ARSA

arylsulfatase A
General Information
Name arylsulfatase A
Alias
  • arylsulfatase A
  • cerebroside-sulfatase
  • epididymis secretory sperm binding protein
Synonyms ASA MLD
Gene_family Sulfatases
organism Homo sapiens
entrez_id 410
location 22q13.33
transcript_count 9
exon_count 9
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]
      Stringdb Arylsulfatase A; Hydrolyzes cerebroside sulfate; Belongs to the sulfatase family
      nextProt Hydrolyzes cerebroside sulfate.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ARSA BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
    ARSA BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PLD4 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID DEFB135 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID TUBB8 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SUMF1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NCR3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NFXL1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID ERFE GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID ART5 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CTU1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID TMEM25 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NT5C1A GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID ADAMTS12 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CNTNAP3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID UPK1A GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PDIA5 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CNPY3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SCGB1D1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SH2D3A GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PDIA4 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID TNFRSF6B GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CDC45 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID MANF GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SEMA3B GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID HSP90B1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SGSH GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PTPRK GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID DNAJC3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PLAUR GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NDUFV3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID LRPAP1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID HSPD1 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID GAS6 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID GALNS GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID EDN3 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CLGN GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID CALR GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID POGLUT2 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID DNASE2B GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID RAB25 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID FBXL12 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID WNT16 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID TRAV20 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NAAA GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID KLK5 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID MESD GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID ZBTB43 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID FBXO21 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID NXPH4 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SNCA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    ARSA BioGRID HSCB GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID RHOXF2 GeneID BioGRID Two-hybrid
    ARSA BioGRID CCDC22 GeneID BioGRID Two-hybrid
    ARSA BioGRID VENTX GeneID BioGRID Two-hybrid
    ARSA BioGRID TRIP13 GeneID BioGRID Two-hybrid
    ARSA BioGRID PROP1 GeneID BioGRID Two-hybrid
    ARSA BioGRID PKN1 GeneID BioGRID Two-hybrid
    ARSA BioGRID POU1F1 GeneID BioGRID Two-hybrid
    ARSA BioGRID FOXI1 GeneID BioGRID Two-hybrid
    ARSA BioGRID CAMK2B GeneID BioGRID Two-hybrid
    ARSA BioGRID ANXA11 GeneID BioGRID Two-hybrid
    ARSA BioGRID EID2B GeneID BioGRID Two-hybrid
    ARSA BioGRID DPEP2 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID SUSD4 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID INSL5 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID GFPT2 GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PPOX GeneID BioGRID Affinity Capture-MS
    ARSA BioGRID PPIC GeneID BioGRID Two-hybrid
    ARSA BioGRID CETN2 GeneID BioGRID Two-hybrid
    ARSA BioGRID CLEC4G GeneID BioGRID Two-hybrid
    ARSA Protein ARSA GeneID HPRD None
    ARSA Protein GAL3ST1 GeneID HPRD None
    ARSA Protein BMPR2 GeneID HPRD None
    ARSA Protein CTSL GeneID HPRD None
    ARSA BioGRID ARSA GeneID BioGRID Co-crystal Structure; Reconstituted Complex
    StringDB
    A B experiments database textmining combined score hadb nhadb
    ARSA ENSG00000261832 0 0 113 186 1 1
    ARSA SOAT2 0 0 0 250 1 1
    ARSA LMBRD1 0 0 120 212 1 1
    ARSA CYP7B1 0 0 49 242 1 1
    ARSA GALNS 841 0 617 869 1 1
    ARSA NTS 0 0 92 154 1 1
    ARSA NPC1 0 0 318 335 1 2
    ARSA MYH10 0 0 0 221 1 1
    ARSA HYAL4 0 0 0 491 1 1
    ARSA ACP5 0 0 45 226 1 1
    ARSA RAB11FIP5 0 0 0 179 1 1
    ARSA WDPCP 0 0 0 175 1 1
    ARSA GNS 0 0 282 347 1 1
    ARSA ASNA1 0 0 158 157 1 1
    ARSA CAPN3 0 0 431 474 1 1
    ARSA SCARB2 0 0 181 281 1 1
    ARSA FA2H 0 0 217 560 1 1
    ARSA KIF21A 0 0 125 507 1 1
    ARSA CPQ 0 0 167 167 1 1
