SOGA1

suppressor of glucose, autophagy associated 1
General Information
Name suppressor of glucose, autophagy associated 1
Alias
  • protein SOGA1
  • SOGA family member 1
  • suppressor of glucose by autophagy
  • suppressor of glucose from autophagy
  • suppressor of glucose, autophagy-associated protein 1
Synonyms dJ132F21.1 FLJ44670 SOGA C20orf117 KIAA0889
Gene_family None
organism Homo sapiens
entrez_id 140710
location 20q11.23
transcript_count 2
exon_count 16
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Involved in chromosome segregation. Located in extracellular space; microtubule; and midbody. [provided by Alliance of Genome Resources, Mar 2025]
      Stringdb Protein SOGA1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner; Belongs to the SOGA family
      nextProt Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    MTCL2 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS; Cross-Linking-MS (XL-MS); Proximity Label-MS
    MTCL2 BioGRID YTHDF1 GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID IGF2BP2 GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID IGF2BP3 GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID IGF2BP1 GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID PRKAG1 GeneID BioGRID Affinity Capture-Western
    MTCL2 BioGRID PRKAB1 GeneID BioGRID Affinity Capture-Western
    MTCL2 BioGRID PRKAA1 GeneID BioGRID Affinity Capture-Western
    MTCL2 BioGRID HAPSTR1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SPTAN1 GeneID BioGRID Cross-Linking-MS (XL-MS)
    MTCL2 BioGRID YWHAQ GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    MTCL2 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    MTCL2 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    MTCL2 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    MTCL2 BioGRID GSK3B GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID GSK3A GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID SFN GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID RAF1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID RNF113A GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID MARK3 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID MARK2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID UBE2O GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SOX2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID DYNLL2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID DYNLL1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PPP2CA GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SIRT6 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID COP1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF219 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID VPS33B GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID ZNF460 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PNMA2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID RNF41 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID AKAP9 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF263 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID MAP7 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF26 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID TSNAX GeneID BioGRID Affinity Capture-MS; Two-hybrid
