| (MAP1LC3C) microtubule-associated protein 1 light chain 3 gamma [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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282
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Official symbol
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MAP1LC3C
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Official name
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microtubule-associated protein 1 light chain 3 gamma
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 1 (NC_000001.10) : 242158791...242162384 (-)
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Map
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1q43
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Length
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3594 nt
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NM_001004343.2
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MAP1LC3C, mRNA isoform 1
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Accession
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Name
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Organism
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Length
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Q9BXW4
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Microtubule-associated proteins 1A/1B light chain 3C
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Homo sapiens
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147 aa
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| Synonyms |
LC3C
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| Alternative name(s) |
LC3-like protein 2; MAP1 light chain 3-like protein 2
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| Summary |
Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is 1 of 3 orthologs of the yeast autophagosome protein Atg8 (He et al., 2003 [PubMed 12740394]).[supplied by OMIM].
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Related Articles in PubMed
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Go to ensembl 
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| 1 |
GAGGAATGAG |
TTAGGTTCCC |
GGTTGCGGGA |
CAGTTTTTTT |
TTCTTTTTTA |
AAACAGACAC |
AGCTACTGAG |
TGCAATGCCG |
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| 81 |
CCTCCACAGA |
AAATCCCAAG |
CGTCAGACCC |
TTCAAGCAGA |
GGAAAAGCTT |
GGGTAAATTT |
CTTGGGGTAG |
CTTTCTGGGT |
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| 161 |
TATCTAAAGA |
GAGGAGCGGA |
TCTGGCCTTC |
TCTTGATCTT |
TGCTTCTTTT |
CTTGATCTTT |
GCTTCTTCTC |
TTGTGCTTGA |
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| 241 |
AATATTCACA |
GCAATCAGAC |
AAGAGGAAGT |
TGCTGGAATC |
CGGGCAAAGT |
TCCCCAACAA |
AATCCCGGTA |
AGACACCACT |
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| 321 |
GGACTTCCGC |
TGGGGGGCGT |
GGGGGTGGGG |
TTCCGATCCT |
GTTCTCTGAA |
AAACCAAGAG |
CAGCCAACAG |
CTTCCCTCTG |
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| 401 |
TCTGTTCCAA |
GTTCCTAACA |
CTCACGCTGA |
GTCACATTCT |
TAAGGACTGA |
CACTCTTGAC |
AGGTGGTAGT |
GGAGCGCTAC |
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| 481 |
CCCAGGGAGA |
CGTTCCTGCC |
CCCGCTGGAC |
AAAACCAAGT |
TCCTGGTCCC |
GCAGGAGCTG |
ACCATGACCC |
AGTTCCTCAG |
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| 561 |
