PPP1R15A

protein phosphatase 1 regulatory subunit 15A
General Information
Name protein phosphatase 1 regulatory subunit 15A
Alias
  • protein phosphatase 1 regulatory subunit 15A
  • growth arrest and DNA damage-inducible protein GADD34
  • growth arrest and DNA-damage-inducible 34
  • myeloid differentiation primary response protein MyD116 homolog
  • protein phosphatase 1, regulatory (inhibitor) subunit 15A
Synonyms GADD34
Gene_family Protein phosphatase 1 regulatory subunits
organism Homo sapiens
entrez_id 23645
location 19q13.2
transcript_count 1
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]
      Stringdb Protein phosphatase 1 regulatory subunit 15A; Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'
      nextProt Recruits the serine/threonine-protein phosphatase PPP1CA to prevents excessive phosphorylation of the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress (PubMed:26742780, PubMed:26095357). Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1 (PubMed:14718519). May promote apoptosis by inducing p53/TP53 phosphorylation on 'Ser-15' (PubMed:14635196). Plays an essential role in autophagy by tuning translation during starvation, thus enabling lysosomal biogenesis and a sustained autophagic flux (PubMed:32978159). Acts also a viral restriction factor by attenuating HIV-1 replication (PubMed:31778897). Mechanistically, mediates the inhibition of HIV-1 TAR RNA-mediated translation (PubMed:31778897).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    PPP1R15A BioGRID XPO7 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID G3BP1 GeneID BioGRID Affinity Capture-RNA
    PPP1R15A BioGRID PPP1CA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    PPP1R15A BioGRID MDM2 GeneID BioGRID Affinity Capture-Western
    PPP1R15A BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID TBL2 GeneID BioGRID Affinity Capture-RNA
    PPP1R15A BioGRID EIF2S1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    PPP1R15A BioGRID ZNF92 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID PWWP3A GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID PLEKHA1 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID BBX GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID MINK1 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID POLR3A GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID POP4 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID FZR1 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    PPP1R15A BioGRID PLEC GeneID BioGRID Proximity Label-MS
    PPP1R15A BioGRID PPZ1 GeneID BioGRID Reconstituted Complex
    PPP1R15A BioGRID PPP1R1A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    PPP1R15A BioGRID PPP1CC GeneID BioGRID Affinity Capture-Western; Co-purification
    PPP1R15A BioGRID PPP1CB GeneID BioGRID Affinity Capture-Western
    PPP1R15A BioGRID ZNF512B GeneID BioGRID Two-hybrid
    PPP1R15A BioGRID CTBP2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PPP1R15A BioGRID SMAD7 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PPP1R15A BioGRID CAND1 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID COPS5 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    PPP1R15A BioGRID RAD21 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PPP1R15A BioGRID CUEDC2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PPP1R15A BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
    PPP1R15A BioGRID HABP4 GeneID BioGRID Two-hybrid
    PPP1R15A None PPP1R1A GeneID HPRD None
    PPP1R15A None PPP1CA GeneID HPRD None
    PPP1R15A None HABP4 GeneID HPRD None
    PPP1R15A None TSN GeneID HPRD None
    PPP1R15A None KIF3A GeneID HPRD None
    PPP1R15A None EIF2S1 GeneID HPRD None
    PPP1R15A None BCAR1 GeneID HPRD None
    PPP1R15A None POU3F3 GeneID HPRD None
    PPP1R15A None SMARCB1 GeneID HPRD None
    PPP1R15A None BAG1 GeneID HPRD None
    PPP1R15A None LYN GeneID HPRD None
    PPP1R15A None KMT2A GeneID HPRD None
    PPP1R15A None HSPA1A GeneID HPRD None
    PPP1R15A BioGRID TSN GeneID BioGRID Reconstituted Complex; Two-hybrid
