(EEF2) eukaryotic translation elongation factor 2 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  10098
 Official symbol  EEF2
 Official name  eukaryotic translation elongation factor 2
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 19 (NC_000019.9) :  3976053...3985460  (-)
 Map  19pter-q12
 Length  9408  nt
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Alternative name(s) and Synynom(s) top
Synonyms EF2; EEF-2
Alternative name(s) polypeptidyl-tRNA translocase
External Links top
Ensembl ENSG00000167658
Entrez 1938
HGNC 3214
HPRD 00561
Comment top
Summary This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  TCTTCCGCCG TCGTCGCCGC CATCCTCGGC GCGACTCGCT TCTTTCGGTT CTACCTGGGA GAATCCACCG CCATCCGCCA
81  CCATGGTGAG TAACCCTGCC TCGCTGGTGC CCCGGAGCGG CGGCGGGGCC TCCGCGGGGC CTACGCTGCC TAGCCTGGGA
161  CGCTGGGGCC CCCCGTGCCA GGAGGAGACG TAGCGGCGGC GGGGCCGGAG GACCCGGGGC TGGGGAAGCG GCCGCCGCCA
241  TGTCTGTGCG CCGCGCTGTT CACCGAGCCC TTTCTCCGTT TCCGAGGGCG CCATAACCTT GCCCAGACCT GGTTGGAGCT
321  GGGTTGTTAG CGGGGATGGG GGTGGGGAAT GATGATGTGG CAGGCGTAGT AATGGCGGGC ACCGCGGTGG AAGCGGGGAG
401  ACAGGGAGGC GCCTTATGTA ACCCGCGGGC CGCGAGTTTG AGATCGATTT TCTGCCGGGG GACTAGGGGC GGCAGGGAAT
481  GGCAGAACGA GCAAAGCGAC ACCTGAAAGG CTCCCCTTTT CCTTCCAAAT ACCTTCTCCT GATGCTGTTA ATCGTCGACC
561  TTAGGCACTT GTCCTTCCTA TGACTCCCAG ATGTACAAAG ACTCTTATTG AGACACGAGG TGTAGGCTTG TGGCAGTTAG
641  GGCCGTTCCG GCTCCCCGTT ATTTCCTGGG GTGGGTGGCC TTGTCTGATC CCGTTTGCCA AGGGGTGACC TTGCATTTTA
721  TGATGAAGCT TCTTGCTCGG GGAAGTTTGG GTGGCCCGGT GACAACGTGG AGGGGGCTTT AGGAGAGGAT TCATCCCTTA
801  CGTGTTTGGC CCCAAATGAG ACTTTAGTAT TTGTACCTGG TATCAAGGAA ATCTGTTGAC ACTCAGTTTT ATTCCTGAGC
881  ACTTTTATTT CTGGGTTGTC AATCATGAAT GACACCTATT AACGGTGGTT CCTTGGAGAT TGCGGGGTGG CTCTTAAGGG
961  GTGTTAGGCT GGCAAGATTC GGTGGGCTTG GGGCACCCCA GCACCAACCC CCTCCTGGCC TTGGGCATGC TGGTTCGTTT
1041  GGACTGAACG CTCCGTGCCA TGCTGTGTTC CTGGAAATCA CGAGCTGGTC TGAGCCTCCT TGTCTTGCCC AGGTGAACTT
1121  CACGGTAGAC CAGATCCGCG CCATCATGGA CAAGAAGGCC AACATCCGCA ACATGTCTGT CATCGCCCAC GTGGACCATG
1201  GCAAGTCCAC GCTGACAGAC TCCCTGGTGT GCAAGGCGGG CATCATCGCC TCGGCCCGGG CCGGGGAGAC ACGCTTCACT
1281  GATACCCGGA AGGACGAGCA GGAGCGTTGC ATCACCATCA AGTCAACGTG AGCTCCCTGT GCCCTCTGTA CCCAGGCAGG
1361  GAGGTGCTGG CCTGGCAGCT GGAGGCCACT GGGCCAGGGT GCGCGGGGAG AGACTTGGCA ACGTCTCTTT CCCCTGGTTT
1441  CTTAATTCAT GGGAGAATGA GTGAGGTTCA GTCCAGCGAG ACAGGATGGA GAGGCACAGG GATTCGGGGT ACTGCGAGCT
1521  GGAAGGTTTT CTTGAGGAGG GGGCTTAACT CCGTGGTTCT CCCTCCCTGG GGGACTTGCC CCCACTCCTA CAATATCTGG
1601  AGAGGTTTGG CTGTCACACC TGGGAGGGGA GGGTGTTCTA GTGCTTGGGA CGCTGGGAAG CTCCTGTGTT GCACTGGATG
1681  ATGTTCATTC CATGTCAGTT TCTGGCCCCG ATATGAGTAG GGGGAGCGCA GAGTACGGTG ACCCCAACTG CTTTTTGTCC
