CAPN10

calpain 10
General Information
Name calpain 10
Alias
  • calpain-10
  • calcium-activated neutral proteinase 10
  • calpain-like protease CAPN10
Synonyms CANP10 NIDDM1
Gene_family Calpains
organism Homo sapiens
entrez_id 11132
location 2q37.3
transcript_count 2
exon_count 12
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010]
      Stringdb Calpain-10; Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake; Belongs to the peptidase C2 family
      nextProt Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    CAPN10 BioGRID KCTD7 GeneID BioGRID Affinity Capture-Western
    CAPN10 BioGRID CUL3 GeneID BioGRID Affinity Capture-Western
    CAPN10 BioGRID TUBB8 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID MISP GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID DOCK7 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID KCMF1 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID MAP1S GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID NME7 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID AHCYL2 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID UBR4 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID AHCYL1 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID CCT6B GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID CCT2 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID CCT4 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID CCT7 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID TUBA1A GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID ZMYM2 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID TCP1 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID STK4 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID STK3 GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID MAP1B GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID MAP1A GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID CCT6A GeneID BioGRID Affinity Capture-MS
    CAPN10 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    CAPN10 BioGRID SHD GeneID BioGRID Two-hybrid
    CAPN10 BioGRID EFNB1 GeneID BioGRID Two-hybrid
    CAPN10 BioGRID FLOT1 GeneID BioGRID Two-hybrid
    CAPN10 BioGRID PSMA7 GeneID BioGRID Two-hybrid
    CAPN10 BioGRID FANCC GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    CAPN10 GYS1 0 0 181 182 1 1
    CAPN10 CYB5R4 0 0 49 167 1 1
    CAPN10 MICU3 0 0 0 175 1 1
    CAPN10 CYP11A1 0 0 306 324 1 1
    CAPN10 CDKN2B 0 0 308 320 1 1
    CAPN10 RAB3D 0 0 76 167 1 1
    CAPN10 FRMD6 0 0 67 251 1 1
    CAPN10 ADGB 0 0 243 242 1 1
    CAPN10 SRD5A1 0 0 499 499 1 1
    CAPN10 KCNJ15 0 0 434 434 1 1
    CAPN10 PDIA3 0 0 0 171 1 1