    PPP1R15A BioGRID LYN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    PPP1R15A BioGRID BAG1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    PPP1R15A BioGRID BCAR1 GeneID BioGRID Two-hybrid
    PPP1R15A BioGRID GLC7 GeneID BioGRID Two-hybrid
    PPP1R15A BioGRID SMARCB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    PPP1R15A BioGRID KMT2A GeneID BioGRID Affinity Capture-Western; Two-hybrid
    PPP1R15A BioGRID HSPA8 GeneID BioGRID Affinity Capture-Western
    StringDB
    A B experiments database textmining combined score hadb nhadb
    PPP1R15A RPS25 0 0 67 176 1 1
    PPP1R15A NUPR1 0 0 189 219 1 1
    PPP1R15A IER5 0 0 57 152 1 1
    PPP1R15A NGDN 0 0 194 194 1 1
    PPP1R15A SLC2A3 0 0 112 166 1 1
    PPP1R15A MAGEB3 0 0 0 171 1 1
    PPP1R15A CLCN4 0 0 0 206 1 1
    PPP1R15A SMAD4 0 0 178 177 1 1
    PPP1R15A PPP3CC 0 540 0 639 1 1
    PPP1R15A MKNK2 0 0 0 165 1 1
    PPP1R15A GPR78 0 0 323 353 1 1
    PPP1R15A PRSS57 0 0 217 217 1 1
    PPP1R15A EIF5B 0 0 210 264 1 1
    PPP1R15A SSR1 0 0 106 256 1 1
    PPP1R15A CHAC1 0 0 464 490 1 1
    PPP1R15A FKBP7 0 0 76 336 1 1
    PPP1R15A BRCA1 0 0 157 156 1 1
    PPP1R15A OPA1 0 0 46 173 1 1
    PPP1R15A PPIF 0 0 93 162 1 1
    PPP1R15A RB1CC1 0 0 161 161 1 2
    PPP1R15A EIF2B5 0 0 263 278 1 1
    PPP1R15A NFE2L2 0 0 325 325 1 1
    PPP1R15A EIF3G 0 0 155 154 1 1
    PPP1R15A ENSG00000272772 0 0 0 226 1 1
    PPP1R15A BEX2 0 0 164 182 1 1
    PPP1R15A PPP1R1B 0 0 162 181 1 1
    PPP1R15A ANKRD28 0 0 134 164 1 1
    PPP1R15A TAGAP 0 0 161 309 1 1
    PPP1R15A PPARGC1A 0 0 170 169 1 1
    PPP1R15A TREM1 0 0 57 153 1 1
    PPP1R15A MYC 71 0 366 399 1 2
    PPP1R15A PPP1R7 0 0 243 252 1 1
    PPP1R15A CYP51A1 0 0 53 150 1 1
    PPP1R15A WFS1 0 0 370 384 1 1
    PPP1R15A PPP5C 0 0 0 226 1 1
    PPP1R15A IFNA1 0 0 157 156 1 1
    PPP1R15A MAD2L1 0 0 328 328 1 1
    PPP1R15A CBX4 114 0 74 165 1 1
    PPP1R15A ACACA 0 0 165 179 1 1
    PPP1R15A NR4A3 0 0 73 169 1 1
    PPP1R15A MX1 0 0 117 151 1 1
    PPP1R15A TMBIM6 0 0 281 312 1 1
    PPP1R15A P4HB 0 0 457 505 1 2
    PPP1R15A SLC7A1 0 0 174 224 1 1
    PPP1R15A TRAF2 0 0 325 432 1 1
    PPP1R15A RUVBL2 0 0 47 333 1 1
    PPP1R15A PPP1R3C 0 540 123 582 1 1
    PPP1R15A ARHGEF28 0 0 0 218 1 1
    PPP1R15A PPP3CB 0 720 0 775 1 1
    PPP1R15A SRSF1 0 0 293 293 1 1
    PPP1R15A MAFF 0 0 53 322 1 1
    PPP1R15A IL20RB 0 0 155 606 1 1
    PPP1R15A NKD1 0 720 0 720 1 1
    PPP1R15A NR4A1 0 0 156 218 1 1
    PPP1R15A AGR2 0 0 175 175 1 1
    PPP1R15A BRD7 0 0 46 152 1 1
    PPP1R15A CCNI 0 0 66 225 1 1
    PPP1R15A APAF1 0 0 233 239 1 1
    PPP1R15A MKNK1 0 0 105 180 1 1
    PPP1R15A EXOSC10 0 0 44 345 1 1
    PPP1R15A EIF2AK4 0 0 683 787 1 1
    PPP1R15A HBEGF 0 0 0 151 1 1
    PPP1R15A STAT3 0 0 180 197 1 2
    PPP1R15A GAS1 0 0 174 263 1 1
    PPP1R15A PPP1R11 0 0 0 512 1 1
    PPP1R15A ERN1 0 0 754 780 1 2
    PPP1R15A NET1 0 0 0 218 1 1
    PPP1R15A GCLM 0 0 174 175 1 1
    PPP1R15A SERPINH1 0 0 170 181 1 1
    PPP1R15A DECR1 0 0 0 303 1 1
    PPP1R15A FADD 0 0 206 206 1 2
    PPP1R15A PPP1CC 487 720 988 998 1 1
    PPP1R15A HTT 0 0 243 256 1 1
    PPP1R15A EGFR 0 0 181 181 1 1
    PPP1R15A CFLAR 0 0 170 175 1 1
    PPP1R15A TIMM50 114 0 0 264 1 1
    PPP1R15A TP53 114 0 622 651 1 2
    PPP1R15A MDM2 0 0 155 173 1 1
    PPP1R15A HMGCS1 0 0 96 161 1 1
    PPP1R15A INSIG1 0 0 165 165 1 1
    PPP1R15A SLC7A5 0 0 156 155 1 1
    PPP1R15A PPP2R5D 0 540 45 541 1 1
    PPP1R15A DDIT3 0 0 825 864 1 2
    PPP1R15A MAP3K7 0 0 150 203 1 1
    PPP1R15A NFKBIZ 0 0 146 231 1 1
    PPP1R15A DNAJA1 0 0 118 158 1 1
    PPP1R15A PABPC1 0 0 179 216 1 1
    PPP1R15A ZFAND1 0 0 0 248 1 1
    PPP1R15A GZMH 0 0 61 317 1 1
    PPP1R15A TRAF1 0 0 66 293 1 1
    PPP1R15A MRPL43 0 0 0 167 1 1
    PPP1R15A MTOR 0 0 360 360 1 2
    PPP1R15A CYR61 0 0 123 187 1 1
    PPP1R15A CTAG1A 0 0 413 412 1 1
    PPP1R15A CRELD2 0 0 134 153 1 1
    PPP1R15A THEMIS 0 0 81 170 1 1
    PPP1R15A SEC61A1 0 0 193 193 1 1
    PPP1R15A STAT1 0 0 167 167 1 1
    PPP1R15A DNAJB4 114 0 142 213 1 1
    PPP1R15A HFE2 0 900 0 900 1 1
    PPP1R15A SYVN1 0 0 244 273 1 1
    PPP1R15A TNFRSF1A 0 0 151 150 1 1