CATCATCCGG |
TAGGTGGCGC |
AGAGCGTGCC |
CCGGAGGAAG |
GTGCGCTGGG |
TGCGCCGGGG |
CTGTTGGGCT |
TTCTTCGTTT |
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| 641 |
GGCAGTTTTA |
TTTTGGGGAT |
GGGGGCACGT |
CAGGGGAAGA |
GAGGAAAGAG |
ATTTTTTTGA |
AGTCACCTTT |
TAGATTCACT |
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| 721 |
AGTACCCTGA |
AAAGATGCTC |
TTAGAATTAC |
TCTATTTTAA |
ACCCCGGGCG |
GAGTGGCTCA |
TGCCTGTAAT |
CCCAGCACTC |
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| 801 |
TGGGAGGCTG |
AGGCAGGTGG |
ATCGCAGAGG |
TCAGGAGTTT |
GAGACCAGCC |
TGGCCAACGT |
GGTGAAACCC |
TGTCTCTACT |
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| 881 |
AAAAATACAA |
AAATTAGCTA |
GGCGTGGTGG |
CGGGTGCCTG |
TAATCCTAGC |
TACTTGGGAG |
GCTGAGGCAG |
GAGAATCGCT |
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| 961 |
TGAACCTGGG |
AGGCGGAGGT |
TACAGTGAGC |
CGAGACTGTT |
CCACTGCACT |
CCTGGGCAAC |
AAGAGTGAAA |
CTCTGTCTCA |
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| 1041 |
AAAAAAAAAA |
AAAAAAAAAA |
AGAATTACTC |
TATTTTAAAC |
AGGTAAGGAG |
AATCCCTCAG |
ACAACGACAA |
CAACAAAAAA |
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| 1121 |
GACCTGCCAA |
CATTTCTAAG |
AATTTCCTAA |
AGTAGTTAGT |
CTTGGCTCTC |
AAGCTAGGCC |
GGGAGATCCT |
TTCTTTCAGA |
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| 1201 |
TCTTGTGTGA |
AACCGAGTCT |
GCGCGTCCGT |
TGCAGAGACC |
AGCACCTTTT |
CCAAGTGTAT |
GTGTGCCTAG |
GGGTGGGGAC |
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| 1281 |
TTCTCCCCAA |
AGGAAACGTT |
CCCTGCTCAG |
AACACTGAGA |
GAGAAAAGCA |
TCCCCCAAAC |
ACACTCCTCC |
CTTGGTTAAG |
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| 1361 |
CCAGAGGTAC |
AGCAAAGAAC |
AGGCAGCTAT |
TCTTAAAGCA |
TAAAGGACAT |
CACTTGACAC |
ATGGATTCAG |
TAAAAAATGA |
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| 1441 |
TTTGGGAGTA |
AAGTAAATAT |
ACCCGATGAG |
TAAGTTTTCA |
ACAGGGTTGA |
AAAGTGCTTG |
GAAGCTGCAT |
CGCTGTTGCA |
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| 1521 |
GCCTGTTTTT |
TTGAGAACAC |
ACGATGAATG |
AGTGTCTTTT |
TATTTTGCTT |
TATTTAGCTC |
TGTCGCCTAG |
GCTGGAGTGC |
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| 1601 |
AGTGGTGTGA |
ACCTAGTTCA |
CTGCAGCCTT |
GGCCTTCTGG |
GCTCAGGCGA |
TCCTCCCATC |
TCAGCCTCCT |
GAGTAGCTGG |
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| 1681 |
GACTACAGGA |
AAGCACCACC |
GTGCCCGGCT |
AATTTTAAAA |
ATGTTCTGTA |
GAGATGGGGG |
TCTCACGATG |
TTGCCCAGGC |
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| 1761 |
CTCTTTTTAT |
TTTGTTTTAC |
TGAGTTAAGA |
GCATTCTGAT |
TTCCTCTCTC |
TAGGCAAACT |
TACATGTTAA |
AGTTAGTTCA |
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| 1841 |
GTGTGAATGG |
AAGATGGCCA |
AGGGAGAATG |
AAAGTTAGGA |
TTAGGGCCAG |
GCGCAGTGGC |
TCACACTGTA |
ATCCCAGCAC |
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| 1921 |
TTTGGGAAGC |
CAAGGCAGGG |
CAGATTACCT |
GAGGTCAGGA |
GTTCAAGAGC |
AGCCTGGCCA |
ACATGGCAAA |
ACCCCGTCTC |
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| 2001 |
TACTAAAAAT |
ACAAAAATTA |
CCCAGGTGTG |
GTGTTGCGTG |
CCTGTCATCC |
CAGCTACTTG |
GGAGGTTGAG |
GCAGGGGAAT |
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| 2081 |
CAAAAAAAAA |
AAGTGAAATA |
TCAGCGAGAC |
TGTGCATCAC |
CTTTGTACTT |
CTAGGGAAAT |
AGCTTTAATT |
TCTTTTCTTT |
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| 2161 |