    CAPN10 GNAI3 0 0 182 187 1 2
    CAPN10 GLIS3 0 0 211 256 1 1
    CAPN10 PPP1R3A 0 0 431 443 1 1
    CAPN10 CAPN9 0 0 469 508 1 1
    CAPN10 GK5 0 0 153 158 1 1
    CAPN10 LMAN2L 0 0 148 379 1 1
    CAPN10 MTMR9 0 0 113 155 1 1
    CAPN10 PDX1 0 0 280 280 1 1
    CAPN10 PON1 0 0 261 261 1 1
    CAPN10 TLN2 0 0 0 169 1 1
    CAPN10 CAPN8 0 0 211 363 1 1
    CAPN10 TTR 0 0 122 319 1 2
    CAPN10 CDKN2A 0 0 315 327 1 2
    CAPN10 KIF1C 0 0 0 365 1 1
    CAPN10 CHRND 0 0 108 246 1 1
    CAPN10 JAZF1 0 0 391 390 1 1
    CAPN10 PEPD 0 0 87 187 1 1
    CAPN10 PDIA4 0 0 0 171 1 1
    CAPN10 PRTFDC1 0 0 0 254 1 1
    CAPN10 CDC123 0 0 414 414 1 1
    CAPN10 CNDP1 0 0 95 188 1 1
    CAPN10 PSMG1 0 0 284 284 1 1
    CAPN10 SLC6A14 0 0 184 456 1 1
    CAPN10 CASP3 0 0 185 199 1 2
    CAPN10 ENPP1 0 0 519 519 1 1
    CAPN10 SULT1C2 0 0 0 299 1 1
    CAPN10 NOTCH2 0 0 181 181 1 1
    CAPN10 ACE 0 0 227 226 1 1
    CAPN10 HOXC10 0 0 73 170 1 1
    CAPN10 CACNA2D3 0 0 113 185 1 1
    CAPN10 RNPEP 0 0 740 740 1 1
    CAPN10 LRRC52 0 0 60 155 1 1
    CAPN10 RAB27B 0 0 0 189 1 1
    CAPN10 CAPN7 0 0 517 341 1 1
    CAPN10 GPD2 0 0 443 447 1 1
    CAPN10 LEP 0 0 268 268 1 1
    CAPN10 HFE 0 0 260 274 1 1
    CAPN10 HOXC11 0 0 74 214 1 1
    CAPN10 ZNRF1 0 0 53 234 1 1
    CAPN10 PRKAA2 0 0 244 255 1 2
    CAPN10 D2HGDH 0 0 134 320 1 1
    CAPN10 AGPS 0 0 0 152 1 1
    CAPN10 AMPD2 0 0 240 256 1 1
    CAPN10 GC 0 0 123 183 1 1
    CAPN10 TXN2 0 0 67 181 1 1
    CAPN10 PLBD1 0 0 138 201 1 1
    CAPN10 AMPD1 0 0 187 223 1 1
    CAPN10 PARVG 0 0 113 494 1 1
    CAPN10 HHEX 0 0 559 559 1 1
    CAPN10 ARVCF 0 0 0 199 1 1
    CAPN10 AGRP 0 0 166 303 1 1
    CAPN10 ZNF263 0 0 108 159 1 1
    CAPN10 HTR3D 0 0 150 275 1 1
    CAPN10 GAD2 0 0 96 332 1 1
    CAPN10 SERPINC1 0 0 63 207 1 1
    CAPN10 IGF2 0 0 181 181 1 1
    CAPN10 CHMP6 0 0 0 155 1 1
    CAPN10 GAREML 0 0 257 256 1 1
    CAPN10 NDUFB8 0 0 219 297 1 1
    CAPN10 TSPAN8 0 0 278 278 1 1
    CAPN10 HTR3C 0 0 0 183 1 1
    CAPN10 PTPN1 0 0 305 305 1 1
    CAPN10 TNFAIP2 0 0 0 156 1 1
    CAPN10 SRD5A2 0 0 396 396 1 1
    CAPN10 CAPNS1 0 600 502 834 1 2
    CAPN10 EXOC3L1 0 0 0 156 1 1
    CAPN10 ACBD3 0 0 0 153 1 1
    CAPN10 AVPR2 0 0 66 320 1 1
    CAPN10 TMED8 0 0 0 153 1 1
    CAPN10 ENSG00000100926 0 0 0 270 1 1
    CAPN10 ILDR2 0 0 49 151 1 1
    CAPN10 ABHD17A 0 0 0 176 1 1
    CAPN10 CHMP2A 0 0 0 153 1 2
    CAPN10 PDCD6IP 0 0 0 174 1 1
    CAPN10 ALDH7A1 0 0 68 176 1 1
    CAPN10 STRN3 0 0 0 213 1 1
    CAPN10 ADAMTS9 0 0 270 270 1 1
    CAPN10 LCT 0 0 0 212 1 1
    CAPN10 SNAP25 0 0 294 447 1 1
    CAPN10 STRN 0 0 0 213 1 1
    CAPN10 OR4C6 0 0 193 193 1 1