1761  TGGGTTGGTA CATTGGTGAG GGACTCTGGC TAAGGCTCTT CATTTCCCCT GGAGCAGGGG CAGAAGTGAG GAGGGGAGGG
1841  TCGGAGTCTC TGGAGGCTTT TGCCGTCCTG CTGGGTCTTT TAGTTGCTAC TTTGAGTCAG GTGTGATGAA TCTTGGGACC
1921  AAGTCGGTGG GGCAGGATGT CTGGTCAGGA GGGCTCTGAG GATCTGGCTA TGGGGCTGGT ACCAGGAGTT CCCTGTCATG
2001  GGGGTGGCAT GTCTCGGACA GAGGCAAAGG ACAAGGGTGG GTTGGCTCTT GTGGGAGCCT CTCCAGGGAT GAGTCATGGA
2081  GGGAGGAGCA GCCTGGCTTC TGACAGCATC CCAGACTCCC TGGGCCAGGT GTGTGGCTCC TGTCCCCCTG ACGAGTCCCT
2161  CCCTCCATCA GTGCCATCTC CCTCTTCTAC GAGCTCTCGG AGAATGACTT GAACTTCATC AAGCAGAGCA AGGACGGTGC
2241  CGGCTTCCTC ATCAACCTCA TTGACTCCCC CGGGCATGTC GACTTCTCCT CGGAGGTGAC TGCTGCCCTC CGAGTCACCG
2321  ATGGCGCATT GGTGGTGGTG GACTGCGTGT CAGGTAAGCA GTGGGTCCCC CTGAGGCACG GCCTGGAACC GGGGGCCATC
2401  CTTGCTTGAG GATGACAGCG CCGCCCTGTC CCCCGTGTCC CCAGGCGTGT GCGTGCAGAC GGAGACAGTG CTGCGGCAGG
2481  CCATTGCCGA GCGCATCAAG CCTGTGCTGA TGATGAACAA GATGGACCGC GCCCTGCTGG AGCTGCAGCT GGAGCCCGAG
2561  GAGCTCTACC AGACTTTCCA GCGCATCGTG GAGAACGTGA ACGTCATCAT CTCCACCTAC GGCGAGGGCG AGAGCGGCCC
2641  CATGGGCAAC ATCATGGTAC GGCCCTCCCT AGCTGGGTGG TGGGCTTGCC GCAGCGGGAT CTGCAGGAGC CGGTGGGGAG
2721  TGGAGTTGAG CTGAGGGGGA CTGGAAGTGT GTTTTTGCCA GGAATGTTGG GTGACAGAGA AGGGGGCTGG AATGTTTTCA
2801  TCCGACTTGA CCCAGCCCTT GATCTTTGGG CAGCTGGAAG AGACGAGCTC AGGGAACGCT GCCCTGGGTG GTGGAGGGGC
2881  TGGCCCCCCT ATTCGTGATG ACTGATCATT TCTTCACTTT GACCAGATGT CTACTGAAGA AAGCCTGCGT CTGAGGCCCA
2961  TGCCCAAGGC GCCCAGCCCG TAGCTTCAGG CTCTGCGCAG GGGCCCTCAC GGCTGCTTCT CGTTTCTCAC ACTTCCAGAT
3041  CGATCCTGTC CTCGGTACCG TGGGCTTTGG GTCTGGCCTC CACGGGTGGG CCTTCACCCT GAAGCAGTTT GCCGAGATGT
3121  ATGTGGCCAA GTTCGCCGCC AAGGGGGAGG GCCAGTTGGG GCCTGCCGAG CGGGCCAAGA AAGTAGAGGA CATGATGAAG
3201  AAGCTGTGGG GTGACAGGTG AGCCCCGCGG GATATGGTGG GGGATTCCTG ACACCTGGGG GTAGTGGCAG CGACGTAGGG
3281  GCGTGGTGTG CTATTCACAG CGTGGCTCAA GCCCACCAGG TCTTGCCCAA GCATGTCCCC TTGGCGACCA CCCTCCCCAA
3361  GTCATCCCCT GGAGACCCTA ACTTGATTTG GCTTGGCCTC TCCTTGCCAG GTACTTTGAC CCAGCCAACG GCAAGTTCAG
3441  CAAGTCAGCC ACCAGCCCCG AAGGGAAGAA GCTGCCACGC ACCTTCTGCC AGCTGATCCT GGACCCCATC TTCAAGGTGA
3521  GTGAGGGCTG CGCCAGGCAC CCCGCCGATG CGACTATTGG CCCTCGGCCC TGTGGGCTCC GGCCGGTAGC CTGTCGGCTG
3601  ACTGGGCCCG TCTCCTTGTG GGGCAGATGC GAGATGGGAG GAGGCACAGC TCCTAACTGA GGTGGAGTCA GGGCTCCTCT
3681  CTTAAGATCT GGACTGCATA GCCAGAGCCT TGGGACCTCT CCTGCATTGA GGGGGTTGAA TAACTTGTGG CTTTGGCGGT
3761  TCAGTGCTTG TAAGTCAGAA CTTGGGTCCT TGTCTGAGTC AGAGTGGGCT TTTTCCTCTG CTCCACCACG AGGTTTCCTC
3841  CAGCTCCCGA TCCGCTCAGC TGGCTGGGCC CGTGGTAGGC AGGCCAGGCC TGCTCCTGCT CCCGTGCTGC GTCCCCCTGC
3921  GCTGACCTGA GTCTTCCAAG CAGGAAGCAG TGCCAGGCTT CCTCCTGCTG TTCCCAAATG GGCTTTCTTG TTTCTTGGTG