TTTTTTTTTT |
TTTGAGACGC |
AGTCTTGCTC |
TGTCACCAGG |
CTGGAGTACA |
GTGGCGCAAT |
TTCGGCTCAC |
TGCAACCTCC |
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| 2241 |
GCCTCCTGGT |
TCTCCTGCCT |
CAGCCTCCCG |
AGTAGCTGGG |
ACTACAGGTT |
CACGCCACCA |
CACCCAGCTA |
ATTTTTGTAT |
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| 2321 |
TTTTAGTACA |
GACCAGGTTT |
CACCATGTTG |
GCCAGGATGG |
CCTCGATTTC |
TTGACCTCGT |
GAGCTGCCTG |
CCTCAGCTTC |
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| 2401 |
CCAAAGTGCT |
GGGATTAGAG |
GTGTGAGCCA |
CTGCATCCAG |
CCCAATAGCT |
TTAATTTCAT |
AGCAAATGGA |
AGTTATTTGC |
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| 2481 |
TTAGCATTTT |
TGTGTTGTCA |
TGTTTCCTCA |
ACCTGTTTGT |
GTTGTCATAT |
TTCATCCATG |
GAATGGCCTC |
ACCCTTTTGA |
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| 2561 |
CCCAAATGGG |
AAGCCTTGTA |
GTTCCTAAAT |
CTCAGGGAAG |
AAGAAGGGAG |
CAATTCAGTC |
TTCTTGAGTG |
TCATGAGGCT |
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| 2641 |
GCAGATCCCT |
GGGCTGTCTC |
GCAGGCCATA |
CCCTCACCAC |
CCTCCTGCCC |
ATCCCAGGAG |
CCGCATGGTC |
CTGAGAGCCA |
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| 2721 |
CGGAAGCCTT |
TTACTTGCTG |
GTGAACAACA |
AGAGCCTGGT |
CAGCATGAGC |
GCAACCATGG |
CAGAGATCTA |
CAGAGACTAC |
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| 2801 |
AAGGATGAGG |
ATGGCTTCGT |
GTACATGACC |
TACGCCTCCC |
AGGAGACATT |
TGGCTGCCTG |
GAGTCAGCAG |
CCCCCAGGGA |
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| 2881 |
TGGGAGCAGC |
CTTGAGGACA |
GACCCTGCAA |
TCCTCTCTAG |
CCCATGTCGG |
GAAGGATGTG |
TGCTCTGACA |
GACGTGTCAG |
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| 2961 |
ATGCTGGCAG |
AAGGGATTGG |
TTTTCTCCTG |
TGTATACAGT |
GGAGGAGTCT |
GAGAAGCAGG |
GATGCCTGGG |
GTGATCAGCT |
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| 3041 |
CCAACCAGTG |
GCAGCAGAGT |
GGTGGCTCTT |
CCTAGTTTAG |
TTTTTGTGCT |
CCGTGTTCTT |
GTGTCCTTCT |
AAGAAAAATG |
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| 3121 |
TGGGCTGCTC |
TTGAAAGTTA |
TATAATTATC |
ATTTTTTTTT |
TTTTGAAACA |
GGGTCTTGCT |
CTATTGCCTA |
GGCTGGAGCA |
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| 3201 |
CAGTGGCATG |
ATCTTGGCTC |
ACTGCAACCT |
CCGCCTCCTG |
GGTTCAAGTG |
ATTCTTCTGC |
CTCCACCCCC |
CGAGTGGCTG |
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| 3281 |
GTATTACAAG |
CACATGCCAC |
CACACCAGGC |
TAATTTTTGT |
ATTTTTAGTA |
GAGACGGGGT |
TTCACCATGT |
TGGCCAGGCT |
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| 3361 |
GGTCTCGAAC |
TCCTGACCTC |
AGGTGATCCA |
CCCACCTCGG |
CCTCCCAAAG |
TGCTGGGATT |
ACAGGCGTGA |
GCCACTGCAT |
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| 3441 |
CCAGCCATAT |
AACCGTATTC |
TAAATAAGAA |
ATGGTTGGCT |
TGTGTGATGG |
TTTTGTGTAA |
TGAGCTAGAG |
ATAATATTTT |
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| 3521 |
AAGTGTCTTC |
TGTGGTATAT |
GTGGGAGGGC |
CATTAAGGAG |
TGGGTTTCAC |
TCCCTGCATG |
TGGGCAGGTG |
TCCC |
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>ref|Gene_ID:440738|MAP1LC3C|NC_000001.10:242158791...242162384 (-)
GAGGAATGAGTTAGGTTCCCGGTTGCGGGACAGTTTTTTTTTCTTTTTTAAAACAGACACAGCTACTGAGTGCAATGCCG
CCTCCACAGAAAATCCCAAGCGTCAGACCCTTCAAGCAGAGGAAAAGCTTGGGTAAATTTCTTGGGGTAGCTTTCTGGGT
TATCTAAAGAGAGGAGCGGATCTGGCCTTCTCTTGATCTTTGCTTCTTTTCTTGATCTTTGCTTCTTCTCTTGTGCTTGA
