DAPK2

death associated protein kinase 2
General Information
Name death associated protein kinase 2
Alias
  • death-associated protein kinase 2
  • DAP kinase 2
Synonyms DRP-1 MGC119312 DRP1
Gene_family Death associated protein kinases
organism Homo sapiens
entrez_id 23604
location 15q22.31
transcript_count 24
exon_count 16
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008]
      Stringdb Death-associated protein kinase 2; Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in g [...]
      nextProt Is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    DAPK2 BioGRID RPL10 GeneID BioGRID Cross-Linking-MS (XL-MS)
    DAPK2 BioGRID MYLK2 GeneID BioGRID Negative Genetic
    DAPK2 BioGRID SLK GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID CIT GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID ECT2 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID VDAC2 GeneID BioGRID Proximity Label-MS
    DAPK2 BioGRID CCDC91 GeneID BioGRID Two-hybrid
    DAPK2 BioGRID ATG5 GeneID BioGRID Affinity Capture-Western
    DAPK2 BioGRID TP73 GeneID BioGRID Affinity Capture-Western
    DAPK2 BioGRID Bub1 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID KLC3 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID TUBGCP5 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID RACGAP1 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID LLGL2 GeneID BioGRID Affinity Capture-MS
    DAPK2 BioGRID FAM9B GeneID BioGRID Two-hybrid
    DAPK2 BioGRID DAPK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    DAPK2 BioGRID APP GeneID BioGRID Reconstituted Complex
    DAPK2 Protein DAPK2 GeneID HPRD None
    DAPK2 Protein CAMK2A GeneID HPRD None
    DAPK2 Protein MLC1 GeneID HPRD None
    DAPK2 Protein TGFBR1 GeneID HPRD None
    StringDB
    A B experiments database textmining combined score hadb nhadb
    DAPK2 PTEN 0 0 134 167 1 2
    DAPK2 NEK7 0 0 0 168 1 1
    DAPK2 MAPK7 0 0 0 201 1 1
    DAPK2 PRKAA2 0 0 82 192 1 2
    DAPK2 SRCAP 0 0 0 157 1 1
    DAPK2 PARP16 0 0 134 157 1 1
    DAPK2 MAPK10 0 0 66 166 1 2
    DAPK2 MAPK14 0 0 81 288 1 1
    DAPK2 ATM 0 0 70 222 1 1
    DAPK2 BTBD17 0 0 0 165 1 1
    DAPK2 AIF1L 0 0 0 181 1 1
    DAPK2 EIF3F 0 0 70 213 1 1
    DAPK2 GNAI1 0 0 0 171 1 1
    DAPK2 EPS8 0 0 181 284 1 1
    DAPK2 FAIM2 0 0 89 503 1 1
    DAPK2 ITGB4 0 0 137 154 1 1
    DAPK2 TGFBR1 83 0 0 216 1 1
    DAPK2 CDKL4 0 0 0 169 1 1
    DAPK2 DFFB 0 0 134 284 1 1
    DAPK2 EHBP1 0 0 0 178 1 1
    DAPK2 MYO1F 0 0 0 154 1 1
    DAPK2 PPP1R14A 0 0 122 354 1 1
    DAPK2 STK39 0 0 0 167 1 1
    DAPK2 NEK2 0 0 0 161 1 1
    DAPK2 UNC5B 0 600 217 711 1 1
    DAPK2 AKT3 0 0 62 173 1 1
    DAPK2 SMARCA4 0 0 0 150 1 1
    DAPK2 DDIT4L 0 0 125 323 1 1
    DAPK2 LYN 0 0 44 169 1 1
    DAPK2 RCVRN 0 0 60 178 1 1
    DAPK2 PDIK1L 0 0 0 223 1 1
    DAPK2 HOXB8 0 0 61 160 1 1
    DAPK2 RAB13 0 0 0 242 1 2
    DAPK2 MAPK6 0 0 0 202 1 1
    DAPK2 PPP1CA 0 0 0 193 1 1
    DAPK2 DGKA 0 0 0 188 1 1
    DAPK2 GNA11 0 0 0 157 1 1
    DAPK2 MYL3 0 0 0 179 1 1
    DAPK2 CAMTA2 0 0 248 702 1 1
    DAPK2 ATG5 270 0 95 311 1 2
    DAPK2 MAP2K6 0 0 92 181 1 1
