SIRT2

sirtuin 2
General Information
Name sirtuin 2
Alias
  • NAD-dependent protein deacetylase sirtuin-2
  • NAD-dependent deacetylase sirtuin-2
  • NAD-dependent protein defatty-acylase sirtuin-2
  • SIR2-like protein 2
  • regulatory protein SIR2 homolog 2
  • silent information regulator 2
  • sir2-related protein type 2
  • sirtuin type 2
Synonyms SIR2 SIR2L SIR2L2
Gene_family Sirtuins
organism Homo sapiens
entrez_id 22933
location 19q13.2
transcript_count 7
exon_count 17
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
      Stringdb NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Functions in the antephase checkpoint preventing precocious mitotic entry in response to microtu [...]
      nextProt Deacetylates EP300, alpha-tubulin and histone H3 and H4.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    SIRT2 BioGRID FBXL6 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CCDC6 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID TP53 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CEBPB GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID YAP1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID RPA2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID RPA1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID RICTOR GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
    SIRT2 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SYVN1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID SIRT2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID MORC2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    SIRT2 BioGRID AHSA1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID BAG3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    SIRT2 BioGRID H2AC4 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID VDAC2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID TUFM GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID TPM2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SNRPD1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SRSF7 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RPL7 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RAN GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID KRT2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID HSPD1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SLC25A5 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ACTA2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID PARP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    SIRT2 BioGRID MAP2K1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID MCL1 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID ATRIP GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    SIRT2 BioGRID ATR GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID GSTT2B GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ZNF252P-AS1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SCFD2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID HORMAD2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID MTDH GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID NUDT12 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID NAA40 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID MOAP1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SLC22A23 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID GPAM GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID MANSC1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RAB3GAP2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID KIAA0930 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RAB3GAP1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID DEGS1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID VAMP7 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SNAI1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SARS1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RP9 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ORC2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID FADS1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID GSTT1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID DMD GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID CST5 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ART1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SHANK3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    SIRT2 BioGRID SEPTIN10 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID C11orf52 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID UTP4 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID PRPH GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID MARCKS GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID KRT19 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID KRT8 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID GFAP GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID DYNC1I2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CTNNA1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID ANK3 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID DERL1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID LAMTOR1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID BORCS6 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID HSD17B11 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID ANAPC2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID PHGDH GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID PANX1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID DCTN2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID ACTR2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID EBAG9 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID SQSTM1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID AGPS GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID REEP5 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID STIM1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CLIP1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CUL4A GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID GART GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID UNK GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID RMDN3 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID OCIAD1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID TBK1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID FBXL4 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID MTCH2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID ENTR1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID OXTR GeneID BioGRID Two-hybrid
    SIRT2 BioGRID IMMP2L GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID OTULINL GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID KAT2B GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID EZR GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID HIF1A GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    SIRT2 BioGRID RIOK1 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SPOP GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    SIRT2 BioGRID ARHGDIA GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID PLA2G4A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
    SIRT2 BioGRID CDK2 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID MDM2 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID GCKR GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID Kctd5 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID SCLT1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID FBF1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID CEP89 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID AHI1 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID TINF2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RPGRIP1L GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID BTRC GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS; Protein-peptide
    SIRT2 BioGRID PPP1CB GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ODF2 GeneID BioGRID Proximity Label-MS
    SIRT2 BioGRID RAD51 GeneID BioGRID Two-hybrid
    SIRT2 BioGRID TUBA4A GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID TRAPPC12 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    SIRT2 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western; Negative Genetic
    SIRT2 BioGRID ING1 GeneID BioGRID Affinity Capture-Western; Negative Genetic
    SIRT2 BioGRID H3C1 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID FOXO1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
    SIRT2 BioGRID ACLY GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID CBLB GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID CBL GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID CDC20 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID FZR1 GeneID BioGRID Biochemical Activity
