4 BioGRID GOLGA8EP GeneID BioGRID Two-hybrid
    ATF4 BioGRID DDIT3 GeneID BioGRID FRET; Two-hybrid
    ATF4 BioGRID NEK6 GeneID BioGRID Biochemical Activity; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID ATF2 GeneID BioGRID FRET
    ATF4 BioGRID CEBPE GeneID BioGRID Co-localization; FRET
    ATF4 BioGRID CEBPA GeneID BioGRID FRET
    ATF4 BioGRID ATF4 GeneID BioGRID FRET
    ATF4 BioGRID ATF3 GeneID BioGRID Affinity Capture-Western; FRET
    ATF4 BioGRID BATF2 GeneID BioGRID FRET
    ATF4 BioGRID CREBZF GeneID BioGRID FRET
    ATF4 BioGRID BATF3 GeneID BioGRID FRET
    ATF4 BioGRID BATF GeneID BioGRID FRET
    ATF4 BioGRID CREB3 GeneID BioGRID FRET
    ATF4 BioGRID MAFB GeneID BioGRID FRET
    ATF4 BioGRID FOSL1 GeneID BioGRID FRET
    ATF4 BioGRID NFE2 GeneID BioGRID FRET
    ATF4 BioGRID MAF GeneID BioGRID FRET
    ATF4 BioGRID TGM2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID RPS6 GeneID BioGRID Two-hybrid
    ATF4 BioGRID MAP2K7 GeneID BioGRID Two-hybrid
    ATF4 BioGRID LMNB1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID JUNB GeneID BioGRID Two-hybrid
    ATF4 BioGRID HK3 GeneID BioGRID Two-hybrid
    ATF4 BioGRID ASB7 GeneID BioGRID Two-hybrid
    ATF4 BioGRID REPS1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID HAUS7 GeneID BioGRID Two-hybrid
    ATF4 BioGRID APH1A GeneID BioGRID Two-hybrid
    ATF4 BioGRID CKAP4 GeneID BioGRID Two-hybrid
    ATF4 BioGRID MPZL2 GeneID BioGRID Two-hybrid
    ATF4 BioGRID SNAP29 GeneID BioGRID Two-hybrid
    ATF4 BioGRID NFKBIA GeneID BioGRID Two-hybrid
    ATF4 BioGRID ZNF212 GeneID BioGRID Two-hybrid
    ATF4 BioGRID SRA1 GeneID BioGRID Far Western
    ATF4 BioGRID APP GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID KAT2B GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID GTF2A1L GeneID BioGRID Two-hybrid
    ATF4 BioGRID TRIM24 GeneID BioGRID Two-hybrid
    ATF4 BioGRID ZNF226 GeneID BioGRID Two-hybrid
    ATF4 Protein POLR2C GeneID HPRD None
    ATF4 Protein GPS2 GeneID HPRD None
    ATF4 Protein CCDC106 GeneID HPRD None
    ATF4 Protein TRIB3 GeneID HPRD None
    ATF4 Protein GABBR2 GeneID HPRD None
    ATF4 Protein PTCD3 GeneID HPRD None
    ATF4 Protein CREBZF GeneID HPRD None
    ATF4 Protein DISC1 GeneID HPRD None
    ATF4 Protein DAPK3 GeneID HPRD None
    ATF4 Protein NFE2L2 GeneID HPRD None
    ATF4 Protein LDOC1 GeneID HPRD None
    ATF4 Protein TREX2 GeneID HPRD None
    ATF4 Protein GTF2F2 GeneID HPRD None
    ATF4 Protein CEBPB GeneID HPRD None
    ATF4 Protein TTR GeneID HPRD None
    ATF4 Protein JUN GeneID HPRD None
    ATF4 Protein NFE2L1 GeneID HPRD None
    ATF4 Protein CEBPG GeneID HPRD None
    ATF4 Protein DDIT3 GeneID HPRD None
    ATF4 BioGRID GABBR2 GeneID BioGRID Affinity Capture-Western
    ATF4 BioGRID GABBR1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATF4 BioGRID EIF2A GeneID BioGRID Affinity Capture-Western
    ATF4 BioGRID TBP GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID POLR2C GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    ATF4 BioGRID GTF2F2 GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID GTF2B GeneID BioGRID Reconstituted Complex
    ATF4 BioGRID Cebpb GeneID BioGRID Co-crystal Structure
    ATF4 BioGRID DISC1 GeneID BioGRID Two-hybrid
    ATF4 BioGRID PTCD3 GeneID BioGRID Two-hybrid
    ATF4 BioGRID TREX2 GeneID BioGRID Two-hybrid
    ATF4 Protein DISC1 GeneID BIND An unspecified isoform of DISC1 interacts with ATF4.
    ATF4 Protein TRIB3 GeneID BIND SKIP3 interacts with ATF4.
    ATF4 Protein DISC1 GeneID BIND DISC-1 interacts with ATF4.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    ATF4 NTRK1 0 0 141 203 1 1
    ATF4 SESN1 0 0 167 185 1 2
    ATF4 GSTA1 0 0 124 178 1 1
    ATF4 HSPA9 0 0 216 248 1 1
    ATF4 IRS1 0 0 285 284 1 1
    ATF4 SGK1 0 0 146 181 1 1
    ATF4 ZNF235 0 0 0 205 1 1
    ATF4 EGR2 0 0 150 249 1 1
    ATF4 BAD 0 0 92 191 1 1
    ATF4 RPS6KB1 0 0 393 404 1 2
    ATF4 ADRB2 0 0 141 159 1 1
    ATF4 STAC 0 0 0 156 1 1
    ATF4 KAT2B 270 0 107 330 1 1
    ATF4 STX8 0 0 501 501 1 2
    ATF4 PGR 0 0 75 159 1 1
    ATF4 CDK1 0 0 108 159 1 1
    ATF4 EIF4E 0 0 391 403 1 1
    ATF4 AHR 0 0 150 328 1 1
    ATF4 ZNF557 0 0 0 155 1 1
    ATF4 CCND1 0 0 366 366 1 1
    ATF4 SREBF2 0 0 266 282 1 1
    ATF4 APEH 0 0 231 242 1 1
    ATF4 NOS3 0 0 212 212 1 1
    ATF4 JUND 0 0 260 294 1 1
    ATF4 ZNF22 0 0 0 202 1 1
    ATF4 ATF7 0 0 218 245 1 1
    ATF4 DDIT4 0 0 350 364 1 1
    ATF4 RHEB 0 0 263 347 1 2
    ATF4 AARS 0 0 159 249 1 1
    ATF4 IFRD1 0 0 102 234 1 1
    ATF4 HPRT1 0 0 167 182 1 1
    ATF4 EXOC1 161 0 0 161 1 1
    ATF4 BAK1 0 0 161 195 1 2
    ATF4 FEM1B 0 0 60 158 1 1
    ATF4 ALPL 0 0 233 232 1 1
    ATF4 AVEN 0 0 57 160 1 1
    ATF4 EEF1E1 0 0 60 399 1 1
    ATF4 SZT2 0 0 123 155 1 1
    ATF4 LDLR 68 0 142 166 1 1
    ATF4 NDEL1 0 0 136 157 1 1
    ATF4 DNAJB2 0 0 167 254 1 1
    ATF4 ATP2A2 0 0 156 208 1 1
    ATF4 CAT 0 0 335 349 1 1
    ATF4 NDC80 407 0 64 421 1 1
    ATF4 NEK6 270 0 0 270 1 1
    ATF4 HRK 0 0 161 161 1 1
    ATF4 CANX 0 0 458 461 1 2
    ATF4 TXN 0 0 294 294 1 1
    ATF4 SMG7 0 0 156 179 1 1
    ATF4 AOX1 0 0 57 197 1 1
    ATF4 CCDC106 642 0 0 642 1 1