    DAPK2 PPP5D1 0 0 0 182 1 1
    DAPK2 RAD51D 0 0 0 164 1 1
    DAPK2 SASH3 0 0 142 527 1 1
    DAPK2 ARHGAP28 0 0 156 167 1 1
    DAPK2 GNAI3 0 0 103 225 1 2
    DAPK2 ENSG00000267618 0 0 0 164 1 1
    DAPK2 NCALD 0 0 0 161 1 1
    DAPK2 GNAO1 0 0 0 171 1 1
    DAPK2 TM9SF2 0 0 155 377 1 1
    DAPK2 CDKN2B 0 0 155 177 1 1
    DAPK2 PIM3 0 0 66 193 1 1
    DAPK2 WDR83OS 0 0 268 322 1 1
    DAPK2 CDK9 0 0 48 163 1 1
    DAPK2 TSPAN2 0 0 107 245 1 1
    DAPK2 SLC4A11 0 0 96 271 1 1
    DAPK2 MYO3B 0 0 0 153 1 1
    DAPK2 PNKD 0 0 127 179 1 1
    DAPK2 E2F1 0 0 138 156 1 1
    DAPK2 RAD1 0 0 0 177 1 1
    DAPK2 ASB5 0 0 178 200 1 1
    DAPK2 PITRM1 0 0 123 166 1 1
    DAPK2 AIFM3 0 0 124 184 1 1
    DAPK2 PSMD3 0 0 0 222 1 1
    DAPK2 EFCAB9 0 0 0 181 1 1
    DAPK2 ZRANB3 0 0 0 150 1 1
    DAPK2 PRSS33 0 0 212 224 1 1
    DAPK2 CCDC80 0 0 181 608 1 1
    DAPK2 HCK 0 0 0 157 1 1
    DAPK2 STK24 0 0 102 199 1 1
    DAPK2 BLK 0 0 91 173 1 1
    DAPK2 CALM2 800 0 0 829 1 1
    DAPK2 EHBP1L1 0 0 0 178 1 1
    DAPK2 CASP4 0 0 265 278 1 2
    DAPK2 HELLS 0 0 69 174 1 1
    DAPK2 DIRAS3 0 0 204 227 1 2
    DAPK2 MIEN1 0 0 146 340 1 1
    DAPK2 KLHL20 0 0 213 219 1 1
    DAPK2 BCAR1 0 0 52 197 1 1
    DAPK2 RPSA 0 0 213 226 1 1
    DAPK2 CHP2 0 0 0 217 1 1
    DAPK2 KCNIP1 0 0 0 161 1 1
    DAPK2 HSPB8 0 0 164 163 1 2
    DAPK2 GNA15 0 0 0 157 1 1
    DAPK2 EFCAB7 0 0 0 181 1 1
    DAPK2 PACSIN1 0 0 170 169 1 1
    DAPK2 GIMAP2 0 0 0 214 1 1
    DAPK2 VDAC1 0 0 143 182 1 2
    DAPK2 C1QTNF4 0 0 164 163 1 1
    DAPK2 PKMYT1 0 0 0 239 1 1
    DAPK2 TESC 0 0 0 217 1 1
    DAPK2 LYPLA2 0 0 0 208 1 1
    DAPK2 C2orf80 0 0 256 256 1 1
    DAPK2 PPA2 0 0 0 176 1 1
    DAPK2 TP53INP1 0 0 167 347 1 2
    DAPK2 MAP3K19 0 0 161 172 1 1
    DAPK2 INO80 0 0 0 152 1 1
    DAPK2 PPP3CA 0 0 0 201 1 1
    DAPK2 GUCA1A 0 0 0 161 1 1
    DAPK2 EP400NL 0 0 0 157 1 1
    DAPK2 GBAS 0 0 124 155 1 1
    DAPK2 TPM3 0 0 52 206 1 1
    DAPK2 TNFSF8 0 0 299 299 1 1
    DAPK2 CARD6 0 0 195 203 1 1
    DAPK2 PDPR 0 0 135 171 1 1
    DAPK2 NDUFB10 0 0 0 171 1 1
    DAPK2 USP53 0 0 127 449 1 1
    DAPK2 CLHC1 0 0 0 182 1 1
    DAPK2 FILIP1L 0 0 119 153 1 1
    DAPK2 DHODH 0 0 90 152 1 1
    DAPK2 ACVR1B 0 0 54 167 1 1
    DAPK2 KLHDC9 0 0 0 161 1 1
    DAPK2 CDK18 0 0 0 218 1 1
    DAPK2 DGKG 0 0 112 492 1 1
    DAPK2 VMP1 0 0 180 179 1 2
    DAPK2 TMEM74 0 0 401 400 1 2
    DAPK2 TECPR2 0 0 135 153 1 2
    DAPK2 ABHD10 0 0 165 183 1 1
    DAPK2 DKK3 0 0 96 358 1 1
    DAPK2 CABP1 0 0 0 181 1 1
    DAPK2 TNNC2 0 0 0 181 1 1
    DAPK2 GNAI2 0 0 0 171 1 1
    DAPK2 NME6 0 0 143 467 1 1
    DAPK2 MRPL47 0 0 164 163 1 1
    DAPK2 TSSK1B 0 0 0 197 1 1
    DAPK2 MFHAS1 0 0 146 160 1 1
    DAPK2 PPTC7 0 0 181 287 1 1
    DAPK2 MYL4 0 0 0 179 1 1
    DAPK2 THNSL2 0 0 134 229 1 1
    DAPK2 RAB40A 0 0 0 242 1 1
    DAPK2 SNX25 0 0 56 169 1 1
    DAPK2 CDK17 0 0 0 214 1 1
    DAPK2 GADD45A 0 0 166 165 1 1
    DAPK2 MAPK1 0 800 81 852 1 2
    DAPK2 PPP2CA 0 0 0 193 1 1
    DAPK2 SCG3 0 0 148 172 1 1
    DAPK2 HMGCR 0 0 0 171 1 1
    DAPK2 SYN3 0 0 0 171 1 1
    DAPK2 MYL2 0 0 73 196 1 1