    SIRT2 BioGRID RUNX3 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID PCK1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID HDAC6 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID tat GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    SIRT2 BioGRID RBP1 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID NUDT21 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID PAPOLA GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID DNAJB8 GeneID BioGRID Affinity Capture-Western
    SIRT2 BioGRID DNAJB6 GeneID BioGRID Affinity Capture-Western
    SIRT2 Protein SP140 GeneID HPRD None
    SIRT2 Protein KAT2B GeneID HPRD None
    SIRT2 Protein CDC14B GeneID HPRD None
    SIRT2 Protein KAT2A GeneID HPRD None
    SIRT2 Protein HDAC6 GeneID HPRD None
    SIRT2 Protein TUBA4A GeneID HPRD None
    SIRT2 Protein HOXA10 GeneID HPRD None
    SIRT2 BioGRID KRT78 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID RTN4 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID PHB2 GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID ELL GeneID BioGRID Affinity Capture-MS
    SIRT2 BioGRID GYS1 GeneID BioGRID Affinity Capture-MS
    StringDB
    A B experiments database textmining combined score hadb nhadb
    SIRT2 LHFPL3 0 0 46 192 1 1
    SIRT2 CBX1 0 0 193 438 1 1
    SIRT2 UBTF 0 0 212 244 1 1
    SIRT2 ACOX1 0 0 211 211 1 1
    SIRT2 CTSB 0 0 184 183 1 2
    SIRT2 NOX1 0 0 193 193 1 1
    SIRT2 TP53BP1 0 0 324 455 1 1
    SIRT2 MCL1 0 0 233 232 1 2
    SIRT2 SMARCA4 0 0 390 424 1 1
    SIRT2 SIRT1 270 900 882 946 1 2
    SIRT2 GNA11 0 0 66 157 1 1
    SIRT2 BACE1 0 0 282 319 1 1
    SIRT2 MAP3K5 0 0 193 193 1 1
    SIRT2 RBBP4 0 0 195 240 1 1
    SIRT2 HMGB1 0 0 207 239 1 2
    SIRT2 AFG3L2 0 0 44 155 1 1
    SIRT2 EHMT1 0 0 180 286 1 1
    SIRT2 ORC2 294 0 0 358 1 1
    SIRT2 LIPT1 0 0 0 174 1 1
    SIRT2 POLE3 0 0 0 193 1 1
    SIRT2 ATG5 0 0 405 428 1 2
    SIRT2 DUSP21 0 0 0 156 1 1
    SIRT2 HTATIP2 0 0 149 190 1 1
    SIRT2 TIA1 0 0 454 545 1 1
    SIRT2 SMC1B 0 0 0 184 1 1
    SIRT2 XBP1 0 0 217 218 1 2
    SIRT2 TPPP 0 0 229 263 1 1
    SIRT2 GRM2 0 0 91 176 1 1
    SIRT2 HIPK2 0 0 81 523 1 1
    SIRT2 FUS 0 0 167 167 1 1
    SIRT2 PTPN1 0 0 261 261 1 1
    SIRT2 RT14 0 0 310 314 1 1
    SIRT2 RANBP1 0 0 66 246 1 1
    SIRT2 PMPCB 0 0 48 184 1 1
    SIRT2 USP18 0 0 0 218 1 1
    SIRT2 SMEK2 0 0 294 323 1 1
    SIRT2 HSPB2 0 0 193 236 1 1
    SIRT2 HSPB1 0 0 235 276 1 1
    SIRT2 DYRK1A 0 0 147 341 1 1
    SIRT2 MGLL 0 0 108 197 1 1
    SIRT2 CHD3 0 0 135 183 1 1
    SIRT2 DUSP14 0 0 0 156 1 1
    SIRT2 POLE4 0 0 0 164 1 1
    SIRT2 FOXB1 0 0 0 166 1 1
    SIRT2 NFKBIB 0 0 105 160 1 1
    SIRT2 STMN1 0 0 180 191 1 1
    SIRT2 LIG1 0 0 73 154 1 1
    SIRT2 SOD3 0 0 235 259 1 1
    SIRT2 DNAJB8 270 0 85 315 1 1
    SIRT2 C4orf27 0 0 161 161 1 1
    SIRT2 GPX1 0 0 314 338 1 1
    SIRT2 TIAL1 0 0 0 173 1 1
    SIRT2 KDM5B 0 0 174 239 1 1
    SIRT2 RCOR1 0 0 585 585 1 1
    SIRT2 NUDT16 0 0 155 154 1 1
    SIRT2 IDH2 0 0 459 478 1 1
    SIRT2 CTSD 0 0 150 224 1 2
    SIRT2 AXIN1 0 0 205 205 1 1
    SIRT2 MRE11A 0 0 46 241 1 1
    SIRT2 ATM 0 0 459 512 1 1
    SIRT2 SHC1 0 0 142 201 1 1
    SIRT2 SMAD5 0 0 74 208 1 1
    SIRT2 SLC17A1 0 0 454 454 1 1
    SIRT2 EZR 129 0 57 150 1 1
    SIRT2 G6PD 270 0 299 473 1 1
    SIRT2 KLK6 0 0 291 290 1 1
    SIRT2 RAD23B 0 0 145 168 1 1
    SIRT2 BAZ2B 0 0 48 197 1 1
    SIRT2 POLI 0 0 509 535 1 1
    SIRT2 ENSG00000267261 0 0 0 191 1 1
    SIRT2 FOXN4 0 0 0 166 1 1
    SIRT2 AGRP 0 0 246 245 1 1
    SIRT2 NAA40 0 0 113 402 1 1
    SIRT2 ATG7 0 0 765 798 1 2
    SIRT2 EGLN2 0 0 143 191 1 1
    SIRT2 ORC5 0 0 150 192 1 1
    SIRT2 RRP8 0 900 107 906 1 1
    SIRT2 RECQL4 0 0 74 229 1 1
    SIRT2 ACTG1 0 0 180 212 1 1
    SIRT2 IKZF1 0 0 107 153 1 1
    SIRT2 CMPK2 0 0 0 180 1 1
    SIRT2 FMN1 0 0 84 161 1 1
    SIRT2 MTDH 294 0 68 313 1 2
    SIRT2 CPT1C 0 0 166 171 1 1
    SIRT2 GFAP 0 0 146 202 1 2
    SIRT2 CHD4 0 0 171 217 1 1
    SIRT2 RBPJ 0 0 113 193 1 1
    SIRT2 PPARGC1B 0 0 141 194 1 1
    SIRT2 KDM4D 0 0 181 193 1 1
    SIRT2 NAMPT 0 900 757 979 1 1
    SIRT2 HIST1H3A 488 0 70 578 1 1
    SIRT2 GABARAP 0 0 145 219 1 2
    SIRT2 TXN2 0 0 257 273 1 1
    SIRT2 VEGFA 0 0 375 375 1 1
    SIRT2 KDM5C 0 0 194 258 1 1
    SIRT2 DYRK4 0 0 0 189 1 1
    SIRT2 MBP 0 0 242 264 1 1
    SIRT2 PTEN 0 0 391 464 1 2
    SIRT2 NCOA6 0 0 0 183 1 1
    SIRT2 VILL 0 0 0 207 1 1
    SIRT2 WIPI1 0 0 134 254 1 2
    SIRT2 SRCAP 0 0 143 270 1 1
    SIRT2 DNM1L 0 0 325 385 1 2
    SIRT2 MYOD1 270 0 336 498 1 1
    SIRT2 ISOC1 0 0 0 264 1 1
    SIRT2 H2BFM 0 0 0 170 1 1
    SIRT2 CLPB 0 0 61 186 1 1
    SIRT2 ATAD2B 0 0 0 238 1 1
    SIRT2 HIST1H3C 0 0 160 286 1 1
    SIRT2 PHF6 0 0 0 165 1 1
    SIRT2 HFE 0 0 45 189 1 1
    SIRT2 NFKBIA 0 0 270 314 1 1
    SIRT2 LEP 0 0 394 394 1 1
    SIRT2 C12orf5 0 0 228 261 1 1
    SIRT2 SDCCAG3 236 0 0 236 1 1
    SIRT2 PARP16 0 0 247 246 1 1
    SIRT2 MAPK14 0 0 167 196 1 1
    SIRT2 LMNB2 0 0 207 234 1 1
    SIRT2 NDUFA9 0 0 420 472 1 1
    SIRT2 SLC36A4 0 0 46 458 1 1
    SIRT2 UCP1 0 0 375 421 1 1
    SIRT2 SREBF1 0 0 410 431 1 2
    SIRT2 HIST1H4A 0 0 686 745 1 1
    SIRT2 SETD1B 0 0 91 276 1 1
    SIRT2 TET1 0 0 292 292 1 1
    SIRT2 ISYNA1 0 0 141 157 1 1
    SIRT2 GDF11 0 0 184 183 1 1
    SIRT2 TIPARP 0 0 181 181 1 1
    SIRT2 TIMELESS 0 0 81 249 1 1
    SIRT2 HSPA4L 0 0 0 164 1 1
    SIRT2 QKI 0 0 146 194 1 1
    SIRT2 VIL1 0 0 0 207 1 1
    SIRT2 ATG12 0 0 245 281 1 2
    SIRT2 SUDS3 0 0 150 192 1 1
    SIRT2 PRMT7 0 0 134 168 1 1
    SIRT2 CDC27 270 0 124 357 1 1
    SIRT2 DAXX 0 0 158 157 1 1
    SIRT2 NQO1 0 0 294 298 1 1
    SIRT2 KAT8 0 0 391 509 1 2
    SIRT2 GFPT1 0 0 74 161 1 1
    SIRT2 HAAO 0 0 113 168 1 1
    SIRT2 ESRRG 0 0 139 184 1 1
    SIRT2 TRPM2 0 0 170 169 1 1
    SIRT2 DTYMK 0 0 43 182 1 1
    SIRT2 HSPB8 0 0 150 172 1 2
    SIRT2 HSPA1B 0 0 0 196 1 1
    SIRT2 PITPNM3 0 0 0 191 1 1
    SIRT2 PHB2 62 0 164 211 1 1
    SIRT2 GPI 0 0 114 162 1 1
    SIRT2 POLR1A 0 0 57 213 1 1
    SIRT2 YWHAH 0 0 60 193 1 1
    SIRT2 IQCB1 0 0 0 151 1 1
    SIRT2 HDAC1 0 0 760 853 1 2
    SIRT2 AK1 0 0 390 407 1 1
    SIRT2 FBP1 0 0 165 219 1 1
    SIRT2 MT-CO2 0 0 120 158 1 1
    SIRT2 HIST3H3 0 0 0 185 1 1
    SIRT2 DHFR 0 0 161 210 1 1
    SIRT2 DLAT 0 0 112 191 1 1
    SIRT2 HAT1 0 0 252 333 1 1
    SIRT2 TRIM44 0 0 261 307 1 1
    SIRT2 HIST1H3I 0 0 70 210 1 1
    SIRT2 CUL3 0 0 162 262 1 1
    SIRT2 HIST2H4A 0 0 686 745 1 1
    SIRT2 FABP4 0 0 193 193 1 1
    SIRT2 SFN 0 0 74 205 1 1
    SIRT2 ERCC1 0 0 181 205 1 1
    SIRT2 PBRM1 0 0 96 237 1 1
    SIRT2 XRCC5 0 0 340 422 1 1
    SIRT2 ST14 0 0 323 323 1 1
    SIRT2 DUSP3 0 0 63 175 1 1
    SIRT2 RANGRF 0 0 47 238 1 1
    SIRT2 TPTE2 0 0 0 156 1 1
    SIRT2 FOXO1 675 0 987 996 1 2
    SIRT2 HIST1H2BC 0 0 0 170 1 1
    SIRT2 EPAS1 0 0 123 155 1 2
    SIRT2 SLC25A33 0 0 261 288 1 1
    SIRT2 SOD2 0 0 565 618 1 1
    SIRT2 GPX2 0 0 90 164 1 1
    SIRT2 CDK9 0 0 287 286 1 1
    SIRT2 HSPA5 0 0 210 312 1 2
    SIRT2 FOXP2 0 0 56 179 1 1
    SIRT2 E2F1 0 0 170 188 1 1
    SIRT2 AVPR1A 0 0 0 215 1 1
    SIRT2 DNM1 0 0 125 201 1 1
    SIRT2 HIST1H3J 0 0 70 210 1 1
    SIRT2 SMYD2 0 0 126 239 1 1
    SIRT2 BTRC 129 0 96 196 1 1
    SIRT2 TADA3 0 0 181 229 1 1
    SIRT2 ADPRHL2 0 0 505 553 1 1
    SIRT2 LMO2 0 0 273 305 1 1
    SIRT2 MSTN 0 0 172 171 1 1
    SIRT2 HEY2 0 0 92 179 1 1
    SIRT2 YWHAZ 0 0 216 327 1 1
    SIRT2 FOS 0 0 277 333 1 1
    SIRT2 MAT1A 0 0 215 236 1 1
    SIRT2 TTLL5 0 0 82 192 1 1
    SIRT2 AIFM3 0 0 0 177 1 1
    SIRT2 MOBP 0 0 181 227 1 1
    SIRT2 OTC 0 0 171 171 1 1
    SIRT2 CDT1 0 0 155 154 1 1
    SIRT2 RNF20 0 0 282 328 1 1
    SIRT2 TTLL4 0 0 108 199 1 1
    SIRT2 PARP2 0 0 458 472 1 1
    SIRT2 CNP 0 0 181 373 1 1
    SIRT2 ANKRD45 0 0 0 164 1 1
    SIRT2 CDKN2B 0 0 151 203 1 1
    SIRT2 PIK3CB 0 0 74 163 1 1
    SIRT2 TLR2 0 0 148 162 1 1
    SIRT2 PMAIP1 0 0 218 218 1 1
    SIRT2 GRIN2B 0 0 152 159 1 1
    SIRT2 LRRK2 0 0 282 323 1 2
    SIRT2 NHSL1 0 0 66 209 1 1
    SIRT2 PHB 0 0 142 172 1 1
    SIRT2 MAOB 0 0 181 249 1 1
    SIRT2 ADCY10 0 0 161 180 1 1
    SIRT2 FOXI2 0 0 0 166 1 1
    SIRT2 PARP4 0 0 212 233 1 1
    SIRT2 CLPP 0 0 155 199 1 1
    SIRT2 PPP1R9B 0 0 0 181 1 1
    SIRT2 CPT1A 0 0 195 200 1 1
    SIRT2 HIST1H4C 160 0 686 777 1 1
    SIRT2 HSPH1 0 0 0 164 1 1
    SIRT2 UQCRFS1 0 0 135 202 1 1
    SIRT2 VCAM1 0 0 189 189 1 1
    SIRT2 SUMO1 0 0 184 205 1 1
    SIRT2 TNKS2 0 0 267 321 1 1
    SIRT2 MSS51 0 0 46 153 1 1
    SIRT2 SSH2 0 0 0 156 1 1
    SIRT2 ACACB 0 0 154 169 1 1
    SIRT2 CDK8 0 0 108 155 1 1
    SIRT2 NTRK2 0 0 167 187 1 1
    SIRT2 KMT2D 0 0 180 286 1 1
    SIRT2 NADK 0 0 310 433 1 1
    SIRT2 DROSHA 0 0 150 212 1 1
    SIRT2 NOX4 0 0 274 280 1 1
    SIRT2 ING1 270 0 203 592 1 1
    SIRT2 MAG 0 0 167 209 1 1
    SIRT2 FOXH1 0 0 44 168 1 1
    SIRT2 CEP63 0 0 45 195 1 1
    SIRT2 GRM5 0 0 60 224 1 1
    SIRT2 PINK1 0 0 403 467 1 2
    SIRT2 BCL6 0 0 260 318 1 1
    SIRT2 GPT 0 0 172 171 1 1
    SIRT2 SSRP1 0 0 120 220 1 1
    SIRT2 PHGDH 0 0 286 291 1 1
