FAS

Fas cell surface death receptor
General Information
Name Fas cell surface death receptor
Alias
  • tumor necrosis factor receptor superfamily member 6
  • APO-1 cell surface antigen
  • CD95 antigen
  • FASLG receptor
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • TNF receptor superfamily member 6
  • apoptosis antigen 1
  • apoptosis signaling receptor FAS
  • apoptosis-mediating surface antigen FAS
  • mutant tumor necrosis receptor superfamily member 6
  • tumor necrosis factor receptor superfamily, member 6
Synonyms CD95 APO-1 ALPS1A APT1 FAS1 FASTM TNFRSF6
Gene_family Tumor necrosis factor receptor superfamily|Death inducing signaling complex |CD molecules
organism Homo sapiens
entrez_id 355
location 10q23.31
transcript_count 19
exon_count 15
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]
      Stringdb Tumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death- inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS- mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro); CD molecules
      nextProt Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    FAS BioGRID N GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ERBB2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID BSG GeneID BioGRID Proximity Label-MS
    FAS BioGRID CALM1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    FAS BioGRID C9orf72 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TRRAP GeneID BioGRID Affinity Capture-MS
    FAS BioGRID MARCHF8 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID KRT8 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID CCNF GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CDR2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CDC34 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CASP8 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Proximity Label-MS
    FAS BioGRID CAPZA1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID C1QBP GeneID BioGRID Proximity Label-MS
    FAS BioGRID BNIP2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ATP6V1C1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID GET3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID FAS GeneID BioGRID Affinity Capture-Western; PCA; Proximity Label-MS; Two-hybrid
    FAS BioGRID ANXA5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ADD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LPCAT1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TMEM109 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CUEDC2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DDRGK1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID GINS3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CREB3L2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MTMR14 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PALS1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PJA1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CENPK GeneID BioGRID Proximity Label-MS
    FAS BioGRID RINT1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CREBZF GeneID BioGRID Proximity Label-MS
    FAS BioGRID CALCOCO1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ESYT2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CYP20A1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PBXIP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MTFR1L GeneID BioGRID Proximity Label-MS
    FAS BioGRID NSMCE3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ASF1B GeneID BioGRID Proximity Label-MS
    FAS BioGRID OTUB1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID VEZT GeneID BioGRID Proximity Label-MS
    FAS BioGRID LRRC59 GeneID BioGRID Proximity Label-MS
    FAS BioGRID IMPACT GeneID BioGRID Proximity Label-MS
    FAS BioGRID TYW1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID FAIM GeneID BioGRID Proximity Label-MS
    FAS BioGRID ANKZF1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID IFT57 GeneID BioGRID Proximity Label-MS
    FAS BioGRID STX17 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TTC12 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LPCAT2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RETSAT GeneID BioGRID Proximity Label-MS
    FAS BioGRID ANKHD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ERCC6L GeneID BioGRID Proximity Label-MS
    FAS BioGRID KCTD5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TERF2IP GeneID BioGRID Proximity Label-MS
    FAS BioGRID PELO GeneID BioGRID Proximity Label-MS
    FAS BioGRID DNAJB11 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CPSF3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SARAF GeneID BioGRID Proximity Label-MS
    FAS BioGRID OTUD6B GeneID BioGRID Proximity Label-MS
    FAS BioGRID TRMT112 GeneID BioGRID Proximity Label-MS
    FAS BioGRID POMP GeneID BioGRID Proximity Label-MS
    FAS BioGRID HSPA14 GeneID BioGRID Proximity Label-MS
    FAS BioGRID UBXN1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID STRN3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CERS2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SSU72 GeneID BioGRID Proximity Label-MS
    FAS BioGRID COMMD9 GeneID BioGRID Proximity Label-MS
    FAS BioGRID HAUS1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CFAP36 GeneID BioGRID Proximity Label-MS
    FAS BioGRID HAUS8 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SAMD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CCDC97 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LTV1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PPP1R15B GeneID BioGRID Proximity Label-MS
    FAS BioGRID C1orf198 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ACBD6 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DTNBP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID GRWD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CYB5B GeneID BioGRID Proximity Label-MS
    FAS BioGRID UBXN6 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PTGES3L-AARSD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ARPC4-TTLL3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LRRC57 GeneID BioGRID Proximity Label-MS
    FAS BioGRID WASHC2C GeneID BioGRID Proximity Label-MS
    FAS BioGRID STT3B GeneID BioGRID Proximity Label-MS
    FAS BioGRID NSMCE1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID VKORC1L1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ZNG1B GeneID BioGRID Proximity Label-MS
    FAS BioGRID COMMD7 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DHRS13 GeneID BioGRID Proximity Label-MS
    FAS BioGRID UBXN2B GeneID BioGRID Proximity Label-MS
    FAS BioGRID IFFO2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LSM12 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EXOSC6 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DESI1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF3K GeneID BioGRID Proximity Label-MS
    FAS BioGRID R3HCC1L GeneID BioGRID Proximity Label-MS
    FAS BioGRID CACYBP GeneID BioGRID Proximity Label-MS
    FAS BioGRID SND1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KIFBP GeneID BioGRID Proximity Label-MS
    FAS BioGRID C1orf43 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ASF1A GeneID BioGRID Proximity Label-MS
    FAS BioGRID TFIP11 GeneID BioGRID Proximity Label-MS
    FAS BioGRID NUP62 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KPNA6 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MKRN2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ARL2BP GeneID BioGRID Proximity Label-MS
    FAS BioGRID NCS1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID COMMD3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID UFL1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ESYT1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DNAJC16 GeneID BioGRID Proximity Label-MS
    FAS BioGRID BICD2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ATG4B GeneID BioGRID Proximity Label-MS
    FAS BioGRID ERP44 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MAPRE1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID COPG1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ECD GeneID BioGRID Proximity Label-MS
    FAS BioGRID CHP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SEC63 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PWP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CEP43 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RAB35 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SEC61B GeneID BioGRID Proximity Label-MS
    FAS BioGRID TRAFD1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PGRMC1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ENTR1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID HBS1L GeneID BioGRID Proximity Label-MS
    FAS BioGRID PTGES3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MYL12A GeneID BioGRID Proximity Label-MS
    FAS BioGRID RNASEH2A GeneID BioGRID Proximity Label-MS
    FAS BioGRID IPO7 GeneID BioGRID Proximity Label-MS
    FAS BioGRID NPM3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MAEA GeneID BioGRID Proximity Label-MS
    FAS BioGRID POP7 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CCS GeneID BioGRID Proximity Label-MS
    FAS BioGRID ATG13 GeneID BioGRID Proximity Label-MS
    FAS BioGRID NUP93 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PEX5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PEX19 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PSMA5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF2AK2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PRKCD GeneID BioGRID Proximity Label-MS
    FAS BioGRID PPM1G GeneID BioGRID Proximity Label-MS
    FAS BioGRID POLR2E GeneID BioGRID Proximity Label-MS
    FAS BioGRID POLR2C GeneID BioGRID Proximity Label-MS
    FAS BioGRID PDCD2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PCNA GeneID BioGRID Proximity Label-MS
    FAS BioGRID NDUFB10 GeneID BioGRID Proximity Label-MS
    FAS BioGRID NDUFA8 GeneID BioGRID Proximity Label-MS
    FAS BioGRID NAP1L1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MYL6 GeneID BioGRID Proximity Label-MS
    FAS BioGRID MAGEB2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID LBR GeneID BioGRID Proximity Label-MS
    FAS BioGRID IPO5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KPNA3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KPNA2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KPNB1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID KPNA1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID IDI1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID GTF2E1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID ACSL3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EPHX1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF5A GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF4A1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID E2F3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DHFR GeneID BioGRID Proximity Label-MS
    FAS BioGRID CYB5A GeneID BioGRID Proximity Label-MS
    FAS BioGRID CSNK1A1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CLNS1A GeneID BioGRID Proximity Label-MS
    FAS BioGRID CFL1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID CETN2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID BAG2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID COPB2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PNMA1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID PTTG1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID AIP GeneID BioGRID Proximity Label-MS
    FAS BioGRID ZPR1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID DPM1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF3I GeneID BioGRID Proximity Label-MS