    DAPK2 ACTN1 0 0 459 536 1 1
    DAPK2 PRKAA1 0 0 0 187 1 2
    DAPK2 PLAGL2 0 0 86 191 1 1
    DAPK2 DFFA 0 0 67 165 1 1
    DAPK2 GNB2L1 0 0 0 156 1 1
    DAPK2 MAP2K2 0 0 61 251 1 1
    DAPK2 HPCA 0 0 0 161 1 1
    DAPK2 LYZL4 0 0 252 310 1 1
    DAPK2 TSSK2 0 0 0 195 1 1
    DAPK2 CACYBP 0 0 127 365 1 1
    DAPK2 PVALB 0 0 0 181 1 1
    DAPK2 SGK2 0 0 0 202 1 1
    DAPK2 CALML5 0 0 0 181 1 1
    DAPK2 ERO1L 0 0 193 331 1 1
    DAPK2 ANXA8 0 0 82 150 1 1
    DAPK2 CDK5 0 0 123 177 1 2
    DAPK2 C21orf91 0 0 163 193 1 1
    DAPK2 CALML3 0 0 0 181 1 1
    DAPK2 CDK16 0 0 95 224 1 1
    DAPK2 SGK494 0 0 0 158 1 1
    DAPK2 USP32 0 0 0 180 1 1
    DAPK2 KCNIP3 0 0 0 161 1 1
    DAPK2 PPP1CB 0 0 0 193 1 1
    DAPK2 CABP5 0 0 0 181 1 1
    DAPK2 PPP2CB 0 0 0 193 1 1
    DAPK2 CALML4 0 0 0 181 1 1
    DAPK2 TPM2 0 0 71 238 1 1
    DAPK2 ANKRD30A 0 0 150 224 1 1
    DAPK2 CLVS1 0 0 183 200 1 1
    DAPK2 PPP3R2 0 0 0 217 1 1
    DAPK2 ACTN2 0 0 100 269 1 1
    DAPK2 MAP2K4 0 0 48 175 1 1
    DAPK2 CTDSPL 0 0 0 182 1 1
    DAPK2 MAPK8 0 0 66 183 1 2
    DAPK2 MYLPF 0 0 0 168 1 1
    DAPK2 GAK 0 0 0 163 1 1
    DAPK2 SYCE3 0 0 127 365 1 1
    DAPK2 GNAZ 0 0 0 171 1 1
    DAPK2 EPS15L1 0 0 0 154 1 1
    DAPK2 CYCS 0 0 189 195 1 1
    DAPK2 CAMKK1 0 0 0 152 1 1
    DAPK2 AIFM2 0 0 113 174 1 1
    DAPK2 NKAPL 0 0 0 151 1 1
    DAPK2 CLTC 0 0 0 182 1 1
    DAPK2 VWA9 0 0 232 231 1 1
    DAPK2 SMARCA2 0 0 0 150 1 1
    DAPK2 DAPK1 0 800 778 804 1 2
    DAPK2 CTDSP2 0 0 0 182 1 1
    DAPK2 DIS3L 0 0 139 179 1 1
    DAPK2 CDKL1 0 0 0 169 1 1
    DAPK2 KIAA0226L 0 0 142 218 1 1
    DAPK2 WDR31 0 0 0 181 1 1
    DAPK2 MYH7B 0 0 0 164 1 1
    DAPK2 RABEPK 0 0 0 161 1 1
    DAPK2 HPCAL1 0 0 0 161 1 1
    DAPK2 AIF1 0 0 0 181 1 1
    DAPK2 ZNF781 0 0 218 255 1 1
    DAPK2 GORASP2 0 0 90 389 1 1
    DAPK2 MSMB 0 0 134 603 1 1
    DAPK2 MYO3A 0 0 0 151 1 1
    DAPK2 CIB4 0 0 0 217 1 1
    DAPK2 ENSG00000270024 0 0 0 256 1 1
    DAPK2 PRKACB 0 0 0 231 1 1
    DAPK2 MFN1 0 0 170 188 1 1
    DAPK2 MOB2 0 0 136 176 1 1
    DAPK2 ARAP3 0 0 112 169 1 1
    DAPK2 CETN2 0 0 0 179 1 1
    DAPK2 CDC25C 0 0 0 179 1 1
    DAPK2 RMND1 0 0 144 177 1 1
    DAPK2 EYS 0 0 0 160 1 1
    DAPK2 FYN 0 0 46 154 1 1
    DAPK2 DMC1 0 0 0 223 1 1
    DAPK2 RASL12 0 0 193 225 1 1
    DAPK2 PARVB 0 0 0 303 1 1
    DAPK2 AURKA 0 0 122 183 1 2
    DAPK2 SYN1 0 0 0 171 1 1
    DAPK2 MYL1 0 0 0 179 1 1
    DAPK2 GNA12 0 0 0 171 1 1
    DAPK2 KLHDC10 0 0 0 161 1 1
    DAPK2 ECT2 270 0 0 275 1 1
    DAPK2 MYL12B 0 0 0 168 1 1
    DAPK2 PSD4 0 0 150 214 1 1
    DAPK2 MAPK3 0 800 120 857 1 2
    DAPK2 BNIP3 0 0 405 413 1 2
    DAPK2 SQSTM1 0 0 135 176 1 2
    DAPK2 CENPT 0 0 90 183 1 1
    DAPK2 GNA14 0 0 0 157 1 1
    DAPK2 TP73 270 0 233 421 1 2
    DAPK2 HSP90AA1 0 0 74 157 1 2
    DAPK2 KLHDC1 0 0 0 161 1 1
    DAPK2 HOXA4 0 0 63 206 1 1
    DAPK2 KLC3 226 0 0 231 1 1
    DAPK2 PASK 0 0 0 168 1 1
    DAPK2 EFCAB3 0 0 0 181 1 1
    DAPK2 MFN2 0 0 261 277 1 2
    DAPK2 GIMAP5 0 0 0 214 1 1
    DAPK2 TCTE1 0 0 72 183 1 1
    DAPK2 PDCD5 0 0 150 208 1 1
    DAPK2 RAD51 0 0 0 164 1 1