    ARSA KIF21B 0 0 0 224 1 1
    ARSA FUCA2 0 0 66 165 1 1
    ARSA EIF2B5 0 0 194 209 1 1
    ARSA ATP13A5 0 0 0 187 1 1
    ARSA B3GALT4 0 0 193 357 1 1
    ARSA ARSD 0 500 0 570 1 1
    ARSA PDGFB 0 0 294 294 1 1
    ARSA CYB5A 0 0 306 342 1 1
    ARSA TMEM25 206 0 0 223 1 1
    ARSA B4GALNT1 0 0 166 346 1 1
    ARSA MAP2K1 0 0 43 241 1 1
    ARSA ZPBP 0 0 168 254 1 1
    ARSA JPH3 0 0 46 211 1 1
    ARSA UGT3A1 0 0 195 195 1 1
    ARSA RIMS4 0 0 0 163 1 1
    ARSA TMEM134 0 0 0 175 1 1
    ARSA SHANK1 0 0 61 154 1 1
    ARSA PARK7 0 0 55 158 1 1
    ARSA FPGS 0 0 0 295 1 1
    ARSA CTSA 0 0 241 381 1 1
    ARSA PLP1 0 0 245 244 1 1
    ARSA SUMF1 293 900 561 985 1 1
    ARSA PAEP 0 0 82 162 1 1
    ARSA GAL3ST4 0 0 0 189 1 1
    ARSA B4GALT7 0 0 142 163 1 1
    ARSA MIF4GD 0 0 254 370 1 1
    ARSA RAB2A 0 0 90 231 1 1
    ARSA ZAN 0 0 293 414 1 1
    ARSA GAA 0 0 140 249 1 2
    ARSA PEBP4 0 0 294 325 1 1
    ARSA LAMP1 0 0 137 246 1 2
    ARSA HS3ST2 0 0 0 168 1 1
    ARSA HTT 0 0 107 259 1 1
    ARSA TOR1A 0 0 398 422 1 1
    ARSA FREM2 0 0 0 162 1 1
    ARSA NCDN 0 0 167 310 1 1
    ARSA TXNDC8 0 0 112 231 1 1
    ARSA MCOLN1 0 0 150 314 1 1
    ARSA NASP 0 0 0 163 1 1
    ARSA B3GALT5 0 0 147 210 1 1
    ARSA ARSB 0 800 801 883 1 2
    ARSA CPVL 0 0 0 178 1 1
    ARSA ATP6V0D1 0 0 0 190 1 1
    ARSA POLR3B 0 0 181 203 1 1
    ARSA HSCB 270 0 0 320 1 1
    ARSA TATDN1 0 0 81 225 1 1
    ARSA MESDC2 293 0 0 293 1 1
    ARSA HUWE1 0 0 0 263 1 1
    ARSA TGM1 0 0 0 186 1 1
    ARSA MAML2 0 0 0 217 1 1
    ARSA SERAC1 0 0 67 165 1 1
    ARSA ASPA 0 0 211 305 1 1
    ARSA MTSS1 0 0 82 241 1 1
    ARSA PMM1 0 0 204 232 1 1
    ARSA SETD5 0 0 167 174 1 1
    ARSA CAPN5 0 0 0 504 1 1
    ARSA ZBTB43 431 0 0 431 1 1
    ARSA PDZK1 0 0 88 201 1 1
    ARSA DARS2 0 0 140 186 1 1
    ARSA UGT8 0 900 74 904 1 1
    ARSA CLN3 0 0 135 206 1 2
    ARSA SULF2 0 0 261 354 1 1
    ARSA CTSL 213 0 122 295 1 1
    ARSA CER1 0 0 0 185 1 1
    ARSA SMN1 0 0 141 184 1 1
    ARSA SCPEP1 0 0 61 237 1 1
    ARSA PDS5B 0 0 0 635 1 1
    ARSA ATP6V0E2 0 0 0 189 1 1
    ARSA GLA 0 900 464 945 1 1
    ARSA KCNJ14 0 0 0 367 1 1
    ARSA ARSH 0 500 294 583 1 1
    ARSA CORO7 0 0 180 200 1 1
    ARSA CLCF1 0 0 0 252 1 1
    ARSA PDZD9 0 0 112 265 1 1
    ARSA PSAP 0 0 567 587 1 1
    ARSA AGAP2 0 0 0 228 1 1
    ARSA ACO2 0 0 219 219 1 1
    ARSA PRCP 0 0 0 270 1 1
    ARSA ATP1A3 0 0 61 223 1 1
    ARSA PRSS16 0 0 143 328 1 1
    ARSA NIT1 0 0 0 151 1 1
    ARSA SPSB2 0 0 186 192 1 1
    ARSA BRINP1 0 0 52 199 1 1
    ARSA CORO7-PAM16 0 0 181 181 1 1
    ARSA TRIAP1 0 0 123 257 1 1
    ARSA FCGBP 0 0 203 437 1 1
    ARSA APOA1 0 0 108 158 1 1
    ARSA CAPZA1 0 0 124 324 1 1
    ARSA POMZP3 0 0 0 198 1 1
    ARSA HS3ST1 0 0 0 250 1 1
    ARSA SOX3 0 0 0 260 1 1
