(BAG1) BCL2-associated athanogene [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  28021
 Official symbol  BAG1
 Official name  BCL2-associated athanogene
 Gene type  protein-coding
 Organism  Homo sapiens
 Location  chromosome 9 (NC_000009.10) : 33242469...33254762  (-)
 Map  9p12
 Length  12293  nt
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Alternative name(s) and Synynom(s) top
Synonyms RAP46
Names BCL2-associated athanogene 1
External Links top
Ensembl ENSG00000107262
GeneID 573
HGNC 937
HPRD 03292
Comment top
Summary The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites. [provided by RefSeq].
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