    PPP1R15A GZMB 0 0 66 210 1 1
    PPP1R15A RPS6 0 0 241 254 1 1
    PPP1R15A PLIN1 0 0 75 171 1 1
    PPP1R15A PIK3C3 0 0 397 396 1 2
    PPP1R15A SERTAD1 0 0 155 199 1 1
    PPP1R15A PPP4C 0 360 49 621 1 1
    PPP1R15A RAB12 0 0 51 214 1 2
    PPP1R15A UCP2 0 0 102 166 1 1
    PPP1R15A PPP1R12A 0 720 180 781 1 1
    PPP1R15A MPZ 0 0 261 261 1 1
    PPP1R15A IL6 0 0 310 343 1 1
    PPP1R15A SRSF9 0 0 412 412 1 1
    PPP1R15A SCAF11 0 0 261 261 1 1
    PPP1R15A CXCL8 0 0 261 342 1 1
    PPP1R15A PPP2R2D 0 720 87 762 1 1
    PPP1R15A BEX1 0 0 161 179 1 1
    PPP1R15A OTUD3 0 0 64 309 1 1
    PPP1R15A SLC1A7 0 0 184 201 1 1
    PPP1R15A NEDD4 0 0 45 332 1 2
    PPP1R15A GCK 0 0 161 161 1 1
    PPP1R15A HIF1A 0 0 242 241 1 2
    PPP1R15A BAG3 0 0 181 239 1 2
    PPP1R15A RPL12 0 0 45 151 1 1
    PPP1R15A IL1B 0 0 272 318 1 1
    PPP1R15A ZBTB43 0 0 181 191 1 1
    PPP1R15A EDEM3 0 0 150 181 1 1
    PPP1R15A KIF3B 0 0 385 426 1 1
    PPP1R15A IBTK 0 0 171 171 1 1
    PPP1R15A PSAT1 0 0 137 156 1 1
    PPP1R15A ARC 0 0 139 192 1 1
    PPP1R15A HRAS 0 0 181 181 1 1
    PPP1R15A PPP1R14C 0 0 171 171 1 1
    PPP1R15A EGR1 0 0 241 355 1 1
    PPP1R15A APP 0 0 183 183 1 1
    PPP1R15A NFKB1 0 0 154 198 1 1
    PPP1R15A KLF6 0 0 236 474 1 1
    PPP1R15A BCL2L1 0 0 323 337 1 2
    PPP1R15A RELA 0 0 113 170 1 1
    PPP1R15A ME1 0 0 58 153 1 1
    PPP1R15A PIK3R4 0 0 433 433 1 2
    PPP1R15A MMP26 0 0 48 436 1 1
    PPP1R15A XPOT 114 0 113 182 1 1
    PPP1R15A NABP1 0 0 97 153 1 1
    PPP1R15A RGMB 0 900 0 900 1 1
    PPP1R15A MYADM 0 0 203 340 1 1
    PPP1R15A MAP2K7 0 0 156 155 1 1
    PPP1R15A TNFAIP8L1 0 0 61 207 1 1
    PPP1R15A SH2B3 0 0 113 270 1 1
    PPP1R15A PPP1R3E 0 540 0 556 1 1
    PPP1R15A NMNAT1 0 0 0 302 1 1
    PPP1R15A TLR4 0 0 207 207 1 1
    PPP1R15A SMAD2 0 0 203 218 1 1
    PPP1R15A DUSP5 0 0 284 357 1 1
    PPP1R15A ELOVL5 0 0 71 212 1 1
    PPP1R15A GAPDH 0 0 414 414 1 2
    PPP1R15A EGR3 0 0 94 187 1 1
    PPP1R15A ATG14 0 0 442 442 1 2
    PPP1R15A ZFYVE16 0 900 122 914 1 1
    PPP1R15A SERP1 0 0 218 218 1 1
    PPP1R15A USP44 0 0 0 207 1 1
    PPP1R15A WWP1 0 0 144 209 1 1
    PPP1R15A IFNG 0 0 123 177 1 2
    PPP1R15A COX5A 0 0 45 153 1 1
    PPP1R15A CREB1 0 0 308 307 1 1
    PPP1R15A CIDEC 0 0 57 202 1 1
    PPP1R15A MUM1 229 0 0 228 1 1
    PPP1R15A TGFB3 0 900 49 900 1 1
    PPP1R15A ZNF563 0 0 193 372 1 1
    PPP1R15A PFKFB3 0 0 60 170 1 1
    PPP1R15A PPP2R2A 114 720 71 792 1 1
    PPP1R15A SC5D 0 0 123 216 1 1
    PPP1R15A ATF5 0 0 505 562 1 1
    PPP1R15A HSF1 0 0 100 152 1 1
    PPP1R15A FGF21 0 0 185 185 1 1
    PPP1R15A CCNB1 0 0 170 183 1 1
    PPP1R15A ANXA5 0 0 288 293 1 1
    PPP1R15A HSPD1 0 0 94 187 1 1
    PPP1R15A MGMT 0 0 103 164 1 1
    PPP1R15A SKA2 0 0 150 381 1 1
    PPP1R15A TFAM 0 0 202 293 1 1
    PPP1R15A CREB3 0 0 235 235 1 1
    PPP1R15A KLHDC3 0 0 86 187 1 1
    PPP1R15A ATP5B 114 0 72 175 1 1
    PPP1R15A EIF2AK2 0 0 384 734 1 2
    PPP1R15A OR5I1 0 0 55 156 1 1
    PPP1R15A SMAD1 0 900 87 906 1 1
    PPP1R15A CALR 0 0 536 546 1 1
    PPP1R15A BIK 0 0 232 231 1 1
    PPP1R15A KIF3C 0 0 397 437 1 1
    PPP1R15A DNAJC3 0 0 681 728 1 1
    PPP1R15A SOD1 0 0 310 337 1 1
    PPP1R15A ELOVL6 0 0 125 371 1 1
    PPP1R15A EIF1 0 0 487 526 1 1
    PPP1R15A ERN2 0 0 508 549 1 1
    PPP1R15A ANGPTL6 0 0 123 151 1 1
    PPP1R15A VCP 0 0 166 183 1 2
    PPP1R15A CREB3L2 0 0 325 334 1 1
    PPP1R15A ITPR3 0 0 322 326 1 1
    PPP1R15A JUN 0 0 469 671 1 1
    PPP1R15A MAN2A1 0 0 0 188 1 1
    PPP1R15A ARID5A 0 0 90 202 1 1
    PPP1R15A CTDSP2 0 0 49 225 1 1
    PPP1R15A BCL2L11 0 0 530 540 1 1
    PPP1R15A TSC1 0 0 450 488 1 2
    PPP1R15A NRF1 0 0 432 432 1 1
    PPP1R15A MTHFD2 0 0 170 198 1 1
    PPP1R15A PTCRA 0 0 0 157 1 1
    PPP1R15A DNAJA3 114 0 64 155 1 1
    PPP1R15A ZFP36 0 0 82 581 1 1
    PPP1R15A HSPA1A 213 0 358 496 1 1
    PPP1R15A CNEP1R1 0 720 0 720 1 1
    PPP1R15A SH2D3C 0 0 181 181 1 1
    PPP1R15A CCDC168 0 0 123 660 1 1
    PPP1R15A CHEK1 114 0 166 231 1 1
    PPP1R15A DNTT 0 0 194 194 1 1
    PPP1R15A SNCA 0 0 182 181 1 2
    PPP1R15A CASP1 0 0 184 213 1 2