4001  GGGAATGTAG GTGTTTGATG CGATCATGAA TTTCAAGAAA GAGGAGACAG CAAAACTGAT AGAGAAACTG GACATCAAAC
4081  TGGACAGCGA GGACAAGGAC AAAGAAGGCA AACCCCTGCT GAAGGTGCGG CCTGGGCCCA GCCCTCGGGG TGGAGGGAAC
4161  ACAGGCTGCT GTTTCCGGAT GCTCTGACAG CCCAGGCCTG GGGGCTGAAG TCCTCAGCTG GGCAGGGACA GCTGCTGCCC
4241  CTTTCGCTTT AGACTCTGGG TGCTGCTGGA GACACATCCC AGCAGCCAGC CCCATCCGGG ACAGGTGTGG GTGAGGGCCT
4321  TGGCAGGAGT GTGCATGGCC TTTGCCGCCT TCCAGAAGGG ACTGTGCTTT GGAGAACGTT AGTCCTGACT TTGGCTTCCT
4401  TGGCTTCAAG AGAGGAAGCG TGTACGGGGT GGGGCCATCC TGGGCTCCCC AGGTGTCTCA TGCACCGCTC TCTGCCCCCG
4481  CAGGCTGTGA TGCGCCGCTG GCTGCCTGCC GGAGACGCCT TGTTGCAGAT GATCACCATC CACCTGCCCT CCCCTGTGAC
4561  GGCCCAGAAG TACCGCTGCG AGCTCCTGTA CGAGGGGCCC CCGGACGACG AGGCTGCCAT GGGTACGTGG TCCCGGTGGC
4641  CGGGCCCTGA GATGCAGCCG GATGACTTCC TGTTGCCCAA GGTTGTGGGT TGCAGGGTTC CAGAAGGCTG AGCTGCACTG
4721  GAATAAAGCT TGCGGGTTTT CTCTGTCCCT CAGGCATTAA AAGCTGTGAC CCCAAAGGCC CTCTTATGAT GTATATTTCC
4801  AAAATGGTGC CAACCTCCGA CAAAGGTCGG TTCTACGCCT TTGGACGAGT CTTCTCGGGG CTGGTCTCCA CTGGCCTGAA
4881  GGTCAGGATC ATGGGGCCCA ACTATACCCC TGGGAAGAAG GAGGACCTCT ACCTGAAGCC AATCCAGAGG TGAGCAGCTG
4961  GGTGATGTGC AGGCCCCTTG GCACTGTTGC GGGCCCTGCC CTGCTCCAAG TCTTGGGCTC CTCAGTCGGG AGCTAGAAGT
5041  AAGGAGCATA GAAGGAATAT AGGGTGATAC TTGTGCCAGC CACAACTTTT GTTCTTAGCC CAGTGAGGGC ATTTCTGGAG
5121  AAGCTCCAAG CCCCAGGGCA CAGCACACCC CTGCTCATCT GTGTCCCTGG GCACAGGTGG GTGGCGGCCG TCGACCCATA
5201  CCCAGGGAGG AGGGCAGTGA TTCTGAAGAG GATGTTTCCT GACAGCCCCG ACGCAGCAGT CAGGGCCTTG TGGAAGCCAC
5281  CAGTCTGCCC TGGGACCTGG CAGGAGGGCC ACCAACTCCG GGAGGGACCT GCCCTGGCCC TCCAGGGTCC AGCACAACCA
5361  TCCCTGCGGC CTGCTGCCGC CTTCTGCTTC TTCCAGAACA ATCTTGATGA TGGGCCGCTA CGTGGAGCCC ATCGAGGATG
5441  TGCCTTGTGG GAACATTGTG GGCCTCGTGG GCGTGGACCA GTTCCTGGTG AAGACGGGCA CCATCACCAC CTTCGAGCAC
5521  GCGCACAACA TGCGGGTGAT GAAGTTCAGC GTCAGCCCTG TTGTCAGAGT GGCCGTGGAG GCCAAGAACC CGGCTGACCT
5601  GCCCAAGCTG GTGGAGGGGC TGAAGCGGCT GGCCAAGTCC GACCCCATGG TGCAGGTGGG CACGGAGTGC ACCTGCTGGG
5681  AGCAGACACC CTGAGGGGGG ACGGCTTGTG TCCTGAGTTG TGGCTGTGTG GGTTGCTGTG GTTGGTGGAT TGGGGTGACT
5761  GGTCATGAAA GGAGGGGTTC TTGGCTGTGG CTGTAAATGG AGACTCCTGC CCAGGCAGCC ACCACCCTCT CCTAGGCTGC
5841  TCTGCGCGTG TTCACTGTAG CTTGTGGGAC TTAACATTTC TTCAGGAGTT TGTGCTGGTC CCAGTTTCCC AGCACCTTCC
5921  CTGAAATCTT GTTCTGGCGG GGTCCCTAGC TAAAGGGAAG CTGGGAGCCT GGTCCCGCCT GTTCCGAGCC GCCTACCCCT
6001  TTGGTGCTGA CCCGCATCCC TTTCAGTGCA TCATCGAGGA GTCGGGAGAG CATATCATCG CGGGCGCCGG CGAGCTGCAC
6081  CTGGAGATCT GCCTGAAGGA CCTGGAGGAG GACCACGCCT GCATCCCCAT CAAGGTGAGG CGCCAGTGAC CAGCCTTCCC
6161  CACGCCCCAC CCCGGACACC TGCCCTCTGC TTTAAAGCTG AGCTGAGCTA GGCTCTGCAG ACGCCTAGAC TTGATCTCGG