    ATF4 SLC1A5 0 0 195 225 1 1
    ATF4 MEF2C 0 0 125 152 1 1
    ATF4 BDNF 0 0 242 241 1 2
    ATF4 PNRC2 0 0 150 168 1 1
    ATF4 TRAP1 0 0 0 210 1 2
    ATF4 LPIN2 0 0 81 182 1 1
    ATF4 VDR 0 0 90 173 1 1
    ATF4 CASP2 0 0 232 231 1 1
    ATF4 SLC6A9 0 0 134 168 1 1
    ATF4 TNF 0 0 335 356 1 1
    ATF4 MSX1 0 0 0 347 1 1
    ATF4 RNF4 270 0 0 270 1 1
    ATF4 TIPIN 0 0 77 154 1 1
    ATF4 NBR1 0 0 181 181 1 2
    ATF4 YBX1 0 0 155 178 1 1
    ATF4 LARS 0 0 204 339 1 1
    ATF4 XDH 0 0 47 205 1 1
    ATF4 C22orf29 0 0 195 195 1 1
    ATF4 CBSL 0 0 194 194 1 1
    ATF4 SLC7A11 0 0 464 475 1 1
    ATF4 RPLP0 0 0 113 156 1 1
    ATF4 PPP1R15A 0 800 758 964 1 2
    ATF4 DDX3X 0 0 93 240 1 1
    ATF4 EEF2 0 0 242 281 1 1
    ATF4 FIS1 0 0 124 160 1 2
    ATF4 ALDH18A1 0 0 182 199 1 1
    ATF4 GLS2 0 0 194 194 1 1
    ATF4 PRDX4 0 0 134 220 1 1
    ATF4 FGF2 0 0 244 243 1 1
    ATF4 CD9 0 0 53 150 1 1
    ATF4 ABCB10 0 0 0 165 1 1
    ATF4 NFE2L3 275 0 118 333 1 1
    ATF4 BCAP31 0 0 155 154 1 1
    ATF4 RAB7A 0 0 94 158 1 2
    ATF4 SDF2L1 0 0 180 305 1 1
    ATF4 RPL7A 0 0 0 163 1 1
    ATF4 BCL2A1 0 0 90 230 1 1
    ATF4 GPNMB 0 0 117 153 1 1
    ATF4 TXNIP 0 0 272 272 1 1
    ATF4 GPS2 511 0 0 511 1 1
    ATF4 RPS6KA2 0 800 72 815 1 1
    ATF4 EDEM1 0 0 563 577 1 2
    ATF4 ATG4B 0 0 152 157 1 2
    ATF4 GCG 0 0 263 263 1 1
    ATF4 MAPK1 0 600 140 642 1 2
    ATF4 IGF1 0 0 264 264 1 1
    ATF4 APOB 0 0 137 167 1 1
    ATF4 ARNTL 0 0 96 323 1 1
    ATF4 SPESP1 0 0 211 211 1 1
    ATF4 PKM 0 0 181 195 1 1
    ATF4 GADD45A 0 0 295 323 1 1
    ATF4 CEP290 0 0 633 633 1 1
    ATF4 ATF3 699 800 632 981 1 1
    ATF4 ASPG 0 0 329 339 1 1
    ATF4 EIF4EBP1 0 0 451 482 1 1
    ATF4 MAFG 0 0 175 193 1 1
    ATF4 GPT 0 0 211 225 1 1
    ATF4 PHGDH 0 0 235 302 1 1
    ATF4 FOXE1 0 0 0 155 1 1
    ATF4 PINK1 0 0 241 440 1 2
    ATF4 BCL6 0 0 82 192 1 1
    ATF4 ZNF449 0 0 0 205 1 1
    ATF4 ENSG00000274276 0 0 193 193 1 1
    ATF4 NGF 0 0 209 215 1 1
    ATF4 PMF1-BGLAP 0 0 458 457 1 1
    ATF4 ERBB2 0 0 160 159 1 2
    ATF4 TAP1 0 0 0 165 1 1
    ATF4 DENR 0 0 177 366 1 1
    ATF4 BBC3 0 0 256 256 1 1
    ATF4 TH 0 0 270 276 1 1
    ATF4 HMGXB4 0 0 305 305 1 1
    ATF4 ZNF558 0 0 0 155 1 1
    ATF4 IGF2R 0 0 66 164 1 1
    ATF4 MAFK 0 0 194 212 1 1
    ATF4 GSTA2 0 0 108 163 1 1
    ATF4 CHST14 0 0 48 183 1 1
    ATF4 STC2 0 0 181 182 1 1
    ATF4 ATP6V1A 0 0 43 261 1 1
    ATF4 CREM 0 600 150 701 1 1
    ATF4 MEPE 0 0 218 218 1 1
    ATF4 PTHLH 0 0 186 191 1 1
    ATF4 FAS 0 0 134 152 1 2
    ATF4 DERL2 0 0 181 199 1 1
    ATF4 WDTC1 0 0 60 216 1 1
    ATF4 CD4 0 0 156 155 1 1
    ATF4 MBTPS1 0 0 465 474 1 1
    ATF4 ATP2A3 0 0 103 159 1 1
    ATF4 PRKCG 0 600 0 605 1 1
    ATF4 VCAM1 0 0 150 168 1 1
    ATF4 GARS 0 0 180 250 1 1
    ATF4 ATF1 0 800 0 834 1 1
    ATF4 CPT1A 0 0 126 186 1 1
    ATF4 AKT1 0 600 502 796 1 2
    ATF4 CAPN1 0 0 134 157 1 2
    ATF4 PPARG 0 0 391 460 1 1
    ATF4 CLPP 0 0 210 259 1 1
    ATF4 LHX2 0 0 0 159 1 1
    ATF4 DISC1 272 0 972 979 1 1
    ATF4 SLC2A12 0 0 0 163 1 1
    ATF4 ABCF3 0 0 0 189 1 1
    ATF4 NOX4 0 0 218 218 1 1
    ATF4 ASNS 0 900 607 967 1 1
    ATF4 XIAP 0 0 202 211 1 1
    ATF4 CEBPG 732 600 126 948 1 1
    ATF4 EDF1 0 0 74 196 1 1
    ATF4 PPP2R4 0 0 181 181 1 1
    ATF4 PSPH 0 0 294 342 1 1
    ATF4 RUNX2 0 0 727 730 1 1
    ATF4 LGR6 0 0 0 165 1 1
    ATF4 CREB3L4 0 800 322 858 1 1
    ATF4 ATP7A 0 0 81 221 1 1
    ATF4 SDF2 0 0 0 188 1 1
    ATF4 NARS 0 0 181 246 1 1
    ATF4 ATF6 0 0 830 904 1 2
    ATF4 CARS2 0 0 232 279 1 1
    ATF4 GSTM1 0 0 108 163 1 1
    ATF4 IKBKB 0 0 225 224 1 1
    ATF4 KLF4 0 0 167 231 1 1
    ATF4 SATB1 0 0 50 251 1 1
    ATF4 TOMM20 0 0 107 220 1 1
    ATF4 YY1 0 0 170 182 1 1
    ATF4 ATF6B 0 800 193 862 1 1
    ATF4 EIF2S1 0 900 805 984 1 2
    ATF4 CHST8 0 0 0 177 1 1
    ATF4 HIAT1 0 0 0 190 1 1
    ATF4 IARS 0 0 180 248 1 1
    ATF4 MITF 0 0 145 151 1 1
    ATF4 RRAGA 0 0 174 175 1 2
    ATF4 PRKD3 0 600 0 600 1 1
    ATF4 HMOX1 0 0 606 606 1 2
    ATF4 PRKD2 0 600 0 600 1 1
    ATF4 LDOC1 303 0 0 303 1 1
    ATF4 DNMT3L 270 0 0 270 1 1
    ATF4 TRUB2 0 0 67 272 1 1
    ATF4 CAMK1G 0 600 71 658 1 1
    ATF4 GTF2B 270 0 427 564 1 1
    ATF4 DIO2 0 0 144 177 1 1
    ATF4 TXLNA 0 0 357 357 1 1
    ATF4 PRKCD 0 0 159 158 1 2
    ATF4 CDKN1B 0 0 150 188 1 2
    ATF4 SPPL3 0 0 0 157 1 1
    ATF4 GLUL 0 0 136 154 1 1
    ATF4 BNIP3L 0 0 205 205 1 2
    ATF4 MSX2 0 0 150 555 1 1
    ATF4 TSC2 0 0 321 321 1 2
    ATF4 VDAC1 0 0 217 244 1 2
    ATF4 GADD45G 0 0 131 150 1 1
    ATF4 SRC 0 0 150 168 1 1
    ATF4 SCD 0 0 218 218 1 1
    ATF4 ZNF181 0 0 0 156 1 1
    ATF4 ENSG00000250264 0 0 0 165 1 1
    ATF4 WARS2 0 0 202 202 1 1
    ATF4 CRY1 0 0 134 166 1 1
    ATF4 CREB5 0 800 170 841 1 1
    ATF4 MCU 0 0 128 150 1 1
    ATF4 DGAT2 0 0 155 154 1 1
    ATF4 BGLAP 0 0 519 519 1 1
    ATF4 TNFSF11 0 0 378 379 1 1
    ATF4 APOE 270 0 233 416 1 1
    ATF4 VDAC3 0 0 137 325 1 1
    ATF4 OXT 0 0 144 162 1 1
    ATF4 SLC2A4 0 0 181 181 1 1
    ATF4 FOXO3 0 0 324 351 1 2
    ATF4 EIF2AK3 0 800 779 957 1 2
    ATF4 ZNF180 0 0 0 210 1 1
    ATF4 HNF4A 0 0 125 152 1 1
