USP33

ubiquitin specific peptidase 33
General Information
Name ubiquitin specific peptidase 33
Alias
  • ubiquitin carboxyl-terminal hydrolase 33
  • VHL-interacting deubiquitinating enzyme 1
  • deubiquitinating enzyme 33
  • pVHL-interacting deubiquitinating enzyme 1
  • ubiquitin thioesterase 33
  • ubiquitin thiolesterase 33
  • ubiquitin-specific-processing protease 33
Synonyms KIAA1097 VDU1
Gene_family Ubiquitin specific peptidases
organism Homo sapiens
entrez_id 23032
location 1p31.1
transcript_count 16
exon_count 27
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
      Stringdb Ubiquitin carboxyl-terminal hydrolase 33; Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the ne [...]
      nextProt Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    USP33 BioGRID CEACAM6 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID ORF3a GeneID BioGRID Proximity Label-MS
    USP33 BioGRID M GeneID BioGRID Proximity Label-MS
    USP33 BioGRID E GeneID BioGRID Proximity Label-MS
    USP33 BioGRID S GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID KRT72 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID FMR1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID SYMPK GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID UBE2A GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TGFBR2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; PCA
    USP33 BioGRID TGFBR1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID SMAD3 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID JAK2 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID PFKFB3 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID CTNNB1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID RNF149 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID DSCR9 GeneID BioGRID Two-hybrid
    USP33 BioGRID ORF1ab GeneID BioGRID Protein-peptide
    USP33 BioGRID Rab18 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID EGFR GeneID BioGRID Affinity Capture-Western; Two-hybrid
    USP33 BioGRID DRD3 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID ARR3 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    USP33 BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID EPAS1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID ADRB2 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID ATG9A GeneID BioGRID Proximity Label-MS
    USP33 BioGRID SNX27 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID RAB7A GeneID BioGRID Proximity Label-MS
    USP33 BioGRID RHOC GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID MYC GeneID BioGRID Affinity Capture-Western; Synthetic Lethality
    USP33 BioGRID KCNA2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID GRIN2A GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID GPR17 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID GABRG2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID APBA2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID LRRTM1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID KRT27 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID VSX2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID MCOLN2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID LPCAT4 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID ZNRF4 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TPTE2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID SPSB4 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID ZDHHC12 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID PCGF6 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TKTL2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TMX1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TMEM134 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID STN1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID C3orf52 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID RXFP1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID CRAMP1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID CT55 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID SPA17 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID ASIC5 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID CTAG2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID IL17RA GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID CGRRF1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID SPINT2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID LRRN2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID EDEM1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID IL32 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID VAPA GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID VAPB GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TRPC3 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TLR2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID TGFA GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID AURKA GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID SKP2 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID GCGR GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID GJD3 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID HSD3B7 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID DERL1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID ELOVL5 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID LRRC59 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID HSD17B11 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID TMT1A GeneID BioGRID Proximity Label-MS
    USP33 BioGRID CKAP4 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID SEC61B GeneID BioGRID Proximity Label-MS
    USP33 BioGRID BCAP31 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID NUP155 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID EBAG9 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID AKAP1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID TMPO GeneID BioGRID Proximity Label-MS
    USP33 BioGRID SEC62 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID STX4 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID STIM1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID SSR1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID RPN2 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID RPN1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID RAB5A GeneID BioGRID Proximity Label-MS
    USP33 BioGRID PXMP2 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID LMNA GeneID BioGRID Proximity Label-MS
    USP33 BioGRID EMD GeneID BioGRID Proximity Label-MS
    USP33 BioGRID ATP2A1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID DNAJC1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID PRKN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    USP33 BioGRID Rnf183 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID DUSP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    USP33 BioGRID CHRM5 GeneID BioGRID Two-hybrid
    USP33 BioGRID SLC25A46 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID OCIAD1 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID SAMM50 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID ST7 GeneID BioGRID Proximity Label-MS
    USP33 BioGRID HERC2 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID OTULINL GeneID BioGRID Proximity Label-MS
    USP33 BioGRID ROBO1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID NRAS GeneID BioGRID Proximity Label-MS
    USP33 BioGRID KRAS GeneID BioGRID Proximity Label-MS
    USP33 BioGRID E7 GeneID BioGRID Affinity Capture-Western; PCA
    USP33 BioGRID E7 GeneID BioGRID PCA
    USP33 BioGRID BTRC GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID UBC GeneID BioGRID Biochemical Activity; Reconstituted Complex
    USP33 BioGRID ARRB2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
    USP33 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID GNAI3 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID MPPED1 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID LDLRAD4 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID VHL GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
    USP33 BioGRID BECN1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID RALB GeneID BioGRID Affinity Capture-Western; Two-hybrid
    USP33 BioGRID RALA GeneID BioGRID Affinity Capture-Western; Two-hybrid
    USP33 BioGRID EXOC2 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID DIO2 GeneID BioGRID Affinity Capture-Western; FRET; Reconstituted Complex; Two-hybrid
    USP33 BioGRID NEURL4 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID USP20 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID CCP110 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    USP33 BioGRID ELOB GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID ELOC GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    USP33 BioGRID TRIM63 GeneID BioGRID Biochemical Activity
    USP33 BioGRID USP28 GeneID BioGRID Biochemical Activity
    USP33 BioGRID TRIM54 GeneID BioGRID Biochemical Activity
    USP33 BioGRID USP21 GeneID BioGRID Biochemical Activity
    USP33 BioGRID USP15 GeneID BioGRID Biochemical Activity
    USP33 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
    USP33 BioGRID ARRB1 GeneID BioGRID Affinity Capture-Western
    USP33 BioGRID PRPF38B GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID ZFR GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID IFIT5 GeneID BioGRID Affinity Capture-MS
    USP33 BioGRID KRR1 GeneID BioGRID Affinity Capture-MS
    USP33 Protein DDX56 GeneID HPRD None
    USP33 Protein DIO2 GeneID HPRD None
    USP33 Protein EIF6 GeneID HPRD None
    USP33 Protein ELOC GeneID HPRD None
    USP33 Protein VHL GeneID HPRD None
    USP33 BioGRID SELENBP1 GeneID BioGRID Reconstituted Complex; Two-hybrid
    USP33 BioGRID DDX56 GeneID BioGRID Two-hybrid
    USP33 BioGRID EIF6 GeneID BioGRID Two-hybrid
    USP33 Protein VHL GeneID BIND pVHL interacts with VDU1-type II.