    PPP1R15A EIF2AK1 0 650 603 880 1 1
    PPP1R15A DAZAP1 0 0 0 187 1 1
    PPP1R15A BNIP3 0 0 171 171 1 2
    PPP1R15A SQSTM1 0 0 260 293 1 2
    PPP1R15A SLC11A2 0 0 0 206 1 1
    PPP1R15A JUNB 0 0 66 391 1 1
    PPP1R15A INHBE 0 0 112 206 1 1
    PPP1R15A CSNK1E 0 0 363 363 1 1
    PPP1R15A MAPK3 0 0 202 251 1 2
    PPP1R15A B2M 0 0 155 176 1 1
    PPP1R15A KEAP1 114 0 171 259 1 2
    PPP1R15A GTSE1 114 0 96 164 1 1
    PPP1R15A GLP1R 0 0 134 168 1 1
    PPP1R15A STUB1 0 0 150 189 1 2
    PPP1R15A EDEM2 0 0 287 316 1 1
    PPP1R15A TCEAL1 0 0 181 181 1 1
    PPP1R15A ACTB 114 0 430 489 1 1
    PPP1R15A ATG13 0 0 155 156 1 2
    PPP1R15A INS 0 0 380 380 1 1
    PPP1R15A PLEKHA1 229 0 0 228 1 1
    PPP1R15A DNAJA4 0 0 184 268 1 1
    PPP1R15A CEBPA 0 0 262 344 1 1
    PPP1R15A WDR82 0 720 0 720 1 1
    PPP1R15A HSP90AA1 0 0 345 346 1 2
    PPP1R15A CREB3L1 0 0 253 252 1 1
    PPP1R15A FOSL1 0 0 150 359 1 1
    PPP1R15A GABARAPL1 0 0 134 152 1 2
    PPP1R15A PDK2 0 0 574 574 1 1
    PPP1R15A CTAG1B 0 0 399 398 1 1
    PPP1R15A ENSG00000269590 0 0 0 189 1 1
    PPP1R15A ELOVL3 0 0 62 158 1 1
    PPP1R15A PPP1R3D 0 540 0 578 1 1
    PPP1R15A RAB11FIP1 0 0 46 260 1 1
    PPP1R15A SLC38A2 0 0 220 250 1 1
    PPP1R15A GABPB1 0 0 112 151 1 1
    PPP1R15A BAX 0 0 185 191 1 2
    PPP1R15A TARDBP 114 0 228 339 1 1
    PPP1R15A EIF5 0 0 294 306 1 1
    PPP1R15A PARP1 114 0 146 238 1 2
    PPP1R15A EIF4G1 0 0 343 358 1 2
    PPP1R15A CDCA7 0 0 87 156 1 1
    PPP1R15A CRTC2 0 0 134 153 1 1
    PPP1R15A HSPA8 299 0 248 474 1 2
    PPP1R15A ERP44 0 0 219 219 1 1
    PPP1R15A CDKN1A 0 0 307 364 1 2
    PPP1R15A OSGIN1 0 0 171 222 1 1
    PPP1R15A TRIM21 0 0 329 329 1 1
    PPP1R15A MB21D1 0 0 135 198 1 1
    PPP1R15A HMX1 0 0 193 193 1 1
    PPP1R15A HYOU1 0 0 406 409 1 1
    PPP1R15A DUSP8 0 0 108 182 1 1
    PPP1R15A DDX58 0 0 228 227 1 1
    PPP1R15A ATP2A1 0 0 117 157 1 1
    PPP1R15A MAVS 0 0 166 165 1 1
    PPP1R15A MAP1LC3C 0 0 139 157 1 2
    PPP1R15A TOX4 0 720 0 731 1 1
    PPP1R15A PPP1CB 299 720 540 940 1 1
    PPP1R15A PNO1 0 0 71 377 1 1
    PPP1R15A SLC3A2 0 0 138 188 1 1
    PPP1R15A NFIL3 0 0 67 153 1 1
    PPP1R15A PPP2R5A 0 720 49 722 1 1
    PPP1R15A ARHGEF40 0 0 161 345 1 1
    PPP1R15A HERPUD1 0 0 469 524 1 1
    PPP1R15A CASP7 0 0 273 283 1 1
    PPP1R15A CREB3L3 0 0 456 456 1 1
    PPP1R15A EIF4A1 0 0 310 323 1 1
    PPP1R15A CASP8 0 0 322 326 1 2
    PPP1R15A PPM1G 0 0 482 482 1 1
    PPP1R15A ALB 0 0 265 285 1 1
    PPP1R15A CCL2 0 0 175 175 1 2
    PPP1R15A PPP2R1B 0 540 0 553 1 1
    PPP1R15A BIRC3 0 0 159 194 1 1
    PPP1R15A SMAD3 0 0 155 198 1 1
    PPP1R15A ERO1L 0 0 684 686 1 1
    PPP1R15A PPEF1 0 0 95 270 1 1
    PPP1R15A SIRPA 0 0 390 390 1 1
    PPP1R15A SLC30A1 0 0 181 191 1 1
    PPP1R15A CCDC70 0 0 173 179 1 1
    PPP1R15A EGF 0 0 164 163 1 1
    PPP1R15A BMP2 0 900 45 900 1 1
    PPP1R15A HGSNAT 0 0 103 303 1 1
    PPP1R15A WBP1 0 0 203 220 1 1
    PPP1R15A PROC 0 0 46 217 1 1
    PPP1R15A RGMA 0 900 0 900 1 1
    PPP1R15A SPATA3 0 0 112 473 1 1
    PPP1R15A FASN 0 0 204 204 1 1
    PPP1R15A ITPR1 0 360 340 562 1 2
    PPP1R15A CASP9 0 0 345 349 1 1
    PPP1R15A TRAF6 0 0 491 590 1 2
    PPP1R15A SQLE 0 0 108 173 1 1
    PPP1R15A CHEK2 0 0 150 169 1 1
    PPP1R15A GADD45B 0 0 405 584 1 1
    PPP1R15A DUSP12 0 0 342 342 1 1
    PPP1R15A MAN2B2 0 0 0 250 1 1
    PPP1R15A CYCS 0 720 390 821 1 1
    PPP1R15A SHOC2 0 720 0 720 1 1
    PPP1R15A MAPK9 0 0 156 237 1 2
    PPP1R15A HSP90B1 0 0 654 672 1 1
    PPP1R15A CEBPD 0 0 108 174 1 1
    PPP1R15A TRA2B 0 0 354 354 1 1
    PPP1R15A NES 0 0 103 155 1 1
    PPP1R15A RPTOR 0 0 139 154 1 2
    PPP1R15A CSDE1 0 0 66 220 1 1
    PPP1R15A HSPB3 0 0 160 159 1 1
    PPP1R15A PPP4R2 0 720 45 721 1 1
    PPP1R15A PPARA 0 0 193 193 1 1
    PPP1R15A TRIB1 0 0 74 240 1 1
    PPP1R15A IER3 0 0 211 258 1 1
    PPP1R15A HSPA4 0 0 391 394 1 1
    PPP1R15A PCBP2 0 0 150 235 1 1
    PPP1R15A ICE1 0 0 74 242 1 1
    PPP1R15A RDX 0 0 49 168 1 1
    PPP1R15A PLAUR 0 0 59 151 1 1
    PPP1R15A PPP1R10 0 720 370 847 1 1
    PPP1R15A C3orf67 0 0 127 212 1 1
    PPP1R15A RPS6KB2 0 0 82 158 1 2