    ATF4 ACLY 0 0 146 185 1 1
    ATF4 SRXN1 0 0 181 181 1 1
    ATF4 JDP2 249 0 131 343 1 1
    ATF4 CORO1A 0 0 0 224 1 1
    ATF4 HARS2 0 0 155 228 1 1
    ATF4 CAMK2D 0 600 0 607 1 1
    ATF4 DNAJB1 0 0 244 243 1 2
    ATF4 ATG3 0 0 203 217 1 2
    ATF4 DNAJB11 0 0 218 218 1 1
    ATF4 VHL 0 0 162 161 1 1
    ATF4 TASP1 0 0 0 252 1 1
    ATF4 FBXW11 683 0 0 683 1 1
    ATF4 TBC1D7 0 0 165 165 1 2
    ATF4 CEBPB 474 800 606 976 1 1
    ATF4 TXNRD1 0 0 270 270 1 1
    ATF4 ATG16L1 0 0 232 231 1 2
    ATF4 DBP 0 0 0 278 1 1
    ATF4 PDIA4 0 0 424 437 1 1
    ATF4 GOLGA1 271 0 0 271 1 1
    ATF4 COPS4 0 0 51 151 1 1
    ATF4 ERO1LB 0 0 293 339 1 1
    ATF4 GSK3B 0 800 214 842 1 2
    ATF4 TTR 671 0 48 684 1 2
    ATF4 CREG1 0 0 0 210 1 1
    ATF4 CASP4 0 0 407 444 1 2
    ATF4 CDKN2A 0 0 160 159 1 2
    ATF4 MRPL54 0 0 95 234 1 1
    ATF4 KLF2 0 0 112 180 1 1
    ATF4 ANGPTL3 0 0 81 176 1 1
    ATF4 CUL3 0 0 156 156 1 1
    ATF4 ZNF302 0 0 0 156 1 1
    ATF4 DUSP2 0 0 144 183 1 1
    ATF4 TNFRSF10B 0 0 393 399 1 1
    ATF4 VPS13A 0 0 75 217 1 1
    ATF4 SLC1A1 0 0 89 168 1 1
    ATF4 DLX3 0 0 206 221 1 1
    ATF4 STK17B 0 0 0 167 1 1
    ATF4 ATG12 0 0 326 338 1 2
    ATF4 PHACTR2 0 0 60 222 1 1
    ATF4 IHH 0 0 219 219 1 1
    ATF4 CYBB 0 0 183 183 1 1
    ATF4 HARS 0 0 150 240 1 1
    ATF4 GOLGA8F 250 0 0 250 1 1
    ATF4 CEBPZ 0 0 155 165 1 1
    ATF4 PPIC 0 0 147 375 1 1
    ATF4 PARS2 0 0 170 185 1 1
    ATF4 NLRP3 0 0 205 205 1 2
    ATF4 OS9 0 0 161 167 1 1
    ATF4 TRIB3 699 900 945 998 1 1
    ATF4 ESRRG 0 0 77 161 1 1
    ATF4 UPF2 0 0 134 193 1 1
    ATF4 COPS8 0 0 0 175 1 1
    ATF4 EGLN1 0 0 248 260 1 1
    ATF4 CASP3 0 0 565 594 1 2
    ATF4 PDIA6 0 0 235 235 1 1
    ATF4 NQO1 0 0 357 357 1 1
    ATF4 PTGS2 0 0 231 230 1 1
    ATF4 EEF1A1 0 0 162 182 1 1
    ATF4 FIGF 0 0 0 214 1 1
    ATF4 MFSD11 0 0 0 190 1 1
    ATF4 EIF4B 0 0 193 193 1 1
    ATF4 NFIB 0 0 72 173 1 1
    ATF4 ZNF354A 0 0 0 160 1 1
    ATF4 GSTM2 0 0 89 153 1 1
    ATF4 EIF2S3 0 900 122 910 1 1
    ATF4 MSH4 0 0 0 207 1 1
    ATF4 RRAGD 0 0 166 393 1 1
    ATF4 GABBR1 270 0 462 633 1 1
    ATF4 SIGMAR1 0 0 218 218 1 1
    ATF4 MAN2A2 0 0 0 258 1 1
    ATF4 DNAJB9 0 0 557 573 1 2
    ATF4 LPIN1 0 0 274 435 1 2
    ATF4 PDIA3 0 0 343 357 1 1
    ATF4 STK17A 0 0 0 167 1 1
    ATF4 DLX5 0 0 208 342 1 1
    ATF4 DAD1 0 0 0 150 1 1
    ATF4 EEF2K 0 0 157 156 1 2
    ATF4 DERL1 0 0 218 231 1 1
    ATF4 FMO5 0 0 0 188 1 1
    ATF4 EIF4EBP2 0 0 142 244 1 1
    ATF4 MAPT 0 0 150 197 1 2
    ATF4 BECN1 0 0 401 414 1 2
    ATF4 CHST13 0 0 0 177 1 1
    ATF4 CAMK2B 0 600 57 633 1 1
    ATF4 CAD 0 0 142 160 1 1
    ATF4 WARS 0 0 233 232 1 1
    ATF4 FGF23 0 0 184 183 1 1
    ATF4 PMAIP1 0 0 391 390 1 1
    ATF4 PIAS1 0 0 307 315 1 1
    ATF4 DNAJC10 0 0 134 152 1 1
    ATF4 TLR2 0 0 166 165 1 1
    ATF4 ZBTB40 0 0 0 202 1 1
    ATF4 HAUS7 472 0 0 472 1 1
    ATF4 TBC1D25 234 0 0 234 1 1
    ATF4 BTRC 870 0 419 921 1 1
    ATF4 MLST8 0 0 182 224 1 2
    ATF4 CAMK4 0 600 81 642 1 1
    ATF4 EIF4A2 0 0 232 299 1 1
    ATF4 UPF1 0 0 211 237 1 1
    ATF4 HSPA5 0 900 805 987 1 2
    ATF4 TFE3 0 0 150 169 1 1
    ATF4 E2F1 0 0 304 304 1 1
    ATF4 SOD2 0 0 261 261 1 1
    ATF4 GPX2 0 0 135 213 1 1
    ATF4 PTH 0 0 321 325 1 1
    ATF4 TKT 0 0 96 158 1 1
    ATF4 KLHDC8A 0 0 93 452 1 1
    ATF4 EPAS1 0 0 94 247 1 2
    ATF4 KRAS 0 0 112 184 1 1
    ATF4 FOXO1 0 0 632 639 1 2
    ATF4 APLP1 0 0 386 399 1 1
    ATF4 FOS 823 0 386 899 1 1
    ATF4 MAN2B1 0 0 0 332 1 1
    ATF4 TWIST1 0 0 161 176 1 1
    ATF4 RRAGC 0 0 181 322 1 1
    ATF4 DEPTOR 0 0 164 216 1 1
    ATF4 COPS6 0 0 60 190 1 1
    ATF4 HM13 0 0 0 157 1 1
    ATF4 ANGPTL4 0 0 108 169 1 1
    ATF4 GTF2F2 270 0 81 300 1 1
    ATF4 RXRA 0 0 61 159 1 1
    ATF4 HMOX2 0 0 433 433 1 1
    ATF4 YPEL4 0 0 279 388 1 1
    ATF4 HAND2 0 0 0 371 1 1
    ATF4 EFNA2 0 0 122 150 1 1
    ATF4 SMG6 0 0 113 174 1 1
    ATF4 SARS 0 0 124 232 1 1
    ATF4 FAM20C 0 0 108 172 1 1
    ATF4 MAP1LC3B 0 0 456 463 1 2
    ATF4 EIF2A 270 0 492 626 1 1
    ATF4 UBC 0 0 92 153 1 1
    ATF4 HSPB1 0 0 150 180 1 1
    ATF4 ATG10 0 0 181 181 1 2
    ATF4 SEC61B 0 0 113 157 1 1
    ATF4 AKT3 0 600 66 618 1 1
    ATF4 MMP13 0 0 193 193 1 1
    ATF4 GPX1 0 0 259 272 1 1
    ATF4 SURF4 0 0 107 414 1 1
    ATF4 FN1 0 0 182 181 1 1
    ATF4 MT-CO1 0 0 81 154 1 1
    ATF4 TBP 270 0 150 352 1 1
    ATF4 CAMK2A 0 600 54 612 1 2
    ATF4 DLX1 0 0 0 413 1 1
    ATF4 STX7 0 0 436 436 1 2
    ATF4 ULK1 0 0 325 325 1 2
    ATF4 TXLNG 0 0 729 729 1 1
    ATF4 NUCB1 0 0 135 198 1 1
    ATF4 SOD3 0 0 125 214 1 1
    ATF4 PRKCA 0 600 103 631 1 1
    ATF4 RPL5 0 0 0 150 1 1
    ATF4 SEL1L 0 0 143 201 1 1
    ATF4 MAPKAPK3 0 800 0 804 1 1
    ATF4 RPS6KA1 0 800 125 825 1 1
    ATF4 MAPK6 0 0 95 151 1 1
    ATF4 ESR1 0 0 205 277 1 1
    ATF4 HMGB1 0 0 125 180 1 2
    ATF4 TXNDC5 0 0 184 201 1 1
    ATF4 PPP1CA 0 600 123 649 1 1
    ATF4 KCNK15 0 0 0 173 1 1
    ATF4 COPS5 0 0 51 151 1 1
    ATF4 CTSK 0 0 195 229 1 1
    ATF4 SMAD7 0 0 135 150 1 1
    ATF4 PDK4 0 0 156 155 1 1
    ATF4 BACE1 0 0 279 279 1 1
    ATF4 ITGAM 0 0 150 156 1 1
    ATF4 OPTN 0 0 123 158 1 2
    ATF4 MAP3K5 0 0 502 513 1 1