    DAPK2 TRIB2 0 0 0 170 1 1
    DAPK2 C1RL 0 0 134 342 1 1
    DAPK2 MTOR 0 0 129 211 1 2
    DAPK2 GUCA1C 0 0 0 161 1 1
    DAPK2 MYL6B 0 0 0 179 1 1
    DAPK2 ALDH3B1 0 0 95 195 1 1
    DAPK2 GZMB 0 0 163 224 1 1
    DAPK2 RAD51C 0 0 0 223 1 1
    DAPK2 GNA13 0 0 0 171 1 1
    DAPK2 CHD1L 0 0 0 150 1 1
    DAPK2 CHP1 0 0 0 217 1 1
    DAPK2 PIK3C3 0 0 122 212 1 2
    DAPK2 PPP4C 0 0 0 160 1 1
    DAPK2 ZNF628 0 0 391 724 1 1
    DAPK2 CLTCL1 0 0 0 182 1 1
    DAPK2 CA3 0 0 60 224 1 1
    DAPK2 NCS1 0 0 0 161 1 1
    DAPK2 RAB40B 0 0 0 242 1 1
    DAPK2 RAB40AL 0 0 0 242 1 1
    DAPK2 KLF6 0 0 175 214 1 1
    DAPK2 RDH12 0 0 81 199 1 1
    DAPK2 CCNJ 0 0 155 154 1 1
    DAPK2 TSSK3 0 0 0 174 1 1
    DAPK2 TSEN15 0 0 155 341 1 1
    DAPK2 GAPDH 0 0 180 197 1 2
    DAPK2 DUSP5 0 0 113 168 1 1
    DAPK2 BNIPL 0 0 142 167 1 1
    DAPK2 HLTF 0 0 0 150 1 1
    DAPK2 HORMAD1 0 0 0 278 1 1
    DAPK2 CKS2 0 0 125 156 1 1
    DAPK2 PARK2 0 0 0 192 1 1
    DAPK2 PPP5C 0 0 0 164 1 1
    DAPK2 CETN3 0 0 0 179 1 1
    DAPK2 MYO15A 0 0 0 167 1 1
    DAPK2 HIGD1B 0 0 241 240 1 1
    DAPK2 GNAQ 0 0 0 157 1 1
    DAPK2 CELA1 0 0 156 243 1 1
    DAPK2 PIM1 0 0 72 187 1 1
    DAPK2 HELT 0 0 123 206 1 1
    DAPK2 ZNF343 0 0 0 163 1 1
    DAPK2 CHN2 0 0 99 155 1 1
    DAPK2 MAP3K8 0 0 0 182 1 1
    DAPK2 ZKSCAN1 0 0 108 150 1 1
    DAPK2 STK11 0 0 135 197 1 2
    DAPK2 KIF20B 0 0 95 171 1 1
    DAPK2 MYL9 0 0 123 239 1 1
    DAPK2 PPP1CC 0 0 0 193 1 1
    DAPK2 MYL10 0 0 0 168 1 1
    DAPK2 CFLAR 0 0 129 171 1 1
    DAPK2 PALM 0 0 0 153 1 1
    DAPK2 EPS15 0 0 0 154 1 1
    DAPK2 EFCAB6 0 0 0 181 1 1
    DAPK2 BTBD6 0 0 0 165 1 1
    DAPK2 TGM2 0 0 74 166 1 1
    DAPK2 TP53 0 0 293 307 1 2
    DAPK2 RASEF 0 0 0 261 1 1
    DAPK2 RAB10 0 0 0 242 1 1
    DAPK2 DNAH8 0 0 113 168 1 1
    DAPK2 MYL6 0 0 0 179 1 1
    DAPK2 OCM 0 0 0 181 1 1
    DAPK2 DUOXA2 0 0 92 216 1 1
    DAPK2 USP54 0 0 0 188 1 1
    DAPK2 CALM3 800 0 0 829 1 1
    DAPK2 TNNC1 0 0 0 181 1 1
    DAPK2 FRY 0 0 240 250 1 1
    DAPK2 GNAT1 0 0 0 171 1 1
    DAPK2 RHBDL3 0 0 0 243 1 1
    DAPK2 RAB8A 0 0 0 242 1 2
    DAPK2 PMVK 0 0 72 213 1 1
    DAPK2 CABP7 0 0 0 181 1 1
    DAPK2 ENSG00000273398 0 0 0 217 1 1
    DAPK2 NKAP 0 0 0 151 1 1
    DAPK2 DACT3 0 0 130 153 1 1
    DAPK2 BAG1 0 0 94 260 1 2
    DAPK2 TSSK6 0 0 0 201 1 1
    DAPK2 TRIM32 0 0 53 193 1 1
    DAPK2 STRADB 0 0 45 160 1 1
    DAPK2 IRAK4 0 0 45 222 1 1
    DAPK2 ASPM 0 0 0 263 1 1
    DAPK2 PPP3R1 0 0 0 217 1 1
    DAPK2 PACSIN3 0 0 118 154 1 1
    DAPK2 HMOX2 0 0 0 188 1 1
    DAPK2 PSMC3IP 0 0 0 262 1 1
    DAPK2 MAP1LC3B 0 0 135 158 1 2
    DAPK2 BTBD1 0 0 0 165 1 1
    DAPK2 CDC25B 0 0 0 179 1 1
    DAPK2 CAMK2A 213 0 0 270 1 2
    DAPK2 CLK2 0 0 244 150 1 1
    DAPK2 RASL11B 0 0 134 219 1 1
    DAPK2 RAD51B 0 0 0 164 1 1
    DAPK2 PPA1 0 0 0 176 1 1
    DAPK2 PIM2 0 0 0 201 1 2
    DAPK2 CABP2 0 0 0 181 1 1
    DAPK2 RAB15 0 0 0 242 1 1
    DAPK2 MYH11 0 0 0 171 1 1
    DAPK2 CTDNEP1 0 0 0 182 1 1
    DAPK2 CDC25A 0 0 0 179 1 1
    DAPK2 SYNRG 0 0 0 154 1 1
    DAPK2 MAPK11 0 0 0 288 1 1
    DAPK2 ANXA1 0 0 120 163 1 1
    DAPK2 BECN1 0 800 202 840 1 2