    StringDB
    A B experiments database textmining combined score hadb nhadb
    USP33 TDRD9 0 0 0 178 1 1
    USP33 FBXO3 0 0 95 155 1 1
    USP33 DUSP15 0 0 46 165 1 1
    USP33 EP400 0 0 88 217 1 1
    USP33 PSMB1 0 0 0 263 1 1
    USP33 BAP1 0 0 163 307 1 1
    USP33 RPS3 0 0 0 167 1 1
    USP33 AP3B1 0 0 125 218 1 1
    USP33 RGS4 0 0 73 172 1 1
    USP33 PLK1 0 0 81 173 1 1
    USP33 SIAH1 0 0 108 185 1 1
    USP33 UBE2B 0 0 73 209 1 1
    USP33 USP43 0 0 455 336 1 1
    USP33 USP17L28 0 0 324 188 1 1
    USP33 RBM23 0 0 0 535 1 1
    USP33 ZRANB1 0 0 427 470 1 1
    USP33 USP45 0 0 335 234 1 1
    USP33 XPA 0 0 107 365 1 1
    USP33 DERA 0 0 152 204 1 1
    USP33 ZFR 131 0 0 189 1 1
    USP33 RPS6KA5 0 0 70 293 1 1
    USP33 GPS1 0 0 0 191 1 1
    USP33 RHOXF2B 0 0 265 281 1 1
    USP33 TRPM7 0 0 51 179 1 1
    USP33 HIF1A 0 0 316 316 1 2
    USP33 SP1 0 0 120 202 1 1
    USP33 TRIM66 0 0 134 294 1 1
    USP33 SELENBP1 297 0 777 838 1 1
    USP33 UBE2R2 0 0 122 210 1 1
    USP33 USP41 0 0 324 230 1 1
    USP33 CDK2 0 0 120 174 1 1
    USP33 EXOC8 0 0 325 630 1 1
    USP33 ARFIP1 0 0 144 348 1 1
    USP33 MRPS6 0 0 0 267 1 1
    USP33 SMARCAD1 0 0 0 167 1 1
    USP33 RPL13A 0 0 0 188 1 1
    USP33 MYO9B 0 0 150 220 1 1
    USP33 MYSM1 0 0 294 487 1 1
    USP33 CCNF 0 0 325 558 1 1
    USP33 UBE2A 0 0 203 321 1 1
    USP33 MRPL13 0 0 0 298 1 1
    USP33 USP37 0 0 384 452 1 1
    USP33 CFTR 0 0 95 256 1 1
    USP33 TTBK2 0 0 141 495 1 1
    USP33 RNF40 0 0 0 173 1 1
    USP33 UCHL5 0 0 324 440 1 1
    USP33 RPS16 0 0 0 189 1 1
    USP33 MRPL43 0 0 0 266 1 1
    USP33 ZNF44 0 0 320 334 1 1
    USP33 MRPL46 0 0 0 250 1 1
    USP33 RBM3 0 0 0 186 1 1
    USP33 EIF3H 0 0 256 290 1 1
    USP33 ZFYVE19 0 0 55 154 1 1
    USP33 NPRL2 0 0 0 379 1 1
    USP33 HGS 0 0 125 217 1 2
    USP33 CCDC36 0 0 0 185 1 1
    USP33 USP17L29 0 0 324 188 1 1
    USP33 ATP1B1 0 0 72 630 1 1
    USP33 MRPS11 0 0 0 161 1 1
    USP33 MYC 209 0 112 285 1 2
    USP33 ATXN7L3 0 0 54 158 1 1
    USP33 PPIP5K1 0 0 0 161 1 1
    USP33 HIST1H2BD 0 0 0 207 1 1
    USP33 NUDCD2 0 0 212 225 1 1
    USP33 UBE2D1 0 0 160 188 1 1
    USP33 AP4S1 0 0 150 392 1 1
    USP33 ARRDC2 0 0 155 154 1 1
    USP33 RNF168 0 0 95 251 1 1
    USP33 CTDSP1 0 0 0 180 1 1
    USP33 DHX33 0 0 0 192 1 1
    USP33 UBL5 0 0 0 192 1 1
    USP33 RUVBL2 0 0 0 166 1 1
    USP33 DZIP3 0 0 145 239 1 1
    USP33 CDYL 0 0 0 160 1 1
    USP33 RIOK1 0 0 112 173 1 1
    USP33 RPSAP58 0 0 0 153 1 1
    USP33 USP10 0 0 120 174 1 2
    USP33 CEP83 0 0 184 190 1 1
    USP33 MEF2D 0 0 114 154 1 1
    USP33 SRSF11 0 0 0 155 1 1
    USP33 UBA1 0 0 123 204 1 1
    USP33 CEP97 0 0 370 564 1 1
    USP33 UBD 0 0 108 160 1 1
    USP33 AGO4 0 0 67 185 1 1
    USP33 PSMB3 0 0 0 215 1 1
    USP33 UBE2K 0 0 102 412 1 1
    USP33 DYNC1I2 0 0 0 290 1 1
    USP33 PSMA6 0 0 0 162 1 1
    USP33 PCNT 0 0 157 259 1 1
    USP33 HIST1H2BM 0 0 0 207 1 1
    USP33 OTUB1 0 0 335 591 1 1
    USP33 RPS5 0 0 0 179 1 1
    USP33 KRIT1 0 0 0 185 1 1
    USP33 RCSD1 0 0 0 463 1 1
    USP33 CISH 0 0 144 197 1 1
    USP33 PDRG1 0 0 0 177 1 1
    USP33 RUVBL1 0 0 0 240 1 1
    USP33 HAUS1 0 0 61 198 1 1
    USP33 USP24 0 0 360 317 1 1
    USP33 NSMAF 0 0 124 294 1 1
    USP33 USP36 0 0 450 251 1 2
    USP33 SCLT1 0 0 183 183 1 1
    USP33 SPICE1 0 0 205 205 1 1
    USP33 RNF144B 0 0 140 227 1 1
    USP33 PLK2 0 0 90 307 1 1
    USP33 SLIT1 0 0 244 278 1 1
    USP33 PAN2 0 0 390 475 1 1
    USP33 FARP2 0 0 122 186 1 1
    USP33 SOS2 0 0 75 170 1 1
    USP33 RAB31 0 0 81 288 1 1
    USP33 RAD17 0 0 120 244 1 1
    USP33 MRPL11 0 0 57 395 1 1
    USP33 MRPS5 0 0 0 392 1 1
    USP33 SRGAP1 0 0 234 277 1 1
    USP33 CAMK2N1 0 0 103 177 1 1
    USP33 DHX34 0 0 0 192 1 1
    USP33 ZNF436 0 0 321 335 1 1
    USP33 UBE2U 0 0 0 163 1 1
    USP33 UCHL3 0 0 392 464 1 1
    USP33 USP28 270 0 404 633 1 1
    USP33 MRPL41 0 0 0 250 1 1
    USP33 ENPP2 0 0 47 229 1 1
    USP33 AUP1 0 540 0 540 1 1