    SIRT2 RTN4 130 0 60 174 1 1
    SIRT2 BSCL2 0 0 0 216 1 1
    SIRT2 PHF20 0 0 0 166 1 1
    SIRT2 EIF4EBP1 0 0 280 289 1 1
    SIRT2 TYMS 0 0 122 157 1 1
    SIRT2 MACROD2 0 0 325 460 1 1
    SIRT2 EP400NL 0 0 0 183 1 1
    SIRT2 SNUPN 0 0 54 218 1 1
    SIRT2 HSP90AB1 0 0 59 160 1 2
    SIRT2 FOXO4 0 0 458 528 1 1
    SIRT2 CHTF18 0 0 123 168 1 1
    SIRT2 HIST1H2BN 0 0 0 170 1 1
    SIRT2 GPR183 0 0 305 305 1 1
    SIRT2 SMC6 0 0 63 166 1 1
    SIRT2 FOXQ1 0 0 0 166 1 1
    SIRT2 CCDC101 0 0 156 178 1 1
    SIRT2 ITM2B 0 0 0 175 1 1
    SIRT2 TH 0 0 229 256 1 1
    SIRT2 DENR 0 0 150 185 1 1
    SIRT2 DHODH 0 0 150 179 1 1
    SIRT2 CD34 0 0 166 165 1 1
    SIRT2 NGF 0 0 233 250 1 1
    SIRT2 FOXF1 0 0 54 177 1 1
    SIRT2 NCAPD3 0 0 95 192 1 1
    SIRT2 FOXJ1 0 0 0 166 1 1
    SIRT2 APOE 0 0 341 341 1 1
    SIRT2 FOXO3 0 0 759 817 1 2
    SIRT2 VDAC3 0 0 167 167 1 1
    SIRT2 SLC2A4 0 0 392 410 1 1
    SIRT2 CRY1 0 0 290 360 1 1
    SIRT2 PAPD7 0 0 71 187 1 1
    SIRT2 POLB 0 0 235 251 1 1
    SIRT2 CDC42 0 0 170 169 1 1
    SIRT2 CRTC1 0 0 181 260 1 1
    SIRT2 MPHOSPH8 0 0 67 273 1 1
    SIRT2 CRAT 0 0 184 183 1 1
    SIRT2 TXNDC9 0 0 216 216 1 1
    SIRT2 PARP9 0 0 252 283 1 1
    SIRT2 JDP2 0 0 52 652 1 1
    SIRT2 CDKN3 0 0 261 349 1 1
    SIRT2 DNAJB1 0 0 218 231 1 2
    SIRT2 ATG3 0 0 211 222 1 2
    SIRT2 HNF4A 0 0 243 334 1 1
    SIRT2 COMT 0 0 108 153 1 1
    SIRT2 TUBB2A 0 900 88 910 1 1
    SIRT2 ASPN 0 0 260 272 1 1
    SIRT2 PRDM2 0 0 156 155 1 1
    SIRT2 TBK1 273 0 85 314 1 2
    SIRT2 PNP 0 900 181 922 1 1
    SIRT2 MDH2 0 0 181 259 1 1
    SIRT2 HIST1H4D 0 0 686 745 1 1
    SIRT2 GEMIN6 0 0 172 171 1 1
    SIRT2 FOXP3 0 0 181 287 1 1
    SIRT2 SKP1 0 0 147 193 1 1
    SIRT2 PRMT5 0 0 285 310 1 1
    SIRT2 HIST1H2BJ 0 0 67 192 1 1
    SIRT2 RNF2 0 0 134 164 1 1
    SIRT2 YY1 0 0 289 301 1 1
    SIRT2 DDB1 0 0 173 227 1 1
    SIRT2 STAT5B 0 0 151 150 1 1
    SIRT2 VDAC1 0 0 300 300 1 2
    SIRT2 VAMP7 271 0 0 283 1 1
    SIRT2 SBF2 0 0 0 284 1 1
    SIRT2 USP7 0 0 150 173 1 1
    SIRT2 TEP1 0 0 0 173 1 1
    SIRT2 PITPNB 0 0 0 254 1 1
    SIRT2 PRKCD 0 0 180 179 1 2
    SIRT2 PGP 0 0 0 213 1 1
    SIRT2 HAP1 0 0 113 174 1 1
    SIRT2 PARP10 0 0 292 292 1 1
    SIRT2 OXCT1 0 0 141 194 1 1
    SIRT2 FOXD2 0 0 47 171 1 1
    SIRT2 RIPK3 0 0 921 921 1 1
    SIRT2 VPRBP 0 0 74 175 1 1
    SIRT2 NADSYN1 0 900 118 923 1 1
    SIRT2 GBA 0 0 113 164 1 1
    SIRT2 ELL 262 0 61 277 1 1
    SIRT2 TUBA1A 0 0 90 174 1 1
    SIRT2 NR1D1 0 0 283 282 1 2
    SIRT2 CD38 0 650 504 818 1 1
    SIRT2 PITPNM2 0 0 0 191 1 1
    SIRT2 OPALIN 0 0 125 167 1 1
    SIRT2 HIST2H4B 0 0 686 745 1 1
    SIRT2 SMYD4 0 0 0 165 1 1
    SIRT2 RHEB 0 0 242 241 1 2
    SIRT2 AHCY 0 0 181 181 1 1
    SIRT2 BMP5 0 0 0 459 1 1
    SIRT2 ENSG00000264813 0 0 207 207 1 1
    SIRT2 AOX1 0 0 198 209 1 1
    SIRT2 FADS1 294 0 51 302 1 1
    SIRT2 NSMCE2 0 0 157 196 1 1
    SIRT2 MCM10 0 0 150 327 1 1
    SIRT2 FOXP4 0 0 0 166 1 1
    SIRT2 FH 0 0 300 328 1 1
    SIRT2 DMAP1 0 0 134 152 1 1
    SIRT2 TXN 0 0 427 439 1 1
    SIRT2 PECAM1 0 0 135 152 1 1
    SIRT2 IDE 0 0 242 284 1 1
    SIRT2 CLK1 0 0 81 155 1 1
    SIRT2 SCFD2 286 0 0 286 1 1
    SIRT2 EIF4E 0 0 184 201 1 1
    SIRT2 HIST2H2BE 0 0 561 620 1 1
    SIRT2 PRKDC 0 0 227 303 1 2
    SIRT2 KAT2B 486 0 669 863 1 1
    SIRT2 YWHAQ 0 0 174 291 1 1
    SIRT2 OLIG2 0 0 154 202 1 1
    SIRT2 IPO9 0 0 73 232 1 1
    SIRT2 PRPS2 0 0 0 151 1 1
    SIRT2 STYXL1 0 0 57 170 1 1
    SIRT2 HMGCR 0 0 210 287 1 1
    SIRT2 GPR17 0 0 123 288 1 1
    SIRT2 NOS3 0 0 459 471 1 1
    SIRT2 ANKLE2 0 900 90 908 1 1
    SIRT2 CCND1 0 0 337 337 1 1
    SIRT2 PRDX2 0 0 155 169 1 1
    SIRT2 HIST1H4H 0 0 687 746 1 1
    SIRT2 ACMSD 0 0 158 157 1 1
    SIRT2 CUL4B 0 0 66 177 1 1
    SIRT2 KMT2A 0 0 137 249 1 1
    SIRT2 SFRP4 0 0 66 165 1 1
    SIRT2 GEN1 0 0 48 174 1 1
    SIRT2 FGF2 0 0 207 207 1 1
    SIRT2 RELB 0 0 170 169 1 2
    SIRT2 FOXK2 0 0 60 182 1 1
    SIRT2 PKM 0 0 341 367 1 1
    SIRT2 GSTM5 0 0 113 159 1 1
    SIRT2 RPS19BP1 0 0 395 394 1 1
    SIRT2 RAB3GAP1 271 0 0 286 1 1
    SIRT2 GADD45A 0 0 283 295 1 1
    SIRT2 CCND3 0 0 113 158 1 1
    SIRT2 GFOD2 0 0 0 165 1 1
    SIRT2 IGF1 0 0 605 605 1 1
    SIRT2 HIST1H3H 0 0 70 210 1 1
    SIRT2 MAPK1 0 0 140 174 1 2
    SIRT2 SUV39H2 0 0 203 306 1 1
    SIRT2 APOB 0 0 120 180 1 1
    SIRT2 HSPA13 0 0 0 164 1 1
    SIRT2 HSPA2 0 0 51 173 1 1
    SIRT2 TIPIN 0 0 0 193 1 1
    SIRT2 DCK 0 0 145 198 1 1
    SIRT2 UCP3 0 0 246 307 1 1
    SIRT2 DUSP26 0 0 0 180 1 1
    SIRT2 HIPK3 0 0 74 225 1 1
    SIRT2 BDNF 0 0 420 420 1 2
    SIRT2 GTF3C4 0 0 124 164 1 1
    SIRT2 GLS2 0 0 161 165 1 1
    SIRT2 BAHD1 0 900 0 900 1 1
    SIRT2 IDH3A 0 0 91 163 1 1
    SIRT2 ACADM 0 0 180 179 1 1
    SIRT2 FOXR1 0 0 0 166 1 1
    SIRT2 MUTYH 0 0 65 189 1 1
    SIRT2 RAVER1 0 0 0 151 1 1
    SIRT2 CBSL 0 0 155 154 1 1
    SIRT2 EGF 0 0 260 260 1 1
    SIRT2 SENP1 0 0 117 177 1 1
    SIRT2 IGFBP1 0 0 181 181 1 1
    SIRT2 PHF20L1 0 0 0 190 1 1
    SIRT2 ATP5A1 0 0 108 250 1 1
    SIRT2 GAK 0 0 49 292 1 1
    SIRT2 CDC6 0 0 206 393 1 1
    SIRT2 PAICS 0 0 460 508 1 1
    SIRT2 SLC1A2 0 0 120 156 1 1
    SIRT2 PDP1 0 0 120 197 1 1
    SIRT2 HIST2H2BF 0 0 0 170 1 1
    SIRT2 CYCS 0 0 459 488 1 1
    SIRT2 DUSP12 0 0 81 199 1 1
    SIRT2 CYP2E1 0 0 148 155 1 1
    SIRT2 HSPB3 0 0 194 200 1 1
    SIRT2 XPO5 0 0 108 192 1 1
    SIRT2 LPL 0 0 157 156 1 1
    SIRT2 ACHE 0 0 206 206 1 1
    SIRT2 NAP1L5 0 0 0 192 1 1
    SIRT2 CETP 0 0 81 158 1 1
    SIRT2 PPARA 0 0 507 526 1 1
    SIRT2 TRPC4AP 0 0 68 177 1 1
    SIRT2 USP22 0 0 96 185 1 1
    SIRT2 PITPNC1 0 0 0 191 1 1
    SIRT2 HSPA4 0 0 681 722 1 1
    SIRT2 POLR1E 0 0 265 286 1 1
    SIRT2 SMARCA2 0 0 372 407 1 1
    SIRT2 GATA4 0 0 184 183 1 2
    SIRT2 UBE4B 0 0 166 191 1 1
    SIRT2 DICER1 0 0 289 363 1 1
    SIRT2 PRPS1L1 0 0 0 151 1 1
    SIRT2 DYRK3 0 0 129 411 1 1
    SIRT2 LPIN3 0 0 0 168 1 1
    SIRT2 H2AFY2 0 0 81 166 1 1
    SIRT2 BAZ1B 0 0 156 288 1 1
    SIRT2 TUFM 0 0 0 155 1 1
    SIRT2 SSH1 0 0 0 156 1 1
    SIRT2 GPX4 0 0 183 242 1 1
    SIRT2 BLVRA 0 0 57 179 1 1
    SIRT2 MTR 0 0 150 177 1 1
    SIRT2 NAP1L3 0 0 0 192 1 1
    SIRT2 SESN2 0 0 170 169 1 2
    SIRT2 KDM2A 0 0 150 282 1 1
    SIRT2 TNS4 0 0 0 156 1 1
    SIRT2 CCER2 0 0 147 165 1 1
    SIRT2 NMNAT3 0 650 506 844 1 1
    SIRT2 PHF8 0 0 134 249 1 1
    SIRT2 XRCC1 0 0 194 199 1 1
    SIRT2 SAMD1 0 0 0 227 1 1
    SIRT2 FRZB 0 0 181 268 1 1
    SIRT2 MAPK8 0 0 270 327 1 2
    SIRT2 BUB1B 270 0 677 761 1 1
    SIRT2 GFOD1 0 0 0 165 1 1
    SIRT2 HES7 0 0 0 279 1 1
    SIRT2 CDH1 0 0 286 286 1 1
    SIRT2 DUSP10 0 0 0 156 1 1
    SIRT2 CD33 0 0 291 290 1 1
    SIRT2 EPM2A 0 0 53 166 1 1
    SIRT2 IDH1 0 0 268 294 1 1
    SIRT2 AGER 0 0 155 154 1 1
    SIRT2 HIST1H2BO 0 0 0 170 1 1
    SIRT2 SIRT6 0 0 800 464 1 1
    SIRT2 DUSP8 0 0 0 156 1 1
    SIRT2 HSPA14 0 0 0 164 1 1
    SIRT2 MAP1B 0 0 123 161 1 1
    SIRT2 AVP 0 0 171 171 1 1
    SIRT2 NMNAT2 0 650 460 830 1 1
    SIRT2 PPP1CB 128 0 0 196 1 1
    SIRT2 H3F3B 0 0 75 257 1 1
    SIRT2 GATA1 0 0 202 202 1 1
    SIRT2 AANAT 0 0 95 177 1 1
    SIRT2 PDE4A 0 0 155 203 1 1
    SIRT2 DUSP9 0 0 0 156 1 1
    SIRT2 ERCC8 0 0 44 208 1 1
    SIRT2 PITPNM1 0 0 0 191 1 1
    SIRT2 CUL1 0 0 108 214 1 1
    SIRT2 CASP7 0 0 150 167 1 1
    SIRT2 DUSP7 0 0 0 156 1 1
    SIRT2 ELAVL1 0 0 227 226 1 1
    SIRT2 CCL2 0 0 310 309 1 2
    SIRT2 SGK2 0 0 91 235 1 1
    SIRT2 CDC23 0 0 112 168 1 1
    SIRT2 ALB 0 0 401 400 1 1
    SIRT2 SMAD3 0 0 236 587 1 1
    SIRT2 BPGM 0 0 51 150 1 1
    SIRT2 CRY2 0 0 200 279 1 1
    SIRT2 BIRC3 0 0 81 161 1 1
    SIRT2 SLBP 0 0 166 184 1 1
    SIRT2 REC8 0 0 46 158 1 1
    SIRT2 SNCAIP 0 0 233 280 1 2
    SIRT2 ADIPOR1 0 0 96 152 1 1
    SIRT2 CDK5 0 0 390 413 1 2
    SIRT2 CHD1 0 0 216 266 1 1
    SIRT2 EP300 675 0 634 895 1 1
    SIRT2 ACSS1 0 0 467 509 1 1
    SIRT2 PRMT6 0 0 124 159 1 1
    SIRT2 IL4 0 0 203 203 1 1
    SIRT2 ENSG00000267318 0 0 0 157 1 1
    SIRT2 MRPL10 0 0 209 232 1 1
    SIRT2 TPTE 0 0 47 161 1 1
    SIRT2 NMRK1 0 0 517 526 1 1
    SIRT2 ATP5O 0 0 122 155 1 1
    SIRT2 CRYZ 0 0 132 158 1 1
    SIRT2 PCK2 0 0 235 242 1 1
    SIRT2 BNIP3 0 0 309 333 1 2
    SIRT2 SQSTM1 0 0 280 295 1 2
    SIRT2 SLC16A1 0 0 150 169 1 1
    SIRT2 KLF15 0 0 164 178 1 1
    SIRT2 MAPK3 0 0 297 331 1 2
    SIRT2 MMP9 0 0 283 284 1 1
    SIRT2 CUL4A 0 0 71 182 1 1
    SIRT2 ING3 0 0 155 271 1 1
    SIRT2 HIST2H2AA 0 0 562 585 1 1
    SIRT2 YEATS4 0 0 171 211 1 1
    SIRT2 ARHGDIA 270 0 139 344 1 1
    SIRT2 WHSC1L1 0 0 117 231 1 1
    SIRT2 RAD21L1 0 0 0 154 1 1
    SIRT2 ATG13 0 0 186 186 1 2
    SIRT2 ATF2 0 0 113 182 1 1
    SIRT2 PSEN1 0 0 315 315 1 2
    SIRT2 CRP 0 0 247 246 1 1
    SIRT2 RANGAP1 0 0 66 156 1 1
    SIRT2 SOX2 0 0 241 255 1 1
    SIRT2 DES 0 0 334 339 1 1
    SIRT2 HDAC4 0 0 734 819 1 1
    SIRT2 HIST2H2AA3 0 0 562 585 1 1
    SIRT2 DHPS 0 0 181 200 1 1
    SIRT2 HSP90AA1 0 0 503 521 1 2