    DAPK2 EEF1G 0 0 0 158 1 1
    DAPK2 MYO16 0 0 0 164 1 1
    DAPK2 PLA2G2F 0 0 144 168 1 1
    DAPK2 DCPS 0 0 0 157 1 1
    DAPK2 TSSK4 0 0 0 193 1 1
    DAPK2 HOXC8 0 0 57 202 1 1
    DAPK2 SLC35B1 0 0 147 397 1 1
    DAPK2 DEPTOR 0 0 451 451 1 1
    DAPK2 ERO1LB 0 0 67 227 1 1
    DAPK2 GSK3B 0 0 48 203 1 2
    DAPK2 CDKN2A 0 0 166 188 1 2
    DAPK2 PPP6C 0 0 0 189 1 1
    DAPK2 SMARCA1 0 0 0 150 1 1
    DAPK2 MAPK15 0 0 51 265 1 2
    DAPK2 TNFRSF10B 0 0 167 167 1 1
    DAPK2 TMEM65 0 0 201 238 1 1
    DAPK2 CTSS 0 0 82 158 1 1
    DAPK2 CASP3 0 650 268 732 1 2
    DAPK2 SAMD4A 0 0 195 546 1 1
    DAPK2 CTSZ 0 0 81 342 1 1
    DAPK2 CYP26B1 0 0 63 191 1 1
    DAPK2 HMOX1 0 0 45 192 1 2
    DAPK2 DGKB 0 0 0 267 1 1
    DAPK2 MOS 0 0 0 216 1 1
    DAPK2 ERAL1 0 0 456 456 1 1
    DAPK2 NTN1 0 0 66 164 1 1
    DAPK2 BNIP3L 0 0 96 187 1 2
    DAPK2 OXSM 0 0 193 227 1 1
    DAPK2 TRRAP 0 0 0 158 1 1
    DAPK2 RAB28 0 0 0 242 1 1
    DAPK2 TSC2 0 0 134 160 1 2
    DAPK2 GORASP1 0 0 0 217 1 1
    DAPK2 STK3 0 0 134 185 1 1
    DAPK2 YWHAB 0 0 678 710 1 1
    DAPK2 SRC 0 0 97 188 1 1
    DAPK2 MCM3 0 0 74 153 1 1
    DAPK2 CIB1 0 0 0 217 1 1
    DAPK2 WBSCR22 0 0 117 317 1 1
    DAPK2 EFCAB11 0 0 0 181 1 1
    DAPK2 STK25 0 0 0 163 1 1
    DAPK2 TEN1-CDK3 0 0 0 215 1 1
    DAPK2 TRIML2 0 0 181 221 1 1
    DAPK2 IL24 0 0 45 153 1 2
    DAPK2 CETN1 0 0 0 179 1 1
    DAPK2 BTBD2 0 0 0 165 1 1
    DAPK2 SCGN 0 0 0 181 1 1
    DAPK2 EFCAB13 0 0 0 181 1 1
    DAPK2 CDK15 0 0 0 226 1 1
    DAPK2 GUCA1B 0 0 0 161 1 1
    DAPK2 LARP4B 0 0 124 165 1 1
    DAPK2 MAGEF1 0 0 193 201 1 1
    DAPK2 AKT1 0 0 218 221 1 2
    DAPK2 UBLCP1 0 0 0 187 1 1
    DAPK2 TMEM143 0 0 257 257 1 1
    DAPK2 SGK3 0 0 0 271 1 1
    DAPK2 CARD14 0 0 156 292 1 1
    DAPK2 GNAL 0 0 0 164 1 1
    DAPK2 USO1 0 0 0 171 1 1
    DAPK2 MRPL33 0 0 171 177 1 1
    DAPK2 ATF4 270 0 0 366 1 2
    DAPK2 RAB40C 0 0 0 242 1 1
    DAPK2 STAG3 0 0 82 184 1 1
    DAPK2 PPP2R4 0 0 75 196 1 1
    DAPK2 STK32C 0 0 0 197 1 1
    DAPK2 SYN2 0 0 0 171 1 1
    DAPK2 CDK3 0 0 0 215 1 1
    DAPK2 CCND2 0 0 76 170 1 1
    DAPK2 CALN1 0 0 0 181 1 1
    DAPK2 RND3 0 0 57 177 1 1
    DAPK2 NCAPH2 0 0 0 167 1 1
    DAPK2 RPS6KB1 0 0 92 203 1 2
    DAPK2 HOXC6 0 0 60 274 1 1
    DAPK2 CDK1 0 0 90 208 1 1
    DAPK2 SGK1 0 0 81 210 1 1
    DAPK2 ABCG2 0 0 111 163 1 1
    DAPK2 ATR 0 0 0 223 1 1
    DAPK2 RAB44 0 0 0 242 1 1
    DAPK2 ULK3 0 0 96 175 1 2
    DAPK2 PPM1M 0 0 69 172 1 1
    DAPK2 GRID1 0 0 293 319 1 2
    DAPK2 MLC1 213 0 0 218 1 1
    DAPK2 ANKRD10 0 0 69 150 1 1
    DAPK2 RAD54B 0 0 0 264 1 1
    DAPK2 AVEN 0 0 210 221 1 1
    DAPK2 VPS41 0 0 0 170 1 1
    DAPK2 TMEM160 0 0 150 181 1 1
    DAPK2 DEK 0 0 57 158 1 1
    DAPK2 HPGD 0 0 103 189 1 1
    DAPK2 CAT 0 0 0 164 1 1
    DAPK2 GSTT2B 0 0 89 172 1 1
    DAPK2 NEK6 0 0 0 174 1 1
    DAPK2 CASP8 0 0 167 167 1 2
    DAPK2 MCM4 0 0 0 165 1 1
    DAPK2 NOTCH3 0 0 66 150 1 1
    DAPK2 EFCAB1 0 0 0 161 1 1
    DAPK2 CABP4 0 0 0 206 1 1
    DAPK2 TPM4 0 0 0 197 1 1
    DAPK2 FRK 0 0 0 203 1 1
    DAPK2 TRIM21 0 0 45 153 1 1