    USP33 ROBO3 0 0 257 289 1 1
    USP33 BLVRB 0 0 91 182 1 1
    USP33 AKTIP 0 0 103 181 1 1
    USP33 HMGCS2 0 0 54 312 1 1
    USP33 DDX58 0 0 57 166 1 1
    USP33 ZNF763 0 0 321 335 1 1
    USP33 CEP152 0 0 167 167 1 1
    USP33 OTUB2 0 0 266 454 1 1
    USP33 PSMA4 0 0 0 163 1 1
    USP33 NIPSNAP3B 0 0 0 205 1 1
    USP33 GALNT18 0 0 123 281 1 1
    USP33 CUL5 0 0 181 370 1 1
    USP33 CNOT4 0 0 91 207 1 1
    USP33 PCDH19 0 0 81 656 1 1
    USP33 MRPS14 0 0 0 326 1 1
    USP33 RAB11FIP1 0 0 0 189 1 1
    USP33 PLA2G2D 0 0 87 178 1 1
    USP33 USP6 0 0 297 231 1 1
    USP33 RPL8 0 0 0 153 1 1
    USP33 OCA2 0 0 107 168 1 1
    USP33 ADSL 0 0 103 579 1 1
    USP33 AKAP9 0 0 0 248 1 1
    USP33 UBE2L3 0 0 156 184 1 1
    USP33 ABTB1 0 0 0 183 1 1
    USP33 VSX2 274 0 0 274 1 1
    USP33 UBE2N 0 0 101 171 1 1
    USP33 HIST1H2BL 0 0 0 207 1 1
    USP33 MPND 0 0 395 494 1 1
    USP33 CEP192 0 0 155 154 1 1
    USP33 SARAF 0 0 123 215 1 1
    USP33 HAUS6 0 0 96 236 1 1
    USP33 BRCC3 0 0 261 381 1 1
    USP33 FBXW7 0 0 153 188 1 1
    USP33 CCP110 270 600 615 881 1 1
    USP33 WRN 0 0 0 223 1 1
    USP33 SETD1A 0 0 0 183 1 1
    USP33 CEP135 0 0 205 209 1 1
    USP33 FBXO10 0 0 49 157 1 1
    USP33 ZNF629 0 0 321 335 1 1
    USP33 SAC3D1 0 0 0 192 1 1
    USP33 CHEK1 0 0 52 159 1 1
    USP33 RHBDD2 0 540 0 549 1 1
    USP33 CEACAM6 0 0 0 250 1 1
    USP33 CDC20 0 0 123 264 1 1
    USP33 ENSG00000268434 0 0 0 178 1 1
    USP33 USP17L30 0 0 324 188 1 1
    USP33 USP35 0 0 373 237 1 1
    USP33 SENP7 0 0 122 246 1 1
    USP33 USP50 0 0 401 208 1 1
    USP33 WDFY1 0 0 0 277 1 1
    USP33 SEL1L2 0 540 0 551 1 1
    USP33 USP40 0 0 263 229 1 1
    USP33 XPC 0 0 0 163 1 1
    USP33 WDFY2 0 0 123 680 1 1
    USP33 RPL4 0 0 0 189 1 1
    USP33 RNF182 0 0 97 150 1 1
    USP33 VCP 0 0 90 213 1 2
    USP33 USP4 0 0 470 262 1 1
    USP33 GTPBP4 0 0 0 158 1 1
    USP33 OTUD4 0 0 325 454 1 1
    USP33 PIKFYVE 0 0 0 153 1 1
    USP33 ERI3 0 0 171 228 1 1
    USP33 DHX16 0 0 0 160 1 1
    USP33 HIST3H2BB 0 0 0 207 1 1
    USP33 SEH1L 0 0 0 156 1 1
    USP33 DHX35 0 0 0 192 1 1
    USP33 CEP120 0 0 163 245 1 1
    USP33 USP3 0 0 393 338 1 1
    USP33 HIBCH 0 0 0 260 1 1
    USP33 PRPF39 0 0 0 205 1 1
    USP33 CDYL2 0 0 0 160 1 1
    USP33 HERC1 0 0 134 200 1 1
    USP33 LARP4B 0 0 134 214 1 1
    USP33 SRGAP3 0 0 134 282 1 1
    USP33 KRR1 131 0 0 186 1 1
    USP33 SLIT3 0 0 458 462 1 1
    USP33 HIST1H2BA 0 0 0 207 1 1
    USP33 MRPL33 0 0 0 260 1 1
    USP33 UBA5 0 0 113 174 1 1
    USP33 UBLCP1 0 0 0 277 1 1
    USP33 AKT1 0 0 113 160 1 2
    USP33 MARCH6 0 540 426 785 1 1
    USP33 UBE3A 0 0 285 345 1 1
    USP33 SLIT2 0 0 251 285 1 1
    USP33 USP46 0 0 427 250 1 1
    USP33 RPL23L 0 0 0 243 1 1
    USP33 SPATA5 0 0 0 170 1 1
    USP33 GDI2 0 0 0 267 1 1
    USP33 KLHL36 0 0 112 171 1 1
    USP33 USP1 0 0 564 344 1 1
    USP33 USP17L25 0 0 324 188 1 1
    USP33 SF3B1 0 0 0 155 1 1
    USP33 PIAS4 0 0 0 175 1 1
    USP33 BET1L 0 0 150 423 1 1
    USP33 KIF24 0 0 204 227 1 1
    USP33 HID1 0 0 0 152 1 1
    USP33 RBX1 0 360 287 574 1 1
    USP33 TSC2 0 0 72 275 1 2
    USP33 ECI2 0 0 0 184 1 1
    USP33 SMURF2 0 0 150 192 1 1
    USP33 TIMM44 0 0 90 294 1 1
    USP33 USP8 0 0 558 457 1 1
    USP33 SMARCC1 0 0 0 232 1 1
    USP33 DAP3 0 0 0 250 1 1
    USP33 RBM14-RBM4 0 0 0 357 1 1
    USP33 STAMBP 0 0 456 565 1 1
    USP33 YWHAB 0 0 90 253 1 1
    USP33 USP2 0 0 468 271 1 1
    USP33 KLHL7 0 0 57 173 1 1
    USP33 PAK1IP1 0 0 144 235 1 1
    USP33 YOD1 0 0 282 363 1 1
    USP33 VHL 486 540 614 905 1 1
    USP33 IQGAP3 0 0 0 160 1 1
    USP33 ROBO2 0 0 212 237 1 1
    USP33 MRPL19 0 0 0 271 1 1
    USP33 SAG 0 0 494 494 1 1
    USP33 GOLGA5 0 0 0 317 1 1
    USP33 UBL4A 0 0 108 198 1 1
    USP33 DOT1L 0 0 0 160 1 1
    USP33 FAM179B 0 0 0 164 1 1
    USP33 TTBK1 0 0 0 193 1 1
    USP33 ADRB2 486 600 576 905 1 1
    USP33 RCC1 0 0 122 218 1 1
    USP33 ZNF569 0 0 310 325 1 1