    SIRT2 SBF1 0 0 70 422 1 1
    SIRT2 CTBP1 0 0 235 283 1 1
    SIRT2 ICAM1 0 0 234 234 1 1
    SIRT2 ZMYND15 0 0 0 165 1 1
    SIRT2 SLC25A14 0 0 113 178 1 1
    SIRT2 TINF2 211 0 227 364 1 1
    SIRT2 SUV420H2 0 0 131 167 1 1
    SIRT2 TRAPPC4 0 0 320 337 1 1
    SIRT2 FOXA3 0 0 75 210 1 1
    SIRT2 SOX9 0 0 140 156 1 1
    SIRT2 GTF3C1 0 0 294 294 1 1
    SIRT2 YEATS2 0 0 128 170 1 1
    SIRT2 UMPS 0 0 0 166 1 1
    SIRT2 NAP1L6 0 0 0 192 1 1
    SIRT2 BAX 0 0 170 169 1 2
    SIRT2 SYN1 0 0 157 178 1 1
    SIRT2 CITED2 0 0 129 155 1 1
    SIRT2 AURKA 0 0 120 288 1 2
    SIRT2 DUSP16 0 0 0 156 1 1
    SIRT2 AR 0 0 284 311 1 1
    SIRT2 HIST1H3D 0 0 160 286 1 1
    SIRT2 TTLL7 0 0 67 165 1 1
    SIRT2 GSN 0 0 122 274 1 1
    SIRT2 CDKN1A 0 0 369 388 1 2
    SIRT2 ID4 0 0 124 155 1 1
    SIRT2 NEDD9 0 0 57 219 1 1
    SIRT2 NDUFB2 0 0 108 159 1 1
    SIRT2 NCOA3 0 0 234 279 1 1
    SIRT2 ENSG00000270024 0 0 0 157 1 1
    SIRT2 NUDT21 270 0 0 277 1 1
    SIRT2 RUNX3 270 0 150 352 1 1
    SIRT2 HIST1H2BK 0 0 0 170 1 1
    SIRT2 MFN1 0 0 318 361 1 1
    SIRT2 SMAD1 0 0 76 210 1 1
    SIRT2 IRS2 0 0 283 300 1 1
    SIRT2 CLIP4 0 0 0 185 1 1
    SIRT2 SORD 0 0 96 158 1 1
    SIRT2 SEPT4 0 0 112 164 1 1
    SIRT2 UCHL1 0 0 150 178 1 1
    SIRT2 TBL1X 0 0 193 253 1 1
    SIRT2 SOD1 0 0 393 421 1 1
    SIRT2 PARP14 0 0 209 242 1 1
    SIRT2 BMI1 0 0 195 212 1 1
    SIRT2 SMC1A 0 0 74 186 1 1
    SIRT2 SMC3 0 0 249 331 1 1
    SIRT2 ARNT 0 0 234 268 1 2
    SIRT2 FGF6 0 0 266 266 1 1
    SIRT2 CITED1 0 0 59 158 1 1
    SIRT2 COX6C 0 0 66 161 1 1
    SIRT2 H3F3C 0 0 0 229 1 1
    SIRT2 CDC14B 270 0 108 454 1 1
    SIRT2 INSIG2 0 0 108 177 1 1
    SIRT2 JAG1 0 0 70 227 1 1
    SIRT2 JUN 0 0 404 420 1 1
    SIRT2 ASF1A 0 0 536 639 1 1
    SIRT2 ASF1B 0 0 92 294 1 1
    SIRT2 TAF1 0 0 325 359 1 1
    SIRT2 FBL 0 0 233 257 1 1
    SIRT2 LONP2 0 0 73 156 1 1
    SIRT2 NTHL1 0 0 90 221 1 1
    SIRT2 CYP19A1 0 0 170 169 1 1
    SIRT2 DPYSL2 0 0 149 181 1 1
    SIRT2 PARD3B 0 0 0 187 1 1
    SIRT2 SLC16A4 0 0 167 167 1 1
    SIRT2 AIF1 0 0 144 182 1 1
    SIRT2 HIC1 0 0 294 306 1 1
    SIRT2 SIX4 0 0 84 177 1 1
    SIRT2 PIK3CG 0 0 63 150 1 1
    SIRT2 RERE 0 0 305 305 1 1
    SIRT2 CCNA2 0 0 758 794 1 1
    SIRT2 PRAM1 0 0 134 325 1 1
    SIRT2 NCOA2 0 0 150 188 1 1
    SIRT2 COX15 0 0 56 218 1 1
    SIRT2 NOS1 0 0 144 163 1 1
    SIRT2 NFKB1 0 0 125 196 1 1
    SIRT2 KAT6A 0 0 458 563 1 1
    SIRT2 RELA 270 0 414 561 1 1
    SIRT2 DUPD1 0 0 0 156 1 1
    SIRT2 STRADA 0 0 96 326 1 1
    SIRT2 KMT2E 0 0 108 249 1 1
    SIRT2 CARM1 0 0 283 311 1 1
    SIRT2 TRIM25 0 0 0 168 1 1
    SIRT2 BUB1 0 0 107 156 1 1
    SIRT2 GSTM3 0 0 0 192 1 1
    SIRT2 ART5 0 0 234 234 1 1
    SIRT2 FOXB2 0 0 0 166 1 1
    SIRT2 PDHA1 0 0 180 274 1 1
    SIRT2 HDAC10 0 0 662 767 1 1
    SIRT2 TCF7L2 0 0 141 180 1 1
    SIRT2 HIST4H4 0 0 686 745 1 1
    SIRT2 MAP2K7 0 0 240 239 1 1
    SIRT2 PML 0 0 174 191 1 1
    SIRT2 ENO1 0 0 207 212 1 1
    SIRT2 NNT 0 900 234 925 1 1
    SIRT2 DUSP5 0 0 75 202 1 1
    SIRT2 GAPDH 0 0 569 644 1 2
    SIRT2 GCSH 0 0 0 196 1 1
    SIRT2 GZMM 0 0 94 170 1 1
    SIRT2 ZNFX1 0 0 0 174 1 1
    SIRT2 HIST2H2AC 0 0 562 585 1 1
    SIRT2 KDM4E 0 0 142 155 1 1
    SIRT2 CREB1 0 0 469 469 1 1
    SIRT2 PIEZO2 0 0 217 217 1 1
    SIRT2 PFKFB3 0 0 184 215 1 1
    SIRT2 HCAR2 0 0 283 282 1 1
    SIRT2 ACO2 0 0 235 337 1 1
    SIRT2 BIVM-ERCC5 0 0 0 168 1 1
    SIRT2 NFE2 0 0 150 181 1 1
    SIRT2 SDHB 0 0 150 168 1 1
    SIRT2 ESRRA 0 0 391 414 1 1
    SIRT2 BCL11B 0 0 125 162 1 1
    SIRT2 CKAP5 0 0 46 182 1 1
    SIRT2 GCKR 270 0 218 409 1 1
    SIRT2 TERF2 0 0 210 219 1 1
    SIRT2 FOXD4L1 0 0 0 166 1 1
    SIRT2 PPCS 0 0 74 330 1 1
    SIRT2 CREBBP 0 0 451 536 1 1
    SIRT2 HSF1 0 0 155 211 1 1
    SIRT2 REPIN1 0 0 193 207 1 1
    SIRT2 FTO 0 0 123 183 1 1
    SIRT2 RRN3 0 0 181 210 1 1
    SIRT2 SULT2A1 0 0 161 161 1 1
    SIRT2 SLC25A6 0 0 134 235 1 1
    SIRT2 POLR2A 0 0 102 250 1 1
    SIRT2 NAT10 0 0 172 438 1 1
    SIRT2 SUV420H1 0 0 202 235 1 1
    SIRT2 MTOR 0 0 601 632 1 2
    SIRT2 RAD51 76 0 365 443 1 1
    SIRT2 FLAD1 0 0 161 181 1 1
    SIRT2 AIM1 0 0 661 661 1 1
    SIRT2 JARID2 0 0 150 217 1 1
    SIRT2 CXCR4 0 0 153 152 1 2
    SIRT2 HIST1H4F 0 0 686 745 1 1
    SIRT2 ANKRD52 0 0 0 192 1 1
    SIRT2 KAT6B 0 0 296 433 1 1
    SIRT2 ELAVL3 0 0 158 179 1 1
    SIRT2 STAT1 0 0 234 234 1 1
    SIRT2 ENDOG 0 0 204 221 1 1
    SIRT2 ART1 0 0 136 151 1 1
    SIRT2 THRA 0 0 102 158 1 1
    SIRT2 PIK3C3 0 0 211 504 1 2
    SIRT2 CXXC1 0 0 142 200 1 1
    SIRT2 GSPT1 0 0 107 211 1 1
    SIRT2 TBL1XR1 0 0 103 169 1 1
    SIRT2 MOG 0 0 120 182 1 1
    SIRT2 EPHX2 0 0 55 235 1 1
    SIRT2 CTRL 0 0 150 180 1 1
    SIRT2 TCF20 0 0 74 194 1 1
    SIRT2 NPAS2 0 0 242 276 1 1
    SIRT2 H2BFWT 0 0 0 170 1 1
    SIRT2 CHD1L 0 0 136 184 1 1
    SIRT2 CPS1 0 0 370 391 1 1
    SIRT2 CLC 0 0 165 165 1 1
    SIRT2 CXCL8 0 0 298 298 1 1
    SIRT2 POLR2C 0 0 123 164 1 1
    SIRT2 ATXN1 0 0 143 201 1 1
    SIRT2 UQCRC2 0 0 134 266 1 1
    SIRT2 NEDD4 0 0 189 206 1 2
    SIRT2 NR1H3 0 0 145 219 1 1
    SIRT2 C9orf78 0 0 96 153 1 1
    SIRT2 BAZ1A 0 0 90 232 1 1
    SIRT2 ORC1 0 0 97 310 1 1
    SIRT2 HRAS 0 0 261 283 1 1
    SIRT2 CTNNB1 0 0 762 767 1 1
    SIRT2 EGR1 0 0 181 195 1 1
    SIRT2 MFN2 0 0 325 368 1 2
    SIRT2 APP 0 0 405 406 1 1
    SIRT2 RAD9A 0 0 244 262 1 1
    SIRT2 PCYT2 0 0 69 153 1 1
    SIRT2 MYBL1 0 0 295 346 1 1
    SIRT2 BRD4 0 0 325 430 1 1
    SIRT2 NR4A1 0 0 166 165 1 1
    SIRT2 CISD2 0 0 384 397 1 2
    SIRT2 GPR156 0 0 73 194 1 1
    SIRT2 HSPA12B 0 0 0 164 1 1
    SIRT2 GHRL 0 0 233 232 1 1
    SIRT2 JAK2 0 0 161 161 1 1
    SIRT2 HDAC6 486 0 962 986 1 2
    SIRT2 APAF1 0 0 231 256 1 1
    SIRT2 EIF2AK4 0 0 233 236 1 1
    SIRT2 TBRG1 0 0 0 165 1 1
    SIRT2 GDNF 0 0 195 195 1 1
    SIRT2 PHF7 0 0 0 165 1 1
    SIRT2 NCOA1 0 0 108 205 1 1
    SIRT2 CENPA 0 0 203 323 1 1
    SIRT2 UBR5 0 0 107 220 1 1
    SIRT2 NDUFS1 0 0 193 321 1 1
    SIRT2 PMPCA 0 0 0 167 1 1
    SIRT2 GCLM 0 0 124 158 1 1
    SIRT2 HIST1H2BI 0 0 0 170 1 1
    SIRT2 TCEA1 0 0 171 171 1 1
    SIRT2 MYH6 0 0 142 155 1 1
    SIRT2 SLC2A1 0 0 359 378 1 1
    SIRT2 NEDD8 0 0 90 190 1 1
    SIRT2 OARD1 0 0 369 369 1 1
    SIRT2 EGFR 0 0 293 300 1 1
    SIRT2 CFLAR 0 0 150 208 1 1
    SIRT2 OPLAH 0 0 0 417 1 1
    SIRT2 HTT 0 0 506 528 1 1
    SIRT2 TP53 0 0 707 712 1 2
    SIRT2 MDM2 270 0 405 547 1 1
    SIRT2 PRPSAP1 0 0 0 151 1 1
    SIRT2 MAOA 0 0 173 241 1 1
    SIRT2 ADAT2 0 0 72 510 1 1
    SIRT2 HDAC2 0 0 739 840 1 1
    SIRT2 TNS3 0 0 0 159 1 1
    SIRT2 MAP1A 0 0 171 181 1 1
    SIRT2 PDCD2 0 0 306 322 1 1
    SIRT2 NCOR2 0 0 323 458 1 1
    SIRT2 CUL2 0 0 94 202 1 1
    SIRT2 BST1 0 650 517 823 1 1
    SIRT2 DUSP4 0 0 45 159 1 1
    SIRT2 HIST1H2BH 0 0 0 170 1 1
    SIRT2 ZNF501 0 0 189 203 1 1
    SIRT2 ACTA1 0 0 112 183 1 1
    SIRT2 SLC2A3 0 0 153 178 1 1
    SIRT2 MDC1 0 0 128 264 1 1
    SIRT2 MTA1 0 0 151 150 1 1
    SIRT2 STK11 0 0 468 485 1 2
    SIRT2 BRCA1 0 0 391 390 1 1
    SIRT2 BOLA2 0 0 0 152 1 1
    SIRT2 OPA1 0 0 141 311 1 1
    SIRT2 TOP2A 0 0 118 166 1 1
    SIRT2 RB1CC1 0 0 167 186 1 2
    SIRT2 CDC5L 0 0 96 162 1 1
    SIRT2 NAP1L2 0 0 0 192 1 1
    SIRT2 MTMR2 0 0 57 155 1 1
    SIRT2 PPP1R1B 0 0 170 169 1 1
    SIRT2 FOXR2 0 0 0 166 1 1
    SIRT2 PCK1 114 0 424 472 1 1
    SIRT2 PPARGC1A 0 0 710 730 1 1
    SIRT2 CDC14A 0 0 974 978 1 1
    SIRT2 BLOC1S1 0 0 299 303 1 1
    SIRT2 ADAM10 0 0 252 252 1 1
    SIRT2 CBLB 270 0 0 287 1 1
    SIRT2 DGAT1 0 0 119 207 1 1
    SIRT2 PPRC1 0 0 103 223 1 1
    SIRT2 FOXN3 0 0 0 166 1 1
    SIRT2 CLOCK 0 0 467 491 1 2
    SIRT2 CBX5 0 0 181 308 1 1
    SIRT2 ILK 0 0 85 155 1 1
    SIRT2 PARK2 0 0 342 346 1 1
    SIRT2 NR0B2 0 0 144 177 1 1
    SIRT2 TOP1 0 0 323 368 1 1
    SIRT2 CETN3 0 0 214 245 1 1
    SIRT2 UBXN7 0 0 0 210 1 1
    SIRT2 MICU1 0 0 95 151 1 1
    SIRT2 HNF4G 0 0 0 157 1 1
    SIRT2 ENSG00000261832 0 0 107 182 1 1
    SIRT2 RICTOR 0 0 241 273 1 2
    SIRT2 VASN 0 0 45 160 1 1
    SIRT2 G6PC 0 0 325 329 1 1
    SIRT2 GPX7 0 0 72 158 1 1
    SIRT2 GNAQ 0 0 75 165 1 1
    SIRT2 KCNS1 0 0 0 158 1 1
    SIRT2 LMNB1 0 0 270 295 1 1
    SIRT2 C17orf80 0 0 181 195 1 1
    SIRT2 MYOCD 0 0 161 161 1 1
    SIRT2 SMAD7 0 0 212 289 1 1
    SIRT2 SENP3 0 0 181 229 1 1
    SIRT2 PDK4 0 0 213 233 1 1
    SIRT2 H2AFY 0 0 417 560 1 1
    SIRT2 ESR1 0 0 360 384 1 1
    SIRT2 MSH2 0 0 138 201 1 1
    SIRT2 NSD1 0 0 120 234 1 1
    SIRT2 FOXN2 0 0 0 166 1 1
    SIRT2 CACUL1 0 0 0 155 1 1
    SIRT2 KLF11 0 0 108 178 1 1
    SIRT2 PAPSS2 0 0 155 184 1 1
    SIRT2 PRKD1 0 0 233 232 1 1
    SIRT2 HIST2H3A 0 0 43 187 1 1
    SIRT2 SYP 0 0 123 155 1 1
    SIRT2 BRD8 0 0 55 203 1 1
    SIRT2 SMEK1 0 0 283 312 1 1
    SIRT2 YAP1 0 0 134 243 1 1
    SIRT2 TTF1 0 0 96 162 1 1
    SIRT2 SLC6A3 0 0 95 151 1 1
    SIRT2 TSG101 0 0 61 266 1 2
    SIRT2 PPFIBP1 0 0 460 460 1 1
    SIRT2 CDC45 0 0 145 246 1 1
    SIRT2 EXOG 0 0 134 152 1 1
