| (ATG4C) ATG4 autophagy related 4 homolog C (S. cerevisiae) [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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22656
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Official symbol
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ATG4C
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Official name
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ATG4 autophagy related 4 homolog C (S. cerevisiae)
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Gene type
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protein-coding
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Organism
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Homo sapiens
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Location
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chromosome 1 (NC_000001.9) : 63022391...63102639 (+)
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Map
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1p31.3
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Length
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80248 nt
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Alternative name(s) and Synynom(s)
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| Synonyms |
FLJ14867; AUTL3; AUTL1; APG4C; APG4-C
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| Names |
APG4 autophagy 4 homolog C (S. cerevisiae)
AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae)
autophagy-related cysteine endopeptidase 3
autophagin-3
OTTHUMP00000010715
AUT-like 3 cysteine endopeptidase
AUT-like 1, cysteine endopeptidase
APG4 autophagy 4 homolog C
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External Links
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Comment
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| Summary |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq].
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Bibliography
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Related Articles in PubMed
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Genome Browser
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Genome Context
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Go to ensembl 
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Homologuous Genes
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Pathways
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Sequence
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Get sequence
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