    MTCL2 BioGRID PPP2R5A GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PPP2R1A GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SMAD4 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID JUN GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID GLI4 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF584 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF169 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF785 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ZNF689 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID LZTS2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID CCDC77 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID VPS33A GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID DCTN1 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID TRIM36 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID BORCS6 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID CAMSAP2 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID KDM1A GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID MAPRE3 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID NDC80 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID ACTR3 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID LATS1 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID VIM GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID PXN GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID PFN1 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID KRT8 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID DNAJB13 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID ANLN GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID BRPF3 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID BRD1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID KIF14 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID TRIM66 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID KIF23 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID AURKB GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PRC1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SLC25A25 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID JPH2 GeneID BioGRID Proximity Label-MS
    MTCL2 BioGRID NUTM1 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID FAM161A GeneID BioGRID Two-hybrid
    MTCL2 BioGRID EFHC2 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID NECAB2 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID HDAC7 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID AMOTL2 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID TFIP11 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID PPP1R13B GeneID BioGRID Two-hybrid
    MTCL2 BioGRID LZTS1 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID STX11 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID BHLHE40 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID ZNF20 GeneID BioGRID Two-hybrid
    MTCL2 BioGRID RORB GeneID BioGRID Two-hybrid
    MTCL2 BioGRID CYLD GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PSMD14 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID HNRNPL GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
    MTCL2 BioGRID Cul4a GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Set GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Ppp2r1a GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Kif20a GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Mark2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID LDHD GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SAMHD1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID NOP56 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID HERC2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID ANKRA2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID RFXANK GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID NTRK1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID CCDC8 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID SIRT7 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Mtcl2 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID Dynll1 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID MARK4 GeneID BioGRID Affinity Capture-MS