    FAS BioGRID EIF3H GeneID BioGRID Proximity Label-MS
    FAS BioGRID STC2 GeneID BioGRID Proximity Label-MS
    FAS BioGRID USP5 GeneID BioGRID Proximity Label-MS
    FAS BioGRID UBXN8 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TRIM26 GeneID BioGRID Proximity Label-MS
    FAS BioGRID YY1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID XBP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID VCP GeneID BioGRID Affinity Capture-MS
    FAS BioGRID UBC GeneID BioGRID Proximity Label-MS
    FAS BioGRID DNAJC7 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TSNAX GeneID BioGRID Proximity Label-MS
    FAS BioGRID TPT1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TP53 GeneID BioGRID Proximity Label-MS
    FAS BioGRID TMF1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SSRP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SRPRA GeneID BioGRID Proximity Label-MS
    FAS BioGRID SOAT1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SNX1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SMARCB1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID SKP1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RPL10 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RNH1 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RBBP4 GeneID BioGRID Proximity Label-MS
    FAS BioGRID RNF123 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
    FAS BioGRID UBAC1 GeneID BioGRID Affinity Capture-Western; PCA; Proximity Label-MS; Reconstituted Complex
    FAS BioGRID RELA GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
    FAS BioGRID SNX27 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID FAM91A1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID C1orf74 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID SFXN5 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CTU2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB2B GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB GeneID BioGRID Affinity Capture-MS
    FAS BioGRID AFG2A GeneID BioGRID Affinity Capture-MS
    FAS BioGRID UGDH GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB2A GeneID BioGRID Affinity Capture-MS
    FAS BioGRID RB1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID PEX1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID MPI GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GPD1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID EP300 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID EFNA2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID DPH1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ARF5 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ALDH3B2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ALDH3B1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ADAM7 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TIMM29 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TMEM25 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB6 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID QTRT1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CAB39L GeneID BioGRID Affinity Capture-MS
    FAS BioGRID RUFY1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID FAM118B GeneID BioGRID Affinity Capture-MS
    FAS BioGRID AFG2B GeneID BioGRID Affinity Capture-MS
    FAS BioGRID DPEP2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID C17orf75 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID AGK GeneID BioGRID Affinity Capture-MS
    FAS BioGRID STYK1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID UFSP2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID MAP1S GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ODR4 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID UGT1A10 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID METTL13 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GCAT GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GPD1L GeneID BioGRID Affinity Capture-MS
    FAS BioGRID RHOBTB3 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GPR182 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID IFT27 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB4B GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB4A GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TUBB3 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ARL4C GeneID BioGRID Affinity Capture-MS
    FAS BioGRID NUBP2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CHD1L GeneID BioGRID Affinity Capture-MS
    FAS BioGRID PICK1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TNFRSF10C GeneID BioGRID Affinity Capture-MS
    FAS BioGRID FADD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid
    FAS BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    FAS BioGRID E5a GeneID BioGRID Affinity Capture-MS
    FAS BioGRID PEA15 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID TRIP6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    FAS BioGRID ATG5 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID EIF2AK3 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID HSPA5 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID PTPN13 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID CUL4B GeneID BioGRID Affinity Capture-MS
    FAS BioGRID DNAJC5 GeneID BioGRID FRET
    FAS BioGRID DAXX GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
    FAS BioGRID PIK3R1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID YES1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID SRC GeneID BioGRID Affinity Capture-Western
    FAS BioGRID ABHD11 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID INTS2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID PDXDC1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CDYL GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GPN3 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID NDUFAF1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID CFLAR GeneID BioGRID Affinity Capture-Western
    FAS BioGRID RAP1A GeneID BioGRID Co-localization; Reconstituted Complex
    FAS BioGRID MAPK8 GeneID BioGRID Co-localization; Co-purification
    FAS BioGRID PRKCA GeneID BioGRID Co-localization
    FAS BioGRID MAP3K5 GeneID BioGRID Affinity Capture-Western; Co-localization
    FAS BioGRID CTNNB1 GeneID BioGRID Co-localization
    FAS BioGRID BID GeneID BioGRID Co-localization; Co-purification
    FAS BioGRID RHOA GeneID BioGRID Co-localization; Co-purification
    FAS BioGRID FASLG GeneID BioGRID Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex
    FAS BioGRID ALDH1L2 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ALDH16A1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID WDR11 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ECSIT GeneID BioGRID Affinity Capture-MS
    FAS BioGRID COX16 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID ACAD9 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID MOCS3 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID MDN1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID EHD1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID GET1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID PRKAG1 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID SUMO1 GeneID BioGRID Reconstituted Complex; Two-hybrid
    FAS BioGRID CAV1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID APOA5 GeneID BioGRID Two-hybrid
    FAS BioGRID TMX1 GeneID BioGRID Two-hybrid
    FAS BioGRID UBQLN1 GeneID BioGRID Two-hybrid
    FAS BioGRID MBD4 GeneID BioGRID Two-hybrid
    FAS BioGRID TP63 GeneID BioGRID Affinity Capture-MS
    FAS BioGRID TCAP GeneID BioGRID Two-hybrid
    FAS BioGRID BAG6 GeneID BioGRID Two-hybrid
    FAS BioGRID HNRNPC GeneID BioGRID Two-hybrid
    FAS BioGRID GADD45A GeneID BioGRID Two-hybrid
    FAS BioGRID CCND3 GeneID BioGRID Two-hybrid
    FAS BioGRID ATP6V0B GeneID BioGRID Two-hybrid
    FAS BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID Ube2i GeneID BioGRID Two-hybrid
    FAS BioGRID PRAM1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID RARA GeneID BioGRID Affinity Capture-Western
    FAS BioGRID PML GeneID BioGRID Affinity Capture-Western
    FAS BioGRID TRADD GeneID BioGRID Affinity Capture-Western
    FAS BioGRID Traf1 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID FAF1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    FAS BioGRID FAF2 GeneID BioGRID Two-hybrid
    FAS BioGRID UBE2I GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    FAS BioGRID TRAF3 GeneID BioGRID Reconstituted Complex
    FAS BioGRID TNF GeneID BioGRID Affinity Capture-Western
    FAS BioGRID BABAM2 GeneID BioGRID Affinity Capture-Western
    FAS Protein LRIF1 GeneID HPRD None
    FAS Protein FEM1B GeneID HPRD None
    FAS Protein FBF1 GeneID HPRD None
    FAS Protein FAIM2 GeneID HPRD None
    FAS Protein UBE2I GeneID HPRD None
    FAS Protein CASP8AP2 GeneID HPRD None
    FAS Protein ERG28 GeneID HPRD None
    FAS Protein TNFSF13 GeneID HPRD None
    FAS Protein FAF1 GeneID HPRD None
    FAS Protein HIPK3 GeneID HPRD None
    FAS Protein TRADD GeneID HPRD None
    FAS Protein RIPK1 GeneID HPRD None
    FAS Protein DAXX GeneID HPRD None
    FAS Protein CRMP1 GeneID HPRD None
    FAS Protein FADD GeneID HPRD None
    FAS Protein APAF1 GeneID HPRD None
    FAS Protein SUMO1 GeneID HPRD None
    FAS Protein CASP8 GeneID HPRD None
    FAS Protein PDCD6 GeneID HPRD None
    FAS Protein CD47 GeneID HPRD None
    FAS Protein ANK3 GeneID HPRD None
    FAS Protein PTPN13 GeneID HPRD None
    FAS Protein BTK GeneID HPRD None
    FAS Protein UBA7 GeneID HPRD None
    FAS Protein RAP1A GeneID HPRD None
    FAS Protein PRKCA GeneID HPRD None
    FAS Protein PTPN6 GeneID HPRD None
    FAS Protein MET GeneID HPRD None
    FAS Protein LCK GeneID HPRD None
    FAS Protein FYN GeneID HPRD None
    FAS Protein FASLG GeneID HPRD None
    FAS Protein FAS GeneID HPRD None
    FAS Protein EGFR GeneID HPRD None
    FAS Protein EEF1A1 GeneID HPRD None
    FAS Protein EZR GeneID HPRD None
    FAS Protein CALM1 GeneID HPRD None
    FAS BioGRID LCK GeneID BioGRID Reconstituted Complex
    FAS BioGRID FYN GeneID BioGRID Affinity Capture-Western
    FAS BioGRID FAIM2 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID CASP8AP2 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID NOL3 GeneID BioGRID Phenotypic Suppression
    FAS BioGRID TNFSF13 GeneID BioGRID Reconstituted Complex
    FAS BioGRID FBF1 GeneID BioGRID Two-hybrid
    FAS BioGRID HIPK3 GeneID BioGRID Affinity Capture-Western
    FAS BioGRID PDCD6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    FAS BioGRID CASP10 GeneID BioGRID Affinity Capture-Western; Co-purification
    FAS BioGRID RIPK1 GeneID BioGRID Two-hybrid
    FAS BioGRID LRIF1 GeneID BioGRID Two-hybrid
    FAS BioGRID ERG28 GeneID BioGRID Two-hybrid
    FAS BioGRID EEF1A1 GeneID BioGRID Two-hybrid
    FAS BioGRID CRMP1 GeneID BioGRID Two-hybrid
    FAS BioGRID EZR GeneID BioGRID Co-purification
    FAS BioGRID TNFRSF1A GeneID BioGRID Co-purification
    FAS BioGRID MSN GeneID BioGRID Co-purification
    FAS BioGRID ARHGDIA GeneID BioGRID Co-purification
    FAS BioGRID TNFRSF10B GeneID BioGRID Co-purification
    FAS Nucleotide TP63 GeneID BIND p63 interacts with CD95.
    FAS None None None BIND An unspecified isoform of Fas interacts with FADD.
    FAS None None None BIND ARC interacts with an unspecified isoform of Fas.
    FAS None None None BIND Fas interacts with FADD.
    FAS Protein SUMO1 GeneID BIND Fas interacts with sentrin.
    FAS Nucleotide RUVBL2 GeneID BIND RUVBL2 (reptin) interacts with the FAS promoter.
    FAS Nucleotide CTNNB1 GeneID BIND CTNNB1 (beta-catenin) interacts with the FAS promoter.