    ATF4 MCL1 0 0 298 298 1 2
    ATF4 PLIN2 0 0 104 176 1 1
    ATF4 SIRT1 0 0 321 322 1 2
    ATF4 LMNB1 111 0 112 239 1 1
    ATF4 SPI1 0 0 95 155 1 1
    ATF4 ACOX1 0 0 138 190 1 1
    ATF4 MANF 0 0 337 396 1 1
    ATF4 SLC6A3 0 0 309 309 1 1
    ATF4 PTPN1 0 0 178 199 1 1
    ATF4 XBP1 0 0 831 907 1 2
    ATF4 PDIA5 0 0 143 192 1 1
    ATF4 PRKD1 0 600 61 608 1 1
    ATF4 CAMK1 0 600 0 626 1 1
    ATF4 LGR5 0 0 81 245 1 1
    ATF4 YIPF1 0 0 89 184 1 1
    ATF4 UGGT1 0 0 171 171 1 1
    ATF4 ATG5 0 0 407 419 1 2
    ATF4 NFATC1 0 0 244 243 1 1
    ATF4 ZNF566 0 0 42 206 1 1
    ATF4 COL10A1 0 0 207 207 1 1
    ATF4 MYOD1 0 0 180 179 1 1
    ATF4 DNM1L 0 0 210 210 1 2
    ATF4 YARS 0 0 107 180 1 1
    ATF4 RPL10A 0 0 67 195 1 1
    ATF4 PTEN 0 0 260 276 1 2
    ATF4 TXN2 0 0 106 310 1 1
    ATF4 FMR1NB 0 0 81 222 1 1
    ATF4 GABARAP 0 0 184 201 1 2
    ATF4 NFIA 0 0 108 203 1 1
    ATF4 FEZ1 0 0 84 159 1 1
    ATF4 VEGFA 0 0 370 370 1 1
    ATF4 UCP1 0 0 293 297 1 1
    ATF4 SREBF1 0 0 391 404 1 2
    ATF4 PTH1R 0 0 229 228 1 1
    ATF4 LMNB2 0 0 81 233 1 1
    ATF4 MAPK14 0 0 146 269 1 1
    ATF4 RTCB 0 0 141 178 1 1
    ATF4 STX3 0 0 411 410 1 1
    ATF4 LEP 0 0 293 293 1 1
    ATF4 NFKBIA 192 0 233 353 1 1
    ATF4 NFE2L1 474 0 413 694 1 1
    ATF4 PRKG2 0 600 0 600 1 1
    ATF4 BMP4 0 0 146 167 1 1
    ATF4 TCF4 0 0 233 299 1 1
    ATF4 TTI1 0 0 84 180 1 1
    ATF4 G6PD 0 0 122 177 1 1
    ATF4 ATM 0 0 160 159 1 1
    ATF4 TRIM63 0 0 170 175 1 1
    ATF4 CTSD 0 0 155 154 1 2
    ATF4 DAPK2 270 0 0 366 1 2
    ATF4 DERL3 0 0 277 278 1 1
    ATF4 COL1A1 0 0 334 338 1 1
    ATF4 AMPD1 0 0 84 226 1 1
    ATF4 IL10 0 0 166 165 1 1
    ATF4 GFAP 0 0 141 176 1 2
    ATF4 PA2G4 0 0 118 251 1 1
    ATF4 HIVEP2 0 0 170 324 1 1
    ATF4 ACTG1 0 0 208 244 1 1
    ATF4 NR1H4 0 0 171 247 1 1
    ATF4 GDF15 0 0 204 204 1 1
    ATF4 FOSL2 0 900 203 919 1 1
    ATF4 CNPY2 0 0 127 181 1 1
    ATF4 BTG2 0 0 141 174 1 1
    ATF4 PPP1R15B 0 0 376 392 1 1
    ATF4 FOSB 0 0 181 209 1 1
    ATF4 ATG7 0 0 391 390 1 2
    ATF4 EGLN2 270 0 235 427 1 1
    ATF4 INSIG1 0 0 195 218 1 1
    ATF4 NR1H2 0 0 54 206 1 1
    ATF4 CREBZF 677 0 236 765 1 1
    ATF4 HMGCS1 0 0 155 154 1 1
    ATF4 ENSG00000273637 0 0 0 207 1 1
    ATF4 SATB2 0 0 431 574 1 1
    ATF4 LCN2 0 0 142 165 1 1
    ATF4 TP53 0 0 424 431 1 2
    ATF4 MDM2 314 0 181 414 1 1
    ATF4 TGM2 111 0 47 171 1 1
    ATF4 EGFR 0 0 210 210 1 1
    ATF4 CDK4 0 0 162 180 1 1
    ATF4 PPP1CC 0 600 253 720 1 1
    ATF4 HTT 0 0 206 220 1 1
    ATF4 ZNF354B 0 0 0 160 1 1
    ATF4 MARS 0 0 117 228 1 1
    ATF4 SLC2A1 0 0 170 169 1 1
    ATF4 BOP1 0 0 49 209 1 1
    ATF4 TRAF1 0 0 105 178 1 1
    ATF4 MOB3B 0 0 57 155 1 1
    ATF4 MAP1A 0 0 184 183 1 1
    ATF4 PRKACG 0 800 0 800 1 1
    ATF4 TNFRSF11B 0 0 265 265 1 1
    ATF4 DDIT3 741 800 890 995 1 2
    ATF4 SLC7A5 0 0 330 360 1 1
    ATF4 APAF1 0 0 202 202 1 1
    ATF4 MKNK1 0 800 103 819 1 1
    ATF4 KARS 0 0 61 162 1 1
    ATF4 COL2A1 0 0 210 214 1 1
    ATF4 CHST11 0 0 0 177 1 1
    ATF4 NR4A1 0 0 166 165 1 1
    ATF4 PPARD 0 0 150 267 1 1
    ATF4 FAM175B 270 0 0 345 1 1
    ATF4 CLU 0 0 92 154 1 2
    ATF4 MAFF 0 0 193 210 1 1
    ATF4 IMPACT 0 0 115 170 1 1
    ATF4 FOXE3 0 0 86 168 1 1
    ATF4 NR2F1 0 0 92 179 1 1
    ATF4 GATA3 0 0 70 214 1 1
    ATF4 SERPINH1 0 0 154 153 1 1
    ATF4 PYCR1 0 0 166 201 1 1
    ATF4 GCLM 0 0 604 604 1 1
    ATF4 IMPDH2 0 0 0 168 1 1
    ATF4 ERN1 0 0 805 813 1 2
    ATF4 PRPF31 0 0 0 252 1 1
    ATF4 ABCB9 0 0 0 165 1 1
    ATF4 STAT3 270 0 323 484 1 2
    ATF4 GDNF 0 0 172 171 1 1
    ATF4 VDAC2 0 0 135 228 1 1
    ATF4 C7orf60 0 0 164 163 1 1
    ATF4 DKK2 0 0 95 185 1 1
    ATF4 EIF2AK4 0 0 739 849 1 1
    ATF4 EIF2D 0 0 134 188 1 1
    ATF4 HTR1B 0 0 54 199 1 1
    ATF4 SLC1A6 0 0 0 200 1 1
    ATF4 PARK2 0 0 263 347 1 1
    ATF4 NR0B2 0 0 97 179 1 1
    ATF4 ABCB8 0 0 0 165 1 1
    ATF4 CLOCK 0 0 82 205 1 2
    ATF4 ETHE1 0 0 63 156 1 1
    ATF4 ATP1B1 0 0 46 193 1 1
    ATF4 WFS1 0 0 282 299 1 1
    ATF4 MYC 0 0 362 388 1 2
    ATF4 SLC25A12 0 0 134 245 1 1
    ATF4 KLB 0 0 234 234 1 1
    ATF4 FOXN3 0 0 45 151 1 1
    ATF4 PPRC1 0 0 75 222 1 1
    ATF4 PPARGC1A 0 0 370 370 1 1
    ATF4 PCK1 0 0 147 155 1 1
    ATF4 SDHC 0 0 241 240 1 1
    ATF4 GNAQ 0 0 112 173 1 1
    ATF4 EGLN3 500 0 386 689 1 1
    ATF4 RICTOR 0 0 206 206 1 2
    ATF4 SLC7A1 0 0 219 237 1 1
    ATF4 GLS 0 0 145 164 1 1
    ATF4 TRAF2 0 0 365 404 1 1
    ATF4 IBSP 0 0 412 425 1 1
    ATF4 TMBIM6 0 0 236 236 1 1
    ATF4 GPT2 0 0 246 260 1 1
    ATF4 P4HB 0 0 500 530 1 2
    ATF4 ACP5 0 0 213 213 1 1
    ATF4 ACACA 0 0 162 161 1 1
    ATF4 RIOK1 0 0 46 192 1 1
    ATF4 SLC1A4 0 0 249 255 1 1
    ATF4 ZNF212 192 0 0 204 1 1
    ATF4 CCNT1 0 0 456 456 1 1
    ATF4 EIF5B 0 0 213 213 1 1
    ATF4 SBSN 0 0 53 212 1 1
    ATF4 HDAC5 0 0 140 174 1 1
    ATF4 GPR78 0 0 322 342 1 1
    ATF4 LRP5 0 0 180 179 1 1
    ATF4 MYCN 0 0 134 152 1 1
    ATF4 MKNK2 0 800 60 810 1 1
    ATF4 C9orf72 0 0 113 187 1 2
    ATF4 NGDN 0 0 248 264 1 1
    ATF4 EFNA5 0 0 174 173 1 1
    ATF4 PARK7 0 0 320 319 1 1
    ATF4 NUPR1 0 0 317 317 1 1
    ATF4 ZNF697 0 0 0 202 1 1
    ATF4 AKT2 0 600 95 630 1 1