6241  TCTTGGTCTC AGCTTCTTAA GTTCCTCAAG TTTCTTCTTT GCAGTCTTCC ACAGGCATGT GGGGCTGTTT TTGTTGTTGT
6321  TGTTGTTTTT TTTGAGATAG TCTCGCTGTG TCATCCAGGC TGGAGTGCAG TGGCGTGATC TTGGCTCGCT AGAACCTCCA
6401  CCTCCCGGGT TCAAGCGATT CTCTTGCCTC ACTCAGCTTC CTGAGTAACT GGGACTACAG GCGCGTGCTA CCACGCCCGG
6481  CTAATTTTTT TTTGTATTTT TAGTAGAGGC GGGGTTTCAC TGTGTTAGTA AGTCAAGATG GTCTCGATCT CCTGACCTCG
6561  TGATCCCCCT GCCTCGGCCT CCCAAAGTGC TGGGATTACA GGTGTGAGCC ACCATGCCTG GCCCAGGGCT ATTTTTTTTT
6641  TTTTTTTTTT TTTTTTTTTG AGACAAGAGT CTTGCTCTGT TGCTTAGGCT GGAGTGCAAT GGCGTGATCT TGGCTCACTG
6721  CAAGCTCTGC TTCCCAGGTT CACGCCATTC TCCTGCCTCA GCCTCCTGTA GCTGGGACTT CAGGCGCCTG CCATCATGCC
6801  CGGCTAATTT TTTGCATTTT TAGTAGAGAC GGGGTTTCAC CGTGTTAGCC AGGATGGTCT GGATCTCCTG ACCTCGTGAT
6881  CCACCCGCCT CGGCCTCCCA AAGTGCTGGG ATTACAGGCG TGAGCCACCA CGCCCGGCCT CCGGGGCAGT TTTTGAGTTA
6961  CATCCTGCTG TCTTCTGTCC ACAAACAACA CAAATGCTCT GGAGGGGTTG GGACAGGCCT GCTCCAGACC TCGTTTCTTC
7041  CCTGTTAATG CTTAAAATTC CACAAGCCCG TGGTTTCTGC GCCGGAGAGC TCAGTGGAGC CCCTGCTCCT TGTCCTTGTC
7121  TGGAGTGAGA TGCGCTTGGC ACTGCAACAC TGACTCCGCT TCGTTCTGAT TGACGTGGCT CTACCAGGCT GTATGAGGTC
7201  CGCCTTGCTA GGAAAAGCTT TTAAGGATGC GTCTGTGTGT AAGGTCACCT CTTTCTCCAG GCAAGAGTGG GACTTAACCT
7281  CTTTTTGCAG AAATCTGACC CGGTCGTCTC GTACCGCGAG ACGGTCAGTG AAGAGTCGAA CGTGCTCTGC CTCTCCAAGT
7361  CCCCCAACAA GCACAACCGG CTGTACATGA AGGCGCGGCC CTTCCCCGAC GGCCTGGCCG AGGACATCGA TAAAGGCGAG
7441  GTGTCCGCCC GTCAGGAGCT CAAGCAGCGG GCGCGCTACC TGGCCGAGAA GTACGAGTGG GACGTGGCTG AGGCCCGCAA
7521  GATCTGGTGC TTTGGGCCCG ACGGCACCGG CCCCAACATC CTCACCGACA TCACCAAGGG TGTGCAGTAC CTCAACGAGA
7601  TCAAGGACAG TGTGGTGGCC GGCTTCCAGT GGGCCACCAA GGAGGTGAGG CACGGCTCAG CATGTGCAGA CCACACCCGT
7681  TTCCAGGCTC TAGAGGGACC TCATGGTCCT GCCTCCCGAG ACAGAGACCC TAATGGGGCC AAGGCGGGCA AGGCCCCAGG
7761  TCCCCCTGGT GGAGACCTGC AGGACTTGGC AGGTGGAGGG CAAGCAGCCG AGGTGTGTCC GGCCCTTGAC GGTGGCTCTC
7841  CCCCTCCCCC AGGGCGCACT GTGTGAGGAG AACATGCGGG GTGTGCGCTT CGACGTCCAC GACGTCACCC TGCACGCCGA
7921  CGCCATCCAC CGCGGAGGGG GCCAGATCAT CCCCACAGCA CGGCGCTGCC TCTATGCCAG TGTGCTGACC GCCCAGCCAC
8001  GCCTCATGGA GCCCATCTAC CTTGTGGAGA TCCAGGTGAG GTCTACCCGC CCACCGCTGA CCCTGCCACC GTCCTGCCCA
8081  GCGGCCACTG ACAGGTTTTC TTTCCCTTCT GGCAGTGTCC AGAGCAGGTG GTCGGTGGCA TCTACGGGGT TTTGAACAGG
8161  AAGCGGGGCC ACGTGTTCGA GGAGTCCCAG GTGGCCGGCA CCCCCATGTT TGTGGTCAAG GCCTATCTGC CCGTCAACGA
8241  GTCCTTTGGT GAGTGCCTGC CCGGTGTGGC CTGCAGAGCC TGGCAGGCTG GTTTGGGGGA CAGAAGCCCA GTTAAGCTTA
8321  GCAAGGTGTT AAAGGAGGCG TCCTGATGGG AGCAGGTGAT GGATGGAGCA GGTGGTCCAG TTTCTGACAG CTTGTGGACC
8401  CCCTAAATCA CTGAATTCCC AGGGGAGGGG CTCTCCTATC CCCAGTGTGA GAAGGGCTCT GGGCCTGGAG CTCTGAAGGC
8481  CTACGCCCTG GGCCGGTAGA GCAGCCGAGC TGTAGCACAG GGTTGTCCCA AACGAGCAGC GGCATGAGGC CCATGAGTGG