    FAS Nucleotide KAT5 GeneID BIND HTATIP (Tip60) interacts with the FAS promoter.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    FAS TGFB2 0 0 181 181 1 1
    FAS BCL2L1 0 0 687 692 1 2
    FAS ENSG00000026036 0 0 414 414 1 1
    FAS AKT1 0 0 542 548 1 2
    FAS RELA 0 0 316 330 1 1
    FAS PPARG 0 0 220 237 1 1
    FAS TUBB4A 275 0 95 315 1 1
    FAS CCL4L1 0 0 279 299 1 1
    FAS AOC3 0 0 404 404 1 1
    FAS PPP1R13L 0 0 155 174 1 1
    FAS SLC16A12 0 0 0 426 1 1
    FAS NFKB1 0 0 210 270 1 1
    FAS LY96 0 0 96 192 1 1
    FAS CSF2 0 0 469 492 1 1
    FAS CD7 0 0 298 298 1 1
    FAS EFNB3 0 0 45 164 1 1
    FAS CD48 0 0 235 265 1 1
    FAS MKI67 0 0 57 444 1 1
    FAS ZMAT3 0 0 146 158 1 1
    FAS ZAP70 0 0 286 306 1 1
    FAS TLR10 0 0 94 189 1 1
    FAS CLEC7A 0 0 128 162 1 1
    FAS ACKR4 0 0 155 154 1 1
    FAS ITGA4 0 0 519 579 1 1
    FAS CASP6 0 0 501 522 1 1
    FAS STAT4 0 0 136 225 1 1
    FAS SUMO1 500 0 838 916 1 1
    FAS ATF4 0 0 134 152 1 2
    FAS INPP5D 270 0 416 555 1 1
    FAS SLC9A1 0 0 139 161 1 1
    FAS KITLG 0 0 214 214 1 1
    FAS CD4 0 0 770 851 1 1
    FAS MAP3K15 0 0 433 433 1 1
    FAS VCAM1 0 0 298 332 1 1
    FAS IFIT3 0 0 90 153 1 1
    FAS CD247 0 0 299 318 1 1
    FAS ABL1 0 0 236 236 1 1
    FAS MAP2K7 0 900 320 929 1 1
    FAS NOS2 0 0 181 220 1 1
    FAS CD1A 0 0 218 235 1 1
    FAS CX3CL1 0 0 183 200 1 1
    FAS IKBKB 0 900 298 928 1 1
    FAS NLRC4 0 0 146 166 1 2
    FAS CD14 0 0 56 150 1 1
    FAS CD83 0 0 324 347 1 1
    FAS MARCH8 0 0 410 410 1 1
    FAS ATF6 0 0 202 202 1 2
    FAS PANX1 0 0 127 155 1 1
    FAS TNFSF15 0 0 172 187 1 1
    FAS GABARAPL2 0 0 171 171 1 2
    FAS RAP1A 632 0 0 632 1 1
    FAS NMI 0 900 0 904 1 1
    FAS LNP1 0 0 181 199 1 1
    FAS TNFRSF25 0 0 601 282 1 1
    FAS KCNJ6 0 0 326 325 1 1
    FAS TRIAP1 0 0 81 391 1 1
    FAS KIR2DL3 0 0 218 218 1 1
    FAS GAPDH 0 0 418 421 1 2
    FAS GREM1 0 0 0 188 1 1
    FAS SPATA5L1 210 0 0 210 1 1
    FAS PPP2R4 0 0 204 204 1 1
    FAS B3GAT1 0 0 558 558 1 1
    FAS SERPINB6 0 0 0 153 1 1
    FAS PML 270 0 90 378 1 1
    FAS EMR1 0 0 0 261 1 1
    FAS SMAD2 0 0 140 159 1 1
    FAS XIAP 0 0 567 582 1 1
    FAS TLR4 0 0 405 468 1 1
    FAS CD22 0 0 451 519 1 1
    FAS CCL5 0 0 325 381 1 1
    FAS GPT 0 0 267 267 1 1
    FAS DPH1 227 0 0 226 1 1
    FAS PLCG2 0 0 180 191 1 1
    FAS TNFRSF17 0 0 217 262 1 1
    FAS CREB1 0 0 167 173 1 1
    FAS PDE5A 0 0 184 195 1 1
    FAS IL2RB 0 0 460 492 1 1
    FAS IL24 0 0 261 277 1 2
    FAS BCL6 0 0 517 560 1 1
    FAS BIRC2 0 900 508 950 1 1
    FAS IFNG 0 0 492 634 1 2
    FAS PCSK7 0 0 136 195 1 1
    FAS BIRC5 0 0 386 386 1 2
    FAS HLA-DQA2 0 0 306 306 1 1
    FAS CD58 0 0 459 485 1 1
    FAS FEM1C 0 0 398 398 1 1
    FAS FEM1A 0 0 414 414 1 1
    FAS ANK3 213 0 48 218 1 1
    FAS BIRC8 0 0 261 287 1 1
    FAS KRT18 0 0 193 193 1 1
    FAS CYLD 0 0 260 276 1 1
    FAS CXCL10 0 0 363 417 1 1
    FAS TYMS 0 0 193 210 1 1
    FAS MALT1 0 0 209 209 1 1
    FAS TGFBI 0 0 414 435 1 1
    FAS CD1D 0 0 392 415 1 1
    FAS TNFSF8 0 0 274 292 1 1
    FAS PLK1 0 0 339 339 1 1
    FAS AIFM1 0 0 81 291 1 1
    FAS IL6ST 0 0 185 186 1 1
    FAS CXCL13 0 0 310 353 1 1
    FAS MAP3K1 0 0 211 211 1 1
    FAS UGDH 192 0 0 192 1 1
    FAS TNFSF9 0 0 321 325 1 1
    FAS EPO 0 0 181 181 1 1
    FAS TLR9 0 0 381 476 1 1
    FAS GPR183 0 0 134 169 1 1
    FAS GZMK 0 0 181 190 1 1
    FAS IL4R 0 0 229 268 1 1
    FAS ERBB2 0 0 327 327 1 2
    FAS NGF 0 0 342 346 1 1
    FAS UBA7 213 0 0 241 1 1
    FAS LGALS9 0 0 127 196 1 1
    FAS CD34 0 0 414 414 1 1
    FAS PERP 0 0 320 329 1 1
    FAS IRF3 0 0 218 223 1 1
    FAS CR2 0 0 608 641 1 1
    FAS MGMT 0 0 233 249 1 1
    FAS NBL1 0 0 0 186 1 1
    FAS FBF1 192 0 123 278 1 1
    FAS CCNB1 0 0 241 240 1 1
    FAS YES1 486 0 100 517 1 1
    FAS ANXA5 0 0 665 678 1 1
    FAS TNFSF13 270 0 66 317 1 1
    FAS BBC3 0 0 369 369 1 1
    FAS POTEF 0 0 101 155 1 1
    FAS SHISA5 0 0 145 164 1 1
    FAS ITGA6 0 0 184 195 1 1
    FAS CALM1 835 0 44 839 1 1
    FAS C4A 0 0 86 160 1 1
    FAS TNFSF11 0 0 213 229 1 1
    FAS CD47 213 0 323 459 1 1
    FAS CD163 0 0 202 202 1 1
    FAS APOE 0 0 204 209 1 1
    FAS MTOR 0 0 324 333 1 2
    FAS APOBEC3G 0 0 166 177 1 1
    FAS FOXO3 0 0 282 282 1 2
    FAS VDAC3 0 0 99 152 1 1
    FAS ENTPD1 0 0 392 392 1 1
    FAS MMP1 0 0 202 211 1 1
    FAS PTPN13 865 900 695 995 1 1
    FAS ENSG00000270136 0 0 0 186 1 1
    FAS SRC 486 900 485 971 1 1
    FAS NOTCH1 0 0 234 234 1 1
    FAS CD40LG 0 0 634 646 1 1
    FAS IRF8 0 0 155 182 1 1
    FAS PIDD1 0 0 358 382 1 1
    FAS RAG1 0 0 240 300 1 1
    FAS TRAF4 0 0 184 183 1 1
    FAS CDC42 0 0 184 183 1 1
    FAS STAP2 0 0 293 293 1 1
    FAS CXCR4 0 0 503 514 1 2
    FAS HLA-G 0 0 193 203 1 1
    FAS GZMB 0 0 600 605 1 1
    FAS TNFRSF1A 287 800 837 975 1 1
    FAS CDKN3 0 0 234 234 1 1
    FAS TLR3 0 0 333 387 1 1
    FAS BIRC6 0 0 160 178 1 1
    FAS ATG3 0 0 175 175 1 2
    FAS LGALS3 0 0 529 549 1 1
    FAS MIF 0 0 166 178 1 1
    FAS CD52 0 0 218 218 1 1
    FAS BCL2L2-PABPN1 0 0 393 392 1 1
    FAS ENDOG 0 0 401 405 1 1
    FAS STAT1 0 0 391 433 1 1
    FAS CD93 0 0 284 394 1 1
    FAS FLT1 0 0 155 154 1 1
    FAS CD180 0 0 156 163 1 1
    FAS TNFRSF18 0 0 369 381 1 1
    FAS FCRL5 0 0 235 257 1 1
    FAS MOG 0 0 155 192 1 1
    FAS SERPINB7 0 0 0 248 1 1
    FAS HNF4A 0 0 430 430 1 1
    FAS EIF2AK3 270 0 261 437 1 2
    FAS CHD1L 209 0 0 209 1 1
    FAS IL6 0 0 558 619 1 1
    FAS DCXR 0 0 171 171 1 1
    FAS COMT 0 0 0 179 1 1
    FAS STAT6 0 0 180 215 1 1
    FAS BTLA 0 0 261 261 1 1
    FAS PIK3C3 0 0 157 156 1 2
    FAS TNFSF12 0 0 334 334 1 1
    FAS MPO 0 0 181 218 1 1
    FAS IL3RA 0 0 393 509 1 1
    FAS NCR1 0 0 324 323 1 1
    FAS PTPN6 213 0 123 280 1 1
    FAS IL6R 0 0 287 312 1 1
    FAS FOXP3 0 0 630 646 1 1
    FAS HMOX1 0 0 245 259 1 2
    FAS TUBB2A 213 0 0 213 1 1
    FAS TCHP 0 0 324 323 1 1
    FAS NCR2 0 0 276 276 1 1
    FAS NCR3 0 0 283 282 1 1
    FAS CXCL8 0 0 456 470 1 1
    FAS RHOH 0 0 431 432 1 1
    FAS NDUFAF1 193 0 0 193 1 1
    FAS NFATC2 0 0 162 161 1 1
    FAS IL1B 0 0 518 562 1 1
    FAS KLRB1 0 0 380 380 1 1
    FAS ANPEP 0 0 263 289 1 1
    FAS ICOS 0 0 381 410 1 1