    CAPN10 EXOC3L2 0 0 45 160 1 1
    CAPN10 RETN 0 0 415 414 1 1
    CAPN10 RFPL4B 0 0 100 173 1 1
    CAPN10 CTNNBL1 0 0 0 268 1 1
    CAPN10 METTL13 0 0 0 151 1 1
    CAPN10 AGT 0 0 142 236 1 1
    CAPN10 GCG 0 0 224 300 1 1
    CAPN10 CAPN11 0 0 380 340 1 1
    CAPN10 FSHR 0 0 174 173 1 1
    CAPN10 PRKAA1 0 0 165 177 1 2
    CAPN10 OR13D1 0 0 211 211 1 1
    CAPN10 MTHFR 0 0 243 242 1 1
    CAPN10 TXNDC11 0 0 0 171 1 1
    CAPN10 ADRA2C 0 0 141 164 1 1
    CAPN10 ABHD17C 0 0 0 150 1 1
    CAPN10 IRS1 0 0 500 499 1 1
    CAPN10 HOXC6 0 0 57 201 1 1
    CAPN10 CHMP4B 0 0 0 268 1 2
    CAPN10 DEK 0 0 0 169 1 1
    CAPN10 IDE 0 0 260 276 1 1
    CAPN10 PCSK2 0 0 118 222 1 1
    CAPN10 CAST 0 0 594 776 1 1
    CAPN10 ENSG00000264813 0 0 220 220 1 1
    CAPN10 STXBP3 0 0 150 180 1 1
    CAPN10 HPRT1 0 0 0 175 1 1
    CAPN10 MICU2 0 0 0 175 1 1
    CAPN10 GPR35 0 0 739 739 1 1
    CAPN10 FEM1B 0 0 257 278 1 1
    CAPN10 CHRNG 0 0 96 190 1 1
    CAPN10 PSMA7 111 0 0 155 1 1
    CAPN10 HOXC12 0 0 95 261 1 1
    CAPN10 HSD17B2 0 0 75 274 1 1
    CAPN10 SNX19 0 0 91 166 1 1
    CAPN10 DHCR24 0 0 0 152 1 1
    CAPN10 MCIDAS 0 0 112 180 1 1
    CAPN10 CDKAL1 0 0 611 611 1 1
    CAPN10 MC4R 0 0 255 417 1 1
    CAPN10 UBA3 0 0 0 151 1 1
    CAPN10 CYP2C9 0 0 181 202 1 1
    CAPN10 H6PD 0 0 488 498 1 1
    CAPN10 MESDC1 0 0 0 169 1 1
    CAPN10 SORCS1 0 0 245 511 1 1
    CAPN10 CHMP4A 0 0 0 268 1 1
    CAPN10 ADIPOR2 0 0 189 205 1 1
    CAPN10 HNF4A 0 0 381 381 1 1
    CAPN10 RNPEPL1 0 0 764 773 1 1
    CAPN10 SLC30A8 0 0 563 563 1 1
    CAPN10 SCAF4 0 0 150 165 1 1
    CAPN10 EID2 0 0 358 358 1 1
    CAPN10 ZRANB2 0 0 209 209 1 1
    CAPN10 SLC2A4 0 0 348 616 1 1
    CAPN10 RABEP2 0 0 374 374 1 1
    CAPN10 APOE 0 0 155 154 1 1
    CAPN10 UBE2E2 0 0 164 193 1 1
    CAPN10 ZNF324B 0 0 517 545 1 1
    CAPN10 SHBG 0 0 234 243 1 1
    CAPN10 FEM1A 0 0 248 279 1 1
    CAPN10 FEM1C 0 0 233 255 1 1
    CAPN10 PTPN23 0 0 0 174 1 1
    CAPN10 MMP23B 0 0 88 184 1 1
    CAPN10 FAM208B 0 0 261 272 1 1
    CAPN10 MTNR1B 0 0 457 460 1 1
    CAPN10 R3HDML 0 0 150 168 1 1
    CAPN10 ASNS 0 0 0 165 1 1
    CAPN10 PARL 0 0 95 206 1 1
    CAPN10 WDR78 0 0 211 229 1 1
    CAPN10 ACACB 0 0 97 172 1 1
    CAPN10 GSTM1 0 0 160 159 1 1
    CAPN10 CPE 0 0 434 434 1 1
    CAPN10 UCKL1 0 0 138 170 1 1
    CAPN10 CYP21A2 0 0 181 314 1 1
    CAPN10 FBN3 0 0 539 539 1 1
    CAPN10 PPARG 0 0 564 589 1 1
    CAPN10 AKT1 0 0 160 192 1 2
    CAPN10 CAPN1 0 0 635 404 1 2
    CAPN10 CLPP 0 0 125 276 1 1
    CAPN10 EXOSC4 0 0 324 323 1 1
    CAPN10 ERICH3 0 0 180 268 1 1
    CAPN10 MOCS3 0 0 113 173 1 1
    CAPN10 DENND1A 0 0 283 282 1 1
    CAPN10 ECE2 0 0 0 242 1 1