8561  CCTGCTAGGC CCTTCGTGAA GTGCTGGGCA CCAGGCCGAG TGTCTGGTCT GCAGGGTGAC TCAGGCTGAG GAACTAGCCT
8641  GAGCTCCTGA CAGGACTTTC CTTCTGCCCT GCCACCTTCT CGATGGCCCA GTGAGCCTCT CGCTTCCCTC TGCAGGCTTC
8721  ACCGCTGACC TGAGGTCCAA CACGGGCGGC CAGGCGTTCC CCCAGTGTGT GTTTGACCAC TGGCAGATCC TGCCCGGAGA
8801  CCCCTTCGAC AACAGCAGCC GCCCCAGCCA GGTGGTGGCG GAGACCCGCA AGCGCAAGGG CCTGAAAGAA GGCATCCCTG
8881  CCCTGGACAA CTTCCTGGAC AAATTGTAGG CGGCCCTTCC TGCAGCGCCT GCCGCCCCGG GGACTCGCAG CACCCACAGC
8961  ACCACGTCCT CGAATTCTCA GACGACACCT GGAGACTGTC CCGACACAGC GACGCTCCCC TGAGAGGTTT CTGGGGCCCG
9041  CTGCGTGCCA TCACTCAACC ATAACACTTG ATGCCGTTTC TTTCAATATT TATTTCCAGA GTCCGGAGGC AGCAGACACG
9121  CCCTCTTAGT AGGGACTTAA TGGGCCGGTC GGGGAGGGGG AGGCGGGATG GGACACCCAA CACTTTTTCC ATTTCTTCAG
9201  AGGGAAACTC AGATGTCCAA ACTAATTTTA ACAAACGCAT TAAGAGGTTT ATTTGGGTAC ATGGCCCGCA GTGGCTTTTG
9281  CCCCAGAAAG GGGAAAGGAA CACGCGGGTA GATGATTTCT AGCAGGCAGG AAGTCCTGTG CGGTGTCACC ATGAGCACCT
9361  CCAGCTGTAC TAGTGCCATT GGAATAATAA ATTTGATAAG GTGGTGAC
>ref|Gene_ID:1938|EEF2|NC_000019.9:3976053...3985460 (-)
TCTTCCGCCGTCGTCGCCGCCATCCTCGGCGCGACTCGCTTCTTTCGGTTCTACCTGGGAGAATCCACCGCCATCCGCCA
CCATGGTGAGTAACCCTGCCTCGCTGGTGCCCCGGAGCGGCGGCGGGGCCTCCGCGGGGCCTACGCTGCCTAGCCTGGGA
CGCTGGGGCCCCCCGTGCCAGGAGGAGACGTAGCGGCGGCGGGGCCGGAGGACCCGGGGCTGGGGAAGCGGCCGCCGCCA
TGTCTGTGCGCCGCGCTGTTCACCGAGCCCTTTCTCCGTTTCCGAGGGCGCCATAACCTTGCCCAGACCTGGTTGGAGCT
GGGTTGTTAGCGGGGATGGGGGTGGGGAATGATGATGTGGCAGGCGTAGTAATGGCGGGCACCGCGGTGGAAGCGGGGAG
ACAGGGAGGCGCCTTATGTAACCCGCGGGCCGCGAGTTTGAGATCGATTTTCTGCCGGGGGACTAGGGGCGGCAGGGAAT
GGCAGAACGAGCAAAGCGACACCTGAAAGGCTCCCCTTTTCCTTCCAAATACCTTCTCCTGATGCTGTTAATCGTCGACC
TTAGGCACTTGTCCTTCCTATGACTCCCAGATGTACAAAGACTCTTATTGAGACACGAGGTGTAGGCTTGTGGCAGTTAG
GGCCGTTCCGGCTCCCCGTTATTTCCTGGGGTGGGTGGCCTTGTCTGATCCCGTTTGCCAAGGGGTGACCTTGCATTTTA
TGATGAAGCTTCTTGCTCGGGGAAGTTTGGGTGGCCCGGTGACAACGTGGAGGGGGCTTTAGGAGAGGATTCATCCCTTA
CGTGTTTGGCCCCAAATGAGACTTTAGTATTTGTACCTGGTATCAAGGAAATCTGTTGACACTCAGTTTTATTCCTGAGC
ACTTTTATTTCTGGGTTGTCAATCATGAATGACACCTATTAACGGTGGTTCCTTGGAGATTGCGGGGTGGCTCTTAAGGG
GTGTTAGGCTGGCAAGATTCGGTGGGCTTGGGGCACCCCAGCACCAACCCCCTCCTGGCCTTGGGCATGCTGGTTCGTTT
GGACTGAACGCTCCGTGCCATGCTGTGTTCCTGGAAATCACGAGCTGGTCTGAGCCTCCTTGTCTTGCCCAGGTGAACTT
CACGGTAGACCAGATCCGCGCCATCATGGACAAGAAGGCCAACATCCGCAACATGTCTGTCATCGCCCACGTGGACCATG
GCAAGTCCACGCTGACAGACTCCCTGGTGTGCAAGGCGGGCATCATCGCCTCGGCCCGGGCCGGGGAGACACGCTTCACT
GATACCCGGAAGGACGAGCAGGAGCGTTGCATCACCATCAAGTCAACGTGAGCTCCCTGTGCCCTCTGTACCCAGGCAGG
GAGGTGCTGGCCTGGCAGCTGGAGGCCACTGGGCCAGGGTGCGCGGGGAGAGACTTGGCAACGTCTCTTTCCCCTGGTTT
CTTAATTCATGGGAGAATGAGTGAGGTTCAGTCCAGCGAGACAGGATGGAGAGGCACAGGGATTCGGGGTACTGCGAGCT
GGAAGGTTTTCTTGAGGAGGGGGCTTAACTCCGTGGTTCTCCCTCCCTGGGGGACTTGCCCCCACTCCTACAATATCTGG