    FAS EIF2S1 0 0 290 290 1 2
    FAS TRAF5 0 0 299 327 1 1
    FAS JAK1 0 0 207 235 1 1
    FAS HIF1A 0 0 278 278 1 2
    FAS EDN1 0 0 138 174 1 1
    FAS POSTN 0 0 306 374 1 1
    FAS KDR 0 0 183 183 1 2
    FAS TNFRSF1B 0 0 502 513 1 1
    FAS PACS2 0 0 54 312 1 1
    FAS ENSG00000244255 0 0 57 155 1 1
    FAS B7RP1 0 0 309 360 1 1
    FAS CXCR2 0 0 164 186 1 1
    FAS STAT5B 0 900 324 930 1 1
    FAS PLA2G4A 0 0 80 278 1 1
    FAS TGFB1 0 0 193 308 1 1
    FAS OXSM 0 0 135 189 1 1
    FAS VDAC1 0 0 216 216 1 2
    FAS EGR1 0 0 218 218 1 1
    FAS FCRL4 0 0 286 286 1 1
    FAS APP 0 0 167 167 1 1
    FAS RB1 128 0 108 194 1 2
    FAS PIP4K2B 0 0 292 292 1 1
    FAS FCRL3 0 0 157 177 1 1
    FAS CCR4 0 0 136 174 1 1
    FAS RIPK3 0 900 467 947 1 1
    FAS IFIT1 0 0 127 199 1 1
    FAS FCGR3A 0 0 603 611 1 1
    FAS HRAS 0 0 310 328 1 1
    FAS USP7 0 0 140 158 1 1
    FAS CTNNB1 393 0 323 571 1 1
    FAS TEP1 0 0 0 166 1 1
    FAS RBM5 0 0 218 218 1 1
    FAS CDKN1B 0 0 257 270 1 2
    FAS CD2 0 0 465 465 1 1
    FAS CDK2 0 0 294 309 1 1
    FAS PRKCD 0 0 276 276 1 2
    FAS NR4A1 0 0 217 217 1 1
    FAS CARD18 0 0 295 309 1 1
    FAS CCL19 0 0 232 231 1 1
    FAS SH3BP5 0 0 0 190 1 1
    FAS DFFA 0 0 435 435 1 1
    FAS CTLA4 0 0 739 797 1 1
    FAS CLU 0 0 306 306 1 2
    FAS PACS1 0 0 0 303 1 1
    FAS CALM3 847 0 0 850 1 1
    FAS CD97 0 0 180 231 1 1
    FAS APAF1 213 0 655 786 1 1
    FAS HPRT1 0 0 164 163 1 1
    FAS CD46 0 0 171 176 1 1
    FAS PDCD6 270 0 49 281 1 1
    FAS HLA-DQB1 0 0 52 172 1 1
    FAS RNASEL 0 0 67 203 1 1
    FAS ANXA7 0 0 82 223 1 2
    FAS BAK1 0 0 286 301 1 2
    FAS FEM1B 213 0 509 597 1 1
    FAS CD38 0 0 685 687 1 1
    FAS JAK2 0 0 261 306 1 1
    FAS MYB 0 0 161 175 1 1
    FAS BCL2 0 0 263 263 1 2
    FAS FAF2 192 0 0 204 1 1
    FAS HRK 0 0 333 333 1 1
    FAS STAT3 0 0 452 478 1 2
    FAS HTRA1 0 0 165 165 1 1
    FAS SLC9A3R1 0 0 138 156 1 1
    FAS VDAC2 0 0 112 249 1 1
    FAS CANX 0 0 416 416 1 2
    FAS TXN 0 0 173 183 1 1
    FAS HGF 0 0 218 235 1 1
    FAS CD55 0 0 233 232 1 1
    FAS PTPN22 0 0 96 179 1 1
    FAS GATA3 0 0 242 264 1 1
    FAS CAT 0 0 310 325 1 1
    FAS PECAM1 0 0 391 390 1 1
    FAS MARCH1 0 0 410 410 1 1
    FAS ERN1 0 0 150 434 1 2
    FAS GGCX 0 0 441 527 1 1
    FAS KIR3DL1 0 0 233 232 1 1
    FAS PCSK5 0 0 210 225 1 1
    FAS PSMA3 0 0 0 199 1 1
    FAS MICA 0 0 335 335 1 1
    FAS ITGA5 0 0 181 199 1 1
    FAS SIVA1 0 0 330 330 1 1
    FAS AATF 0 0 90 183 1 1
    FAS PSTPIP1 0 0 415 415 1 1
    FAS RPS6KB1 0 0 202 202 1 2
    FAS BAD 0 0 263 312 1 1
    FAS CDK4 0 0 269 269 1 1
    FAS CFLAR 753 900 849 996 1 1
    FAS EGFR 213 0 935 946 1 1
    FAS TNFRSF4 0 0 455 455 1 1
    FAS REM1 0 0 0 189 1 1
    FAS FCGR1A 0 0 287 288 1 1
    FAS MYD88 0 0 321 404 1 1
    FAS FADD 981 900 989 999 1 2
    FAS CDK1 0 0 253 252 1 1
    FAS MUC1 0 0 203 203 1 1
    FAS HIST2H2BE 0 0 208 208 1 1
    FAS LAMP1 0 0 428 432 1 2
    FAS SERPINE1 0 0 166 185 1 1
    FAS AHR 0 0 170 203 1 1
    FAS CFTR 0 0 236 236 1 1
    FAS NTRK1 0 0 158 164 1 1
    FAS KLRG1 0 0 368 381 1 1
    FAS EPOR 0 0 324 323 1 1
    FAS IFT43 0 0 503 503 1 1
    FAS KLRC1 0 0 392 442 1 1
    FAS MDM2 0 0 401 400 1 1
    FAS TP53 0 900 681 967 1 2
    FAS LCN2 0 0 107 159 1 1
    FAS RRAD 0 0 94 159 1 1
    FAS GNLY 0 0 286 286 1 1
    FAS LOX 0 0 132 174 1 1
    FAS ARF5 238 0 0 254 1 1
    FAS GRAMD4 0 0 146 168 1 1
    FAS LCP2 0 0 145 164 1 1
    FAS NCF1 0 0 173 192 1 1
    FAS NFKBIZ 0 0 107 155 1 1
    FAS TNFRSF11B 0 0 244 265 1 1
    FAS BLNK 0 0 117 150 1 1
    FAS CRADD 0 0 392 392 1 1
    FAS ABCG2 0 0 171 171 1 1
    FAS PDLIM7 0 0 160 159 1 1
    FAS ANXA2 0 0 97 233 1 1
    FAS BCL2L2 0 0 424 424 1 1
    FAS SELPLG 0 0 205 229 1 1
    FAS DDIT3 0 0 267 396 1 2
    FAS ICAM2 0 0 193 247 1 1
    FAS CD19 0 0 681 707 1 1
    FAS UBE2I 486 0 62 603 1 1
    FAS IFIT2 0 0 113 156 1 1
    FAS CSF2RB 0 0 124 185 1 1
    FAS CD274 0 0 468 520 1 1
    FAS TRAF1 0 0 376 411 1 1
    FAS TNFRSF10D 0 0 467 261 1 1
    FAS CCND1 0 0 342 342 1 1
    FAS NOS3 0 0 193 273 1 1
    FAS FLT3LG 0 0 133 165 1 1
    FAS IRAK1 0 0 181 210 1 1
    FAS HLA-E 0 0 232 263 1 1
    FAS CSF3 0 0 294 302 1 1
    FAS HLA-DQB2 0 0 0 208 1 1
    FAS RAF1 0 0 184 183 1 2
    FAS LMNA 0 0 193 193 1 1
    FAS NELFCD 0 0 209 209 1 1
    FAS LY75 0 0 163 182 1 1
    FAS CD70 0 0 393 406 1 1
    FAS IL5 0 0 395 408 1 1
    FAS CD63 0 0 184 183 1 1
    FAS KCNN3 0 0 283 282 1 1
    FAS TNFAIP6 0 0 108 169 1 1
    FAS METTL13 210 0 0 210 1 1
    FAS CCND2 0 0 155 154 1 1
    FAS IFNAR1 0 0 181 251 1 1
    FAS ENSG00000272980 0 0 415 460 1 1
    FAS TFRC 0 0 470 470 1 1
    FAS LAG3 0 0 370 404 1 1
    FAS NFKB2 0 0 195 283 1 1
    FAS GSTP1 0 0 155 154 1 1
    FAS TNFRSF13B 0 0 365 429 1 1
    FAS TNFAIP3 0 0 208 260 1 1
    FAS RUFY1 233 0 0 232 1 1
    FAS SPN 0 0 503 534 1 1
    FAS CASP10 829 900 627 997 1 1
    FAS BCAP31 0 0 150 208 1 1
    FAS TIGIT 0 0 233 253 1 1
    FAS CD9 0 0 206 206 1 1
    FAS S1PR2 0 0 134 191 1 1
    FAS FGF2 0 0 261 277 1 1
    FAS DRAM1 0 0 156 214 1 2
    FAS RELB 0 0 235 270 1 2
    FAS CIDEB 0 0 539 539 1 1
    FAS INTS2 190 0 0 190 1 1
    FAS TNFRSF12A 0 0 218 271 1 1
    FAS BCL2A1 0 0 391 418 1 1
    FAS FASTK 0 0 296 296 1 1
    FAS IFI16 0 0 108 171 1 1
    FAS BMF 0 0 310 325 1 1
    FAS TNFSF14 0 0 141 159 1 1
    FAS TXNIP 0 0 112 173 1 1
    FAS NOL3 209 0 107 280 1 1
    FAS DHX58 0 0 130 173 1 1
    FAS TCF3 0 0 129 151 1 1
    FAS PPIF 0 0 218 218 1 1
    FAS CH25H 0 0 0 207 1 1
    FAS GADD45A 111 0 322 371 1 1
    FAS PEX1 274 0 0 274 1 1
    FAS FUT4 0 0 282 282 1 1
    FAS MAP2K1 0 0 228 235 1 1
    FAS CD80 0 0 629 652 1 1
    FAS C19orf52 233 0 0 232 1 1
    FAS CCL21 0 0 241 257 1 1
    FAS PDGFB 0 0 96 162 1 1
    FAS BRCA1 0 0 180 179 1 1
    FAS CD6 0 0 194 194 1 1
    FAS ITIH4 0 0 390 390 1 1
    FAS IGF1 0 0 283 298 1 1
    FAS ITGA3 0 0 134 152 1 1
    FAS ACAD9 160 0 0 159 1 1
    FAS PPP1R13B 0 900 144 916 1 1
    FAS IRF7 0 0 205 254 1 1
    FAS MAPK1 0 0 260 260 1 2
    FAS CYB5R2 0 0 0 210 1 1
    FAS DDX53 0 0 175 175 1 1
    FAS APOB 0 0 144 181 1 1
    FAS APOL1 0 0 158 158 1 2