    ATF4 CIDEA 0 0 144 238 1 1
    ATF4 FKBP11 0 0 228 309 1 1
    ATF4 EIF2B5 0 0 286 306 1 1
    ATF4 NFE2L2 869 0 810 974 1 1
    ATF4 RB1CC1 0 0 206 206 1 2
    ATF4 MAP2K5 0 0 61 228 1 1
    ATF4 MAP2K1 0 0 150 205 1 1
    ATF4 CHAC1 0 900 556 956 1 1
    ATF4 PRCP 0 0 97 153 1 1
    ATF4 CREBBP 805 800 435 976 1 1
    ATF4 GRB10 0 900 157 931 1 1
    ATF4 LONP1 0 0 240 330 1 1
    ATF4 ESRRA 0 0 92 175 1 1
    ATF4 NFE2 271 0 218 405 1 1
    ATF4 PRKACA 0 800 0 800 1 1
    ATF4 NLGN3 192 0 0 192 1 1
    ATF4 USP9X 0 0 162 161 1 1
    ATF4 CREB1 0 800 519 918 1 1
    ATF4 IFNG 0 0 122 165 1 2
    ATF4 BIRC2 0 0 149 164 1 1
    ATF4 IL2RB 0 0 0 302 1 1
    ATF4 SERP1 0 0 220 220 1 1
    ATF4 FOXM1 0 0 141 158 1 1
    ATF4 FBXO32 0 0 195 195 1 2
    ATF4 SLC38A9 0 0 234 234 1 1
    ATF4 HSPD1 0 0 113 155 1 1
    ATF4 TREX2 200 0 0 200 1 1
    ATF4 ANXA5 0 0 414 450 1 1
    ATF4 CCNB1 0 0 160 159 1 1
    ATF4 FGF21 0 0 529 543 1 1
    ATF4 TEF 0 0 45 281 1 1
    ATF4 ATF5 0 650 602 723 1 1
    ATF4 EPO 0 0 171 171 1 1
    ATF4 C12orf66 0 0 118 150 1 1
    ATF4 EIF1B 0 0 0 157 1 1
    ATF4 ZKSCAN3 0 0 145 158 1 2
    ATF4 ITPR2 0 0 183 183 1 1
    ATF4 TAB3 0 0 46 192 1 2
    ATF4 ETAA1 0 0 54 307 1 1
    ATF4 RELA 0 0 150 168 1 1
    ATF4 BCL2L1 0 0 326 325 1 2
    ATF4 DNMT3A 0 0 90 187 1 1
    ATF4 SAPCD2 160 0 0 159 1 1
    ATF4 ATG14 0 0 142 174 1 2
    ATF4 BFSP2 677 0 0 695 1 1
    ATF4 LARS2 0 0 195 212 1 1
    ATF4 GAPDH 0 0 518 552 1 2
    ATF4 GREM1 0 0 90 157 1 1
    ATF4 TENM4 0 0 62 157 1 1
    ATF4 TLR4 0 0 234 234 1 1
    ATF4 SMAD2 0 0 125 190 1 1
    ATF4 SLC20A1 0 0 113 153 1 1
    ATF4 MAP2K7 111 0 181 240 1 1
    ATF4 SMG1 0 0 162 196 1 1
    ATF4 RPS6KA5 0 800 67 809 1 1
    ATF4 GABARAPL2 0 0 170 180 1 2
    ATF4 EDEM3 0 0 108 244 1 1
    ATF4 SP1 0 0 213 293 1 1
    ATF4 NR1H3 0 0 74 223 1 1
    ATF4 IL1B 0 0 337 337 1 1
    ATF4 PRKCB 0 600 76 633 1 2
    ATF4 HIF1A 0 0 423 524 1 2
    ATF4 POLR2C 270 0 90 325 1 1
    ATF4 SLC1A7 0 0 386 402 1 1
    ATF4 PAX2 0 0 244 244 1 1
    ATF4 DARS2 0 0 165 238 1 1
    ATF4 ID1 0 0 157 180 1 1
    ATF4 TARSL2 114 0 181 259 1 1
    ATF4 NDRG1 0 0 161 167 1 1
    ATF4 CXCL8 0 900 243 921 1 1
    ATF4 MFN2 0 0 261 267 1 2
    ATF4 APP 0 0 244 260 1 1
    ATF4 EGR1 0 0 321 331 1 1
    ATF4 SHMT2 0 0 202 300 1 1
    ATF4 ASRGL1 0 0 0 252 1 1
    ATF4 CTNNB1 0 0 298 298 1 1
    ATF4 MAP1LC3A 0 0 235 263 1 2
    ATF4 HRAS 0 0 181 215 1 1
    ATF4 MYF5 0 0 135 153 1 1
    ATF4 PACS2 0 0 202 279 1 1
    ATF4 DNM3 0 0 142 235 1 1
    ATF4 RHO 0 0 182 181 1 1
    ATF4 PSAT1 0 0 369 411 1 1
    ATF4 NOTCH1 0 0 202 202 1 1
    ATF4 MSH5 0 0 0 216 1 1
    ATF4 SEC61A1 0 0 203 218 1 1
    ATF4 CRELD2 0 0 234 259 1 1
    ATF4 FGF13 0 0 154 153 1 1
    ATF4 POTEF 0 0 194 235 1 1
    ATF4 KPNA1 0 0 0 181 1 1
    ATF4 CARS 0 0 229 303 1 1
    ATF4 PTCD3 200 0 0 200 1 1
    ATF4 TAOK3 0 0 96 158 1 1
    ATF4 MTOR 0 0 556 556 1 2
    ATF4 TRIB2 0 0 140 240 1 1
    ATF4 CTRL 0 0 180 179 1 1
    ATF4 SNRPA 0 0 0 228 1 1
    ATF4 NPAS2 0 0 60 197 1 1
    ATF4 IL6 0 0 391 390 1 1
    ATF4 UCP2 0 0 143 161 1 1
    ATF4 ACAN 0 0 136 168 1 1
    ATF4 PLIN1 0 0 95 157 1 1
    ATF4 PIK3C3 0 0 213 213 1 2
    ATF4 PRKG1 0 600 67 610 1 1
    ATF4 RPS6 111 0 246 350 1 1
    ATF4 RPL32 0 0 73 191 1 1
    ATF4 MYOG 0 0 207 207 1 1
    ATF4 LEPRE1 0 0 96 152 1 1
    ATF4 UBE2A 0 0 0 188 1 1
    ATF4 SYVN1 0 0 151 209 1 1
    ATF4 STAT1 0 0 173 173 1 1
    ATF4 LGR4 0 0 87 179 1 1
    ATF4 BATF2 271 0 111 347 1 1
    ATF4 HUNK 0 0 0 203 1 1
    ATF4 KPNA5 0 0 0 171 1 1
    ATF4 SMDT1 0 0 0 268 1 1
    ATF4 SOST 0 0 294 294 1 1
    ATF4 PTPRC 0 0 143 153 1 1
    ATF4 ESR2 0 0 95 185 1 1
    ATF4 SOX9 0 0 260 265 1 1
    ATF4 ENSG00000269590 0 0 0 332 1 1
    ATF4 ELOVL3 0 0 125 153 1 1
    ATF4 ICAM1 0 0 150 174 1 1
    ATF4 CEBPE 497 0 460 787 1 1
    ATF4 GABARAPL1 0 0 174 192 1 2
    ATF4 NOP56 0 0 48 164 1 1
    ATF4 ERP44 0 0 180 219 1 1
    ATF4 SPP1 0 0 301 301 1 1
    ATF4 NKRF 0 0 193 205 1 1
    ATF4 CDKN1A 0 0 276 291 1 2
    ATF4 GATSL3 0 0 217 217 1 1
    ATF4 CHST10 0 0 0 177 1 1
    ATF4 NR1D2 0 0 0 189 1 1
    ATF4 VSX2 0 0 0 187 1 1
    ATF4 HSPA8 0 0 193 232 1 2
    ATF4 GSR 0 0 195 195 1 1
    ATF4 CRTC2 0 800 193 832 1 1
    ATF4 EIF4G1 0 0 268 286 1 2
    ATF4 AR 0 0 127 207 1 1
    ATF4 PARP1 0 0 231 247 1 2
    ATF4 STX1A 0 0 353 353 1 1
    ATF4 STX4 0 0 397 396 1 1
    ATF4 EIF5 0 0 232 265 1 1
    ATF4 BAX 0 0 395 394 1 2
    ATF4 SLC38A2 0 0 401 470 1 1
    ATF4 ATG13 0 0 220 229 1 2
    ATF4 INS 0 0 504 505 1 1
    ATF4 ACTB 0 0 519 543 1 1
    ATF4 FOXG1 0 0 42 152 1 1
    ATF4 EPRS 0 0 123 205 1 1
    ATF4 SLC7A3 0 0 134 184 1 1
    ATF4 EDEM2 0 0 210 232 1 1
    ATF4 GLP1R 0 0 181 186 1 1
    ATF4 DNMT1 0 0 108 172 1 1
    ATF4 CHST9 0 0 0 177 1 1
    ATF4 RPS6KA6 0 800 0 809 1 1
    ATF4 MMP9 0 0 204 204 1 1
    ATF4 B2M 0 0 181 181 1 1
    ATF4 KEAP1 0 0 498 504 1 2
    ATF4 MAPK3 0 600 261 693 1 2
    ATF4 SIRT3 0 0 213 213 1 2
    ATF4 JUNB 111 0 144 243 1 1
    ATF4 PCK2 0 0 213 220 1 1
    ATF4 BNIP3 0 0 264 264 1 2
    ATF4 SQSTM1 0 0 390 403 1 2
    ATF4 FOSL1 489 0 243 612 1 1