    DAPK2 CDK6 0 0 128 233 1 1
    DAPK2 OCM2 0 0 0 181 1 1
    DAPK2 MAP1LC3C 0 0 211 232 1 2
    DAPK2 CALML6 0 0 0 181 1 1
    DAPK2 STK32A 0 0 0 211 1 1
    DAPK2 DAPK3 0 800 681 807 1 2
    DAPK2 GRINA 0 0 0 225 1 1
    DAPK2 RPS6KB2 0 0 0 200 1 2
    DAPK2 CYP3A5 0 0 0 187 1 1
    DAPK2 SPATA21 0 0 0 181 1 1
    DAPK2 SCIN 0 0 160 257 1 1
    DAPK2 AURKB 0 0 66 178 1 1
    DAPK2 HORMAD2 0 0 0 278 1 1
    DAPK2 CAMTA1 0 0 0 423 1 1
    DAPK2 FASN 0 0 217 260 1 1
    DAPK2 ARL11 0 0 157 200 1 1
    DAPK2 SMARCA5 0 0 0 150 1 1
    DAPK2 RAB8B 0 0 0 242 1 2
    DAPK2 MYL12A 0 0 60 184 1 1
    DAPK2 CHEK2 0 0 74 174 1 1
    DAPK2 THSD1 0 0 154 155 1 1
    DAPK2 MAPK9 0 0 45 174 1 2
    DAPK2 ITPR1 0 0 167 192 1 2
    DAPK2 CASP9 0 0 196 196 1 1
    DAPK2 NMRK2 0 0 157 158 1 1
    DAPK2 GNAS 0 0 0 176 1 1
    DAPK2 HPCAL4 0 0 0 161 1 1
    DAPK2 RPTOR 0 0 134 229 1 2
    DAPK2 STK16 0 0 0 153 1 1
    DAPK2 TRIP13 0 0 0 161 1 1
    DAPK2 MYL7 0 0 0 168 1 1
    DAPK2 C1orf105 0 0 153 205 1 1
    DAPK2 ITPR3 0 0 155 181 1 1
    DAPK2 AURKC 0 0 0 160 1 1
    DAPK2 EFR3A 0 0 262 395 1 1
    DAPK2 CALB1 0 0 0 181 1 1
    DAPK2 MAPK12 0 0 46 295 1 1
    DAPK2 BCL2L11 0 0 167 167 1 1
    DAPK2 MAP2K3 0 0 0 179 1 1
    DAPK2 MST4 0 0 0 174 1 1
    DAPK2 TNFSF10 0 0 211 229 1 2
    DAPK2 CHEK1 0 0 0 151 1 1
    DAPK2 NINJ2 0 0 120 184 1 1
    DAPK2 NEK3 0 0 0 152 1 1
    DAPK2 VSNL1 0 0 0 161 1 1
    DAPK2 CYB5B 0 0 122 160 1 1
    DAPK2 CDKL2 0 0 134 200 1 1
    DAPK2 LOXL4 0 0 74 235 1 1
    DAPK2 NIM1K 0 0 0 206 1 1
    DAPK2 STK4 0 0 71 184 1 1
    DAPK2 GTF2H1 0 0 75 379 1 1
    DAPK2 BTBD3 0 0 0 165 1 1
    DAPK2 TPM1 0 0 49 204 1 1
    DAPK2 LLGL2 198 0 0 206 1 1
    DAPK2 SPO11 0 0 0 162 1 1
    DAPK2 CIT 270 0 0 309 1 1
    DAPK2 ACTN3 0 0 0 194 1 1
    DAPK2 MAPK13 0 0 0 291 1 1
    DAPK2 RAD54L 0 0 0 264 1 1
    DAPK2 KCNIP2 0 0 0 161 1 1
    DAPK2 PDCD7 0 0 181 245 1 1
    DAPK2 CDK2 0 0 123 247 1 1
    DAPK2 GIMAP8 0 0 150 425 1 1
    DAPK2 PLSCR3 0 0 125 151 1 1
    DAPK2 CALM1 800 0 0 829 1 1
    DAPK2 MYL5 0 0 0 168 1 1
    DAPK2 LYPLA1 0 0 81 428 1 1
    DAPK2 ACTN4 0 0 0 178 1 1
    DAPK2 RAB12 0 0 96 289 1 2
    DAPK2 CRACR2A 0 0 0 242 1 1
    DAPK2 CTDSPL2 0 0 0 182 1 1
    DAPK2 RAD50 0 0 0 151 1 1
    DAPK2 EP400 0 0 0 157 1 1
    DAPK2 CALB2 0 0 0 181 1 1
    DAPK2 PRKACA 0 0 73 239 1 1
    DAPK2 MAPK4 0 0 0 200 1 1
    DAPK2 STARD7 0 0 131 154 1 1
    DAPK2 ANXA5 0 0 236 273 1 1
    DAPK2 KCNIP4 0 0 0 161 1 1
    DAPK2 BCL2L1 0 0 212 212 1 2
    DAPK2 FBXO42 0 0 0 161 1 1
    DAPK2 SMARCAL1 0 0 0 150 1 1
    DAPK2 ATIC 0 0 156 155 1 2
    DAPK2 CCDC91 299 0 0 299 1 1
    DAPK2 CDK10 0 0 0 179 1 1
    DAPK2 AKR7A3 0 0 140 182 1 1
    DAPK2 CIB3 0 0 0 161 1 1
    DAPK2 STK32B 0 0 0 195 1 1
    DAPK2 GNAT2 0 0 0 171 1 1
    DAPK2 PARVA 0 0 82 438 1 1
    DAPK2 CLDN23 0 0 113 168 1 1
    DAPK2 CTDSP1 0 0 0 182 1 1
    DAPK2 PPP3CB 0 0 50 209 1 1
    DAPK2 GNAT3 0 0 0 171 1 1
    DAPK2 CIB2 0 0 0 161 1 1
    DAPK2 SAMD4B 0 0 0 345 1 1
    DAPK2 CIDEB 0 0 108 162 1 1
    DAPK2 PPP3CC 0 0 86 239 1 1
    DAPK2 MAP2K1 0 0 113 268 1 1
    DAPK2 CARD10 0 0 167 270 1 1