    FAS CIDEA 0 0 537 537 1 1
    FAS CSF1R 0 0 234 244 1 1
    FAS WDFY3 0 0 0 248 1 2
    FAS BACH2 0 0 164 163 1 1
    FAS TLR1 0 0 180 239 1 1
    FAS CCND3 111 0 125 188 1 1
    FAS ULBP2 0 0 181 181 1 1
    FAS BTK 213 900 276 943 1 1
    FAS MAP2K5 0 0 67 174 1 1
    FAS SOCS1 0 0 150 218 1 1
    FAS LILRB1 0 0 242 241 1 1
    FAS TNFRSF6B 0 0 414 414 1 1
    FAS TANK 0 0 96 150 1 1
    FAS SOWAHA 0 0 218 246 1 1
    FAS TNF 270 0 708 825 1 1
    FAS HLTF 0 0 81 286 1 1
    FAS HLA-DRB5 0 0 75 151 1 1
    FAS TAB2 0 0 129 152 1 1
    FAS C22orf29 0 0 464 463 1 1
    FAS CD84 0 0 181 187 1 1
    FAS IGF1R 0 0 209 209 1 1
    FAS NT5E 0 0 340 356 1 1
    FAS ITK 0 0 134 157 1 1
    FAS IL7 0 0 503 529 1 1
    FAS IL18 0 0 391 441 1 1
    FAS BDNF 0 0 150 168 1 2
    FAS CD44 0 0 658 699 1 1
    FAS IFNA1 0 0 457 457 1 1
    FAS CASP2 0 0 504 519 1 1
    FAS FAM118B 231 0 0 230 1 1
    FAS HIPK3 270 0 451 625 1 1
    FAS UBE2H 0 0 306 306 1 1
    FAS IL1R1 0 0 309 336 1 1
    FAS IL15 0 0 517 532 1 1
    FAS MMP3 0 0 170 190 1 1
    FAS ITGAE 0 0 393 392 1 1
    FAS MYC 0 0 465 470 1 2
    FAS KLRC3 0 0 0 250 1 1
    FAS IL1RN 0 0 134 171 1 1
    FAS FAIM 0 0 204 218 1 1
    FAS IL2RA 0 0 390 457 1 1
    FAS MMP7 0 0 185 185 1 1
    FAS NAIP 0 0 260 280 1 1
    FAS TOP1 0 0 267 267 1 1
    FAS CDYL 219 0 0 219 1 1
    FAS CEACAM5 0 0 181 181 1 1
    FAS IL27RA 0 0 63 175 1 1
    FAS PIK3CA 0 900 125 908 1 2
    FAS BRE 270 0 48 275 1 1
    FAS CD209 0 0 202 202 1 1
    FAS APOH 0 0 87 202 1 1
    FAS CASP8AP2 270 0 180 500 1 1
    FAS SMPD2 0 0 284 284 1 1
    FAS MEFV 0 0 162 193 1 2
    FAS TMBIM6 0 0 519 519 1 1
    FAS MX1 0 0 171 206 1 1
    FAS TRAF2 0 600 323 723 1 1
    FAS MCL1 0 0 595 603 1 2
    FAS EOMES 0 0 293 293 1 1
    FAS ETS1 0 0 113 164 1 1
    FAS FCGRT 0 0 123 165 1 1
    FAS BFAR 0 0 123 212 1 1
    FAS ENPP7 0 0 152 151 1 1
    FAS ERVW-1 0 0 165 165 1 1
    FAS PCSK1 0 0 252 252 1 1
    FAS INSM2 0 0 325 336 1 1
    FAS CR1 0 0 211 278 1 1
    FAS SIRT1 0 0 210 210 1 2
    FAS ELF4 0 0 95 162 1 1
    FAS AIRE 0 0 113 153 1 1
    FAS EGF 0 0 370 370 1 1
    FAS PRTN3 0 0 180 179 1 1
    FAS CD59 0 0 218 218 1 1
    FAS CTSB 0 0 263 263 1 2
    FAS IL17A 0 0 469 550 1 1
    FAS SPI1 0 0 148 197 1 1
    FAS LMNB1 0 0 203 203 1 1
    FAS MAPK9 0 0 211 211 1 2
    FAS IFNB1 0 0 519 519 1 1
    FAS HMGB1 0 0 246 293 1 2
    FAS CXCL11 0 0 204 204 1 1
    FAS IRF5 0 0 138 286 1 1
    FAS TLR7 0 0 325 517 1 1
    FAS ESR1 0 0 246 245 1 1
    FAS GADD45B 0 0 156 155 1 1
    FAS CHEK2 0 0 258 258 1 1
    FAS CYCS 0 0 700 712 1 1
    FAS NRP1 0 0 288 302 1 1
    FAS LYN 0 0 382 437 1 1
    FAS SEZ6L2 0 0 206 206 1 1
    FAS ANXA13 0 0 53 210 1 1
    FAS ITGAM 0 0 517 542 1 1
    FAS PDCD1 0 0 469 516 1 1
    FAS POU2AF1 0 0 150 173 1 1
    FAS TRAF6 0 0 290 290 1 2
    FAS TUBB 0 0 155 154 1 1
    FAS CASP9 0 0 683 721 1 1
    FAS ACKR2 0 0 263 263 1 1
    FAS MAP3K5 678 900 323 977 1 1
    FAS CXCL9 0 0 281 315 1 1
    FAS ITGB3 0 0 135 175 1 1
    FAS EDAR 0 0 390 390 1 1
    FAS TLR8 0 0 205 274 1 1
    FAS TRIP6 270 0 103 317 1 1
    FAS TIA1 0 0 329 329 1 1
    FAS HSF4 0 0 0 250 1 1
    FAS CCR2 0 0 234 318 1 2
    FAS MAP2K6 0 900 70 903 1 1
    FAS ITGA1 0 0 171 190 1 1
    FAS HSP90B1 0 0 176 177 1 1
    FAS ATG5 486 0 469 715 1 2
    FAS KSR1 0 0 157 156 1 1
    FAS HSPB3 0 0 254 254 1 1
    FAS PDCD4 0 0 134 153 1 1
    FAS CYP2E1 0 0 166 165 1 1
    FAS IRF1 0 0 294 327 1 1
    FAS HLA-C 0 0 134 169 1 1
    FAS RDX 0 0 329 350 1 1
    FAS PLAUR 0 0 155 175 1 1
    FAS DICER1 0 0 163 173 1 1
    FAS CLTC 0 900 0 900 1 1
    FAS PIK3R1 270 900 113 930 1 1
    FAS CX3CR1 0 0 245 250 1 1
    FAS C1QA 0 0 47 185 1 1
    FAS TRIM5 0 0 178 190 1 2
    FAS XBP1 0 0 246 253 1 2
    FAS TP63 270 900 74 928 1 2
    FAS HSPA4 0 0 510 510 1 1
    FAS CXCR3 0 0 518 534 1 1
    FAS PMEL 0 0 181 181 1 1
    FAS HIPK2 0 0 640 663 1 1
    FAS STAT2 0 0 162 180 1 1
    FAS ANXA6 0 0 61 204 1 1
    FAS TERT 0 0 242 241 1 1
    FAS CCR1 0 0 171 220 1 1
    FAS CTU2 240 0 0 239 1 1
    FAS HSPB2 0 0 248 248 1 1
    FAS CD244 0 0 243 242 1 1
    FAS HSPB1 0 900 266 924 1 1
    FAS PTGER4 0 0 120 268 1 1
    FAS GPD1L 203 0 0 203 1 1
    FAS ENSG00000255819 0 0 459 478 1 1
    FAS KCNN4 0 0 63 224 1 1
    FAS FKBP1A 0 0 247 263 1 2
    FAS PRF1 0 0 664 670 1 1
    FAS VAV1 0 0 210 236 1 1
    FAS IL2RG 0 0 230 272 1 1
    FAS NR3C1 0 0 150 171 1 1
    FAS TGFBR1 0 0 101 161 1 1
    FAS MSL2 0 0 457 457 1 1
    FAS P2RX7 0 0 95 151 1 1
    FAS MAP1S 190 0 0 190 1 2
    FAS SPHK1 0 0 155 160 1 2
    FAS HIST2H3PS2 0 0 165 165 1 1
    FAS SNRNP70 0 0 47 195 1 1
    FAS DIABLO 0 0 601 606 1 1
    FAS F2RL3 0 0 0 304 1 1
    FAS ADAM17 0 0 182 181 1 1
    FAS NFKBIB 0 0 150 181 1 1
    FAS HSDL2 0 0 0 254 1 1
    FAS KRIT1 270 0 0 270 1 1
    FAS IFIH1 0 0 183 248 1 1
    FAS SERPINB8 0 0 0 277 1 1
    FAS LRTOMT 0 0 0 179 1 1
    FAS SERPINB9 0 0 295 295 1 1
    FAS MAP1LC3B 270 0 134 352 1 2
    FAS DFFB 0 0 415 414 1 1
    FAS STAB2 0 0 229 228 1 1
    FAS ISG15 0 0 139 177 1 1
    FAS MCAM 0 0 154 166 1 1
    FAS CD1E 0 0 231 261 1 1
    FAS WDFY4 0 0 0 190 1 1
    FAS WDR11 419 0 0 418 1 1
    FAS SERPINB5 0 0 67 269 1 1
    FAS NCAM1 0 0 520 520 1 1
    FAS PHLDA1 0 0 163 166 1 1
    FAS PLK3 0 0 620 620 1 1
    FAS MAP2K4 0 900 194 915 1 1
    FAS TBX21 0 0 452 475 1 1
    FAS ULK1 0 0 142 158 1 2
    FAS GAB4 0 0 82 283 1 1
    FAS PRKCA 600 0 181 658 1 1
    FAS CD79B 0 0 261 277 1 1
    FAS C3 0 0 171 312 1 1
    FAS MAGEA3 0 0 154 153 1 2
    FAS CXCR5 0 0 637 675 1 1
    FAS DEDD2 0 0 189 189 1 1
    FAS MAPK8 677 0 370 787 1 2
    FAS UNC5B 0 0 303 303 1 1
    FAS ARG1 0 0 181 198 1 1
    FAS BMP1 0 0 471 471 1 1
    FAS ENSG00000255641 0 0 0 250 1 1
    FAS PTK2 0 0 203 203 1 1
    FAS RAG2 0 0 161 183 1 1
    FAS IKBKG 0 900 294 926 1 1
    FAS CCR7 0 0 681 829 1 1
    FAS CCR9 0 0 209 213 1 1
    FAS MARCH4 0 0 134 166 1 1
    FAS RARA 270 0 70 292 1 1
    FAS IGHV4-38-2 0 0 391 390 1 1
    FAS C1QC 0 0 60 196 1 1
    FAS KLRC2 0 0 170 227 1 1
    FAS KLRD1 0 0 335 335 1 1
    FAS FN1 0 0 325 339 1 1
    FAS ITGA2B 0 0 128 171 1 1
    FAS BCL2L10 0 0 398 398 1 1