    ATF4 TFEB 0 0 325 325 1 2
    ATF4 PDIA2 0 0 143 235 1 1
    ATF4 CREB3L1 0 800 370 868 1 1
    ATF4 TBL2 0 0 212 212 1 1
    ATF4 HSP90AA1 0 0 289 321 1 2
    ATF4 HDAC4 0 0 776 776 1 1
    ATF4 EIF2B1 0 0 161 161 1 1
    ATF4 SP7 0 0 560 583 1 1
    ATF4 HPGDS 0 0 162 161 1 1
    ATF4 CEBPA 458 0 358 807 1 1
    ATF4 HTRA2 0 0 150 203 1 1
    ATF4 PSEN1 0 0 170 169 1 2
    ATF4 ARNTL2 0 0 81 205 1 1
    ATF4 CNTD1 0 0 0 207 1 1
    ATF4 HIATL1 0 0 0 190 1 1
    ATF4 ATF2 271 800 189 875 1 1
    ATF4 ASS1 0 0 107 250 1 1
    ATF4 COX4I1 0 0 194 194 1 1
    ATF4 MTHFD2 0 0 392 467 1 1
    ATF4 NR2F2 0 0 88 176 1 1
    ATF4 LONP2 0 0 71 169 1 1
    ATF4 HNRNPA1 0 0 90 169 1 1
    ATF4 TSC1 0 0 163 163 1 2
    ATF4 PNMA3 0 0 61 160 1 1
    ATF4 KPNA6 0 0 0 181 1 1
    ATF4 BCL2L11 0 0 452 452 1 1
    ATF4 MAFB 271 0 128 337 1 1
    ATF4 DAPK1 0 0 95 297 1 2
    ATF4 MAN2A1 0 0 0 258 1 1
    ATF4 BATF 458 0 90 503 1 1
    ATF4 ITPR3 0 0 368 368 1 1
    ATF4 JUN 734 0 737 936 1 1
    ATF4 EIF2AK1 0 650 635 890 1 1
    ATF4 GORASP2 0 0 68 177 1 1
    ATF4 CASP1 0 0 181 232 1 2
    ATF4 AKT1S1 0 0 171 171 1 1
    ATF4 SNCA 0 0 203 203 1 2
    ATF4 SNAP29 296 0 0 297 1 2
    ATF4 DNTT 0 0 294 294 1 1
    ATF4 MAP2K3 0 0 95 151 1 1
    ATF4 HSPA1A 0 0 180 228 1 1
    ATF4 CALR 0 0 456 485 1 1
    ATF4 BIK 0 0 181 181 1 1
    ATF4 GAP43 0 0 108 174 1 1
    ATF4 CAMK1D 0 600 0 626 1 1
    ATF4 EIF2AK2 0 0 390 606 1 2
    ATF4 SRA1 297 0 0 316 1 1
    ATF4 MFN1 0 0 171 192 1 1
    ATF4 PRKACB 0 800 0 800 1 1
    ATF4 NCOA3 0 0 442 464 1 1
    ATF4 CREB3 271 800 391 920 1 1
    ATF4 SERTAD2 0 0 92 271 1 1
    ATF4 SAT1 0 0 489 489 1 1
    ATF4 TFAM 0 0 284 366 1 1
    ATF4 CHST12 0 0 0 177 1 1
    ATF4 CREB3L2 0 800 325 859 1 1
    ATF4 LAMP2 55 0 138 156 1 2
    ATF4 NME4 0 0 46 152 1 1
    ATF4 CAPN2 0 0 163 218 1 2
    ATF4 TXNL4A 0 0 62 160 1 1
    ATF4 EIF1 0 0 228 381 1 1
    ATF4 ERN2 0 0 469 493 1 1
    ATF4 SOD1 0 0 310 325 1 1
    ATF4 ARNT 0 0 170 202 1 2
    ATF4 RPL3 0 0 0 179 1 1
    ATF4 DNAJC3 0 0 594 614 1 1
    ATF4 HIST2H3PS2 0 0 207 207 1 1
    ATF4 NFIC 0 0 150 181 1 1
    ATF4 HBZ 0 0 845 845 1 1
    ATF4 SESN2 0 0 391 397 1 2
    ATF4 NUP133 0 0 418 418 1 1
    ATF4 GPX4 0 0 235 249 1 1
    ATF4 BATF3 271 0 70 317 1 1
    ATF4 DAPK3 462 0 61 651 1 2
    ATF4 NR3C1 0 0 128 279 1 1
    ATF4 CPT1B 0 0 108 245 1 1
    ATF4 MBTPS2 0 0 464 463 1 1
    ATF4 VPS52 0 0 0 187 1 1
    ATF4 RPS6KB2 0 0 141 159 1 2
    ATF4 COL4A1 0 0 122 162 1 1
    ATF4 HNRNPA2B1 0 0 87 199 1 1
    ATF4 CTGF 0 0 142 161 1 1
    ATF4 PPP1R10 0 0 95 189 1 1
    ATF4 GRINA 0 0 154 153 1 1
    ATF4 GCLC 0 0 357 357 1 1
    ATF4 SKP2 0 0 270 270 1 1
    ATF4 SUMO3 0 0 433 433 1 1
    ATF4 MAPK8 0 0 361 361 1 2
    ATF4 BHLHE40 0 0 170 240 1 1
    ATF4 ADIPOQ 0 0 235 236 1 1
    ATF4 COX6A2 0 0 134 158 1 1
    ATF4 EIF2S2 0 900 325 933 1 1
    ATF4 GABBR2 270 0 48 350 1 1
    ATF4 PCM1 0 0 142 195 1 1
    ATF4 MAPK9 0 0 242 262 1 2
    ATF4 MAN2B2 0 0 0 436 1 1
    ATF4 CYCS 0 0 451 451 1 1
    ATF4 RPS6KA3 0 800 533 907 1 1
    ATF4 GADD45B 0 0 218 256 1 1
    ATF4 SLC1A2 0 0 61 176 1 1
    ATF4 FLCN 0 0 134 220 1 1
    ATF4 ZZZ3 0 0 67 211 1 1
    ATF4 ITPR1 0 0 370 370 1 2
    ATF4 RPS6KA4 0 800 0 804 1 1
    ATF4 CASP9 0 0 404 422 1 1
    ATF4 FASN 68 0 244 265 1 1
    ATF4 ASNSD1 0 0 0 151 1 1
    ATF4 BMP2 0 0 269 288 1 1
    ATF4 EGF 0 0 193 193 1 1
    ATF4 HNF1A 0 0 134 152 1 1
    ATF4 IGFBP1 0 900 81 910 1 1
    ATF4 LPIN3 0 0 67 170 1 1
    ATF4 DICER1 0 0 107 168 1 1
    ATF4 PER3 0 0 92 183 1 1
    ATF4 HSPA4 0 0 336 377 1 1
    ATF4 MIEF1 0 0 0 268 1 1
    ATF4 LPL 0 0 166 165 1 1
    ATF4 TRIB1 0 0 134 279 1 1
    ATF4 PPARA 0 0 335 396 1 1
    ATF4 BPTF 0 0 0 306 1 1
    ATF4 LHX8 0 0 297 311 1 1
    ATF4 ATP6V1D 0 0 45 209 1 1
    ATF4 PDCD4 0 0 150 170 1 1
    ATF4 CYP2E1 0 0 155 154 1 1
    ATF4 RPTOR 0 0 286 286 1 2
    ATF4 CEBPD 275 0 243 646 1 1
    ATF4 HSP90B1 0 0 612 650 1 1
    ATF4 PMF1 0 0 458 457 1 1
    ATF4 CCL2 0 900 261 922 1 2
    ATF4 ALB 0 0 339 397 1 1
    ATF4 CASP8 0 0 324 323 1 2
    ATF4 LEPR 0 0 161 161 1 1
    ATF4 CREB3L3 0 800 395 927 1 1
    ATF4 EIF4A1 0 0 236 323 1 1
    ATF4 RPL19 0 0 161 226 1 1
    ATF4 CASP7 0 0 260 260 1 1
    ATF4 DSPP 0 0 150 193 1 1
    ATF4 HERPUD1 0 900 466 951 1 1
    ATF4 TCF19 0 0 0 183 1 1
    ATF4 MFSD3 0 0 0 190 1 1
    ATF4 EP300 753 800 432 969 1 1
    ATF4 CDK5 0 0 139 160 1 2
    ATF4 ERO1L 0 0 561 594 1 1
    ATF4 CRY2 0 0 103 168 1 1
    ATF4 SPARC 0 0 212 246 1 1
    ATF4 SMAD3 0 0 180 307 1 1
    ATF4 SEC63 0 0 106 154 1 1
    ATF4 HOXA2 0 0 414 414 1 1
    ATF4 ANXA8 0 0 167 167 1 1
    ATF4 CTH 0 0 255 261 1 1
    ATF4 SMG5 0 0 142 195 1 1
    ATF4 TARS 0 0 108 245 1 1
    ATF4 CDK6 0 0 120 150 1 1
    ATF4 HYOU1 270 0 292 472 1 1
    ATF4 HLF 0 0 0 278 1 1
    ATF4 MAPKAPK2 0 800 74 811 1 1
    ATF4 MLXIPL 0 0 209 209 1 1
    ATF4 FNDC5 0 0 246 245 1 1
    ATF4 EIF2B4 0 0 203 203 1 1
    ATF4 TAP2 0 0 0 165 1 1
    ATF4 MAF 458 0 260 581 1 1
    ATF4 NFIL3 0 0 113 342 1 1
    ATF4 SLC3A2 0 0 349 387 1 1
    ATF4 ZBTB1 0 0 67 227 1 1
    ATF4 DPP4 0 0 134 157 1 1
    ATF4 PPP1CB 0 600 0 607 1 1