    DAPK2 ENSG00000272772 0 0 0 260 1 1
    DAPK2 AKT2 0 0 0 167 1 1
    DAPK2 MAP2K5 0 0 0 264 1 1
    DAPK2 LARP1 0 0 174 213 1 1
    DAPK2 CDK4 0 0 49 224 1 1
    DAPK2 FADD 0 0 134 182 1 2
    DAPK2 TTBK2 0 0 112 178 1 1
    DAPK2 BNIP2 0 0 97 302 1 1
    DAPK2 GART 0 0 0 211 1 1
    DAPK2 PRKX 0 0 0 211 1 1
    DAPK2 PRKACG 0 0 0 241 1 1
    DAPK2 KLHDC2 0 0 0 161 1 1
    DAPK2 HSPBP1 0 0 67 250 1 1
    DAPK2 NME3 0 0 124 156 1 1
    DAPK2 OXSR1 0 0 0 152 1 1
    DAPK2 CAMKK2 0 0 218 194 1 2
    DAPK2 STAT3 0 0 139 163 1 2
    DAPK2 DEAF1 0 0 107 309 1 1
    DAPK2 CDK14 0 0 0 187 1 1
    DAPK2 ZNF337 0 0 91 225 1 1
    DAPK2 SIVA1 0 0 181 194 1 1
    DAPK2 EFCAB2 0 0 0 181 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0004676 Molecular Function 3-phosphoinositide-dependent protein kinase activity enables IEA
    GO:0004679 Molecular Function AMP-activated protein kinase activity enables IEA
    GO:0005524 Molecular Function ATP binding enables IDA
    GO:0004677 Molecular Function DNA-dependent protein kinase activity enables IEA
    GO:0072518 Molecular Function Rho-dependent protein serine/threonine kinase activity enables IEA
    GO:0005516 Molecular Function calmodulin binding enables IDA
    GO:0004694 Molecular Function eukaryotic translation initiation factor 2alpha kinase activity enables IEA
    GO:0044024 Molecular Function histone H2AS1 kinase activity enables IEA
    GO:0072371 Molecular Function histone H2AS121 kinase activity enables IEA
    GO:1990244 Molecular Function histone H2AT120 kinase activity enables IEA
    GO:0035979 Molecular Function histone H2AXS139 kinase activity enables IEA
    GO:0044025 Molecular Function histone H2BS14 kinase activity enables IEA
    GO:0140823 Molecular Function histone H2BS36 kinase activity enables IEA
    GO:0035175 Molecular Function histone H3S10 kinase activity enables IEA
    GO:0044022 Molecular Function histone H3S28 kinase activity enables IEA
    GO:0140855 Molecular Function histone H3S57 kinase activity enables IEA
    GO:0035402 Molecular Function histone H3T11 kinase activity enables IEA
    GO:0072354 Molecular Function histone H3T3 kinase activity enables IEA
    GO:0140857 Molecular Function histone H3T45 kinase activity enables IEA
    GO:0035403 Molecular Function histone H3T6 kinase activity enables IEA
    GO:0044023 Molecular Function histone H4S1 kinase activity enables IEA
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0106310 Molecular Function protein serine kinase activity enables IEA
    GO:0004674 Molecular Function protein serine/threonine kinase activity enables IBA
    GO:0004674 Molecular Function protein serine/threonine kinase activity enables TAS
    GO:0004711 Molecular Function ribosomal protein S6 kinase activity enables IEA
    GO:0043276 Biological Process anoikis involved_in IMP
    GO:0006915 Biological Process apoptotic process involved_in TAS
    GO:0006338 Biological Process chromatin remodeling involved_in IEA
    GO:0035556 Biological Process intracellular signal transduction involved_in IBA