    FAS CDH1 0 0 268 268 1 1
    FAS THBD 0 0 135 170 1 1
    FAS PRKCZ 0 0 194 194 1 1
    FAS CD33 0 0 283 282 1 1
    FAS ATM 0 0 325 325 1 1
    FAS PTPRJ 0 0 127 163 1 1
    FAS EZR 458 900 328 961 1 1
    FAS KCNA3 0 0 134 201 1 1
    FAS MFGE8 0 0 122 154 1 1
    FAS TRIM21 0 0 96 194 1 1
    FAS CTSD 0 0 279 279 1 2
    FAS PLG 0 0 164 163 1 1
    FAS ALCAM 0 0 217 217 1 1
    FAS TNFRSF10C 0 0 503 554 1 1
    FAS DDX58 0 0 218 258 1 1
    FAS AIM2 0 0 160 174 1 1
    FAS CCL22 0 0 159 177 1 1
    FAS FCGR3B 0 0 603 611 1 1
    FAS CDK6 0 0 225 241 1 1
    FAS C4B 0 0 92 165 1 1
    FAS ENG 0 0 193 210 1 1
    FAS CCL3 0 0 325 373 1 1
    FAS CERS2 0 0 174 192 1 1
    FAS ICAM3 0 0 193 202 1 1
    FAS CCR10 0 0 170 169 1 1
    FAS HLA-A 0 0 247 278 1 1
    FAS ACTG1 0 0 122 164 1 1
    FAS FAIM2 270 900 502 960 1 1
    FAS TRAIP 0 0 357 357 1 1
    FAS DYRK1B 0 0 309 334 1 1
    FAS TRADD 462 900 685 983 1 1
    FAS ATG7 0 0 183 183 1 2
    FAS IL1A 0 0 322 350 1 1
    FAS GBP1 0 0 61 187 1 1
    FAS CCL4 0 0 325 360 1 1
    FAS CRYGC 0 0 203 203 1 1
    FAS SELE 0 0 217 247 1 1
    FAS MAVS 0 0 136 158 1 1
    FAS TGFBR2 0 0 125 151 1 1
    FAS ITGB4 0 0 108 163 1 1
    FAS RNF31 0 0 154 179 1 1
    FAS IRAK4 0 0 113 172 1 1
    FAS FLT3 0 0 209 209 1 1
    FAS MAF 0 0 171 183 1 1
    FAS CCL20 0 0 215 233 1 1
    FAS SNAI1 0 0 149 197 1 1
    FAS IL10 0 0 562 606 1 1
    FAS CXCR6 0 0 181 198 1 1
    FAS BSG 0 0 174 173 1 1
    FAS CLIP3 0 0 193 193 1 1
    FAS DPP4 0 0 286 309 1 1
    FAS CASP7 0 900 509 953 1 1
    FAS MME 0 0 377 377 1 1
    FAS ID3 0 0 163 163 1 1
    FAS MBP 0 0 204 220 1 1
    FAS PTEN 0 0 370 370 1 2
    FAS ITGB1 0 0 301 316 1 1
    FAS BST2 0 0 150 191 1 1
    FAS TNFAIP8L2 0 0 398 398 1 1
    FAS VEGFA 0 0 421 421 1 1
    FAS IRF4 0 0 329 365 1 1
    FAS ANXA3 0 0 62 205 1 1
    FAS RC3H1 0 0 95 230 1 1
    FAS CCL2 0 0 391 402 1 2
    FAS NFATC1 0 0 113 158 1 1
    FAS CD200 0 0 203 203 1 1
    FAS PDCD1LG2 0 0 381 432 1 1
    FAS CASP8 914 900 987 999 1 2
    FAS CD68 0 0 310 327 1 1
    FAS ALB 0 0 451 521 1 1
    FAS IL16 0 0 150 168 1 1
    FAS ENPEP 0 0 181 202 1 1
    FAS IDO1 0 0 206 206 1 1
    FAS IGLL5 0 0 162 161 1 1
    FAS FCER1G 0 0 74 158 1 1
    FAS CERK 0 0 127 157 1 1
    FAS CASP5 0 0 194 240 1 1
    FAS CD276 0 0 457 479 1 1
    FAS NFKBIA 0 0 415 428 1 1
    FAS KIT 0 0 325 325 1 1
    FAS NEU2 0 0 193 193 1 1
    FAS TUBB3 252 0 90 290 1 1
    FAS TNFRSF10A 0 600 844 739 1 1
    FAS COMMD3-BMI1 0 0 156 155 1 1
    FAS SYK 0 900 268 928 1 1
    FAS MLLT4 0 0 277 287 1 1
    FAS LEP 0 0 170 193 1 1
    FAS SERPINB1 0 0 0 179 1 1
    FAS S1PR1 0 0 162 184 1 1
    FAS AMBP 0 0 167 185 1 1
    FAS TP53AIP1 0 0 208 208 1 1
    FAS SMAD3 0 0 141 165 1 1
    FAS BIRC3 0 900 421 946 1 1
    FAS ANXA8 0 0 438 438 1 1
    FAS IL17F 0 0 150 211 1 1
    FAS IL4 0 0 560 590 1 1
    FAS SREBF1 0 0 161 161 1 2
    FAS FCGR2A 0 0 391 417 1 1
    FAS MAPK10 0 0 291 290 1 2
    FAS NGFR 0 0 470 470 1 1
    FAS IL9 0 0 233 248 1 1
    FAS CD79A 0 0 247 316 1 1
    FAS TP53BP2 0 900 145 923 1 1
    FAS BAG1 0 0 255 254 1 2
    FAS MAPK14 0 0 219 290 1 1
    FAS PDGFRB 0 0 125 157 1 1
    FAS CD226 0 0 398 398 1 1
    FAS LMNB2 0 0 157 156 1 1
    FAS IL21R 0 0 280 307 1 1
    FAS TROVE2 0 0 53 156 1 1
    FAS DOCK8 0 0 143 214 1 1
    FAS TNFRSF9 0 0 459 462 1 1
    FAS RORC 0 0 139 215 1 1
    FAS EP300 0 0 150 160 1 1
    FAS MAPK3 0 0 358 358 1 2
    FAS PAX5 0 0 414 415 1 1
    FAS MMP9 0 0 321 322 1 1
    FAS B2M 0 0 262 341 1 1
    FAS THY1 0 0 324 441 1 1
    FAS PROM1 0 0 234 234 1 1
    FAS CD28 0 0 739 856 1 1
    FAS CD5 0 0 519 579 1 1
    FAS ANXA4 0 0 81 222 1 1
    FAS CYBB 0 0 164 187 1 1
    FAS TRIM22 0 0 57 206 1 1
    FAS FCGR2B 0 0 560 578 1 1
    FAS SQSTM1 270 0 113 330 1 2
    FAS BNIP3 0 0 207 248 1 2
    FAS MICB 0 0 229 228 1 1
    FAS ACTB 0 0 459 491 1 1
    FAS ASAH1 0 0 218 218 1 1
    FAS ATG13 0 0 184 183 1 2
    FAS INS 0 0 334 334 1 1
    FAS CD1B 0 0 258 284 1 1
    FAS SELP 0 0 241 257 1 1
    FAS UFSP2 219 0 0 219 1 1
    FAS IL13 0 0 372 383 1 1
    FAS TNFRSF10B 287 600 752 802 1 1
    FAS ATG12 0 0 180 197 1 2
    FAS MSN 287 0 181 415 1 1
    FAS COMTD1 0 0 0 553 1 1
    FAS PRKCQ 0 0 122 165 1 2
    FAS NDUFB11 0 0 166 165 1 1
    FAS C17orf75 644 0 0 644 1 1
    FAS RFK 0 0 260 260 1 1
    FAS TNFSF13B 0 0 456 543 1 1
    FAS SELL 0 0 665 678 1 1
    FAS CD8B 0 0 156 214 1 1
    FAS NOTCH2 0 0 113 155 1 1
    FAS ACE 0 0 125 157 1 1
    FAS DNMT1 0 0 123 155 1 1
    FAS CD40 0 0 836 848 1 1
    FAS ARHGDIA 287 0 97 328 1 1
    FAS ITGB7 0 0 201 201 1 1
    FAS F3 0 0 150 181 1 1
    FAS CASP3 0 360 739 845 1 2
    FAS ERBB3 0 0 142 152 1 1
    FAS RPSA 0 0 107 190 1 1
    FAS IFIT5 0 0 0 174 1 1
    FAS AICDA 0 0 390 445 1 1
    FAS TUBB2B 213 0 0 213 1 1
    FAS HTRA2 0 0 367 367 1 1
    FAS LAIR1 0 0 167 167 1 1
    FAS PTGS2 0 0 283 314 1 1
    FAS CCL11 0 0 181 193 1 1
    FAS PSMB9 0 0 161 199 1 1
    FAS TP73 0 900 95 909 1 2
    FAS TNFRSF21 0 0 517 524 1 1
    FAS SLAMF6 0 0 123 209 1 1
    FAS AFP 0 0 134 188 1 1
    FAS UGCG 0 0 180 179 1 1
    FAS DAXX 870 900 615 995 1 1
    FAS CRP 0 0 270 288 1 1
    FAS IL3 0 0 323 332 1 1
    FAS LTB 0 0 95 188 1 1
    FAS CARD16 0 0 305 374 1 1
    FAS HSP90AA1 0 0 294 304 1 2
    FAS NLRP3 0 0 272 295 1 2
    FAS REL 0 0 271 286 1 1
    FAS KIR2DL1 0 0 249 248 1 1
    FAS HPGDS 0 0 244 243 1 1
    FAS IL21 0 0 218 301 1 1
    FAS IL33 0 0 125 164 1 1
    FAS APCS 0 0 113 151 1 1
    FAS CXCL1 0 0 212 257 1 1
    FAS SIRT7 0 0 306 306 1 1
    FAS CSF1 0 0 209 286 1 1
    FAS IL22 0 0 219 219 1 1
    FAS MS4A1 0 0 103 296 1 1
    FAS ULBP1 0 0 201 201 1 1
    FAS RIPK1 476 900 734 985 1 1
    FAS PRDM1 0 0 369 434 1 1
    FAS HDAC1 0 0 158 165 1 2
    FAS ZEB1 0 0 171 171 1 1
    FAS CD24 0 0 451 451 1 1
    FAS ICAM1 0 0 557 580 1 1
    FAS UNC93B1 0 0 57 184 1 1
    FAS SLC25A38 0 0 0 169 1 1
    FAS PTGER2 0 0 57 288 1 1
    FAS LTBR 0 0 294 192 1 1
    FAS GABARAPL1 0 0 162 161 1 2
    FAS STK4 0 0 113 174 1 1
    FAS ITGAV 0 0 150 151 1 1
    FAS GPR126 0 0 294 294 1 1
    FAS SMDT1 0 0 170 169 1 1