AATATTCACAGCAATCAGACAAGAGGAAGTTGCTGGAATCCGGGCAAAGTTCCCCAACAAAATCCCGGTAAGACACCACT
GGACTTCCGCTGGGGGGCGTGGGGGTGGGGTTCCGATCCTGTTCTCTGAAAAACCAAGAGCAGCCAACAGCTTCCCTCTG
TCTGTTCCAAGTTCCTAACACTCACGCTGAGTCACATTCTTAAGGACTGACACTCTTGACAGGTGGTAGTGGAGCGCTAC
CCCAGGGAGACGTTCCTGCCCCCGCTGGACAAAACCAAGTTCCTGGTCCCGCAGGAGCTGACCATGACCCAGTTCCTCAG
CATCATCCGGTAGGTGGCGCAGAGCGTGCCCCGGAGGAAGGTGCGCTGGGTGCGCCGGGGCTGTTGGGCTTTCTTCGTTT
GGCAGTTTTATTTTGGGGATGGGGGCACGTCAGGGGAAGAGAGGAAAGAGATTTTTTTGAAGTCACCTTTTAGATTCACT
AGTACCCTGAAAAGATGCTCTTAGAATTACTCTATTTTAAACCCCGGGCGGAGTGGCTCATGCCTGTAATCCCAGCACTC
TGGGAGGCTGAGGCAGGTGGATCGCAGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTCTCTACT
AAAAATACAAAAATTAGCTAGGCGTGGTGGCGGGTGCCTGTAATCCTAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCT
TGAACCTGGGAGGCGGAGGTTACAGTGAGCCGAGACTGTTCCACTGCACTCCTGGGCAACAAGAGTGAAACTCTGTCTCA
AAAAAAAAAAAAAAAAAAAAAGAATTACTCTATTTTAAACAGGTAAGGAGAATCCCTCAGACAACGACAACAACAAAAAA
GACCTGCCAACATTTCTAAGAATTTCCTAAAGTAGTTAGTCTTGGCTCTCAAGCTAGGCCGGGAGATCCTTTCTTTCAGA
TCTTGTGTGAAACCGAGTCTGCGCGTCCGTTGCAGAGACCAGCACCTTTTCCAAGTGTATGTGTGCCTAGGGGTGGGGAC
TTCTCCCCAAAGGAAACGTTCCCTGCTCAGAACACTGAGAGAGAAAAGCATCCCCCAAACACACTCCTCCCTTGGTTAAG
CCAGAGGTACAGCAAAGAACAGGCAGCTATTCTTAAAGCATAAAGGACATCACTTGACACATGGATTCAGTAAAAAATGA
TTTGGGAGTAAAGTAAATATACCCGATGAGTAAGTTTTCAACAGGGTTGAAAAGTGCTTGGAAGCTGCATCGCTGTTGCA
GCCTGTTTTTTTGAGAACACACGATGAATGAGTGTCTTTTTATTTTGCTTTATTTAGCTCTGTCGCCTAGGCTGGAGTGC
AGTGGTGTGAACCTAGTTCACTGCAGCCTTGGCCTTCTGGGCTCAGGCGATCCTCCCATCTCAGCCTCCTGAGTAGCTGG
GACTACAGGAAAGCACCACCGTGCCCGGCTAATTTTAAAAATGTTCTGTAGAGATGGGGGTCTCACGATGTTGCCCAGGC
CTCTTTTTATTTTGTTTTACTGAGTTAAGAGCATTCTGATTTCCTCTCTCTAGGCAAACTTACATGTTAAAGTTAGTTCA
GTGTGAATGGAAGATGGCCAAGGGAGAATGAAAGTTAGGATTAGGGCCAGGCGCAGTGGCTCACACTGTAATCCCAGCAC
TTTGGGAAGCCAAGGCAGGGCAGATTACCTGAGGTCAGGAGTTCAAGAGCAGCCTGGCCAACATGGCAAAACCCCGTCTC
TACTAAAAATACAAAAATTACCCAGGTGTGGTGTTGCGTGCCTGTCATCCCAGCTACTTGGGAGGTTGAGGCAGGGGAAT
CAAAAAAAAAAAGTGAAATATCAGCGAGACTGTGCATCACCTTTGTACTTCTAGGGAAATAGCTTTAATTTCTTTTCTTT
TTTTTTTTTTTTTGAGACGCAGTCTTGCTCTGTCACCAGGCTGGAGTACAGTGGCGCAATTTCGGCTCACTGCAACCTCC
GCCTCCTGGTTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTTCACGCCACCACACCCAGCTAATTTTTGTAT
TTTTAGTACAGACCAGGTTTCACCATGTTGGCCAGGATGGCCTCGATTTCTTGACCTCGTGAGCTGCCTGCCTCAGCTTC
CCAAAGTGCTGGGATTAGAGGTGTGAGCCACTGCATCCAGCCCAATAGCTTTAATTTCATAGCAAATGGAAGTTATTTGC
TTAGCATTTTTGTGTTGTCATGTTTCCTCAACCTGTTTGTGTTGTCATATTTCATCCATGGAATGGCCTCACCCTTTTGA
CCCAAATGGGAAGCCTTGTAGTTCCTAAATCTCAGGGAAGAAGAAGGGAGCAATTCAGTCTTCTTGAGTGTCATGAGGCT
GCAGATCCCTGGGCTGTCTCGCAGGCCATACCCTCACCACCCTCCTGCCCATCCCAGGAGCCGCATGGTCCTGAGAGCCA
CGGAAGCCTTTTACTTGCTGGTGAACAACAAGAGCCTGGTCAGCATGAGCGCAACCATGGCAGAGATCTACAGAGACTAC
AAGGATGAGGATGGCTTCGTGTACATGACCTACGCCTCCCAGGAGACATTTGGCTGCCTGGAGTCAGCAGCCCCCAGGGA
TGGGAGCAGCCTTGAGGACAGACCCTGCAATCCTCTCTAGCCCATGTCGGGAAGGATGTGTGCTCTGACAGACGTGTCAG
ATGCTGGCAGAAGGGATTGGTTTTCTCCTGTGTATACAGTGGAGGAGTCTGAGAAGCAGGGATGCCTGGGGTGATCAGCT
CCAACCAGTGGCAGCAGAGTGGTGGCTCTTCCTAGTTTAGTTTTTGTGCTCCGTGTTCTTGTGTCCTTCTAAGAAAAATG
TGGGCTGCTCTTGAAAGTTATATAATTATCATTTTTTTTTTTTTGAAACAGGGTCTTGCTCTATTGCCTAGGCTGGAGCA
CAGTGGCATGATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTTCTGCCTCCACCCCCCGAGTGGCTG
GTATTACAAGCACATGCCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCT
GGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCAT
CCAGCCATATAACCGTATTCTAAATAAGAAATGGTTGGCTTGTGTGATGGTTTTGTGTAATGAGCTAGAGATAATATTTT
AAGTGTCTTCTGTGGTATATGTGGGAGGGCCATTAAGGAGTGGGTTTCACTCCCTGCATGTGGGCAGGTGTCCC
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| Primary source |
RefSeq : NM_001004343.2 (GI:211938456)
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| Name |
Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C)
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| Type of transcript |
mRNA
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| Organism |
Homo sapiens
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| Length |
1192 nt
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| Map |
1q43
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| Location |
Chromosome 1 (NC_000001.10) strand : -
| 242158791...242159686 | 242161815...242161921 | 242162077...242162132 | 242162252...242162384 |
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| Exon(s) |
Start |
End |
Length |
is coding |
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Exon 1
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1
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133
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133
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1
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Exon 2
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134
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189
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56
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1
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Exon 3
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190
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296
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107
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1
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Exon 4
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297
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1192
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896
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1
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| ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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| Primary source |
NCBI : CCDS31074
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| Nucleotide |
MAP1LC3C, mRNA isoform 1[NM_001004343.2] : 76...519
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| Length |
444
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| Location |
Chromosome 1 (NC_000001.10) strand : -
| 242159464...242159686 | 242161815...242161921 | 242162077...242162132 | 242162252...242162309 |
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| Start codon |
1
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| Translation |
NP_001004343.1 |
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| 1 |
GGAGGAATGA |
GTTAGGTTCC |
CGGTTGCGGG |
ACAGTTTTTT |
TTTCTTTTTT |
AAAACAGACA |
CAGCTACTGA |
GTGCAATGCC |
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| 81 |
GCCTCCACAG |
AAAATCCCAA |
GCGTCAGACC |
CTTCAAGCAG |
AGGAAAAGCT |
TGGCAATCAG |
ACAAGAGGAA |
GTTGCTGGAA |
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| 161 |
TCCGGGCAAA |
GTTCCCCAAC |
AAAATCCCGG |
TGGTAGTGGA |