    GO:0035556 Biological Process intracellular signal transduction involved_in IDA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IBA
    GO:2000424 Biological Process positive regulation of eosinophil chemotaxis involved_in IMP
    GO:0090023 Biological Process positive regulation of neutrophil chemotaxis involved_in IMP
    GO:0046777 Biological Process protein autophosphorylation involved_in TAS
    GO:0006468 Biological Process protein phosphorylation involved_in IDA
    GO:0042981 Biological Process regulation of apoptotic process involved_in TAS
    GO:0010506 Biological Process regulation of autophagy involved_in TAS
    GO:2001242 Biological Process regulation of intrinsic apoptotic signaling pathway involved_in IMP
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0034423 Cellular Component autophagosome lumen located_in IEA
    GO:0005737 Cellular Component cytoplasm is_active_in IBA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0031410 Cellular Component cytoplasmic vesicle located_in IEA
    GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
    GO:0005634 Cellular Component nucleus is_active_in IBA
    Pathways
    Name DB ID
    Apoptosis Reactome R-HSA-109581
    Caspase activation via Dependence Receptors in the absence of ligand Reactome R-HSA-418889
    Caspase activation via extrinsic apoptotic signalling pathway Reactome R-HSA-5357769
    Programmed Cell Death Reactome R-HSA-5357801
    Bladder cancer (WP2828) WikiPathways WP2828_r119245
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_169523 1 miscRNA transcript variant 8 NC_000015 Reference
    NR_169524 1 miscRNA transcript variant 9 NC_000015 Reference
    NR_169522 1 miscRNA transcript variant 7 NC_000015 Reference
    NR_172521 1 miscRNA transcript variant 24 NC_000015 Reference
    NM_001385000 1 mRNA transcript variant 6 NC_000015 Reference
    NM_001395283 1 mRNA transcript variant 13 NC_000015 Reference
    NM_001395292 1 mRNA transcript variant 23 NC_000015 Reference
    NM_001395286 1 mRNA transcript variant 17 NC_000015 Reference
    NM_001395284 1 mRNA transcript variant 14 NC_000015 Reference
    NM_001395281 1 mRNA transcript variant 11 NC_000015 Reference
    NM_001395287 1 mRNA transcript variant 18 NC_000015 Reference
    NM_001384999 1 mRNA transcript variant 5 NC_000015 Reference
    NM_001384998 1 mRNA transcript variant 4 NC_000015 Reference
    NM_001395282 1 mRNA transcript variant 12 NC_000015 Reference
    NM_014326 5 mRNA transcript variant 1 NC_000015 Reference
    NM_001384997 1 mRNA transcript variant 3 NC_000015 Reference
    NM_001395293 1 mRNA transcript variant 22 NC_000015 Reference
    NM_001395291 1 mRNA transcript variant 21 NC_000015 Reference
    NM_001395288 1 mRNA transcript variant 19 NC_000015 Reference
    NM_001395279 1 mRNA transcript variant 10 NC_000015 Reference
    NM_001395285 1 mRNA transcript variant 16 NC_000015 Reference
    NM_001395289 1 mRNA transcript variant 15 NC_000015 Reference
    NM_001395290 1 mRNA transcript variant 20 NC_000015 Reference
    NM_001363730 2 mRNA transcript variant 2 NC_000015 Reference