    ATF4 RPS12 0 0 0 164 1 1
    ATF4 PAX6 0 0 89 153 1 1
    ATF4 ENSG00000257411 0 0 0 186 1 1
    ATF4 FETUB 0 0 57 154 1 1
    ATF4 ATP2A1 0 0 120 175 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0003677 Molecular Function DNA binding enables IDA
    GO:0003677 Molecular Function DNA binding enables ISS
    GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IBA
    GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
    GO:0003700 Molecular Function DNA-binding transcription factor activity enables TAS
    GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IDA
    GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
    GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables ISS
    GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IBA
    GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables IPI
    GO:0008140 Molecular Function cAMP response element binding protein binding enables ISS
    GO:0140296 Molecular Function general transcription initiation factor binding enables IEA
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0043522 Molecular Function leucine zipper domain binding enables IDA
    GO:1990841 Molecular Function promoter-specific chromatin binding enables IDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0046982 Molecular Function protein heterodimerization activity enables ISS
    GO:0019901 Molecular Function protein kinase binding enables IPI
    GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
    GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
    GO:0000976 Molecular Function transcription cis-regulatory region binding contributes_to IDA
    GO:0000976 Molecular Function transcription cis-regulatory region binding enables IDA
    GO:0000976 Molecular Function transcription cis-regulatory region binding enables TAS
    GO:0140468 Biological Process HRI-mediated signaling involved_in IDA
    GO:0070982 Biological Process L-asparagine metabolic process involved_in IDA
    GO:0036499 Biological Process PERK-mediated unfolded protein response involved_in IDA
    GO:0036499 Biological Process PERK-mediated unfolded protein response involved_in ISS
    GO:0036499 Biological Process PERK-mediated unfolded protein response involved_in TAS
    GO:0030282 Biological Process bone mineralization involved_in ISS
    GO:0034644 Biological Process cellular response to UV involved_in ISS
    GO:0034198 Biological Process cellular response to amino acid starvation involved_in ISS
    GO:0042149 Biological Process cellular response to glucose starvation involved_in IMP
    GO:0071456 Biological Process cellular response to hypoxia involved_in IEA
    GO:1990253 Biological Process cellular response to leucine starvation involved_in IDA
    GO:0034599 Biological Process cellular response to oxidative stress involved_in IMP
    GO:0034599 Biological Process cellular response to oxidative stress involved_in ISS
    GO:0032922 Biological Process circadian regulation of gene expression involved_in ISS
    GO:0035162 Biological Process embryonic hemopoiesis involved_in ISS
    GO:0030968 Biological Process endoplasmic reticulum unfolded protein response involved_in ISS
    GO:0007214 Biological Process gamma-aminobutyric acid signaling pathway involved_in IEA
    GO:0006094 Biological Process gluconeogenesis involved_in ISS
    GO:0140467 Biological Process integrated stress response signaling involved_in IDA
    GO:0140467 Biological Process integrated stress response signaling involved_in NAS
    GO:0006874 Biological Process intracellular calcium ion homeostasis involved_in IEA
    GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress involved_in ISS
    GO:0070309 Biological Process lens fiber cell morphogenesis involved_in ISS
    GO:0042789 Biological Process mRNA transcription by RNA polymerase II involved_in ISS
    GO:0120163 Biological Process negative regulation of cold-induced thermogenesis involved_in ISS
    GO:1903377 Biological Process negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway involved_in IGI
    GO:0043267 Biological Process negative regulation of potassium ion transport involved_in IEA
    GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in ISS
    GO:0032057 Biological Process negative regulation of translational initiation in response to stress involved_in ISS
    GO:0030182 Biological Process neuron differentiation involved_in IEA
    GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
    GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IMP
    GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in ISS
    GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in NAS
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in TAS
    GO:0070169 Biological Process positive regulation of biomineral tissue development involved_in IEA
    GO:0010628 Biological Process positive regulation of gene expression involved_in IMP
    GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in ISS
    GO:2000120 Biological Process positive regulation of sodium-dependent phosphate transport involved_in IEA
    GO:0045943 Biological Process positive regulation of transcription by RNA polymerase I involved_in IMP
