(BCL2) B-cell CLL/lymphoma 2 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  34330
 Official symbol  BCL2
 Official name  B-cell CLL/lymphoma 2
 Gene type  protein-coding
 Organism  Homo sapiens
 Location  chromosome 18 (NC_000018.8) : 58941559...59137594  (-)
 Map  18q21.33|18q21.3
 Length  196035  nt
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Alternative name(s) and Synynom(s) top
Synonyms Bcl-2
Names OTTHUMP00000163680
B-cell lymphoma protein 2
External Links top
Ensembl ENSG00000171791
GeneID 596
HGNC 990
HPRD 01045
Comment top
Summary This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
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