    SIRT2 MCM2 0 0 150 198 1 1
    SIRT2 TET2 0 0 243 249 1 1
    SIRT2 TERT 0 0 325 381 1 1
    SIRT2 HHAT 0 0 150 193 1 1
    SIRT2 MAP1LC3B 0 0 216 281 1 2
    SIRT2 MATN3 0 0 247 259 1 1
    SIRT2 SARS 388 0 161 486 1 1
    SIRT2 PRKCA 0 0 129 155 1 1
    SIRT2 HIST1H2BE 0 0 0 170 1 1
    SIRT2 ATP5G1 0 0 70 222 1 1
    SIRT2 CAMK2A 0 0 101 188 1 2
    SIRT2 RAD52 0 0 372 451 1 1
    SIRT2 ULK1 0 0 323 336 1 2
    SIRT2 SETD2 0 0 344 445 1 1
    SIRT2 RARS 0 0 193 227 1 1
    SIRT2 MT-CYB 0 0 164 163 1 1
    SIRT2 FN1 0 0 216 216 1 1
    SIRT2 MT-CO1 0 0 161 161 1 1
    SIRT2 TBP 0 0 260 281 1 1
    SIRT2 SETDB2 0 0 132 245 1 1
    SIRT2 MPST 0 0 84 157 1 1
    SIRT2 MMP13 0 0 172 173 1 1
    SIRT2 CECR2 0 0 54 202 1 1
    SIRT2 IGF2 0 0 218 218 1 1
    SIRT2 SOX10 0 0 150 218 1 1
    SIRT2 DENND5B 0 0 0 189 1 1
    SIRT2 MDM4 0 0 181 181 1 1
    SIRT2 GOT2 0 0 150 207 1 1
    SIRT2 OGT 0 0 142 158 1 1
    SIRT2 FOSB 0 0 180 244 1 1
    SIRT2 FOXD4L6 0 0 0 166 1 1
    SIRT2 DMD 130 0 90 174 1 1
    SIRT2 NR1H4 0 0 235 264 1 1
    SIRT2 PRPS1 0 0 56 164 1 1
    SIRT2 DYRK1B 0 0 0 189 1 1
    SIRT2 DLG4 0 0 129 171 1 1
    SIRT2 IL10 0 0 296 296 1 1
    SIRT2 SNAI1 274 0 233 419 1 1
    SIRT2 KDM4C 0 0 155 168 1 1
    SIRT2 CLIP3 0 0 104 280 1 1
    SIRT2 TAF1L 0 0 323 357 1 1
    SIRT2 TNPO1 0 0 81 221 1 1
    SIRT2 FLT3 0 0 135 154 1 1
    SIRT2 NPM1 0 0 166 191 1 1
    SIRT2 NUTF2 0 0 82 178 1 1
    SIRT2 MTA2 0 0 161 161 1 1
    SIRT2 SLC2A14 0 0 165 190 1 1
    SIRT2 SLC9C2 0 0 0 164 1 1
    SIRT2 FOXL1 0 0 0 166 1 1
    SIRT2 DUSP28 0 0 0 156 1 1
    SIRT2 DNAAF2 0 0 160 179 1 1
    SIRT2 BHLHE41 0 0 67 169 1 1
    SIRT2 NUDT1 0 0 135 201 1 1
    SIRT2 GAPDHS 0 0 0 206 1 1
    SIRT2 AASDHPPT 0 0 181 264 1 1
    SIRT2 MMP11 0 0 599 599 1 1
    SIRT2 NME8 0 0 0 190 1 1
    SIRT2 RECQL5 0 0 46 205 1 1
    SIRT2 PAPOLA 270 0 0 303 1 1
    SIRT2 TERF1 0 0 265 273 1 1
    SIRT2 AGO1 0 0 123 183 1 1
    SIRT2 PPIL4 0 0 0 158 1 1
    SIRT2 AMBRA1 0 0 122 232 1 2
    SIRT2 RARB 0 0 185 216 1 1
    SIRT2 H2BFS 0 0 0 170 1 1
    SIRT2 HIST1H3B 0 0 69 209 1 1
    SIRT2 LDHA 0 0 335 354 1 1
    SIRT2 COMMD3-BMI1 0 0 193 210 1 1
    SIRT2 PNMAL2 0 0 0 235 1 1
    SIRT2 ACY1 0 0 96 150 1 1
    SIRT2 CCNA1 0 0 45 158 1 1
    SIRT2 KAT5 0 0 520 613 1 2
    SIRT2 HIST1H4K 0 0 686 745 1 1
    SIRT2 RCOR2 0 0 0 207 1 1
    SIRT2 CHFR 0 0 154 153 1 1
    SIRT2 BUB3 0 0 123 158 1 1
    SIRT2 CYBB 0 0 212 212 1 1
    SIRT2 RAD21 0 0 217 309 1 1
    SIRT2 SEPT7 0 0 363 378 1 1
    SIRT2 HDAC11 0 0 805 851 1 1
    SIRT2 HIST1H2BG 0 0 0 170 1 1
    SIRT2 SMARCA1 0 0 374 409 1 1
    SIRT2 ACE 0 0 218 218 1 1
    SIRT2 POLR3A 0 0 0 200 1 1
    SIRT2 TNFRSF10B 0 0 235 235 1 1
    SIRT2 REN 0 0 260 298 1 1
    SIRT2 TUB 0 0 122 200 1 1
    SIRT2 ENPP1 0 650 81 672 1 1
    SIRT2 MLLT3 0 0 149 190 1 1
    SIRT2 HADH 0 0 155 175 1 1
    SIRT2 CASP3 0 0 450 450 1 2
    SIRT2 ATAT1 0 0 653 672 1 1
    SIRT2 PTGS2 0 0 294 294 1 1
    SIRT2 HCRT 0 0 195 195 1 1
    SIRT2 EGLN1 0 0 179 247 1 1
    SIRT2 REL 0 0 167 167 1 1
    SIRT2 NLRP3 0 0 341 352 1 2
    SIRT2 ATXN7L1 0 0 0 166 1 1
    SIRT2 BRCA2 0 0 159 178 1 1
    SIRT2 HDAC9 0 0 661 767 1 1
    SIRT2 PARG 0 0 458 473 1 1
    SIRT2 HPSE2 0 0 234 234 1 1
    SIRT2 BDH1 0 0 164 174 1 1
    SIRT2 ERCC5 0 0 55 180 1 1
    SIRT2 TXNRD2 0 0 144 161 1 1
    SIRT2 RIPK1 0 0 302 302 1 1
    SIRT2 ACO1 0 0 113 152 1 1
    SIRT2 MORF4L1 0 0 206 222 1 1
    SIRT2 BANF1 0 0 181 181 1 1
    SIRT2 TXNRD1 0 0 165 217 1 1
    SIRT2 CEBPB 0 0 283 300 1 1
    SIRT2 DUSP2 0 0 0 156 1 1
    SIRT2 UNC119 0 0 97 369 1 1
    SIRT2 ZFP90 0 0 53 450 1 1
    SIRT2 NUDT9 0 0 207 207 1 1
    SIRT2 CDKN2A 0 0 427 462 1 2
    SIRT2 PPP6C 0 0 113 182 1 1
    SIRT2 S100B 0 0 158 182 1 1
    SIRT2 GSK3B 0 0 261 261 1 2
    SIRT2 TTR 0 0 447 447 1 2
    SIRT2 GPX8 0 0 95 179 1 1
    SIRT2 KRAS 0 0 260 274 1 1
    SIRT2 FOXD1 0 0 0 166 1 1
    SIRT2 JMJD6 0 0 211 211 1 1
    SIRT2 PHF23 0 0 0 166 1 1
    SIRT2 FOXK1 0 0 46 170 1 1
    SIRT2 ASCL1 0 0 145 159 1 1
    SIRT2 MLST8 0 0 247 268 1 2
    SIRT2 HIST1H3E 0 0 160 286 1 1
    SIRT2 KDM2B 0 0 193 318 1 1
    SIRT2 PON1 0 0 159 158 1 1
    SIRT2 STAT5A 0 0 156 155 1 1
    SIRT2 EDC3 0 0 107 163 1 1
    SIRT2 FOXN1 0 0 0 166 1 1
    SIRT2 QPRT 0 0 369 436 1 1
    SIRT2 DEPTOR 0 0 158 157 1 1
    SIRT2 TNIP1 0 0 0 173 1 1
    SIRT2 TRDMT1 0 0 218 249 1 1
    SIRT2 KDM6B 0 0 323 410 1 1
    SIRT2 FASLG 0 0 193 193 1 1
    SIRT2 DUSP27 0 0 0 156 1 1
    SIRT2 ANKRD32 0 0 0 180 1 1
    SIRT2 WDR59 0 0 60 172 1 1
    SIRT2 FOXC1 0 0 0 166 1 1
    SIRT2 RBBP8 0 0 298 298 1 1
    SIRT2 LPIN1 0 0 155 285 1 2
    SIRT2 GABBR1 0 0 60 158 1 1
    SIRT2 CAPG 0 0 0 166 1 1
    SIRT2 IPO7 0 0 96 203 1 1
    SIRT2 DUSP1 0 0 445 523 1 1
    SIRT2 ACADL 0 0 161 161 1 1
    SIRT2 NCAPD2 0 0 55 293 1 1
    SIRT2 CHAF1A 0 0 120 195 1 1
    SIRT2 ELAVL4 0 0 180 195 1 1
    SIRT2 MLH1 0 0 164 227 1 1
    SIRT2 ATXN3 0 0 159 169 1 1
    SIRT2 HIST1H4G 0 0 0 194 1 1
    SIRT2 MACROD1 0 0 408 542 1 1
    SIRT2 MED7 0 0 67 178 1 1
    SIRT2 NAP1L4 0 0 0 204 1 1
    SIRT2 MAPT 270 0 364 533 1 2
    SIRT2 BECN1 0 0 391 417 1 2
    SIRT2 SMARCD3 0 0 95 165 1 1
    SIRT2 ZC3HAV1 0 0 218 218 1 1
    SIRT2 FBXL19 0 0 0 246 1 1
    SIRT2 DNAJB6 270 0 112 336 1 1
    SIRT2 IL2 0 0 180 179 1 1
    SIRT2 ASH2L 0 0 134 153 1 1
    SIRT2 GYS1 211 0 54 221 1 1
    SIRT2 HIST1H2BB 0 0 45 173 1 1
    SIRT2 PHF2 0 0 45 172 1 1
    SIRT2 DUSP23 0 0 0 156 1 1
    SIRT2 UBR4 0 0 126 213 1 1
    SIRT2 SP140 213 0 0 229 1 1
    SIRT2 AKT1 0 0 678 695 1 2
    SIRT2 PPARG 0 0 559 576 1 1
    SIRT2 SETX 0 0 113 172 1 1
    SIRT2 ERMN 0 0 159 216 1 1
    SIRT2 CD4 0 0 241 240 1 1
    SIRT2 HIST1H2BA 0 0 61 187 1 1
    SIRT2 HOXA10 213 900 759 979 1 1
    SIRT2 NUDT12 196 900 68 927 1 1
    SIRT2 PRDM16 0 0 172 186 1 1
    SIRT2 SGK3 0 0 84 195 1 1
    SIRT2 FOXA1 0 0 95 238 1 1
    SIRT2 IKBKB 0 0 182 181 1 1
    SIRT2 LETM1 0 0 95 171 1 1
    SIRT2 ATF6 0 0 181 181 1 2
    SIRT2 KLF4 0 0 213 226 1 1
    SIRT2 BRDT 0 0 283 395 1 1
    SIRT2 TAF3 0 0 0 194 1 1
    SIRT2 SLC36A1 0 0 0 252 1 1
    SIRT2 HUS1 0 0 120 226 1 1
    SIRT2 PPP2R4 0 0 234 234 1 1
    SIRT2 XIAP 0 0 195 266 1 1
    SIRT2 RUNX2 0 0 227 226 1 1
    SIRT2 RAI1 0 0 0 165 1 1
    SIRT2 DISC1 0 0 54 158 1 1
    SIRT2 ATOH1 0 0 48 193 1 1
    SIRT2 SIRT4 0 0 752 465 1 1
    SIRT2 FOXE1 0 0 0 166 1 1
    SIRT2 SUPT16H 0 0 193 237 1 1
    SIRT2 CETN1 0 0 193 224 1 1
    SIRT2 HIST3H2BB 0 0 0 170 1 1
    SIRT2 SMC4 0 0 142 273 1 1
    SIRT2 WDHD1 0 0 212 353 1 1
    SIRT2 ING5 0 0 91 216 1 1
    SIRT2 GFPT2 0 0 73 160 1 1
    SIRT2 VLDLR 0 0 63 159 1 1
    SIRT2 BBC3 0 0 161 161 1 1
    SIRT2 FOXD4L3 0 0 0 166 1 1
    SIRT2 ARG2 0 0 160 171 1 1
    SIRT2 ERBB2 0 0 245 252 1 2
    SIRT2 FOXF2 0 0 0 166 1 1
    SIRT2 PRDX3 0 0 213 226 1 1
    SIRT2 CDYL2 0 0 0 189 1 1
    SIRT2 ENSG00000274276 0 0 155 154 1 1
    SIRT2 C19orf44 0 0 134 221 1 1
    SIRT2 HIST1H3G 0 0 70 210 1 1
    SIRT2 YWHAB 0 0 828 852 1 1
    SIRT2 RPP25 0 0 155 189 1 1
    SIRT2 KDM4B 0 0 193 205 1 1
    SIRT2 DUSP19 0 0 0 156 1 1
    SIRT2 KDM6A 0 0 233 331 1 1
    SIRT2 MCU 0 0 171 171 1 1
    SIRT2 DENND5A 0 0 0 189 1 1
    SIRT2 G2E3 0 0 0 165 1 1
    SIRT2 ATAD5 0 0 108 154 1 1
    SIRT2 SARS2 0 0 143 172 1 1
    SIRT2 SMARCC1 0 0 140 175 1 1
    SIRT2 SLK 0 0 282 282 1 1
    SIRT2 HSPA12A 0 0 0 164 1 1
    SIRT2 EED 0 0 162 285 1 1
    SIRT2 SRC 0 0 288 288 1 1
    SIRT2 ATP5J2 0 0 66 227 1 1
    SIRT2 SCD 0 0 212 212 1 1
    SIRT2 VHL 0 0 218 231 1 1
    SIRT2 COASY 0 0 142 186 1 1
    SIRT2 SLC25A5 0 0 155 254 1 1
    SIRT2 ING2 0 0 120 241 1 1
    SIRT2 PAPD5 0 0 0 161 1 1
    SIRT2 ACLY 270 0 458 618 1 1
    SIRT2 EIF2AK3 0 0 251 250 1 2
    SIRT2 FOXJ2 0 0 0 170 1 1
    SIRT2 DNMT3L 0 0 211 211 1 1
    SIRT2 TCHP 0 0 392 392 1 1
    SIRT2 GLRX 0 0 204 221 1 1
    SIRT2 ATP5H 0 0 74 237 1 1
    SIRT2 KDM5A 0 0 211 273 1 1
    SIRT2 ING4 0 0 0 173 1 1
    SIRT2 HMOX1 0 0 395 419 1 2
    SIRT2 EIF2S1 0 0 172 171 1 2
    SIRT2 LCOR 0 0 61 206 1 1
    SIRT2 ERAL1 0 0 181 182 1 1
    SIRT2 OXR1 0 0 113 163 1 1
    SIRT2 NFATC2 0 0 439 439 1 1
    SIRT2 TBPL2 0 0 131 156 1 1
    SIRT2 TSC2 0 0 287 302 1 2
    SIRT2 RBX1 0 0 112 158 1 1
    SIRT2 RBP1 270 0 77 297 1 1
    SIRT2 TRRAP 0 0 181 245 1 1
    SIRT2 POLR2B 0 0 112 157 1 1
    SIRT2 OXSM 0 0 74 199 1 1
    SIRT2 BNIP3L 0 0 228 234 1 2
    SIRT2 PTPDC1 0 0 0 156 1 1
    SIRT2 NARFL 0 0 93 189 1 1
    SIRT2 CTCF 0 0 203 217 1 1
    SIRT2 GTF2B 0 0 116 193 1 1
    SIRT2 CDKN1B 0 0 263 330 1 2
    SIRT2 DUSP13 0 0 0 156 1 1
    SIRT2 ATP5G2 0 0 61 165 1 1
    SIRT2 RB1 0 0 181 205 1 2
    SIRT2 DNAJB2 0 0 0 152 1 1
    SIRT2 ANKRD50 0 0 0 192 1 1
    SIRT2 PLEKHG3 0 0 61 155 1 1
    SIRT2 TPRKB 0 0 125 158 1 1
    SIRT2 BLM 0 0 47 206 1 1
    SIRT2 RPA1 0 0 141 299 1 1
    SIRT2 GPAM 299 0 90 352 1 1
    SIRT2 SMAD6 0 0 67 158 1 1
    SIRT2 FOXA2 0 0 116 255 1 1
