| (CAPN2) calpain 2, (m/II) large subunit [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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22611
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Official symbol
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CAPN2
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Official name
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calpain 2, (m/II) large subunit
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Gene type
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protein-coding
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Organism
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Homo sapiens
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Location
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chromosome 1 (NC_000001.9) : 221966742...222030344 (+)
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Map
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1q41-q42
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Length
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63602 nt
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Alternative name(s) and Synynom(s)
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| Synonyms |
mCANP; FLJ39928; CANPml; CANPL2; CANP2
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| Names |
millimolar-calpain
calpain, large polypeptide L2
calpain M-type
calpain 2, large subunit
calpain 2, large [catalytic] subunit
calcium-activated neutral proteinase
OTTHUMP00000035497
M-calpain
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External Links
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Comment
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| Summary |
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. [provided by RefSeq].
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Bibliography
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Related Articles in PubMed
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Genome Context
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Homologuous Genes
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Pathways
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Sequence
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Get sequence
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