DEPP1

DEPP autophagy regulator 1
General Information
Name DEPP autophagy regulator 1
Alias
  • protein DEPP1
  • decidual protein induced by progesterone
  • fasting induced
  • fasting-induced gene protein
  • fasting-induced protein
  • fat-specific expressed
  • protein DEPP
Synonyms DEPP FIG Fseg C10orf10
Gene_family None
organism Homo sapiens
entrez_id 11067
location 10q11.21
transcript_count 1
exon_count 2
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and activation of the transcription factor ELK1. [provided by RefSeq, Jul 2008]
      nextProt Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    DEPP1 BioGRID EGFR GeneID BioGRID Negative Genetic
    DEPP1 BioGRID TRIM23 GeneID BioGRID Two-hybrid
    DEPP1 BioGRID QKI GeneID BioGRID Two-hybrid
    DEPP1 Protein USHBP1 GeneID HPRD None
    DEPP1 Protein CCDC85B GeneID HPRD None
    DEPP1 Protein PLSCR1 GeneID HPRD None
    DEPP1 Protein QKI GeneID HPRD None
    DEPP1 Protein KRT15 GeneID HPRD None
    DEPP1 Protein KRT19 GeneID HPRD None
    DEPP1 BioGRID USHBP1 GeneID BioGRID Two-hybrid
    DEPP1 BioGRID CCDC85B GeneID BioGRID Two-hybrid
    DEPP1 BioGRID PLSCR1 GeneID BioGRID Two-hybrid
    DEPP1 BioGRID KRT19 GeneID BioGRID Two-hybrid
    DEPP1 BioGRID KRT15 GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    C10orf10 FOXO3 0 0 264 264 2 1
    C10orf10 MCL1 0 0 75 173 2 1
    C10orf10 BCL2L1 0 0 108 169 2 1
    C10orf10 FOXO1 0 0 233 237 2 1
    C10orf10 PPP1R15A 0 0 60 204 2 1
    C10orf10 TRIM17 0 0 100 331 2 1
    C10orf10 SESN1 0 0 81 226 2 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0006914 Biological Process autophagy involved_in IEA
    GO:0010506 Biological Process regulation of autophagy involved_in IBA
    GO:0010506 Biological Process regulation of autophagy involved_in IDA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
    GO:0005739 Cellular Component mitochondrion is_active_in IBA
    GO:0005739 Cellular Component mitochondrion located_in IDA
    GO:0005777 Cellular Component peroxisome located_in IDA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_007021 4 mRNA None NC_000010 Reference