    SIRT2 PITPNA 0 0 0 254 1 1
    SIRT2 MYB 0 0 103 168 1 1
    SIRT2 DDIT4 0 0 143 173 1 1
    SIRT2 TOB2 0 0 0 192 1 1
    SIRT2 NFASC 0 0 150 302 1 1
    SIRT2 HPRT1 0 0 143 156 1 1
    SIRT2 SSH3 0 0 0 156 1 1
    SIRT2 AARS 0 0 122 178 1 1
    SIRT2 SMYD5 0 0 0 165 1 1
    SIRT2 MCM7 0 0 265 294 1 1
    SIRT2 POU5F1 0 0 218 234 1 1
    SIRT2 ACAT1 0 0 158 185 1 1
    SIRT2 HIST1H3F 0 0 70 210 1 1
    SIRT2 GRIA1 0 0 160 179 1 1
    SIRT2 HELZ2 0 0 0 269 1 1
    SIRT2 AVIL 0 0 0 207 1 1
    SIRT2 GSTT2B 129 0 0 162 1 1
    SIRT2 DUSP6 0 0 55 168 1 1
    SIRT2 CAT 0 0 560 589 1 1
    SIRT2 NCOR1 0 0 467 573 1 1
    SIRT2 CDK1 0 0 325 355 1 1
    SIRT2 DOT1L 0 0 518 605 1 1
    SIRT2 PGR 0 0 158 190 1 1
    SIRT2 HIST1H4B 0 0 686 745 1 1
    SIRT2 CRBN 0 0 395 408 1 1
    SIRT2 SERPINE1 0 0 212 212 1 1
    SIRT2 AHR 0 0 218 218 1 1
    SIRT2 RPS6KB1 0 0 395 468 1 2
    SIRT2 AGTR1 0 0 180 179 1 1
    SIRT2 HSPA9 0 0 170 367 1 1
    SIRT2 CBL 270 0 71 309 1 1
    SIRT2 IRS1 0 0 321 337 1 1
    SIRT2 SGK1 0 0 212 307 1 1
    SIRT2 BEX4 0 0 112 173 1 1
    SIRT2 LOX 0 0 172 171 1 1
    SIRT2 FOXD4 0 0 0 166 1 1
    SIRT2 PAXIP1 0 0 67 191 1 1
    SIRT2 ATR 0 0 436 481 1 1
    SIRT2 FOXC2 0 0 90 208 1 1
    SIRT2 SMYD1 0 0 102 218 1 1
    SIRT2 ABCG2 0 0 108 156 1 1
    SIRT2 DUSP18 0 0 0 156 1 1
    SIRT2 HDAC7 0 0 611 732 1 1
    SIRT2 ZNF569 0 0 204 218 1 1
    SIRT2 PC 0 0 204 251 1 1
    SIRT2 ALDH2 0 0 219 276 1 1
    SIRT2 SREBF2 0 0 296 322 1 1
    SIRT2 SBNO1 0 0 0 212 1 1
    SIRT2 ATG4B 0 0 134 190 1 2
    SIRT2 PARP15 0 0 219 252 1 1
    SIRT2 HIST1H2BF 0 0 0 170 1 1
    SIRT2 GSTP1 0 0 155 154 1 1
    SIRT2 GCG 0 0 325 325 1 1
    SIRT2 CDC7 0 0 117 224 1 1
    SIRT2 AGT 0 0 61 172 1 1
    SIRT2 CCND2 0 0 108 153 1 1
    SIRT2 NUDT5 0 0 263 314 1 1
    SIRT2 CSNK2A1 0 0 136 190 1 1
    SIRT2 PRLR 0 0 0 188 1 1
    SIRT2 SMC5 0 0 143 237 1 1
    SIRT2 TXNIP 0 0 283 309 1 1
    SIRT2 TOMM5 0 0 0 188 1 1
    SIRT2 REST 0 0 204 218 1 1
    SIRT2 GLRX2 0 0 155 173 1 1
    SIRT2 DRAM1 0 0 164 163 1 2
    SIRT2 ZMPSTE24 0 0 234 323 1 1
    SIRT2 RETN 0 0 173 173 1 1
    SIRT2 PGAM1 0 0 274 305 1 1
    SIRT2 ATF3 0 0 124 192 1 1
    SIRT2 ATOX1 0 0 112 167 1 1
    SIRT2 EZH1 0 0 123 237 1 1
    SIRT2 SLC38A3 0 0 204 208 1 1
    SIRT2 ARNTL 0 0 460 500 1 1
    SIRT2 ESCO1 0 0 240 262 1 1
    SIRT2 AGK 0 0 392 405 1 1
    SIRT2 PARP3 0 0 341 358 1 1
    SIRT2 FOXL2 0 0 0 166 1 1
    SIRT2 LARS 0 0 112 159 1 1
    SIRT2 NFYC 0 0 0 164 1 1
    SIRT2 UQCRC1 0 0 68 201 1 1
    SIRT2 KYNU 0 0 112 167 1 1
    SIRT2 LINS 0 0 0 162 1 1
    SIRT2 RNF4 0 0 163 177 1 1
    SIRT2 TNF 0 0 457 464 1 1
    SIRT2 STK32C 0 0 0 157 1 1
    SIRT2 DNAJC6 0 0 0 171 1 1
    SIRT2 FBXO18 0 0 0 178 1 1
    SIRT2 VDR 0 0 145 177 1 1
    SIRT2 TMEM167A 0 0 0 345 1 1
    SIRT2 KDM3A 0 0 290 290 1 1
    SIRT2 LPIN2 0 0 52 177 1 1
    SIRT2 MMP3 0 0 157 158 1 1
    SIRT2 PIAS2 0 0 161 211 1 1
    SIRT2 TDG 0 0 398 416 1 1
    SIRT2 VAPB 0 0 0 179 1 1
    SIRT2 NT5E 0 0 140 150 1 1
    SIRT2 GFER 0 0 74 195 1 1
    SIRT2 SIN3A 0 0 273 324 1 1
    SIRT2 MEF2C 0 0 138 179 1 1
    SIRT2 ALDH18A1 0 0 0 184 1 1
    SIRT2 ALDH7A1 0 0 166 179 1 1
    SIRT2 WIPI2 0 0 73 201 1 2
    SIRT2 RCAN1 0 0 113 203 1 2
    SIRT2 FIS1 0 0 287 310 1 2
    SIRT2 RBBP7 0 0 212 256 1 1
    SIRT2 ATXN7 0 0 180 286 1 1
    SIRT2 MLYCD 0 0 377 391 1 1
    SIRT2 TTL 0 0 211 224 1 1
    SIRT2 EEF2 0 0 156 184 1 1
    SIRT2 PAPD4 0 0 72 175 1 1
    SIRT2 FMR1 0 0 150 173 1 1
    SIRT2 MDH1 0 0 451 468 1 1
    SIRT2 UNC119B 0 0 0 250 1 1
    SIRT2 SETD7 0 0 503 567 1 1
    SIRT2 PRKAB2 0 0 70 203 1 1
    SIRT2 SMARCA5 0 360 392 617 1 1
    SIRT2 AKR1B1 0 0 211 220 1 1
    SIRT2 FASN 0 0 232 231 1 1
    SIRT2 POMC 0 0 253 252 1 1
    SIRT2 NMRK2 0 0 260 274 1 1
    SIRT2 CASP9 0 0 242 241 1 1
    SIRT2 NANOG 0 0 209 209 1 1
    SIRT2 HK1 0 0 232 264 1 1
    SIRT2 MAPK9 0 0 141 275 1 2
    SIRT2 CHEK2 0 0 343 468 1 1
    SIRT2 OGG1 0 0 241 303 1 1
    SIRT2 CWC27 0 0 0 164 1 1
    SIRT2 PLK2 0 0 81 156 1 1
    SIRT2 BPTF 0 0 107 346 1 1
    SIRT2 RPTOR 0 0 323 405 1 2
    SIRT2 MRPS5 0 0 207 359 1 1
    SIRT2 PIF1 0 0 213 301 1 1
    SIRT2 RAD17 0 0 194 214 1 1
    SIRT2 HIF1AN 0 0 166 175 1 1
    SIRT2 TRIP13 0 0 281 315 1 1
    SIRT2 PER3 0 0 150 191 1 1
    SIRT2 SCMH1 0 0 48 202 1 1
    SIRT2 ACAD10 0 0 74 302 1 1
    SIRT2 RPS6KB2 0 0 81 192 1 2
    SIRT2 CTGF 0 0 155 154 1 1
    SIRT2 HNMT 0 0 391 390 1 1
    SIRT2 GRINA 0 0 0 159 1 1
    SIRT2 HES5 0 0 134 158 1 1
    SIRT2 SMARCB1 0 0 143 156 1 1
    SIRT2 H2AFZ 0 0 391 423 1 1
    SIRT2 CPT1B 0 0 149 154 1 1
    SIRT2 NR3C1 0 0 283 328 1 1
    SIRT2 GLUD1 0 0 357 397 1 1
    SIRT2 FKBP1A 0 0 202 211 1 2
    SIRT2 TNS1 0 0 103 210 1 1
    SIRT2 SCIN 0 0 0 650 1 1
    SIRT2 HSPA6 0 0 0 164 1 1
    SIRT2 SURF1 0 0 150 169 1 1
    SIRT2 HIST2H3PS2 0 0 683 730 1 1
    SIRT2 FOXI1 0 0 0 166 1 1
    SIRT2 FOXP1 0 0 81 200 1 1
    SIRT2 RUVBL1 0 0 158 177 1 1
    SIRT2 TMEM167B 0 0 0 256 1 1
    SIRT2 ADIPOQ 0 0 404 404 1 1
    SIRT2 SKP2 270 0 259 435 1 1
    SIRT2 GCLC 0 0 125 152 1 1
    SIRT2 PRKAB1 0 0 73 198 1 2
    SIRT2 AURKB 0 0 218 322 1 1
    SIRT2 MLLT11 0 0 0 151 1 1
    SIRT2 ARG1 0 0 155 166 1 1
    SIRT2 ZNF763 0 0 188 202 1 1
    SIRT2 MLXIPL 0 0 245 244 1 1
    SIRT2 BMP7 0 0 134 320 1 1
    SIRT2 YWHAG 0 0 95 223 1 1
    SIRT2 HYOU1 0 0 0 164 1 1
    SIRT2 HIST1H4E 0 0 686 745 1 1
    SIRT2 RAB3GAP2 313 0 0 328 1 1
    SIRT2 HMGCS2 0 0 391 402 1 1
    SIRT2 KMT2B 0 0 171 278 1 1
    SIRT2 CDK6 0 0 193 228 1 1
    SIRT2 HDAC8 0 0 759 834 1 1
    SIRT2 TTLL1 0 0 113 175 1 1
    SIRT2 IL1A 0 0 205 205 1 1
    SIRT2 TFPI 0 0 189 189 1 1
    SIRT2 AK7 0 0 324 323 1 1
    SIRT2 H2AFX 0 0 304 340 1 1
    SIRT2 CUL5 0 0 43 157 1 1
    SIRT2 DCTN1 0 0 97 247 1 1
    SIRT2 ABCA1 0 0 181 225 1 1
    SIRT2 POLG 0 0 173 238 1 1
    SIRT2 SUZ12 0 0 150 171 1 1
    SIRT2 DEGS1 221 0 0 221 1 1
    SIRT2 GSPT2 0 0 0 153 1 1
    SIRT2 DPP4 0 0 134 169 1 1
    SIRT2 FOXI3 0 0 0 166 1 1
    SIRT2 STK32A 0 0 0 157 1 1
    SIRT2 BOLA2B 0 0 0 152 1 1
    SIRT2 NFIL3 0 0 125 152 1 1
    SIRT2 LGALS4 0 0 372 372 1 1
    SIRT2 ZNF436 0 0 187 201 1 1
    SIRT2 PGK1 0 0 289 314 1 2
    SIRT2 CDK19 0 0 451 481 1 1
    SIRT2 KAT2A 270 0 666 803 1 1
    SIRT2 DHDH 0 0 0 165 1 1
    SIRT2 PHF11 0 0 0 165 1 1
    SIRT2 PIWIL4 0 0 229 228 1 1
    SIRT2 LEPR 0 0 161 161 1 1
    SIRT2 MCM4 0 0 112 203 1 1
    SIRT2 SDHA 0 0 275 325 1 1
    SIRT2 CASP8 0 0 283 282 1 2
    SIRT2 TUBB3 0 0 100 151 1 1
    SIRT2 TNK2 0 0 235 282 1 1
    SIRT2 TICRR 0 0 134 152 1 1
    SIRT2 CHRAC1 0 0 0 164 1 1
    SIRT2 LIG3 0 0 160 233 1 1
    SIRT2 ADCY5 0 0 138 157 1 1
    SIRT2 DHRS12 0 0 103 263 1 1
    SIRT2 HIST2H3D 0 0 43 187 1 1
    SIRT2 HCFC1 0 0 123 163 1 1
    SIRT2 HIST1H4J 0 0 686 745 1 1
    SIRT2 GLI3 0 0 179 193 1 1
    SIRT2 NAA15 0 0 150 168 1 1
    SIRT2 KRT78 211 0 0 228 1 1
    SIRT2 HSPE1 0 0 181 186 1 1
    SIRT2 KEAP1 0 0 376 390 1 2
    SIRT2 GLO1 0 0 81 156 1 1
    SIRT2 PROM1 0 0 140 152 1 1
    SIRT2 SIRT3 0 0 806 175 1 2
    SIRT2 KMT2C 0 0 124 237 1 1
    SIRT2 TLE1 0 0 102 158 1 1
    SIRT2 DNMT1 0 0 502 517 1 1
    SIRT2 STUB1 0 0 260 276 1 2
    SIRT2 CTTN 0 0 379 379 1 1
    SIRT2 ACTB 0 0 459 480 1 1
    SIRT2 FOXJ3 0 0 57 184 1 1
    SIRT2 INS 0 0 654 654 1 1
    SIRT2 FOXG1 0 0 142 714 1 1
    SIRT2 ASH1L 0 0 123 237 1 1
    SIRT2 KDM1B 0 0 260 321 1 1
    SIRT2 SETBP1 0 0 0 165 1 1
    SIRT2 DYRK2 0 0 46 199 1 1
    SIRT2 SUV39H1 0 900 464 951 1 1
    SIRT2 COX4I1 0 0 203 203 1 1
    SIRT2 NEUROD1 0 0 134 153 1 1
    SIRT2 ATP5S 0 0 0 209 1 1
    SIRT2 HTRA2 0 0 171 186 1 1
    SIRT2 SETD1A 0 0 460 570 1 1
    SIRT2 CEBPA 0 0 252 269 1 1
    SIRT2 COQ7 0 0 113 152 1 1
    SIRT2 WRN 0 0 423 520 1 1
    SIRT2 HPGDS 0 0 444 444 1 1
    SIRT2 FBXW7 0 0 134 257 1 1
    SIRT2 FOSL1 0 0 93 163 1 1
    SIRT2 TFEB 0 0 217 243 1 2
    SIRT2 SETDB1 0 0 242 340 1 1
    SIRT2 PNPLA2 0 0 244 243 1 1
    SIRT2 FOXD3 0 0 0 166 1 1
    SIRT2 TUBA1B 0 900 0 909 1 1
    SIRT2 GABARAPL1 0 0 345 400 1 2
    SIRT2 SIRT7 0 0 759 486 1 1
    SIRT2 ZEB1 0 0 181 181 1 1
    SIRT2 FEN1 0 0 163 274 1 1
    SIRT2 EPC1 0 0 170 222 1 1
    SIRT2 ESR2 0 0 203 233 1 1
    SIRT2 TRPT1 0 0 108 180 1 1
    SIRT2 RAB1A 0 0 359 374 1 2
    SIRT2 ISOC2 0 0 0 264 1 1
    SIRT2 SETMAR 0 0 75 202 1 1
    SIRT2 GABPB1 0 0 170 221 1 1
    SIRT2 HIST1H2BL 0 0 0 170 1 1
    SIRT2 TARDBP 0 0 161 161 1 1
    SIRT2 PIWIL1 0 0 231 247 1 1
    SIRT2 KDM1A 0 0 466 510 1 1
    SIRT2 PGAM2 0 0 94 156 1 1
    SIRT2 CRTC2 0 0 327 327 1 1
    SIRT2 HSPA8 0 0 233 332 1 2
    SIRT2 SPO11 0 0 193 241 1 1
    SIRT2 GSR 0 0 320 334 1 1
    SIRT2 NUP50 0 0 75 154 1 1
    SIRT2 RHOA 0 0 167 167 1 1
    SIRT2 PARP1 0 0 707 714 1 2
    SIRT2 NKRF 0 0 269 281 1 1
    SIRT2 SAT1 0 0 91 234 1 1
    SIRT2 TFAM 0 0 421 448 1 1
    SIRT2 ATP5B 0 0 150 300 1 1
    SIRT2 FZR1 270 0 92 455 1 1
    SIRT2 HIST2H3C 0 0 44 188 1 1
    SIRT2 MMP2 0 0 194 195 1 1