AGAGGTTTGGCTGTCACACCTGGGAGGGGAGGGTGTTCTAGTGCTTGGGACGCTGGGAAGCTCCTGTGTTGCACTGGATG
ATGTTCATTCCATGTCAGTTTCTGGCCCCGATATGAGTAGGGGGAGCGCAGAGTACGGTGACCCCAACTGCTTTTTGTCC
TGGGTTGGTACATTGGTGAGGGACTCTGGCTAAGGCTCTTCATTTCCCCTGGAGCAGGGGCAGAAGTGAGGAGGGGAGGG
TCGGAGTCTCTGGAGGCTTTTGCCGTCCTGCTGGGTCTTTTAGTTGCTACTTTGAGTCAGGTGTGATGAATCTTGGGACC
AAGTCGGTGGGGCAGGATGTCTGGTCAGGAGGGCTCTGAGGATCTGGCTATGGGGCTGGTACCAGGAGTTCCCTGTCATG
GGGGTGGCATGTCTCGGACAGAGGCAAAGGACAAGGGTGGGTTGGCTCTTGTGGGAGCCTCTCCAGGGATGAGTCATGGA
GGGAGGAGCAGCCTGGCTTCTGACAGCATCCCAGACTCCCTGGGCCAGGTGTGTGGCTCCTGTCCCCCTGACGAGTCCCT
CCCTCCATCAGTGCCATCTCCCTCTTCTACGAGCTCTCGGAGAATGACTTGAACTTCATCAAGCAGAGCAAGGACGGTGC
CGGCTTCCTCATCAACCTCATTGACTCCCCCGGGCATGTCGACTTCTCCTCGGAGGTGACTGCTGCCCTCCGAGTCACCG
ATGGCGCATTGGTGGTGGTGGACTGCGTGTCAGGTAAGCAGTGGGTCCCCCTGAGGCACGGCCTGGAACCGGGGGCCATC
CTTGCTTGAGGATGACAGCGCCGCCCTGTCCCCCGTGTCCCCAGGCGTGTGCGTGCAGACGGAGACAGTGCTGCGGCAGG
CCATTGCCGAGCGCATCAAGCCTGTGCTGATGATGAACAAGATGGACCGCGCCCTGCTGGAGCTGCAGCTGGAGCCCGAG
GAGCTCTACCAGACTTTCCAGCGCATCGTGGAGAACGTGAACGTCATCATCTCCACCTACGGCGAGGGCGAGAGCGGCCC
CATGGGCAACATCATGGTACGGCCCTCCCTAGCTGGGTGGTGGGCTTGCCGCAGCGGGATCTGCAGGAGCCGGTGGGGAG
TGGAGTTGAGCTGAGGGGGACTGGAAGTGTGTTTTTGCCAGGAATGTTGGGTGACAGAGAAGGGGGCTGGAATGTTTTCA
TCCGACTTGACCCAGCCCTTGATCTTTGGGCAGCTGGAAGAGACGAGCTCAGGGAACGCTGCCCTGGGTGGTGGAGGGGC
TGGCCCCCCTATTCGTGATGACTGATCATTTCTTCACTTTGACCAGATGTCTACTGAAGAAAGCCTGCGTCTGAGGCCCA
TGCCCAAGGCGCCCAGCCCGTAGCTTCAGGCTCTGCGCAGGGGCCCTCACGGCTGCTTCTCGTTTCTCACACTTCCAGAT
CGATCCTGTCCTCGGTACCGTGGGCTTTGGGTCTGGCCTCCACGGGTGGGCCTTCACCCTGAAGCAGTTTGCCGAGATGT
ATGTGGCCAAGTTCGCCGCCAAGGGGGAGGGCCAGTTGGGGCCTGCCGAGCGGGCCAAGAAAGTAGAGGACATGATGAAG
AAGCTGTGGGGTGACAGGTGAGCCCCGCGGGATATGGTGGGGGATTCCTGACACCTGGGGGTAGTGGCAGCGACGTAGGG
GCGTGGTGTGCTATTCACAGCGTGGCTCAAGCCCACCAGGTCTTGCCCAAGCATGTCCCCTTGGCGACCACCCTCCCCAA
GTCATCCCCTGGAGACCCTAACTTGATTTGGCTTGGCCTCTCCTTGCCAGGTACTTTGACCCAGCCAACGGCAAGTTCAG
CAAGTCAGCCACCAGCCCCGAAGGGAAGAAGCTGCCACGCACCTTCTGCCAGCTGATCCTGGACCCCATCTTCAAGGTGA
GTGAGGGCTGCGCCAGGCACCCCGCCGATGCGACTATTGGCCCTCGGCCCTGTGGGCTCCGGCCGGTAGCCTGTCGGCTG
ACTGGGCCCGTCTCCTTGTGGGGCAGATGCGAGATGGGAGGAGGCACAGCTCCTAACTGAGGTGGAGTCAGGGCTCCTCT
CTTAAGATCTGGACTGCATAGCCAGAGCCTTGGGACCTCTCCTGCATTGAGGGGGTTGAATAACTTGTGGCTTTGGCGGT
TCAGTGCTTGTAAGTCAGAACTTGGGTCCTTGTCTGAGTCAGAGTGGGCTTTTTCCTCTGCTCCACCACGAGGTTTCCTC
CAGCTCCCGATCCGCTCAGCTGGCTGGGCCCGTGGTAGGCAGGCCAGGCCTGCTCCTGCTCCCGTGCTGCGTCCCCCTGC
GCTGACCTGAGTCTTCCAAGCAGGAAGCAGTGCCAGGCTTCCTCCTGCTGTTCCCAAATGGGCTTTCTTGTTTCTTGGTG
GGGAATGTAGGTGTTTGATGCGATCATGAATTTCAAGAAAGAGGAGACAGCAAAACTGATAGAGAAACTGGACATCAAAC
TGGACAGCGAGGACAAGGACAAAGAAGGCAAACCCCTGCTGAAGGTGCGGCCTGGGCCCAGCCCTCGGGGTGGAGGGAAC