GCGCTACCCC |
AGGGAGACGT |
TCCTGCCCCC |
GCTGGACAAA |
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| 241 |
ACCAAGTTCC |
TGGTCCCGCA |
GGAGCTGACC |
ATGACCCAGT |
TCCTCAGCAT |
CATCCGGAGC |
CGCATGGTCC |
TGAGAGCCAC |
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| 321 |
GGAAGCCTTT |
TACTTGCTGG |
TGAACAACAA |
GAGCCTGGTC |
AGCATGAGCG |
CAACCATGGC |
AGAGATCTAC |
AGAGACTACA |
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| 401 |
AGGATGAGGA |
TGGCTTCGTG |
TACATGACCT |
ACGCCTCCCA |
GGAGACATTT |
GGCTGCCTGG |
AGTCAGCAGC |
CCCCAGGGAT |
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| 481 |
GGGAGCAGCC |
TTGAGGACAG |
ACCCTGCAAT |
CCTCTCTAGC |
CCATGTCGGG |
AAGGATGTGT |
GCTCTGACAG |
ACGTGTCAGA |
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| 561 |
TGCTGGCAGA |
AGGGATTGGT |
TTTCTCCTGT |
GTATACAGTG |
GAGGAGTCTG |
AGAAGCAGGG |
ATGCCTGGGG |
TGATCAGCTC |
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| 641 |
CAACCAGTGG |
CAGCAGAGTG |
GTGGCTCTTC |
CTAGTTTAGT |
TTTTGTGCTC |
CGTGTTCTTG |
TGTCCTTCTA |
AGAAAAATGT |
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| 721 |
GGGCTGCTCT |
TGAAAGTTAT |
ATAATTATCA |
TTTTTTTTTT |
TTTGAAACAG |
GGTCTTGCTC |
TATTGCCTAG |
GCTGGAGCAC |
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| 801 |
AGTGGCATGA |
TCTTGGCTCA |
CTGCAACCTC |
CGCCTCCTGG |
GTTCAAGTGA |
TTCTTCTGCC |
TCCACCCCCC |
GAGTGGCTGG |
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| 881 |
TATTACAAGC |
ACATGCCACC |
ACACCAGGCT |
AATTTTTGTA |
TTTTTAGTAG |
AGACGGGGTT |
TCACCATGTT |
GGCCAGGCTG |
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| 961 |
GTCTCGAACT |
CCTGACCTCA |
GGTGATCCAC |
CCACCTCGGC |
CTCCCAAAGT |
GCTGGGATTA |
CAGGCGTGAG |
CCACTGCATC |
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| 1041 |
CAGCCATATA |
ACCGTATTCT |
AAATAAGAAA |
TGGTTGGCTT |
GTGTGATGGT |
TTTGTGTAAT |
GAGCTAGAGA |
TAATATTTTA |
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| 1121 |
AGTGTCTTCT |
GTGGTATATG |
TGGGAGGGCC |
ATTAAGGAGT |
GGGTTTCACT |
CCCTGCATGT |
GGGCAGGTGT |
CC |
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>gi|211938456|ref|NM_001004343.2|Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C)
GGAGGAATGAGTTAGGTTCCCGGTTGCGGGACAGTTTTTTTTTCTTTTTTAAAACAGACACAGCTACTGAGTGCAATGCC
GCCTCCACAGAAAATCCCAAGCGTCAGACCCTTCAAGCAGAGGAAAAGCTTGGCAATCAGACAAGAGGAAGTTGCTGGAA
TCCGGGCAAAGTTCCCCAACAAAATCCCGGTGGTAGTGGAGCGCTACCCCAGGGAGACGTTCCTGCCCCCGCTGGACAAA
ACCAAGTTCCTGGTCCCGCAGGAGCTGACCATGACCCAGTTCCTCAGCATCATCCGGAGCCGCATGGTCCTGAGAGCCAC
GGAAGCCTTTTACTTGCTGGTGAACAACAAGAGCCTGGTCAGCATGAGCGCAACCATGGCAGAGATCTACAGAGACTACA
AGGATGAGGATGGCTTCGTGTACATGACCTACGCCTCCCAGGAGACATTTGGCTGCCTGGAGTCAGCAGCCCCCAGGGAT
GGGAGCAGCCTTGAGGACAGACCCTGCAATCCTCTCTAGCCCATGTCGGGAAGGATGTGTGCTCTGACAGACGTGTCAGA
TGCTGGCAGAAGGGATTGGTTTTCTCCTGTGTATACAGTGGAGGAGTCTGAGAAGCAGGGATGCCTGGGGTGATCAGCTC
CAACCAGTGGCAGCAGAGTGGTGGCTCTTCCTAGTTTAGTTTTTGTGCTCCGTGTTCTTGTGTCCTTCTAAGAAAAATGT
GGGCTGCTCTTGAAAGTTATATAATTATCATTTTTTTTTTTTTGAAACAGGGTCTTGCTCTATTGCCTAGGCTGGAGCAC
AGTGGCATGATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTTCTGCCTCCACCCCCCGAGTGGCTGG
TATTACAAGCACATGCCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTG
GTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCATC
CAGCCATATAACCGTATTCTAAATAAGAAATGGTTGGCTTGTGTGATGGTTTTGTGTAATGAGCTAGAGATAATATTTTA