    MTCL2 BioGRID PLEKHA5 GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    SOGA1 PHF20 0 0 155 154 1 1
    SOGA1 CSMD3 0 0 181 181 1 1
    SOGA1 DHX35 0 0 300 300 1 1
    SOGA1 ANKRA2 270 0 0 270 1 1
    SOGA1 NDUFB10 0 0 212 212 1 1
    SOGA1 GFPT2 0 0 321 337 1 1
    SOGA1 GRK5 0 0 294 541 1 1
    SOGA1 ST8SIA4 0 0 57 160 1 1
    SOGA1 ECHS1 0 0 167 255 1 1
    SOGA1 BRPF3 154 0 0 153 1 1
    SOGA1 ATP5H 0 0 170 169 1 1
    SOGA1 ADIPOR2 0 0 162 161 1 1
    SOGA1 ATG2B 0 0 194 204 1 2
    SOGA1 TIMM8A 0 0 235 274 1 1
    SOGA1 MC4R 0 0 181 308 1 1
    SOGA1 ATG4C 0 0 170 180 1 2
    SOGA1 ZFPM2 0 0 253 317 1 1
    SOGA1 CDC37L1 0 0 261 280 1 1
    SOGA1 TAF4 0 0 66 209 1 1
    SOGA1 SLC25A5 0 0 155 154 1 1
    SOGA1 FLT1 305 0 0 305 1 1
    SOGA1 ATPIF1 0 0 211 211 1 1
    SOGA1 MICAL3 0 0 92 155 1 1
    SOGA1 FTCDNL1 0 0 217 217 1 1
    SOGA1 EPG5 0 0 234 249 1 2
    SOGA1 ATP5F1 0 0 181 181 1 1
    SOGA1 KIF23 270 0 0 270 1 1
    SOGA1 ITSN1 0 0 166 185 1 1
    SOGA1 GNPNAT1 0 0 89 487 1 1
    SOGA1 ZC3H12D 0 0 452 452 1 1
    SOGA1 ATG2A 0 0 203 214 1 2
    SOGA1 L2HGDH 0 0 107 266 1 1
    SOGA1 KIF14 270 0 0 270 1 1
    SOGA1 HERC2 270 0 0 296 1 1
    SOGA1 TSNAX 474 0 0 474 1 1
    SOGA1 PRC1 270 0 0 270 1 1
    SOGA1 GTF3C5 0 0 142 243 1 1
    SOGA1 PLCB1 0 0 124 156 1 1
    SOGA1 XIRP2 0 0 367 389 1 1
    SOGA1 KRT75 0 0 72 237 1 1
    SOGA1 ABCA6 0 0 235 276 1 1
    SOGA1 ZFYVE26 0 0 218 692 1 1
    SOGA1 WIPI2 0 0 142 175 1 2
    SOGA1 EOGT 0 0 392 722 1 1
    SOGA1 FOXK2 0 0 156 164 1 1
    SOGA1 DRAM1 0 0 246 451 1 2
    SOGA1 PROX1 0 0 181 411 1 1
    SOGA1 RPH3A 0 0 180 208 1 1
    SOGA1 ARHGAP24 0 0 174 192 1 1
    SOGA1 ATG4B 0 0 123 216 1 2
    SOGA1 RNF41 466 0 0 465 1 1
    SOGA1 RFXANK 270 0 0 270 1 1
    SOGA1 NINJ1 0 0 212 212 1 1
    SOGA1 MRPL17 0 0 391 390 1 1
    SOGA1 PSMD14 270 0 0 270 1 1
    SOGA1 AGAP1 0 0 250 349 1 1
    SOGA1 PDZRN3 0 0 218 266 1 1
    SOGA1 IER2 0 0 0 175 1 1
    SOGA1 LRPPRC 0 0 167 167 1 1
    SOGA1 WIPI1 0 0 122 165 1 2
    SOGA1 ACSL4 0 0 134 159 1 1
    SOGA1 MARK2 313 0 124 385 1 1
    SOGA1 GPD2 0 0 167 167 1 1
    SOGA1 MGEA5 0 0 260 424 1 1
    SOGA1 MRPL45 0 0 323 323 1 1
    SOGA1 MAN1A2 0 0 0 187 1 1
    SOGA1 RIMS1 0 0 150 190 1 1
    SOGA1 AMBRA1 0 0 213 230 1 2
    SOGA1 TTC28 0 0 275 275 1 1
    SOGA1 BPHL 0 0 108 198 1 1
    SOGA1 ZNF263 142 0 0 155 1 1
    SOGA1 SGMS2 0 0 204 220 1 1
    SOGA1 BDH1 0 0 167 167 1 1
    SOGA1 SCLY 0 0 288 288 1 1
    SOGA1 SAMHD1 415 0 0 414 1 1
    SOGA1 KCNQ3 0 0 95 198 1 1
    SOGA1 AGPAT9 0 0 180 190 1 1
    SOGA1 GYG1 0 0 218 218 1 1
    SOGA1 HNRNPL 270 0 0 270 1 1
    SOGA1 ATG4D 0 0 180 190 1 2
    SOGA1 GFPT1 0 0 257 319 1 1
    SOGA1 PDE4DIP 0 0 184 256 1 1
    SOGA1 NYAP2 0 0 390 403 1 1
    SOGA1 SNX4 0 0 209 226 1 1
    SOGA1 HAPLN4 0 0 260 303 1 1
    SOGA1 USP49 0 0 254 254 1 1
    SOGA1 CYB5R4 0 0 0 210 1 1
    SOGA1 SKA1 0 0 0 230 1 1
    SOGA1 FOXK1 0 0 172 180 1 1
    SOGA1 ACADSB 0 0 184 183 1 1
    SOGA1 SNCB 0 0 184 227 1 1
    SOGA1 TSPAN7 0 0 202 202 1 1
    SOGA1 SPHKAP 0 0 286 324 1 1
    SOGA1 RSPO2 0 0 150 181 1 1
    SOGA1 ESRRA 0 0 91 184 1 1
    SOGA1 PLGRKT 0 0 284 284 1 1
    SOGA1 ELOVL2 0 0 194 228 1 1
    SOGA1 CIDEC 0 0 134 157 1 1
    SOGA1 IBA57 0 0 261 261 1 1
    SOGA1 MAP1LC3B2 0 0 344 343 1 2
    SOGA1 AGAP2 0 0 0 181 1 1
    SOGA1 DPAGT1 0 0 74 155 1 1
    SOGA1 BCAS4 0 0 422 422 1 1
    SOGA1 TTC34 0 0 418 418 1 1