    PPP1R15A PPP2R5B 0 540 0 540 1 1
    PPP1R15A MBTPS2 0 0 451 463 1 1
    PPP1R15A PPP2CB 0 720 62 779 1 1
    PPP1R15A FKBP1A 0 0 148 163 1 2
    PPP1R15A SMARCB1 486 0 614 793 1 1
    PPP1R15A PRNP 0 0 181 207 1 1
    PPP1R15A CLDN11 0 0 140 218 1 1
    PPP1R15A SESN2 0 0 219 244 1 2
    PPP1R15A IFIH1 0 0 193 211 1 1
    PPP1R15A PSMD11 114 0 74 171 1 1
    PPP1R15A HBZ 0 0 882 888 1 1
    PPP1R15A ARHGEF3 0 0 0 218 1 1
    PPP1R15A HSPA6 0 0 195 248 1 1
    PPP1R15A DIABLO 0 0 150 182 1 1
    PPP1R15A UBALD2 0 0 145 202 1 1
    PPP1R15A SPCS2 0 0 103 347 1 1
    PPP1R15A PHLDA1 0 0 205 240 1 1
    PPP1R15A VPS33A 0 0 66 360 1 1
    PPP1R15A EIF2S2 0 900 378 938 1 1
    PPP1R15A BHLHE40 0 0 143 257 1 1
    PPP1R15A NMNAT3 0 0 73 627 1 1
    PPP1R15A RUVBL1 114 0 71 195 1 1
    PPP1R15A TCP11L1 0 0 162 213 1 1
    PPP1R15A MAPK8 0 0 265 400 1 2
    PPP1R15A SUMO3 0 0 407 407 1 1
    PPP1R15A GCLC 0 0 230 229 1 1
    PPP1R15A TNFAIP3 0 0 247 358 1 1
    PPP1R15A GCG 0 0 170 169 1 1
    PPP1R15A C10orf10 0 0 60 204 1 1
    PPP1R15A NFKB2 0 0 81 171 1 1
    PPP1R15A EDEM1 0 0 638 644 1 2
    PPP1R15A KMT2A 270 0 579 680 1 1
    PPP1R15A SRSF2 0 0 0 200 1 1
    PPP1R15A TXNIP 0 0 294 314 1 1
    PPP1R15A BCL2A1 0 0 112 151 1 1
    PPP1R15A ADM2 0 0 95 330 1 1
    PPP1R15A ITSN2 0 0 46 610 1 1
    PPP1R15A SLC17A9 0 0 57 562 1 1
    PPP1R15A RELB 0 0 96 150 1 2
    PPP1R15A PPEF2 0 0 0 240 1 1
    PPP1R15A USP26 0 0 0 157 1 1
    PPP1R15A SDF2L1 0 0 144 202 1 1
    PPP1R15A BCAP31 0 0 175 231 1 1
    PPP1R15A THRSP 0 0 72 235 1 1
    PPP1R15A ENSG00000164096 0 0 160 159 1 1
    PPP1R15A G3BP1 0 0 352 352 1 1
    PPP1R15A PPP2R5C 0 720 76 730 1 1
    PPP1R15A ATF3 0 0 653 872 1 1
    PPP1R15A CEP290 114 0 307 359 1 1
    PPP1R15A GADD45A 0 0 558 594 1 1
    PPP1R15A MINK1 257 0 56 296 1 1
    PPP1R15A NEDD4L 0 0 113 269 1 1
    PPP1R15A DDX53 0 0 648 648 1 1
    PPP1R15A PPP2R2B 0 540 0 568 1 1
    PPP1R15A UVRAG 0 0 442 442 1 2
    PPP1R15A IGF1 0 0 150 168 1 1
    PPP1R15A PPP2R1A 114 720 0 749 1 1
    PPP1R15A IRF7 0 0 141 184 1 1
    PPP1R15A HSPA2 114 0 0 187 1 1
    PPP1R15A C22orf29 0 0 258 258 1 1
    PPP1R15A HNRNPD 0 0 306 306 1 1
    PPP1R15A TANK 0 0 117 175 1 1
    PPP1R15A RNF4 0 0 51 196 1 1
    PPP1R15A TNF 0 0 317 356 1 1
    PPP1R15A C6orf47 0 0 234 234 1 1
    PPP1R15A CASP2 0 0 260 292 1 1
    PPP1R15A IP6K3 0 0 143 203 1 1
    PPP1R15A NR4A2 0 0 90 194 1 1
    PPP1R15A DDX17 0 0 71 167 1 1
    PPP1R15A RCAN1 0 0 112 167 1 2
    PPP1R15A TCP11 0 0 0 195 1 1
    PPP1R15A EEF2 114 0 260 316 1 1
    PPP1R15A PPP1R2 0 0 134 171 1 1
    PPP1R15A DDX3X 114 0 108 175 1 1
    PPP1R15A USP14 0 0 120 160 1 1
    PPP1R15A RPLP0 0 0 179 244 1 1
    PPP1R15A SLC7A11 0 0 232 231 1 1
    PPP1R15A PPP1R3G 0 540 0 540 1 1
    PPP1R15A ATP2A2 0 0 113 153 1 1
    PPP1R15A DFFA 0 0 0 154 1 1
    PPP1R15A LDLR 0 0 89 154 1 1
    PPP1R15A GNB2L1 0 0 174 173 1 1
    PPP1R15A PPP2R3A 0 720 0 720 1 1
    PPP1R15A CAPRIN1 0 0 203 203 1 1
    PPP1R15A PPP2R5E 0 540 0 540 1 1
    PPP1R15A AVEN 0 0 81 255 1 1
    PPP1R15A BAK1 0 0 212 229 1 2
    PPP1R15A IFRD1 0 0 211 304 1 1
    PPP1R15A HPRT1 0 0 151 172 1 1
    PPP1R15A RNASEL 0 0 234 234 1 1
    PPP1R15A AARS 0 0 108 201 1 1
    PPP1R15A DDIT4 0 0 348 381 1 1
    PPP1R15A RHEB 0 0 166 202 1 2
    PPP1R15A UBFD1 0 0 124 166 1 1
    PPP1R15A ITSN1 0 0 49 550 1 1
    PPP1R15A CANX 0 0 460 461 1 2
    PPP1R15A GRIA1 0 0 277 277 1 1
    PPP1R15A TXN 0 0 163 163 1 1
    PPP1R15A BMPR2 0 900 112 908 1 1
    PPP1R15A ZFYVE9 0 900 357 939 1 1
    PPP1R15A HRK 0 0 152 151 1 1
    PPP1R15A S100A10 0 0 140 329 1 1
    PPP1R15A HTRA4 0 0 147 166 1 1
    PPP1R15A CAT 0 0 193 193 1 1
    PPP1R15A PRKDC 0 0 142 160 1 2
    PPP1R15A PPP2CA 0 720 100 788 1 1
    PPP1R15A CDK1 0 0 150 168 1 1
    PPP1R15A EIF4E 0 0 390 409 1 1
    PPP1R15A RPS6KB1 0 0 261 322 1 2
    PPP1R15A TNFAIP8 0 0 49 197 1 1
    PPP1R15A EGR2 0 0 180 246 1 1
    PPP1R15A HSPA9 114 0 176 243 1 1
    PPP1R15A IRS1 0 0 234 234 1 1
    PPP1R15A MEGF10 0 0 44 331 1 1
    PPP1R15A JUND 0 0 95 210 1 1
    PPP1R15A VPS37B 0 0 89 202 1 1
