(BNIP3) BCL2/adenovirus E1B 19kDa interacting protein 3 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  28502
 Official symbol  BNIP3
 Official name  BCL2/adenovirus E1B 19kDa interacting protein 3
 Gene type  protein-coding
 Organism  Homo sapiens
 Location  chromosome 10 (NC_000010.9) : 133631194...133645426  (-)
 Map  10q26.3
 Length  14232  nt
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Alternative name(s) and Synynom(s) top
Synonyms NIP3
Names OTTHUMP00000020752
BCL2/adenovirus E1B 19kD-interacting protein 3
External Links top
Ensembl ENSG00000176171
GeneID 664
HGNC 1084
HPRD 04482
Comment top
Summary This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq].
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