    CAPN10 KIF1B 0 0 0 530 1 1
    CAPN10 RGS7 0 0 81 163 1 1
    CAPN10 SLC8A2 0 0 0 189 1 1
    CAPN10 PARD3B 0 0 113 150 1 1
    CAPN10 KL 0 0 0 183 1 1
    CAPN10 CYP19A1 0 0 432 468 1 1
    CAPN10 SHD 170 0 0 169 1 1
    CAPN10 KIF11 0 0 147 205 1 1
    CAPN10 CAPN2 0 0 601 386 1 2
    CAPN10 FST 0 0 324 323 1 1
    CAPN10 SHISA9 0 0 134 154 1 1
    CAPN10 IRS2 0 0 262 267 1 1
    CAPN10 CYB5B 0 0 0 175 1 1
    CAPN10 RAB27A 0 0 85 333 1 1
    CAPN10 CAMK1D 0 0 310 309 1 1
    CAPN10 SS18 0 0 68 278 1 1
    CAPN10 RBP4 0 0 142 170 1 1
    CAPN10 PPM1F 0 0 108 192 1 1
    CAPN10 ENSG00000249884 0 0 0 153 1 1
    CAPN10 INSR 0 0 323 334 1 1
    CAPN10 STX4 0 0 108 175 1 1
    CAPN10 ZYG11B 0 0 0 150 1 1
    CAPN10 ZER1 0 0 0 150 1 1
    CAPN10 PROSC 0 0 0 165 1 1
    CAPN10 LCTL 0 0 0 198 1 1
    CAPN10 PDIA2 0 0 0 171 1 1
    CAPN10 ZNF804A 0 0 108 472 1 1
    CAPN10 ABHD12B 0 0 66 254 1 1
    CAPN10 NEUROD1 0 0 389 388 1 1
    CAPN10 ASS1 0 0 0 156 1 1
    CAPN10 PAFAH2 0 0 150 199 1 1
    CAPN10 INS 0 0 564 564 1 1
    CAPN10 GLP1R 0 0 95 157 1 1
    CAPN10 EXOC3 0 0 0 156 1 1
    CAPN10 TRANK1 0 0 125 364 1 1
    CAPN10 PRLH 0 0 172 171 1 1
    CAPN10 CAPN12 0 0 458 189 1 1
    CAPN10 GIPR 0 0 96 193 1 1
    CAPN10 THADA 0 0 391 390 1 1
    CAPN10 CDK5 0 0 157 175 1 2
    CAPN10 AVPR1B 0 0 81 414 1 1
    CAPN10 ZMIZ1 0 0 261 278 1 1
    CAPN10 HNF1B 0 0 356 356 1 1
    CAPN10 CAPN6 0 0 518 430 1 1
    CAPN10 KIF16B 0 0 0 365 1 1
    CAPN10 SORCS3 0 0 0 259 1 1
    CAPN10 LEPR 0 0 152 237 1 1
    CAPN10 EIF4E2 0 0 95 192 1 1
    CAPN10 ADRB3 0 0 315 315 1 1
    CAPN10 NR3C2 0 0 0 192 1 1
    CAPN10 CYP3A4 0 0 113 190 1 1
    CAPN10 CHMP3 0 0 0 153 1 1
    CAPN10 ABCC8 0 0 465 476 1 1
    CAPN10 SOWAHD 0 0 0 211 1 1
    CAPN10 EXOC3L4 0 0 0 156 1 1
    CAPN10 CTH 0 0 0 263 1 1
    CAPN10 HYOU1 0 0 161 218 1 1
    CAPN10 BCL11A 0 0 170 336 1 1
    CAPN10 ADIPOQ 0 0 376 381 1 1
    CAPN10 CYP3A5 0 0 122 240 1 1
    CAPN10 RHPN2 0 0 0 174 1 1
    CAPN10 RPS27 0 0 0 171 1 1
    CAPN10 NR3C1 0 0 108 160 1 1
    CAPN10 MT-ND6 0 0 135 195 1 1
    CAPN10 ACAD10 0 0 138 197 1 1
    CAPN10 GCGR 0 0 112 152 1 1
    CAPN10 UBE4B 0 0 92 173 1 1
    CAPN10 HSPE1-MOB4 0 0 0 161 1 1
    CAPN10 PPARA 0 0 170 218 1 1
    CAPN10 ATP6V1D 0 0 0 248 1 1
    CAPN10 PPM1L 0 0 46 272 1 1
    CAPN10 HTR3E 0 0 0 183 1 1
    CAPN10 POMC 0 0 141 294 1 1
    CAPN10 PCSK1 0 0 386 391 1 1
    CAPN10 CXCL17 0 0 0 250 1 1
    CAPN10 HNF1A 0 0 308 307 1 1
    CAPN10 FARP2 0 0 210 210 1 1
    CAPN10 CYP27A1 0 0 0 161 1 1
    CAPN10 PRKAB2 0 0 170 169 1 1
    CAPN10 WDR64 0 0 0 213 1 1
    CAPN10 STRN4 0 0 0 213 1 1
    CAPN10 HGD 0 0 47 250 1 1
