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Alternative name(s) and Synynom(s)
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| Synonyms |
WHIM; NPYY3R; NPYRL; NPYR; NPY3R; LESTR; LCR1; LAP3; HSY3RR; HM89; FB22; D2S201E; CD184
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| Names |
stromal cell-derived factor 1 receptor
seven-transmembrane-segment receptor, spleen
seven transmembrane helix receptor
neuropeptide Y receptor Y3
lipopolysaccharide-associated protein 3
leukocyte-derived seven-transmembrane-domain receptor
fusin
chemokine receptor 4
chemokine (C-X-C motif), receptor 4 (fusin)
CD184 antigen
C-X-C chemokine receptor type 4
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External Links
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Comment
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| Summary |
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
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Bibliography
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Related Articles in PubMed
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Genome Browser
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Genome Context
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Go to ensembl 
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Homologuous Genes
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Pathways
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Sequence
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Get sequence
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