    ARSA DPEP2 278 0 0 293 1 1
    ARSA HEPACAM 0 0 134 208 1 1
    ARSA HIRA 0 0 323 337 1 1
    ARSA MGAT2 0 0 571 571 1 1
    ARSA VMO1 0 0 205 224 1 1
    ARSA PMM2 0 0 437 437 1 1
    ARSA SNCA 0 0 184 183 1 2
    ARSA NPC2 0 0 342 363 1 1
    ARSA SGSH 0 0 595 415 1 1
    ARSA ARSI 0 500 210 643 1 1
    ARSA GM2A 0 0 341 387 1 1
    ARSA MANBA 0 0 219 337 1 1
    ARSA HSPA1A 0 0 81 191 1 1
    ARSA FUT3 0 0 115 211 1 1
    ARSA ACRV1 0 0 119 159 1 1
    ARSA ALPPL2 0 0 215 215 1 1
    ARSA TPP1 0 0 401 431 1 1
    ARSA MAML1 0 0 0 188 1 1
    ARSA SERPINA1 0 0 89 180 1 2
    ARSA SI 0 0 307 353 1 1
    ARSA CNGA1 0 0 101 157 1 1
    ARSA MAN2A1 0 0 0 269 1 1
    ARSA MAPK8IP2 0 0 128 179 1 1
    ARSA LRIT1 0 0 270 270 1 1
    ARSA ZBED4 0 0 232 280 1 1
    ARSA AZGP1 0 0 73 283 1 1
    ARSA CTSF 0 0 136 257 1 1
    ARSA ARHGAP11A 0 0 58 154 1 1
    ARSA SUMF2 0 900 400 971 1 1
    ARSA PHF5A 0 0 141 584 1 1
    ARSA RABL2A 0 0 204 221 1 1
    ARSA SULF1 0 0 217 343 1 1
    ARSA KRT1 0 0 0 186 1 1
    ARSA GLB1L3 0 0 0 157 1 1
    ARSA MOB2 0 0 0 172 1 1
    ARSA GAP43 0 0 64 159 1 1
    ARSA TRO 0 0 193 193 1 1
    ARSA PLA2G15 0 0 134 301 1 1
    ARSA ZP3 0 0 161 298 1 1
    ARSA DAND5 0 0 0 150 1 1
    ARSA ZPBP2 0 0 261 482 1 1
    ARSA AGA 0 0 226 225 1 1
    ARSA MTTP 0 0 107 169 1 1
    ARSA TMLHE 0 0 46 154 1 1
    ARSA C7orf43 0 0 112 428 1 1
    ARSA GLB1L2 0 0 0 157 1 1
    ARSA ARSE 0 500 235 576 1 1
    ARSA ENSG00000269590 0 0 0 222 1 1
    ARSA EIF2B1 0 0 236 236 1 1
    ARSA MRPS10 0 0 202 467 1 1
    ARSA HS3ST5 0 0 0 154 1 1
    ARSA TFEB 0 0 123 201 1 2
    ARSA POFUT1 0 0 0 308 1 1
    ARSA TP73 0 0 67 211 1 2
    ARSA UGCG 0 0 284 289 1 1
    ARSA NEU1 0 900 82 906 1 1
    ARSA ACTB 0 0 134 171 1 1
    ARSA SLC11A2 0 0 0 173 1 1
    ARSA DPP7 0 0 117 265 1 1
    ARSA WBP2NL 0 0 231 379 1 1
    ARSA GAL3ST1 213 0 681 745 1 1
    ARSA ACR 0 0 325 431 1 1
    ARSA ARSG 0 800 818 844 1 1
    ARSA NOTCH3 0 0 150 208 1 1
    ARSA DDC 0 0 124 171 1 1
    ARSA DHRS12 0 0 108 199 1 1
    ARSA FBLN1 0 0 67 240 1 1
    ARSA CNTF 0 0 94 221 1 1
    ARSA NEU2 0 900 0 904 1 1
    ARSA TEX101 0 0 107 171 1 1
    ARSA IGLL5 0 0 390 390 1 1
    ARSA ALB 0 0 171 177 1 1
    ARSA OSBPL2 0 0 181 181 1 1
    ARSA CAPN6 0 0 0 347 1 1
    ARSA CD68 0 0 89 174 1 1
    ARSA CTNS 0 0 123 154 1 1
    ARSA SPACA1 0 0 247 363 1 1
    ARSA TBC1D22A 0 0 212 332 1 1
    ARSA TTC5 0 0 74 159 1 1
    ARSA GLB1 0 0 604 651 1 1
    ARSA EIF2B4 0 0 217 217 1 1
    ARSA EIF2B3 0 0 218 226 1 1
    ARSA ATP13A4 0 0 0 187 1 1
    ARSA CERS2 0 0 251 422 1 1
    ARSA FUK 0 0 0 471 1 1
    ARSA PPOX 451 0 49 455 1 1
    ARSA CP 0 0 218 228 1 1
    ARSA PIGM 0 0 156 155 1 1
    ARSA MFGE8 0 0 194 225 1 1
    ARSA FUT9 0 0 0 163 1 1
    ARSA GNPTAB 0 0 241 255 1 1
