(CAMKK2) calcium/calmodulin-dependent protein kinase kinase 2, beta [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  36433
 Official symbol  CAMKK2
 Official name  calcium/calmodulin-dependent protein kinase kinase 2, beta
 Gene type  protein-coding
 Organism  Homo sapiens
 Location  chromosome 12 (NC_000012.10) : 120159878...120220495  (-)
 Map  12q24.2
 Length  60617  nt
Run another request
Search by
Query

Alternative name(s) and Synynom(s) top
Synonyms MGC15254; KIAA0787; CAMKKB; CAMKK
Names calcium/calmodulin-dependent protein kinase kinase 2 beta
calcium/calmodulin-dependent protein kinase beta
CAMKK beta protein
External Links top
Ensembl ENSG00000110931
GeneID 10645
HGNC 1470
HPRD 06467
Comment top
Summary The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq].
Bibliography top
Related Articles in PubMed
Genome Browser top
Go to our internal gbrowse  gmod.org/wiki/GBrowse
Genome Context top
Go to ensembl  www.ensembl.org
Homologuous Genes top
Pathways top
Sequence top
Get sequence