    USP33 HERC3 0 0 108 188 1 1
    USP33 ECHDC1 0 0 0 153 1 1
    USP33 EXOC1 0 0 0 242 1 1
    USP33 SV2B 0 0 92 627 1 1
    USP33 PSMA3 0 0 82 230 1 1
    USP33 BARD1 0 0 81 206 1 1
    USP33 ZNF507 0 0 0 317 1 1
    USP33 STXBP3 0 0 0 430 1 1
    USP33 AP2B1 0 0 141 179 1 1
    USP33 MCM7 0 0 0 170 1 1
    USP33 RASA1 0 0 47 570 1 1
    USP33 ATG2A 0 0 0 152 1 2
    USP33 BMPR2 0 0 0 199 1 1
    USP33 VAPB 237 0 0 253 1 1
    USP33 PIH1D1 0 0 0 166 1 1
    USP33 MRPL15 0 0 0 326 1 1
    USP33 RNF4 0 0 0 318 1 1
    USP33 ZFYVE26 0 0 107 262 1 1
    USP33 USP14 0 0 498 376 1 1
    USP33 ITCH 0 0 391 420 1 1
    USP33 FMR1 0 0 69 278 1 1
    USP33 ABCA2 0 0 74 221 1 1
    USP33 CLSTN1 0 0 123 275 1 1
    USP33 ARIH2 0 0 141 221 1 1
    USP33 DDX17 0 0 112 248 1 1
    USP33 UBL3 0 0 136 207 1 1
    USP33 SUPT5H 0 0 0 150 1 1
    USP33 HECW1 0 0 147 251 1 1
    USP33 USP26 0 0 391 454 1 1
    USP33 HIST1H2BF 0 0 0 207 1 1
    USP33 MRTO4 0 0 0 195 1 1
    USP33 TNFAIP3 0 0 155 357 1 1
    USP33 SUPT6H 0 0 0 152 1 1
    USP33 USP19 0 0 451 294 1 1
    USP33 CEP290 0 0 171 268 1 1
    USP33 SASS6 0 0 134 172 1 1
    USP33 UBC 487 900 93 952 1 1
    USP33 USP30 0 0 500 408 1 1
    USP33 ATP2B1 0 0 66 444 1 1
    USP33 DCAF15 0 0 181 181 1 1
    USP33 HIST1H2BE 0 0 0 207 1 1
    USP33 PLAA 0 0 66 169 1 1
    USP33 UBE3B 0 0 123 197 1 1
    USP33 SETD2 0 0 0 165 1 1
    USP33 ATP6AP1 0 0 90 256 1 1
    USP33 MSH2 0 0 0 227 1 1
    USP33 UBE2D2 0 0 90 157 1 1
    USP33 KIF3A 0 0 113 152 1 1
    USP33 RMDN2 0 0 202 251 1 1
    USP33 PDZRN3 0 0 164 163 1 1
    USP33 MRPL2 0 0 0 226 1 1
    USP33 RPL23 0 0 0 226 1 1
    USP33 OBFC1 218 0 0 223 1 1
    USP33 RPL27A 0 0 0 205 1 1
    USP33 KIAA0368 0 0 150 674 1 1
    USP33 CACUL1 0 0 0 229 1 1
    USP33 MRPS15 0 0 0 286 1 1
    USP33 DNAAF2 0 0 0 166 1 1
    USP33 PTCD1 0 0 0 165 1 1
    USP33 DNAJC11 0 0 56 452 1 1
    USP33 FBXL5 0 0 323 643 1 1
    USP33 H2BFS 0 0 0 207 1 1
    USP33 AMBRA1 0 0 154 182 1 2
    USP33 STX3 0 0 82 190 1 1
    USP33 UBR3 0 0 44 161 1 1
    USP33 UBE2O 0 0 73 209 1 1
    USP33 TRIM54 270 0 0 366 1 1
    USP33 RNF26 0 0 155 163 1 1
    USP33 RNF128 0 0 170 221 1 1
    USP33 UBE2S 0 0 97 171 1 1
    USP33 PSMB10 0 0 0 162 1 1
    USP33 JOSD1 0 0 390 556 1 1
    USP33 SMARCC2 0 0 0 164 1 1
    USP33 OTUD5 0 0 269 410 1 1
    USP33 SKAP2 0 0 85 161 1 1
    USP33 MRPL27 0 0 0 261 1 1
    USP33 CNKSR2 0 0 117 209 1 1
    USP33 FAM105A 98 0 60 152 1 1
    USP33 JOSD2 0 0 391 562 1 1
    USP33 ARRDC3 0 0 329 329 1 1
    USP33 WDR92 0 0 0 175 1 1
    USP33 RPS27A 0 900 0 903 1 1
    USP33 ARRB2 835 600 700 978 1 1
    USP33 RPS15 0 0 0 179 1 1
    USP33 CDC34 0 0 74 167 1 1
    USP33 ARRB1 270 600 323 785 1 1
    USP33 MRPL36 0 0 0 250 1 1
    USP33 UBA2 0 0 113 167 1 1
    USP33 PPM1B 0 0 92 237 1 1
    USP33 C18orf32 0 0 0 151 1 1
    USP33 HIST1H2BG 0 0 0 207 1 1
    USP33 MSR1 0 0 47 194 1 1
    USP33 MRPS16 0 0 0 326 1 1
    USP33 TBC1D3D 0 0 125 154 1 1
    USP33 DHX29 0 0 0 178 1 1
    USP33 CENPN 0 0 95 151 1 1
    USP33 ZFAND3 0 0 140 199 1 1
    USP33 USP20 270 900 819 927 1 1
    USP33 CCT6B 0 0 271 277 1 1
    USP33 BECN1 270 0 134 356 1 2
    USP33 AP1S1 0 0 113 283 1 1
    USP33 ENSG00000262660 0 0 0 173 1 1
    USP33 USP49 0 0 282 297 1 1
    USP33 HIST1H2BB 0 0 0 207 1 1
    USP33 SNX4 0 0 0 155 1 1
    USP33 DUSP1 270 0 0 285 1 1
    USP33 ATXN3 0 0 323 366 1 1
    USP33 UPF1 0 0 0 216 1 1
    USP33 LZTS2 0 0 150 280 1 1
    USP33 RPS14 0 0 0 161 1 1
    USP33 KRAS 128 0 46 152 1 1
    USP33 UEVLD 0 0 183 209 1 1
    USP33 TMUB1 0 0 62 240 1 1
    USP33 ZNRF2 0 0 51 171 1 1
    USP33 TCEB1 486 0 253 611 1 1
    USP33 ATP5MF-PTCD1 0 0 0 165 1 1
    USP33 ARRDC5 0 0 155 154 1 1
    USP33 RPS11 0 0 0 192 1 1
    USP33 ST7 226 0 0 242 1 1
    USP33 NSG1 0 0 156 155 1 1
    USP33 DBF4 0 0 0 168 1 1
    USP33 USP44 0 0 470 360 1 1
    USP33 USP9X 0 0 406 288 1 1
    USP33 NKTR 0 0 0 188 1 1