    ARSA MIPEP 0 0 0 161 1 1
    ARSA ATP6V0D2 0 0 0 190 1 1
    ARSA CAPZA2 0 0 0 165 1 1
    ARSA RSPH3 0 0 161 161 1 1
    ARSA STAB2 0 0 0 200 1 1
    ARSA GJC2 0 0 193 213 1 1
    ARSA EIF5AL1 0 0 321 331 1 1
    ARSA TRIP13 478 0 0 481 1 1
    ARSA PLAUR 280 0 0 280 1 1
    ARSA PTPRK 233 0 0 238 1 1
    ARSA ARSF 0 500 0 547 1 1
    ARSA HSP90B1 0 0 90 186 1 1
    ARSA GNPAT 0 0 91 183 1 1
    ARSA PPARA 0 0 112 152 1 1
    ARSA ACP2 0 0 317 348 1 1
    ARSA GCN1L1 0 0 0 300 1 1
    ARSA CYCS 0 0 90 152 1 1
    ARSA MAN2B2 0 0 69 311 1 1
    ARSA HGSNAT 0 0 57 203 1 1
    ARSA PEX11G 0 0 0 161 1 1
    ARSA RABL2B 0 0 267 283 1 1
    ARSA FUT7 0 0 0 163 1 1
    ARSA RBFOX3 0 0 90 150 1 1
    ARSA PAH 0 0 173 406 1 1
    ARSA ATP13A2 0 0 92 193 1 2
    ARSA GNAI2 0 0 0 279 1 1
    ARSA XDH 0 0 0 182 1 1
    ARSA HSPA2 0 0 465 477 1 1
    ARSA APOB 0 0 113 200 1 1
    ARSA TAF7 0 0 122 361 1 1
    ARSA EID2B 249 0 0 248 1 1
    ARSA TYMP 0 0 120 185 1 1
    ARSA DRAM1 0 0 151 150 1 2
    ARSA LACRT 0 0 151 204 1 1
    ARSA ATN1 0 0 0 226 1 1
    ARSA NAGA 0 0 265 302 1 1
    ARSA PRDX2 0 0 269 285 1 1
    ARSA TFAP2A 192 0 0 192 1 1
    ARSA CYB5R3 0 0 739 741 1 1
    ARSA HEXB 0 0 261 350 1 1
    ARSA HK3 0 0 0 155 1 1
    ARSA LIPA 0 0 244 243 1 1
    ARSA SPAM1 0 0 791 791 1 1
    ARSA STBD1 0 0 161 161 1 2
    ARSA IDUA 0 0 560 606 1 1
    ARSA SPG11 0 0 124 216 1 1
    ARSA GLB1L 0 0 0 157 1 1
    ARSA AOX1 0 0 0 182 1 1
    ARSA SFTPD 0 0 266 266 1 1
    ARSA TMEM230 0 0 0 175 1 1
    ARSA BMPR2 213 0 0 286 1 1
    ARSA HPCA 0 0 740 742 1 1
    ARSA MAP2K2 0 0 0 257 1 1
    ARSA SMN2 0 0 158 201 1 1
    ARSA MUC13 0 0 90 185 1 1
    ARSA GBA 0 0 386 437 1 1
    ARSA CHIT1 0 0 134 152 1 1
    ARSA PPAN-P2RY11 0 0 142 160 1 1
    ARSA IQSEC2 0 0 130 151 1 1
    ARSA TINAGL1 0 0 135 301 1 1
    ARSA HCN1 0 0 174 173 1 1
    ARSA NPL 0 0 170 230 1 1
    ARSA H6PD 0 0 0 170 1 1
    ARSA PRKD2 0 0 0 165 1 1
    ARSA GLTP 0 0 209 258 1 1
    ARSA PRKD3 0 0 0 165 1 1
    ARSA CLN8 0 0 140 214 1 1
    ARSA RNF139 0 0 218 218 1 1
    ARSA NAT16 0 0 226 384 1 1
    ARSA FAM126A 0 0 124 152 1 1
    ARSA NAGLU 0 0 207 269 1 1
    ARSA HEXA 0 0 602 650 1 1
    ARSA NPNT 0 0 106 261 1 1
    ARSA ACRBP 0 0 180 407 1 1
    ARSA ABCD2 0 0 103 215 1 1
    ARSA APOE 0 0 171 190 1 1
    ARSA BBOX1 0 0 0 150 1 1
    ARSA RNASET2 0 0 75 196 1 1
    ARSA CD34 0 0 123 183 1 1
    ARSA KAL1 0 0 0 303 1 1
    ARSA GAL3ST2 0 0 344 445 1 1
    ARSA GFPT2 163 0 0 202 1 1
    ARSA CREM 0 0 139 325 1 1
    ARSA NTN5 0 0 0 302 1 1
    ARSA IGF2R 0 0 282 290 1 1
    ARSA CD1D 0 0 327 327 1 1
    ARSA MGAM 0 0 294 341 1 1
    ARSA FUCA1 0 0 182 192 1 1
    ARSA TSN 0 0 255 457 1 1
    ARSA NEU4 0 900 0 907 1 1
    ARSA GP2 0 0 0 189 1 1
    ARSA MAG 0 0 158 283 1 1
    ARSA CASD1 0 0 0 158 1 1