    SIRT2 XRN1 0 0 58 155 1 1
    SIRT2 STYX 0 0 0 156 1 1
    SIRT2 ITGB1BP2 0 0 166 165 1 1
    SIRT2 CSTF3 0 0 0 152 1 1
    SIRT2 CALR 0 0 151 150 1 1
    SIRT2 CD8A 0 0 193 193 1 1
    SIRT2 DNA2 0 0 171 226 1 1
    SIRT2 ENPP6 0 0 218 260 1 1
    SIRT2 SMYD3 0 0 171 278 1 1
    SIRT2 DUSP22 0 0 0 156 1 1
    SIRT2 PRDX1 0 0 203 218 1 1
    SIRT2 ELP3 0 0 425 561 1 1
    SIRT2 MYRF 0 0 181 198 1 1
    SIRT2 KDM4A 0 0 342 352 1 1
    SIRT2 TET3 0 0 203 257 1 1
    SIRT2 NKX2-2 0 0 164 178 1 1
    SIRT2 SPOP 402 0 96 436 1 1
    SIRT2 LAMP2 0 0 123 155 1 2
    SIRT2 VCP 0 0 134 176 1 2
    SIRT2 YWHAE 0 0 0 177 1 1
    SIRT2 ZNF629 0 0 190 204 1 1
    SIRT2 C10orf12 0 0 0 207 1 1
    SIRT2 DLL4 0 0 82 159 1 1
    SIRT2 TSC1 0 0 150 169 1 2
    SIRT2 TNKS 0 0 306 357 1 1
    SIRT2 KPNB1 0 0 108 183 1 1
    SIRT2 WDR5 0 0 236 257 1 1
    SIRT2 BCL2L11 0 0 391 390 1 1
    SIRT2 PHF13 0 0 0 166 1 1
    SIRT2 BRD3 0 0 244 362 1 1
    SIRT2 KL 0 0 378 378 1 1
    SIRT2 NRF1 0 0 366 366 1 1
    SIRT2 SRF 0 0 208 222 1 1
    SIRT2 SLC25A31 0 0 0 153 1 1
    SIRT2 HSPA1A 0 0 171 305 1 1
    SIRT2 TNFSF10 0 0 166 165 1 2
    SIRT2 CDC20 270 0 457 639 1 1
    SIRT2 PER2 0 0 401 430 1 1
    SIRT2 ULK2 0 0 135 152 1 2
    SIRT2 PRPSAP2 0 0 0 151 1 1
    SIRT2 NADK2 0 900 112 909 1 1
    SIRT2 SNCA 0 0 556 573 1 2
    SIRT2 SLC16A3 0 0 161 161 1 1
    SIRT2 NNMT 0 900 450 942 1 1
    SIRT2 CHEK1 0 0 262 324 1 1
    SIRT2 SLC25A27 0 0 164 239 1 1
    SIRT2 MALSU1 0 0 106 240 1 1
    SIRT2 MPZL1 0 0 62 205 1 1
    SIRT2 CASP1 0 0 243 242 1 2
    SIRT2 DNMT3A 0 0 392 392 1 1
    SIRT2 XPA 0 0 231 259 1 1
    SIRT2 UHRF1 0 0 156 174 1 1
    SIRT2 PROSER3 0 0 90 182 1 1
    SIRT2 ALDOA 0 0 134 187 1 1
    SIRT2 DNMT3B 0 0 544 544 1 1
    SIRT2 ANAPC5 0 0 398 398 1 1
    SIRT2 BCL2L1 0 0 366 366 1 2
    SIRT2 RECQL 0 0 62 219 1 1
    SIRT2 TUBB4A 0 0 96 168 1 1
    SIRT2 ACSS2 0 0 517 547 1 1
    SIRT2 ME1 0 0 123 165 1 1
    SIRT2 RAN 800 0 84 808 1 1
    SIRT2 FOXD4L5 0 0 0 166 1 1
    SIRT2 SH2D1B 0 0 261 289 1 1
    SIRT2 TFB1M 0 0 124 151 1 1
    SIRT2 SLC25A20 0 0 112 191 1 1
    SIRT2 ATRX 0 0 210 254 1 1
    SIRT2 RPS6KA5 0 0 166 176 1 1
    SIRT2 GABARAPL2 0 0 367 420 1 2
    SIRT2 NOS2 0 0 166 185 1 1
    SIRT2 TLR4 0 0 284 295 1 1
    SIRT2 SMAD2 0 0 168 417 1 1
    SIRT2 NMNAT1 0 650 595 872 1 1
    SIRT2 OLIG1 0 0 204 255 1 1
    SIRT2 ATG14 0 0 145 163 1 2
    SIRT2 CHD7 0 0 314 352 1 1
    SIRT2 BIRC2 0 0 81 161 1 1
    SIRT2 PDHA2 0 0 0 151 1 1
    SIRT2 TENC1 0 0 0 156 1 1
    SIRT2 PDXK 0 0 306 316 1 1
    SIRT2 NFATC2IP 0 0 214 234 1 1
    SIRT2 DUSP15 0 0 0 156 1 1
    SIRT2 EP400 0 0 150 276 1 1
    SIRT2 LONP1 0 0 154 227 1 1
    SIRT2 JHDM3C 0 0 155 168 1 1
    SIRT2 HSPA1L 0 0 46 191 1 1
    SIRT2 RAD50 0 0 66 194 1 1
    SIRT2 KLF3 0 0 108 214 1 1
    SIRT2 RANBP2 0 0 71 150 1 1
    SIRT2 RELN 0 0 108 197 1 1
    SIRT2 PLK1 0 0 213 277 1 1
    SIRT2 EPO 0 0 232 231 1 1
    SIRT2 GPD1 0 0 107 181 1 1
    SIRT2 CCNB1 0 0 193 207 1 1
    SIRT2 CS 0 0 321 349 1 1
    SIRT2 ANXA5 0 0 294 294 1 1
    SIRT2 GRIA2 0 0 134 180 1 1
    SIRT2 FGF21 0 0 335 335 1 1
    SIRT2 HES1 0 0 61 151 1 1
    SIRT2 WHSC1 0 0 215 317 1 1
    SIRT2 FOXM1 0 0 218 319 1 1
    SIRT2 HSPD1 0 0 155 178 1 1
    SIRT2 MGMT 0 0 134 211 1 1
    SIRT2 SMARCAD1 0 0 46 235 1 1
    SIRT2 GLYATL1 0 0 595 595 1 1
    SIRT2 POTEF 0 0 146 180 1 1
    SIRT2 KAT7 0 0 367 555 1 1
    SIRT2 PIDD1 0 0 72 167 1 1
    SIRT2 PSEN2 0 0 195 195 1 1
    SIRT2 SCO2 0 0 217 217 1 1
    SIRT2 NOTCH1 0 0 310 321 1 1
    SIRT2 PTGS1 0 0 124 178 1 1
    SIRT2 PRMT1 0 0 294 322 1 1
    SIRT2 P4HTM 0 0 0 161 1 1
    SIRT2 FOXO6 0 0 381 529 1 1
    SIRT2 BRD2 0 0 277 390 1 1
    SIRT2 NAP1L1 0 0 0 204 1 1
    SIRT2 CBX3 0 0 202 325 1 1
    SIRT2 H3F3A 0 0 74 256 1 1
    SIRT2 ATRIP 0 0 150 173 1 1
    SIRT2 UCP2 0 0 495 535 1 1
    SIRT2 MSC 0 0 636 642 1 1
    SIRT2 NFYB 0 0 116 312 1 1
    SIRT2 IL6 0 0 457 457 1 1
    SIRT2 NUDT15 0 0 0 177 1 1
    SIRT2 USP41 0 0 0 218 1 1
    SIRT2 CLN3 0 0 103 178 1 2
    SIRT2 NDUFS4 0 0 203 203 1 1
    SIRT2 SIRT5 0 0 756 538 1 1
    SIRT2 GCK 0 0 251 282 1 1
    SIRT2 SMAD9 0 0 57 194 1 1
    SIRT2 EDN1 0 0 162 161 1 1
    SIRT2 HIF1A 270 0 560 669 1 2
    SIRT2 ASB18 0 0 67 167 1 1
    SIRT2 SETD5 0 0 0 215 1 1
    SIRT2 NKX6-2 0 0 102 171 1 1
    SIRT2 SP1 0 0 157 171 1 1
    SIRT2 IL1B 0 0 417 416 1 1
    SIRT2 PLA2G4A 270 0 430 611 1 1
    SIRT2 FOXD4L4 0 0 0 166 1 1
    SIRT2 ACSL5 0 0 318 328 1 1
    SIRT2 XPO1 0 0 397 419 1 1
    SIRT2 PRKAG1 0 0 85 150 1 1
    SIRT2 MAP1LC3A 0 0 143 279 1 2
    SIRT2 CDK2 270 0 470 614 1 1
    SIRT2 SHMT2 0 0 125 170 1 1
    SIRT2 UPK2 0 0 0 166 1 1
    SIRT2 NAPRT 0 0 503 607 1 1
    SIRT2 CAMKK2 0 0 151 194 1 2
    SIRT2 FOXE3 0 0 0 166 1 1
    SIRT2 BAZ2A 0 720 143 788 1 1
    SIRT2 PDXP 0 0 54 223 1 1
    SIRT2 SETD8 0 0 289 381 1 1
    SIRT2 COL2A1 0 0 274 282 1 1
    SIRT2 KDM7A 0 0 118 280 1 1
    SIRT2 EXOSC10 0 0 157 180 1 1
    SIRT2 CD55 0 0 201 201 1 1
    SIRT2 AGO2 0 0 108 169 1 1
    SIRT2 EZH2 0 0 383 463 1 1
    SIRT2 STAT3 0 0 405 405 1 2
    SIRT2 CPT2 0 0 155 175 1 1
    SIRT2 VDAC2 0 0 160 159 1 1
    SIRT2 ERN1 0 0 194 194 1 2
    SIRT2 XRCC6 0 0 559 627 1 1
    SIRT2 MTAP 0 0 112 198 1 1
    SIRT2 PSMD13 0 0 129 193 1 1
    SIRT2 ELAVL2 0 0 181 181 1 1
    SIRT2 ENPP3 0 650 0 654 1 1
    SIRT2 SARM1 0 0 213 213 1 1
    SIRT2 CDK4 0 0 261 293 1 1
    SIRT2 HIST1H4I 0 0 686 745 1 1
    SIRT2 METAP2 0 0 163 176 1 1
    SIRT2 CCRN4L 0 0 112 150 1 1
    SIRT2 TUBA4A 270 0 108 394 1 1
    SIRT2 GART 274 0 0 436 1 1
    SIRT2 TRIM24 0 0 141 177 1 1
    SIRT2 FOXS1 0 0 0 166 1 1
    SIRT2 DDIT3 0 0 183 202 1 2
    SIRT2 ZNF44 0 0 186 200 1 1
    SIRT2 MCAT 0 0 150 170 1 1
    SIRT2 PLP1 0 0 283 316 1 1
    SIRT2 RMI1 0 0 134 167 1 1
    SIRT2 ASPH 0 0 268 318 1 1
    SIRT2 SLC25A4 0 0 123 248 1 1
    SIRT2 ACSL6 0 0 325 355 1 1
    SIRT2 SLC2A2 0 0 146 171 1 1
    SIRT2 LMNA 0 0 283 308 1 1
    SIRT2 EXO1 0 0 187 295 1 1
    SIRT2 TTLL10 0 0 107 213 1 1
    SIRT2 HK2 0 0 310 339 1 1
    SIRT2 PARD3 0 0 56 504 1 1
    SIRT2 HIPK4 0 0 0 184 1 1
    SIRT2 FXN 0 0 321 321 1 1
    SIRT2 CEP97 0 0 147 280 1 1
    SIRT2 PARK7 0 0 270 347 1 1
    SIRT2 ACSL1 0 0 144 157 1 1
    SIRT2 COX7A2 0 0 0 213 1 1
    SIRT2 SMAD4 0 0 184 264 1 1
    SIRT2 MYCN 0 0 235 263 1 1
    SIRT2 HIST1H4L 0 0 686 745 1 1
    SIRT2 HDAC3 0 0 701 817 1 1
    SIRT2 MEF2D 0 0 150 172 1 1
    SIRT2 EIF5B 0 0 145 217 1 1
    SIRT2 TDO2 0 0 243 273 1 1
    SIRT2 HDAC5 0 0 492 655 1 1
    SIRT2 PFKM 0 0 244 243 1 1
    SIRT2 SCML2 0 0 0 260 1 1
    SIRT2 BRD9 0 0 202 319 1 1
    SIRT2 NPY 0 0 232 231 1 1
    SIRT2 ODC1 0 0 126 240 1 1
    SIRT2 MFF 0 0 167 167 1 1
    SIRT2 VPS72 0 0 122 172 1 1
    SIRT2 UNK 174 0 0 192 1 1
    SIRT2 HIST1H2BM 0 0 0 170 1 1
    SIRT2 PPIF 0 0 425 434 1 1
    SIRT2 MAP2K1 0 0 165 179 1 1
    SIRT2 PGAM5 0 0 153 152 1 1
    SIRT2 EHMT2 0 0 395 473 1 1
    SIRT2 NFE2L2 0 0 425 458 1 1
    SIRT2 BCL7A 0 0 306 306 1 1
    SIRT2 MECP2 0 0 325 344 1 1
    SIRT2 CAB39 0 0 113 231 1 1
    SIRT2 CDH15 0 0 0 207 1 1
    SIRT2 AKT2 0 0 212 252 1 1
    SIRT2 ENSG00000272772 0 0 0 197 1 1
    SIRT2 SDHC 0 0 184 235 1 1
    SIRT2 IGF1R 0 0 267 267 1 1
    SIRT2 HIST1H2BD 0 0 0 170 1 1
    SIRT2 ANKRD28 0 0 0 192 1 1
    SIRT2 H1F0 0 0 407 428 1 1
    SIRT2 STK32B 0 0 0 157 1 1
    SIRT2 APEX1 0 0 195 261 1 1
    SIRT2 MYC 270 0 562 671 1 2
    SIRT2 PDK1 0 0 208 228 1 1
    SIRT2 HIPK1 0 0 0 344 1 1
    SIRT2 IL18 0 0 261 261 1 1
    SIRT2 PARP12 0 0 154 153 1 1
    SIRT2 CDYL 0 0 123 259 1 1
    SIRT2 TPI1 0 0 184 201 1 1
    SIRT2 SBNO2 0 0 0 304 1 1
    SIRT2 TOP3A 0 0 127 203 1 1
    SIRT2 PIK3CA 0 0 135 218 1 2
    SIRT2 CAMKMT 0 0 268 268 1 1
    SIRT2 ACACA 0 0 181 196 1 1
    SIRT2 GLS 0 0 195 199 1 1
    SIRT2 FBP2 0 0 73 217 1 1
    SIRT2 NTS 0 0 308 308 1 1
    SIRT2 RUVBL2 0 0 213 244 1 1
    SIRT2 ATP5G3 0 0 91 241 1 1
    SIRT2 MSRA 0 0 166 165 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
    GO:0070403 Molecular Function NAD+ binding enables IBA
    GO:0070403 Molecular Function NAD+ binding enables IDA
    GO:0003950 Molecular Function NAD+ poly-ADP-ribosyltransferase activity enables IDA
    GO:0003950 Molecular Function NAD+ poly-ADP-ribosyltransferase activity NOT enables TAS
    GO:1990404 Molecular Function NAD+-protein mono-ADP-ribosyltransferase activity NOT enables TAS
    GO:0140773 Molecular Function NAD-dependent protein demyristoylase activity enables IDA
    GO:0140774 Molecular Function NAD-dependent protein depalmitoylase activity enables IDA
    GO:0034979 Molecular Function NAD-dependent protein lysine deacetylase activity enables IDA
    GO:0034979 Molecular Function NAD-dependent protein lysine deacetylase activity enables IMP
    GO:0034979 Molecular Function NAD-dependent protein lysine deacetylase activity enables TAS
    GO:0003682 Molecular Function chromatin binding enables IDA
