| (CAPNS1) calpain, small subunit 1 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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34687
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Official symbol
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CAPNS1
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Official name
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calpain, small subunit 1
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Gene type
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protein-coding
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Organism
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Homo sapiens
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Location
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chromosome 19 (NC_000019.8) : 41322758...41333096 (+)
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Map
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19q13.12
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Length
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10338 nt
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Alternative name(s) and Synynom(s)
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| Synonyms |
CDPS; CAPN4; CANPS; CANP; CALPAIN4; 30K
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| Names |
calpain, small polypeptide
calpain 4, small subunit (30K)
calcium-dependent protease, small subunit
calcium-activated neutral proteinase
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External Links
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Comment
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| Summary |
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].
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Bibliography
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Related Articles in PubMed
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Genome Context
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Go to ensembl 
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Homologuous Genes
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Pathways
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Sequence
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Get sequence
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