(CAPN1) calpain 1, (mu/I) large subunit [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  29133
 Official symbol  CAPN1
 Official name  calpain 1, (mu/I) large subunit
 Gene type  protein-coding
 Organism  Homo sapiens
 Location  chromosome 11 (NC_000011.8) : 64705919...64736053  (+)
 Map  11q13
 Length  30134  nt
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Alternative name(s) and Synynom(s) top
Synonyms muCL; muCANP; CANPL1; CANP1; CANP
Names cell proliferation-inducing protein 30
calpain, large polypeptide L1
calpain 1, large subunit
calcium-activated neutral proteinase
External Links top
EC_number 3.4.22.17
GeneID 823
HGNC 1476
HPRD 00253
Comment top
Summary The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. [provided by RefSeq].
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