    SOGA1 COX5B 0 0 184 183 1 1
    SOGA1 MAS1 0 0 233 442 1 1
    SOGA1 UHRF1BP1L 0 0 162 161 1 1
    SOGA1 SLC6A5 0 0 184 198 1 1
    SOGA1 BRD1 154 0 0 153 1 1
    SOGA1 SEC11C 0 0 112 206 1 1
    SOGA1 COX6B1 0 0 177 177 1 1
    SOGA1 KIAA1429 270 0 0 270 1 1
    SOGA1 COQ9 0 0 204 204 1 1
    SOGA1 LDHD 226 0 0 225 1 1
    SOGA1 MARK4 270 0 0 285 1 1
    SOGA1 GNE 0 0 67 163 1 1
    SOGA1 PPP1R12A 0 0 42 190 1 1
    SOGA1 THRA 0 0 171 192 1 1
    SOGA1 FFAR1 0 0 134 165 1 1
    SOGA1 PRSS56 0 0 284 284 1 1
    SOGA1 CLYBL 0 0 95 338 1 1
    SOGA1 PMPCA 0 0 265 265 1 1
    SOGA1 DLGAP1 0 0 161 182 1 1
    SOGA1 MAN1A1 0 0 75 336 1 1
    SOGA1 NDUFS6 0 0 73 153 1 1
    SOGA1 GNPDA1 0 0 172 255 1 1
    SOGA1 RAB3B 0 0 171 190 1 1
    SOGA1 SCN2A 0 0 108 153 1 1
    SOGA1 C6orf58 0 0 0 250 1 1
    SOGA1 APPL1 0 0 244 259 1 1
    SOGA1 CCDC8 270 0 0 270 1 1
    SOGA1 TSFM 0 0 201 201 1 1
    SOGA1 LRP1B 0 0 142 158 1 1
    SOGA1 MEF2D 0 0 215 215 1 1
    SOGA1 IER5 0 0 0 230 1 1
    SOGA1 HSD17B10 0 0 167 167 1 1
    SOGA1 MNX1 0 0 139 157 1 1
    SOGA1 NFIX 0 0 142 173 1 1
    SOGA1 ACAD9 0 0 205 205 1 1
    SOGA1 GPR155 0 0 456 776 1 1
    SOGA1 TUFM 0 0 213 213 1 1
    SOGA1 RPS6KB2 0 0 150 194 1 2
    SOGA1 AURKB 270 0 0 270 1 1
    SOGA1 ADIPOQ 0 0 703 703 1 1
    SOGA1 GGA1 0 0 171 171 1 1
    SOGA1 ZNF219 292 0 0 303 1 1
    SOGA1 ATG4A 0 0 310 498 1 2
    SOGA1 MLXIP 0 0 210 210 1 1
    SOGA1 IGSF3 0 0 244 361 1 1
    SOGA1 HCFC1 0 0 181 284 1 1
    SOGA1 ADIPOR1 0 0 151 150 1 1
    SOGA1 DRAM2 0 0 265 284 1 2
    SOGA1 ATXN10 0 0 125 314 1 1
    SOGA1 RIC1 0 0 293 310 1 1
    SOGA1 EXT2 0 0 164 163 1 1
    SOGA1 MLXIPL 0 0 125 157 1 1
    SOGA1 ATG16L2 0 0 210 220 1 2
    SOGA1 MAP1LC3C 0 0 167 167 1 2
    SOGA1 GPIHBP1 0 0 208 222 1 1
    SOGA1 TTC29 0 0 601 798 1 1
    SOGA1 SIRT7 270 0 0 270 1 1
    SOGA1 PFN3 0 0 328 328 1 1
    SOGA1 SEC31A 0 0 62 160 1 1
    SOGA1 CPEB4 0 0 209 220 1 1
    SOGA1 ATG9A 0 0 162 161 1 2
    SOGA1 NR1D2 0 0 155 172 1 1
    SOGA1 CRTC2 0 0 138 200 1 1
    SOGA1 ZNF622 0 0 303 303 1 1
    SOGA1 CLASP2 0 0 421 438 1 1
    SOGA1 NDUFB11 0 0 89 172 1 1
    SOGA1 ANLN 270 0 0 270 1 1
    SOGA1 ATP5O 0 0 166 165 1 1
    SOGA1 SBF1 0 0 212 212 1 1
    SOGA1 CD109 0 0 150 169 1 1
    SOGA1 ALG13 0 0 157 162 1 1
    SOGA1 ULK2 0 0 260 260 1 2
    SOGA1 ARHGEF10L 0 0 142 161 1 1
    SOGA1 C17orf85 0 0 241 240 1 1
    SOGA1 ELOVL4 0 0 163 163 1 1
    SOGA1 NAT8L 0 0 280 311 1 1
    SOGA1 EI24 0 0 232 248 1 2
    SOGA1 TCIRG1 0 0 170 169 1 1
    SOGA1 AGAP3 0 0 269 360 1 1
    SOGA1 PENK 0 0 145 163 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0051301 Biological Process cell division involved_in IEA
    GO:0007059 Biological Process chromosome segregation involved_in IMP
    GO:0008286 Biological Process insulin receptor signaling pathway involved_in IBA
    GO:0008286 Biological Process insulin receptor signaling pathway involved_in ISS
    GO:0045721 Biological Process negative regulation of gluconeogenesis involved_in ISS
    GO:0010506 Biological Process regulation of autophagy involved_in ISS
    GO:0000139 Cellular Component Golgi membrane located_in IEA
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005615 Cellular Component extracellular space is_active_in IBA
    GO:0005615 Cellular Component extracellular space located_in IDA
    GO:0005874 Cellular Component microtubule located_in IDA
    GO:0030496 Cellular Component midbody located_in IDA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_080627 4 mRNA transcript variant 1 NC_000020 Reference
    NM_199181 3 mRNA transcript variant 2 NC_000020 Reference