ELAPOR2

endosome-lysosome associated apoptosis and autophagy regulator family member 2
General Information
Name endosome-lysosome associated apoptosis and autophagy regulator family member 2
Alias
  • endosome/lysosome-associated apoptosis and autophagy regulator family member 2
  • EIG121-like
  • KIAA1324 like
  • UPF0577 protein KIAA1324-like
  • estrogen-induced gene 121-like protein
Synonyms FLJ31340 EIG121L KIAA1324L
Gene_family None
organism Homo sapiens
entrez_id 222223
location 7q21.12
transcript_count 11
exon_count 27
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Predicted to enable BMP receptor binding activity. Predicted to be involved in negative regulation of nervous system development; positive regulation of BMP signaling pathway; and positive regulation of epidermis development. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Mar 2025]
      nextProt Functions as a regulator of the BMP signaling pathway and may be involved in epidermal differentiation.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ELAPOR2 BioGRID PRNP GeneID BioGRID Affinity Capture-MS
    ELAPOR2 BioGRID SIGLECL1 GeneID BioGRID Affinity Capture-MS
    ELAPOR2 BioGRID ARMH4 GeneID BioGRID Affinity Capture-MS
    ELAPOR2 BioGRID SDC2 GeneID BioGRID Affinity Capture-MS
    ELAPOR2 BioGRID LAMTOR1 GeneID BioGRID Proximity Label-MS
    ELAPOR2 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
    StringDB
    A B experiments database textmining combined score hadb nhadb
    KIAA1324L MAPK8 0 0 0 161 2 1
    KIAA1324L DAPK1 0 0 115 208 2 1
    KIAA1324L PSEN1 0 0 0 176 2 1
    KIAA1324L SQSTM1 0 0 0 174 2 1
    KIAA1324L ERBB2 0 0 0 164 2 1
    KIAA1324L NBR1 0 0 0 174 2 1
    KIAA1324L MAPK10 0 0 134 267 2 1
    KIAA1324L CTSB 0 0 0 195 2 1
    KIAA1324L LRRK2 0 0 75 246 2 1
    KIAA1324L PRKAR1A 0 0 134 152 2 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0070700 Molecular Function BMP receptor binding enables ISS
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0051961 Biological Process negative regulation of nervous system development involved_in ISS
    GO:0030513 Biological Process positive regulation of BMP signaling pathway involved_in IBA
    GO:0030513 Biological Process positive regulation of BMP signaling pathway involved_in ISS
    GO:0045684 Biological Process positive regulation of epidermis development involved_in ISS
    GO:0016020 Cellular Component membrane is_active_in IBA
    GO:0005886 Cellular Component plasma membrane located_in ISS
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_011515918 3 mRNA transcript variant X2 NC_000007 Reference
    XM_011515921 2 mRNA transcript variant X6 NC_000007 Reference
    XM_017011843 2 mRNA transcript variant X3 NC_000007 Reference
    NM_001142749 3 mRNA transcript variant 1 NC_000007 Reference
    NM_001291991 2 mRNA transcript variant 4 NC_000007 Reference
    NM_001291990 1 mRNA transcript variant 3 NC_000007 Reference
    XM_047420042 1 mRNA transcript variant X5 NC_000007 Reference
    NM_152748 4 mRNA transcript variant 2 NC_000007 Reference
    XM_006715894 4 mRNA transcript variant X4 NC_000007 Reference
    XM_024446686 2 mRNA transcript variant X7 NC_000007 Reference
    XM_047420041 1 mRNA transcript variant X1 NC_000007 Reference