    USP33 NPEPPS 0 0 112 155 1 1
    USP33 POLR2A 0 0 242 291 1 1
    USP33 DIAPH1 0 0 108 210 1 1
    USP33 TRIP12 0 0 117 259 1 1
    USP33 IQGAP1 0 0 0 201 1 1
    USP33 USP27X 0 0 407 361 1 1
    USP33 PARP11 0 0 155 207 1 1
    USP33 PLK4 0 0 208 280 1 1
    USP33 RAB40AL 0 0 160 159 1 1
    USP33 USP47 0 0 451 281 1 1
    USP33 GAPDH 0 0 122 176 1 2
    USP33 MANEA 0 0 150 257 1 1
    USP33 DYNC1I1 0 0 123 386 1 1
    USP33 SMKR1 0 0 0 153 1 1
    USP33 RPL12 0 0 0 216 1 1
    USP33 ENSG00000260342 0 0 0 212 1 1
    USP33 NEDD4 0 0 394 434 1 2
    USP33 SART3 0 0 103 183 1 1
    USP33 DPCD 0 0 0 177 1 1
    USP33 UBE2G1 0 0 124 224 1 1
    USP33 OTUD3 0 0 203 257 1 1
    USP33 LRRC45 0 0 134 174 1 1
    USP33 CTNNB1 270 0 95 311 1 1
    USP33 RBM5 0 0 0 186 1 1
    USP33 MFN2 0 0 0 172 1 2
    USP33 DCAF6 0 0 0 193 1 1
    USP33 MRPL12 0 0 0 173 1 1
    USP33 ORC1 0 0 0 202 1 1
    USP33 USP21 270 0 317 432 1 1
    USP33 CXCR4 0 0 171 171 1 2
    USP33 NANS 0 0 134 208 1 1
    USP33 TAOK3 0 0 142 249 1 1
    USP33 PSMB4 0 0 0 213 1 1
    USP33 CEP170 0 0 95 224 1 1
    USP33 USP42 0 0 230 174 1 1
    USP33 RPL9 0 0 0 235 1 1
    USP33 USP17L27 0 0 324 188 1 1
    USP33 H2BFWT 0 0 0 207 1 1
    USP33 DNAJB4 0 0 90 172 1 1
    USP33 SYVN1 0 900 0 906 1 1
    USP33 TP53 0 0 189 207 1 2
    USP33 TMEM33 0 0 0 248 1 1
    USP33 MDM2 0 0 324 323 1 1
    USP33 SOX18 0 0 0 236 1 1
    USP33 USP17L26 0 0 324 188 1 1
    USP33 EPS15 0 0 112 203 1 1
    USP33 ANKFY1 0 0 134 410 1 1
    USP33 NEDD8 0 0 94 192 1 1
    USP33 FAM63A 0 0 181 198 1 1
    USP33 USP54 0 0 464 487 1 1
    USP33 RAF1 0 0 64 292 1 2
    USP33 CUL2 0 360 267 582 1 1
    USP33 RMDN3 0 0 102 302 1 1
    USP33 DOK3 0 0 112 184 1 1
    USP33 NOL6 0 0 0 166 1 1
    USP33 PSMA8 0 0 0 156 1 1
    USP33 EXOC2 270 0 127 387 1 1
    USP33 HDAC6 0 0 114 156 1 2
    USP33 GBF1 0 0 0 177 1 1
    USP33 CCNI 0 0 134 238 1 1
    USP33 HUWE1 0 0 181 213 1 1
    USP33 CEP76 0 0 166 235 1 1
    USP33 UBE4A 0 0 108 196 1 1
    USP33 ATP2B4 0 0 0 317 1 1
    USP33 MCOLN1 0 0 61 177 1 1
    USP33 HIST1H2BI 0 0 0 207 1 1
    USP33 DLGAP1 0 0 73 335 1 1
    USP33 B4GALT3 0 0 0 198 1 1
    USP33 UBE2H 0 0 161 220 1 1
    USP33 RAB11FIP5 0 0 98 197 1 1
    USP33 POLR2G 0 0 323 442 1 1
    USP33 ARR3 0 0 234 234 1 1
    USP33 PARK2 0 0 143 209 1 1
    USP33 RPL17-C18orf32 0 0 0 151 1 1
    USP33 DBF4B 0 0 0 168 1 1
    USP33 USP15 270 0 460 439 1 1
    USP33 PHYHIP 0 0 60 376 1 1
    USP33 EGLN3 0 0 60 159 1 1
    USP33 VAPA 130 0 0 196 1 1
    USP33 MRPS35 0 0 0 250 1 1
    USP33 DHX40 0 0 0 194 1 1
    USP33 KLHL21 0 0 53 167 1 1
    USP33 PDZRN4 0 0 208 208 1 1
    USP33 SRGAP2 0 0 134 159 1 1
    USP33 HIST1H2BH 0 0 0 207 1 1
    USP33 ZNF501 0 0 321 335 1 1
    USP33 USP17L1P 0 0 260 165 1 1
    USP33 CDC5L 0 0 0 153 1 1
    USP33 BRCA1 0 0 120 254 1 1
    USP33 STK11 0 0 54 456 1 2
    USP33 USP38 0 0 391 246 1 1
    USP33 USP39 0 0 407 285 1 1
    USP33 OPA1 0 0 0 190 1 1
    USP33 CEACAM8 0 0 47 307 1 1
    USP33 FBXO11 0 0 115 407 1 1
    USP33 FAM188B 0 0 170 179 1 1
    USP33 CTDSPL 0 0 0 180 1 1
    USP33 ATP6V0D2 0 0 74 189 1 1
    USP33 PCM1 0 0 73 157 1 1
    USP33 TRAF6 270 0 113 324 1 2
    USP33 CLSPN 0 0 181 240 1 1
    USP33 DHX36 0 0 0 178 1 1
    USP33 HIST2H2BF 0 0 0 207 1 1
    USP33 SENP1 0 0 95 158 1 1
    USP33 MRPL3 0 0 0 344 1 1
    USP33 USP22 0 0 465 384 1 1
    USP33 UBE4B 0 0 118 210 1 1
    USP33 ARL6IP5 0 0 107 171 1 1
    USP33 USP29 0 0 393 456 1 1
    USP33 MRPL20 0 0 0 250 1 1
    USP33 RPL17 0 0 0 151 1 1
    USP33 ATP6AP2 0 0 66 230 1 1
    USP33 FAM188A 0 0 150 159 1 1
    USP33 TUBD1 0 0 150 224 1 1
    USP33 SVIP 0 0 154 153 1 1
    USP33 MRPL24 0 0 0 313 1 1
    USP33 TRIM55 0 0 69 192 1 1
    USP33 OTULIN 0 0 138 174 1 1
    USP33 CUL1 0 0 213 370 1 1
    USP33 C1orf122 0 0 341 413 1 1
    USP33 OTUD6A 0 0 325 442 1 1
    USP33 IPO5 0 0 90 166 1 1
    USP33 RNF123 0 0 95 169 1 1