    CAPN10 P4HB 0 0 0 171 1 2
    CAPN10 ACACA 0 0 70 184 1 1
    CAPN10 MOB4 0 0 0 161 1 1
    CAPN10 MICU1 0 0 0 175 1 1
    CAPN10 RXFP2 0 0 81 249 1 1
    CAPN10 CAPN13 0 0 528 443 1 1
    CAPN10 KLB 0 0 0 183 1 1
    CAPN10 CHMP4C 0 0 0 268 1 1
    CAPN10 HOXC4 0 0 66 209 1 1
    CAPN10 TLN1 0 0 0 169 1 1
    CAPN10 WFS1 0 0 391 390 1 1
    CAPN10 PPARGC1A 0 0 189 189 1 1
    CAPN10 TNFRSF6B 0 0 164 163 1 1
    CAPN10 PCK1 0 0 234 251 1 1
    CAPN10 ADAM30 0 0 293 293 1 1
    CAPN10 FA2H 0 0 0 186 1 1
    CAPN10 CAPN3 0 0 564 535 1 1
    CAPN10 AKT2 0 0 306 326 1 1
    CAPN10 CAB39 0 0 126 257 1 1
    CAPN10 PAK7 0 0 0 169 1 1
    CAPN10 CYB5D1 0 0 0 175 1 1
    CAPN10 CYB5A 0 0 0 175 1 1
    CAPN10 CACNA1S 0 0 0 204 1 1
    CAPN10 SRI 0 0 74 260 1 1
    CAPN10 C2CD4A 0 0 211 211 1 1
    CAPN10 METTL12 0 0 0 151 1 1
    CAPN10 SLC2A2 0 0 357 386 1 1
    CAPN10 LMNA 45 0 72 170 1 1
    CAPN10 HOXC13 0 0 67 210 1 1
    CAPN10 VAMP4 0 0 92 161 1 1
    CAPN10 USP54 0 0 141 159 1 1
    CAPN10 PEF1 0 0 0 233 1 1
    CAPN10 CAPNS2 0 600 124 716 1 1
    CAPN10 ABHD17B 0 0 0 150 1 1
    CAPN10 ZYG11A 0 0 0 150 1 1
    CAPN10 SLC2A1 0 0 142 181 1 1
    CAPN10 LACTB 0 0 44 191 1 1
    CAPN10 RHPN1 0 0 0 194 1 1
    CAPN10 PTPN22 0 0 150 181 1 1
    CAPN10 HOXC5 0 0 103 240 1 1
    CAPN10 PDCD6 0 0 0 233 1 1
    CAPN10 MESDC2 0 0 0 158 1 1
    CAPN10 PAX4 0 0 357 357 1 1
    CAPN10 PCYT2 0 0 0 174 1 1
    CAPN10 CACNA1C 0 0 75 232 1 1
    CAPN10 VIPR2 0 0 57 221 1 1
    CAPN10 CYP4B1 0 0 74 206 1 1
    CAPN10 LDHD 0 0 126 228 1 1
    CAPN10 NAE1 0 0 0 155 1 1
    CAPN10 CAPN5 0 0 650 532 1 1
    CAPN10 ATP6V1H 0 0 95 300 1 1
    CAPN10 GCK 0 0 391 400 1 1
    CAPN10 MMP21 0 0 113 189 1 1
    CAPN10 KCNQ1 0 0 400 400 1 1
    CAPN10 SELENBP1 0 0 0 170 1 1
    CAPN10 CCDC124 0 0 218 218 1 1
    CAPN10 ABHD12 0 0 0 234 1 1
    CAPN10 EPHX2 0 0 405 418 1 1
    CAPN10 SUMO4 0 0 166 225 1 1
    CAPN10 UCP2 0 0 277 277 1 1
    CAPN10 CLK3 0 0 210 210 1 1
    CAPN10 TRA2A 0 0 73 326 1 1
    CAPN10 C5orf34 0 0 233 232 1 1
    CAPN10 SPNS1 0 0 135 167 1 2
    CAPN10 STAP2 0 0 0 167 1 1
    CAPN10 LYPLA1 0 0 77 247 1 1
    CAPN10 GCA 0 0 72 258 1 1
    CAPN10 SORT1 0 0 150 294 1 1
    CAPN10 MTMR3 0 0 324 323 1 2
    CAPN10 GPR1 0 0 539 539 1 1
    CAPN10 UPB1 0 0 46 259 1 1
    CAPN10 SPATA17 0 0 181 192 1 1
    CAPN10 RPS27L 0 0 0 171 1 1
    CAPN10 SULT2A1 0 0 537 537 1 1
    CAPN10 RYR3 0 0 141 203 1 1
    CAPN10 FTO 0 0 556 556 1 1
    CAPN10 KLK2 0 0 398 398 1 1
    CAPN10 GTF2A1L 0 0 193 193 1 1
    CAPN10 RGS20 0 0 109 352 1 1
    CAPN10 GCKR 0 0 157 156 1 1
    CAPN10 RYR2 0 0 229 256 1 1
    CAPN10 BCL11B 0 0 0 151 1 1