    FAS SMPD1 0 900 504 948 1 1
    FAS BCL10 0 0 260 260 1 1
    FAS CEBPB 0 0 129 161 1 1
    FAS MLKL 0 0 394 419 1 1
    FAS PTPRC 0 0 666 693 1 1
    FAS CD160 0 0 193 193 1 1
    FAS NOD2 0 0 147 171 1 1
    FAS XKR8 0 0 112 156 1 1
    FAS CIITA 0 0 155 155 1 1
    FAS CXCR1 0 0 170 182 1 1
    FAS ESR2 0 0 124 155 1 1
    FAS TG 0 0 97 150 1 1
    FAS TLR5 0 0 178 194 1 1
    FAS SH2D1A 0 0 177 191 1 1
    FAS CHUK 0 900 293 927 1 1
    FAS KLRK1 0 0 459 478 1 1
    FAS KLF2 0 0 295 295 1 1
    FAS TIMP1 0 0 236 236 1 1
    FAS GPR29 0 0 415 460 1 1
    FAS BAX 0 0 452 452 1 2
    FAS CXCL12 0 0 314 329 1 1
    FAS ITGAX 0 0 556 577 1 1
    FAS CDKN1A 0 0 465 498 1 2
    FAS SPP1 0 0 166 180 1 1
    FAS MRC1 0 0 156 174 1 1
    FAS GSK3B 0 0 113 176 1 2
    FAS CSF2RA 0 0 134 217 1 1
    FAS TNFRSF14 0 0 260 152 1 1
    FAS CD1C 0 0 277 305 1 1
    FAS HSPA8 0 0 108 471 1 2
    FAS BID 676 900 499 982 1 1
    FAS CASP4 0 0 305 369 1 2
    FAS PARP1 0 0 293 301 1 2
    FAS RHOA 676 0 170 719 1 1
    FAS CDKN2A 0 0 298 313 1 2
    FAS AR 0 0 150 169 1 1
    FAS CXCL16 0 0 175 175 1 1
    FAS EPCAM 0 0 212 212 1 1
    FAS CALM2 800 0 0 803 1 1
    FAS IFNGR1 0 0 147 241 1 1
    FAS HLA-B 0 0 122 164 1 1
    FAS CCL17 0 0 150 185 1 1
    FAS TNFRSF13C 0 0 391 404 1 1
    FAS CD3E 0 0 243 373 1 1
    FAS SLAMF1 0 0 321 353 1 1
    FAS SOD2 0 0 158 157 1 1
    FAS MMP2 0 0 276 276 1 1
    FAS TCF7 0 0 150 172 1 1
    FAS RIPK2 0 900 208 919 1 1
    FAS PDXDC1 219 0 0 219 1 1
    FAS FOXO1 0 0 213 213 1 2
    FAS KRAS 0 0 260 310 1 1
    FAS RPS14 0 0 45 224 1 1
    FAS TNFSF4 0 0 296 327 1 1
    FAS ITGB2 0 0 184 211 1 1
    FAS TNFRSF8 0 0 516 516 1 1
    FAS TAGLN3 0 0 195 195 1 1
    FAS CALR 0 0 266 266 1 1
    FAS BIK 0 0 276 276 1 1
    FAS CD8A 0 0 760 789 1 1
    FAS UCHL1 0 0 324 339 1 1
    FAS NRAS 0 0 141 165 1 1
    FAS HAVCR2 0 0 406 409 1 1
    FAS CASP14 0 0 95 201 1 1
    FAS SNRPB 0 0 0 189 1 1
    FAS IGFBP3 0 0 155 169 1 1
    FAS HSPA5 270 0 285 455 1 2
    FAS CD96 0 0 120 175 1 1
    FAS NOP2 0 0 328 328 1 1
    FAS FAF1 775 900 683 992 1 1
    FAS AASDH 0 0 54 547 1 1
    FAS ERN2 0 0 0 256 1 1
    FAS LTA 0 0 293 426 1 1
    FAS SOD1 0 0 123 160 1 1
    FAS STAT5A 0 900 325 932 1 1
    FAS CDC25C 0 0 186 186 1 1
    FAS CD69 0 0 681 722 1 1
    FAS BIRC7 0 0 286 301 1 1
    FAS CCR5 0 0 556 677 1 1
    FAS BMI1 0 0 161 161 1 1
    FAS IL7R 0 0 594 607 1 1
    FAS IL15RA 0 0 124 175 1 1
    FAS SOCS3 0 0 134 177 1 1
    FAS LAMP2 0 0 142 201 1 2
    FAS CCRL2 0 0 403 417 1 1
    FAS IL17RA 0 0 113 156 1 1
    FAS LCK 486 0 335 657 1 1
    FAS FYN 669 0 265 748 1 1
    FAS NFKBIE 0 0 108 168 1 1
    FAS FASLG 870 900 989 999 1 1
    FAS GRB2 0 0 161 183 1 1
    FAS PVRL2 0 0 233 239 1 1
    FAS FOS 0 0 273 273 1 1
    FAS CARD11 0 0 211 211 1 1
    FAS NOD1 0 0 155 173 1 1
    FAS PDIA3 0 0 134 161 1 1
    FAS DAPK1 0 0 210 210 1 2
    FAS TYK2 0 0 123 161 1 1
    FAS CD81 0 0 241 240 1 1
    FAS RHOBTB3 219 0 0 219 1 1
    FAS SFXN5 219 0 0 219 1 1
    FAS NAALADL1 0 0 420 420 1 1
    FAS PLCG1 270 0 843 880 1 1
    FAS JUN 0 0 504 504 1 1
    FAS BATF 0 0 193 212 1 1
    FAS CD72 0 0 181 204 1 1
    FAS ENSG00000277117 0 0 310 361 1 1
    FAS SERPINA1 0 0 157 156 1 2
    FAS CYP19A1 0 0 103 155 1 1
    FAS ENSG00000173366 0 0 374 470 1 1
    FAS SIGLEC1 0 0 201 226 1 1
    FAS IL18R1 0 0 108 172 1 1
    FAS IL10RA 0 0 150 191 1 1
    FAS GZMA 0 0 392 405 1 1
    FAS CD86 0 0 635 656 1 1
    FAS ITGAL 0 0 509 519 1 1
    FAS BCL2L11 0 0 556 566 1 1
    FAS SERPINB2 0 0 54 259 1 1
    FAS JAK3 0 0 216 233 1 1
    FAS MAP2K3 0 900 136 909 1 1
    FAS ABHD11 419 0 0 418 1 1
    FAS BOK 0 0 194 194 1 2
    FAS TRAF3 270 0 278 450 1 2
    FAS MET 213 0 194 353 1 1
    FAS PEA15 270 0 222 420 1 1
    FAS RAET1G 0 0 306 306 1 1
    FAS CERS5 0 0 193 210 1 1
    FAS HSPA1A 0 0 112 208 1 1
    FAS DUSP1 0 0 170 169 1 1
    FAS CERS6 0 0 445 470 1 1
    FAS TLR2 0 0 321 373 1 1
    FAS PIK3CB 0 900 74 903 1 1
    FAS CAV1 486 0 700 842 1 1
    FAS TNFSF10 0 600 710 883 1 2
    FAS HLA-DRB1 0 0 95 170 1 1
    FAS PMAIP1 0 0 560 560 1 1
    FAS ANXA1 0 0 147 190 1 1
    FAS ITGA2 0 0 210 247 1 1
    FAS PRAM1 270 0 43 271 1 1
    FAS CCNA2 0 0 267 267 1 1
    FAS TLR6 0 0 108 243 1 1
    FAS IL2 0 0 681 700 1 1
    FAS DEDD 0 0 174 174 1 1
    FAS PVR 0 0 214 231 1 1
    FAS CASP1 0 0 520 597 1 2
    FAS NOS1 0 0 112 159 1 1
    FAS ARF6 0 0 0 250 1 1
    FAS CCR3 0 0 193 229 1 1
    FAS HLA-DPA1 0 0 357 369 1 1
    FAS CCL7 0 0 166 181 1 1
    FAS BECN1 0 0 358 358 1 2
    FAS FAM91A1 416 0 0 416 1 1
    FAS MVP 0 0 125 169 1 1
    FAS SDC1 0 0 596 637 1 1
    FAS DNTT 0 0 464 463 1 1
    FAS CHEK1 0 0 234 234 1 1
    FAS CD74 0 0 170 195 1 1
    FAS ABCB1 0 0 277 280 1 1
    FAS THBS1 0 0 181 198 1 1
    FAS CD27 0 0 704 739 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005516 Molecular Function calmodulin binding enables IDA
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0019900 Molecular Function kinase binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0038023 Molecular Function signaling receptor activity enables NAS
    GO:0005031 Molecular Function tumor necrosis factor receptor activity enables IBA
    GO:0005031 Molecular Function tumor necrosis factor receptor activity enables IDA
    GO:0036337 Biological Process Fas signaling pathway involved_in IDA
    GO:0036337 Biological Process Fas signaling pathway involved_in IMP
    GO:0006924 Biological Process activation-induced cell death of T cells involved_in IBA
    GO:0006915 Biological Process apoptotic process acts_upstream_of_or_within IDA
    GO:0034198 Biological Process cellular response to amino acid starvation involved_in IMP
    GO:0071455 Biological Process cellular response to hyperoxia involved_in IMP
    GO:0071260 Biological Process cellular response to mechanical stimulus involved_in IEP
    GO:0097191 Biological Process extrinsic apoptotic signaling pathway involved_in IMP
    GO:0008625 Biological Process extrinsic apoptotic signaling pathway via death domain receptors involved_in IDA
    GO:0006955 Biological Process immune response involved_in IEA