    USP33 UBOX5 0 0 181 246 1 1
    USP33 GGH 0 0 195 213 1 1
    USP33 HIST1H2BO 0 0 0 207 1 1
    USP33 USP32 0 0 391 258 1 1
    USP33 MIOS 0 0 0 158 1 1
    USP33 VPS26A 0 0 97 190 1 1
    USP33 VCPIP1 0 0 392 567 1 1
    USP33 USP17L24 0 0 324 188 1 1
    USP33 MARCH2 0 0 210 265 1 1
    USP33 MRPS7 0 0 0 179 1 1
    USP33 ATP6V0B 0 0 113 178 1 1
    USP33 SENP6 0 0 0 217 1 1
    USP33 WDR48 0 0 193 312 1 1
    USP33 UBE2G2 0 0 181 245 1 1
    USP33 RALB 270 0 457 632 1 1
    USP33 USP16 0 0 181 202 1 1
    USP33 ROBO1 835 900 637 993 1 1
    USP33 RNF8 0 0 113 202 1 1
    USP33 NIPSNAP3A 0 0 229 361 1 1
    USP33 CEP164 0 0 142 203 1 1
    USP33 STX1A 0 0 0 178 1 1
    USP33 STX6 0 0 81 164 1 1
    USP33 RPS2 0 0 0 287 1 1
    USP33 DNAJB5 0 0 0 228 1 1
    USP33 UBE2E1 0 0 123 186 1 1
    USP33 PIH1D2 0 0 0 166 1 1
    USP33 USP17L2 0 0 322 188 1 1
    USP33 SQSTM1 0 0 82 177 1 2
    USP33 STK38 0 0 92 197 1 1
    USP33 RANBP9 0 0 74 157 1 1
    USP33 EXOC5 0 0 0 269 1 1
    USP33 RBM4 0 0 55 366 1 1
    USP33 UFD1L 0 0 113 186 1 1
    USP33 CEP131 0 0 241 277 1 1
    USP33 DHX57 0 0 0 178 1 1
    USP33 IFIT5 131 0 0 150 1 1
    USP33 UBA6 0 0 65 170 1 1
    USP33 PRRG4 0 0 162 503 1 1
    USP33 ALG13 0 0 142 391 1 1
    USP33 CGRRF1 289 0 0 296 1 1
    USP33 HIST1H2BK 0 0 0 207 1 1
    USP33 MFN1 0 0 54 183 1 1
    USP33 UCHL1 0 0 292 415 1 1
    USP33 MAST2 0 0 0 154 1 1
    USP33 PRKACB 0 0 142 201 1 1
    USP33 VTA1 0 0 103 234 1 1
    USP33 OTUD6B 0 0 325 512 1 1
    USP33 WBSCR16 0 0 74 209 1 1
    USP33 MCM3AP 0 0 0 192 1 1
    USP33 RBM4B 0 0 0 288 1 1
    USP33 RPL3 0 0 0 203 1 1
    USP33 ARIH1 0 0 142 232 1 1
    USP33 NCOA4 0 0 91 490 1 1
    USP33 CETN2 0 0 124 199 1 1
    USP33 SMC3 0 0 0 194 1 1
    USP33 TPP2 0 0 102 200 1 1
    USP33 CYLD 0 0 233 277 1 1
    USP33 USP25 0 0 240 361 1 1
    USP33 ADRM1 0 0 92 160 1 1
    USP33 EP400NL 0 0 0 177 1 1
    USP33 PUS10 0 0 0 171 1 1
    USP33 CEP63 0 0 135 154 1 1
    USP33 TCEB2 270 540 276 797 1 1
    USP33 OTUD7A 0 0 325 440 1 1
    USP33 INO80 0 0 0 164 1 1
    USP33 FBF1 0 0 171 171 1 1
    USP33 NCAPD3 0 0 108 166 1 1
    USP33 USP53 0 0 391 411 1 1
    USP33 HIST1H2BN 0 0 0 207 1 1
    USP33 MRPL9 0 0 0 430 1 1
    USP33 WDTC1 0 0 0 193 1 1
    USP33 DERL2 0 540 0 561 1 1
    USP33 RPL26 0 0 0 190 1 1
    USP33 ECHS1 0 0 0 153 1 1
    USP33 WDR20 0 0 91 330 1 1
    USP33 SPATA5L1 0 0 0 170 1 1
    USP33 ENSG00000279392 0 0 156 184 1 1
    USP33 AHI1 0 0 0 398 1 1
    USP33 WSB1 0 0 556 685 1 1
    USP33 CNTROB 0 0 195 216 1 1
    USP33 UBTD1 0 0 205 235 1 1
    USP33 HIST1H2BJ 0 0 0 207 1 1
    USP33 SKP1 0 0 241 285 1 1
    USP33 ATG2B 0 0 0 152 1 2
    USP33 TBK1 0 0 63 185 1 2
    USP33 MRPL22 0 0 0 250 1 1
    USP33 RPL26L1 0 0 0 190 1 1
    USP33 YTHDC2 0 0 0 244 1 1
    USP33 DIO2 747 0 454 855 1 1
    USP33 USP7 0 0 503 385 1 1
    USP33 TBC1D3 0 0 134 162 1 1
    USP33 UBR1 0 0 108 163 1 1
    USP33 HAUS8 0 0 57 194 1 1
    USP33 MRPS2 0 0 0 250 1 1
    USP33 MRPS9 0 0 0 388 1 1
    USP33 MRPL16 0 0 0 226 1 1
    USP33 TAF1D 0 0 270 285 1 1
    USP33 SPINT2 205 0 0 205 1 1
    USP33 MRPL4 0 0 0 372 1 1
    USP33 STIL 0 0 180 179 1 1
    USP33 FBXW5 0 0 214 296 1 1
    USP33 WDR24 0 0 0 157 1 1
    USP33 USP12 0 0 458 264 1 1
    USP33 PSMD7 0 0 261 412 1 1
    USP33 BIRC6 0 0 0 202 1 1
    USP33 ATG3 0 720 0 726 1 2
    USP33 MRPS18A 0 0 0 243 1 1
    USP33 DHX30 0 0 0 178 1 1
    USP33 HIST2H2BE 0 0 90 248 1 1
    USP33 PPIP5K2 0 0 0 202 1 1
    USP33 UBE2I 0 0 145 224 1 1
    USP33 PAXBP1 0 0 0 186 1 1
    USP33 UBFD1 0 0 0 247 1 1
    USP33 MRPS12 0 0 0 190 1 1
    USP33 WIPF1 0 0 0 208 1 1
    USP33 PSMA7 0 0 0 156 1 1
    USP33 NADSYN1 0 0 0 203 1 1
    USP33 STX19 0 0 0 164 1 1
    USP33 UBB 0 900 46 906 1 1
    USP33 USP13 0 0 401 322 1 1
    USP33 GPC2 0 0 0 198 1 1
    USP33 HERC2 270 0 156 393 1 1
    USP33 USP5 0 0 460 630 1 1
    USP33 PAFAH1B1 0 0 66 248 1 1
    USP33 RBM7 0 0 0 189 1 1