    PPP1R15A CCND1 0 0 265 265 1 1
    PPP1R15A PPP1R3B 0 540 42 550 1 1
    PPP1R15A SREBF2 0 0 167 167 1 1
    PPP1R15A FOXO3 0 0 181 182 1 2
    PPP1R15A DGAT2 0 0 120 175 1 1
    PPP1R15A CD47 0 0 328 328 1 1
    PPP1R15A CREB5 0 0 89 255 1 1
    PPP1R15A SMURF2 0 0 181 243 1 1
    PPP1R15A SCD 0 0 262 262 1 1
    PPP1R15A VIMP 0 0 155 154 1 1
    PPP1R15A SRC 0 0 166 165 1 1
    PPP1R15A DNAJB1 0 0 323 362 1 2
    PPP1R15A DNAJB11 0 0 324 323 1 1
    PPP1R15A HARS2 0 0 96 158 1 1
    PPP1R15A TRIM28 114 0 0 153 1 2
    PPP1R15A TP53INP1 0 0 181 181 1 2
    PPP1R15A ACLY 0 0 155 177 1 1
    PPP1R15A SRXN1 0 0 113 155 1 1
    PPP1R15A EIF2AK3 0 0 706 757 1 2
    PPP1R15A PPP4R1 0 720 46 729 1 1
    PPP1R15A PNP 0 0 74 185 1 1
    PPP1R15A GOLM1 0 0 0 186 1 1
    PPP1R15A TBK1 0 0 160 159 1 2
    PPP1R15A PPP1R18 0 0 159 201 1 1
    PPP1R15A HMOX1 0 0 293 308 1 2
    PPP1R15A FASTKD3 0 0 96 186 1 1
    PPP1R15A GPR89B 0 0 67 267 1 1
    PPP1R15A SRSF8 0 0 0 200 1 1
    PPP1R15A TMEM205 0 0 88 285 1 1
    PPP1R15A EIF2S1 299 900 890 994 1 2
    PPP1R15A WASF1 0 0 292 292 1 1
    PPP1R15A ATF6B 0 0 87 331 1 1
    PPP1R15A MBD5 0 0 55 228 1 1
    PPP1R15A TGFB1 0 900 46 905 1 1
    PPP1R15A GADD45G 0 0 295 311 1 1
    PPP1R15A CUEDC2 270 0 698 770 1 1
    PPP1R15A TSC2 0 0 289 333 1 2
    PPP1R15A LY6K 0 0 55 217 1 1
    PPP1R15A PPP2R3B 0 720 0 720 1 1
    PPP1R15A ERP29 0 0 143 179 1 1
    PPP1R15A PPARG 0 0 234 234 1 1
    PPP1R15A PPP1R9B 0 720 391 844 1 1
    PPP1R15A AKT1 0 0 400 421 1 2
    PPP1R15A MXD1 0 0 104 173 1 1
    PPP1R15A ATF4 0 800 758 964 1 2
    PPP1R15A DERL2 0 0 185 196 1 1
    PPP1R15A HSPH1 114 0 74 167 1 1
    PPP1R15A MBTPS1 0 0 456 456 1 1
    PPP1R15A KLF4 0 0 123 203 1 1
    PPP1R15A HAS3 0 0 120 151 1 1
    PPP1R15A IKBKB 270 0 148 351 1 1
    PPP1R15A ATF6 0 0 759 841 1 2
    PPP1R15A NARS 0 0 147 237 1 1
    PPP1R15A CREB3L4 114 0 234 292 1 1
    PPP1R15A MTMR4 0 0 150 169 1 1
    PPP1R15A VMP1 0 0 150 281 1 2
    PPP1R15A CEBPG 0 0 0 265 1 1
    PPP1R15A TMEM74 0 0 210 210 1 2
    PPP1R15A EDF1 0 0 57 467 1 1
    PPP1R15A PPP2R4 0 720 237 777 1 1
    PPP1R15A ASNS 0 0 509 561 1 1
    PPP1R15A XIAP 0 0 241 271 1 1
    PPP1R15A NOX4 0 0 785 785 1 1
    PPP1R15A PPP3CA 0 720 0 775 1 1
    PPP1R15A IL24 0 0 295 311 1 2
    PPP1R15A IFNGR2 0 0 0 209 1 1
    PPP1R15A PCNXL4 0 0 204 284 1 1
    PPP1R15A MAFG 0 0 82 153 1 1
    PPP1R15A EIF4EBP1 0 0 391 423 1 1
    PPP1R15A PABPC4 114 0 0 154 1 1
    PPP1R15A ASPG 0 0 149 167 1 1
    PPP1R15A AHSA1 0 0 52 199 1 1
    PPP1R15A YME1L1 114 0 75 167 1 1
    PPP1R15A MAFK 0 0 0 185 1 1
    PPP1R15A TSN 270 0 462 590 1 1
    PPP1R15A KCNJ1 0 0 0 188 1 1
    PPP1R15A BBC3 0 0 324 343 1 1
    PPP1R15A BCAT1 0 0 83 174 1 1
    PPP1R15A IRF3 0 0 203 203 1 1
    PPP1R15A FBF1 0 0 60 316 1 1
    PPP1R15A KRAS 0 0 134 176 1 1
    PPP1R15A FOXO1 0 0 213 213 1 2
    PPP1R15A SOD2 0 0 148 166 1 1
    PPP1R15A HSPA5 114 0 755 833 1 2
    PPP1R15A UPF1 0 0 101 260 1 1
    PPP1R15A EIF4A2 0 0 320 333 1 1
    PPP1R15A CSRNP1 0 0 212 425 1 1
    PPP1R15A EMR3 0 0 85 181 1 1
    PPP1R15A PPP1R1A 270 0 438 666 1 1
    PPP1R15A FOS 0 0 294 446 1 1
    PPP1R15A MAN2B1 0 0 0 207 1 1
    PPP1R15A PTK6 0 0 134 660 1 1
    PPP1R15A PPP1R3F 0 540 0 540 1 1
    PPP1R15A EIF3B 114 0 143 241 1 1
    PPP1R15A SOCS3 0 0 108 162 1 1
    PPP1R15A PPP1R3A 0 540 240 635 1 1
    PPP1R15A CTDNEP1 0 720 155 773 1 1
    PPP1R15A PDIA3 0 0 391 420 1 1
    PPP1R15A DNAJB9 0 0 634 639 1 2
    PPP1R15A MAN2A2 0 0 0 250 1 1
    PPP1R15A GRID2 0 0 431 431 1 2
    PPP1R15A EIF2S3 114 900 193 922 1 1
    PPP1R15A ERRFI1 0 0 143 176 1 1
    PPP1R15A SEC62 114 0 81 162 1 1
    PPP1R15A DNAJC10 0 0 180 179 1 1
    PPP1R15A SLC25A28 0 0 67 165 1 1
    PPP1R15A PMAIP1 0 0 459 459 1 1
    PPP1R15A DUSP1 0 0 325 534 1 1
    PPP1R15A MAPK11 0 0 61 223 1 1
    PPP1R15A WARS 0 0 211 226 1 1
    PPP1R15A CCDC22 0 0 58 216 1 1
    PPP1R15A MAGEB10 0 0 183 365 1 1
    PPP1R15A NUAK2 0 0 160 174 1 1
    PPP1R15A AKIRIN2 0 0 95 151 1 1
    PPP1R15A BECN1 0 0 505 513 1 2
    PPP1R15A EIF4EBP2 0 0 107 238 1 1