AGTGTCTTCTGTGGTATATGTGGGAGGGCCATTAAGGAGTGGGTTTCACTCCCTGCATGTGGGCAGGTGTCC
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| Exon number |
1
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| Length |
133 nt
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| Location |
Chromosome 1 (NC_000001.10) : 242162252...242162384 (-)
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| Is part of |
MAP1LC3C, mRNA isoform 1
(NM_001004343.2)
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| Sequence |
Show
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GGAGGAATGAGTTAGGTTCCCGGTTGCGGGACAGTTTTTTTTTCTTTTTTAAAACAGACACAGCTACTGAGTGCAATGCC
GCCTCCACAGAAAATCCCAAGCGTCAGACCCTTCAAGCAGAGGAAAAGCTTGG
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| Exon number |
4
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| Length |
896 nt
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| Location |
Chromosome 1 (NC_000001.10) : 242158791...242159686 (-)
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| Is part of |
MAP1LC3C, mRNA isoform 1
(NM_001004343.2)
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| Sequence |
Show
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GAGCCGCATGGTCCTGAGAGCCACGGAAGCCTTTTACTTGCTGGTGAACAACAAGAGCCTGGTCAGCATGAGCGCAACCA
TGGCAGAGATCTACAGAGACTACAAGGATGAGGATGGCTTCGTGTACATGACCTACGCCTCCCAGGAGACATTTGGCTGC
CTGGAGTCAGCAGCCCCCAGGGATGGGAGCAGCCTTGAGGACAGACCCTGCAATCCTCTCTAGCCCATGTCGGGAAGGAT
GTGTGCTCTGACAGACGTGTCAGATGCTGGCAGAAGGGATTGGTTTTCTCCTGTGTATACAGTGGAGGAGTCTGAGAAGC
AGGGATGCCTGGGGTGATCAGCTCCAACCAGTGGCAGCAGAGTGGTGGCTCTTCCTAGTTTAGTTTTTGTGCTCCGTGTT
CTTGTGTCCTTCTAAGAAAAATGTGGGCTGCTCTTGAAAGTTATATAATTATCATTTTTTTTTTTTTGAAACAGGGTCTT
GCTCTATTGCCTAGGCTGGAGCACAGTGGCATGATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTTC
TGCCTCCACCCCCCGAGTGGCTGGTATTACAAGCACATGCCACCACACCAGGCTAATTTTTGTATTTTTAGTAGAGACGG
GGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGCTGGG
ATTACAGGCGTGAGCCACTGCATCCAGCCATATAACCGTATTCTAAATAAGAAATGGTTGGCTTGTGTGATGGTTTTGTG
TAATGAGCTAGAGATAATATTTTAAGTGTCTTCTGTGGTATATGTGGGAGGGCCATTAAGGAGTGGGTTTCACTCCCTGC
ATGTGGGCAGGTGTCC
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| Primary source |
Uniprot : Q9BXW4
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| Name |
Microtubule-associated proteins 1A/1B light chain 3C
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| Alternative name(s) |
Autophagy-related protein LC3 C
Autophagy-related ubiquitin-like modifier LC3 C
MAP1 light chain 3-like protein 3
MAP1A/MAP1B light chain 3 C
Microtubule-associated protein 1 light chain 3 gamma
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| Synonym(s) |
MAP1A/MAP1B LC3 C
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| Organism |
Homo sapiens
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| Length |
147 aa
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| Protein existence |
---
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General annotation (Comments)
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top
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Function
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Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity).
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Ptm