    ARSA CLEC3B 0 0 102 242 1 1
    ARSA EIF2B2 0 0 220 220 1 1
    ARSA TMEM74 0 0 235 431 1 2
    ARSA ALPP 0 0 194 224 1 1
    ARSA KDSR 0 0 47 172 1 1
    ARSA AARS2 0 0 310 334 1 1
    ARSA GCNT2 0 0 124 175 1 1
    ARSA CES5A 0 0 154 154 1 1
    ARSA AP1S1 0 0 48 193 1 1
    ARSA ATP6V0E1 0 0 0 189 1 1
    ARSA CCDC22 259 0 0 277 1 1
    ARSA GNAO1 0 0 73 233 1 1
    ARSA CEP104 0 0 0 208 1 1
    ARSA MFI2 0 0 193 207 1 1
    ARSA NAAA 0 0 0 245 1 1
    ARSA GNAI3 0 0 123 177 1 2
    ARSA MAN2A2 0 0 0 294 1 1
    ARSA WBP2 0 0 52 253 1 1
    ARSA MAN2B1 0 0 136 325 1 1
    ARSA SPACA4 0 0 73 313 1 1
    ARSA LMO2 0 0 52 198 1 1
    ARSA SLC35B2 0 0 0 153 1 1
    ARSA LGI1 0 0 81 221 1 1
    ARSA GUSB 0 0 630 658 1 1
    ARSA SNRNP35 0 0 0 190 1 1
    ARSA RIMS3 0 0 53 155 1 1
    ARSA AKAP3 0 0 142 328 1 1
    ARSA ELSPBP1 0 0 45 214 1 1
    ARSA CA11 0 0 0 254 1 1
    ARSA NME9 0 0 74 225 1 1
    ARSA FLOT2 0 0 0 213 1 1
    ARSA TG 0 0 161 181 1 1
    ARSA RAB2B 0 0 0 190 1 1
    ARSA IDS 0 0 507 390 1 1
    ARSA SOX1 0 0 63 276 1 1
    ARSA NEU3 0 900 0 907 1 1
    ARSA SMPD1 0 0 416 467 1 1
    ARSA ABCD4 0 0 93 155 1 1
    ARSA APLNR 0 0 0 157 1 1
    ARSA PANK3 0 0 0 152 1 1
    ARSA NXPH3 0 0 216 335 1 1
    ARSA PLA2G6 0 0 160 284 1 1
    ARSA ACSM3 0 0 0 169 1 1
    ARSA GABRG3 0 0 0 183 1 1
    ARSA HSPA1B 0 0 57 152 1 1
    ARSA SLC23A2 0 0 96 183 1 1
    ARSA PDIA6 0 0 153 184 1 1
    ARSA POLR3A 0 0 158 186 1 1
    ARSA STS 0 500 520 603 1 1
    ARSA CD1B 0 0 398 398 1 1
    ARSA ASAH1 0 0 642 675 1 1
    ARSA CREG2 0 0 96 191 1 1
    ARSA SPON2 0 0 0 195 1 1
    ARSA PHF21B 0 0 252 548 1 1
    ARSA SULT1A3 0 0 241 246 1 1
    ARSA ZP2 0 0 162 289 1 1
    ARSA TXNDC2 0 0 74 246 1 1
    ARSA MGEA5 0 0 424 424 1 1
    ARSA PAPSS1 0 0 99 206 1 1
    ARSA ZP4 0 0 0 189 1 1
    ARSA KLHL22 0 0 73 234 1 1
    ARSA PTRF 0 0 0 158 1 1
    ARSA GBA2 0 0 142 415 1 1
    ARSA CLN6 0 0 295 422 1 1
    ARSA PANK2 0 0 74 253 1 1
    ARSA WIPI1 0 0 67 172 1 2
    ARSA CERK 0 0 270 375 1 1
    ARSA PLBD1 0 0 61 155 1 1
    ARSA GLIPR1 0 0 0 312 1 1
    ARSA KRT16 0 0 0 186 1 1
    ARSA FTL 0 0 0 215 1 1
    ARSA MBP 0 0 268 268 1 1
    ARSA DBH 0 0 411 410 1 1
    ARSA B4GALT1 0 0 240 411 1 1
    ARSA FMN1 0 0 398 404 1 1
    ARSA BPNT1 0 0 77 164 1 1
    ARSA PDS5A 0 0 0 315 1 1
    ARSA LCAT 0 0 137 336 1 1
    ARSA B3GALT6 0 0 162 249 1 1
    ARSA G6PD 0 0 0 210 1 1
    ARSA GALNT9 0 0 165 217 1 1
    ARSA ARSJ 0 500 54 641 1 1
    ARSA POLR3H 0 0 0 216 1 1
    ARSA ENG 0 0 45 154 1 1
    ARSA ATP7B 0 0 134 167 1 1
    ARSA CTSD 0 0 392 430 1 2
    ARSA M6PR 0 0 456 456 1 1
    ARSA COL4A3BP 0 0 95 151 1 1
    ARSA MFSD8 0 0 142 274 1 1
    ARSA ANO5 0 0 294 294 1 1
    ARSA NCAM1 0 0 0 303 1 1
    ARSA GNPTG 0 0 201 201 1 1
    ARSA DCAF17 0 0 74 186 1 1