    PPP1R15A USP49 0 0 88 452 1 1
    PPP1R15A EEF2K 0 0 134 157 1 2
    PPP1R15A DERL1 0 0 122 154 1 1
    PPP1R15A HARS 0 0 112 173 1 1
    PPP1R15A CYBB 0 0 161 161 1 1
    PPP1R15A TIPARP 0 0 112 254 1 1
    PPP1R15A SMUG1 0 0 49 150 1 1
    PPP1R15A ISYNA1 0 0 52 150 1 1
    PPP1R15A HSPA4L 0 0 122 185 1 1
    PPP1R15A ATG12 0 0 240 241 1 2
    PPP1R15A TNFRSF10B 0 0 507 526 1 1
    PPP1R15A EIF4B 0 0 181 208 1 1
    PPP1R15A PRELID1 0 0 0 194 1 1
    PPP1R15A SMURF1 0 0 170 233 1 1
    PPP1R15A PTGS2 0 0 180 264 1 1
    PPP1R15A NQO1 0 0 218 218 1 1
    PPP1R15A CASP3 0 0 505 523 1 2
    PPP1R15A PDIA6 0 0 324 323 1 1
    PPP1R15A TRIB3 0 0 616 636 1 1
    PPP1R15A CDCA2 0 0 182 181 1 1
    PPP1R15A NLRP3 0 0 134 158 1 2
    PPP1R15A HSPA1B 114 0 265 351 1 1
    PPP1R15A PPIC 0 0 687 687 1 1
    PPP1R15A ERO1LB 0 0 371 375 1 1
    PPP1R15A ERCC5 0 0 143 220 1 1
    PPP1R15A NOM1 114 0 81 150 1 1
    PPP1R15A HABP4 192 0 67 213 1 1
    PPP1R15A RIPK1 0 0 138 167 1 1
    PPP1R15A PDIA4 0 0 502 523 1 1
    PPP1R15A TXNRD1 0 0 158 159 1 1
    PPP1R15A ATG16L1 0 0 186 186 1 2
    PPP1R15A CEBPB 0 0 338 438 1 1
    PPP1R15A OLA1 0 0 69 207 1 1
    PPP1R15A FBXO17 0 0 67 189 1 1
    PPP1R15A DUSP2 0 0 108 190 1 1
    PPP1R15A SLC35A4 0 0 213 213 1 1
    PPP1R15A ERCC1 0 0 308 307 1 1
    PPP1R15A PPP6C 0 0 272 413 1 1
    PPP1R15A CASP4 0 0 370 396 1 2
    PPP1R15A BMPR1B 0 900 0 900 1 1
    PPP1R15A ARRB2 0 0 57 156 1 1
    PPP1R15A RPS27A 114 0 0 181 1 1
    PPP1R15A CCNG1 0 0 86 160 1 1
    PPP1R15A ARRB1 0 0 326 325 1 1
    PPP1R15A CALHM2 0 0 95 156 1 1
    PPP1R15A C2orf42 0 0 213 231 1 1
    PPP1R15A ZFAND2A 0 0 150 356 1 1
    PPP1R15A PPP4R4 0 720 61 746 1 1
    PPP1R15A EIF3F 114 0 103 187 1 1
    PPP1R15A CLCN3 0 0 141 375 1 1
    PPP1R15A ATM 0 0 202 202 1 1
    PPP1R15A TGFBR2 0 900 54 903 1 1
    PPP1R15A FOSB 0 0 261 659 1 1
    PPP1R15A ATG7 0 0 327 327 1 2
    PPP1R15A PPP1R15B 0 720 777 823 1 1
    PPP1R15A FOSL2 0 0 72 186 1 1
    PPP1R15A GDF15 0 0 248 310 1 1
    PPP1R15A BTG2 0 0 212 481 1 1
    PPP1R15A NCK1 0 720 108 743 1 1
    PPP1R15A ABCE1 114 0 96 249 1 1
    PPP1R15A PPP3R1 0 720 0 723 1 1
    PPP1R15A CXCL2 0 0 134 204 1 1
    PPP1R15A DERL3 0 0 378 378 1 1
    PPP1R15A VEGFA 0 0 209 209 1 1
    PPP1R15A ARID2 0 0 0 155 1 1
    PPP1R15A PVRL1 0 0 130 212 1 1
    PPP1R15A TRAFD1 114 0 0 187 1 1
    PPP1R15A BMPR1A 0 900 0 900 1 1
    PPP1R15A PTEN 0 0 150 168 1 2
    PPP1R15A DECR2 0 0 66 640 1 1
    PPP1R15A KIAA0226 0 0 457 457 1 1
    PPP1R15A ZC3H12A 0 0 107 215 1 1
    PPP1R15A BMP4 0 900 54 901 1 1
    PPP1R15A TCF4 0 0 209 209 1 1
    PPP1R15A PPP1R9A 0 0 71 164 1 1
    PPP1R15A NFE2L1 0 0 140 205 1 1
    PPP1R15A NFKBIA 0 0 263 367 1 1
    PPP1R15A RTCB 0 0 189 189 1 1
    PPP1R15A PPP1R8 0 0 287 339 1 1
    PPP1R15A MAPK14 0 0 170 395 1 1
    PPP1R15A MAPK10 0 0 113 205 1 2
    PPP1R15A BAG1 270 0 215 402 1 2
    PPP1R15A TP53BP2 0 0 193 198 1 1
    PPP1R15A SREBF1 0 0 294 294 1 2
    PPP1R15A GPR89A 0 0 68 268 1 1
    PPP1R15A KIF3A 213 0 553 675 1 1
    PPP1R15A IER2 0 0 113 257 1 1
    PPP1R15A SIRT1 0 0 460 460 1 2
    PPP1R15A MCL1 0 0 290 346 1 2
    PPP1R15A MAP3K5 0 0 509 534 1 1
    PPP1R15A IP6K2 0 0 123 273 1 1
    PPP1R15A SMAD7 270 900 985 998 1 1
    PPP1R15A BACE1 0 0 180 179 1 1
    PPP1R15A PPA1 0 0 176 176 1 1
    PPP1R15A LYN 270 0 665 780 1 1
    PPP1R15A IFNB1 0 0 261 261 1 1
    PPP1R15A PPP1CA 639 900 986 999 1 1
    PPP1R15A MAPK6 0 0 91 184 1 1
    PPP1R15A ESR1 0 0 180 179 1 1
    PPP1R15A ATG5 0 0 284 292 1 2
    PPP1R15A PPP2R2C 0 540 0 559 1 1
    PPP1R15A PPP5D1 0 0 0 226 1 1
    PPP1R15A TIA1 0 0 254 271 1 1
    PPP1R15A SH2D3A 0 0 218 218 1 1
    PPP1R15A PRKD1 0 0 293 293 1 1
    PPP1R15A PDIA5 0 0 202 202 1 1
    PPP1R15A XBP1 0 0 801 861 1 2
    PPP1R15A ZFAND2B 0 0 0 450 1 1
    PPP1R15A MANF 0 0 139 192 1 1
    PPP1R15A IRF1 0 0 167 219 1 1
    PPP1R15A ATG10 0 0 137 157 1 2
    PPP1R15A SMEK2 0 360 0 360 1 1
    PPP1R15A TGFBR1 0 900 298 931 1 1
    PPP1R15A RT14 0 0 151 152 1 1
    PPP1R15A HSPB1 0 0 167 185 1 1
    PPP1R15A HSPB2 0 0 157 156 1 1