    USP33 RPLP0 0 0 0 195 1 1
    USP33 CCNT2 0 0 0 189 1 1
    USP33 MRPL47 0 0 0 250 1 1
    USP33 CBLL1 0 0 160 178 1 1
    USP33 SHPRH 0 0 113 266 1 1
    USP33 USPL1 0 0 282 597 1 1
    USP33 UBE2J1 0 0 293 332 1 1
    USP33 IREB2 0 0 0 163 1 1
    USP33 CUL4B 0 0 0 179 1 1
    USP33 NEDD4L 0 0 212 235 1 1
    USP33 SOCS1 0 0 0 179 1 1
    USP33 PRPF38B 131 0 0 150 1 1
    USP33 WDFY3 0 0 134 275 1 2
    USP33 PRPF8 0 0 218 287 1 1
    USP33 ZCCHC17 0 0 0 192 1 1
    USP33 WDFY4 0 0 0 197 1 1
    USP33 DMWD 0 0 0 174 1 1
    USP33 UBE2J2 0 0 143 217 1 1
    USP33 USP18 0 0 214 195 1 1
    USP33 MRPL17 0 0 0 299 1 1
    USP33 ANTXR2 0 0 0 207 1 1
    USP33 DIO1 0 0 134 279 1 1
    USP33 GPX1 0 0 125 167 1 1
    USP33 FNIP1 0 0 0 164 1 1
    USP33 RALA 270 0 0 331 1 1
    USP33 PSMD14 0 0 231 355 1 1
    USP33 ATXN3L 0 0 342 384 1 1
    USP33 NEDD1 0 0 214 214 1 1
    USP33 NEK2 0 0 95 158 1 1
    USP33 SEL1L 0 720 0 727 1 1
    USP33 RPS18 0 0 0 290 1 1
    USP33 OTUD1 0 0 322 346 1 1
    USP33 RPS23 0 0 91 197 1 1
    USP33 NOVA1 0 0 70 187 1 1
    USP33 RNH1 0 0 49 170 1 1
    USP33 AVPR2 0 0 325 337 1 1
    USP33 DIO3 0 0 184 183 1 1
    USP33 MAPK6 0 0 65 209 1 1
    USP33 GPR149 0 0 143 278 1 1
    USP33 COPS5 0 0 368 555 1 1
    USP33 TP53BP1 0 0 66 183 1 1
    USP33 UBE2Q1 0 0 154 204 1 1
    USP33 KCTD19 0 0 82 155 1 1
    USP33 FAM179A 0 0 0 164 1 1
    USP33 NOSTRIN 0 0 125 284 1 1
    USP33 SRCAP 0 0 0 177 1 1
    USP33 DNM1L 0 0 0 175 1 2
    USP33 DET1 0 0 150 256 1 1
    USP33 RPS20 0 0 0 188 1 1
    USP33 H2BFM 0 0 0 207 1 1
    USP33 SENP8 0 0 104 194 1 1
    USP33 GABARAP 0 0 84 168 1 2
    USP33 RPS29 0 0 0 205 1 1
    USP33 FAM63B 0 0 193 210 1 1
    USP33 MEOX2 0 0 66 165 1 1
    USP33 UIMC1 0 0 74 252 1 1
    USP33 WSB2 0 0 95 355 1 1
    USP33 ENSG00000279624 0 0 108 163 1 1
    USP33 MRPL21 0 0 0 347 1 1
    USP33 UBA52 0 900 0 900 1 1
    USP33 ZNRF1 0 0 150 255 1 1
    USP33 NEURL4 270 0 468 669 1 1
    USP33 ATAD2B 0 0 0 208 1 1
    USP33 S1PR1 0 0 63 161 1 1
    USP33 ENSG00000214026 0 0 0 243 1 1
    USP33 RPS13 0 0 0 186 1 1
    USP33 CEP89 0 0 184 201 1 1
    USP33 EIF3F 0 0 74 203 1 1
    USP33 TRIM63 270 0 82 393 1 1
    USP33 ITGA2B 0 0 0 213 1 1
    USP33 VTI1B 0 0 66 279 1 2
    USP33 ENSG00000278299 0 0 133 161 1 1
    USP33 B4GALT1 0 0 0 198 1 1
    USP33 PSMB7 0 0 0 162 1 1
    USP33 MON2 0 0 0 198 1 1
    USP33 DERL3 0 540 0 558 1 1
    USP33 CNTLN 0 0 342 356 1 1
    USP33 EXOC4 0 0 0 211 1 1
    USP33 DHX8 0 0 0 192 1 1
    USP33 USP34 0 0 0 159 1 1
    USP33 TAC1 0 0 0 175 1 1
    USP33 MBIP 0 0 145 503 1 1
    USP33 RRM2 0 0 91 151 1 1
    USP33 STAMBPL1 0 0 317 454 1 1
    USP33 PBRM1 0 0 0 175 1 1
    USP33 PNISR 0 0 0 186 1 1
    USP33 ARHGAP39 0 0 365 427 1 1
    USP33 NINL 0 0 142 174 1 1
    USP33 MRPS18C 0 0 0 243 1 1
    USP33 TRIM44 0 0 95 163 1 1
    USP33 STAM 0 0 265 281 1 1
    USP33 CUL3 0 0 122 296 1 1
    USP33 QKI 0 0 70 230 1 1
    USP33 PSMA5 0 0 0 196 1 1
    USP33 GDI1 0 0 103 475 1 1
    USP33 USP11 0 0 467 290 1 1
    USP33 RRP7A 0 0 57 192 1 1
    USP33 USP48 0 0 371 267 1 1
    USP33 SETD1B 0 0 0 183 1 1
    USP33 B4GALT2 0 0 0 198 1 1
    USP33 COPS8 0 0 96 152 1 1
    USP33 OS9 0 900 0 901 1 1
    USP33 FBXO45 0 0 150 253 1 1
    USP33 RPSA 0 0 0 153 1 1
    USP33 TUBE1 0 0 231 301 1 1
    USP33 JADE1 0 0 324 340 1 1
    USP33 SNRK 0 0 0 256 1 1
    USP33 GNAI3 128 0 0 203 1 2
    USP33 SLC41A1 0 0 108 211 1 1
    USP33 UBE2E3 0 0 108 184 1 1
    USP33 RNF20 0 0 57 187 1 1
    USP33 OTUD7B 0 0 400 478 1 1
    USP33 ARRDC4 0 0 160 159 1 1
    USP33 DERL1 0 540 0 559 1 1
    USP33 ARF6 0 0 150 190 1 1
    USP33 USP51 0 0 460 352 1 1
    USP33 RPL3L 0 0 0 203 1 1
    USP33 TLR2 129 0 0 155 1 1
    USP33 CEP104 0 0 161 181 1 1
    USP33 PICK1 0 0 0 207 1 1
    USP33 TOLLIP 0 0 113 168 1 1
    USP33 BTRC 270 0 137 357 1 1
    USP33 NIN 0 0 155 177 1 1
    USP33 RPS15A 0 0 95 256 1 1