    ARSA GALC 0 900 662 965 1 1
    ARSA PDIA5 130 0 0 162 1 1
    ARSA ARSK 0 500 261 646 1 1
    ARSA ENSG00000241489 0 0 0 456 1 1
    ARSA PANK1 0 0 0 152 1 1
    ARSA PPT1 0 0 160 197 1 1
    ARSA VGLL1 0 0 0 189 1 1
    ARSA GAN 0 0 103 198 1 1
    ARSA PRKD1 0 0 0 165 1 1
    ARSA PAPSS2 0 0 70 171 1 1
    ARSA ATAD1 0 0 167 167 1 1
    ARSA CTSK 0 0 416 429 1 1
    ARSA GALNT5 0 0 142 230 1 1
    ARSA CPNE8 0 0 194 309 1 1
    ARSA ABCD1 0 0 288 428 1 1
    ARSA CTSB 0 0 136 199 1 2
    ARSA MMACHC 0 0 100 179 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0004065 Molecular Function arylsulfatase activity enables IBA
    GO:0005509 Molecular Function calcium ion binding enables IDA
    GO:0004098 Molecular Function cerebroside-sulfatase activity enables IEA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0008484 Molecular Function sulfuric ester hydrolase activity enables IDA
    GO:0006629 Biological Process lipid metabolic process involved_in IEA
    GO:0035578 Cellular Component azurophil granule lumen located_in TAS
    GO:0005788 Cellular Component endoplasmic reticulum lumen located_in TAS
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005576 Cellular Component extracellular region located_in TAS
    GO:0043202 Cellular Component lysosomal lumen located_in TAS
    GO:0005764 Cellular Component lysosome located_in TAS
    Pathways
    Name DB ID
    Metabolism Reactome R-HSA-1430728
    Gamma carboxylation, hypusine formation and arylsulfatase activation Reactome R-HSA-163841
    Glycosphingolipid metabolism Reactome R-HSA-1660662
    The activation of arylsulfatases Reactome R-HSA-1663150
    Innate Immune System Reactome R-HSA-168249
    Immune System Reactome R-HSA-168256
    Metabolism of proteins Reactome R-HSA-392499
    Sphingolipid metabolism Reactome R-HSA-428157
    Metabolism of lipids Reactome R-HSA-556833
    Post-translational protein modification Reactome R-HSA-597592
    Neutrophil degranulation Reactome R-HSA-6798695
    Ether lipid biosynthesis (WP5275) WikiPathways WP5275_r124539
    Degradation pathway of sphingolipids, including diseases (WP4153) WikiPathways WP4153_r123688
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001362782 2 mRNA transcript variant 6 NC_000022 Reference
    XM_047441363 1 mRNA transcript variant X3 NC_000022 Reference
    NM_001085427 3 mRNA transcript variant 4 NC_000022 Reference
    NM_001085428 3 mRNA transcript variant 5 NC_000022 Reference
    XM_024452241 2 mRNA transcript variant X2 NC_000022 Reference
    NM_001085426 3 mRNA transcript variant 3 NC_000022 Reference
    NM_001085425 3 mRNA transcript variant 2 NC_000022 Reference
    XM_011530691 4 mRNA transcript variant X1 NC_000022 Reference
    NM_000487 6 mRNA transcript variant 1 NC_000022 Reference