    CAPN10 KCNJ11 0 0 681 681 1 1
    CAPN10 CYP17A1 0 0 307 325 1 1
    CAPN10 PDLIM1 0 0 103 465 1 1
    CAPN10 HSD11B1 0 0 398 398 1 1
    CAPN10 LMAN2 0 0 0 206 1 1
    CAPN10 TENM4 0 0 92 339 1 1
    CAPN10 NDUFV2 0 0 325 478 1 1
    CAPN10 KIF1A 0 0 170 690 1 1
    CAPN10 TCF7L2 0 0 767 767 1 1
    CAPN10 CAPN15 0 0 518 385 1 1
    CAPN10 ZDHHC23 0 0 161 161 1 1
    CAPN10 IGF2BP2 0 0 601 601 1 1
    CAPN10 KCNIP4 0 0 235 250 1 1
    CAPN10 C7orf31 0 0 374 374 1 1
    CAPN10 FAM24A 0 0 393 392 1 1
    CAPN10 CLCN2 0 0 162 173 1 1
    CAPN10 ENSG00000026036 0 0 164 194 1 1
    CAPN10 MAPK8IP1 0 0 390 390 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0000149 Molecular Function SNARE binding enables ISS
    GO:0004198 Molecular Function calcium-dependent cysteine-type endopeptidase activity enables IBA
    GO:0004198 Molecular Function calcium-dependent cysteine-type endopeptidase activity enables IMP
    GO:0008092 Molecular Function cytoskeletal protein binding enables ISS
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0006921 Biological Process cellular component disassembly involved in execution phase of apoptosis involved_in IC
    GO:0032869 Biological Process cellular response to insulin stimulus involved_in IMP
    GO:0046326 Biological Process positive regulation of D-glucose import involved_in IMP
    GO:0032024 Biological Process positive regulation of insulin secretion involved_in IMP
    GO:0032388 Biological Process positive regulation of intracellular transport involved_in ISS
    GO:2000676 Biological Process positive regulation of type B pancreatic cell apoptotic process involved_in IEA
    GO:0006508 Biological Process proteolysis involved_in IBA
    GO:0006508 Biological Process proteolysis involved_in IMP
    GO:0032956 Biological Process regulation of actin cytoskeleton organization involved_in ISS
    GO:0097050 Biological Process type B pancreatic cell apoptotic process involved_in IDA
    GO:0005737 Cellular Component cytoplasm is_active_in IBA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in ISS
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0005886 Cellular Component plasma membrane located_in ISS
    Pathways
    Name DB ID
    Degradation of the extracellular matrix Reactome R-HSA-1474228
    Extracellular matrix organization Reactome R-HSA-1474244
    Integrin-mediated cell adhesion (WP185) WikiPathways WP185_r116785
    2q37 copy number variation syndrome (WP5224) WikiPathways WP5224_r122740
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_023083 4 mRNA transcript variant 1 NC_000002 Reference
    NM_023085 4 mRNA transcript variant 3 NC_000002 Reference