    GO:0032041 Molecular Function histone H3K14 deacetylase activity, NAD-dependent enables IEA
    GO:0097372 Molecular Function histone H3K18 deacetylase activity, NAD-dependent enables IEA
    GO:0141222 Molecular Function histone H3K4 deacetylase activity, NAD-dependent enables IEA
    GO:0140765 Molecular Function histone H3K56 deacetylase activity, NAD-dependent enables IEA
    GO:0046969 Molecular Function histone H3K9 deacetylase activity, NAD-dependent enables IEA
    GO:0046970 Molecular Function histone H4K16 deacetylase activity, NAD-dependent enables IDA
    GO:0035035 Molecular Function histone acetyltransferase binding enables IPI
    GO:0004407 Molecular Function histone deacetylase activity enables IDA
    GO:0017136 Molecular Function histone deacetylase activity, NAD-dependent enables IBA
    GO:0017136 Molecular Function histone deacetylase activity, NAD-dependent NOT enables IDA
    GO:0017136 Molecular Function histone deacetylase activity, NAD-dependent enables IDA
    GO:0042826 Molecular Function histone deacetylase binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0033558 Molecular Function protein lysine deacetylase activity enables IDA
    GO:0033558 Molecular Function protein lysine deacetylase activity enables IMP
    GO:0042903 Molecular Function tubulin deacetylase activity NOT enables IDA
    GO:0042903 Molecular Function tubulin deacetylase activity enables IDA
    GO:0043130 Molecular Function ubiquitin binding enables IDA
    GO:0008270 Molecular Function zinc ion binding enables IDA
    GO:0044546 Biological Process NLRP3 inflammasome complex assembly involved_in IEA
    GO:0006914 Biological Process autophagy involved_in IEA
    GO:0051301 Biological Process cell division involved_in IEA
    GO:0061433 Biological Process cellular response to caloric restriction involved_in ISS
    GO:0071872 Biological Process cellular response to epinephrine stimulus involved_in ISS
    GO:0071456 Biological Process cellular response to hypoxia involved_in IDA
    GO:0034599 Biological Process cellular response to oxidative stress involved_in ISS
    GO:0040029 Biological Process epigenetic regulation of gene expression involved_in IMP
    GO:0031507 Biological Process heterochromatin formation involved_in NAS
    GO:0045087 Biological Process innate immune response involved_in IEA
    GO:0016042 Biological Process lipid catabolic process involved_in ISS
    GO:0051321 Biological Process meiotic cell cycle involved_in IEA
    GO:0007084 Biological Process mitotic nuclear membrane reassembly involved_in TAS
    GO:0022011 Biological Process myelination in peripheral nervous system involved_in ISS
    GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
    GO:1900226 Biological Process negative regulation of NLRP3 inflammasome complex assembly involved_in IEA
    GO:0010507 Biological Process negative regulation of autophagy involved_in IMP
    GO:0045599 Biological Process negative regulation of fat cell differentiation involved_in ISS
    GO:0070446 Biological Process negative regulation of oligodendrocyte progenitor proliferation involved_in ISS
    GO:0010801 Biological Process negative regulation of peptidyl-threonine phosphorylation involved_in ISS
    GO:0042177 Biological Process negative regulation of protein catabolic process involved_in IMP
    GO:2000378 Biological Process negative regulation of reactive oxygen species metabolic process involved_in ISS
    GO:1902725 Biological Process negative regulation of satellite cell differentiation involved_in ISS
    GO:0045843 Biological Process negative regulation of striated muscle tissue development involved_in IDA
    GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IDA
    GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IMP
    GO:0034983 Biological Process peptidyl-lysine deacetylation involved_in IDA
    GO:0043388 Biological Process positive regulation of DNA binding involved_in ISS
    GO:0051987 Biological Process positive regulation of attachment of spindle microtubules to kinetochore involved_in ISS
    GO:0051781 Biological Process positive regulation of cell division involved_in ISS
    GO:1900119 Biological Process positive regulation of execution phase of apoptosis involved_in ISS
    GO:0045723 Biological Process positive regulation of fatty acid biosynthetic process involved_in IDA
    GO:0045836 Biological Process positive regulation of meiotic nuclear division involved_in ISS
    GO:1900195 Biological Process positive regulation of oocyte maturation involved_in ISS
    GO:0032436 Biological Process positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved_in IMP
    GO:0032436 Biological Process positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved_in ISS
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
    GO:0043687 Biological Process post-translational protein modification involved_in IEA
    GO:0043161 Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process involved_in IMP
    GO:0006476 Biological Process protein deacetylation NOT involved_in IDA
    GO:0006476 Biological Process protein deacetylation involved_in IDA
    GO:0000183 Biological Process rDNA heterochromatin formation involved_in IBA
    GO:0000183 Biological Process rDNA heterochromatin formation involved_in NAS
    GO:0051726 Biological Process regulation of cell cycle involved_in IMP
    GO:0007096 Biological Process regulation of exit from mitosis involved_in NAS
    GO:0031641 Biological Process regulation of myelination involved_in ISS
    GO:0042325 Biological Process regulation of phosphorylation involved_in NAS
    GO:0051775 Biological Process response to redox state involved_in NAS
    GO:0021762 Biological Process substantia nigra development involved_in HEP
    GO:0031509 Biological Process subtelomeric heterochromatin formation involved_in NAS
    GO:0090042 Biological Process tubulin deacetylation NOT involved_in IDA
    GO:0090042 Biological Process tubulin deacetylation involved_in IDA
    GO:0090042 Biological Process tubulin deacetylation involved_in ISS
    GO:0043220 Cellular Component Schmidt-Lanterman incisure located_in ISS
    GO:0005814 Cellular Component centriole located_in IDA
    GO:0005813 Cellular Component centrosome located_in IDA
    GO:0005677 Cellular Component chromatin silencing complex part_of NAS
    GO:0005694 Cellular Component chromosome located_in IDA
    GO:0000781 Cellular Component chromosome, telomeric region located_in IEA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0097386 Cellular Component glial cell projection located_in ISS
    GO:0030426 Cellular Component growth cone located_in IEA
    GO:0000792 Cellular Component heterochromatin located_in ISS
    GO:0044224 Cellular Component juxtaparanode region of axon located_in ISS
    GO:0043219 Cellular Component lateral loop located_in ISS
    GO:0072687 Cellular Component meiotic spindle located_in ISS
    GO:0005874 Cellular Component microtubule located_in IDA
    GO:0030496 Cellular Component midbody located_in IDA
    GO:0005739 Cellular Component mitochondrion located_in HTP
    GO:0072686 Cellular Component mitotic spindle located_in IDA
    GO:0043209 Cellular Component myelin sheath located_in ISS
    GO:0005730 Cellular Component nucleolus located_in IDA
    GO:0005634 Cellular Component nucleus is_active_in IBA
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0033010 Cellular Component paranodal junction located_in ISS
    GO:0033270 Cellular Component paranode region of axon located_in ISS
    GO:0043204 Cellular Component perikaryon located_in ISS
    GO:0048471 Cellular Component perinuclear region of cytoplasm located_in ISS
    GO:0005886 Cellular Component plasma membrane located_in IDA
    GO:0005819 Cellular Component spindle located_in IDA
    Pathways
    Name DB ID
    Cell Cycle Reactome R-HSA-1640170
    Mitotic Metaphase and Anaphase Reactome R-HSA-2555396
    Initiation of Nuclear Envelope (NE) Reformation Reactome R-HSA-2995383
    Nuclear Envelope (NE) Reassembly Reactome R-HSA-2995410
    Mitotic Anaphase Reactome R-HSA-68882
    M Phase Reactome R-HSA-68886
    Cell Cycle, Mitotic Reactome R-HSA-69278
    NAD+ metabolism (WP3644) WikiPathways WP3644_r118983
    NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence (WP5046) WikiPathways WP5046_r118987
    NAD+ biosynthetic pathways (WP3645) WikiPathways WP3645_r123910
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_034146 1 miscRNA transcript variant 4 NC_000019 Reference
    XM_011526655 2 mRNA transcript variant X2 NC_000019 Reference
    NM_001193286 2 mRNA transcript variant 3 NC_000019 Reference
    NM_030593 3 mRNA transcript variant 2 NC_000019 Reference
    NM_012237 4 mRNA transcript variant 1 NC_000019 Reference
    XM_047438468 1 mRNA transcript variant X1 NC_000019 Reference
    XM_047438469 1 mRNA transcript variant X3 NC_000019 Reference