    GO:0097049 Biological Process motor neuron apoptotic process involved_in IBA
    GO:0097527 Biological Process necroptotic signaling pathway involved_in IBA
    GO:0097527 Biological Process necroptotic signaling pathway involved_in IMP
    GO:0043066 Biological Process negative regulation of apoptotic process involved_in IBA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IMP
    GO:2001235 Biological Process positive regulation of apoptotic signaling pathway involved_in IMP
    GO:1903428 Biological Process positive regulation of reactive oxygen species biosynthetic process involved_in IDA
    GO:0065003 Biological Process protein-containing complex assembly involved_in TAS
    GO:0042981 Biological Process regulation of apoptotic process involved_in NAS
    GO:0032872 Biological Process regulation of stress-activated MAPK cascade involved_in IBA
    GO:0032872 Biological Process regulation of stress-activated MAPK cascade involved_in IMP
    GO:0007165 Biological Process signal transduction involved_in TAS
    GO:0033209 Biological Process tumor necrosis factor-mediated signaling pathway involved_in IEA
    GO:0031265 Cellular Component CD95 death-inducing signaling complex part_of IBA
    GO:0031265 Cellular Component CD95 death-inducing signaling complex part_of IDA
    GO:0009986 Cellular Component cell surface located_in IDA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in NAS
    GO:0031264 Cellular Component death-inducing signaling complex part_of IDA
    GO:0009897 Cellular Component external side of plasma membrane is_active_in IBA
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0045121 Cellular Component membrane raft is_active_in IBA
    GO:0045121 Cellular Component membrane raft located_in IDA
    GO:0016604 Cellular Component nuclear body located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in IMP
    GO:0005886 Cellular Component plasma membrane located_in TAS
    Pathways
    Name DB ID
    Apoptosis Reactome R-HSA-109581
    Caspase activation via Death Receptors in the presence of ligand Reactome R-HSA-140534
    Signal Transduction Reactome R-HSA-162582
    Generic Transcription Pathway Reactome R-HSA-212436
    Regulation by c-FLIP Reactome R-HSA-3371378
    Transcriptional Regulation by TP53 Reactome R-HSA-3700989
    RIPK1-mediated regulated necrosis Reactome R-HSA-5213460
    Regulated Necrosis Reactome R-HSA-5218859
    CASP8 activity is inhibited Reactome R-HSA-5218900
    Caspase activation via extrinsic apoptotic signalling pathway Reactome R-HSA-5357769
    Programmed Cell Death Reactome R-HSA-5357801
    TP53 Regulates Transcription of Cell Death Genes Reactome R-HSA-5633008
    Regulation of necroptotic cell death Reactome R-HSA-5675482
    TP53 Regulates Transcription of Death Receptors and Ligands Reactome R-HSA-6803211
    Dimerization of procaspase-8 Reactome R-HSA-69416
    RNA Polymerase II Transcription Reactome R-HSA-73857
    Death Receptor Signaling Reactome R-HSA-73887
    Gene expression (Transcription) Reactome R-HSA-74160
    FasL/ CD95L signaling Reactome R-HSA-75157
    7q11.23 copy number variation syndrome (WP4932) WikiPathways WP4932_r118797
    p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
    Control of immune tolerance by vasoactive intestinal peptide (WP4484) WikiPathways WP4484_r107333
    Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
    Measles virus infection (WP4630) WikiPathways WP4630_r123414
    Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
    Nanomaterial induced apoptosis (WP2507) WikiPathways WP2507_r123897
    Complement system in neuronal development and plasticity (WP5090) WikiPathways WP5090_r118898
    Apoptosis modulation by HSP70 (WP384) WikiPathways WP384_r121706
    Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
    T-cell receptor signaling pathway (WP69) WikiPathways WP69_r120966
    Adipogenesis (WP236) WikiPathways WP236_r105873
    Familial hyperlipidemia type 4 (WP5111) WikiPathways WP5111_r119173
    IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
    MAPK signaling pathway (WP382) WikiPathways WP382_r119087
    Fas ligand pathway and stress induction of heat shock proteins (WP314) WikiPathways WP314_r121827
    Allograft rejection (WP2328) WikiPathways WP2328_r120805
    Circadian rhythm genes (WP3594) WikiPathways WP3594_r117682
    Cell interactions of the pancreatic cancer microenvironment (WP5284) WikiPathways WP5284_r124340
    DNA damage response (WP707) WikiPathways WP707_r124174
    Apoptosis (WP254) WikiPathways WP254_r118382
    Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
    T cell modulation in pancreatic cancer (WP5078) WikiPathways WP5078_r124394
    Photodynamic therapy-induced AP-1 survival signaling (WP3611) WikiPathways WP3611_r120501
    Male infertility (WP4673) WikiPathways WP4673_r119920
    Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
    miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_028036 4 miscRNA transcript variant 7 NC_000010 Reference
    NR_135313 2 miscRNA transcript variant 9 NC_000010 Reference
    NR_028033 4 miscRNA transcript variant 4 NC_000010 Reference
    NR_028035 4 miscRNA transcript variant 6 NC_000010 Reference
    NR_028034 4 miscRNA transcript variant 5 NC_000010 Reference
    NR_135314 2 miscRNA transcript variant 10 NC_000010 Reference
    NR_135315 2 miscRNA transcript variant 11 NC_000010 Reference
    XM_006717819 4 mRNA transcript variant X3 NC_000010 Reference
    XM_011539764 3 mRNA transcript variant X1 NC_000010 Reference
    XM_011539765 3 mRNA transcript variant X2 NC_000010 Reference
    XM_047425179 1 mRNA transcript variant X6 NC_000010 Reference
    XM_047425180 1 mRNA transcript variant X7 NC_000010 Reference
    XM_011539766 3 mRNA transcript variant X4 NC_000010 Reference
    NM_000043 6 mRNA transcript variant 1 NC_000010 Reference
    NM_152872 4 mRNA transcript variant 3 NC_000010 Reference
    NM_001320619 2 mRNA transcript variant 8 NC_000010 Reference
    NM_152871 4 mRNA transcript variant 2 NC_000010 Reference
    NM_001410956 1 mRNA transcript variant 12 NC_000010 Reference
    XM_047425178 1 mRNA transcript variant X5 NC_000010 Reference