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISO
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in TAS
    GO:1905461 Biological Process positive regulation of vascular associated smooth muscle cell apoptotic process involved_in IEA
    GO:0010575 Biological Process positive regulation of vascular endothelial growth factor production involved_in IMP
    GO:0006355 Biological Process regulation of DNA-templated transcription involved_in ISS
    GO:0045667 Biological Process regulation of osteoblast differentiation involved_in IDA
    GO:0048167 Biological Process regulation of synaptic plasticity involved_in ISS
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in ISO
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in NAS
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IDA
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IMP
    GO:1990737 Biological Process response to manganese-induced endoplasmic reticulum stress involved_in IEA
    GO:0031667 Biological Process response to nutrient levels involved_in IDA
    GO:0009636 Biological Process response to toxic substance involved_in IEA
    GO:0006366 Biological Process transcription by RNA polymerase II involved_in ISS
    GO:1990590 Cellular Component ATF1-ATF4 transcription factor complex part_of IBA
    GO:1990590 Cellular Component ATF1-ATF4 transcription factor complex part_of IDA
    GO:1990589 Cellular Component ATF4-CREB1 transcription factor complex part_of IBA
    GO:1990589 Cellular Component ATF4-CREB1 transcription factor complex part_of IDA
    GO:1990617 Cellular Component CHOP-ATF4 complex part_of IDA
    GO:1990617 Cellular Component CHOP-ATF4 complex part_of IPI
    GO:1990617 Cellular Component CHOP-ATF4 complex part_of NAS
    GO:1990037 Cellular Component Lewy body core located_in IDA
    GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IPI
    GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of ISO
    GO:0005813 Cellular Component centrosome colocalizes_with IDA
    GO:0000785 Cellular Component chromatin located_in ISA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005737 Cellular Component cytoplasm located_in ISS
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0032590 Cellular Component dendrite membrane located_in IEA
    GO:0043005 Cellular Component neuron projection located_in IDA
    GO:0034399 Cellular Component nuclear periphery located_in IDA
    GO:0016607 Cellular Component nuclear speck located_in IEA
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:0005634 Cellular Component nucleus is_active_in IBA
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0005634 Cellular Component nucleus located_in ISS
    GO:0005634 Cellular Component nucleus located_in NAS
    GO:0032991 Cellular Component protein-containing complex part_of IDA
    Pathways
    Name DB ID
    Cellular responses to stress Reactome R-HSA-2262752
    ATF4 activates genes in response to endoplasmic reticulum stress Reactome R-HSA-380994
    ATF6 (ATF6-alpha) activates chaperones Reactome R-HSA-381033
    PERK regulates gene expression Reactome R-HSA-381042
    Unfolded Protein Response (UPR) Reactome R-HSA-381119
    ATF6 (ATF6-alpha) activates chaperone genes Reactome R-HSA-381183
    Cellular responses to stimuli Reactome R-HSA-8953897
    Response of EIF2AK4 (GCN2) to amino acid deficiency Reactome R-HSA-9633012
    Response of EIF2AK1 (HRI) to heme deficiency Reactome R-HSA-9648895
    Cellular response to starvation Reactome R-HSA-9711097
    Cellular response to chemical stress Reactome R-HSA-9711123
    KEAP1-NFE2L2 pathway Reactome R-HSA-9755511
    Nuclear events mediated by NFE2L2 Reactome R-HSA-9759194
    NFE2L2 regulating anti-oxidant/detoxification enzymes Reactome R-HSA-9818027
    7q11.23 copy number variation syndrome (WP4932) WikiPathways WP4932_r118797
    Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
    Joubert syndrome (WP4656) WikiPathways WP4656_r120396
    Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
    Myometrial relaxation and contraction pathways (WP289) WikiPathways WP289_r122789
    Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
    Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
    mRNA, protein, and metabolite inducation pathway by cyclosporin A (WP3953) WikiPathways WP3953_r106206
    Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
    MAPK signaling pathway (WP382) WikiPathways WP382_r119087
    Circadian rhythm genes (WP3594) WikiPathways WP3594_r117682
    Unfolded protein response (WP4925) WikiPathways WP4925_r123438
    Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
    Renin-angiotensin-aldosterone system (RAAS) (WP4756) WikiPathways WP4756_r120634
    Photodynamic therapy-induced unfolded protein response (WP3613) WikiPathways WP3613_r106539
    PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    LDL- influence on CD14 and TLR4 (WP5272) WikiPathways WP5272_r123542
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001675 4 mRNA transcript variant 1 NC_000022 Reference
    NM_182810 3 mRNA transcript variant 2 NC_000022 Reference