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The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
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Similarity
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Belongs to the MAP1 LC3 family.
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Subcellular location
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Cytoplasm. Endomembrane system; Lipid- anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes.
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Subunit
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3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity).
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Tissue specificity
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Most abundant in placenta, lung and ovary.
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Biological process
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autophagy [GO:0006914]
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Cellular component
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autophagic vacuole membrane [GO:0000421]
microtubule [GO:0005874]
endomembrane system [GO:0012505]
cytoplasmic vesicle [GO:0031410]
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Molecular function
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protein binding [GO:0005515]
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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Molecule processing
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Propeptide
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127 - 147
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21
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Removed in mature form
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PRO_0000017205
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Amino acid modifications
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Lipidation
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126 - 126
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1
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Phosphatidylethanolamine amidated glycine (Probable)
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Q9BXW4-LIPID-126
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Experimental info
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Mutagenesis
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126 - 126
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1
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G->A: No processing of precursor
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Q9BXW4-MUTAGEN-126
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| 1 |
MPPPQKIPSV |
RPFKQRKSLA |
IRQEEVAGIR |
AKFPNKIPVV |
VERYPRETFL |
PPLDKTKFLV |
PQELTMTQFL |
SIIRSRMVLR |
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| 81 |
ATEAFYLLVN |
NKSLVSMSAT |
MAEIYRDYKD |
EDGFVYMTYA |
SQETFGCLES |
AAPRDGSSLE |
DRPCNPL |
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>sp|Q9BXW4|MLP3C_human Microtubule-associated proteins 1A/1B light chain 3C
MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLVPQELTMTQFLSIIRSRMVLR
ATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYASQETFGCLESAAPRDGSSLEDRPCNPL
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