    PPP1R15A VPS33B 0 0 0 183 1 1
    PPP1R15A ISG15 0 0 142 161 1 1
    PPP1R15A EIF2A 0 0 330 342 1 1
    PPP1R15A MAP1LC3B 0 0 260 304 1 2
    PPP1R15A DUSP14 0 0 150 172 1 1
    PPP1R15A F2RL3 0 0 154 153 1 1
    PPP1R15A PTP4A1 0 0 112 216 1 1
    PPP1R15A ELP6 0 0 55 261 1 1
    PPP1R15A STMN1 0 0 165 165 1 1
    PPP1R15A SEL1L 0 0 141 231 1 1
    PPP1R15A ULK1 0 0 178 177 1 2
    PPP1R15A EIF4G2 0 0 180 180 1 1
    PPP1R15A NBN 0 0 148 171 1 1
    PPP1R15A C20orf27 0 0 181 251 1 1
    PPP1R15A PLK3 0 0 113 204 1 1
    PPP1R15A PCBP1 114 0 73 169 1 1
    PPP1R15A TIAL1 0 0 433 446 1 1
    PPP1R15A MAP4K4 0 0 46 150 1 1
    PPP1R15A UNC5B 0 0 45 259 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0071074 Molecular Function eukaryotic initiation factor eIF2 binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0019901 Molecular Function protein kinase binding enables IPI
    GO:0008157 Molecular Function protein phosphatase 1 binding enables IDA
    GO:0008157 Molecular Function protein phosphatase 1 binding enables IPI
    GO:0072542 Molecular Function protein phosphatase activator activity enables IDA
    GO:0019888 Molecular Function protein phosphatase regulator activity enables IBA
    GO:0019888 Molecular Function protein phosphatase regulator activity enables IDA
    GO:0019888 Molecular Function protein phosphatase regulator activity enables ISS
    GO:0006974 Biological Process DNA damage response involved_in TAS
    GO:0006915 Biological Process apoptotic process involved_in TAS
    GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress involved_in TAS
    GO:1903898 Biological Process negative regulation of PERK-mediated unfolded protein response involved_in TAS
    GO:1901798 Biological Process positive regulation of signal transduction by p53 class mediator involved_in ISS
    GO:0032058 Biological Process positive regulation of translational initiation in response to stress involved_in IDA
    GO:0070972 Biological Process protein localization to endoplasmic reticulum involved_in IMP
    GO:0051726 Biological Process regulation of cell cycle involved_in TAS
    GO:0036490 Biological Process regulation of translation in response to endoplasmic reticulum stress involved_in IDA
    GO:0006446 Biological Process regulation of translational initiation involved_in IDA
    GO:0043558 Biological Process regulation of translational initiation in response to stress involved_in IDA
    GO:0043558 Biological Process regulation of translational initiation in response to stress involved_in ISS
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IBA
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IDA
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005783 Cellular Component endoplasmic reticulum is_active_in IBA
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in NAS
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0005741 Cellular Component mitochondrial outer membrane located_in IEA
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0000164 Cellular Component protein phosphatase type 1 complex part_of IBA
    GO:0000164 Cellular Component protein phosphatase type 1 complex part_of IDA
    GO:0000164 Cellular Component protein phosphatase type 1 complex part_of IPI
    Pathways
    Name DB ID
    Signal Transduction Reactome R-HSA-162582
    Signaling by TGF-beta Receptor Complex Reactome R-HSA-170834
    Downregulation of TGF-beta receptor signaling Reactome R-HSA-2173788
    TGF-beta receptor signaling activates SMADs Reactome R-HSA-2173789
    Cellular responses to stress Reactome R-HSA-2262752
    Cellular responses to stimuli Reactome R-HSA-8953897
    Signaling by TGFB family members Reactome R-HSA-9006936
    Response of EIF2AK1 (HRI) to heme deficiency Reactome R-HSA-9648895
    Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
    Unfolded protein response (WP4925) WikiPathways WP4925_r123438
    Photodynamic therapy-induced unfolded protein response (WP3613) WikiPathways WP3613_r106539
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_014330 5 mRNA None NC_000019 Reference