ACAGGCTGCTGTTTCCGGATGCTCTGACAGCCCAGGCCTGGGGGCTGAAGTCCTCAGCTGGGCAGGGACAGCTGCTGCCC
CTTTCGCTTTAGACTCTGGGTGCTGCTGGAGACACATCCCAGCAGCCAGCCCCATCCGGGACAGGTGTGGGTGAGGGCCT
TGGCAGGAGTGTGCATGGCCTTTGCCGCCTTCCAGAAGGGACTGTGCTTTGGAGAACGTTAGTCCTGACTTTGGCTTCCT
TGGCTTCAAGAGAGGAAGCGTGTACGGGGTGGGGCCATCCTGGGCTCCCCAGGTGTCTCATGCACCGCTCTCTGCCCCCG
CAGGCTGTGATGCGCCGCTGGCTGCCTGCCGGAGACGCCTTGTTGCAGATGATCACCATCCACCTGCCCTCCCCTGTGAC
GGCCCAGAAGTACCGCTGCGAGCTCCTGTACGAGGGGCCCCCGGACGACGAGGCTGCCATGGGTACGTGGTCCCGGTGGC
CGGGCCCTGAGATGCAGCCGGATGACTTCCTGTTGCCCAAGGTTGTGGGTTGCAGGGTTCCAGAAGGCTGAGCTGCACTG
GAATAAAGCTTGCGGGTTTTCTCTGTCCCTCAGGCATTAAAAGCTGTGACCCCAAAGGCCCTCTTATGATGTATATTTCC
AAAATGGTGCCAACCTCCGACAAAGGTCGGTTCTACGCCTTTGGACGAGTCTTCTCGGGGCTGGTCTCCACTGGCCTGAA
GGTCAGGATCATGGGGCCCAACTATACCCCTGGGAAGAAGGAGGACCTCTACCTGAAGCCAATCCAGAGGTGAGCAGCTG
GGTGATGTGCAGGCCCCTTGGCACTGTTGCGGGCCCTGCCCTGCTCCAAGTCTTGGGCTCCTCAGTCGGGAGCTAGAAGT
AAGGAGCATAGAAGGAATATAGGGTGATACTTGTGCCAGCCACAACTTTTGTTCTTAGCCCAGTGAGGGCATTTCTGGAG
AAGCTCCAAGCCCCAGGGCACAGCACACCCCTGCTCATCTGTGTCCCTGGGCACAGGTGGGTGGCGGCCGTCGACCCATA
CCCAGGGAGGAGGGCAGTGATTCTGAAGAGGATGTTTCCTGACAGCCCCGACGCAGCAGTCAGGGCCTTGTGGAAGCCAC
CAGTCTGCCCTGGGACCTGGCAGGAGGGCCACCAACTCCGGGAGGGACCTGCCCTGGCCCTCCAGGGTCCAGCACAACCA
TCCCTGCGGCCTGCTGCCGCCTTCTGCTTCTTCCAGAACAATCTTGATGATGGGCCGCTACGTGGAGCCCATCGAGGATG
TGCCTTGTGGGAACATTGTGGGCCTCGTGGGCGTGGACCAGTTCCTGGTGAAGACGGGCACCATCACCACCTTCGAGCAC
GCGCACAACATGCGGGTGATGAAGTTCAGCGTCAGCCCTGTTGTCAGAGTGGCCGTGGAGGCCAAGAACCCGGCTGACCT
GCCCAAGCTGGTGGAGGGGCTGAAGCGGCTGGCCAAGTCCGACCCCATGGTGCAGGTGGGCACGGAGTGCACCTGCTGGG
AGCAGACACCCTGAGGGGGGACGGCTTGTGTCCTGAGTTGTGGCTGTGTGGGTTGCTGTGGTTGGTGGATTGGGGTGACT
GGTCATGAAAGGAGGGGTTCTTGGCTGTGGCTGTAAATGGAGACTCCTGCCCAGGCAGCCACCACCCTCTCCTAGGCTGC
TCTGCGCGTGTTCACTGTAGCTTGTGGGACTTAACATTTCTTCAGGAGTTTGTGCTGGTCCCAGTTTCCCAGCACCTTCC
CTGAAATCTTGTTCTGGCGGGGTCCCTAGCTAAAGGGAAGCTGGGAGCCTGGTCCCGCCTGTTCCGAGCCGCCTACCCCT
TTGGTGCTGACCCGCATCCCTTTCAGTGCATCATCGAGGAGTCGGGAGAGCATATCATCGCGGGCGCCGGCGAGCTGCAC
CTGGAGATCTGCCTGAAGGACCTGGAGGAGGACCACGCCTGCATCCCCATCAAGGTGAGGCGCCAGTGACCAGCCTTCCC
CACGCCCCACCCCGGACACCTGCCCTCTGCTTTAAAGCTGAGCTGAGCTAGGCTCTGCAGACGCCTAGACTTGATCTCGG
TCTTGGTCTCAGCTTCTTAAGTTCCTCAAGTTTCTTCTTTGCAGTCTTCCACAGGCATGTGGGGCTGTTTTTGTTGTTGT
TGTTGTTTTTTTTGAGATAGTCTCGCTGTGTCATCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCGCTAGAACCTCCA
CCTCCCGGGTTCAAGCGATTCTCTTGCCTCACTCAGCTTCCTGAGTAACTGGGACTACAGGCGCGTGCTACCACGCCCGG
CTAATTTTTTTTTGTATTTTTAGTAGAGGCGGGGTTTCACTGTGTTAGTAAGTCAAGATGGTCTCGATCTCCTGACCTCG
TGATCCCCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCCAGGGCTATTTTTTTTT
TTTTTTTTTTTTTTTTTTTGAGACAAGAGTCTTGCTCTGTTGCTTAGGCTGGAGTGCAATGGCGTGATCTTGGCTCACTG
CAAGCTCTGCTTCCCAGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGTAGCTGGGACTTCAGGCGCCTGCCATCATGCC
CGGCTAATTTTTTGCATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTGGATCTCCTGACCTCGTGAT
CCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCGGCCTCCGGGGCAGTTTTTGAGTTA
CATCCTGCTGTCTTCTGTCCACAAACAACACAAATGCTCTGGAGGGGTTGGGACAGGCCTGCTCCAGACCTCGTTTCTTC
CCTGTTAATGCTTAAAATTCCACAAGCCCGTGGTTTCTGCGCCGGAGAGCTCAGTGGAGCCCCTGCTCCTTGTCCTTGTC
TGGAGTGAGATGCGCTTGGCACTGCAACACTGACTCCGCTTCGTTCTGATTGACGTGGCTCTACCAGGCTGTATGAGGTC
CGCCTTGCTAGGAAAAGCTTTTAAGGATGCGTCTGTGTGTAAGGTCACCTCTTTCTCCAGGCAAGAGTGGGACTTAACCT
CTTTTTGCAGAAATCTGACCCGGTCGTCTCGTACCGCGAGACGGTCAGTGAAGAGTCGAACGTGCTCTGCCTCTCCAAGT
CCCCCAACAAGCACAACCGGCTGTACATGAAGGCGCGGCCCTTCCCCGACGGCCTGGCCGAGGACATCGATAAAGGCGAG
GTGTCCGCCCGTCAGGAGCTCAAGCAGCGGGCGCGCTACCTGGCCGAGAAGTACGAGTGGGACGTGGCTGAGGCCCGCAA
GATCTGGTGCTTTGGGCCCGACGGCACCGGCCCCAACATCCTCACCGACATCACCAAGGGTGTGCAGTACCTCAACGAGA
TCAAGGACAGTGTGGTGGCCGGCTTCCAGTGGGCCACCAAGGAGGTGAGGCACGGCTCAGCATGTGCAGACCACACCCGT
TTCCAGGCTCTAGAGGGACCTCATGGTCCTGCCTCCCGAGACAGAGACCCTAATGGGGCCAAGGCGGGCAAGGCCCCAGG
TCCCCCTGGTGGAGACCTGCAGGACTTGGCAGGTGGAGGGCAAGCAGCCGAGGTGTGTCCGGCCCTTGACGGTGGCTCTC
CCCCTCCCCCAGGGCGCACTGTGTGAGGAGAACATGCGGGGTGTGCGCTTCGACGTCCACGACGTCACCCTGCACGCCGA
CGCCATCCACCGCGGAGGGGGCCAGATCATCCCCACAGCACGGCGCTGCCTCTATGCCAGTGTGCTGACCGCCCAGCCAC
GCCTCATGGAGCCCATCTACCTTGTGGAGATCCAGGTGAGGTCTACCCGCCCACCGCTGACCCTGCCACCGTCCTGCCCA
GCGGCCACTGACAGGTTTTCTTTCCCTTCTGGCAGTGTCCAGAGCAGGTGGTCGGTGGCATCTACGGGGTTTTGAACAGG
AAGCGGGGCCACGTGTTCGAGGAGTCCCAGGTGGCCGGCACCCCCATGTTTGTGGTCAAGGCCTATCTGCCCGTCAACGA
GTCCTTTGGTGAGTGCCTGCCCGGTGTGGCCTGCAGAGCCTGGCAGGCTGGTTTGGGGGACAGAAGCCCAGTTAAGCTTA
GCAAGGTGTTAAAGGAGGCGTCCTGATGGGAGCAGGTGATGGATGGAGCAGGTGGTCCAGTTTCTGACAGCTTGTGGACC
CCCTAAATCACTGAATTCCCAGGGGAGGGGCTCTCCTATCCCCAGTGTGAGAAGGGCTCTGGGCCTGGAGCTCTGAAGGC
CTACGCCCTGGGCCGGTAGAGCAGCCGAGCTGTAGCACAGGGTTGTCCCAAACGAGCAGCGGCATGAGGCCCATGAGTGG
CCTGCTAGGCCCTTCGTGAAGTGCTGGGCACCAGGCCGAGTGTCTGGTCTGCAGGGTGACTCAGGCTGAGGAACTAGCCT
GAGCTCCTGACAGGACTTTCCTTCTGCCCTGCCACCTTCTCGATGGCCCAGTGAGCCTCTCGCTTCCCTCTGCAGGCTTC
ACCGCTGACCTGAGGTCCAACACGGGCGGCCAGGCGTTCCCCCAGTGTGTGTTTGACCACTGGCAGATCCTGCCCGGAGA
CCCCTTCGACAACAGCAGCCGCCCCAGCCAGGTGGTGGCGGAGACCCGCAAGCGCAAGGGCCTGAAAGAAGGCATCCCTG
CCCTGGACAACTTCCTGGACAAATTGTAGGCGGCCCTTCCTGCAGCGCCTGCCGCCCCGGGGACTCGCAGCACCCACAGC
ACCACGTCCTCGAATTCTCAGACGACACCTGGAGACTGTCCCGACACAGCGACGCTCCCCTGAGAGGTTTCTGGGGCCCG
CTGCGTGCCATCACTCAACCATAACACTTGATGCCGTTTCTTTCAATATTTATTTCCAGAGTCCGGAGGCAGCAGACACG
CCCTCTTAGTAGGGACTTAATGGGCCGGTCGGGGAGGGGGAGGCGGGATGGGACACCCAACACTTTTTCCATTTCTTCAG
AGGGAAACTCAGATGTCCAAACTAATTTTAACAAACGCATTAAGAGGTTTATTTGGGTACATGGCCCGCAGTGGCTTTTG
CCCCAGAAAGGGGAAAGGAACACGCGGGTAGATGATTTCTAGCAGGCAGGAAGTCCTGTGCGGTGTCACCATGAGCACCT
CCAGCTGTACTAGTGCCATTGGAATAATAAATTTGATAAGGTGGTGAC