    USP33 HIST1H2BC 0 0 0 207 1 1
    USP33 GPR182 0 0 418 510 1 1
    USP33 RBM39 0 0 0 157 1 1
    USP33 COPS6 0 0 142 236 1 1
    USP33 HM13 0 0 124 225 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0001664 Molecular Function G protein-coupled receptor binding enables IPI
    GO:0004843 Molecular Function cysteine-type deubiquitinase activity enables IDA
    GO:0004843 Molecular Function cysteine-type deubiquitinase activity enables IMP
    GO:0004843 Molecular Function cysteine-type deubiquitinase activity enables TAS
    GO:0004197 Molecular Function cysteine-type endopeptidase activity enables IMP
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0031267 Molecular Function small GTPase binding enables IPI
    GO:0043130 Molecular Function ubiquitin binding NOT enables IDA
    GO:0008270 Molecular Function zinc ion binding enables IDA
    GO:0007411 Biological Process axon guidance involved_in ISS
    GO:0016477 Biological Process cell migration involved_in ISS
    GO:0009267 Biological Process cellular response to starvation involved_in IDA
    GO:0051298 Biological Process centrosome duplication involved_in IMP
    GO:0006897 Biological Process endocytosis involved_in IEA
    GO:0032091 Biological Process negative regulation of protein binding involved_in IMP
    GO:0007399 Biological Process nervous system development involved_in IBA
    GO:0032092 Biological Process positive regulation of protein binding involved_in IMP
    GO:0071108 Biological Process protein K48-linked deubiquitination involved_in IDA
    GO:0070536 Biological Process protein K63-linked deubiquitination involved_in IDA
    GO:0016579 Biological Process protein deubiquitination involved_in IDA
    GO:0016579 Biological Process protein deubiquitination involved_in IMP
    GO:0016579 Biological Process protein deubiquitination involved_in TAS
    GO:0050821 Biological Process protein stabilization involved_in IMP
    GO:0008277 Biological Process regulation of G protein-coupled receptor signaling pathway involved_in IBA
    GO:0008277 Biological Process regulation of G protein-coupled receptor signaling pathway involved_in IMP
    GO:0010506 Biological Process regulation of autophagy involved_in IMP
    GO:0006511 Biological Process ubiquitin-dependent protein catabolic process involved_in TAS
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0030891 Cellular Component VCB complex part_of TAS
    GO:0005813 Cellular Component centrosome located_in IDA
    GO:0005737 Cellular Component cytoplasm located_in TAS
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005925 Cellular Component focal adhesion located_in IDA
    GO:0043025 Cellular Component neuronal cell body located_in IEA
    GO:0005654 Cellular Component nucleoplasm located_in IDA
    GO:0048471 Cellular Component perinuclear region of cytoplasm located_in IDA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001377437 1 mRNA transcript variant 11 NC_000001 Reference
    NM_001377436 1 mRNA transcript variant 10 NC_000001 Reference
    NM_001377431 1 mRNA transcript variant 5 NC_000001 Reference
    NM_001377435 1 mRNA transcript variant 9 NC_000001 Reference
    NM_001377434 1 mRNA transcript variant 8 NC_000001 Reference
    NM_201624 3 mRNA transcript variant 2 NC_000001 Reference
    NM_001377438 1 mRNA transcript variant 12 NC_000001 Reference
    XM_047449735 1 mRNA transcript variant X2 NC_000001 Reference
    XM_047449731 1 mRNA transcript variant X1 NC_000001 Reference
    NM_001377430 1 mRNA transcript variant 4 NC_000001 Reference
    NM_001377433 1 mRNA transcript variant 7 NC_000001 Reference
    NM_001377432 1 mRNA transcript variant 6 NC_000001 Reference
    NM_015017 5 mRNA transcript variant 1 NC_000001 Reference
    NM_001377439 1 mRNA transcript variant 13 NC_000001 Reference
    NM_201626 3 mRNA transcript variant 3 NC_000001 Reference
    XM_011541056 3 mRNA transcript variant X3 NC_000001 Reference