CDKN2B-AS1

CDKN2B antisense RNA 1
General Information
Name CDKN2B antisense RNA 1
Alias
  • CDKN2B antisense RNA 1 (non-protein coding)
  • antisense noncoding RNA in the INK4 locus
  • p15 antisense RNA
  • prostate cancer associated transcript 12
Synonyms ANRIL RP11-145E5.4 NCRNA00089 p15AS CDKN2B-AS PCAT12 CDKN2BAS
Gene_family Antisense RNAs
organism Homo sapiens
entrez_id 100048912
location 9p21.3
transcript_count 32
exon_count 22
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene is located within the CDKN2B-CDKN2A gene cluster at chromosome 9p21. The gene product is a functional RNA molecule that interacts with polycomb repressive complex-1 (PRC1) and -2 (PRC2), leading to epigenetic silencing of other genes in this cluster. This region is a significant genetic susceptibility locus for cardiovascular disease, and has also been linked to a number of other pathologies, including several cancers, intracranial aneurysm, type-2 diabetes, periodontitis, Alzheimer's disease, endometriosis, frailty in the elderly, and glaucoma. Multiple alternatively processed transcript variants have been detected, some of which may take the form of circular RNA molecules (PMID:21151960). [provided by RefSeq, May 2014]
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    CDKN2B-AS1 BioGRID WDR5 GeneID BioGRID Affinity Capture-RNA
    CDKN2B-AS1 BioGRID HDAC3 GeneID BioGRID Affinity Capture-RNA
    CDKN2B-AS1 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    CDKN2B-AS1 BioGRID EZH2 GeneID BioGRID Protein-RNA
    StringDB
    A B experiments database textmining combined score hadb nhadb
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0031507 Biological Process heterochromatin formation involved_in IEA
    Pathways
    Name DB ID
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NR_185867 1 ncRNA transcript variant 32 NC_000009 Reference
    NR_185859 1 ncRNA transcript variant 24 NC_000009 Reference
    NR_120536 1 ncRNA transcript variant 14 NC_000009 Reference
    NR_003529 4 ncRNA transcript variant 1 NC_000009 Reference
    NR_047532 2 ncRNA transcript variant 2 NC_000009 Reference
    NR_185863 1 ncRNA transcript variant 28 NC_000009 Reference
    NR_185851 1 ncRNA transcript variant 16 NC_000009 Reference
    NR_185866 1 ncRNA transcript variant 31 NC_000009 Reference
    NR_185865 1 ncRNA transcript variant 30 NC_000009 Reference
    NR_185854 1 ncRNA transcript variant 19 NC_000009 Reference
    NR_185862 1 ncRNA transcript variant 27 NC_000009 Reference
    NR_185853 1 ncRNA transcript variant 18 NC_000009 Reference
    NR_185860 1 ncRNA transcript variant 25 NC_000009 Reference
    NR_185864 1 ncRNA transcript variant 29 NC_000009 Reference
    NR_185855 1 ncRNA transcript variant 20 NC_000009 Reference
    NR_185850 1 ncRNA transcript variant 15 NC_000009 Reference
    NR_047543 2 ncRNA transcript variant 3 NC_000009 Reference
    NR_047535 2 ncRNA transcript variant 5 NC_000009 Reference
    NR_047537 2 ncRNA transcript variant 7 NC_000009 Reference
    NR_047534 2 ncRNA transcript variant 4 NC_000009 Reference
    NR_047536 2 ncRNA transcript variant 6 NC_000009 Reference
    NR_047538 2 ncRNA transcript variant 8 NC_000009 Reference
    NR_047539 2 ncRNA transcript variant 9 NC_000009 Reference
    NR_047540 2 ncRNA transcript variant 10 NC_000009 Reference
    NR_047541 2 ncRNA transcript variant 11 NC_000009 Reference
    NR_047542 2 ncRNA transcript variant 12 NC_000009 Reference
    NR_047533 2 ncRNA transcript variant 13 NC_000009 Reference
    NR_185857 1 ncRNA transcript variant 22 NC_000009 Reference
    NR_185856 1 ncRNA transcript variant 21 NC_000009 Reference
    NR_185852 1 ncRNA transcript variant 17 NC_000009 Reference
    NR_185858 1 ncRNA transcript variant 23 NC_000009 Reference
    NR_185861 1 ncRNA transcript variant 26 NC_000009 Reference